Detailed information for compound 52858

Basic information

Technical information
  • TDR Targets ID: 52858
  • Name: 3,4-dihydro-2H-1,4-benzothiazine-5,7-dicarbox ylic acid
  • MW: 239.248 | Formula: C10H9NO4S
  • H donors: 3 H acceptors: 4 LogP: 1.24 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1cc2SCCNc2c(c1)C(=O)O
  • InChi: 1S/C10H9NO4S/c12-9(13)5-3-6(10(14)15)8-7(4-5)16-2-1-11-8/h3-4,11H,1-2H2,(H,12,13)(H,14,15)
  • InChiKey: SJTWJXKXVIKTRK-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus apoptotic protease activating factor 1 0.014 0.0492 0.0492
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0479 0.1848 0.1848
Brugia malayi Thioredoxin family protein 0.0211 0.0775 0.0775
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0089 0.0287 0.0287
Trichomonas vaginalis calcineurin B subunit, putative 0.0123 0.0423 0.1162
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.019 0.0691 0.0691
Echinococcus granulosus baculoviral IAP repeat containing protein 0.019 0.0691 0.0691
Trichomonas vaginalis calcineurin B subunit, putative 0.0121 0.0415 0.1138
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0601 0.2337 0.2337
Echinococcus granulosus dnaJ subfamily B 0.0439 0.1688 0.1688
Echinococcus multilocularis cathepsin L 0.0479 0.1848 0.1848
Echinococcus granulosus flap endonuclease 1 0.0026 0.0034 0.0034
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0024 0.0024 0.0024
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0084 0.0114
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0121 0.0415 0.056
Leishmania major cathepsin L-like protease 0.0863 0.3385 0.4567
Entamoeba histolytica cysteine protease, putative 0.0217 0.08 0.2362
Echinococcus granulosus enteropeptidase 0.0107 0.0359 0.0359
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Plasmodium vivax aspartyl protease, putative 0.0019 0.0005 0.0013
Echinococcus multilocularis tumor protein p63 0.0372 0.1419 0.1419
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.022 0.0812 0.2228
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Schistosoma mansoni microtubule-associated protein tau 0.1519 0.6011 0.6011
Giardia lamblia Cathepsin B precursor 0.0217 0.08 0.2193
Brugia malayi regulator of G-protein signaling rgs-7 0.0042 0.0099 0.0099
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0099 0.0099
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.007 0.007
Brugia malayi Cathepsin L-like precursor 0.0863 0.3385 0.3385
Entamoeba histolytica calcium-binding protein, putative 0.0121 0.0415 0.1225
Echinococcus granulosus cathepsin b 0.2515 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0307 0.0307
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.0365 0.1078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0863 0.3385 0.3385
Trypanosoma cruzi C-8 sterol isomerase, putative 0.036 0.1371 0.1371
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0075
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0019 0.0019
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1932 0.7666 0.7666
Trypanosoma brucei caltractin, putative 0.0125 0.0429 0.0579
Loa Loa (eye worm) hypothetical protein 0.036 0.1371 0.1371
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0099 0.0099
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0102 0.028
Loa Loa (eye worm) hypothetical protein 0.0601 0.2337 0.2337
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0217 0.08 0.2362
Echinococcus granulosus prolyl endopeptidase 0.1869 0.7412 0.7412
Plasmodium vivax aspartyl protease, putative 0.0019 0.0005 0.0013
Brugia malayi Protein kinase domain containing protein 0.0046 0.0115 0.0115
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0104 0.0346 0.1021
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0102 0.0102
Echinococcus multilocularis calpain 7 (C02 family) 0.0751 0.2939 0.2939
Entamoeba histolytica calmodulin, putative 0.0121 0.0415 0.1225
Echinococcus granulosus peroxidasin 0.0065 0.0189 0.0189
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0462 0.0623
Echinococcus multilocularis neurocalcin 0.0121 0.0415 0.0415
Loa Loa (eye worm) zinc metallopeptidase 4 0.0024 0.0024 0.0024
Echinococcus granulosus inhibitor of apoptosis protein 0.019 0.0691 0.0691
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0102 0.0138
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Loa Loa (eye worm) prolyl oligopeptidase 0.0347 0.1318 0.1318
Toxoplasma gondii EF hand domain-containing protein 0.0121 0.0415 0.056
Trypanosoma brucei cysteine peptidase C (CPC) 0.0928 0.3645 0.4918
Loa Loa (eye worm) hypothetical protein 0.0096 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Loa Loa (eye worm) fibroinase 0.0863 0.3385 0.3385
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0217 0.08 0.08
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0217 0.08 0.08
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0217 0.08 0.2362
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2126 0.8444 0.8444
Plasmodium vivax unspecified product 0.0479 0.1848 0.5459
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.007 0.007
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.08 0.2194
Brugia malayi hypothetical protein 0.0065 0.0189 0.0189
Onchocerca volvulus Glycogen phosphorylase homolog 0.0109 0.0365 0.0492
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Echinococcus granulosus glycogen phosphorylase 0.0109 0.0365 0.0365
Trypanosoma brucei calpain, putative 0.022 0.0812 0.1095
Echinococcus multilocularis gamma secretase subunit aph 1 0.0252 0.094 0.094
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0104 0.0346 0.0949
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0018 0 0.0001
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0104 0.0346 0.0949
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.08 0.2194
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0307 0.0307
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0217 0.08 0.2362
Brugia malayi Papain family cysteine protease containing protein 0.0217 0.08 0.08
Echinococcus multilocularis expressed protein 0.0821 0.3219 0.3219
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0099 0.0099
Entamoeba histolytica calpain family cysteine protease, putative 0.022 0.0812 0.2398
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Brugia malayi A-kinase anchor protein 10, precursor 0.0042 0.0099 0.0099
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Plasmodium falciparum proteasome subunit beta type-5 0.0089 0.0287 0.0848
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Loa Loa (eye worm) hypothetical protein 0.0262 0.0978 0.0978
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0075
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0089 0.0287 0.0388
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0121 0.0415 0.1225
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0189 0.0189
Brugia malayi Papain family cysteine protease containing protein 0.0479 0.1848 0.1848
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Entamoeba histolytica calpain large subunit domain III containing protein 0.0531 0.2057 0.6075
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0084 0.0249
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.022 0.0812 0.0812
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0844 0.3311 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0075 0.0075
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0019 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0347 0.1318 0.3892
Echinococcus multilocularis cathepsin L cysteine protease 0.0863 0.3385 0.3385
Trichomonas vaginalis hypothetical protein 0.022 0.0812 0.2228
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0184 0.0666 0.0666
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.022 0.0812 0.0812
Echinococcus granulosus caspase 8 0.0017 0.000000023181 0.000000023181
Entamoeba histolytica cysteine protease, putative 0.0863 0.3385 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0347 0.1318 0.3892
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0217 0.08 0.2194
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0217 0.08 0.2362
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0217 0.08 0.2194
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Onchocerca volvulus 0.0863 0.3385 0.4567
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0462 0.0623
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0217 0.08 0.08
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0019 0.0019
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Brugia malayi Papain family cysteine protease containing protein 0.0479 0.1848 0.1848
Brugia malayi Flap endonuclease-1 0.0026 0.0034 0.0034
Trypanosoma cruzi conserved protein 0.022 0.0812 0.0812
Echinococcus multilocularis dnaJ subfamily B 0.0439 0.1688 0.1688
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0217 0.08 0.2194
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0189 0.0189
Schistosoma mansoni cathepsin F (C01 family) 0.0601 0.2337 0.2337
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.0365 0.0365
Mycobacterium tuberculosis Conserved hypothetical protein 0.0211 0.0775 0.1285
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Entamoeba histolytica cysteine proteinase 2 0.0479 0.1848 0.5458
Schistosoma mansoni hypothetical protein 0.0121 0.0415 0.0415
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.0324 0.0324
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0019 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0928 0.3645 1
Toxoplasma gondii centrin, putative 0.0121 0.0415 0.056
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.0365 0.1002
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0217 0.08 0.2362
Echinococcus granulosus glycoprotein Antigen 5 0.0107 0.0359 0.0359
Entamoeba histolytica grainin 2 0.0125 0.0429 0.1267
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0054 0.0054
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0075 0.0207
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Schistosoma mansoni flap endonuclease-1 0.0023 0.0024 0.0024
Trichomonas vaginalis calpain, putative 0.022 0.0812 0.2228
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0019 0.0019
Brugia malayi aspartic protease BmAsp-1, identical 0.0019 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Brugia malayi ecdysteroid receptor 0.0022 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.007 0.021
Schistosoma mansoni ef hand domain family member A2 0.0121 0.0415 0.0415
Brugia malayi cathepsin Z-like cysteine proteinase 0.0217 0.08 0.08
Loa Loa (eye worm) calpain family protein 1 0.2005 0.7959 0.7959
Echinococcus granulosus Glycosyl transferase family 35 0.0109 0.0365 0.0365
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0928 0.3645 0.4918
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0075 0.0207
Onchocerca volvulus Cathepsin L homolog 0.0863 0.3385 0.4567
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0084 0.0084
Giardia lamblia Glycogen phosphorylase 0.0109 0.0365 0.1001
Loa Loa (eye worm) hypothetical protein 0.019 0.0691 0.0691
Entamoeba histolytica calmodulin, putative 0.0121 0.0415 0.1225
Leishmania major calpain protease-like protein 0.022 0.0812 0.1095
Echinococcus multilocularis programmed cell death protein 0.0125 0.0429 0.0429
Mycobacterium leprae Conserved hypothetical protein 0.0211 0.0775 0.2339
Giardia lamblia Cathepsin B precursor 0.0217 0.08 0.2193
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0089 0.0287 0.0848
Brugia malayi Papain family cysteine protease containing protein 0.0863 0.3385 0.3385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Loa Loa (eye worm) calmodulin-like protein 0.0121 0.0415 0.0415
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0054 0.0148 0.0148
Trypanosoma brucei protein I/6 0.0121 0.0415 0.056
Echinococcus granulosus calpain 0.0751 0.2939 0.2939
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Brugia malayi proteasome subunit beta type 2 0.0043 0.0102 0.0102
Toxoplasma gondii aspartyl protease ASP1 0.0019 0.0005 0.0006
Leishmania major calmodulin-like protein 0.0121 0.0415 0.056
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0863 0.3385 0.3385
Echinococcus multilocularis caspase 8 0.0017 0.000000023181 0.000000023181
Brugia malayi Cathepsin L-like precursor 0.0863 0.3385 0.3385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0415 0.1138
Giardia lamblia Hypothetical protein 0.0211 0.0775 0.2124
Trypanosoma cruzi cysteine peptidase, putative 0.0966 0.38 0.38
Onchocerca volvulus 0.0863 0.3385 0.4567
Brugia malayi Pepsin A precursor 0.0019 0.0005 0.0005
Giardia lamblia Alanyl dipeptidyl peptidase 0.0347 0.1318 0.3614
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0415 0.1138
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0208 0.028
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0121 0.0415 0.0415
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0018 0 0.0001
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0189 0.0189
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0097 0.0317 0.0317
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0019 0.0019
Brugia malayi Peptidase family M13 containing protein 0.0097 0.0317 0.0317
Mycobacterium leprae Conserved hypothetical protein 0.0211 0.0775 0.2339
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0102 0.0102
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.123 0.4854 0.6549
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0099 0.0099
Onchocerca volvulus 0.0863 0.3385 0.4567
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0863 0.3385 0.9287
Schistosoma mansoni hypothetical protein 0.019 0.0691 0.0691
Onchocerca volvulus 0.0036 0.0075 0.0101
Onchocerca volvulus 0.0863 0.3385 0.4567
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0097 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0046 0.0115 0.0115
Trypanosoma cruzi major cysteine proteinase, putative 0.0217 0.08 0.08
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0104 0.0346 0.1021
Echinococcus multilocularis programmed cell death protein 0.0125 0.0429 0.0429
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0104 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Schistosoma mansoni peroxidasin 0.0065 0.0189 0.0189
Schistosoma mansoni coup transcription factor 0.0022 0.0019 0.0019
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0084 0.0231
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0208 0.0208
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0075 0.0075
Trichomonas vaginalis calpain, putative 0.022 0.0812 0.2228
Toxoplasma gondii hypothetical protein 0.003 0.0049 0.0067
Echinococcus multilocularis calmodulin 0.0121 0.0415 0.0415
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0104 0.0346 0.0346
Giardia lamblia Cysteine protease 0.0217 0.08 0.2193
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0189 0.0189
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0049
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0189 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0019 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0751 0.2939 0.2939
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0089 0.0287 0.0476
Loa Loa (eye worm) hypothetical protein 0.0347 0.1318 0.1318
Onchocerca volvulus 0.0022 0.0019 0.0025
Echinococcus multilocularis calmodulin 0.0121 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0262 0.0978 0.0978
Echinococcus multilocularis Dipeptidyl peptidase 9 0.123 0.4854 0.4854
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0751 0.2939 0.2939
Brugia malayi Calmodulin-like protein 0.0121 0.0415 0.0415
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Mycobacterium leprae Probable lipase LipE 0.0036 0.0075 0.0227
Schistosoma mansoni mitochondrial solute carrier 0.0121 0.0415 0.0415
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0084 0.5
Echinococcus granulosus calbindin 32 0.0123 0.0423 0.0423
Entamoeba histolytica prolyl oligopeptidase family protein 0.0347 0.1318 0.3892
Brugia malayi Cytochrome P450 family protein 0.0035 0.007 0.007
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0075 0.0102
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0075 0.0125
Brugia malayi Cathepsin L-like precursor 0.0863 0.3385 0.3385
Onchocerca volvulus 0.0107 0.0359 0.0484
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2515 1 1
Entamoeba histolytica grainin, putative 0.0123 0.0423 0.125
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0089 0.0287 0.0287
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0034 0.0099
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0123 0.0423 0.0423
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Echinococcus granulosus Mastin 0.0107 0.0359 0.0359
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.2939
Onchocerca volvulus 0.0019 0.0005 0.0006
Echinococcus granulosus tissue type plasminogen activator 0.0046 0.0115 0.0115
Echinococcus multilocularis Regulator of G protein signaling 20 0.0042 0.0099 0.0099
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0189 0.0255
Brugia malayi cathepsin L-like precursor 0.0601 0.2337 0.2337
Giardia lamblia Encystation-specific protease 0.0217 0.08 0.2193
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0208 0.0208
Trypanosoma brucei centrin-3 0.0125 0.0429 0.0579
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0347 0.1318 0.3892
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0102 0.028
Brugia malayi Cathepsin L-like precursor 0.0262 0.0978 0.0978
Schistosoma mansoni calpain-2 (C02 family) 0.022 0.0812 0.0812
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0121 0.0415 0.1138
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0049
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0099 0.0099
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0 0.0001
Plasmodium falciparum plasmepsin VII 0.0019 0.0005 0.0013
Onchocerca volvulus Cathepsin L homolog 0.0863 0.3385 0.4567
Schistosoma mansoni caspase-7 (C14 family) 0.0158 0.0562 0.0562
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0071 0.0216 0.0216
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0042 0.0099 0.0099
Schistosoma mansoni cathepsin F (C01 family) 0.0863 0.3385 0.3385
Schistosoma mansoni peroxidasin 0.0065 0.0189 0.0189
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0844 0.3311 0.3311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0217 0.08 0.2362
Leishmania major cysteine peptidase A (CPA) 0.0863 0.3385 0.4567
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0084 0.0084
Trypanosoma cruzi centrin-3 0.0125 0.0429 0.0429
Brugia malayi ERG2 and Sigma1 receptor like protein 0.036 0.1371 0.1371
Onchocerca volvulus 0.003 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Echinococcus multilocularis endothelin converting enzyme 1 0.0097 0.0317 0.0317
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0019 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0751 0.2939 0.2939
Onchocerca volvulus 0.0121 0.0415 0.0559
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Plasmodium falciparum plasmepsin VIII, putative 0.0019 0.0005 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0966 0.38 0.38
Toxoplasma gondii cathepsin CPC1 0.0217 0.08 0.1079
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0601 0.2337 0.6411
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0217 0.08 0.2194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0019 0.0019
Entamoeba histolytica cysteine proteinase, putative 0.0479 0.1848 0.5458
Echinococcus granulosus programmed cell death protein 0.0125 0.0429 0.0429
Trichomonas vaginalis centrin, putative 0.0121 0.0415 0.1138
Toxoplasma gondii hypothetical protein 0.003 0.0049 0.0067
Echinococcus multilocularis calpain family protein 1, d 0.1474 0.5832 0.5832
Entamoeba histolytica glycogen phosphorylase, putative 0.0109 0.0365 0.1078
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0347 0.1318 0.1318
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0019 0.0019
Onchocerca volvulus 0.003 0.0049 0.0066
Loa Loa (eye worm) calpain family protein 1 0.1474 0.5832 0.5832
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2515 1 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.022 0.0812 0.1095
Trypanosoma cruzi cysteine protease, putative 0.0479 0.1848 0.1848
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0684 0.2671 0.2671
Onchocerca volvulus 0.0107 0.0359 0.0484
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Brugia malayi Papain family cysteine protease containing protein 0.0217 0.08 0.08
Trypanosoma brucei prolyl endopeptidase 0.1869 0.7412 1
Onchocerca volvulus 0.0046 0.0115 0.0154
Toxoplasma gondii calcium-dependent protein kinase 0.0123 0.0423 0.0571
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Echinococcus granulosus glycogen phosphorylase 0.0109 0.0365 0.0365
Brugia malayi Proteasome A-type and B-type family protein 0.0089 0.0287 0.0287
Trypanosoma brucei I/6 autoantigen 0.0121 0.0415 0.056
Schistosoma mansoni gamma-secretase subunit aph-1 0.0252 0.094 0.094
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.022 0.0812 0.1095
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0217 0.08 0.2194
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0018 0 0.0001
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0097 0.0317 0.0317
Entamoeba histolytica cysteine proteinase, putative 0.0601 0.2337 0.6903
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0075 0.0075
Entamoeba histolytica cysteine proteinase, putative 0.0479 0.1848 0.5458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0479 0.1848 0.2493
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0928 0.3645 0.3645
Schistosoma mansoni hypothetical protein 0.0211 0.0775 0.0775
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.022 0.0812 0.2228
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0005 0.0013
Echinococcus granulosus EF hand domain containing family member A2 0.0121 0.0415 0.0415
Brugia malayi Trypsin family protein 0.0107 0.0359 0.0359
Trypanosoma cruzi Aph-1 protein, putative 0.0098 0.0324 0.0324
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0019 0.0019
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0018 0 0.0001
Brugia malayi Serine protease Z688.6 precursor 0.0104 0.0346 0.0346
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1869 0.7412 0.7412
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Echinococcus multilocularis cathepsin b 0.2515 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0099 0.0099
Toxoplasma gondii hypothetical protein 0.022 0.0812 0.1095
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.2939
Trypanosoma brucei Calpain-like protein 1.1 0.022 0.0812 0.1095
Toxoplasma gondii microneme protein, putative 0.003 0.0049 0.0067
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0217 0.08 0.08
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Loa Loa (eye worm) TK/ROR protein kinase 0.0046 0.0115 0.0115
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0217 0.08 0.2193
Brugia malayi PXA domain containing protein 0.0042 0.0099 0.0099
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0089 0.0287 0.0788
Loa Loa (eye worm) hypothetical protein 0.1785 0.7077 0.7077
Echinococcus multilocularis survival motor neuron protein 1 0.0257 0.0959 0.0959
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.123 0.4854 0.6549
Giardia lamblia Cysteine protease 0.0217 0.08 0.2193
Plasmodium falciparum calpain 0.022 0.0812 0.2399
Echinococcus granulosus calpain A 0.2128 0.8452 0.8452
Brugia malayi Cytochrome P450 family protein 0.0035 0.007 0.007
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0034 0.0092
Entamoeba histolytica glycogenphosphorylase, putative 0.0047 0.0118 0.0348
Onchocerca volvulus 0.0863 0.3385 0.4567
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Echinococcus granulosus centrin 2 0.0121 0.0415 0.0415
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0019 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Giardia lamblia Cathepsin B precursor 0.0217 0.08 0.2193
Leishmania major calpain family cysteine protease-like protein 0.022 0.0812 0.1095
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0115 0.0115
Leishmania major cytochrome p450-like protein 0.0035 0.007 0.0094
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0034 0.0045
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0462 0.0766
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0217 0.08 0.2362
Loa Loa (eye worm) hypothetical protein 0.0073 0.0223 0.0223
Brugia malayi Trypsin-like protease protein 5 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0067
Onchocerca volvulus 0.003 0.0049 0.0066
Onchocerca volvulus 0.0107 0.0359 0.0484
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0102 0.0301
Loa Loa (eye worm) hypothetical protein 0.0121 0.0415 0.0415
Brugia malayi calpain 5 0.0531 0.2057 0.2057
Schistosoma mansoni Mername-AA248 (C02 family) 0.0751 0.2939 0.2939
Onchocerca volvulus 0.0166 0.0596 0.0804
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Mycobacterium leprae probable zinc metalloprotease 0.0097 0.0317 0.0956
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0346
Toxoplasma gondii calmodulin CAM1 0.0123 0.0423 0.0571
Echinococcus granulosus cysteine protease 0.0479 0.1848 0.1848
Echinococcus multilocularis Transglutaminase 0.0211 0.0775 0.0775
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0024 0.0024
Brugia malayi Cytochrome P450 family protein 0.0058 0.0161 0.0161
Echinococcus granulosus calpain A 0.0751 0.2939 0.2939
Trypanosoma brucei calpain-like protein, putative 0.0751 0.2939 0.3965
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.3965
Brugia malayi Serine carboxypeptidase S28 family protein 0.0104 0.0346 0.0346
Entamoeba histolytica cysteine proteinase, putative 0.0479 0.1848 0.5458
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0121 0.0415 0.0415
Plasmodium vivax hypothetical protein, conserved 0.0347 0.1318 0.3892
Toxoplasma gondii EFHC1, putative 0.0121 0.0415 0.056
Schistosoma mansoni hypothetical protein 0.022 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0217 0.08 0.08
Schistosoma mansoni glycogen phosphorylase 0.0047 0.0118 0.0118
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Leishmania major centrin, putative,caltractin, putative 0.0121 0.0415 0.056
Trichomonas vaginalis calmodulin, putative 0.0123 0.0423 0.1162
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0024 0.0024
Brugia malayi EF hand family protein 0.0121 0.0415 0.0415
Brugia malayi Blistered cuticle protein 3 0.0065 0.0189 0.0189
Trypanosoma cruzi oligopeptidase b 0.0844 0.3311 0.3311
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0307 0.0307
Brugia malayi Angiotensin-converting enzyme family protein 0.0605 0.2353 0.2353
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Onchocerca volvulus 0.003 0.0049 0.0066
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0189 0.0189
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0019 0.0019
Trypanosoma brucei calmodulin, putative 0.0123 0.0423 0.0571
Echinococcus multilocularis cpg binding protein 0.0033 0.0061 0.0061
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.007 0.007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0313 0.0313
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0018 0 0.0001
Toxoplasma gondii 1,3(4)-beta-glucanase 0.003 0.0049 0.0067
Echinococcus multilocularis cathepsin b 0.2515 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0217 0.08 0.2194
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0067
Echinococcus granulosus calpain 5 0.0751 0.2939 0.2939
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0415 0.0415
Giardia lamblia Hypothetical protein 0.0217 0.08 0.2193
Onchocerca volvulus 0.0863 0.3385 0.4567
Brugia malayi prolyl oligopeptidase family protein 0.1869 0.7412 0.7412
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.123 0.4854 0.4854
Plasmodium falciparum serine repeat antigen 2 0.0217 0.08 0.2362
Onchocerca volvulus 0.0104 0.0346 0.0466
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.022 0.0812 0.2228
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.019 0.0691 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0272
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0104 0.0346 0.0346
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0084 0.014
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0084 0.0232
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Giardia lamblia Cathepsin B precursor 0.0928 0.3645 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0216 0.0216
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0252 0.094 0.094
Onchocerca volvulus Prolyl endopeptidase homolog 0.1869 0.7412 1
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0104 0.0346 0.1021
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Plasmodium falciparum cysteine proteinase falcipain 3 0.0863 0.3385 1
Entamoeba histolytica hypothetical protein 0.0217 0.08 0.2362
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0415 0.1138
Onchocerca volvulus 0.0107 0.0359 0.0484
Onchocerca volvulus Cathepsin L homolog 0.0217 0.08 0.1079
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0019 0.0019
Onchocerca volvulus 0.003 0.0049 0.0066
Brugia malayi EF hand family protein 0.0123 0.0423 0.0423
Echinococcus granulosus acylamino acid releasing enzyme 0.0347 0.1318 0.1318
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0121 0.0415 0.1226
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0208 0.0613
Onchocerca volvulus 0.0065 0.0189 0.0255
Schistosoma mansoni centrin-related 0.0121 0.0415 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0346 0.0949
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0019 0.0005 0.0005
Schistosoma mansoni calpain-7 (C02 family) 0.0754 0.2951 0.2951
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0019 0.0005 0.0005
Echinococcus multilocularis calpain A 0.2128 0.8452 0.8452
Trypanosoma brucei antigen, putative 0.0751 0.2939 0.3965
Loa Loa (eye worm) hypothetical protein 0.0097 0.0317 0.0317
Giardia lamblia Cathepsin L precursor 0.0217 0.08 0.2193
Brugia malayi Cathepsin L-like precursor 0.0863 0.3385 0.3385
Plasmodium falciparum serine repeat antigen 1 0.0217 0.08 0.2362
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0415 0.1138
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0121 0.0415 0.0415
Leishmania major phospholipase c-like protein 0.0121 0.0415 0.056
Brugia malayi proteasome subunit beta type 1 0.0069 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0024 0.0024 0.0024
Brugia malayi hypothetical protein 0.0166 0.0596 0.0596
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0844 0.3311 0.4467
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0019 0.0019
Schistosoma mansoni reticulocalbin 0.0123 0.0423 0.0423
Leishmania major hypothetical protein, conserved 0.0123 0.0423 0.0571
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0462 0.0462
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0863 0.3385 0.9287
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Brugia malayi prolyl oligopeptidase family protein 0.123 0.4854 0.4854
Echinococcus multilocularis prolyl endopeptidase 0.1869 0.7412 0.7412
Brugia malayi Peroxidasin 0.0065 0.0189 0.0189
Schistosoma mansoni hypothetical protein 0.0052 0.014 0.014
Schistosoma mansoni hypothetical protein 0.0121 0.0415 0.0415
Trypanosoma cruzi caltractin, putative 0.0121 0.0415 0.0415
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0121 0.0415 0.056
Trichomonas vaginalis calmodulin, putative 0.0125 0.0429 0.1177
Loa Loa (eye worm) calpain D 0.022 0.0812 0.0812
Loa Loa (eye worm) EF hand family protein 0.0121 0.0415 0.0415
Loa Loa (eye worm) cysteine protease 0.0863 0.3385 0.3385
Echinococcus granulosus neuronal calcium sensor 0.0121 0.0415 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0084 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0123 0.0423 0.0423
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0075 0.0125
Loa Loa (eye worm) hypothetical protein 0.0217 0.08 0.08
Entamoeba histolytica cysteine proteinase 1, putative 0.0479 0.1848 0.5458
Toxoplasma gondii microneme protein MIC4 0.003 0.0049 0.0067
Loa Loa (eye worm) hypothetical protein 0.0073 0.0223 0.0223
Trypanosoma cruzi cysteine peptidase, putative 0.0262 0.0978 0.0978
Loa Loa (eye worm) hypothetical protein 0.1254 0.495 0.495
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0018 0 0.0001
Schistosoma mansoni endothelin-converting enzyme-related 0.0024 0.0024 0.0024
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.0005 0.0013
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0042 0.0099 0.0099
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0462 0.0462
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0019 0.0019
Onchocerca volvulus 0.0048 0.0122 0.0164
Brugia malayi beta-lactamase family protein 0.0036 0.0075 0.0075
Echinococcus granulosus Dipeptidyl peptidase 9 0.123 0.4854 0.4854
Trypanosoma brucei calpain-like protein, putative 0.0751 0.2939 0.3965
Plasmodium falciparum serine repeat antigen 8 0.0217 0.08 0.2362
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Loa Loa (eye worm) CYP4Cod1 0.0035 0.007 0.007
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0844 0.3311 0.4467
Trypanosoma cruzi calmodulin, putative 0.0121 0.0415 0.0415
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.123 0.4854 0.6549
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0751 0.2939 0.3965
Mycobacterium tuberculosis Conserved protein 0.0036 0.0075 0.0125
Echinococcus granulosus cathepsin L 0.0217 0.08 0.08
Trypanosoma brucei Calpain-like protein 1.2 0.022 0.0812 0.1095
Brugia malayi calpain family protein 1 0.2005 0.7959 0.7959
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0049
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0019 0.0019
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0121 0.0415 0.0415
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0863 0.3385 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0751 0.2939 0.2939
Trichomonas vaginalis centrin, putative 0.0121 0.0415 0.1138
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0019 0.0005 0.0006
Brugia malayi PXA domain containing protein 0.0042 0.0099 0.0099
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0206 0.0206
Onchocerca volvulus 0.0036 0.0075 0.0101
Toxoplasma gondii troponin c, isotype gamma, putative 0.0121 0.0415 0.056
Plasmodium vivax plasmepsin V, putative 0.0019 0.0005 0.0013
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0084 0.0114
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Brugia malayi beta-lactamase 0.0036 0.0075 0.0075
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0018 0 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.0042 0.0099 0.0099
Loa Loa (eye worm) RGS-3 protein 0.0042 0.0099 0.0099
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0844 0.3311 0.3311
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.022 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0217 0.08 0.08
Brugia malayi Trypsin family protein 0.0107 0.0359 0.0359
Toxoplasma gondii subtilisin SUB12 0.003 0.0049 0.0067
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0018 0 0.0001
Giardia lamblia Cathepsin L precursor 0.0217 0.08 0.2193
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0272
Trypanosoma brucei centrin, putative 0.0121 0.0415 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0272
Loa Loa (eye worm) cathepsin B 0.0928 0.3645 0.3645
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0075 0.0125
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0089 0.0287 0.0867
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0075 0.0125
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Mycobacterium tuberculosis Probable peptidase 0.0844 0.3311 0.5496
Trypanosoma cruzi calpain cysteine peptidase, putative 0.022 0.0812 0.0812
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1602 0.6344 0.6344
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.08 0.2194
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0107 0.0359 0.0359
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0121 0.0415 0.1225
Onchocerca volvulus 0.0065 0.0189 0.0255
Loa Loa (eye worm) glycogen phosphorylase 0.0109 0.0365 0.0365
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0018 0 0.0001
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0217 0.08 0.08
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0118 0.0348
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.019 0.0691 0.0691
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0189 0.0189
Mycobacterium ulcerans proteasome PrcB 0.0089 0.0287 0.0867
Onchocerca volvulus 0.003 0.0049 0.0066
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.1474 0.5832 0.5832
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0019 0.0019
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0019 0.0019
Echinococcus multilocularis enteropeptidase 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0048 0.0122 0.0122
Schistosoma mansoni memapsin-2 (A01 family) 0.0463 0.1784 0.1784
Toxoplasma gondii prolyl endopeptidase 0.1869 0.7412 1
Leishmania major cathepsin L-like protease 0.0863 0.3385 0.4567
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.022 0.0812 0.0812
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0102 0.0138
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0019 0.0005 0.0012
Echinococcus granulosus EF HAND 1 calcium binding site 0.0121 0.0415 0.0415
Echinococcus granulosus cpg binding protein 0.0033 0.0061 0.0061
Echinococcus granulosus calcium uptake protein 1 0.0123 0.0423 0.0423
Onchocerca volvulus 0.0036 0.0075 0.0101
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0412 0.0412
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0189 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0019 0.0019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0462 0.1394
Trypanosoma brucei Calpain-like protein CALP1.3 0.022 0.0812 0.1095
Brugia malayi hypothetical protein 0.0019 0.0005 0.0005
Trypanosoma brucei centrin, putative 0.0121 0.0415 0.056
Toxoplasma gondii cathepsin B 0.0928 0.3645 0.4918
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Schistosoma mansoni neprilysin-2 (M13 family) 0.0049 0.0125 0.0125
Brugia malayi steroid hormone receptor 0.0022 0.0019 0.0019
Giardia lamblia Cathepsin L precursor 0.0217 0.08 0.2193
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0018 0 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0089 0.0287 0.0287
Echinococcus multilocularis proteasome (prosome, macropain) 0.0089 0.0287 0.0287
Echinococcus multilocularis regulator of G protein signaling 3 0.0042 0.0099 0.0099
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0462 0.1394
Trypanosoma brucei oligopeptidase b 0.0844 0.3311 0.4467
Giardia lamblia Alanyl dipeptidyl peptidase 0.0347 0.1318 0.3614
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Mycobacterium tuberculosis Conserved protein 0.0211 0.0775 0.1285
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0161 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0217 0.08 0.2194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.08 0.2194
Plasmodium falciparum serine repeat antigen 5 0.0217 0.08 0.2362
Brugia malayi hypothetical protein 0.014 0.0492 0.0492
Brugia malayi Eukaryotic aspartyl protease family protein 0.0019 0.0005 0.0005
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0208 0.0208
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0049 0.0125 0.0125
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0863 0.3385 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.3965
Leishmania major programmed cell death 6 protein-like protein 0.0121 0.0415 0.056
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0415 0.0415
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Trypanosoma brucei mitochondrial calcium uptake 1 0.0121 0.0415 0.056
Echinococcus granulosus cathepsin l1 0.0601 0.2337 0.2337
Schistosoma mansoni calpain-7 (C02 family) 0.0754 0.2951 0.2951
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0019 0.0019
Mycobacterium ulcerans putative transglutaminase-like protein 0.0211 0.0775 0.2339
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.022 0.0812 0.0812
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0189 0.0255
Plasmodium falciparum serine repeat antigen 4 0.0217 0.08 0.2362
Giardia lamblia Cathepsin L precursor 0.0217 0.08 0.2193
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0019 0.0019
Echinococcus multilocularis calbindin 32 0.0123 0.0423 0.0423
Plasmodium falciparum serine repeat antigen 7 0.0217 0.08 0.2362
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0178 0.024
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0067
Plasmodium falciparum cysteine proteinase falcipain 1 0.0479 0.1848 0.5459
Echinococcus multilocularis Mastin 0.0107 0.0359 0.0359
Toxoplasma gondii ABC1 family protein 0.0036 0.0075 0.0102
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0346
Brugia malayi gamma-secretase subunit aph-1 0.0252 0.094 0.094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Leishmania major proteasome beta 5 subunit, putative 0.0089 0.0287 0.0388
Mycobacterium tuberculosis Hypothetical protein 0.0211 0.0775 0.1285
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Loa Loa (eye worm) hypothetical protein 0.0071 0.0216 0.0216
Trypanosoma cruzi calmodulin, putative 0.0121 0.0415 0.0415
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0019 0.0005 0.0005
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0217 0.08 0.2362
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2515 1 1
Brugia malayi beta-lactamase family protein 0.0036 0.0075 0.0075
Leishmania major oligopeptidase b 0.0844 0.3311 0.4467
Onchocerca volvulus 0.0031 0.0054 0.0072
Toxoplasma gondii aspartyl protease 0.0019 0.0005 0.0006
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0121 0.0415 0.0415
Brugia malayi prolyl oligopeptidase family protein 0.0347 0.1318 0.1318
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0099 0.0099
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0099 0.0099
Trypanosoma brucei calpain-like protein, putative 0.0751 0.2939 0.3965
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0019 0.0019
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0121 0.0415 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.1848 0.5069
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0121 0.0415 0.0415
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.123 0.4854 0.4854
Trypanosoma cruzi calmodulin, putative 0.0121 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0479 0.1848 0.2493
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.123 0.4854 0.4854
Echinococcus granulosus endothelin converting enzyme 1 0.0097 0.0317 0.0317
Plasmodium vivax proteasome subunit beta type-5, putative 0.0089 0.0287 0.0848
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1602 0.6344 0.6344
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0272
Onchocerca volvulus 0.0211 0.0775 0.1045
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0104 0.0346 0.0467
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0462 0.0462
Leishmania major C-8 sterol isomerase-like protein 0.036 0.1371 0.1849
Loa Loa (eye worm) hypothetical protein 0.0071 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0257 0.0959 0.0959
Onchocerca volvulus 0.019 0.0691 0.0932
Onchocerca volvulus 0.0107 0.0359 0.0484
Entamoeba histolytica prolyl oligopeptidase family protein 0.0347 0.1318 0.3892
Schistosoma mansoni cathepsin S (C01 family) 0.0217 0.08 0.08
Plasmodium falciparum plasmepsin III 0.0019 0.0005 0.0013
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1869 0.7412 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0019 0.0019
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0313 0.0313
Onchocerca volvulus 0.0065 0.0189 0.0255
Giardia lamblia Transglutaminase/protease, putative 0.0211 0.0775 0.2124
Trypanosoma cruzi centrin, putative 0.0125 0.0429 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0347 0.1318 0.3615
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0018 0 0.0001
Leishmania major calcineurin B subunit, putative 0.0121 0.0415 0.056
Echinococcus multilocularis cathepsin L 0.0217 0.08 0.08
Loa Loa (eye worm) PXA domain-containing protein 0.0042 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0346
Echinococcus multilocularis calpain 0.0751 0.2939 0.2939
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0024 0.0024 0.0024
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0217 0.08 0.08
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Schistosoma mansoni axis inhibition protein axin 0.0042 0.0099 0.0099
Schistosoma mansoni glycogen phosphorylase 0.0109 0.0365 0.0365
Echinococcus granulosus transmembrane protease serine 3 0.0107 0.0359 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.08 0.2194
Brugia malayi Cathepsin L-like precursor 0.0601 0.2337 0.2337
Giardia lamblia Hypothetical protein 0.0123 0.0423 0.1161
Schistosoma mansoni calmodulin related calcium binding protein 0.0121 0.0415 0.0415
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0347 0.1318 0.3892
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0104 0.0346 0.0346
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0189 0.0189
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0462 0.0462
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0019 0.0019
Onchocerca volvulus 0.014 0.0492 0.0663
Onchocerca volvulus 0.003 0.0049 0.0066
Plasmodium vivax centrin-1, putative 0.0121 0.0415 0.1226
Giardia lamblia Cathepsin B precursor 0.0928 0.3645 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0479 0.1848 0.1848
Trypanosoma cruzi oligopeptidase b 0.0844 0.3311 0.3311
Mycobacterium tuberculosis Conserved hypothetical protein 0.0211 0.0775 0.1285
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0075
Trypanosoma brucei calpain-like protein, putative 0.0751 0.2939 0.3965
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0067
Onchocerca volvulus Cell death protein 3 homolog 0.0158 0.0562 0.0758
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0034 0.0045
Echinococcus multilocularis neuronal calcium sensor 0.0121 0.0415 0.0415
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0479 0.1848 0.1848
Leishmania major centrin, putative 0.0121 0.0415 0.056
Plasmodium vivax proteasome subunit beta type-6, putative 0.0018 0 0.0001
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Entamoeba histolytica hypothetical protein, conserved 0.0123 0.0423 0.125
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.007 0.007
Trypanosoma brucei cytochrome P450, putative 0.0035 0.007 0.0094
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0 0.0001
Schistosoma mansoni hypothetical protein 0.0107 0.0359 0.0359
Echinococcus multilocularis EF hand domain containing family member A2 0.0123 0.0423 0.0423
Trichomonas vaginalis glycogen phosphorylase, putative 0.0109 0.0365 0.1002
Leishmania major calmodulin, putative 0.0121 0.0415 0.056
Mycobacterium ulcerans zinc metalloprotease 0.0097 0.0317 0.0956
Brugia malayi programmed cell death protein 6 0.0121 0.0415 0.0415
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0019 0.0019
Trichomonas vaginalis myosin light chain 1, putative 0.0121 0.0415 0.1138
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0099 0.0099
Echinococcus multilocularis inhibitor of apoptosis protein 0.019 0.0691 0.0691
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0104 0.0346 0.0346
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0084 0.0084
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0031 0.0031
Echinococcus multilocularis transmembrane protease serine 3 0.0107 0.0359 0.0359
Onchocerca volvulus Peroxidase homolog 0.0065 0.0189 0.0255
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0075 0.0125
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0347 0.1318 0.3615
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.2939
Echinococcus multilocularis caspase 2 0.0158 0.0562 0.0562
Brugia malayi Serine protease Z688.6 precursor 0.0104 0.0346 0.0346
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0019 0.0019
Onchocerca volvulus 0.1254 0.495 0.6678
Echinococcus multilocularis cysteine protease 0.0863 0.3385 0.3385
Onchocerca volvulus 0.0121 0.0415 0.0559
Leishmania major cathepsin L-like protease 0.0966 0.38 0.5126
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0217 0.08 0.2362
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.014 0.014
Trypanosoma cruzi kinesin, putative 0.0531 0.2057 0.2057
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0018 0 0.0001
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Toxoplasma gondii proteasome subunit beta type, putative 0.0089 0.0287 0.0388
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0217 0.08 0.2362
Leishmania major centrin, putative 0.0121 0.0415 0.056
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0217 0.08 0.2194
Brugia malayi aspartic protease BmAsp-2, identical 0.0019 0.0005 0.0005
Brugia malayi Trypsin family protein 0.0107 0.0359 0.0359
Plasmodium vivax proteasome subunit beta type-7, putative 0.0018 0 0.0001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.022 0.0812 0.2228
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0073 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0073 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.022 0.0812 0.0812
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.022 0.0812 0.0812
Trypanosoma cruzi kinesin, putative 0.0531 0.2057 0.2057
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0097 0.0317 0.0525
Echinococcus multilocularis regulator of G protein signaling 0.0042 0.0099 0.0099
Giardia lamblia Cathepsin L-like protease 0.0217 0.08 0.2193
Entamoeba histolytica cysteine proteinase, putative 0.0863 0.3385 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0075
Plasmodium falciparum plasmepsin X 0.0019 0.0005 0.0013
Giardia lamblia Serine peptidase, putative 0.0104 0.0346 0.0948
Onchocerca volvulus 0.003 0.0049 0.0066
Echinococcus multilocularis glycogen phosphorylase 0.0109 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Schistosoma mansoni cathepsin F (C01 family) 0.0863 0.3385 0.3385
Leishmania major hypothetical protein, conserved 0.0121 0.0415 0.056
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0844 0.3311 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0217 0.08 0.1079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.08 0.2194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0863 0.3385 0.9287
Schistosoma mansoni rab 0.0121 0.0415 0.0415
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.019 0.0691 0.0691
Entamoeba histolytica calcium binding family protein 0.0121 0.0415 0.1225
Plasmodium vivax serine-repeat antigen (SERA) 0.0217 0.08 0.2362
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1522 0.6025 1
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.08 0.2194
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0075 0.0227
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0347 0.1318 0.1778
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2515 1 1
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0019 0.0019
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0705 0.2752 0.2752
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0307 0.0307
Brugia malayi peptidase family M13 containing protein 0.0024 0.0024 0.0024
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0019 0.0019
Onchocerca volvulus 0.0123 0.0423 0.0571
Trypanosoma brucei hypothetical protein, conserved 0.0121 0.0415 0.056
Echinococcus multilocularis microtubule associated protein 2 0.1519 0.6011 0.6011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0601 0.2337 0.6411
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0217 0.08 0.2194
Leishmania major cathepsin L-like protease 0.0863 0.3385 0.4567
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0099 0.0099
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0107 0.0359 0.0359
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0099 0.0099
Entamoeba histolytica cysteine protease, putative 0.0217 0.08 0.2362
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0217 0.08 0.08
Schistosoma mansoni z-protein (S1r protein) 0.0042 0.0099 0.0099
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Echinococcus multilocularis acylamino acid releasing enzyme 0.0347 0.1318 0.1318
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2126 0.8444 0.8444
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0049
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0019 0.0025
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0121 0.0415 0.1138
Mycobacterium ulcerans hypothetical protein 0.0036 0.0075 0.0227
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Mycobacterium ulcerans hypothetical protein 0.0211 0.0775 0.2339
Echinococcus multilocularis tissue type plasminogen activator 0.0046 0.0115 0.0115
Loa Loa (eye worm) ctsf protein 0.0863 0.3385 0.3385
Giardia lamblia Cathepsin B precursor 0.0217 0.08 0.2193
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.3965
Echinococcus multilocularis glycoprotein Antigen 5 0.0107 0.0359 0.0359
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Trichomonas vaginalis peptide N-glycanase, putative 0.0211 0.0775 0.2125
Toxoplasma gondii kringle domain-containing protein 0.0046 0.0115 0.0155
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0034 0.0034
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0217 0.08 0.2362
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0217 0.08 0.2193
Toxoplasma gondii cathepsin CPC2 0.0217 0.08 0.1079
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0262 0.0978 0.0978
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0313 0.0313
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0307 0.0307
Loa Loa (eye worm) programmed cell death protein 6 0.0123 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0071 0.0216 0.0216
Schistosoma mansoni calpain C (C02 family) 0.0751 0.2939 0.2939
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Brugia malayi cathepsin F-like cysteine proteinase 0.0262 0.0978 0.0978
Mycobacterium tuberculosis Conserved protein 0.0036 0.0075 0.0125
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.2939
Plasmodium vivax proteasome subunit beta type-3, putative 0.0018 0 0.0001
Chlamydia trachomatis glycogen phosphorylase 0.0109 0.0365 0.5
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.022 0.0812 0.1095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0217 0.08 0.08
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Trypanosoma brucei calpain, putative 0.022 0.0812 0.1095
Onchocerca volvulus 0.0217 0.08 0.1079
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.022 0.0812 0.0812
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Loa Loa (eye worm) prolyl oligopeptidase 0.1602 0.6344 0.6344
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0049 0.0125 0.0125
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1602 0.6344 0.6344
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0099 0.0099
Onchocerca volvulus 0.0107 0.0359 0.0484
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0663 0.2584 0.2584
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0208 0.0569
Trypanosoma brucei C-8 sterol isomerase, putative 0.036 0.1371 0.1849
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.0005 0.0005
Echinococcus granulosus expressed protein 0.0821 0.3219 0.3219
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.022 0.0812 0.0812
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0019 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0346 0.0949
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0751 0.2939 0.3965
Plasmodium vivax aspartyl protease, putative 0.0019 0.0005 0.0013
Echinococcus granulosus calpain 7 C02 family 0.0751 0.2939 0.2939
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2126 0.8444 0.8444
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0307 0.0307
Trypanosoma brucei calmodulin, putative 0.0121 0.0415 0.056
Onchocerca volvulus 0.0096 0.0313 0.0422
Brugia malayi nuclear receptor NHR-88 0.0022 0.0019 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0102 0.0301
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0121 0.0415 0.0415
Mycobacterium tuberculosis Conserved protein 0.0036 0.0075 0.0125
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0019 0.0005 0.0005
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1932 0.7666 0.7666
Plasmodium vivax calpain, putative 0.0751 0.2939 0.8681
Loa Loa (eye worm) aspartyl protease 6 0.0019 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Onchocerca volvulus 0.003 0.0049 0.0066
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0272
Onchocerca volvulus 0.0863 0.3385 0.4567
Echinococcus granulosus survival motor neuron protein 1 0.0257 0.0959 0.0959
Schistosoma mansoni neprilysin 0.0025 0.0031 0.0031
Giardia lamblia Cysteine protease 0.0217 0.08 0.2193
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0217 0.08 0.2362
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0415 0.1138
Leishmania major i/6 autoantigen-like protein 0.0121 0.0415 0.056
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0892 0.3501 0.4723
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Plasmodium vivax unspecified product 0.0262 0.0978 0.289
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.022 0.0812 0.2228
Brugia malayi calcium-binding protein 0.0121 0.0415 0.0415
Entamoeba histolytica cysteine proteinase, putative 0.0863 0.3385 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Brugia malayi prolyl oligopeptidase family protein 0.1602 0.6344 0.6344
Giardia lamblia Cathepsin B precursor 0.0217 0.08 0.2193
Onchocerca volvulus 0.0052 0.014 0.0189
Mycobacterium ulcerans transglutaminase family protein 0.0211 0.0775 0.2339
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0107 0.0359 0.0359
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0102 0.0102
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0099 0.0099
Brugia malayi Cell death protein 3 precursor 0.0158 0.0562 0.0562
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0005
Brugia malayi cathepsin Z-like cysteine proteinase 0.0217 0.08 0.08
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0148 0.0148
Toxoplasma gondii microneme protein MIC17B 0.003 0.0049 0.0067
Loa Loa (eye worm) hypothetical protein 0.0863 0.3385 0.3385
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0019 0.0019
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Echinococcus granulosus regulator of G protein signaling 7 0.0042 0.0099 0.0099
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0189 0.0189
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0107 0.0359 0.0359
Echinococcus multilocularis EF hand domain containing family member A2 0.0121 0.0415 0.0415
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2005 0.7959 0.7959
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0042 0.0099 0.0099
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0084 0.0232
Schistosoma mansoni hypothetical protein 0.0046 0.0115 0.0115
Giardia lamblia Cysteine protease 0.0217 0.08 0.2193
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0847 0.332 0.332
Brugia malayi hypothetical protein 0.0042 0.0099 0.0099
Toxoplasma gondii hypothetical protein 0.0347 0.1318 0.1778
Entamoeba histolytica hypothetical protein 0.0042 0.0099 0.0292
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0034 0.0092
Loa Loa (eye worm) hypothetical protein 0.0158 0.0562 0.0562
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0208 0.0569
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Plasmodium falciparum centrin-1 0.0121 0.0415 0.1226
Loa Loa (eye worm) hypothetical protein 0.0097 0.0317 0.0317
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0075 0.0125
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0217 0.08 0.08
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0067
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0296 0.0296
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0019 0.0019
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0018 0 0.0001
Brugia malayi Cathepsin L-like cysteine proteinase 0.0601 0.2337 0.2337
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0104 0.0346 0.0346
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Trypanosoma cruzi I/6 autoantigen, putative 0.0121 0.0415 0.0415
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0042 0.0099 0.0099
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0018 0 0.0001
Echinococcus multilocularis calcium uptake protein 1 0.0123 0.0423 0.0423
Trichomonas vaginalis set domain proteins, putative 0.0754 0.295 0.8092
Echinococcus multilocularis apoptotic protease activating factor 1 0.014 0.0492 0.0492
Schistosoma mansoni cpg binding protein 0.0033 0.0061 0.0061
Brugia malayi hypothetical protein 0.0257 0.0959 0.0959
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1602 0.6344 0.8558
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1932 0.7666 0.7666
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0208 0.0208
Toxoplasma gondii microneme protein MIC17A 0.003 0.0049 0.0067
Echinococcus multilocularis cysteine protease 0.0863 0.3385 0.3385
Leishmania major calmodulin-like protein 0.0121 0.0415 0.056
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0928 0.3645 0.3645
Echinococcus multilocularis regulator of G protein signaling 7 0.0042 0.0099 0.0099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0019 0.0019
Plasmodium falciparum peptidase, putative 0.0347 0.1318 0.3892
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0313 0.0313
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0075 0.0075
Trichomonas vaginalis esterase, putative 0.0036 0.0075 0.0207
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0347 0.1318 0.1778
Onchocerca volvulus 0.0601 0.2337 0.3153
Brugia malayi prolyl oligopeptidase family protein 0.0347 0.1318 0.1318
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0075 0.0075
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0019 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0019 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.0321 0.1214 0.1214
Entamoeba histolytica cysteine protease, putative 0.0217 0.08 0.2362
Loa Loa (eye worm) hypothetical protein 0.0545 0.2113 0.2113
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0262 0.0978 0.0978
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0479 0.1848 0.1848
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.022 0.0812 0.1095
Schistosoma mansoni cathepsin C 0.0217 0.08 0.08
Schistosoma mansoni calpain (C02 family) 0.0751 0.2939 0.2939
Echinococcus granulosus cathepsin b 0.2515 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0217 0.08 0.2194
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0089 0.0287 0.0787
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0099
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Loa Loa (eye worm) beta-lactamase 0.0036 0.0075 0.0075
Mycobacterium ulcerans hypothetical protein 0.0211 0.0775 0.2339
Plasmodium falciparum plasmepsin II 0.0019 0.0005 0.0013
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0217 0.08 0.2194
Brugia malayi calpain 5 0.022 0.0812 0.0812
Brugia malayi calpain D 0.022 0.0812 0.0812
Brugia malayi hypothetical protein 0.0545 0.2113 0.2113
Plasmodium falciparum plasmepsin IV 0.0019 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.2005 0.7959 0.7959
Echinococcus granulosus EF hand domain containing family member A2 0.0123 0.0423 0.0423
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0217 0.08 0.08
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0415 0.0415
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0019 0.0019
Brugia malayi Cathepsin L-like precursor 0.0863 0.3385 0.3385
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0 0.0001
Schistosoma mansoni ap endonuclease 0.0039 0.0084 0.0084
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0034 0.01
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0084 0.0084
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Echinococcus granulosus calmodulin 0.0121 0.0415 0.0415
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0073 0.0223 0.0223
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0042 0.0099 0.0272
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.014 0.0492 0.0492
Onchocerca volvulus 0.0054 0.0148 0.0199
Brugia malayi hypothetical protein 0.0107 0.0359 0.0359
Plasmodium falciparum serine repeat antigen 9 0.0217 0.08 0.2362
Trypanosoma brucei hypothetical protein 0.022 0.0812 0.1095
Leishmania major hypothetical protein, conserved 0.022 0.0812 0.1095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0313 0.0313
Loa Loa (eye worm) trypsin family protein 0.0107 0.0359 0.0359
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.0966 0.38 0.5126
Echinococcus granulosus Transglutaminase 0.0211 0.0775 0.0775
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0844 0.3311 0.5496
Toxoplasma gondii centrin 0.0121 0.0415 0.056
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0075 0.0227
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0307 0.0307
Echinococcus granulosus cathepsin L 0.0479 0.1848 0.1848
Brugia malayi fibroinase precursor 0.0217 0.08 0.08
Mycobacterium ulcerans lipase LipD 0.0036 0.0075 0.0227
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0313 0.0422
Loa Loa (eye worm) hypothetical protein 0.0601 0.2337 0.2337
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0019 0.0019
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2515 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0217 0.08 0.2194
Echinococcus multilocularis centrin 2 0.0121 0.0415 0.0415
Entamoeba histolytica hypothetical protein 0.0042 0.0099 0.0292
Trypanosoma cruzi cruzipain precursor, putative 0.0966 0.38 0.38
Trichomonas vaginalis calcium binding protein, putative 0.0125 0.0429 0.1177
Schistosoma mansoni cathepsin s 0.0262 0.0978 0.0978
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0217 0.08 0.2362
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0102 0.0138
Schistosoma mansoni reticulocalbin 0.0121 0.0415 0.0415
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0018 0 0.0001
Toxoplasma gondii peptidase family M13 protein 0.0097 0.0317 0.0427
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0099 0.0099
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Echinococcus granulosus cathepsin L cysteine protease 0.0479 0.1848 0.1848
Loa Loa (eye worm) hypothetical protein 0.0217 0.08 0.08
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Schistosoma mansoni glycogen phosphorylase 0.0109 0.0365 0.0365
Echinococcus multilocularis calpain 5 0.0751 0.2939 0.2939
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0102 0.0301
Leishmania major hypothetical protein, unknown function 0.022 0.0812 0.1095
Mycobacterium tuberculosis Long conserved protein 0.0211 0.0775 0.1285
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0208 0.0612
Onchocerca volvulus Deterin homolog 0.019 0.0691 0.0932
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0019 0.0019
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0217 0.08 0.2193
Plasmodium falciparum plasmepsin I 0.0019 0.0005 0.0013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0217 0.08 0.08
Plasmodium falciparum flap endonuclease 1 0.0026 0.0034 0.01
Loa Loa (eye worm) calpain 0.0751 0.2939 0.2939
Giardia lamblia Thymus-specific serine protease precursor 0.0104 0.0346 0.0948
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0017 0.000000023181 0.000000023181
Mycobacterium ulcerans beta-lactamase 0.0036 0.0075 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0019 0.0019
Brugia malayi Regulator of G protein signaling domain containing protein 0.0042 0.0099 0.0099
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0121 0.0415 0.0415
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0217 0.08 0.2362
Giardia lamblia Cathepsin L precursor 0.0217 0.08 0.2193
Brugia malayi nuclear hormone receptor 0.0022 0.0019 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0075 0.0207
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0084 0.0249
Entamoeba histolytica cysteine proteinase, putative 0.0479 0.1848 0.5458
Schistosoma mansoni calmodulin 0.0121 0.0415 0.0415
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.1318 0.1318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Brugia malayi MH2 domain containing protein 0.012 0.0412 0.0412
Plasmodium falciparum serine repeat antigen 3 0.0217 0.08 0.2362
Entamoeba histolytica glycogen phosphorylase, putative 0.0047 0.0118 0.0348
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Plasmodium vivax vivapain-2 0.0863 0.3385 1
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Trichomonas vaginalis conserved hypothetical protein 0.022 0.0812 0.2228
Plasmodium vivax SET domain protein, putative 0.0096 0.0313 0.0925
Plasmodium vivax plasmepsin IV, putative 0.0019 0.0005 0.0013
Toxoplasma gondii PAN domain-containing protein 0.003 0.0049 0.0067
Leishmania major cathepsin L-like protease 0.0863 0.3385 0.4567
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Brugia malayi cathepsin F-like cysteine proteinase 0.0217 0.08 0.08
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0208 0.028
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0313 0.0313
Leishmania major calmodulin, putative 0.0121 0.0415 0.056
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0208 0.0613
Echinococcus multilocularis calumenin 0.0123 0.0423 0.0423
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0019 0.0019
Loa Loa (eye worm) PAN domain-containing protein 0.003 0.0049 0.0049
Brugia malayi regulator of G-protein signaling egl-10 0.0042 0.0099 0.0099
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0075 0.0207
Loa Loa (eye worm) hypothetical protein 0.0217 0.08 0.08
Onchocerca volvulus 0.0019 0.0005 0.0006
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0217 0.08 0.08
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0216 0.0216
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0104 0.0346 0.0949
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Trichomonas vaginalis calpain, putative 0.022 0.0812 0.2228
Onchocerca volvulus Peroxidase homolog 0.0065 0.0189 0.0255
Onchocerca volvulus Cathepsin F homolog 0.0863 0.3385 0.4567
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.022 0.0812 0.0812
Plasmodium falciparum plasmepsin IX 0.0019 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Toxoplasma gondii aspartyl protease ASP3 0.0019 0.0005 0.0006
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0099 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0307 0.0307
Giardia lamblia Cathepsin L-like protease 0.0217 0.08 0.2193
Echinococcus granulosus proteasome prosome macropain 0.0089 0.0287 0.0287
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0019 0.0019
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0099 0.0099
Plasmodium falciparum cysteine repeat modular protein 1 0.0046 0.0115 0.0339
Plasmodium vivax vivapain-1 0.0479 0.1848 0.5459
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0 0.0001
Loa Loa (eye worm) calpain 5 0.0531 0.2057 0.2057
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0046 0.0115 0.0339
Brugia malayi PAN domain containing protein 0.003 0.0049 0.0049
Trypanosoma brucei Component of motile flagella 41 0.0121 0.0415 0.056
Loa Loa (eye worm) hypothetical protein 0.1869 0.7412 0.7412
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0084 0.0249
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0605 0.2353 0.2353
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Toxoplasma gondii exonuclease III APE 0.0039 0.0084 0.0114
Schistosoma mansoni cpg binding protein 0.0031 0.0054 0.0054
Mycobacterium ulcerans hypothetical protein 0.0107 0.0359 0.1083
Loa Loa (eye worm) hypothetical protein 0.2515 1 1
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0075 0.0223
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0019 0.0019
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0415 0.0415
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Brugia malayi Cathepsin L-like precursor 0.0601 0.2337 0.2337
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0075 0.0075
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0751 0.2939 0.2939
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0047 0.0118 0.0196
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0189 0.0255
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0347 0.1318 0.3615
Schistosoma mansoni hypothetical protein 0.0439 0.1688 0.1688
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Trypanosoma cruzi cysteine peptidase, putative 0.0863 0.3385 0.3385
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Loa Loa (eye worm) hypothetical protein 0.0073 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Toxoplasma gondii microneme protein MIC17C 0.003 0.0049 0.0067
Schistosoma mansoni centrin 0.0121 0.0415 0.0415
Giardia lamblia Cathepsin B precursor 0.0928 0.3645 1
Trypanosoma brucei Aph-1 protein, putative 0.0098 0.0324 0.0437
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0217 0.08 0.08
Plasmodium vivax proteasome subunit beta type-4, putative 0.0018 0 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0217 0.08 0.08
Leishmania major hypothetical protein, conserved 0.0036 0.0075 0.0102
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.0859 0.1425
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Entamoeba histolytica cysteine protease, putative 0.0479 0.1848 0.5458
Schistosoma mansoni ap endonuclease 0.0039 0.0084 0.0084
Onchocerca volvulus 0.003 0.0049 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.0479 0.1848 0.1848
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0863 0.3385 0.3385
Brugia malayi calpain family protein 1 0.2005 0.7959 0.7959
Entamoeba histolytica cysteine protease, putative 0.0217 0.08 0.2362
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0104 0.0346 0.0346
Schistosoma mansoni cpg binding protein 0.0033 0.0061 0.0061
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0099 0.0099
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0462 0.1394
Trypanosoma brucei Calpain-like protein 2 0.022 0.0812 0.1095
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0049 0.0125 0.0125
Plasmodium vivax unspecified product 0.0217 0.08 0.2362
Trypanosoma cruzi cysteine peptidase, putative 0.0966 0.38 0.38
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0018 0 0.0001
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0018 0 0.0001
Brugia malayi calpain 7 0.0751 0.2939 0.2939
Plasmodium vivax serine-repeat antigen (SERA) 0.0217 0.08 0.2362
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0102 0.0102
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0019 0.0019
Brugia malayi carbohydrate phosphorylase 0.0109 0.0365 0.0365
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0751 0.2939 0.2939
Plasmodium falciparum plasmepsin V 0.0019 0.0005 0.0013
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0099 0.0099
Schistosoma mansoni cathepsin B (C01 family) 0.0217 0.08 0.08
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0272
Plasmodium falciparum plasmepsin VI 0.0019 0.0005 0.0013
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0084 0.0254
Giardia lamblia Hypothetical protein 0.0217 0.08 0.2193
Loa Loa (eye worm) hypothetical protein 0.0166 0.0596 0.0596
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2126 0.8444 0.8444
Trypanosoma cruzi prolyl endopeptidase 0.1869 0.7412 0.7412
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0034 0.0045
Trichomonas vaginalis calcium binding proteins, putative 0.0121 0.0415 0.1138
Trypanosoma cruzi I/6 autoantigen, putative 0.0121 0.0415 0.0415
Schistosoma mansoni hypothetical protein 0.0025 0.0031 0.0031
Echinococcus multilocularis Glycosyl transferase, family 35 0.0109 0.0365 0.0365
Trypanosoma cruzi cysteine proteinase, putative 0.0479 0.1848 0.1848
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.0046 0.0115 0.0155
Trichomonas vaginalis calmodulin-2, putative 0.0121 0.0415 0.1138
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0042 0.0099 0.0099
Echinococcus granulosus neurocalcin 0.0121 0.0415 0.0415
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0208 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0018 0 0.0001
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1869 0.7412 0.7412
Brugia malayi hypothetical protein 0.0042 0.0099 0.0099
Brugia malayi hypothetical protein 0.0019 0.0005 0.0005
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0099 0.0099
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0412 0.0412
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0084 0.0084
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0217 0.08 0.2193
Trypanosoma cruzi cruzipain precursor, putative 0.0262 0.0978 0.0978
Entamoeba histolytica hypothetical protein 0.0042 0.0099 0.0292
Echinococcus multilocularis cathepsin L cysteine protease 0.0863 0.3385 0.3385
Echinococcus granulosus Regulator of G protein signaling 20 0.0042 0.0099 0.0099
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0863 0.3385 0.3385
Brugia malayi cathepsin L precursor 0.0217 0.08 0.08
Plasmodium vivax vivapain-2 0.0863 0.3385 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.1848 0.5069
Schistosoma mansoni hypothetical protein 0.0107 0.0359 0.0359
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0102 0.0279
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0019 0.0019
Leishmania major protein kinase, putative 0.0121 0.0415 0.056
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0104 0.0346 0.0949
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0019 0.0005 0.0006
Trichomonas vaginalis calmodulin, putative 0.0121 0.0415 0.1138
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0019 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.0107 0.0359 0.0359
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0347 0.1318 0.1318
Brugia malayi Cathepsin L-like precursor 0.0863 0.3385 0.3385
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0019 0.0019
Echinococcus granulosus microtubule associated protein 2 0.1519 0.6011 0.6011
Echinococcus granulosus cathepsin L cysteine proteinase 0.0863 0.3385 0.3385
Trypanosoma cruzi cysteine proteinase, putative 0.0479 0.1848 0.1848
Echinococcus granulosus caspase 2 0.0158 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0107 0.0359 0.0359
Echinococcus multilocularis hypothetical protein 0.0751 0.2939 0.2939
Loa Loa (eye worm) hypothetical protein 0.003 0.0049 0.0049
Echinococcus granulosus gamma secretase subunit aph 1 0.0252 0.094 0.094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0208 0.028
Echinococcus granulosus cathepsin l1 0.0863 0.3385 0.3385
Schistosoma mansoni inhibitor of apoptosis protein 0.019 0.0691 0.0691
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0089 0.0287 0.0287
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0047 0.0118 0.0356
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0075
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0019 0.0019
Echinococcus granulosus cathepsin l cysteine peptidase 0.0863 0.3385 0.3385
Brugia malayi cathepsin L-like cysteine proteinase 0.0217 0.08 0.08
Echinococcus multilocularis axis inhibition protein axin 0.0042 0.0099 0.0099
Plasmodium vivax vivapain-3 0.0479 0.1848 0.5459
Echinococcus multilocularis peroxidasin 0.0065 0.0189 0.0189
Schistosoma mansoni calmodulin 0.0121 0.0415 0.0415
Leishmania major kinesin, putative 0.0531 0.2057 0.2775
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0262 0.0978 0.0978
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0966 0.38 0.5126
Loa Loa (eye worm) hypothetical protein 0.014 0.0492 0.0492
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0019 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0423 0.1251
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0863 0.3385 0.9287
Onchocerca volvulus 0.0754 0.2951 0.3981
Onchocerca volvulus 0.003 0.0049 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.1318 0.1318
Trypanosoma brucei prolyl oligopeptidase, putative 0.0844 0.3311 0.4467
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0075 0.0125
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0018 0 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0307 0.0307
Echinococcus granulosus axis inhibition protein axin 0.0042 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.022 0.0812 0.2228
Entamoeba histolytica cysteine protease, putative 0.0217 0.08 0.2362
Echinococcus granulosus calumenin 0.0123 0.0423 0.0423
Trypanosoma cruzi centrin, putative 0.0125 0.0429 0.0429
Brugia malayi Pre-SET motif family protein 0.0096 0.0313 0.0313
Plasmodium falciparum proteasome subunit beta type-4 0.0018 0 0.0001
Plasmodium falciparum serine repeat antigen 6 0.0217 0.08 0.2362
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0107 0.0359 0.0359
Toxoplasma gondii cathepsin CPL 0.0863 0.3385 0.4567
Schistosoma mansoni survival motor neuron protein 0.0052 0.014 0.014
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0075 0.0207
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.0005 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0065 0.0189 0.0189
Brugia malayi Kringle domain containing protein 0.0046 0.0115 0.0115
Toxoplasma gondii PAN/Apple domain-containing protein 0.003 0.0049 0.0067
Schistosoma mansoni regulator of G protein signaling 0.0042 0.0099 0.0099
Leishmania major cathepsin L-like protease 0.0863 0.3385 0.4567
Echinococcus granulosus tumor protein p63 0.0372 0.1419 0.1419
Brugia malayi CXXC zinc finger family protein 0.0031 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.019 0.0691 0.0691
Leishmania major cathepsin L-like protease 0.0966 0.38 0.5126
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0075 0.0227
Giardia lamblia Cathepsin L precursor 0.0217 0.08 0.2193
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0019 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0019 0.0019
Entamoeba histolytica cysteine protease, putative 0.0217 0.08 0.2362
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0217 0.08 0.08
Brugia malayi Pre-SET motif family protein 0.0663 0.2584 0.2584
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.1095
Loa Loa (eye worm) hypothetical protein 0.0121 0.0415 0.0415
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0189 0.0255
Trypanosoma brucei cysteine peptidase, putative 0.022 0.0812 0.1095
Trypanosoma brucei kinesin, putative 0.0531 0.2057 0.2775
Entamoeba histolytica protein kinase, putative 0.0531 0.2057 0.6075
Brugia malayi Trypsin family protein 0.0107 0.0359 0.0359
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.0005 0.0005
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.022 0.0812 0.0812
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0217 0.08 0.2362

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 20 % Tested for edema suppression rate with respect to control value in adjuvant arthritis rat ;Range = 0-20% ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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