Detailed information for compound 52759

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 571.516 | Formula: C28H41Cl2N2O4P
  • H donors: 2 H acceptors: 3 LogP: 6.87 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: ClCCN(P1(=O)OCCCN1CCCC[C@@H]([C@](c1ccc(cc1)O)(CC)C)c1ccc(cc1)O)CCCl
  • InChi: 1S/C28H41Cl2N2O4P/c1-3-28(2,24-10-14-26(34)15-11-24)27(23-8-12-25(33)13-9-23)7-4-5-18-31-19-6-22-36-37(31,35)32(20-16-29)21-17-30/h8-15,27,33-34H,3-7,16-22H2,1-2H3/t27-,28+,37?/m1/s1
  • InChiKey: XKZCMKCFCJOIAZ-XXAOTXJLSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0043 0.0043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1091 0.2829 0.2829
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0197 0.0197
Schistosoma mansoni caspase-7 (C14 family) 0.0364 0.0899 0.0899
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0055 0.0077 0.0077
Echinococcus multilocularis neurogenic locus notch protein 0.0045 0.005 0.005
Toxoplasma gondii peptidase family M13 protein 0.0096 0.0187 0.0355
Brugia malayi Eukaryotic aspartyl protease family protein 0.0055 0.0077 0.0077
Brugia malayi prolyl oligopeptidase family protein 0.0331 0.0809 0.0809
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0063 0.0148
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0307 0.0746 0.2398
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0317 0.0773 0.2121
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Brugia malayi Papain family cysteine protease containing protein 0.1186 0.308 0.308
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.1093 0.1093
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Toxoplasma gondii calcium-dependent protein kinase 0.0166 0.0372 0.0705
Echinococcus granulosus neurogenic locus protein delta 0.0045 0.005 0.005
Trypanosoma brucei hypothetical protein, conserved 0.011 0.0222 0.0422
Plasmodium falciparum serine repeat antigen 8 0.0307 0.0746 0.2398
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0136 0.0293 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Echinococcus multilocularis prolyl endopeptidase 0.2012 0.5275 0.5275
Leishmania major cathepsin L-like protease 0.1289 0.3353 0.6357
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0307 0.0746 0.2398
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0044 0.0044
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0818 0.2102 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3083 0.8118 0.8118
Brugia malayi Cathepsin L-like precursor 0.0829 0.2134 0.2134
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0056 0.0151
Leishmania major centrin, putative 0.0163 0.0365 0.0692
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.011 0.0222 0.0222
Echinococcus granulosus glycoprotein Antigen 5 0.0196 0.0451 0.0451
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0151 0.0332 0.0332
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0196 0.0451 0.0451
Schistosoma mansoni lamin 0.0054 0.0075 0.0075
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0151 0.0332 0.0896
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0044 0.0044
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0053 0.0143
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0075 0.013 0.0334
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.2603 0.6843 0.6843
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0818 0.2102 0.3986
Trypanosoma brucei calmodulin, putative 0.0165 0.0371 0.0702
Mycobacterium tuberculosis Conserved hypothetical protein 0.0318 0.0775 0.1668
Leishmania major hypothetical protein, conserved 0.011 0.0222 0.0422
Onchocerca volvulus 0.1828 0.4786 0.9072
Loa Loa (eye worm) transcriptional regulator 0.0035 0.0024 0.0024
Giardia lamblia Cathepsin L precursor 0.0307 0.0746 0.2046
Schistosoma mansoni hypothetical protein 0.0163 0.0365 0.0365
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1775 0.4646 1
Plasmodium vivax SET domain protein, putative 0.01 0.0197 0.061
Entamoeba histolytica calpain large subunit domain III containing protein 0.0774 0.1988 0.6443
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Brugia malayi Protein kinase domain containing protein 0.0046 0.0053 0.0053
Loa Loa (eye worm) calpain 0.1091 0.2829 0.2829
Onchocerca volvulus 0.0045 0.005 0.0075
Trichomonas vaginalis calcium binding protein, putative 0.0163 0.0365 0.0988
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0317 0.0773 0.1465
Echinococcus multilocularis neural cadherin 0.0045 0.005 0.005
Brugia malayi mbt repeat family protein 0.0048 0.0058 0.0058
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Trichomonas vaginalis hypothetical protein 0.0317 0.0773 0.2121
Brugia malayi Blistered cuticle protein 3 0.0507 0.1279 0.1279
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0043 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0222 0.0592
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0307 0.0746 0.2398
Schistosoma mansoni ets-related 0.0446 0.1115 0.1115
Toxoplasma gondii PAN domain-containing protein 0.003 0.001 0.0019
Loa Loa (eye worm) sirtuin 4 0.0035 0.0024 0.0024
Brugia malayi cathepsin L-like cysteine proteinase 0.0307 0.0746 0.0746
Trichomonas vaginalis calpain, putative 0.0317 0.0773 0.2121
Plasmodium falciparum metacaspase 1 0.0149 0.0326 0.103
Echinococcus granulosus apoptotic protease activating factor 1 0.0216 0.0504 0.0504
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Trypanosoma cruzi oligopeptidase b 0.0818 0.2102 0.2102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Schistosoma mansoni laminin gamma-3 chain 0.0045 0.005 0.005
Schistosoma mansoni chromatin regulatory protein sir2 0.0151 0.0332 0.0332
Plasmodium falciparum serine repeat antigen 5 0.0307 0.0746 0.2398
Echinococcus multilocularis cathepsin L cysteine protease 0.1186 0.308 0.308
Trypanosoma brucei proteasome beta 6 subunit 0.0075 0.013 0.0246
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Schistosoma mansoni hypothetical protein 0.0437 0.1093 0.1093
Trypanosoma cruzi histone deacetylase 1, putative 0.0085 0.0157 0.0157
Schistosoma mansoni notch 0.0045 0.005 0.005
Echinococcus multilocularis calcium uptake protein 1 0.0165 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0829 0.2134 0.2134
Echinococcus granulosus protein jagged 1 0.0045 0.005 0.005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Leishmania major cathepsin L-like protease 0.1186 0.308 0.5839
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0084 0.016
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1091 0.2829 0.5364
Echinococcus multilocularis serotonin receptor 0.0154 0.034 0.034
Leishmania major histone deacetylase, putative 0.0095 0.0184 0.035
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0063 0.0148
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Plasmodium vivax vivapain-1 0.0663 0.1692 0.548
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0075 0.013 0.013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0063 0.0063
Toxoplasma gondii histone deacetylase HDAC3 0.0085 0.0157 0.0297
Loa Loa (eye worm) histone deacetylase 3 0.0085 0.0157 0.0157
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0043 0.0043
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0307 0.0746 0.2398
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0663 0.1692 0.1692
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0076 0.0076
Echinococcus granulosus biogenic amine 5HT receptor 0.0452 0.1132 0.1132
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Brugia malayi Pre-SET motif family protein 0.069 0.1763 0.1763
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0163 0.0365 0.0692
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Trypanosoma brucei Metacaspase-4 0.0149 0.0326 0.0618
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0063 0.0063
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0196 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0616 0.1568 0.1568
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) histone deacetylase 11 0.0041 0.004 0.004
Schistosoma mansoni cpg binding protein 0.0063 0.0098 0.0098
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0043 0.0043
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0043 0.0043
Echinococcus granulosus endonuclease exonuclease phosphatase 0.02 0.0464 0.0464
Onchocerca volvulus 0.0104 0.0206 0.0373
Brugia malayi Calcium binding EGF domain containing protein 0.0045 0.005 0.005
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0035 0.0024 0.0046
Echinococcus multilocularis calpain 7 (C02 family) 0.1091 0.2829 0.2829
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0296 0.0718 0.0718
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0043
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0043 0.0043
Brugia malayi Cell death protein 3 precursor 0.0364 0.0899 0.0899
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1686 0.4407 0.4407
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0024 0.0048
Loa Loa (eye worm) hypothetical protein 0.2919 0.7684 0.7684
Brugia malayi calpain family protein 1 0.2919 0.7684 0.7684
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0165 0.0369 0.0369
Leishmania major histone deacetylase, putative 0.0095 0.0184 0.035
Leishmania major calmodulin, putative 0.0163 0.0365 0.0692
Echinococcus multilocularis histone deacetylase 7 0.0095 0.0184 0.0184
Onchocerca volvulus 0.0101 0.02 0.0361
Trichomonas vaginalis calmodulin-2, putative 0.0163 0.0365 0.0988
Schistosoma mansoni chromatin regulatory protein sir2 0.0136 0.0293 0.0293
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.2829
Echinococcus granulosus Glycosyl transferase family 35 0.0109 0.022 0.022
Echinococcus multilocularis peroxidasin 0.0507 0.1279 0.1279
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0197 0.0197
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Trichomonas vaginalis esterase, putative 0.011 0.0222 0.0592
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0043 0.0043
Brugia malayi Papain family cysteine protease containing protein 0.0307 0.0746 0.0746
Echinococcus multilocularis GA binding protein alpha chain 0.0147 0.0321 0.0321
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0307 0.0746 0.0746
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Giardia lamblia Cathepsin B precursor 0.0307 0.0746 0.2046
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0075 0.013 0.0391
Brugia malayi Importin beta-1 subunit 0.0058 0.0084 0.0084
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Brugia malayi Trypsin family protein 0.0196 0.0451 0.0451
Echinococcus multilocularis calmodulin 0.0163 0.0365 0.0365
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Onchocerca volvulus 0.0045 0.005 0.0075
Brugia malayi programmed cell death protein 6 0.0163 0.0365 0.0365
Toxoplasma gondii centrin, putative 0.0163 0.0365 0.0692
Mycobacterium tuberculosis Probable hydrolase 0.011 0.0222 0.0479
Trypanosoma brucei mitochondrial calcium uptake 1 0.0163 0.0365 0.0692
Brugia malayi Flap endonuclease-1 0.0029 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0307 0.0746 0.0746
Toxoplasma gondii PAN domain-containing protein 0.003 0.001 0.0019
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0043 0.0043
Onchocerca volvulus 0.0059 0.0089 0.015
Onchocerca volvulus 0.1186 0.308 0.5831
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0154 0.034 0.034
Toxoplasma gondii hypothetical protein 0.0317 0.0773 0.1465
Onchocerca volvulus 0.0046 0.0053 0.0082
Mycobacterium tuberculosis Probable lipase LipE 0.011 0.0222 0.0479
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0035 0.0024 0.0041
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0075 0.013 0.0246
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0307 0.0746 0.2046
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0818 0.2102 0.4526
Echinococcus multilocularis fibropellin Ia 0.0045 0.005 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.058 0.058
Echinococcus granulosus caspase 0.0296 0.0718 0.0718
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0074 0.0074
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0196 0.0451 0.0451
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0055 0.0077 0.0147
Brugia malayi Cathepsin L-like precursor 0.1186 0.308 0.308
Echinococcus granulosus calpain 0.1091 0.2829 0.2829
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.009 0.009
Onchocerca volvulus 0.0307 0.0746 0.1397
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0043 0.0043
Echinococcus granulosus proteasome prosome macropain 0.0165 0.0369 0.0369
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Mycobacterium tuberculosis Hypothetical protein 0.0318 0.0775 0.1668
Loa Loa (eye worm) hypothetical protein 0.0073 0.0125 0.0125
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) prolyl oligopeptidase 0.0237 0.056 0.056
Plasmodium vivax aspartyl proteinase, putative 0.0055 0.0077 0.0221
Echinococcus multilocularis proteasome (prosome, macropain) 0.0165 0.0369 0.0369
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Leishmania major calmodulin-like protein 0.0163 0.0365 0.0692
Loa Loa (eye worm) hypothetical protein 0.0073 0.0125 0.0125
Echinococcus granulosus slit 2 protein 0.0045 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0092
Echinococcus multilocularis apoptotic protease activating factor 1 0.0216 0.0504 0.0504
Trichomonas vaginalis calcineurin B subunit, putative 0.0163 0.0365 0.0988
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0096 0.0187 0.0187
Plasmodium falciparum plasmepsin X 0.0313 0.0763 0.2454
Entamoeba histolytica protein kinase, putative 0.0775 0.1989 0.6447
Onchocerca volvulus 0.0055 0.0077 0.0128
Trypanosoma cruzi caltractin, putative 0.0163 0.0365 0.0365
Brugia malayi prolyl oligopeptidase family protein 0.0237 0.056 0.056
Echinococcus granulosus survival motor neuron protein 1 0.0497 0.1251 0.1251
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0307 0.0746 0.2046
Toxoplasma gondii microneme protein MIC4 0.003 0.001 0.0019
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0165 0.0369 0.1
Trypanosoma cruzi calmodulin, putative 0.0163 0.0365 0.0365
Toxoplasma gondii preprocathepsin c precursor, putative 0.0307 0.0746 0.1414
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.069 0.1763 0.1763
Loa Loa (eye worm) cytochrome P450 family protein 0.0105 0.0211 0.0211
Schistosoma mansoni inhibitor of apoptosis protein 0.0181 0.0413 0.0413
Echinococcus multilocularis protein jagged 1 0.0045 0.005 0.005
Echinococcus multilocularis acylamino acid releasing enzyme 0.0237 0.056 0.056
Echinococcus granulosus neurocalcin 0.0163 0.0365 0.0365
Echinococcus multilocularis chromatin regulatory protein sir2 0.0136 0.0293 0.0293
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0163 0.0365 0.1157
Onchocerca volvulus 0.0507 0.1279 0.241
Loa Loa (eye worm) hypothetical protein 0.0356 0.0877 0.0877
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Schistosoma mansoni rab 0.0163 0.0365 0.0365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0663 0.1692 0.4676
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.0192 0.0192
Onchocerca volvulus Prolyl endopeptidase homolog 0.2012 0.5275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0307 0.0746 0.2046
Onchocerca volvulus Peroxidasin homolog 0.0507 0.1279 0.241
Plasmodium vivax NAD-dependent deacetylase, putative 0.0035 0.0024 0.0048
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0307 0.0746 0.2398
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0252 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0307 0.0746 0.2046
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0326 0.0879
Echinococcus granulosus caspase 2 0.0364 0.0899 0.0899
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0163 0.0365 0.0365
Echinococcus multilocularis serotonin receptor 0.0154 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0123 0.0259 0.0259
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0058 0.0058
Toxoplasma gondii microneme protein MIC17B 0.003 0.001 0.0019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0001 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.2145 0.5628 0.5628
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0044 0.0044
Giardia lamblia Cathepsin L precursor 0.0307 0.0746 0.2046
Schistosoma mansoni survival motor neuron protein 0.0101 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0104 0.0206 0.0206
Onchocerca volvulus 0.0196 0.0451 0.0837
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Leishmania major kinesin, putative 0.0774 0.1988 0.3768
Schistosoma mansoni lamin 0.0054 0.0075 0.0075
Echinococcus granulosus transmembrane protease serine 3 0.0196 0.0451 0.0451
Echinococcus multilocularis slit 2 protein 0.0045 0.005 0.005
Schistosoma mansoni flap endonuclease-1 0.0027 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0196 0.0451 0.0451
Brugia malayi Animal haem peroxidase family protein 0.0507 0.1279 0.1279
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0022 0.0022
Trypanosoma cruzi metacaspase 5, putative 0.0149 0.0326 0.0326
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0063 0.0063
Brugia malayi Peroxidasin 0.0507 0.1279 0.1279
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) cathepsin B 0.1384 0.3608 0.3608
Echinococcus multilocularis neurocalcin 0.0163 0.0365 0.0365
Trichomonas vaginalis ran, putative 0.0042 0.0044 0.0096
Brugia malayi Papain family cysteine protease containing protein 0.0307 0.0746 0.0746
Toxoplasma gondii aspartyl protease ASP3 0.0313 0.0763 0.1446
Echinococcus granulosus cathepsin L cysteine proteinase 0.1186 0.308 0.308
Giardia lamblia Hypothetical protein 0.0307 0.0746 0.2046
Giardia lamblia Hypothetical protein 0.0136 0.0293 0.0789
Trypanosoma cruzi I/6 autoantigen, putative 0.0163 0.0365 0.0365
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.022 0.022
Trypanosoma cruzi histone deacetylase, putative 0.0095 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0452 0.1132 0.1132
Schistosoma mansoni hypothetical protein 0.0101 0.02 0.02
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0331 0.0809 0.0809
Echinococcus multilocularis programmed cell death protein 0.017 0.0383 0.0383
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0075 0.013 0.013
Brugia malayi calcium-binding protein 0.0163 0.0365 0.0365
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.009 0.009
Echinococcus multilocularis calpain A 0.3085 0.8124 0.8124
Plasmodium vivax importin-beta 2, putative 0.0058 0.0084 0.0244
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0048 0.006 0.0114
Brugia malayi Cathepsin L-like cysteine proteinase 0.0829 0.2134 0.2134
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0307 0.0746 0.2398
Schistosoma mansoni centrin-related 0.0163 0.0365 0.0365
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0307 0.0746 0.2046
Loa Loa (eye worm) hypothetical protein 0.011 0.0222 0.0222
Onchocerca volvulus 0.1186 0.308 0.5831
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0317 0.0773 0.2121
Schistosoma mansoni microtubule-associated protein tau 0.151 0.3942 0.3942
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0307 0.0746 0.0746
Entamoeba histolytica hypothetical protein 0.0307 0.0746 0.2398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Trypanosoma cruzi centrin, putative 0.017 0.0383 0.0383
Echinococcus granulosus inhibitor of apoptosis protein 0.0181 0.0413 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0307 0.0746 0.2046
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0063 0.0063
Trypanosoma cruzi kinesin, putative 0.0774 0.1988 0.1988
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0151 0.0332 0.0896
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0075 0.013 0.013
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0035 0.0024 0.0046
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3791 1 1
Toxoplasma gondii exonuclease III APE 0.006 0.009 0.0171
Loa Loa (eye worm) CYP4Cod1 0.0054 0.0074 0.0074
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0043 0.0043
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0009 0.0009
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.02 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0055 0.0077 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0663 0.1692 0.1692
Trypanosoma brucei cysteine peptidase C (CPC) 0.1384 0.3608 0.684
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0326 0.0879
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Trypanosoma brucei Calpain-like protein 2 0.0317 0.0773 0.1465
Trichomonas vaginalis histone deacetylase, putative 0.0085 0.0157 0.0409
Plasmodium vivax unspecified product 0.0663 0.1692 0.548
Echinococcus multilocularis neuronal calcium sensor 0.0163 0.0365 0.0365
Trypanosoma cruzi histone deacetylase, putative 0.0095 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0307 0.0746 0.0746
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0009 0.0009
Echinococcus multilocularis histone deacetylase 1 0.0085 0.0157 0.0157
Plasmodium vivax proteasome subunit beta type-2, putative 0.0048 0.006 0.0164
Echinococcus granulosus neuronal calcium sensor 0.0163 0.0365 0.0365
Brugia malayi aspartic protease BmAsp-2, identical 0.0055 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Echinococcus granulosus calpain 5 0.1091 0.2829 0.2829
Plasmodium falciparum serine repeat antigen 3 0.0307 0.0746 0.2398
Onchocerca volvulus 0.0165 0.037 0.0684
Plasmodium falciparum plasmepsin II 0.0055 0.0077 0.0221
Brugia malayi hypothetical protein 0.0094 0.018 0.018
Loa Loa (eye worm) aspartyl protease 6 0.0055 0.0077 0.0077
Toxoplasma gondii centrin 0.0163 0.0365 0.0692
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0276 0.0276
Echinococcus multilocularis calmodulin 0.0163 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0075 0.0075
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0206 0.0206
Brugia malayi Proteasome A-type and B-type family protein 0.0165 0.0369 0.0369
Onchocerca volvulus Putative cubilin 0.0045 0.005 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0307 0.0746 0.2046
Schistosoma mansoni neuronal calcium sensor 0.0163 0.0365 0.0365
Giardia lamblia Cathepsin B precursor 0.1384 0.3608 1
Schistosoma mansoni neprilysin-2 (M13 family) 0.0049 0.006 0.006
Entamoeba histolytica grainin, putative 0.0165 0.0371 0.1176
Trypanosoma brucei calpain-like protein, putative 0.1091 0.2829 0.5364
Schistosoma mansoni memapsin-2 (A01 family) 0.0498 0.1253 0.1253
Leishmania major histone deacetylase, putative 0.0085 0.0157 0.0297
Mycobacterium tuberculosis Probable peptidase 0.0818 0.2102 0.4526
Echinococcus multilocularis cathepsin L 0.0307 0.0746 0.0746
Schistosoma mansoni hypothetical protein 0.0163 0.0365 0.0365
Plasmodium vivax plasmepsin IV, putative 0.0055 0.0077 0.0221
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0035 0.0024 0.0048
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0055 0.0077 0.0077
Trypanosoma cruzi metacaspase, putative 0.0149 0.0326 0.0326
Trypanosoma cruzi cysteine peptidase, putative 0.1289 0.3353 0.3353
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0317 0.0773 0.2121
Mycobacterium tuberculosis Conserved protein 0.011 0.0222 0.0479
Echinococcus granulosus cysteine protease 0.0663 0.1692 0.1692
Brugia malayi Cadherin domain containing protein 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0005 0.0005
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0044 0.0044
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Entamoeba histolytica cysteine protease, putative 0.0307 0.0746 0.2398
Brugia malayi Papain family cysteine protease containing protein 0.0307 0.0746 0.0746
Giardia lamblia Proteasome subunit beta type 2 0.0048 0.006 0.014
Schistosoma mansoni notch 0.0045 0.005 0.005
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0164 0.0366 0.0366
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0044 0.0044
Plasmodium vivax aspartyl proteinase, putative 0.0055 0.0077 0.0221
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0043 0.0043
Echinococcus granulosus geminin 0.017 0.0382 0.0382
Onchocerca volvulus 0.0165 0.0371 0.0685
Loa Loa (eye worm) hypothetical protein 0.0055 0.0077 0.0077
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Entamoeba histolytica cysteine proteinase, putative 0.0663 0.1692 0.548
Echinococcus multilocularis calpain family protein 1, d 0.2145 0.5628 0.5628
Loa Loa (eye worm) hypothetical protein 0.0181 0.0413 0.0413
Brugia malayi Ets-domain containing protein 0.0147 0.0321 0.0321
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0063 0.0119
Echinococcus granulosus beta LACTamase domain containing family member 0.011 0.0222 0.0222
Echinococcus multilocularis geminin 0.017 0.0382 0.0382
Onchocerca volvulus Glycogen phosphorylase homolog 0.0109 0.022 0.0398
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.022 0.0685
Trypanosoma brucei histone deacetylase 4 0.0095 0.0184 0.035
Brugia malayi prolyl oligopeptidase family protein 0.2012 0.5275 0.5275
Loa Loa (eye worm) proteasome subunit beta type 2 0.0048 0.006 0.006
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0165 0.0369 0.1
Leishmania major hypothetical protein, conserved 0.0046 0.0053 0.0101
Loa Loa (eye worm) hypothetical protein 0.1186 0.308 0.308
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Echinococcus multilocularis neurogenic locus notch protein 0.0045 0.005 0.005
Toxoplasma gondii histone deacetylase SIR2-like 0.0035 0.0024 0.0046
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0452 0.1132 0.1132
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0197 0.0197
Echinococcus multilocularis notch 0.0045 0.005 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.5364
Loa Loa (eye worm) histone deacetylase 0.0095 0.0184 0.0184
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0307 0.0746 0.2398
Trypanosoma brucei oligopeptidase b 0.0818 0.2102 0.3986
Trypanosoma brucei calpain, putative 0.0317 0.0773 0.1465
Plasmodium falciparum serine repeat antigen 4 0.0307 0.0746 0.2398
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0045 0.005 0.005
Plasmodium falciparum cysteine proteinase falcipain 3 0.1186 0.308 1
Brugia malayi Cadherin domain containing protein 0.0045 0.005 0.005
Echinococcus multilocularis Glycosyl transferase, family 35 0.0109 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0043
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0054 0.0074 0.0351
Mycobacterium tuberculosis Conserved protein 0.011 0.0222 0.0479
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0829 0.2134 0.2134
Trichomonas vaginalis calmodulin, putative 0.0165 0.0371 0.1003
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0048 0.006 0.006
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0044 0.0096
Plasmodium falciparum serine repeat antigen 7 0.0307 0.0746 0.2398
Onchocerca volvulus 0.01 0.0197 0.0355
Toxoplasma gondii PAN domain-containing protein 0.003 0.001 0.0019
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Toxoplasma gondii cathepsin CPC1 0.0307 0.0746 0.1414
Loa Loa (eye worm) hypothetical protein 0.0307 0.0746 0.0746
Echinococcus granulosus calpain A 0.3085 0.8124 0.8124
Loa Loa (eye worm) hypothetical protein 0.0094 0.018 0.018
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0048 0.006 0.0164
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0163 0.0365 0.0988
Trypanosoma brucei histone deacetylase, putative 0.0095 0.0184 0.035
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0573 0.1452 0.1452
Plasmodium falciparum plasmepsin VIII, putative 0.0055 0.0077 0.0221
Brugia malayi Cathepsin L-like precursor 0.0356 0.0877 0.0877
Onchocerca volvulus Cathepsin L homolog 0.1186 0.308 0.5831
Toxoplasma gondii hypothetical protein 0.003 0.001 0.0019
Entamoeba histolytica cysteine proteinase, putative 0.0663 0.1692 0.548
Schistosoma mansoni cpg binding protein 0.0063 0.0098 0.0098
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3083 0.8118 0.8118
Plasmodium falciparum serine repeat antigen 9 0.0307 0.0746 0.2398
Leishmania major sir2-family protein-like protein 0.0035 0.0024 0.0046
Schistosoma mansoni ef hand domain family member A2 0.0163 0.0365 0.0365
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.058 0.058
Echinococcus granulosus Dipeptidyl peptidase 9 0.0331 0.0809 0.0809
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0331 0.0809 0.1534
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0222 0.0222
Brugia malayi Histone deacetylase family protein 0.0095 0.0184 0.0184
Echinococcus granulosus peroxidasin 0.0507 0.1279 0.1279
Plasmodium falciparum calpain 0.0317 0.0773 0.2486
Schistosoma mansoni histone deacetylase 1 2 3 0.0041 0.004 0.004
Onchocerca volvulus Huntingtin homolog 0.0123 0.0259 0.0472
Loa Loa (eye worm) hypothetical protein 0.0034 0.0022 0.0022
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0043 0.0043
Brugia malayi hypothetical protein 0.0497 0.1251 0.1251
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0326 0.0879
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0044 0.0044
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0049 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0663 0.1692 0.4676
Entamoeba histolytica cysteine proteinase, putative 0.1186 0.308 1
Brugia malayi Cathepsin L-like precursor 0.1186 0.308 0.308
Trichomonas vaginalis myosin light chain 1, putative 0.0163 0.0365 0.0988
Plasmodium falciparum serine repeat antigen 6 0.0307 0.0746 0.2398
Brugia malayi CXXC zinc finger family protein 0.0059 0.0089 0.0089
Echinococcus multilocularis enteropeptidase 0.0196 0.0451 0.0451
Schistosoma mansoni ran 0.0042 0.0044 0.0044
Schistosoma mansoni calpain-2 (C02 family) 0.0317 0.0773 0.0773
Brugia malayi histone deacetylase 1 (HD1) 0.0085 0.0157 0.0157
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0045 0.005 0.005
Echinococcus granulosus neural cadherin 0.0045 0.005 0.005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.009 0.0225
Echinococcus multilocularis lamin dm0 0.0054 0.0075 0.0075
Echinococcus granulosus chromatin regulatory protein sir2 0.0136 0.0293 0.0293
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0222 0.0592
Trypanosoma cruzi cruzipain precursor, putative 0.1289 0.3353 0.3353
Echinococcus granulosus histone deacetylase 3 0.0085 0.0157 0.0157
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0307 0.0746 0.0746
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0063 0.0148
Trypanosoma cruzi 20S proteasome subunit 0.0048 0.006 0.006
Plasmodium vivax vivapain-2 0.1186 0.308 1
Brugia malayi Cytochrome P450 family protein 0.0105 0.0211 0.0211
Loa Loa (eye worm) animal heme peroxidase 0.0507 0.1279 0.1279
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.009 0.0263
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0307 0.0746 0.2046
Loa Loa (eye worm) hypothetical protein 0.0125 0.0264 0.0264
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0331 0.0809 0.1534
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0307 0.0746 0.0746
Plasmodium vivax aspartyl protease, putative 0.0313 0.0763 0.2454
Brugia malayi calpain 5 0.0774 0.1988 0.1988
Giardia lamblia Hypothetical protein 0.0318 0.0775 0.2127
Toxoplasma gondii calmodulin CAM1 0.0165 0.0371 0.0702
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0056 0.012
Trichomonas vaginalis calpain, putative 0.0317 0.0773 0.2121
Mycobacterium tuberculosis Long conserved protein 0.0318 0.0775 0.1668
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0663 0.1692 0.1692
Echinococcus granulosus cathepsin L cysteine protease 0.0663 0.1692 0.1692
Brugia malayi RNA, U transporter 1 0.0164 0.0367 0.0367
Brugia malayi calpain 7 0.1091 0.2829 0.2829
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0044 0.0044
Schistosoma mansoni notch 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0151 0.0332 0.0332
Trypanosoma brucei histone deacetylase 1 0.0085 0.0157 0.0297
Onchocerca volvulus Neurogenic locus notch homolog 0.0045 0.005 0.0076
Loa Loa (eye worm) animal heme peroxidase 0.0507 0.1279 0.1279
Onchocerca volvulus 0.0163 0.0365 0.0674
Trypanosoma cruzi hypothetical protein, conserved 0.0237 0.056 0.056
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Toxoplasma gondii microneme protein MIC17A 0.003 0.001 0.0019
Echinococcus granulosus histone deacetylase 6 0.0101 0.02 0.02
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Brugia malayi cathepsin F-like cysteine proteinase 0.0307 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0237 0.056 0.056
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0163 0.0365 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Schistosoma mansoni chromatin regulatory protein sir2 0.0035 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0055 0.0128
Mycobacterium tuberculosis Conserved protein 0.011 0.0222 0.0479
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0085 0.0157 0.0409
Leishmania major cathepsin L-like protease 0.1289 0.3353 0.6357
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Onchocerca volvulus 0.0785 0.2016 0.3811
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0043 0.0092
Plasmodium falciparum plasmepsin I 0.0055 0.0077 0.0221
Trypanosoma cruzi cruzipain precursor, putative 0.0356 0.0877 0.0877
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0085 0.0157 0.0409
Loa Loa (eye worm) histone deacetylase 1 0.0085 0.0157 0.0157
Brugia malayi MAP kinase sur-1 0.005 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0307 0.0746 0.2046
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0149 0.0326 0.0618
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0222 0.0222
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0282 0.1342
Onchocerca volvulus 0.0196 0.0451 0.0837
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0395 0.0981 0.0981
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0663 0.1692 0.1692
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1186 0.308 0.8533
Brugia malayi Histone deacetylase family protein 0.0095 0.0184 0.0184
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Brugia malayi calpain 5 0.0317 0.0773 0.0773
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0237 0.056 0.1794
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Trypanosoma brucei calpain-like protein, putative 0.1091 0.2829 0.5364
Brugia malayi Pepsin A precursor 0.0055 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Brugia malayi mbt repeat family protein 0.0048 0.0058 0.0058
Schistosoma mansoni caspase-3 (C14 family) 0.0296 0.0718 0.0718
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0317 0.0773 0.0773
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0035 0.0024 0.0048
Echinococcus multilocularis histone deacetylase 6 0.0101 0.02 0.02
Trypanosoma brucei calpain-like protein, putative 0.1091 0.2829 0.5364
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.001 0.001
Trypanosoma brucei centrin, putative 0.0163 0.0365 0.0692
Onchocerca volvulus 0.011 0.0222 0.0403
Echinococcus multilocularis protein jagged 1 0.0045 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Brugia malayi Animal haem peroxidase family protein 0.0507 0.1279 0.1279
Leishmania major hypothetical protein, conserved 0.0165 0.0371 0.0702
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0058 0.0058
Brugia malayi EF hand family protein 0.0165 0.0371 0.0371
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0044 0.0113
Loa Loa (eye worm) MBCTL1 0.0054 0.0076 0.0076
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.001 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Entamoeba histolytica calmodulin, putative 0.0163 0.0365 0.1157
Brugia malayi Cytochrome P450 family protein 0.0054 0.0074 0.0074
Echinococcus multilocularis microtubule associated protein 2 0.151 0.3942 0.3942
Schistosoma mansoni chromatin regulatory protein sir2 0.0035 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Brugia malayi Calmodulin-like protein 0.0163 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0307 0.0746 0.0746
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0063 0.0119
Leishmania major calcineurin B subunit, putative 0.0163 0.0365 0.0692
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Loa Loa (eye worm) hypothetical protein 0.0054 0.0075 0.0075
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3791 1 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.01 0.0197 0.0197
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0165 0.0371 0.0371
Entamoeba histolytica cysteine protease, putative 0.0307 0.0746 0.2398
Leishmania major cathepsin L-like protease 0.1186 0.308 0.5839
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0009 0.0018
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0317 0.0773 0.0773
Brugia malayi proteasome subunit beta type 1 0.0075 0.013 0.013
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Brugia malayi Papain family cysteine protease containing protein 0.0663 0.1692 0.1692
Onchocerca volvulus 0.0163 0.0365 0.0674
Onchocerca volvulus 0.0196 0.0451 0.0837
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0317 0.0773 0.2121
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.011 0.0222 0.0222
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0055 0.0128
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0237 0.056 0.056
Brugia malayi PXA domain containing protein 0.0042 0.0043 0.0043
Echinococcus granulosus dnaJ subfamily B 0.0437 0.1093 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0092
Loa Loa (eye worm) EF hand family protein 0.0163 0.0365 0.0365
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.022 0.0584
Toxoplasma gondii EGF family domain-containing protein 0.0045 0.005 0.0094
Brugia malayi transcriptional regulator, Sir2 family protein 0.0136 0.0293 0.0293
Trichomonas vaginalis calcineurin B subunit, putative 0.0165 0.0371 0.1003
Trichomonas vaginalis set domain proteins, putative 0.0785 0.2016 0.5576
Mycobacterium tuberculosis Probable esterase LipL 0.011 0.0222 0.0479
Giardia lamblia Transglutaminase/protease, putative 0.0318 0.0775 0.2127
Entamoeba histolytica cysteine proteinase, putative 0.0663 0.1692 0.548
Giardia lamblia Cathepsin B precursor 0.0307 0.0746 0.2046
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0573 0.1452 0.1452
Trypanosoma brucei I/6 autoantigen 0.0163 0.0365 0.0692
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0317 0.0773 0.0773
Schistosoma mansoni hypothetical protein 0.0303 0.0735 0.0735
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.011 0.0222 0.0479
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0154 0.034 0.034
Schistosoma mansoni cathepsin D (A01 family) 0.0356 0.0877 0.0877
Toxoplasma gondii subtilisin SUB12 0.003 0.001 0.0019
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0331 0.0809 0.1534
Toxoplasma gondii EF hand domain-containing protein 0.0163 0.0365 0.0692
Echinococcus granulosus histone deacetylase 0.0095 0.0184 0.0184
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1186 0.308 1
Giardia lamblia Cathepsin L-like protease 0.0307 0.0746 0.2046
Echinococcus granulosus histone deacetylase 8 0.0041 0.004 0.004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0035 0.0024 0.0041
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0075 0.013 0.0246
Plasmodium falciparum metacaspase-like protein 0.0149 0.0326 0.103
Onchocerca volvulus 0.1186 0.308 0.5831
Trypanosoma brucei antigen, putative 0.1091 0.2829 0.5364
Mycobacterium ulcerans hypothetical protein 0.0196 0.0451 0.2143
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0009 0.0018
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.009 0.5
Brugia malayi calpain D 0.0317 0.0773 0.0773
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0058 0.0058
Plasmodium vivax vivapain-3 0.0663 0.1692 0.548
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0237 0.056 0.1531
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2919 0.7684 0.7684
Entamoeba histolytica cysteine protease, putative 0.1186 0.308 1
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0043 0.0043
Plasmodium falciparum histone deacetylase, putative 0.0095 0.0184 0.057
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0181 0.0413 0.0413
Onchocerca volvulus 0.0054 0.0075 0.0123
Echinococcus multilocularis inhibitor of apoptosis protein 0.0181 0.0413 0.0413
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Schistosoma mansoni histone deacetylase 4 5 0.0095 0.0184 0.0184
Schistosoma mansoni chromatin regulatory protein sir2 0.0035 0.0024 0.0024
Schistosoma mansoni slit 0.0045 0.005 0.005
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0063 0.0119
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.009 0.009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Brugia malayi Peptidase family M13 containing protein 0.0096 0.0187 0.0187
Plasmodium falciparum plasmepsin IX 0.0313 0.0763 0.2454
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0818 0.2102 0.2102
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0395 0.0981 0.0981
Entamoeba histolytica cysteine proteinase 1, putative 0.0663 0.1692 0.548
Plasmodium vivax unspecified product 0.0356 0.0877 0.2827
Echinococcus multilocularis endothelin converting enzyme 1 0.0096 0.0187 0.0187
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0149 0.0326 0.0618
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0616 0.1568 0.1568
Loa Loa (eye worm) hypothetical protein 0.0085 0.0157 0.0157
Giardia lamblia High cysteine protein 0.0045 0.005 0.0112
Toxoplasma gondii PAN domain-containing protein 0.003 0.001 0.0019
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0043 0.0043
Echinococcus granulosus cathepsin b 0.3791 1 1
Plasmodium vivax unspecified product 0.0307 0.0746 0.2398
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0307 0.0746 0.2046
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Leishmania major hypothetical protein, conserved 0.0317 0.0773 0.1465
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Echinococcus multilocularis snurportin 1 0.0616 0.1568 0.1568
Schistosoma mansoni cathepsin B (C01 family) 0.0307 0.0746 0.0746
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.011 0.0222 0.0222
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0151 0.0332 0.0896
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Trypanosoma cruzi metacaspase 5, putative 0.0149 0.0326 0.0326
Schistosoma mansoni cathepsin C 0.0307 0.0746 0.0746
Leishmania major proteasome beta 2 subunit, putative 0.0048 0.006 0.0114
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0053 0.0053
Brugia malayi Trypsin-like protease protein 5 0.0196 0.0451 0.0451
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2012 0.5275 0.5275
Echinococcus granulosus tumor protein p63 0.0708 0.1811 0.1811
Echinococcus granulosus histone deacetylase 6 0.0095 0.0184 0.0184
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0056 0.0266
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Schistosoma mansoni ap endonuclease 0.006 0.009 0.009
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0222 0.0592
Toxoplasma gondii EFHC1, putative 0.0163 0.0365 0.0692
Loa Loa (eye worm) hypothetical protein 0.3791 1 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0085 0.0157 0.0409
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0049 0.006 0.006
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0181 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0058 0.0084 0.0084
Echinococcus granulosus histone deacetylase 7 0.0095 0.0184 0.0184
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.009 0.0194
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0043 0.0043
Schistosoma mansoni histone deacetylase 0.0085 0.0157 0.0157
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0035 0.0024 0.0048
Onchocerca volvulus 0.0829 0.2134 0.4033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.011 0.0222 0.0222
Trypanosoma cruzi cysteine peptidase, putative 0.1289 0.3353 0.3353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0663 0.1692 0.3208
Echinococcus multilocularis tumor protein p63 0.0708 0.1811 0.1811
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0063 0.0063
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0043 0.0043
Plasmodium falciparum plasmepsin III 0.0055 0.0077 0.0221
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.022 0.0584
Onchocerca volvulus Histone deacetylase 10 homolog 0.0041 0.004 0.0056
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Brugia malayi Ets-domain containing protein 0.0147 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0216 0.0504 0.0504
Giardia lamblia Cathepsin L precursor 0.0307 0.0746 0.2046
Brugia malayi GCC2 and GCC3 family protein 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Trichomonas vaginalis centrin, putative 0.0163 0.0365 0.0988
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0326 0.0879
Loa Loa (eye worm) calpain D 0.0317 0.0773 0.0773
Schistosoma mansoni notch 0.0045 0.005 0.005
Trichomonas vaginalis histone deacetylase, putative 0.0085 0.0157 0.0409
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0035 0.0024 0.0041
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0044 0.0044
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0058 0.0058
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.0282 0.0535
Echinococcus granulosus glycogen phosphorylase 0.0109 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0123 0.0259 0.0259
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1091 0.2829 0.2829
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0048 0.006 0.006
Onchocerca volvulus 0.0318 0.0775 0.1452
Loa Loa (eye worm) animal heme peroxidase 0.0507 0.1279 0.1279
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Entamoeba histolytica hypothetical protein, conserved 0.0165 0.0371 0.1176
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1186 0.308 0.308
Toxoplasma gondii ABC1 family protein 0.011 0.0222 0.0422
Trypanosoma brucei Calpain-like protein 1.1 0.0317 0.0773 0.1465
Trichomonas vaginalis histone deacetylase, putative 0.0085 0.0157 0.0409
Echinococcus multilocularis histone deacetylase 6 0.0095 0.0184 0.0184
Echinococcus multilocularis cathepsin L 0.0663 0.1692 0.1692
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Echinococcus granulosus programmed cell death protein 0.017 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Brugia malayi hypothetical protein 0.0507 0.1279 0.1279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Leishmania major importin beta-1 subunit, putative 0.0047 0.0055 0.0105
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0089 0.0089
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.0282 0.0535
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.0773 0.0773
Echinococcus granulosus cathepsin l cysteine peptidase 0.1186 0.308 0.308
Trichomonas vaginalis peptide N-glycanase, putative 0.0318 0.0775 0.2127
Schistosoma mansoni biogenic amine (5HT) receptor 0.0154 0.034 0.034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Echinococcus multilocularis caspase 3 0.0148 0.0323 0.0323
Echinococcus granulosus biogenic amine 5HT receptor 0.0154 0.034 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.0746 0.2046
Mycobacterium leprae Conserved hypothetical protein 0.0318 0.0775 0.3685
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0147 0.0321 0.0321
Toxoplasma gondii aspartyl protease ASP1 0.0055 0.0077 0.0147
Echinococcus multilocularis expressed protein 0.0817 0.2101 0.2101
Loa Loa (eye worm) hypothetical protein 0.0307 0.0746 0.0746
Plasmodium vivax histone deacetylase, putative 0.0041 0.004 0.0099
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0075 0.0075
Plasmodium vivax aspartyl protease, putative 0.0313 0.0763 0.2454
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0307 0.0746 0.2398
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0048 0.006 0.006
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0043 0.0043
Plasmodium vivax proteasome subunit beta type-1, putative 0.0075 0.013 0.0391
Echinococcus granulosus neurogenic locus notch protein 0.0045 0.005 0.005
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0163 0.0365 0.0365
Leishmania major centrin, putative,caltractin, putative 0.0163 0.0365 0.0692
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0035 0.0024 0.0024
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0076 0.0076
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.022 0.0685
Echinococcus granulosus calumenin 0.0165 0.0371 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0317 0.0773 0.2121
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0035 0.0024 0.0052
Brugia malayi cathepsin L precursor 0.0307 0.0746 0.0746
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0076 0.0076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3791 1 1
Loa Loa (eye worm) hypothetical protein 0.0237 0.056 0.056
Trypanosoma cruzi metacaspase, putative 0.0149 0.0326 0.0326
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Giardia lamblia Alanyl dipeptidyl peptidase 0.0237 0.056 0.1531
Trypanosoma brucei histone deacetylase 3 0.0095 0.0184 0.035
Echinococcus granulosus delta-like protein 1 0.0045 0.005 0.005
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Trypanosoma cruzi I/6 autoantigen, putative 0.0163 0.0365 0.0365
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Loa Loa (eye worm) beta-lactamase 0.011 0.0222 0.0222
Entamoeba histolytica cysteine proteinase, putative 0.0829 0.2134 0.6918
Echinococcus multilocularis neurogenic locus protein delta 0.0045 0.005 0.005
Echinococcus granulosus GA binding protein alpha chain 0.0147 0.0321 0.0321
Plasmodium falciparum peptidase, putative 0.0237 0.056 0.1794
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0282 0.1342
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0701 0.1792 0.3856
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0307 0.0746 0.0746
Brugia malayi PXA domain containing protein 0.0042 0.0043 0.0043
Loa Loa (eye worm) fli-1 protein 0.0446 0.1115 0.1115
Onchocerca volvulus Peroxidase homolog 0.0507 0.1279 0.241
Onchocerca volvulus 0.011 0.0222 0.0403
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0331 0.0809 0.0809
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0818 0.2102 0.3986
Loa Loa (eye worm) hypothetical protein 0.0054 0.0076 0.0076
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0063 0.0063
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1186 0.308 0.308
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0307 0.0746 0.0746
Leishmania major calmodulin-like protein 0.0163 0.0365 0.0692
Schistosoma mansoni chromatin regulatory protein sir2 0.0136 0.0293 0.0293
Plasmodium falciparum plasmepsin VII 0.0055 0.0077 0.0221
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0136 0.0293 0.0293
Echinococcus granulosus caspase 8 0.0149 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0497 0.1251 0.1251
Trypanosoma brucei prolyl oligopeptidase, putative 0.0818 0.2102 0.3986
Entamoeba histolytica calmodulin, putative 0.0163 0.0365 0.1157
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Entamoeba histolytica histone deacetylase, putative 0.0085 0.0157 0.0479
Onchocerca volvulus 0.0196 0.0451 0.0837
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0237 0.056 0.1531
Loa Loa (eye worm) histone deacetylase 7A 0.0095 0.0184 0.0184
Echinococcus granulosus EF hand domain containing family member A2 0.0165 0.0371 0.0371
Brugia malayi proteasome subunit beta type 2 0.0048 0.006 0.006
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0395 0.0981 0.0981
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Giardia lamblia Proteasome subunit beta type 1 0.0075 0.013 0.0334
Trypanosoma cruzi histone deacetylase, putative 0.0041 0.004 0.004
Entamoeba histolytica cysteine proteinase, putative 0.1186 0.308 1
Schistosoma mansoni mitochondrial solute carrier 0.0163 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0096 0.0187 0.0187
Onchocerca volvulus Chorion peroxidase homolog 0.0507 0.1279 0.241
Echinococcus multilocularis neurogenic locus notch protein 4 0.0045 0.005 0.005
Brugia malayi Histone deacetylase 1 0.0085 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0071 0.0121 0.0121
Echinococcus multilocularis Transglutaminase 0.0318 0.0775 0.0775
Echinococcus granulosus calmodulin 0.0163 0.0365 0.0365
Onchocerca volvulus 0.1186 0.308 0.5831
Trypanosoma brucei histone deacetylase 2 0.0041 0.004 0.0076
Loa Loa (eye worm) hypothetical protein 0.011 0.0222 0.0222
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.0773 0.0773
Echinococcus granulosus EF HAND 1 calcium binding site 0.0163 0.0365 0.0365
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0053 0.0053
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0136 0.0293 0.0293
Toxoplasma gondii hypothetical protein 0.0237 0.056 0.1062
Loa Loa (eye worm) hypothetical protein 0.0149 0.0326 0.0326
Echinococcus multilocularis histone deacetylase 6 0.0095 0.0184 0.0184
Trichomonas vaginalis histone deacetylase, putative 0.0085 0.0157 0.0409
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0063 0.0119
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Mycobacterium ulcerans hypothetical protein 0.0318 0.0775 0.3685
Schistosoma mansoni neuronal calcium sensor 0.0163 0.0365 0.0365
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Trichomonas vaginalis ap endonuclease, putative 0.006 0.009 0.0225
Echinococcus multilocularis protein jagged 2 0.0045 0.005 0.005
Echinococcus granulosus calcium uptake protein 1 0.0165 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0058
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0165 0.0369 0.0369
Onchocerca volvulus Peroxidase homolog 0.0507 0.1279 0.241
Toxoplasma gondii PAN domain-containing protein 0.003 0.001 0.0019
Plasmodium falciparum proteasome subunit beta type-5 0.0165 0.0369 0.1172
Giardia lamblia Cathepsin L-like protease 0.0307 0.0746 0.2046
Leishmania major cathepsin L-like protease 0.1186 0.308 0.5839
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0043 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.5364
Echinococcus granulosus calbindin 32 0.0165 0.0371 0.0371
Brugia malayi Calcium binding EGF domain containing protein 0.0045 0.005 0.005
Echinococcus multilocularis EF hand domain containing family member A2 0.0163 0.0365 0.0365
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0311 0.0311
Giardia lamblia Cathepsin B precursor 0.1384 0.3608 1
Echinococcus granulosus lamin dm0 0.0054 0.0075 0.0075
Loa Loa (eye worm) calmodulin-like protein 0.0163 0.0365 0.0365
Giardia lamblia Encystation-specific protease 0.0307 0.0746 0.2046
Mycobacterium ulcerans lipase LipD 0.011 0.0222 0.1058
Echinococcus multilocularis neurogenic locus protein delta 0.0045 0.005 0.005
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1186 0.308 0.308
Echinococcus multilocularis fat cadherin tumor suppressor 0.0045 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0307 0.0746 0.2046
Loa Loa (eye worm) hypothetical protein 0.0073 0.0125 0.0125
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0035 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0163 0.0365 0.0365
Plasmodium falciparum plasmepsin IV 0.0055 0.0077 0.0221
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.2829
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0197 0.0197
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.5364
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0307 0.0746 0.0746
Schistosoma mansoni cell polarity protein 0.0045 0.005 0.005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Echinococcus multilocularis centrin 2 0.0163 0.0365 0.0365
Trypanosoma cruzi metacaspase, putative 0.0149 0.0326 0.0326
Brugia malayi Trypsin family protein 0.0196 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0356 0.0877 0.0877
Onchocerca volvulus Cell death protein 3 homolog 0.0364 0.0899 0.1688
Toxoplasma gondii histone deacetylase HDAC2 0.0085 0.0157 0.0297
Loa Loa (eye worm) prolyl oligopeptidase 0.0573 0.1452 0.1452
Brugia malayi Animal haem peroxidase family protein 0.0507 0.1279 0.1279
Trypanosoma cruzi cysteine proteinase, putative 0.0663 0.1692 0.1692
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0043
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0058 0.0091
Trypanosoma cruzi cysteine peptidase, putative 0.1186 0.308 0.308
Giardia lamblia Cysteine protease 0.0307 0.0746 0.2046
Leishmania major hypothetical protein, unknown function 0.0317 0.0773 0.1465
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0063 0.0063
Schistosoma mansoni notch 0.0045 0.005 0.005
Toxoplasma gondii histone deacetylase SIR2 0.0035 0.0024 0.0046
Schistosoma mansoni neuronal calcium sensor 0.0163 0.0365 0.0365
Brugia malayi Thioredoxin family protein 0.0318 0.0775 0.0775
Onchocerca volvulus 0.0181 0.0413 0.0764
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0164 0.0366 0.1161
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1384 0.3608 0.684
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0084 0.0084
Mycobacterium ulcerans proteasome PrcB 0.0165 0.0369 0.1756
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Brugia malayi Cytochrome P450 family protein 0.0054 0.0074 0.0074
Brugia malayi aspartic protease BmAsp-1, identical 0.0055 0.0077 0.0077
Trypanosoma cruzi kinesin, putative 0.0774 0.1988 0.1988
Schistosoma mansoni neuronal calcium sensor 0.0163 0.0365 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3791 1 1
Trypanosoma cruzi conserved protein 0.0317 0.0773 0.0773
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0163 0.0365 0.0365
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Entamoeba histolytica prolyl oligopeptidase family protein 0.0237 0.056 0.1794
Trypanosoma brucei Component of motile flagella 41 0.0163 0.0365 0.0692
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0163 0.0365 0.0365
Loa Loa (eye worm) calpain family protein 1 0.2145 0.5628 0.5628
Loa Loa (eye worm) hypothetical protein 0.011 0.0222 0.0222
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Loa Loa (eye worm) hypothetical protein 0.0165 0.037 0.037
Entamoeba histolytica hypothetical protein 0.0042 0.0043 0.0108
Onchocerca volvulus 0.0045 0.005 0.0075
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0829 0.2134 0.5903
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0165 0.0369 0.1172
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0163 0.0365 0.0365
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0048 0.006 0.0114
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1186 0.308 1
Entamoeba histolytica calpain family cysteine protease, putative 0.0317 0.0773 0.2486
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0076 0.0076
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0663 0.1692 0.1692
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0058 0.0058
Loa Loa (eye worm) fibroinase 0.1186 0.308 0.308
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0307 0.0746 0.2398
Entamoeba histolytica calcium-binding protein, putative 0.0163 0.0365 0.1157
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0084 0.016
Mycobacterium ulcerans NAD-dependent deacetylase 0.0035 0.0024 0.0115
Toxoplasma gondii cathepsin B 0.1384 0.3608 0.684
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0063 0.0148
Echinococcus granulosus snurportin 1 0.0616 0.1568 0.1568
Brugia malayi prolyl oligopeptidase family protein 0.0237 0.056 0.056
Echinococcus multilocularis programmed cell death protein 0.017 0.0383 0.0383
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0096 0.0187 0.0403
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0055 0.0128
Schistosoma mansoni importin beta-1 0.0058 0.0084 0.0084
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0165 0.0369 0.0369
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0044 0.0113
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.2829
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0058 0.0058
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0307 0.0746 0.0746
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0326 0.0879
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0055 0.0077 0.0189
Mycobacterium ulcerans hypothetical protein 0.0318 0.0775 0.3685
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0044 0.0083
Leishmania major silent information regulator 2, putative 0.0136 0.0293 0.0556
Echinococcus granulosus calpain 7 C02 family 0.1091 0.2829 0.2829
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0197 0.0373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Echinococcus granulosus fibropellin Ia 0.0045 0.005 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0237 0.056 0.056
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Brugia malayi hypothetical protein 0.0055 0.0077 0.0077
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0063 0.0148
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0044 0.0044
Leishmania major cathepsin L-like protease 0.1289 0.3353 0.6357
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0317 0.0773 0.2121
Schistosoma mansoni cathepsin F (C01 family) 0.1186 0.308 0.308
Plasmodium falciparum histone deacetylase 1 0.0085 0.0157 0.0479
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1186 0.308 0.8533
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Echinococcus granulosus flap endonuclease 1 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0073 0.0125 0.0125
Brugia malayi carbohydrate phosphorylase 0.0109 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0282 0.0282
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Loa Loa (eye worm) programmed cell death protein 6 0.0165 0.0371 0.0371
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0356 0.0877 0.0877
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0311 0.0311
Entamoeba histolytica cysteine protease, putative 0.0307 0.0746 0.2398
Entamoeba histolytica grainin 2 0.017 0.0383 0.1218
Leishmania major protein kinase, putative 0.0164 0.0366 0.0694
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Leishmania major programmed cell death 6 protein-like protein 0.0163 0.0365 0.0692
Entamoeba histolytica hypothetical protein 0.0042 0.0043 0.0108
Entamoeba histolytica calcium binding family protein 0.0163 0.0365 0.1157
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Echinococcus multilocularis calpain 5 0.1091 0.2829 0.2829
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Loa Loa (eye worm) hypothetical protein 0.0096 0.0187 0.0187
Trypanosoma brucei metacaspase 5, putative 0.0149 0.0326 0.0618
Schistosoma mansoni cathepsin S (C01 family) 0.0307 0.0746 0.0746
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0163 0.0365 0.1157
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0317 0.0773 0.1465
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0043 0.0043
Giardia lamblia Transcriptional regulator, Sir2 family 0.0035 0.0024 0.0041
Trypanosoma brucei kinesin, putative 0.0774 0.1988 0.3768
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0035 0.0024 0.0041
Toxoplasma gondii prolyl endopeptidase 0.2012 0.5275 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0055 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.011 0.0222 0.0592
Echinococcus granulosus centrin 2 0.0163 0.0365 0.0365
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.011 0.0222 0.1058
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0136 0.0293 0.0293
Brugia malayi gamma-secretase subunit aph-1 0.0252 0.06 0.06
Schistosoma mansoni reticulocalbin 0.0165 0.0371 0.0371
Trypanosoma cruzi cytochrome P450, putative 0.0054 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0307 0.0746 0.2046
Mycobacterium ulcerans hypothetical protein 0.011 0.0222 0.1058
Trypanosoma brucei caltractin, putative 0.017 0.0383 0.0727
Leishmania major cysteine peptidase A (CPA) 0.1186 0.308 0.5839
Brugia malayi NAD-dependent deacetylase SIRT1 0.0151 0.0332 0.0332
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0063 0.0063
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0136 0.0293 0.0789
Brugia malayi transcriptional regulator, Sir2 family protein 0.0035 0.0024 0.0024
Echinococcus multilocularis survival motor neuron protein 1 0.0497 0.1251 0.1251
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.0773 0.0773
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3083 0.8118 0.8118
Schistosoma mansoni histone deacetylase hda2 0.0101 0.02 0.02
Onchocerca volvulus Cathepsin F homolog 0.1186 0.308 0.5831
Giardia lamblia Cathepsin L precursor 0.0307 0.0746 0.2046
Giardia lamblia Cysteine protease 0.0307 0.0746 0.2046
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Mycobacterium tuberculosis Conserved hypothetical protein 0.0318 0.0775 0.1668
Trypanosoma cruzi calmodulin, putative 0.0163 0.0365 0.0365
Brugia malayi fibroinase precursor 0.0307 0.0746 0.0746
Echinococcus granulosus cathepsin l1 0.1186 0.308 0.308
Entamoeba histolytica hypothetical protein 0.0047 0.0055 0.015
Chlamydia trachomatis glycogen phosphorylase 0.0109 0.022 0.5
Trypanosoma cruzi centrin-3 0.017 0.0383 0.0383
Loa Loa (eye worm) glycogen phosphorylase 0.0109 0.022 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Loa Loa (eye worm) hypothetical protein 0.0071 0.0121 0.0121
Toxoplasma gondii PAN domain-containing protein 0.003 0.001 0.0019
Echinococcus granulosus cathepsin b 0.3791 1 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0307 0.0746 0.2398
Echinococcus granulosus microtubule associated protein 2 0.151 0.3942 0.3942
Toxoplasma gondii microneme protein, putative 0.003 0.001 0.0019
Onchocerca volvulus Cathepsin L homolog 0.1186 0.308 0.5831
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0075 0.013 0.0391
Echinococcus multilocularis lamin 0.0054 0.0075 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0151 0.0332 0.0896
Echinococcus multilocularis calumenin 0.0165 0.0371 0.0371
Plasmodium falciparum histone deacetylase 2 0.0095 0.0184 0.057
Onchocerca volvulus 0.011 0.0222 0.0403
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0307 0.0746 0.0746
Trypanosoma cruzi cysteine protease, putative 0.0663 0.1692 0.1692
Loa Loa (eye worm) calpain family protein 1 0.2919 0.7684 0.7684
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0237 0.056 0.1062
Entamoeba histolytica hypothetical protein 0.0042 0.0043 0.0108
Loa Loa (eye worm) blistered cuticle protein 3 0.0507 0.1279 0.1279
Giardia lamblia Sirtuin type 2 0.0035 0.0024 0.0041
Giardia lamblia Cysteine protease 0.0307 0.0746 0.2046
Trypanosoma cruzi metacaspase, putative 0.0149 0.0326 0.0326
Schistosoma mansoni caspase-7 (C14 family) 0.0296 0.0718 0.0718
Entamoeba histolytica cysteine proteinase, putative 0.0663 0.1692 0.548
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0165 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.0216 0.0504 0.0504
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0045 0.005 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0307 0.0746 0.2046
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0307 0.0746 0.2046
Trypanosoma brucei hypothetical protein, conserved 0.0163 0.0365 0.0692
Brugia malayi Papain family cysteine protease containing protein 0.0663 0.1692 0.1692
Brugia malayi EF hand family protein 0.0163 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Trypanosoma brucei cytochrome P450, putative 0.0054 0.0074 0.014
Plasmodium vivax histone deacetylase, putative 0.0095 0.0184 0.057
Brugia malayi hypothetical protein 0.0196 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Schistosoma mansoni peroxidasin 0.0507 0.1279 0.1279
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0043 0.0043
Echinococcus multilocularis EF hand domain containing family member A2 0.0165 0.0371 0.0371
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0095 0.0184 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0307 0.0746 0.2046
Schistosoma mansoni hypothetical protein 0.017 0.0382 0.0382
Trypanosoma brucei SIR2-like protein 4, putative 0.0035 0.0024 0.0046
Brugia malayi calpain family protein 1 0.2919 0.7684 0.7684
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0165 0.0369 0.0369
Trichomonas vaginalis histone deacetylase, putative 0.0085 0.0157 0.0409
Leishmania major cathepsin L-like protease 0.1186 0.308 0.5839
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1091 0.2829 0.2829
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0149 0.0326 0.0326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Toxoplasma gondii proteasome subunit beta type, putative 0.0165 0.0369 0.07
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0237 0.056 0.056
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0331 0.0809 0.1534
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0307 0.0746 0.2046
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0307 0.0746 0.2398
Mycobacterium ulcerans beta-lactamase 0.011 0.0222 0.1058
Schistosoma mansoni notch 0.0045 0.005 0.005
Onchocerca volvulus 0.0048 0.0058 0.0091
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Echinococcus multilocularis caspase 8 0.0149 0.0326 0.0326
Schistosoma mansoni ran 0.0042 0.0044 0.0044
Brugia malayi Trypsin family protein 0.0196 0.0451 0.0451
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0818 0.2102 0.2102
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.011 0.0222 0.0479
Echinococcus granulosus neurogenic locus notch protein 0.0045 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Schistosoma mansoni calpain-7 (C02 family) 0.1095 0.2838 0.2838
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0663 0.1692 0.3208
Onchocerca volvulus 0.0196 0.0451 0.0837
Trypanosoma brucei protein I/6 0.0163 0.0365 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0365 0.0988
Trypanosoma brucei protein kinase, putative 0.005 0.0063 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0044 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0307 0.0746 0.2046
Brugia malayi prolyl oligopeptidase family protein 0.0573 0.1452 0.1452
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0237 0.056 0.1062
Trypanosoma cruzi calmodulin, putative 0.0163 0.0365 0.0365
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.009 0.0171
Trichomonas vaginalis histone deacetylase, putative 0.0085 0.0157 0.0409
Brugia malayi Cathepsin L-like precursor 0.1186 0.308 0.308
Echinococcus multilocularis transmembrane protease serine 3 0.0196 0.0451 0.0451
Echinococcus multilocularis calbindin 32 0.0165 0.0371 0.0371
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.0773 0.0773
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0048 0.006 0.014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.009 0.009
Trypanosoma cruzi cytochrome P450, putative 0.0054 0.0074 0.0074
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Schistosoma mansoni intermediate filament proteins 0.0054 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0071 0.0121 0.0121
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0181 0.0413 0.0413
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0317 0.0773 0.1465
Brugia malayi Animal haem peroxidase family protein 0.0507 0.1279 0.1279
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0063 0.0063
Brugia malayi intermediate filament protein 0.0054 0.0075 0.0075
Onchocerca volvulus 0.0507 0.1279 0.241
Entamoeba histolytica cysteine protease, putative 0.0307 0.0746 0.2398
Brugia malayi beta-lactamase 0.011 0.0222 0.0222
Plasmodium falciparum serine repeat antigen 1 0.0307 0.0746 0.2398
Schistosoma mansoni histone deacetylase hda2 0.0041 0.004 0.004
Schistosoma mansoni calmodulin 0.0163 0.0365 0.0365
Onchocerca volvulus 0.0054 0.0075 0.0123
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0307 0.0746 0.0746
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Echinococcus granulosus notch 0.0045 0.005 0.005
Trichomonas vaginalis calcium binding protein, putative 0.0163 0.0365 0.0988
Loa Loa (eye worm) hypothetical protein 0.0317 0.0773 0.0773
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0064 0.0064
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Plasmodium vivax plasmepsin V, putative 0.0055 0.0077 0.0221
Loa Loa (eye worm) hypothetical protein 0.0046 0.0053 0.0053
Echinococcus multilocularis cathepsin L cysteine protease 0.1186 0.308 0.308
Entamoeba histolytica cysteine protease, putative 0.0307 0.0746 0.2398
Leishmania major hypothetical protein, conserved 0.0163 0.0365 0.0692
Echinococcus multilocularis caspase 0.0296 0.0718 0.0718
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.2829
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.02 0.02
Loa Loa (eye worm) animal heme peroxidase 0.0507 0.1279 0.1279
Mycobacterium ulcerans putative transglutaminase-like protein 0.0318 0.0775 0.3685
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0043 0.0043
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0165 0.0369 0.0795
Plasmodium falciparum cysteine proteinase falcipain 1 0.0663 0.1692 0.548
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0043 0.0043
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0307 0.0746 0.2046
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0084 0.016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0311 0.0311
Trypanosoma brucei metacaspase 0.0149 0.0326 0.0618
Schistosoma mansoni cathepsin s 0.0356 0.0877 0.0877
Schistosoma mansoni hypothetical protein 0.0318 0.0775 0.0775
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0573 0.1452 0.1452
Schistosoma mansoni glycogen phosphorylase 0.0109 0.022 0.022
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.017 0.0382 0.0382
Trypanosoma brucei metacaspase MCA2 0.0149 0.0326 0.0618
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0043
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0136 0.0293 0.0789
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0331 0.0809 0.0809
Toxoplasma gondii microneme protein MIC17C 0.003 0.001 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.041 0.1019 0.1019
Echinococcus multilocularis histone deacetylase 3 0.0085 0.0157 0.0157
Trypanosoma brucei Calpain-like protein 1.2 0.0317 0.0773 0.1465
Trypanosoma brucei calpain-like protein, putative 0.1091 0.2829 0.5364
Onchocerca volvulus Slit protein homolog 0.0045 0.005 0.0075
Plasmodium falciparum plasmepsin V 0.0055 0.0077 0.0221
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Toxoplasma gondii histone deacetylase HDAC1 0.0095 0.0184 0.035
Leishmania major calpain family cysteine protease-like protein 0.0317 0.0773 0.1465
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0075 0.013 0.013
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.006 0.006
Onchocerca volvulus 0.0507 0.1279 0.241
Onchocerca volvulus 0.0045 0.005 0.0075
Schistosoma mansoni calpain-7 (C02 family) 0.1095 0.2838 0.2838
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0164 0.0366 0.0694
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Entamoeba histolytica hypothetical protein, conserved 0.0035 0.0024 0.0048
Trypanosoma cruzi centrin, putative 0.017 0.0383 0.0383
Entamoeba histolytica cysteine protease, putative 0.0307 0.0746 0.2398
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0311 0.0311
Plasmodium vivax metacaspase 1, putative 0.0149 0.0326 0.103
Mycobacterium tuberculosis Probable lipase LipD 0.011 0.0222 0.0479
Toxoplasma gondii aspartyl protease 0.0055 0.0077 0.0147
Brugia malayi hypothetical protein 0.0123 0.0259 0.0259
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0165 0.0369 0.1756
Brugia malayi Calcium binding EGF domain containing protein 0.0045 0.005 0.005
Trypanosoma brucei calpain, putative 0.0317 0.0773 0.1465
Mycobacterium leprae Probable lipase LipE 0.011 0.0222 0.1058
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0307 0.0746 0.2046
Echinococcus granulosus protein jagged 1 0.0045 0.005 0.005
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0076 0.0076
Brugia malayi hypothetical protein 0.0042 0.0043 0.0043
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1384 0.3608 0.3608
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.011 0.0222 0.0222
Schistosoma mansoni peroxidasin 0.0507 0.1279 0.1279
Schistosoma mansoni chromatin regulatory protein sir2 0.0136 0.0293 0.0293
Trypanosoma brucei cysteine peptidase, putative 0.0317 0.0773 0.1465
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0064 0.0064
Schistosoma mansoni centrin 0.0163 0.0365 0.0365
Brugia malayi histone deacetylase 11 0.0041 0.004 0.004
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0035 0.0024 0.0048
Schistosoma mansoni histone deacetylase 4 5 0.0095 0.0184 0.0184
Echinococcus granulosus Transglutaminase 0.0318 0.0775 0.0775
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.0282 0.0282
Schistosoma mansoni calpain C (C02 family) 0.1091 0.2829 0.2829
Mycobacterium ulcerans zinc metalloprotease 0.0096 0.0187 0.0891
Giardia lamblia Cathepsin B precursor 0.0307 0.0746 0.2046
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0317 0.0773 0.1465
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0164 0.0366 0.0366
Brugia malayi EGF-like domain containing protein 0.0045 0.005 0.005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.009 0.0429
Plasmodium vivax histone deacetylase 1, putative 0.0085 0.0157 0.0479
Schistosoma mansoni septate junction protein 0.0045 0.005 0.005
Brugia malayi Pre-SET motif family protein 0.01 0.0197 0.0197
Brugia malayi Trypsin family protein 0.0196 0.0451 0.0451
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.0192 0.0192
Brugia malayi Cathepsin L-like precursor 0.1186 0.308 0.308
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0149 0.0326 0.0326
Toxoplasma gondii histone deacetylase HDAC4 0.0041 0.004 0.0076
Trypanosoma cruzi histone deacetylase 1, putative 0.0085 0.0157 0.0157
Toxoplasma gondii cathepsin CPC2 0.0307 0.0746 0.1414
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0197 0.0197
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Leishmania major phospholipase c-like protein 0.0163 0.0365 0.0692
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1091 0.2829 0.2829
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Leishmania major proteasome beta 5 subunit, putative 0.0165 0.0369 0.07
Loa Loa (eye worm) hypothetical protein 0.1828 0.4786 0.4786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Schistosoma mansoni hypothetical protein 0.0034 0.0022 0.0022
Loa Loa (eye worm) proteasome subunit beta type 1 0.0075 0.013 0.013
Schistosoma mansoni Mername-AA248 (C02 family) 0.1091 0.2829 0.2829
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0196 0.0451 0.0451
Echinococcus multilocularis histone deacetylase 8 0.0041 0.004 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0307 0.0746 0.0746
Brugia malayi Kringle domain containing protein 0.0046 0.0053 0.0053
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0121 0.0121
Trypanosoma cruzi histone deacetylase, putative 0.0041 0.004 0.004
Brugia malayi histone deacetylase 3 (HD3) 0.0085 0.0157 0.0157
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0043 0.0043
Plasmodium falciparum serine repeat antigen 2 0.0307 0.0746 0.2398
Loa Loa (eye worm) hypothetical protein 0.0356 0.0877 0.0877
Brugia malayi Cathepsin L-like precursor 0.0829 0.2134 0.2134
Trypanosoma brucei centrin-3 0.017 0.0383 0.0727
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0056 0.0151
Plasmodium vivax vivapain-2 0.1186 0.308 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0829 0.2134 0.5903
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3083 0.8118 0.8118
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1186 0.308 0.308
Echinococcus granulosus intermediate filament protein 0.0054 0.0075 0.0075
Echinococcus granulosus importin subunit beta 1 0.0058 0.0084 0.0084
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0056 0.0056
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0075 0.013 0.013
Loa Loa (eye worm) trypsin family protein 0.0196 0.0451 0.0451
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0048 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.005 0.0064 0.0064
Trichomonas vaginalis calmodulin, putative 0.017 0.0383 0.1039
Giardia lamblia Glycogen phosphorylase 0.0109 0.022 0.0584
Schistosoma mansoni gabp alpha 0.0147 0.0321 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0326 0.0879
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0092
Leishmania major histone deacetylase, putative 0.0085 0.0157 0.0297
Schistosoma mansoni cpg binding protein 0.0059 0.0089 0.0089
Giardia lamblia Cathepsin L precursor 0.0307 0.0746 0.2046
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0573 0.1452 0.2738
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0055 0.0077 0.0077
Onchocerca volvulus 0.0048 0.0058 0.0091
Brugia malayi Fli-1 protein 0.0446 0.1115 0.1115
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1384 0.3608 0.3608
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.005
Schistosoma mansoni gamma-secretase subunit aph-1 0.0252 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0053 0.0072 0.0072
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.001 0.001
Echinococcus granulosus endothelin converting enzyme 1 0.0096 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Brugia malayi beta-lactamase family protein 0.011 0.0222 0.0222
Schistosoma mansoni histone deacetylase 0.0085 0.0157 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0009 0.0018
Brugia malayi cathepsin L-like precursor 0.0829 0.2134 0.2134
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0076 0.0076
Onchocerca volvulus 0.0216 0.0504 0.0939
Onchocerca volvulus Huntingtin homolog 0.0123 0.0259 0.0472
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.0773 0.0773
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0307 0.0746 0.2398
Entamoeba histolytica cysteine proteinase 2 0.0663 0.1692 0.548
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.009 0.009
Plasmodium vivax centrin-1, putative 0.0163 0.0365 0.1157
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0044 0.0044
Loa Loa (eye worm) ctsf protein 0.1186 0.308 0.308
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0365 0.0988
Giardia lamblia Histone deacetylase 0.0085 0.0157 0.0409
Echinococcus multilocularis caspase 2 0.0364 0.0899 0.0899
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1186 0.308 0.8533
Trypanosoma brucei metacaspase MCA3 0.0149 0.0326 0.0618
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0356 0.0877 0.0877
Giardia lamblia Cathepsin L precursor 0.0307 0.0746 0.2046
Trichomonas vaginalis calpain, putative 0.0317 0.0773 0.2121
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3791 1 1
Toxoplasma gondii hypothetical protein 0.003 0.001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0058
Schistosoma mansoni calpain (C02 family) 0.1091 0.2829 0.2829
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.009 0.0171
Echinococcus granulosus histone deacetylase 1 0.0085 0.0157 0.0157
Schistosoma mansoni hypothetical protein 0.0196 0.0451 0.0451
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0053 0.0101
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Echinococcus granulosus cathepsin l1 0.0829 0.2134 0.2134
Trypanosoma brucei centrin, putative 0.0163 0.0365 0.0692
Onchocerca volvulus 0.0045 0.005 0.0075
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Toxoplasma gondii troponin c, isotype gamma, putative 0.0163 0.0365 0.0692
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.006 0.006
Trypanosoma cruzi cysteine proteinase, putative 0.0663 0.1692 0.1692
Echinococcus multilocularis calpain 0.1091 0.2829 0.2829
Onchocerca volvulus 0.0196 0.0451 0.0837
Loa Loa (eye worm) hypothetical protein 0.0026 0.0001 0.0001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.0282 0.0282
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0307 0.0746 0.2046
Trypanosoma brucei Calpain-like protein CALP1.3 0.0317 0.0773 0.1465
Leishmania major metacaspase, putative 0.0149 0.0326 0.0618
Plasmodium vivax hypothetical protein, conserved 0.0149 0.0326 0.103
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0043 0.0043
Trypanosoma cruzi histone deacetylase, putative 0.0095 0.0184 0.0184
Echinococcus multilocularis gamma secretase subunit aph 1 0.0252 0.06 0.06
Plasmodium vivax calpain, putative 0.1091 0.2829 0.9184
Mycobacterium ulcerans transglutaminase family protein 0.0318 0.0775 0.3685
Brugia malayi notch-like transmembrane receptor 0.0045 0.005 0.005
Echinococcus multilocularis cysteine protease 0.1186 0.308 0.308
Schistosoma mansoni glycogen phosphorylase 0.0109 0.022 0.022
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0317 0.0773 0.0773
Echinococcus granulosus cathepsin L 0.0307 0.0746 0.0746
Onchocerca volvulus Peroxidasin homolog 0.0507 0.1279 0.241
Giardia lamblia Cathepsin B precursor 0.0307 0.0746 0.2046
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.1289 0.3353 0.3353
Trichomonas vaginalis calcium binding protein, putative 0.017 0.0383 0.1039
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0307 0.0746 0.2398
Loa Loa (eye worm) hypothetical protein 0.0116 0.0239 0.0239
Onchocerca volvulus Cathepsin L homolog 0.0307 0.0746 0.1397
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.001 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0311 0.0311
Brugia malayi Cathepsin L-like precursor 0.1186 0.308 0.308
Trypanosoma cruzi hypothetical protein, conserved 0.011 0.0222 0.0222
Loa Loa (eye worm) notch protein 0.0045 0.005 0.005
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0058 0.0058
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0096 0.0187 0.0187
Mycobacterium ulcerans esterase/lipase LipP 0.011 0.0222 0.1058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Loa Loa (eye worm) hypothetical protein 0.0181 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0043
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0053 0.0143
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2012 0.5275 1
Schistosoma mansoni cathepsin F (C01 family) 0.1186 0.308 0.308
Trypanosoma brucei hypothetical protein 0.0317 0.0773 0.1465
Giardia lamblia Hypothetical protein 0.0165 0.0371 0.1003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0125 0.0125
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0044 0.0044
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0056 0.0151
Brugia malayi transcriptional regulator, Sir2 family protein 0.0035 0.0024 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0311 0.0311
Echinococcus granulosus cpg binding protein 0.0063 0.0098 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.056 0.1531
Schistosoma mansoni hypothetical protein 0.0196 0.0451 0.0451
Leishmania major cathepsin L-like protease 0.1186 0.308 0.5839
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0043 0.0043
Echinococcus granulosus lamin 0.0054 0.0075 0.0075
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0331 0.0809 0.0809
Brugia malayi MH2 domain containing protein 0.0244 0.058 0.058
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0048 0.006 0.014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0076 0.0076
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0307 0.0746 0.2398
Leishmania major centrin, putative 0.0163 0.0365 0.0692
Brugia malayi beta-lactamase family protein 0.011 0.0222 0.0222
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0196 0.0451 0.0451
Giardia lamblia Hypothetical protein 0.0307 0.0746 0.2046
Mycobacterium leprae conserved hypothetical protein 0.011 0.0222 0.1058
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Schistosoma mansoni ap endonuclease 0.006 0.009 0.009
Brugia malayi hypothetical protein 0.0216 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.0055 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0507 0.1279 0.1279
Leishmania major calpain protease-like protein 0.0317 0.0773 0.1465
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0151 0.0332 0.0896
Loa Loa (eye worm) calpain 5 0.0774 0.1988 0.1988
Loa Loa (eye worm) cysteine protease 0.1186 0.308 0.308
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0311 0.0311
Echinococcus granulosus calpain A 0.1091 0.2829 0.2829
Echinococcus granulosus acylamino acid releasing enzyme 0.0237 0.056 0.056
Entamoeba histolytica Ran family GTPase 0.0042 0.0044 0.0113
Echinococcus multilocularis cpg binding protein 0.0063 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0071 0.0121 0.0121
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0151 0.0332 0.0332
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0055 0.0077 0.0147
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0092
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0142 0.0309 0.0976
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0048 0.006 0.0164
Leishmania major oligopeptidase b 0.0818 0.2102 0.3986
Trypanosoma brucei calmodulin, putative 0.0163 0.0365 0.0692
Echinococcus multilocularis beta LACTamase domain containing family member 0.011 0.0222 0.0222
Plasmodium vivax proteasome subunit beta type-5, putative 0.0165 0.0369 0.1172
Echinococcus granulosus cathepsin L 0.0663 0.1692 0.1692
Loa Loa (eye worm) hypothetical protein 0.0163 0.0365 0.0365
Entamoeba histolytica prolyl oligopeptidase family protein 0.0237 0.056 0.1794
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Loa Loa (eye worm) hypothetical protein 0.0307 0.0746 0.0746
Echinococcus granulosus protein jagged 2 0.0045 0.005 0.005
Mycobacterium tuberculosis Conserved protein 0.0318 0.0775 0.1668
Schistosoma mansoni calmodulin related calcium binding protein 0.0163 0.0365 0.0365
Onchocerca volvulus 0.0055 0.0077 0.0128
Trypanosoma cruzi oligopeptidase b 0.0818 0.2102 0.2102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0307 0.0746 0.2046
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.024 0.0455
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0932 0.2407 0.2407
Entamoeba histolytica cysteine protease, putative 0.0663 0.1692 0.548
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0035 0.0024 0.0024
Schistosoma mansoni cathepsin F (C01 family) 0.0829 0.2134 0.2134
Leishmania major GTP-binding protein, putative 0.0042 0.0044 0.0083
Brugia malayi hypothetical protein 0.0042 0.0043 0.0043
Brugia malayi Animal haem peroxidase family protein 0.0507 0.1279 0.1279
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.001 0.0019
Trichomonas vaginalis penicillin-binding protein, putative 0.011 0.0222 0.0592
Leishmania major i/6 autoantigen-like protein 0.0163 0.0365 0.0692
Mycobacterium leprae Conserved hypothetical protein 0.0318 0.0775 0.3685
Brugia malayi cathepsin Z-like cysteine proteinase 0.0307 0.0746 0.0746
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0317 0.0773 0.2121
Loa Loa (eye worm) hypothetical protein 0.0073 0.0125 0.0125
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0043 0.0043
Plasmodium vivax aspartyl protease, putative 0.0055 0.0077 0.0221
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0296 0.0718 0.0718
Loa Loa (eye worm) hypothetical protein 0.006 0.0091 0.0091
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0008 0.0008
Plasmodium falciparum plasmepsin VI 0.0055 0.0077 0.0221
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Plasmodium falciparum centrin-1 0.0163 0.0365 0.1157
Mycobacterium leprae probable zinc metalloprotease 0.0096 0.0187 0.0891
Schistosoma mansoni reticulocalbin 0.0163 0.0365 0.0365
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Echinococcus multilocularis cathepsin b 0.3791 1 1
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.022 0.022
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0035 0.0024 0.0024
Trypanosoma cruzi prolyl endopeptidase 0.2012 0.5275 0.5275
Trichomonas vaginalis centrin, putative 0.0163 0.0365 0.0988
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0035 0.0024 0.0024
Giardia lamblia Cathepsin B precursor 0.0307 0.0746 0.2046
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.009 0.0263
Loa Loa (eye worm) hypothetical protein 0.011 0.0222 0.0222
Plasmodium vivax serine-repeat antigen (SERA) 0.0307 0.0746 0.2398
Echinococcus granulosus glycogen phosphorylase 0.0109 0.022 0.022
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0043 0.0043
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0035 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0829 0.2134 0.2134
Schistosoma mansoni cathepsin D (A01 family) 0.0356 0.0877 0.0877
Trichomonas vaginalis ap endonuclease, putative 0.006 0.009 0.0225
Plasmodium vivax serine-repeat antigen (SERA) 0.0307 0.0746 0.2398
Brugia malayi cathepsin F-like cysteine proteinase 0.0356 0.0877 0.0877
Brugia malayi Angiotensin-converting enzyme family protein 0.3235 0.8523 0.8523
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.005
Echinococcus granulosus protein jagged 2 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.2012 0.5275 0.5275
Mycobacterium ulcerans Sir2-like regulatory protein 0.0035 0.0024 0.0115
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0149 0.0326 0.0618
Loa Loa (eye worm) hypothetical protein 0.0364 0.0899 0.0899
Giardia lamblia Cathepsin B precursor 0.1384 0.3608 1
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0055 0.0077 0.0077
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0181 0.0413 0.0413
Echinococcus multilocularis musashi 0.0054 0.0075 0.0075
Plasmodium vivax hypothetical protein, conserved 0.011 0.0222 0.0693
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0055 0.0077 0.0077
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0121 0.0121
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1091 0.2829 0.2829
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0043 0.0043
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0035 0.0024 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0196 0.0451 0.0451
Plasmodium vivax hypothetical protein, conserved 0.0237 0.056 0.1794
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0043 0.0043
Onchocerca volvulus 0.1186 0.308 0.5831
Brugia malayi PAN domain containing protein 0.003 0.001 0.001
Onchocerca volvulus Deterin homolog 0.0181 0.0413 0.0764
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0092
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.0773
Plasmodium vivax hypothetical protein, conserved 0.0165 0.0371 0.1176
Onchocerca volvulus 0.1186 0.308 0.5831
Echinococcus granulosus histone deacetylase 6 0.0095 0.0184 0.0184
Entamoeba histolytica prolyl oligopeptidase family protein 0.0237 0.056 0.1794
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0163 0.0365 0.0365
Echinococcus granulosus expressed protein 0.0817 0.2101 0.2101
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.3235 0.8523 0.8523
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0307 0.0746 0.2398
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0043 0.0043
Brugia malayi Muscle positioning protein 4 0.0045 0.005 0.005
Echinococcus granulosus caspase 3 0.0148 0.0323 0.0323
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0165 0.0369 0.07
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.0282 0.0607
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.0773 0.0773
Echinococcus granulosus Mastin 0.0196 0.0451 0.0451
Loa Loa (eye worm) transcriptional regulator 0.0035 0.0024 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0196 0.0451 0.0451
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0064 0.0064
Giardia lamblia Alanyl dipeptidyl peptidase 0.0237 0.056 0.1531
Entamoeba histolytica hypothetical protein, conserved 0.0237 0.056 0.1794
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0096 0.0187 0.0187
Leishmania major cytochrome p450-like protein 0.0054 0.0074 0.014
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0307 0.0746 0.0746
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1091 0.2829 0.2829
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0136 0.0293 0.0556
Mycobacterium tuberculosis Probable conserved lipoprotein 0.011 0.0222 0.0479
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0181 0.0413 0.0413
Echinococcus granulosus enteropeptidase 0.0196 0.0451 0.0451
Echinococcus granulosus gamma secretase subunit aph 1 0.0252 0.06 0.06
Echinococcus multilocularis cysteine protease 0.1186 0.308 0.308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1289 0.3353 0.6357
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0136 0.0293 0.0924
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2012 0.5275 0.5275
Toxoplasma gondii cathepsin CPL 0.1186 0.308 0.5839
Trypanosoma cruzi major cysteine proteinase, putative 0.0307 0.0746 0.0746
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.009 0.5
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0043 0.0043
Schistosoma mansoni calmodulin 0.0163 0.0365 0.0365
Giardia lamblia Cysteine protease 0.0307 0.0746 0.2046
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0048 0.006 0.006
Brugia malayi hypothetical protein 0.0055 0.0077 0.0077
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0237 0.056 0.1794
Echinococcus multilocularis Mastin 0.0196 0.0451 0.0451
Onchocerca volvulus Dual oxidase homolog 0.0507 0.1279 0.241
Brugia malayi hypothetical protein 0.0165 0.037 0.037
Echinococcus multilocularis glycoprotein Antigen 5 0.0196 0.0451 0.0451
Leishmania major calmodulin, putative 0.0163 0.0365 0.0692
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.0282 0.1342
Toxoplasma gondii histone deacetylase HDAC5 0.0041 0.0041 0.0077
Echinococcus granulosus neurogenic locus notch protein 4 0.0045 0.005 0.005
Echinococcus multilocularis hypothetical protein 0.1091 0.2829 0.2829
Onchocerca volvulus 0.1186 0.308 0.5831
Trichomonas vaginalis calmodulin, putative 0.0163 0.0365 0.0988
Schistosoma mansoni hypothetical protein 0.0046 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1186 0.308 0.8533
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.001 0.001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0307 0.0746 0.0746
Loa Loa (eye worm) Notch2 0.0045 0.005 0.005
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.009 0.0263
Brugia malayi cathepsin Z-like cysteine proteinase 0.0307 0.0746 0.0746
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0818 0.2102 1
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0181 0.0413 0.0413
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1091 0.2829 0.5364
Plasmodium falciparum importin beta, putative 0.0058 0.0084 0.0244
Brugia malayi Delta serrate ligand family protein 0.0045 0.005 0.005
Echinococcus multilocularis cathepsin b 0.3791 1 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0317 0.0773 0.0773
Trichomonas vaginalis calcium binding protein, putative 0.0163 0.0365 0.0988
Trypanosoma brucei prolyl endopeptidase 0.2012 0.5275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1384 0.3608 1
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0163 0.0365 0.0988
Plasmodium vivax histone deacetylase 2, putative 0.0095 0.0184 0.057
Trichomonas vaginalis calcium binding proteins, putative 0.0163 0.0365 0.0988
Echinococcus multilocularis histone deacetylase 0.0095 0.0184 0.0184
Brugia malayi Cathepsin L-like precursor 0.1186 0.308 0.308
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0063 0.0063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0317 0.0773 0.1465
Trypanosoma brucei Aph-1 protein, putative 0.0098 0.0192 0.0364
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0307 0.0746 0.2046
Echinococcus granulosus EF hand domain containing family member A2 0.0163 0.0365 0.0365
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0044 0.0083
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0149 0.0326 0.0879
Loa Loa (eye worm) transcriptional regulator 0.0136 0.0293 0.0293
Echinococcus granulosus prolyl endopeptidase 0.2012 0.5275 0.5275
Trypanosoma cruzi cysteine peptidase, putative 0.0356 0.0877 0.0877

Activities

Activity type Activity value Assay description Source Reference
RBA (binding) = 1 Binding affinity of the compound to estrogen receptor ChEMBL. 2544725

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.