Detailed information for compound 518253

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 809.284 | Formula: C38H41ClN6O10S
  • H donors: 4 H acceptors: 9 LogP: 6.08 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)c1ccc2c(c1)oc(n2)C(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)c1ccc(cc1)NC(=O)NS(=O)(=O)c1ccc(cc1)Cl
  • InChi: 1S/C38H41ClN6O10S/c1-20(2)30(32(46)35-41-27-17-10-23(37(50)54-5)19-29(27)55-35)42-34(48)28-7-6-18-45(28)36(49)31(21(3)4)43-33(47)22-8-13-25(14-9-22)40-38(51)44-56(52,53)26-15-11-24(39)12-16-26/h8-17,19-21,28,30-31H,6-7,18H2,1-5H3,(H,42,48)(H,43,47)(H2,40,44,51)/t28-,30-,31-/m0/s1
  • InChiKey: CTTGHLSRCCAZJA-ASVWTAOFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens elastase, neutrophil expressed Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus transmembrane protease serine 3 elastase, neutrophil expressed 267 aa 236 aa 27.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.2895
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0197 0.0737 0.2424
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0017 0.0001 0.0001
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.0115 0.0114
Leishmania major hypothetical protein, conserved 0.0045 0.0115 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0272
Leishmania major cathepsin L-like protease 0.086 0.345 0.5192
Brugia malayi cathepsin L-like cysteine proteinase 0.0197 0.0737 0.0736
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.003 0.0053 0.0052
Entamoeba histolytica prolyl oligopeptidase family protein 0.0197 0.0737 0.2426
Plasmodium falciparum plasmepsin X 0.0109 0.0377 0.124
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0207 0.0206
Onchocerca volvulus 0.0197 0.0737 0.1109
Loa Loa (eye worm) hypothetical protein 0.0061 0.0181 0.018
Brugia malayi Animal haem peroxidase family protein 0.013 0.0464 0.0463
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0099 0.0272
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0018 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0043
Trypanosoma cruzi kinesin, putative 0.0512 0.2027 0.2026
Echinococcus granulosus expressed protein 0.0804 0.3223 0.3223
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0669 0.2669 1
Brugia malayi hypothetical protein 0.0041 0.0099 0.0098
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.005 0.0049
Plasmodium falciparum plasmepsin II 0.003 0.0053 0.0172
Schistosoma mansoni flap endonuclease-1 0.0024 0.0027 0.0027
Loa Loa (eye worm) aspartic protease BmAsp-2 0.003 0.0053 0.0052
Echinococcus multilocularis programmed cell death protein 0.0121 0.0425 0.0424
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Entamoeba histolytica calmodulin, putative 0.0117 0.041 0.135
Loa Loa (eye worm) hypothetical protein 0.2459 1 1
Onchocerca volvulus 0.0029 0.005 0.0075
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0099 0.0099
Plasmodium vivax unspecified product 0.0424 0.1668 0.5496
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Onchocerca volvulus Prolyl endopeptidase homolog 0.1639 0.6644 1
Plasmodium falciparum plasmepsin III 0.003 0.0053 0.0172
Trypanosoma cruzi kinesin, putative 0.0512 0.2027 0.2026
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0737 0.2043
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0211 0.0316
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0015
Echinococcus granulosus proteasome prosome macropain 0.0088 0.0292 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0099 0.0099
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.009 0.0153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0272
Echinococcus granulosus cathepsin L 0.0197 0.0737 0.0736
Trypanosoma brucei hypothetical protein, conserved 0.0117 0.041 0.0616
Giardia lamblia Cysteine protease 0.0197 0.0737 0.2043
Schistosoma mansoni calmodulin 0.0117 0.041 0.041
Echinococcus multilocularis EF hand domain containing family member A2 0.0117 0.041 0.041
Toxoplasma gondii hypothetical protein 0.0029 0.005 0.0073
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0017 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0197 0.0737 0.2044
Giardia lamblia Cathepsin L precursor 0.0197 0.0737 0.2043
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0531 0.2103 0.2103
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0018 0.0017
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0181 0.0273
Trichomonas vaginalis hypothetical protein 0.0212 0.0799 0.2215
Brugia malayi Trypsin family protein 0.0168 0.0618 0.0617
Brugia malayi hypothetical protein 0.0091 0.0302 0.0301
Echinococcus granulosus caspase 2 0.0061 0.0181 0.018
Brugia malayi prolyl oligopeptidase family protein 0.0197 0.0737 0.0736
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0092 0.0305 0.0522
Schistosoma mansoni neprilysin-2 (M13 family) 0.0046 0.0119 0.0119
Echinococcus granulosus cathepsin l cysteine peptidase 0.0758 0.3035 0.3034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0737 0.0737
Trichomonas vaginalis calpain, putative 0.0212 0.0799 0.2215
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0037 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Trypanosoma cruzi major cysteine proteinase, putative 0.0298 0.1152 0.1151
Entamoeba histolytica glycogen phosphorylase, putative 0.0119 0.0415 0.1366
Entamoeba histolytica cysteine proteinase, putative 0.0424 0.1668 0.5496
Trypanosoma brucei caltractin, putative 0.0121 0.0425 0.0638
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0052
Plasmodium falciparum serine repeat antigen 5 0.0197 0.0737 0.2424
Brugia malayi hypothetical protein 0.003 0.0053 0.0052
Brugia malayi PXA domain containing protein 0.0041 0.0099 0.0098
Brugia malayi Cathepsin L-like precursor 0.0228 0.0862 0.0861
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0197 0.0737 0.2424
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0758 0.3035 0.3034
Leishmania major centrin, putative,caltractin, putative 0.0117 0.041 0.0616
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0443 0.0442
Echinococcus granulosus calpain 5 0.0724 0.2895 0.2895
Onchocerca volvulus 0.0758 0.3035 0.4568
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0088 0.0292 0.0291
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.005 0.0073
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0758 0.3035 1
Mycobacterium ulcerans putative transglutaminase-like protein 0.0174 0.0643 0.2407
Entamoeba histolytica calcium-binding protein, putative 0.0117 0.041 0.135
Plasmodium falciparum plasmepsin V 0.003 0.0053 0.0172
Brugia malayi calpain D 0.0212 0.0799 0.0798
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Loa Loa (eye worm) hypothetical protein 0.0091 0.0302 0.0301
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0104 0.0103
Echinococcus granulosus Mastin 0.0168 0.0618 0.0617
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0197 0.0737 0.0737
Brugia malayi Calmodulin-like protein 0.0117 0.041 0.041
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0643 0.11
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0393 0.1538 0.1538
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0212 0.0799 0.2215
Loa Loa (eye worm) hypothetical protein 0.0531 0.2103 0.2103
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0099 0.0098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0139 0.0138
Leishmania major i/6 autoantigen-like protein 0.0117 0.041 0.0616
Brugia malayi Peptidase family M13 containing protein 0.0092 0.0305 0.0304
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0098
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Onchocerca volvulus 0.0168 0.0618 0.0931
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0099 0.0099
Echinococcus granulosus programmed cell death protein 0.0121 0.0425 0.0424
Entamoeba histolytica hypothetical protein 0.0197 0.0737 0.2424
Echinococcus multilocularis endothelin converting enzyme 1 0.0092 0.0305 0.0304
Trypanosoma cruzi cysteine proteinase, putative 0.0424 0.1668 0.1668
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0737 0.0737
Entamoeba histolytica cysteine proteinase, putative 0.0424 0.1668 0.5496
Toxoplasma gondii PAN domain-containing protein 0.0029 0.005 0.0073
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2459 1 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.009 1
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Trypanosoma brucei centrin, putative 0.0117 0.041 0.0616
Leishmania major cathepsin L-like protease 0.0758 0.3035 0.4568
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0018 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0424 0.1668 0.251
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0197 0.0737 0.2043
Brugia malayi Papain family cysteine protease containing protein 0.0197 0.0737 0.0736
Trypanosoma cruzi hypothetical protein, conserved 0.0197 0.0737 0.0736
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0017 0.0001 0.0001
Onchocerca volvulus 0.0174 0.0643 0.0968
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Echinococcus granulosus cathepsin b 0.2459 1 1
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0211 0.0211
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.007 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0424 0.1668 0.251
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Brugia malayi Cathepsin L-like cysteine proteinase 0.0531 0.2103 0.2103
Entamoeba histolytica cysteine protease, putative 0.0197 0.0737 0.2424
Loa Loa (eye worm) hypothetical protein 0.0069 0.0214 0.0213
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.009 0.5
Brugia malayi Serine carboxypeptidase S28 family protein 0.0021 0.0016 0.0015
Onchocerca volvulus 0.0029 0.005 0.0075
Plasmodium falciparum plasmepsin VII 0.003 0.0053 0.0172
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0018 0.0018
Schistosoma mansoni glycogen phosphorylase 0.0119 0.0415 0.0415
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0018 0.0027
Leishmania major hypothetical protein, conserved 0.0119 0.0419 0.0629
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0018 0.0018
Plasmodium falciparum plasmepsin VIII, putative 0.003 0.0053 0.0172
Entamoeba histolytica cysteine protease, putative 0.0758 0.3035 1
Loa Loa (eye worm) hypothetical protein 0.0134 0.0479 0.0478
Loa Loa (eye worm) hypothetical protein 0.1933 0.7846 0.7845
Trypanosoma cruzi cysteine peptidase, putative 0.0424 0.1668 0.1668
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0017 0.0001 0.0001
Schistosoma mansoni cathepsin S (C01 family) 0.0197 0.0737 0.0737
Onchocerca volvulus 0.0029 0.005 0.0075
Onchocerca volvulus 0.003 0.0053 0.008
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0104 0.034
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0197 0.0737 0.2424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Echinococcus granulosus neurocalcin 0.0117 0.041 0.041
Giardia lamblia Cathepsin B precursor 0.0197 0.0737 0.2043
Echinococcus multilocularis inhibitor of apoptosis protein 0.0134 0.0479 0.0478
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0099 0.0098
Toxoplasma gondii cathepsin CPC1 0.0197 0.0737 0.1107
Mycobacterium ulcerans zinc metalloprotease 0.0092 0.0305 0.1141
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0617
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0228 0.0862 0.0861
Toxoplasma gondii aspartyl protease ASP1 0.003 0.0053 0.0078
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0088 0.0292 0.0958
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0724 0.2895 0.2895
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0424 0.1668 0.1668
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0117 0.041 0.0616
Brugia malayi Papain family cysteine protease containing protein 0.0424 0.1668 0.1668
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0197 0.0737 0.2424
Loa Loa (eye worm) calpain D 0.0212 0.0799 0.0798
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0523 0.2072 0.3119
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0212 0.0799 0.2215
Onchocerca volvulus 0.0119 0.0419 0.0631
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0197 0.0737 0.2043
Giardia lamblia Hypothetical protein 0.0197 0.0737 0.2043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0212 0.0799 0.0798
Loa Loa (eye worm) hypothetical protein 0.0045 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0255 0.0972 0.0971
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0099 0.0098
Plasmodium vivax vivapain-2 0.0758 0.3035 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0737 0.2043
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0021 0.0016 0.0015
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Echinococcus multilocularis expressed protein 0.0804 0.3223 0.3223
Entamoeba histolytica glycogenphosphorylase, putative 0.0051 0.014 0.0457
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0099 0.0098
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0018 0.0017
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0037 0.0055
Schistosoma mansoni centrin-related 0.0117 0.041 0.041
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0228 0.0862 0.0861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Entamoeba histolytica calmodulin, putative 0.0117 0.041 0.135
Schistosoma mansoni hypothetical protein 0.0168 0.0618 0.0618
Echinococcus granulosus cathepsin L 0.0424 0.1668 0.1668
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0018 0.0017
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0896 0.3602 0.3601
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Echinococcus multilocularis neurocalcin 0.0117 0.041 0.041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0018 0.0017
Echinococcus multilocularis EF hand domain containing family member A2 0.0119 0.0419 0.0418
Loa Loa (eye worm) glycogen phosphorylase 0.0119 0.0415 0.0414
Brugia malayi prolyl oligopeptidase family protein 0.0288 0.1109 0.1109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0099 0.0098
Toxoplasma gondii EF hand domain-containing protein 0.0117 0.041 0.0616
Trypanosoma brucei calpain-like protein, putative 0.0724 0.2895 0.4357
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0099 0.0098
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0197 0.0737 0.0737
Echinococcus granulosus glycoprotein Antigen 5 0.0168 0.0618 0.0617
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Schistosoma mansoni inhibitor of apoptosis protein 0.0134 0.0479 0.0479
Echinococcus multilocularis calpain 0.0724 0.2895 0.2895
Schistosoma mansoni cathepsin B (C01 family) 0.0197 0.0737 0.0737
Entamoeba histolytica cysteine proteinase, putative 0.0424 0.1668 0.5496
Echinococcus granulosus cpg binding protein 0.0033 0.0065 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0758 0.3035 0.8427
Trypanosoma cruzi centrin, putative 0.0121 0.0425 0.0424
Leishmania major hypothetical protein, unknown function 0.0212 0.0799 0.1201
Brugia malayi Papain family cysteine protease containing protein 0.0424 0.1668 0.1668
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Brugia malayi Kringle domain containing protein 0.0045 0.0115 0.0114
Toxoplasma gondii kringle domain-containing protein 0.0045 0.0115 0.0171
Brugia malayi hypothetical protein 0.0041 0.0099 0.0098
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0211 0.0692
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0016 0.0051
Loa Loa (eye worm) aspartic protease BmAsp-1 0.003 0.0053 0.0052
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0018 0.0017
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Onchocerca volvulus 0.0531 0.2103 0.3166
Trypanosoma cruzi cruzipain precursor, putative 0.086 0.345 0.345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Brugia malayi hypothetical protein 0.0061 0.0181 0.018
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.003 0.0053 0.0078
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0017 0.0001 0.0001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.205 0.8326 0.8326
Giardia lamblia Cathepsin L precursor 0.0197 0.0737 0.2043
Giardia lamblia Cathepsin B precursor 0.0197 0.0737 0.2043
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.009 0.0293
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0669 0.2669 1
Leishmania major programmed cell death 6 protein-like protein 0.0117 0.041 0.0616
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0017 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0018 0.0017
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0099 0.0098
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0099 0.0098
Giardia lamblia Cathepsin L precursor 0.0197 0.0737 0.2043
Plasmodium falciparum cysteine proteinase falcipain 3 0.0758 0.3035 1
Entamoeba histolytica cysteine protease, putative 0.0197 0.0737 0.2424
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0632 0.2518 0.2518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0737 0.2043
Brugia malayi aspartic protease BmAsp-2, identical 0.003 0.0053 0.0052
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.009 0.0089
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0724 0.2895 0.4357
Leishmania major calpain protease-like protein 0.0212 0.0799 0.1201
Loa Loa (eye worm) hypothetical protein 0.0758 0.3035 0.3034
Leishmania major calmodulin, putative 0.0117 0.041 0.0616
Loa Loa (eye worm) hypothetical protein 0.1639 0.6644 0.6644
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0272
Onchocerca volvulus Notchless protein homolog 0.0017 0.0001 0.0002
Brugia malayi Cytochrome P450 family protein 0.0034 0.007 0.0069
Giardia lamblia Glycogen phosphorylase 0.0119 0.0415 0.1151
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0099 0.0098
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0099 0.0098
Giardia lamblia Serine peptidase, putative 0.0021 0.0016 0.0043
Loa Loa (eye worm) hypothetical protein 0.0061 0.0181 0.018
Toxoplasma gondii calcium-dependent protein kinase 0.0119 0.0419 0.0629
Toxoplasma gondii prolyl endopeptidase 0.1639 0.6644 1
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0117 0.041 0.041
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0018 0.0018
Echinococcus granulosus cathepsin L cysteine protease 0.0424 0.1668 0.1668
Onchocerca volvulus 0.013 0.0464 0.0698
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0018 0.0017
Echinococcus granulosus Glycosyl transferase family 35 0.0119 0.0415 0.0414
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0737 0.0737
Trypanosoma brucei centrin-3 0.0121 0.0425 0.0638
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0037 0.0101
Giardia lamblia Hypothetical protein 0.0197 0.0737 0.2043
Brugia malayi Cathepsin L-like precursor 0.0758 0.3035 0.3034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0315 0.0315
Entamoeba histolytica cysteine proteinase, putative 0.0758 0.3035 1
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Loa Loa (eye worm) hypothetical protein 0.0069 0.0214 0.0213
Trypanosoma brucei Calpain-like protein 2 0.0212 0.0799 0.1201
Onchocerca volvulus 0.0045 0.0116 0.0175
Plasmodium falciparum serine repeat antigen 7 0.0197 0.0737 0.2424
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0288 0.1109 0.1109
Echinococcus multilocularis cpg binding protein 0.0033 0.0065 0.0064
Schistosoma mansoni hypothetical protein 0.0212 0.0799 0.0799
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0104 0.034
Echinococcus multilocularis transmembrane protease serine 3 0.0168 0.0618 0.0617
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Brugia malayi calpain family protein 1 0.1933 0.7846 0.7845
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0197 0.0737 0.2043
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Onchocerca volvulus Cathepsin L homolog 0.0758 0.3035 0.4568
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0212 0.0799 0.0798
Echinococcus granulosus tumor protein p63 0.0368 0.1438 0.1437
Plasmodium falciparum plasmepsin VI 0.003 0.0053 0.0172
Brugia malayi nuclear hormone receptor 0.0022 0.0018 0.0017
Plasmodium vivax aspartyl protease, putative 0.0109 0.0377 0.124
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Toxoplasma gondii cathepsin B 0.0896 0.3602 0.542
Echinococcus multilocularis dnaJ subfamily B 0.0445 0.1753 0.1752
Schistosoma mansoni coup transcription factor 0.0022 0.0018 0.0018
Schistosoma mansoni peroxidasin 0.013 0.0464 0.0464
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0018 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2459 1 1
Onchocerca volvulus 0.0029 0.005 0.0075
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Plasmodium vivax unspecified product 0.0228 0.0862 0.2837
Toxoplasma gondii proteasome subunit beta type, putative 0.0088 0.0292 0.0438
Loa Loa (eye worm) prolyl oligopeptidase 0.0523 0.2072 0.2071
Giardia lamblia Thymus-specific serine protease precursor 0.0021 0.0016 0.0043
Brugia malayi EF hand family protein 0.0119 0.0419 0.0418
Echinococcus granulosus calcium uptake protein 1 0.0119 0.0419 0.0418
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0197 0.0737 0.2043
Trypanosoma brucei cysteine peptidase C (CPC) 0.0896 0.3602 0.542
Entamoeba histolytica cysteine protease, putative 0.0197 0.0737 0.2424
Onchocerca volvulus 0.0758 0.3035 0.4568
Brugia malayi Trypsin family protein 0.0168 0.0618 0.0617
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0197 0.0737 0.2043
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0669 0.2669 0.4017
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0017 0.0001 0.0001
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.205 0.8326 0.8326
Toxoplasma gondii microneme protein, putative 0.0029 0.005 0.0073
Onchocerca volvulus 0.0029 0.005 0.0075
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0117 0.041 0.041
Trichomonas vaginalis calmodulin, putative 0.0119 0.0419 0.1161
Brugia malayi calpain 5 0.0212 0.0799 0.0798
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0099 0.0098
Leishmania major hypothetical protein, conserved 0.0212 0.0799 0.1201
Schistosoma mansoni neuronal calcium sensor 0.0117 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0098
Schistosoma mansoni cpg binding protein 0.0033 0.0065 0.0065
Echinococcus multilocularis acylamino acid releasing enzyme 0.0197 0.0737 0.0736
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0139 0.0138
Echinococcus granulosus cathepsin L cysteine proteinase 0.0758 0.3035 0.3034
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0197 0.0737 0.2043
Giardia lamblia Cysteine protease 0.0197 0.0737 0.2043
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0197 0.0737 0.0736
Onchocerca volvulus Dual oxidase homolog 0.013 0.0464 0.0698
Giardia lamblia Cathepsin L precursor 0.0197 0.0737 0.2043
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0017 0.0001 0.0001
Plasmodium falciparum serine repeat antigen 4 0.0197 0.0737 0.2424
Trypanosoma cruzi calmodulin, putative 0.0117 0.041 0.041
Plasmodium vivax hypothetical protein, conserved 0.0197 0.0737 0.2426
Plasmodium vivax vivapain-3 0.0424 0.1668 0.5496
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0803 0.3219 0.3218
Brugia malayi proteasome subunit beta type 2 0.0043 0.0104 0.0103
Entamoeba histolytica hypothetical protein, conserved 0.0197 0.0737 0.2426
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0021 0.0021
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0211 0.021
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0018 0.0018
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0168 0.0618 0.0618
Trichomonas vaginalis calcium binding protein, putative 0.0117 0.041 0.1137
Trypanosoma brucei cysteine peptidase, putative 0.0212 0.0799 0.1201
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0053 0.0172
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0669 0.2669 0.4572
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0896 0.3602 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Leishmania major phospholipase c-like protein 0.0117 0.041 0.0616
Schistosoma mansoni calpain-7 (C02 family) 0.0727 0.2907 0.2907
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0098
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Echinococcus multilocularis glycogen phosphorylase 0.0119 0.0415 0.0414
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Loa Loa (eye worm) hypothetical protein 0.0092 0.0305 0.0304
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0018 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0456 0.1707
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0117 0.041 0.135
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.0115 0.0375
Toxoplasma gondii aspartyl protease 0.003 0.0053 0.0078
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0018 0.0017
Trypanosoma cruzi calmodulin, putative 0.0117 0.041 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Echinococcus granulosus calpain 0.0724 0.2895 0.2895
Giardia lamblia Cathepsin B precursor 0.0197 0.0737 0.2043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0017 0.0001 0.0001
Loa Loa (eye worm) EF hand family protein 0.0117 0.041 0.041
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0018 0.0017
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.007 0.0257
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0737 0.2043
Plasmodium vivax vivapain-1 0.0424 0.1668 0.5496
Loa Loa (eye worm) hypothetical protein 0.0092 0.0305 0.0304
Loa Loa (eye worm) aspartyl protease 6 0.003 0.0053 0.0052
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0197 0.0737 0.1108
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0197 0.0737 0.2424
Loa Loa (eye worm) hypothetical protein 0.0069 0.0214 0.0213
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0211 0.021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0212 0.0799 0.0798
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0117 0.041 0.041
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0046 0.0119 0.0119
Brugia malayi hypothetical protein 0.013 0.0464 0.0463
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0119 0.0419 0.0418
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0099 0.0098
Entamoeba histolytica calpain large subunit domain III containing protein 0.0512 0.2027 0.6677
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Leishmania major calmodulin, putative 0.0117 0.041 0.0616
Schistosoma mansoni calmodulin related calcium binding protein 0.0117 0.041 0.041
Brugia malayi Thioredoxin family protein 0.0174 0.0643 0.0642
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Onchocerca volvulus 0.0168 0.0618 0.0931
Trypanosoma brucei Calpain-like protein CALP1.3 0.0212 0.0799 0.1201
Echinococcus granulosus EF hand domain containing family member A2 0.0117 0.041 0.041
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.0315 0.0315
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.009 0.0089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0018 0.0017
Brugia malayi prolyl oligopeptidase family protein 0.0523 0.2072 0.2071
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0197 0.0737 0.2426
Schistosoma mansoni neuronal calcium sensor 0.0117 0.041 0.041
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.005 0.0073
Brugia malayi Animal haem peroxidase family protein 0.013 0.0464 0.0463
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0464 0.0463
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0117 0.041 0.041
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0018 0.0017
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0212 0.0799 0.1201
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Toxoplasma gondii hypothetical protein 0.0029 0.005 0.0073
Onchocerca volvulus Deterin homolog 0.0134 0.0479 0.0721
Trypanosoma brucei centrin, putative 0.0117 0.041 0.0616
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0037 0.012
Echinococcus granulosus transmembrane protease serine 3 0.0168 0.0618 0.0617
Schistosoma mansoni cathepsin D (A01 family) 0.0122 0.0432 0.0432
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0018 0.0017
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Brugia malayi Cathepsin L-like precursor 0.0758 0.3035 0.3034
Schistosoma mansoni calpain C (C02 family) 0.0724 0.2895 0.2895
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0168 0.0618 0.0617
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0531 0.2103 0.5839
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Echinococcus granulosus Transglutaminase 0.0174 0.0643 0.0642
Mycobacterium leprae probable zinc metalloprotease 0.0092 0.0305 0.1141
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0288 0.1109 0.1109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0211 0.021
Onchocerca volvulus Peroxidasin homolog 0.013 0.0464 0.0698
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0288 0.1109 0.1109
Onchocerca volvulus Peroxidase homolog 0.013 0.0464 0.0698
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Onchocerca volvulus 0.013 0.0464 0.0698
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0523 0.2072 0.2071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0018 0.0017
Entamoeba histolytica grainin 2 0.0121 0.0425 0.1397
Brugia malayi cathepsin F-like cysteine proteinase 0.0228 0.0862 0.0861
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0099 0.0098
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0099 0.0098
Mycobacterium ulcerans hypothetical protein 0.0174 0.0643 0.2407
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0017 0.0001 0.0001
Loa Loa (eye worm) zinc metallopeptidase 4 0.0022 0.0021 0.002
Brugia malayi prolyl oligopeptidase family protein 0.1639 0.6644 0.6644
Loa Loa (eye worm) hypothetical protein 0.0045 0.0116 0.0115
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0088 0.0292 0.0438
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Loa Loa (eye worm) hypothetical protein 0.0068 0.0207 0.0206
Trichomonas vaginalis calcium binding protein, putative 0.0117 0.041 0.1137
Loa Loa (eye worm) trypsin family protein 0.0168 0.0618 0.0617
Schistosoma mansoni gamma-secretase subunit aph-1 0.025 0.0954 0.0954
Giardia lamblia Cysteine protease 0.0197 0.0737 0.2043
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0212 0.0799 0.1201
Brugia malayi Trypsin-like protease protein 5 0.0168 0.0618 0.0617
Entamoeba histolytica cysteine proteinase 1, putative 0.0424 0.1668 0.5496
Loa Loa (eye worm) calpain family protein 1 0.1421 0.5749 0.5748
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.009 0.0089
Trichomonas vaginalis myosin light chain 1, putative 0.0117 0.041 0.1137
Onchocerca volvulus 0.1209 0.488 0.7345
Trypanosoma brucei prolyl endopeptidase 0.1639 0.6644 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0161 0.016
Echinococcus multilocularis hypothetical protein 0.0724 0.2895 0.2895
Echinococcus granulosus enteropeptidase 0.0168 0.0618 0.0617
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0099 0.0098
Brugia malayi Peroxidasin 0.013 0.0464 0.0463
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.005 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0424 0.1668 0.4631
Onchocerca volvulus 0.013 0.0464 0.0698
Brugia malayi Serine protease Z688.6 precursor 0.0021 0.0016 0.0015
Echinococcus multilocularis proteasome (prosome, macropain) 0.0088 0.0292 0.0291
Toxoplasma gondii centrin 0.0117 0.041 0.0616
Plasmodium vivax SET domain protein, putative 0.0094 0.0315 0.1034
Entamoeba histolytica protein kinase, putative 0.0512 0.2027 0.6677
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0018 0.0017
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Trypanosoma cruzi cysteine protease, putative 0.0424 0.1668 0.1668
Giardia lamblia Cathepsin L precursor 0.0197 0.0737 0.2043
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Schistosoma mansoni cathepsin s 0.0228 0.0862 0.0862
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0021 0.0016 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.0228 0.0862 0.0861
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0424 0.1668 0.1668
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Trypanosoma cruzi cruzipain precursor, putative 0.0228 0.0862 0.0861
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.007 0.0069
Plasmodium falciparum proteasome subunit beta type-5 0.0088 0.0292 0.0958
Schistosoma mansoni calpain-7 (C02 family) 0.0727 0.2907 0.2907
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Leishmania major cathepsin L-like protease 0.0758 0.3035 0.4568
Echinococcus multilocularis peroxidasin 0.013 0.0464 0.0463
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0197 0.0737 0.0737
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0104 0.0155
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0298 0.0297
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Onchocerca volvulus 0.0758 0.3035 0.4568
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.009 0.0134
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0099 0.0098
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0117 0.041 0.135
Trichomonas vaginalis calcium binding proteins, putative 0.0117 0.041 0.1137
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0117 0.041 0.135
Echinococcus granulosus endothelin converting enzyme 1 0.0092 0.0305 0.0304
Trypanosoma cruzi Aph-1 protein, putative 0.0097 0.0329 0.0328
Schistosoma mansoni peroxidasin 0.013 0.0464 0.0464
Schistosoma mansoni neprilysin 0.0024 0.0028 0.0028
Toxoplasma gondii PAN domain-containing protein 0.0029 0.005 0.0073
Schistosoma mansoni hypothetical protein 0.0175 0.0646 0.0646
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0018 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Onchocerca volvulus 0.0061 0.0181 0.0273
Giardia lamblia Alanyl dipeptidyl peptidase 0.0197 0.0737 0.2044
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0228 0.0862 0.0861
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0272
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.009 0.0089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0724 0.2895 0.2895
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0139 0.0138
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0099 0.0098
Toxoplasma gondii aspartyl protease ASP3 0.0109 0.0377 0.0567
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0117 0.041 0.041
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.007 0.0069
Brugia malayi Pepsin A precursor 0.003 0.0053 0.0052
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1933 0.7846 0.7846
Trypanosoma brucei I/6 autoantigen 0.0117 0.041 0.0616
Brugia malayi Cathepsin L-like precursor 0.0531 0.2103 0.2103
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1639 0.6644 1
Toxoplasma gondii PAN domain-containing protein 0.0029 0.005 0.0073
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0018 0.0017
Brugia malayi Proteasome A-type and B-type family protein 0.0088 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0088 0.0292 0.0807
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.0456 0.0686
Schistosoma mansoni ef hand domain family member A2 0.0117 0.041 0.041
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0099 0.0099
Trypanosoma brucei prolyl oligopeptidase, putative 0.0669 0.2669 0.4017
Entamoeba histolytica cysteine proteinase, putative 0.0531 0.2103 0.6929
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.205 0.8326 0.8326
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1442 0.5837 1
Trypanosoma cruzi cysteine peptidase, putative 0.086 0.345 0.345
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0197 0.0737 0.2044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0139 0.0138
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0104 0.0104
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0643 0.11
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Trichomonas vaginalis glycogen phosphorylase, putative 0.0119 0.0415 0.1151
Brugia malayi cathepsin Z-like cysteine proteinase 0.0197 0.0737 0.0736
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.0456 0.0455
Brugia malayi Papain family cysteine protease containing protein 0.0758 0.3035 0.3034
Trypanosoma cruzi hypothetical protein, conserved 0.0197 0.0737 0.0736
Echinococcus granulosus acylamino acid releasing enzyme 0.0197 0.0737 0.0736
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0197 0.0737 0.2043
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0016 0.0043
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.009 0.0247
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0018 0.0017
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0018 0.0018
Toxoplasma gondii exonuclease III APE 0.0039 0.009 0.0134
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.2895
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Plasmodium vivax plasmepsin IV, putative 0.003 0.0053 0.0172
Trypanosoma cruzi oligopeptidase b 0.0669 0.2669 0.2668
Trypanosoma cruzi calmodulin, putative 0.0117 0.041 0.041
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0197 0.0737 0.2424
Echinococcus multilocularis cathepsin L cysteine protease 0.0758 0.3035 0.3034
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Brugia malayi Papain family cysteine protease containing protein 0.0197 0.0737 0.0736
Giardia lamblia Cathepsin L precursor 0.0197 0.0737 0.2043
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0068 0.0207 0.0206
Brugia malayi Cathepsin L-like precursor 0.0531 0.2103 0.2103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0088 0.0292 0.0807
Brugia malayi Animal haem peroxidase family protein 0.013 0.0464 0.0463
Giardia lamblia Alanyl dipeptidyl peptidase 0.0197 0.0737 0.2044
Toxoplasma gondii hypothetical protein 0.0197 0.0737 0.1108
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0288 0.1109 0.1669
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0099 0.0098
Mycobacterium tuberculosis Long conserved protein 0.0174 0.0643 0.11
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0197 0.0737 0.2424
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0022 0.0021 0.0021
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0017 0.0001 0.0001
Plasmodium falciparum serine repeat antigen 2 0.0197 0.0737 0.2424
Trypanosoma cruzi Aph-1 protein, putative 0.0097 0.0329 0.0328
Trypanosoma brucei calpain-like protein, putative 0.0724 0.2895 0.4357
Trypanosoma brucei kinesin, putative 0.0512 0.2027 0.305
Brugia malayi Cytochrome P450 family protein 0.0056 0.0161 0.016
Brugia malayi gamma-secretase subunit aph-1 0.025 0.0954 0.0953
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.009 0.0293
Loa Loa (eye worm) hypothetical protein 0.1209 0.488 0.4879
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Mycobacterium leprae Conserved hypothetical protein 0.0174 0.0643 0.2407
Trichomonas vaginalis calcineurin B subunit, putative 0.0119 0.0419 0.1161
Trypanosoma brucei calpain, putative 0.0212 0.0799 0.1201
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0104 0.0104
Echinococcus multilocularis calpain family protein 1, d 0.1421 0.5749 0.5748
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0051 0.014 0.052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Schistosoma mansoni microtubule-associated protein tau 0.1453 0.5881 0.5881
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Echinococcus multilocularis cysteine protease 0.0758 0.3035 0.3034
Brugia malayi carbohydrate phosphorylase 0.0119 0.0415 0.0414
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.0456 0.0686
Schistosoma mansoni glycogen phosphorylase 0.0051 0.014 0.014
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0104 0.0155
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.2895
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.009 0.0247
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0018 0.0017
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0016 0.0051
Onchocerca volvulus 0.0165 0.0604 0.0909
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0134 0.0479 0.0478
Loa Loa (eye worm) blistered cuticle protein 3 0.013 0.0464 0.0463
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0197 0.0737 0.0737
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0119 0.0119
Chlamydia trachomatis glycogen phosphorylase 0.0119 0.0415 0.5
Onchocerca volvulus Peroxidasin homolog 0.013 0.0464 0.0698
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0181 0.018
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0197 0.0737 0.2424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Echinococcus multilocularis calpain A 0.2052 0.8335 0.8335
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0092 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0531 0.2103 0.2103
Plasmodium falciparum plasmepsin IV 0.003 0.0053 0.0172
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0134 0.0479 0.0478
Onchocerca volvulus 0.0758 0.3035 0.4568
Plasmodium vivax serine-repeat antigen (SERA) 0.0197 0.0737 0.2424
Plasmodium falciparum centrin-1 0.0117 0.041 0.135
Schistosoma mansoni glycogen phosphorylase 0.0119 0.0415 0.0415
Onchocerca volvulus 0.0758 0.3035 0.4568
Onchocerca volvulus 0.0168 0.0618 0.0931
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0456 0.0456
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0046 0.0119 0.0119
Loa Loa (eye worm) peptidase family M13 containing protein 0.0068 0.0207 0.0206
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Echinococcus granulosus microtubule associated protein 2 0.1453 0.5881 0.588
Loa Loa (eye worm) hypothetical protein 0.0117 0.041 0.041
Schistosoma mansoni hypothetical protein 0.0168 0.0618 0.0618
Schistosoma mansoni ap endonuclease 0.0039 0.009 0.009
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0197 0.0737 0.1108
Brugia malayi Eukaryotic aspartyl protease family protein 0.003 0.0053 0.0052
Echinococcus multilocularis neuronal calcium sensor 0.0117 0.041 0.041
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Brugia malayi Cathepsin L-like precursor 0.0758 0.3035 0.3034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0315 0.0315
Schistosoma mansoni cpg binding protein 0.0031 0.0058 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1639 0.6644 0.6644
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0315 0.0315
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0737 0.0737
Echinococcus multilocularis cathepsin b 0.2459 1 1
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Giardia lamblia Encystation-specific protease 0.0197 0.0737 0.2043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0531 0.2103 0.5839
Echinococcus multilocularis programmed cell death protein 0.0121 0.0425 0.0424
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.4357
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0737 0.2043
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0037 0.0055
Onchocerca volvulus 0.0758 0.3035 0.4568
Plasmodium falciparum plasmepsin IX 0.0109 0.0377 0.124
Loa Loa (eye worm) calpain 0.0724 0.2895 0.2895
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0186 0.0279
Schistosoma mansoni hypothetical protein 0.0045 0.0115 0.0115
Schistosoma mansoni mitochondrial solute carrier 0.0117 0.041 0.041
Trypanosoma cruzi centrin, putative 0.0121 0.0425 0.0424
Echinococcus multilocularis calbindin 32 0.0119 0.0419 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0018 0.0017
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0134 0.0479 0.0478
Plasmodium falciparum calpain 0.0212 0.0799 0.2629
Schistosoma mansoni cathepsin D (A01 family) 0.0122 0.0432 0.0432
Mycobacterium leprae Conserved hypothetical protein 0.0174 0.0643 0.2407
Trichomonas vaginalis centrin, putative 0.0117 0.041 0.1137
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0015
Plasmodium falciparum flap endonuclease 1 0.0026 0.0037 0.012
Toxoplasma gondii cathepsin CPL 0.0758 0.3035 0.4568
Giardia lamblia Cysteine protease 0.0197 0.0737 0.2043
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0288 0.1109 0.1109
Trypanosoma brucei oligopeptidase b 0.0669 0.2669 0.4017
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0018 0.0017
Echinococcus multilocularis calpain 7 (C02 family) 0.0724 0.2895 0.2895
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0168 0.0618 0.0617
Schistosoma mansoni cathepsin F (C01 family) 0.0531 0.2103 0.2103
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0104 0.034
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0117 0.041 0.1137
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Trichomonas vaginalis calpain, putative 0.0212 0.0799 0.2215
Onchocerca volvulus 0.0094 0.0315 0.0474
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0315 0.0472
Schistosoma mansoni hypothetical protein 0.0134 0.0479 0.0479
Onchocerca volvulus Glycogen phosphorylase homolog 0.0119 0.0415 0.0625
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0424 0.1668 0.1668
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0099 0.0098
Brugia malayi programmed cell death protein 6 0.0117 0.041 0.041
Brugia malayi cathepsin L-like precursor 0.0531 0.2103 0.2103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0015
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0139 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0018 0.0017
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.005 0.0049
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0292 0.0291
Loa Loa (eye worm) hypothetical protein 0.0165 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0143 0.0142
Schistosoma mansoni calpain (C02 family) 0.0724 0.2895 0.2895
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0456 0.0456
Leishmania major kinesin, putative 0.0512 0.2027 0.305
Loa Loa (eye worm) cysteine protease 0.0758 0.3035 0.3034
Onchocerca volvulus 0.0029 0.005 0.0075
Plasmodium vivax proteasome subunit beta type-5, putative 0.0088 0.0292 0.0958
Loa Loa (eye worm) hypothetical protein 0.0228 0.0862 0.0861
Brugia malayi fibroinase precursor 0.0197 0.0737 0.0736
Brugia malayi MH2 domain containing protein 0.0125 0.0443 0.0442
Brugia malayi Animal haem peroxidase family protein 0.013 0.0464 0.0463
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0018 0.0017
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0104 0.0103
Schistosoma mansoni hypothetical protein 0.0175 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Onchocerca volvulus 0.0029 0.005 0.0075
Onchocerca volvulus Chorion peroxidase homolog 0.013 0.0464 0.0698
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0018 0.0018
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0099 0.0098
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.005 0.0049
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.2895
Plasmodium vivax hypothetical protein, conserved 0.0119 0.0419 0.1378
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0018 0.0018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0018 0.0027
Loa Loa (eye worm) cathepsin B 0.0896 0.3602 0.3601
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Echinococcus multilocularis microtubule associated protein 2 0.1453 0.5881 0.588
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0211 0.021
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0197 0.0737 0.2044
Echinococcus granulosus calpain A 0.2052 0.8335 0.8335
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0212 0.0799 0.0798
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0212 0.0799 0.0798
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0669 0.2669 0.2668
Brugia malayi Flap endonuclease-1 0.0026 0.0037 0.0036
Onchocerca volvulus 0.0029 0.005 0.0075
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0737 0.2043
Mycobacterium tuberculosis Conserved protein 0.0174 0.0643 0.11
Echinococcus granulosus prolyl endopeptidase 0.1639 0.6644 0.6644
Plasmodium vivax aspartyl protease, putative 0.0109 0.0377 0.124
Brugia malayi prolyl oligopeptidase family protein 0.0197 0.0737 0.0736
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0098
Echinococcus multilocularis cathepsin b 0.2459 1 1
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0117 0.041 0.1137
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.009 0.0247
Loa Loa (eye worm) hypothetical protein 0.0069 0.0214 0.0213
Brugia malayi calcium-binding protein 0.0117 0.041 0.041
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0037 0.012
Brugia malayi nuclear receptor NHR-88 0.0022 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Toxoplasma gondii microneme protein MIC17A 0.0029 0.005 0.0073
Schistosoma mansoni endothelin-converting enzyme-related 0.0022 0.0021 0.0021
Entamoeba histolytica prolyl oligopeptidase family protein 0.0197 0.0737 0.2426
Schistosoma mansoni reticulocalbin 0.0117 0.041 0.041
Giardia lamblia Cathepsin L-like protease 0.0197 0.0737 0.2043
Trichomonas vaginalis conserved hypothetical protein 0.0212 0.0799 0.2215
Brugia malayi PXA domain containing protein 0.0041 0.0099 0.0098
Brugia malayi Trypsin family protein 0.0168 0.0618 0.0617
Trypanosoma cruzi major cysteine proteinase, putative 0.0197 0.0737 0.0736
Plasmodium vivax serine-repeat antigen (SERA) 0.0197 0.0737 0.2424
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.0115 0.0114
Trichomonas vaginalis calmodulin, putative 0.0121 0.0425 0.1177
Entamoeba histolytica calcium binding family protein 0.0117 0.041 0.135
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Schistosoma mansoni memapsin-2 (A01 family) 0.0481 0.1898 0.1898
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0043
Echinococcus multilocularis calpain 5 0.0724 0.2895 0.2895
Plasmodium vivax centrin-1, putative 0.0117 0.041 0.135
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0669 0.2669 0.4017
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0464 0.0463
Onchocerca volvulus Peroxidase homolog 0.013 0.0464 0.0698
Plasmodium vivax calpain, putative 0.0724 0.2895 0.954
Onchocerca volvulus 0.0029 0.005 0.0075
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Entamoeba histolytica cysteine protease, putative 0.0197 0.0737 0.2424
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2459 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0212 0.0799 0.0798
Schistosoma mansoni hypothetical protein 0.0174 0.0643 0.0643
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0215 0.0215
Brugia malayi Pre-SET motif family protein 0.0094 0.0315 0.0314
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.003 0.0053 0.0145
Loa Loa (eye worm) hypothetical protein 0.0068 0.0207 0.0206
Loa Loa (eye worm) ctsf protein 0.0758 0.3035 0.3034
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Echinococcus granulosus cysteine protease 0.0424 0.1668 0.1668
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0037 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0197 0.0737 0.2043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0018 0.0017
Brugia malayi Animal haem peroxidase family protein 0.013 0.0464 0.0463
Onchocerca volvulus 0.0045 0.0115 0.0173
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0197 0.0737 0.2424
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0104 0.0286
Schistosoma mansoni neuronal calcium sensor 0.0117 0.041 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0197 0.0737 0.2043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0018 0.0017
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0017 0.0001 0.0001
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0212 0.0799 0.0798
Mycobacterium ulcerans hypothetical protein 0.0168 0.0618 0.2314
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0018 0.0017
Leishmania major cathepsin L-like protease 0.0758 0.3035 0.4568
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0134 0.0479 0.0478
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Onchocerca volvulus 0.0054 0.0151 0.0227
Leishmania major calcineurin B subunit, putative 0.0117 0.041 0.0616
Toxoplasma gondii microneme protein MIC17B 0.0029 0.005 0.0073
Plasmodium falciparum serine repeat antigen 6 0.0197 0.0737 0.2424
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1639 0.6644 0.6644
Schistosoma mansoni cathepsin F (C01 family) 0.0758 0.3035 0.3035
Toxoplasma gondii calmodulin CAM1 0.0119 0.0419 0.0629
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.009 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0099 0.0099
Brugia malayi Cathepsin L-like precursor 0.0758 0.3035 0.3034
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0104 0.0103
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0151 0.0151
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0168 0.0618 0.0617
Giardia lamblia Transglutaminase/protease, putative 0.0174 0.0643 0.1784
Trypanosoma cruzi cysteine peptidase, putative 0.086 0.345 0.345
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0104 0.0155
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Entamoeba histolytica glycogen phosphorylase, putative 0.0119 0.0415 0.1366
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0197 0.0737 0.2424
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0197 0.0737 0.0736
Entamoeba histolytica hypothetical protein 0.0041 0.0099 0.0323
Echinococcus multilocularis cysteine protease 0.0758 0.3035 0.3034
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0212 0.0799 0.2215
Loa Loa (eye worm) CYP4Cod1 0.0034 0.007 0.0069
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0724 0.2895 0.2895
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0211 0.0692
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0211 0.0583
Toxoplasma gondii microneme protein MIC17C 0.0029 0.005 0.0073
Plasmodium falciparum serine repeat antigen 1 0.0197 0.0737 0.2424
Loa Loa (eye worm) programmed cell death protein 6 0.0119 0.0419 0.0418
Loa Loa (eye worm) hypothetical protein 0.1421 0.5749 0.5748
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Schistosoma mansoni centrin 0.0117 0.041 0.041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0724 0.2895 0.2895
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.009 0.0089
Giardia lamblia Cathepsin L-like protease 0.0197 0.0737 0.2043
Brugia malayi Cathepsin L-like precursor 0.0758 0.3035 0.3034
Schistosoma mansoni ap endonuclease 0.0039 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0069 0.0214 0.0213
Plasmodium vivax plasmepsin V, putative 0.003 0.0053 0.0172
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0464 0.0463
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0099 0.0098
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0117 0.041 0.041
Mycobacterium tuberculosis Hypothetical protein 0.0174 0.0643 0.11
Plasmodium falciparum serine repeat antigen 3 0.0197 0.0737 0.2424
Echinococcus granulosus flap endonuclease 1 0.0026 0.0037 0.0036
Schistosoma mansoni Mername-AA248 (C02 family) 0.0724 0.2895 0.2895
Leishmania major cytochrome p450-like protein 0.0034 0.007 0.0103
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0212 0.0799 0.2215
Brugia malayi Protein kinase domain containing protein 0.0045 0.0115 0.0114
Onchocerca volvulus 0.0031 0.0058 0.0087
Trichomonas vaginalis calmodulin, putative 0.0117 0.041 0.1137
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0197 0.0737 0.2424
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.014 0.0457
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0021 0.0016 0.0051
Echinococcus granulosus Dipeptidyl peptidase 9 0.0288 0.1109 0.1109
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0104 0.0286
Giardia lamblia Cathepsin B precursor 0.0896 0.3602 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0018 0.0017
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0099 0.0098
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0117 0.041 0.041
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0115 0.0114
Entamoeba histolytica prolyl oligopeptidase family protein 0.0197 0.0737 0.2426
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0211 0.0583
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0099 0.0098
Brugia malayi steroid hormone receptor 0.0022 0.0018 0.0017
Onchocerca volvulus 0.0052 0.0143 0.0215
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Echinococcus granulosus EF hand domain containing family member A2 0.0119 0.0419 0.0418
Trypanosoma cruzi caltractin, putative 0.0117 0.041 0.041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Mycobacterium tuberculosis Probable peptidase 0.0669 0.2669 0.4572
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0104 0.0103
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.009 0.0089
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Giardia lamblia Cathepsin B precursor 0.0896 0.3602 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0018 0.0017
Echinococcus multilocularis tumor protein p63 0.0368 0.1438 0.1437
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0037 0.0101
Echinococcus multilocularis geminin 0.0175 0.0646 0.0645
Plasmodium vivax aspartyl proteinase, putative 0.003 0.0053 0.0172
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0211 0.021
Echinococcus multilocularis caspase 2 0.0061 0.0181 0.018
Entamoeba histolytica hypothetical protein, conserved 0.0119 0.0419 0.1378
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0099 0.0272
Toxoplasma gondii microneme protein MIC4 0.0029 0.005 0.0073
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.0456 0.0455
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Brugia malayi calpain family protein 1 0.1933 0.7846 0.7845
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0758 0.3035 0.3034
Plasmodium vivax vivapain-2 0.0758 0.3035 1
Trypanosoma cruzi oligopeptidase b 0.0669 0.2669 0.2668
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0119 0.0419 0.0419
Trypanosoma brucei calpain-like protein, putative 0.0724 0.2895 0.4357
Giardia lamblia Cathepsin B precursor 0.0197 0.0737 0.2043
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0212 0.0799 0.0798
Plasmodium vivax aspartyl protease, putative 0.003 0.0053 0.0172
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0197 0.0737 0.2043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Brugia malayi calpain 7 0.0724 0.2895 0.2895
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.0456 0.078
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0288 0.1109 0.1669
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0021 0.0016 0.0043
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0018 0.0017
Plasmodium vivax unspecified product 0.0197 0.0737 0.2424
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Trypanosoma brucei calmodulin, putative 0.0119 0.0419 0.0629
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0018 0.0017
Toxoplasma gondii cathepsin CPC2 0.0197 0.0737 0.1107
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Onchocerca volvulus 0.0029 0.005 0.0075
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0017 0.0001 0.0001
Trypanosoma cruzi I/6 autoantigen, putative 0.0117 0.041 0.041
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0197 0.0737 0.0737
Brugia malayi Cathepsin L-like precursor 0.0758 0.3035 0.3034
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0443 0.0442
Onchocerca volvulus 0.003 0.0053 0.008
Echinococcus granulosus EF HAND 1 calcium binding site 0.0117 0.041 0.041
Onchocerca volvulus 0.0168 0.0618 0.0931
Onchocerca volvulus 0.0029 0.005 0.0075
Echinococcus multilocularis cathepsin L 0.0424 0.1668 0.1668
Brugia malayi Trypsin family protein 0.0168 0.0618 0.0617
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0425 0.1177
Toxoplasma gondii troponin c, isotype gamma, putative 0.0117 0.041 0.0616
Loa Loa (eye worm) hypothetical protein 0.0094 0.0315 0.0314
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0021 0.0016 0.0015
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Onchocerca volvulus 0.0741 0.2966 0.4464
Leishmania major cathepsin L-like protease 0.086 0.345 0.5192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Loa Loa (eye worm) animal heme peroxidase 0.013 0.0464 0.0463
Echinococcus granulosus cathepsin l1 0.0531 0.2103 0.2103
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0104 0.0103
Schistosoma mansoni hypothetical protein 0.0061 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Onchocerca volvulus 0.0168 0.0618 0.0931
Toxoplasma gondii hypothetical protein 0.0212 0.0799 0.1201
Trichomonas vaginalis peptide N-glycanase, putative 0.0174 0.0643 0.1784
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0737 0.2043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Echinococcus multilocularis calcium uptake protein 1 0.0119 0.0419 0.0418
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0211 0.0692
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.4357
Loa Loa (eye worm) calpain family protein 1 0.1933 0.7846 0.7845
Leishmania major hypothetical protein, conserved 0.0117 0.041 0.0616
Leishmania major cathepsin L-like protease 0.0758 0.3035 0.4568
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0052
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Echinococcus granulosus calumenin 0.0119 0.0419 0.0418
Leishmania major centrin, putative 0.0117 0.041 0.0616
Plasmodium falciparum plasmepsin I 0.003 0.0053 0.0172
Trypanosoma brucei hypothetical protein 0.0212 0.0799 0.1201
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Trichomonas vaginalis set domain proteins, putative 0.0741 0.2965 0.8232
Toxoplasma gondii PAN domain-containing protein 0.0029 0.005 0.0073
Brugia malayi cathepsin L precursor 0.0197 0.0737 0.0736
Brugia malayi CXXC zinc finger family protein 0.0031 0.0058 0.0057
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0424 0.1668 0.1668
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0018 0.0017
Echinococcus granulosus calpain 7 C02 family 0.0724 0.2895 0.2895
Plasmodium falciparum peptidase, putative 0.0197 0.0737 0.2426
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0212 0.0799 0.0798
Leishmania major calpain family cysteine protease-like protein 0.0212 0.0799 0.1201
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0139 0.0138
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0088 0.0292 0.0498
Echinococcus granulosus glycogen phosphorylase 0.0119 0.0415 0.0414
Entamoeba histolytica hypothetical protein 0.0041 0.0099 0.0323
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0393 0.1538 0.1537
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0212 0.0799 0.2215
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0088 0.0292 0.109
Schistosoma mansoni survival motor neuron protein 0.0052 0.0143 0.0143
Echinococcus multilocularis cathepsin L 0.0197 0.0737 0.0736
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0028 0.0028
Trypanosoma cruzi I/6 autoantigen, putative 0.0117 0.041 0.041
Loa Loa (eye worm) calpain 5 0.0512 0.2027 0.2026
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0099 0.0098
Trypanosoma brucei calpain, putative 0.0212 0.0799 0.1201
Echinococcus granulosus survival motor neuron protein 1 0.0255 0.0972 0.0971
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0724 0.2895 0.2895
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Schistosoma mansoni hypothetical protein 0.0117 0.041 0.041
Echinococcus multilocularis cathepsin L cysteine protease 0.0758 0.3035 0.3034
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Entamoeba histolytica cysteine proteinase, putative 0.0424 0.1668 0.5496
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0021 0.0021
Trypanosoma brucei Aph-1 protein, putative 0.0097 0.0329 0.0494
Entamoeba histolytica cysteine protease, putative 0.0197 0.0737 0.2424
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0758 0.3035 0.8427
Trichomonas vaginalis centrin, putative 0.0117 0.041 0.1137
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0018 0.0027
Plasmodium falciparum serine repeat antigen 9 0.0197 0.0737 0.2424
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Giardia lamblia Cathepsin B precursor 0.0197 0.0737 0.2043
Loa Loa (eye worm) prolyl oligopeptidase 0.0197 0.0737 0.0736
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0212 0.0799 0.1201
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0104 0.0286
Onchocerca volvulus Cathepsin L homolog 0.0197 0.0737 0.1109
Onchocerca volvulus Cathepsin F homolog 0.0758 0.3035 0.4568
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0099 0.0098
Echinococcus granulosus geminin 0.0175 0.0646 0.0645
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.205 0.8326 0.8326
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0197 0.0737 0.2424
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0051 0.014 0.0238
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0456 0.1707
Leishmania major proteasome beta 5 subunit, putative 0.0088 0.0292 0.0438
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0021 0.0016 0.0043
Leishmania major cysteine peptidase A (CPA) 0.0758 0.3035 0.4568
Echinococcus granulosus calbindin 32 0.0119 0.0419 0.0418
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0099 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0139 0.0139
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0018 0.0017
Trypanosoma brucei calmodulin, putative 0.0117 0.041 0.0616
Loa Loa (eye worm) hypothetical protein 0.0168 0.0618 0.0617
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Echinococcus multilocularis prolyl endopeptidase 0.1639 0.6644 0.6644
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0099 0.0098
Loa Loa (eye worm) calmodulin-like protein 0.0117 0.041 0.041
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0523 0.2072 0.2072
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0197 0.0737 0.2426
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0197 0.0737 0.2043
Echinococcus multilocularis centrin 2 0.0117 0.041 0.041
Mycobacterium ulcerans proteasome PrcB 0.0088 0.0292 0.109
Trypanosoma brucei antigen, putative 0.0724 0.2895 0.4357
Trypanosoma brucei cytochrome P450, putative 0.0034 0.007 0.0103
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0197 0.0737 0.0736
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0737 0.0737
Schistosoma mansoni calmodulin 0.0117 0.041 0.041
Echinococcus multilocularis calmodulin 0.0117 0.041 0.041
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0117 0.041 0.041
Entamoeba histolytica grainin, putative 0.0119 0.0419 0.1378
Loa Loa (eye worm) hypothetical protein 0.0197 0.0737 0.0736
Loa Loa (eye worm) hypothetical protein 0.0054 0.0151 0.015
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0197 0.0737 0.2424
Leishmania major centrin, putative 0.0117 0.041 0.0616
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.0798
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0115 0.0114
Entamoeba histolytica hypothetical protein 0.0041 0.0099 0.0323
Toxoplasma gondii PAN domain-containing protein 0.0029 0.005 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0758 0.3035 0.8427
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0288 0.1109 0.1669
Brugia malayi hypothetical protein 0.0255 0.0972 0.0971
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.013 0.0464 0.0463
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0058 0.0057
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0022 0.0021 0.0021
Trypanosoma cruzi cysteine proteinase, putative 0.0424 0.1668 0.1668
Echinococcus granulosus neuronal calcium sensor 0.0117 0.041 0.041
Toxoplasma gondii centrin, putative 0.0117 0.041 0.0616
Brugia malayi hypothetical protein 0.0168 0.0618 0.0617
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Brugia malayi Blistered cuticle protein 3 0.013 0.0464 0.0463
Echinococcus multilocularis glycogen phosphorylase 0.0119 0.0415 0.0414
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0168 0.0618 0.0617
Entamoeba histolytica cysteine protease, putative 0.0424 0.1668 0.5496
Giardia lamblia Hypothetical protein 0.0174 0.0643 0.1784
Brugia malayi proteasome subunit beta type 1 0.0069 0.0211 0.021
Loa Loa (eye worm) hypothetical protein 0.1721 0.6977 0.6977
Echinococcus multilocularis enteropeptidase 0.0168 0.0618 0.0617
Echinococcus multilocularis gamma secretase subunit aph 1 0.025 0.0954 0.0953
Brugia malayi Cytochrome P450 family protein 0.0034 0.007 0.0069
Plasmodium falciparum cysteine proteinase falcipain 1 0.0424 0.1668 0.5496
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0099 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0737 0.2043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Leishmania major calmodulin-like protein 0.0117 0.041 0.0616
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0088 0.0292 0.0292
Onchocerca volvulus 0.0022 0.0018 0.0027
Onchocerca volvulus Cathepsin L homolog 0.0758 0.3035 0.4568
Echinococcus granulosus gamma secretase subunit aph 1 0.025 0.0954 0.0953
Brugia malayi PAN domain containing protein 0.0029 0.005 0.0049
Plasmodium falciparum serine repeat antigen 8 0.0197 0.0737 0.2424
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0896 0.3602 0.542
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0049
Echinococcus granulosus glycogen phosphorylase 0.0119 0.0415 0.0414
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Echinococcus granulosus cathepsin b 0.2459 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0099 0.0098
Entamoeba histolytica calpain family cysteine protease, putative 0.0212 0.0799 0.2629
Echinococcus granulosus cathepsin l1 0.0758 0.3035 0.3034
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0197 0.0737 0.2043
Echinococcus granulosus centrin 2 0.0117 0.041 0.041
Brugia malayi cathepsin Z-like cysteine proteinase 0.0197 0.0737 0.0736
Onchocerca volvulus 0.0117 0.041 0.0618
Echinococcus multilocularis survival motor neuron protein 1 0.0255 0.0972 0.0971
Leishmania major protein kinase, putative 0.0117 0.041 0.0616
Schistosoma mansoni cathepsin C 0.0197 0.0737 0.0737
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0099 0.0099
Trypanosoma cruzi prolyl endopeptidase 0.1639 0.6644 0.6644
Echinococcus granulosus calmodulin 0.0117 0.041 0.041
Toxoplasma gondii EFHC1, putative 0.0117 0.041 0.0616
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0134 0.0479 0.0479
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2459 1 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0197 0.0737 0.2424
Schistosoma mansoni hypothetical protein 0.0117 0.041 0.041
Entamoeba histolytica cysteine proteinase 2 0.0424 0.1668 0.5496
Leishmania major cathepsin L-like protease 0.086 0.345 0.5192
Trichomonas vaginalis calcium binding protein, putative 0.0117 0.041 0.1137
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0523 0.2072 0.2071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0018 0.0017
Leishmania major calmodulin-like protein 0.0117 0.041 0.0616
Loa Loa (eye worm) hypothetical protein 0.0228 0.0862 0.0861
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0896 0.3602 0.3602
Brugia malayi ecdysteroid receptor 0.0022 0.0018 0.0017
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0315 0.0314
Brugia malayi EF hand family protein 0.0117 0.041 0.041
Schistosoma mansoni reticulocalbin 0.0119 0.0419 0.0419
Trichomonas vaginalis calcineurin B subunit, putative 0.0117 0.041 0.1137
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0212 0.0799 0.2215
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0021 0.0016 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0197 0.0737 0.0736
Mycobacterium ulcerans hypothetical protein 0.0174 0.0643 0.2407
Trypanosoma cruzi cysteine peptidase, putative 0.0758 0.3035 0.3034
Schistosoma mansoni hypothetical protein 0.0445 0.1753 0.1753
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0393 0.1538 0.1537
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0288 0.1109 0.1669
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0212 0.0799 0.0798
Trypanosoma cruzi conserved protein 0.0212 0.0799 0.0798
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0211 0.0316
Echinococcus granulosus peroxidasin 0.013 0.0464 0.0463
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0018 0.0018
Toxoplasma gondii peptidase family M13 protein 0.0092 0.0305 0.0458
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0197 0.0737 0.2043
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.003 0.0053 0.0078
Entamoeba histolytica cysteine protease, putative 0.0197 0.0737 0.2424
Schistosoma mansoni cathepsin F (C01 family) 0.0758 0.3035 0.3035
Trypanosoma cruzi cysteine peptidase, putative 0.086 0.345 0.345
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Echinococcus multilocularis glycoprotein Antigen 5 0.0168 0.0618 0.0617
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0018 0.0017
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.025 0.0954 0.0953
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.3035 0.8427
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0099 0.0098
Echinococcus granulosus calpain A 0.0724 0.2895 0.2895
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0139 0.0139
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0212 0.0799 0.1201
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0068 0.0207 0.0206
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0017 0.0001 0.0001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0724 0.2895 0.2895
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0168 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Echinococcus multilocularis calumenin 0.0119 0.0419 0.0418
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.007 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0424 0.1668 0.4631
Onchocerca volvulus 0.0168 0.0618 0.0931
Giardia lamblia Hypothetical protein 0.0119 0.0419 0.1161
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0021 0.0016 0.0043
Giardia lamblia Cathepsin B precursor 0.0896 0.3602 1
Schistosoma mansoni hypothetical protein 0.0024 0.0028 0.0028
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0117 0.041 0.041
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0197 0.0737 0.0736
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0017 0.0001 0.0001
Loa Loa (eye worm) fibroinase 0.0758 0.3035 0.3034
Toxoplasma gondii preprocathepsin c precursor, putative 0.0197 0.0737 0.1107
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0018 0.0017
Echinococcus granulosus dnaJ subfamily B 0.0445 0.1753 0.1752
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0758 0.3035 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0092 0.0305 0.0304
Trypanosoma brucei mitochondrial calcium uptake 1 0.0117 0.041 0.0616
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0669 0.2669 0.2668
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.003 0.0053 0.0053
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0212 0.0799 0.0798
Trypanosoma brucei Calpain-like protein 1.1 0.0212 0.0799 0.1201
Trichomonas vaginalis calmodulin-2, putative 0.0117 0.041 0.1137
Entamoeba histolytica cysteine proteinase, putative 0.0758 0.3035 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.009 0.0334
Toxoplasma gondii subtilisin SUB12 0.0029 0.005 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Trypanosoma brucei Component of motile flagella 41 0.0117 0.041 0.0616
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Onchocerca volvulus 0.0021 0.0016 0.0025
Brugia malayi aspartic protease BmAsp-1, identical 0.003 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0134 0.0479 0.0478
Echinococcus multilocularis calmodulin 0.0117 0.041 0.041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0456 0.1707
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0651 0.2597 0.2596
Trypanosoma cruzi centrin-3 0.0121 0.0425 0.0424
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.003 0.0053 0.0052
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Loa Loa (eye worm) hypothetical protein 0.0069 0.0214 0.0213
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.014 0.0457
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0046 0.0119 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0018 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0737 0.2043
Schistosoma mansoni neuronal calcium sensor 0.0117 0.041 0.041
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0021 0.0016 0.0023
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0758 0.3035 0.3034
Brugia malayi Pre-SET motif family protein 0.0651 0.2597 0.2596
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0018 0.0017
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0099 0.0098
Schistosoma mansoni calpain-2 (C02 family) 0.0212 0.0799 0.0799
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0212 0.0799 0.1201
Brugia malayi cathepsin F-like cysteine proteinase 0.0197 0.0737 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0737 0.2043
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.0115 0.0375
Brugia malayi calpain 5 0.0512 0.2027 0.2026
Echinococcus multilocularis Mastin 0.0168 0.0618 0.0617
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0181 0.018
Leishmania major oligopeptidase b 0.0669 0.2669 0.4017
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0099 0.0099
Onchocerca volvulus 0.0117 0.041 0.0618
Schistosoma mansoni rab 0.0117 0.041 0.041
Schistosoma mansoni cpg binding protein 0.0033 0.0065 0.0065
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0022 0.0021 0.0021
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0211 0.0316
Echinococcus granulosus inhibitor of apoptosis protein 0.0134 0.0479 0.0478
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2459 1 1
Onchocerca volvulus 0.0134 0.0479 0.0721
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.009 0.0134
Trypanosoma brucei calpain-like protein, putative 0.0724 0.2895 0.4357
Toxoplasma gondii PAN domain-containing protein 0.0029 0.005 0.0073
Brugia malayi peptidase family M13 containing protein 0.0022 0.0021 0.002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0315 0.0314
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.4357
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0758 0.3035 0.3034
Schistosoma mansoni cercarial elastase (S01 family) 0.0168 0.0618 0.0618
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0315 0.0314
Mycobacterium ulcerans transglutaminase family protein 0.0174 0.0643 0.2407
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0099 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0018 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.086 0.345 0.5192
Trypanosoma brucei protein I/6 0.0117 0.041 0.0616
Schistosoma mansoni hypothetical protein 0.0052 0.0143 0.0143
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0092 0.0305 0.0304
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0724 0.2895 0.4357
Echinococcus multilocularis Transglutaminase 0.0174 0.0643 0.0642
Leishmania major cathepsin L-like protease 0.0758 0.3035 0.4568
Trichomonas vaginalis glycogen phosphorylase, putative 0.0119 0.0415 0.1151
Echinococcus multilocularis Glycosyl transferase, family 35 0.0119 0.0415 0.0414
Brugia malayi Cell death protein 3 precursor 0.0061 0.0181 0.018
Trypanosoma brucei Calpain-like protein 1.2 0.0212 0.0799 0.1201
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0117 0.041 0.0616
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0197 0.0737 0.2424
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0037 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.041 0.1137
Trichomonas vaginalis calpain, putative 0.0212 0.0799 0.2215
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0021 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0052
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0181 0.0181
Brugia malayi hypothetical protein 0.003 0.0053 0.0052
Brugia malayi hypothetical protein 0.0165 0.0604 0.0603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0139 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.041 0.1137
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0099 0.0099
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0197 0.0737 0.0737
Onchocerca volvulus 0.0758 0.3035 0.4568
Loa Loa (eye worm) hypothetical protein 0.0117 0.041 0.041

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.06 nM Inhibition of human neutrophil elastase ChEMBL. 18053726
Ki (binding) = 0.06 nM Inhibition of human neutrophil elastase ChEMBL. 18053726

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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