Detailed information for compound 74415

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 422.535 | Formula: C26H31FN2O2
  • H donors: 1 H acceptors: 1 LogP: 5.18 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1)COc1ccc2c(c1)C13CCCCC3[C@H](C2)N(CC1)[C@@H](C(=O)N)C
  • InChi: 1S/C26H31FN2O2/c1-17(25(28)30)29-12-11-26-10-3-2-7-22(26)24(29)14-19-8-9-21(15-23(19)26)31-16-18-5-4-6-20(27)13-18/h4-6,8-9,13,15,17,22,24H,2-3,7,10-12,14,16H2,1H3,(H2,28,30)/t17-,22?,24+,26?/m1/s1
  • InChiKey: HAFQUPCULBPLGU-ZOERYWIQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Sodium channel alpha subunits; brain (Types I, II, III) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis calmodulin, putative 0.0225 0.0402 0.1111
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Leishmania major cathepsin L-like protease 0.1611 0.3273 0.7778
Leishmania major calpain protease-like protein 0.0409 0.0782 0.1856
Echinococcus multilocularis chromatin regulatory protein sir2 0.0126 0.0195 0.0193
Brugia malayi carbohydrate phosphorylase 0.012 0.0183 0.0183
Echinococcus multilocularis cathepsin L 0.084 0.1676 0.1675
Loa Loa (eye worm) histone deacetylase 1 0.0089 0.0119 0.0119
Schistosoma mansoni cathepsin S (C01 family) 0.039 0.0742 0.0741
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0041 0.0019 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0071
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0041 0.0019 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0253 0.0459 0.0459
Trypanosoma brucei calpain-like protein, putative 0.14 0.2835 0.6735
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0041 0.0019 0.0042
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.0538 0.1448
Echinococcus granulosus microtubule associated protein 2 0.1592 0.3233 0.3232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0233 0.0231
Brugia malayi beta-lactamase family protein 0.0038 0.0013 0.0013
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0027 0.0026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Echinococcus granulosus expressed protein 0.0871 0.1739 0.1738
Loa Loa (eye worm) hypothetical protein 0.0075 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0043 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0146 0.0144
Onchocerca volvulus Peroxidasin homolog 0.0325 0.0608 0.1273
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0145 0.0236 0.0234
Echinococcus multilocularis proteasome subunit beta type 6 0.0041 0.0019 0.0018
Brugia malayi EF hand family protein 0.0222 0.0394 0.0394
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0222 0.0394 0.0393
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0041 0.0019 0.0018
Trypanosoma brucei centrin-3 0.0229 0.0409 0.0969
Echinococcus multilocularis geminin 0.0172 0.0292 0.029
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Plasmodium falciparum plasmepsin X 0.0206 0.0362 0.1182
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Trichomonas vaginalis peptide N-glycanase, putative 0.0291 0.0538 0.1488
Brugia malayi hypothetical protein 0.0043 0.0025 0.0025
Giardia lamblia Cathepsin B precursor 0.1772 0.3605 1
Echinococcus granulosus GPI anchor transamidase 0.0034 0.0005 0.0004
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Loa Loa (eye worm) hypothetical protein 0.0043 0.0025 0.0025
Brugia malayi Cathepsin L-like precursor 0.0451 0.0869 0.0869
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Loa Loa (eye worm) proteasome subunit beta type 3 0.0041 0.0019 0.0019
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.039 0.0742 0.0741
Loa Loa (eye worm) hypothetical protein 0.1454 0.2948 0.2948
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0092 0.0126 0.0124
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.0005
Brugia malayi Histone deacetylase family protein 0.01 0.0141 0.0141
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Echinococcus granulosus Niemann Pick C1 protein 0.0599 0.1175 0.1174
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0041 0.0019 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Echinococcus granulosus Glycosyl transferase family 35 0.012 0.0183 0.0182
Trypanosoma cruzi cysteine peptidase, putative 0.084 0.1676 0.1675
Entamoeba histolytica calpain family cysteine protease, putative 0.0409 0.0782 0.2564
Brugia malayi programmed cell death protein 6 0.0222 0.0394 0.0394
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.039 0.0742 0.2055
Giardia lamblia Cathepsin B precursor 0.039 0.0742 0.2055
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0409 0.0782 0.2166
Entamoeba histolytica cysteine protease, putative 0.039 0.0742 0.2433
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0222 0.0394 0.129
Entamoeba histolytica cysteine proteinase, putative 0.084 0.1676 0.5501
Echinococcus granulosus Proteasome subunit alpha type 7 0.0041 0.0019 0.0018
Brugia malayi regulator of G-protein signaling egl-10 0.0045 0.0027 0.0027
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0126 0.0195 0.0193
Onchocerca volvulus 0.0102 0.0146 0.0305
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.039 0.0742 0.0742
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0041 0.0019 0.0042
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0041 0.0019 0.0058
Plasmodium falciparum cysteine proteinase falcipain 3 0.1502 0.3046 1
Echinococcus multilocularis protein patched 0.0599 0.1175 0.1174
Onchocerca volvulus Peroxidasin homolog 0.0325 0.0608 0.1273
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0049 0.0036 0.0112
Loa Loa (eye worm) hypothetical protein 0.0097 0.0136 0.0136
Echinococcus granulosus cathepsin l1 0.1502 0.3046 0.3045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0222 0.0394 0.0393
Brugia malayi beta-lactamase family protein 0.0038 0.0013 0.0013
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.039 0.0742 0.2433
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0041 0.0019 0.0018
Echinococcus granulosus cpg binding protein 0.0034 0.0005 0.0004
Trypanosoma brucei Aph-1 protein, putative 0.0108 0.0158 0.0372
Loa Loa (eye worm) hypothetical protein 0.0075 0.0089 0.0089
Mycobacterium ulcerans beta-lactamase 0.0038 0.0013 0.004
Onchocerca volvulus 0.0166 0.0279 0.0583
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0041 0.0019 0.0058
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0087 0.0115 0.0113
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.2834
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Schistosoma mansoni hypothetical protein 0.0461 0.0889 0.0888
Echinococcus multilocularis caspase 2 0.0267 0.0488 0.0487
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Toxoplasma gondii proteasome beta subunit 0.0041 0.0019 0.0046
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.039 0.0742 0.2433
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0243 0.0439 0.1039
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0092 0.0126 0.0124
Brugia malayi cathepsin Z-like cysteine proteinase 0.039 0.0742 0.0742
Brugia malayi Protein kinase domain containing protein 0.0049 0.0036 0.0036
Brugia malayi hypothetical protein 0.018 0.0308 0.0308
Brugia malayi calpain family protein 1 0.3738 0.768 0.768
Giardia lamblia Encystation-specific protease 0.039 0.0742 0.2055
Plasmodium falciparum GPI-anchor transamidase, putative 0.0034 0.0005 0.0013
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0409 0.0782 0.0781
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0409 0.0782 0.0781
Schistosoma mansoni histone deacetylase hda2 0.0106 0.0154 0.0153
Brugia malayi Cell death protein 3 precursor 0.0267 0.0488 0.0488
Echinococcus multilocularis histone deacetylase 1 0.0089 0.0119 0.0117
Trypanosoma cruzi metacaspase, putative 0.0087 0.0115 0.0113
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0682 0.1348 0.3737
Entamoeba histolytica hypothetical protein 0.0045 0.0027 0.0085
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Onchocerca volvulus 0.1502 0.3046 0.6372
Entamoeba histolytica cysteine proteinase, putative 0.084 0.1676 0.5501
Giardia lamblia Cysteine protease 0.039 0.0742 0.2055
Brugia malayi Cathepsin L-like precursor 0.1502 0.3046 0.3046
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Echinococcus granulosus calumenin 0.0225 0.0402 0.04
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0018 0.0017
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0027 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0115 0.0314
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.039 0.0742 0.0741
Plasmodium vivax proteasome subunit beta type-4, putative 0.0041 0.0019 0.0058
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0409 0.0782 0.2166
Echinococcus multilocularis Niemann Pick C1 protein 0.0599 0.1175 0.1174
Trypanosoma brucei Calpain-like protein 1.1 0.0409 0.0782 0.1856
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0013 0.0032
Onchocerca volvulus 0.0038 0.0013 0.0028
Trichomonas vaginalis glycogen phosphorylase, putative 0.012 0.0183 0.0504
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0013 0.004
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0041 0.0019 0.0042
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0145 0.0236 0.065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Trypanosoma cruzi oligopeptidase b 0.0838 0.1672 0.167
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0041 0.0019 0.0018
Schistosoma mansoni neuronal calcium sensor 0.0222 0.0394 0.0393
Leishmania major proteasome alpha 3 subunit, putative 0.0041 0.0019 0.0042
Echinococcus granulosus histone deacetylase 6 0.01 0.0141 0.014
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0119 0.0325
Brugia malayi prolyl oligopeptidase family protein 0.2062 0.4208 0.4208
Echinococcus multilocularis cathepsin L cysteine protease 0.1502 0.3046 0.3045
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0041 0.0019 0.0046
Giardia lamblia 20S proteasome alpha subunit 7 0.0041 0.0019 0.0049
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.1454 0.2948 1
Trypanosoma brucei histone deacetylase 1 0.0089 0.0119 0.0278
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Plasmodium vivax GPI-anchor transamidase, putative 0.0034 0.0005 0.0013
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Trypanosoma cruzi metacaspase 5, putative 0.0087 0.0115 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.039 0.0742 0.2055
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0222 0.0394 0.0393
Echinococcus multilocularis beta adrenergic receptor kinase 0.0045 0.0027 0.0026
Schistosoma mansoni caspase-3 (C14 family) 0.0229 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0027
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0041 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Leishmania major protein kinase, putative 0.0222 0.0394 0.0933
Onchocerca volvulus 0.2338 0.478 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0143 0.023 0.0228
Trypanosoma brucei protein I/6 0.0222 0.0394 0.0933
Loa Loa (eye worm) hypothetical protein 0.0102 0.0146 0.0146
Leishmania major centrin, putative 0.0222 0.0394 0.0933
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0097 0.0137 0.0135
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0023 0.0049
Giardia lamblia Cathepsin L precursor 0.039 0.0742 0.2055
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.0119 0.0117
Mycobacterium tuberculosis Conserved protein 0.0038 0.0013 0.0032
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.396 0.8139 0.8139
Schistosoma mansoni hypothetical protein 0.0291 0.0538 0.0536
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.039 0.0742 0.2055
Plasmodium vivax metacaspase 1, putative 0.0087 0.0115 0.0372
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0019 0.0042
Giardia lamblia Hypothetical protein 0.039 0.0742 0.2055
Loa Loa (eye worm) hypothetical protein 0.1051 0.2112 0.2112
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0041 0.0019 0.0046
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.039 0.0742 0.2055
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0041 0.0019 0.0058
Leishmania major cathepsin L-like protease 0.1502 0.3046 0.7237
Toxoplasma gondii ABC1 family protein 0.0038 0.0013 0.0032
Echinococcus multilocularis histone deacetylase 0.01 0.0141 0.014
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0011 0.001
Schistosoma mansoni cathepsin F (C01 family) 0.1051 0.2112 0.2111
Schistosoma mansoni hypothetical protein 0.0222 0.0394 0.0393
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0019 0.0042
Trypanosoma brucei histone deacetylase 3 0.01 0.0141 0.0332
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0126 0.0195 0.0536
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.039 0.0742 0.0741
Entamoeba histolytica cysteine protease, putative 0.1502 0.3046 1
Trichomonas vaginalis calpain, putative 0.0409 0.0782 0.2166
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0041 0.0019 0.0018
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0027 0.0026
Brugia malayi cathepsin F-like cysteine proteinase 0.039 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Loa Loa (eye worm) trypsin family protein 0.0166 0.0279 0.0279
Schistosoma mansoni aldehyde dehydrogenase 0.0143 0.023 0.0228
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0146 0.0144
Echinococcus granulosus dnaJ subfamily B 0.0461 0.0889 0.0888
Loa Loa (eye worm) hypothetical protein 0.1502 0.3046 0.3046
Schistosoma mansoni reticulocalbin 0.0222 0.0394 0.0393
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.039 0.0742 0.2433
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0838 0.1672 0.5669
Entamoeba histolytica grainin, putative 0.0225 0.0402 0.1315
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0093
Trypanosoma brucei calpain, putative 0.0409 0.0782 0.1856
Trypanosoma cruzi metacaspase 5, putative 0.0087 0.0115 0.0113
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0041 0.0019 0.0058
Leishmania major centrin, putative 0.0222 0.0394 0.0933
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0606 0.119 0.119
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0041 0.0019 0.0018
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.0056 0.0054
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0013 0.0033
Echinococcus granulosus geminin 0.0172 0.0292 0.029
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0034 0.0005 0.0004
Brugia malayi Eukaryotic aspartyl protease family protein 0.0043 0.0025 0.0025
Entamoeba histolytica cysteine protease, putative 0.039 0.0742 0.2433
Plasmodium vivax aspartyl proteinase, putative 0.0043 0.0025 0.0076
Plasmodium falciparum histone deacetylase, putative 0.01 0.0141 0.0459
Schistosoma mansoni calmodulin 0.0222 0.0394 0.0393
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.039 0.0742 0.2055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0143 0.023 0.0775
Toxoplasma gondii hypothetical protein 0.0409 0.0782 0.1859
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Loa Loa (eye worm) calpain 5 0.0991 0.1987 0.1987
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0027
Giardia lamblia Cathepsin B precursor 0.039 0.0742 0.2055
Leishmania major proteasome alpha 1 subunit, putative 0.0041 0.0019 0.0042
Loa Loa (eye worm) hypothetical protein 0.039 0.0742 0.0742
Brugia malayi Thioredoxin family protein 0.0291 0.0538 0.0538
Brugia malayi hypothetical protein 0.0043 0.0025 0.0025
Onchocerca volvulus 0.0038 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0087 0.0115 0.0115
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0041 0.0019 0.0042
Echinococcus multilocularis calbindin 32 0.0225 0.0402 0.04
Plasmodium vivax aspartyl protease, putative 0.0206 0.0362 0.1182
Loa Loa (eye worm) hypothetical protein 0.4858 1 1
Schistosoma mansoni hypothetical protein 0.0049 0.0036 0.0034
Leishmania major metacaspase, putative 0.0087 0.0115 0.0269
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0027 0.0026
Echinococcus granulosus cathepsin l1 0.1051 0.2112 0.2111
Echinococcus granulosus histone lysine methyltransferase setb 0.0102 0.0146 0.0144
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0018 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0005 0.0011
Plasmodium vivax vivapain-1 0.084 0.1676 0.5501
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0838 0.1672 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1502 0.3046 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0101 0.0144 0.0143
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.0126 0.0344
Loa Loa (eye worm) hypothetical protein 0.039 0.0742 0.0742
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0145 0.0236 0.0769
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0041 0.0019 0.0042
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0041 0.0019 0.0018
Onchocerca volvulus 0.0166 0.0279 0.0583
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2062 0.4208 0.4207
Brugia malayi Papain family cysteine protease containing protein 0.084 0.1676 0.1676
Trypanosoma cruzi metacaspase, putative 0.0087 0.0115 0.0113
Giardia lamblia Alanyl dipeptidyl peptidase 0.0243 0.0439 0.1213
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0101 0.0144 0.0144
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0045 0.0027 0.0027
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.0019 0.0018
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.084 0.1676 0.3981
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0041 0.0019 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.1611 0.3273 0.3272
Brugia malayi Papain family cysteine protease containing protein 0.039 0.0742 0.0742
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0041 0.0019 0.0018
Brugia malayi CXXC zinc finger family protein 0.0032 0.0002 0.0002
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0126 0.0195 0.0536
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0041 0.0019 0.0018
Echinococcus granulosus histone deacetylase 6 0.01 0.0141 0.014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.6735
Trichomonas vaginalis calpain, putative 0.0409 0.0782 0.2166
Leishmania major proteasome beta 7 subunit, putative 0.0041 0.0019 0.0042
Giardia lamblia Glycogen phosphorylase 0.012 0.0183 0.0504
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Brugia malayi Cytochrome P450 family protein 0.0037 0.0011 0.0011
Loa Loa (eye worm) histone deacetylase 0.01 0.0141 0.0141
Entamoeba histolytica hypothetical protein 0.0045 0.0027 0.0085
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0041 0.0019 0.0058
Schistosoma mansoni aldehyde dehydrogenase 0.0143 0.023 0.0228
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0243 0.0439 0.0437
Schistosoma mansoni cathepsin D (A01 family) 0.0233 0.0418 0.0416
Giardia lamblia Cathepsin B precursor 0.039 0.0742 0.2055
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0041 0.0019 0.0058
Schistosoma mansoni hypothetical protein 0.0166 0.0279 0.0277
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0233 0.0231
Brugia malayi hypothetical protein 0.0325 0.0608 0.0608
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0041 0.0019 0.0035
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0041 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0093
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0045 0.0027 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0222 0.0394 0.0933
Entamoeba histolytica GPI-anchor transamidase, putative 0.0034 0.0005 0.0013
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0041 0.0019 0.0018
Trypanosoma brucei Metacaspase-4 0.0087 0.0115 0.0269
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0043 0.0025 0.0025
Brugia malayi hypothetical protein 0.0045 0.0027 0.0027
Loa Loa (eye worm) proteasome subunit beta type 1 0.0145 0.0236 0.0236
Toxoplasma gondii histone deacetylase HDAC2 0.0089 0.0119 0.0282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.039 0.0742 0.0741
Echinococcus multilocularis tissue type plasminogen activator 0.0049 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.3738 0.768 0.768
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0253 0.0459 0.1237
Entamoeba histolytica cysteine proteinase, putative 0.084 0.1676 0.5501
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0019 0.0042
Loa Loa (eye worm) RGS-3 protein 0.0045 0.0027 0.0027
Trypanosoma cruzi metacaspase, putative 0.0087 0.0115 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Echinococcus multilocularis proteasome subunit beta type 7 0.0041 0.0019 0.0018
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0041 0.0019 0.0018
Echinococcus granulosus histone deacetylase 8 0.0043 0.0023 0.0022
Plasmodium falciparum centrin-1 0.0222 0.0394 0.129
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0027 0.0026
Leishmania major proteasome beta 3 subunit, putative 0.0041 0.0019 0.0042
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0041 0.0019 0.0018
Plasmodium falciparum serine repeat antigen 3 0.039 0.0742 0.2433
Plasmodium falciparum serine repeat antigen 4 0.039 0.0742 0.2433
Onchocerca volvulus 0.039 0.0742 0.1553
Brugia malayi Pre-SET motif family protein 0.0706 0.1398 0.1398
Onchocerca volvulus 0.1051 0.2112 0.4418
Giardia lamblia Cathepsin L precursor 0.039 0.0742 0.2055
Trypanosoma brucei prolyl oligopeptidase, putative 0.0838 0.1672 0.397
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Echinococcus granulosus proteasome subunit alpha type 2 0.0041 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0075 0.0089 0.0089
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0119 0.0325
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0145 0.0236 0.0557
Onchocerca volvulus 0.0804 0.16 0.3348
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0018 0.0055
Echinococcus granulosus cathepsin b 0.4858 1 1
Leishmania major C-8 sterol isomerase-like protein 0.0361 0.0682 0.1618
Echinococcus granulosus transmembrane protease serine 3 0.0166 0.0279 0.0277
Loa Loa (eye worm) histone deacetylase 7A 0.01 0.0141 0.0141
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0013 0.0013
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0041 0.0019 0.0058
Brugia malayi Histone deacetylase family protein 0.01 0.0141 0.0141
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0886 0.1771 0.177
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.0203 0.0203
Schistosoma mansoni neuronal calcium sensor 0.0222 0.0394 0.0393
Brugia malayi Peroxidasin 0.0325 0.0608 0.0608
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0682 0.1348 0.3737
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0838 0.1672 0.167
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0409 0.0782 0.1859
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4858 1 1
Leishmania major histone deacetylase, putative 0.0089 0.0119 0.0278
Toxoplasma gondii centrin, putative 0.0222 0.0394 0.0937
Leishmania major cathepsin L-like protease 0.1502 0.3046 0.7237
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0341 0.064 0.1522
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0041 0.0019 0.0018
Schistosoma mansoni cathepsin C 0.039 0.0742 0.0741
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0054 0.0054
Leishmania major oligopeptidase b 0.0838 0.1672 0.397
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0041 0.0019 0.0018
Trichomonas vaginalis calcineurin B subunit, putative 0.0225 0.0402 0.1111
Entamoeba histolytica cysteine protease, putative 0.039 0.0742 0.2433
Echinococcus multilocularis endothelin converting enzyme 1 0.0101 0.0144 0.0143
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0253 0.0459 0.0458
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0041 0.0019 0.0018
Leishmania major cathepsin L-like protease 0.1502 0.3046 0.7237
Loa Loa (eye worm) blistered cuticle protein 3 0.0325 0.0608 0.0608
Toxoplasma gondii aspartyl protease ASP3 0.0206 0.0362 0.0859
Trypanosoma brucei metacaspase 0.0087 0.0115 0.0269
Trypanosoma brucei cytochrome P450, putative 0.0037 0.0011 0.0023
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0002 0.0002
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.024 0.0239
Schistosoma mansoni hypothetical protein 0.0058 0.0054 0.0052
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0225 0.0402 0.04
Schistosoma mansoni calpain (C02 family) 0.14 0.2835 0.2834
Onchocerca volvulus 0.1502 0.3046 0.6372
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.039 0.0742 0.0741
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Echinococcus multilocularis glycogen phosphorylase 0.012 0.0183 0.0182
Echinococcus multilocularis Transglutaminase 0.0291 0.0538 0.0536
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0409 0.0782 0.0781
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Mycobacterium ulcerans transglutaminase family protein 0.0291 0.0538 0.182
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0143 0.023 0.0228
Echinococcus multilocularis regulator of G protein signaling 3 0.0045 0.0027 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0027 0.0026
Onchocerca volvulus 0.0058 0.0054 0.0113
Brugia malayi Blistered cuticle protein 3 0.0325 0.0608 0.0608
Echinococcus granulosus enteropeptidase 0.0166 0.0279 0.0277
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Entamoeba histolytica prolyl oligopeptidase family protein 0.0243 0.0439 0.1436
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0119 0.0325
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3738 0.768 0.768
Toxoplasma gondii EFHC1, putative 0.0222 0.0394 0.0937
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0087 0.0115 0.0273
Trichomonas vaginalis myosin light chain 1, putative 0.0222 0.0394 0.1089
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.0203 0.0203
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0092 0.0126 0.0124
Schistosoma mansoni cathepsin s 0.0451 0.0869 0.0867
Echinococcus granulosus histone deacetylase 7 0.01 0.0141 0.014
Plasmodium falciparum histone deacetylase 1 0.0089 0.0119 0.0385
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.2834
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.039 0.0742 0.2055
Mycobacterium leprae probable zinc metalloprotease 0.0101 0.0144 0.0788
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0045 0.0027 0.0026
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1454 0.2948 0.7004
Plasmodium vivax aspartyl protease, putative 0.0043 0.0025 0.0076
Schistosoma mansoni cathepsin B (C01 family) 0.039 0.0742 0.0741
Brugia malayi Proteasome subunit alpha type 1 0.0041 0.0019 0.0019
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0002 0.0004
Echinococcus multilocularis glycogen phosphorylase 0.012 0.0183 0.0182
Mycobacterium ulcerans hypothetical protein 0.0166 0.0279 0.0941
Plasmodium falciparum plasmepsin IX 0.0206 0.0362 0.1182
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0141 0.014
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0322 0.0322
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0092 0.0126 0.0124
Giardia lamblia Transglutaminase/protease, putative 0.0291 0.0538 0.1488
Brugia malayi Cytochrome P450 family protein 0.0061 0.0061 0.0061
Trypanosoma cruzi cruzipain precursor, putative 0.0451 0.0869 0.0867
Loa Loa (eye worm) aspartyl protease 6 0.0043 0.0025 0.0025
Trypanosoma cruzi major cysteine proteinase, putative 0.05 0.097 0.0968
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0041 0.0019 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0115 0.0314
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0089 0.0089
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Giardia lamblia Cysteine protease 0.039 0.0742 0.2055
Giardia lamblia 20S proteasome alpha subunit 2 0.0041 0.0019 0.0049
Trypanosoma brucei Calpain-like protein 1.2 0.0409 0.0782 0.1856
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0041 0.0019 0.0058
Brugia malayi Cathepsin L-like precursor 0.1502 0.3046 0.3046
Trypanosoma cruzi centrin, putative 0.0229 0.0409 0.0408
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0041 0.0019 0.0019
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.1454 0.2948 0.2947
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0045 0.0027 0.0026
Echinococcus multilocularis transmembrane protease serine 3 0.0166 0.0279 0.0277
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0041 0.0019 0.0058
Schistosoma mansoni memapsin-2 (A01 family) 0.0532 0.1037 0.1036
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0119 0.0325
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0036 0.0034
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0018 0.0017
Schistosoma mansoni ap endonuclease 0.004 0.0018 0.0017
Echinococcus granulosus calpain 5 0.14 0.2835 0.2834
Onchocerca volvulus 0.0291 0.0538 0.1125
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0092 0.0126 0.0124
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0034 0.0005 0.0009
Toxoplasma gondii peptidase, T1 family protein 0.0041 0.0019 0.0046
Echinococcus granulosus acylamino acid releasing enzyme 0.0243 0.0439 0.0437
Trichomonas vaginalis esterase, putative 0.0038 0.0013 0.0033
Echinococcus multilocularis caspase 3 0.0142 0.0229 0.0227
Schistosoma mansoni cpg binding protein 0.0034 0.0005 0.0004
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1772 0.3605 0.3604
Loa Loa (eye worm) calpain family protein 1 0.2747 0.5627 0.5627
Echinococcus multilocularis proteasome subunit alpha type 2 0.0041 0.0019 0.0018
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0222 0.0394 0.1089
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.084 0.1676 0.1675
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0041 0.0019 0.0046
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0023 0.0023
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0147 0.024 0.0239
Entamoeba histolytica grainin 2 0.0229 0.0409 0.1339
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0838 0.1672 0.451
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0041 0.0019 0.0058
Leishmania major cytochrome p450-like protein 0.0037 0.0011 0.0023
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0019 0.0049
Schistosoma mansoni calpain C (C02 family) 0.14 0.2835 0.2834
Trypanosoma cruzi cysteine protease, putative 0.084 0.1676 0.1675
Echinococcus granulosus caspase 3 0.0142 0.0229 0.0227
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0041 0.0019 1
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0592 0.1162 0.1161
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0041 0.0019 0.0042
Loa Loa (eye worm) calpain D 0.0409 0.0782 0.0782
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Trypanosoma cruzi I/6 autoantigen, putative 0.0222 0.0394 0.0393
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0409 0.0782 0.2166
Trypanosoma cruzi Aph-1 protein, putative 0.0108 0.0158 0.0156
Trypanosoma brucei cysteine peptidase C (CPC) 0.1772 0.3605 0.8567
Echinococcus granulosus peroxidasin 0.0325 0.0608 0.0607
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0002 0.0002
Onchocerca volvulus 0.0187 0.0322 0.0674
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0092 0.0126 0.0344
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1772 0.3605 0.8567
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0233 0.0231
Trypanosoma brucei kinesin, putative 0.0991 0.1987 0.472
Loa Loa (eye worm) cysteine protease 0.1502 0.3046 0.3046
Brugia malayi Peptidase C13 family protein 0.0147 0.024 0.024
Plasmodium vivax hypothetical protein, conserved 0.0243 0.0439 0.1436
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0041 0.0019 0.0018
Echinococcus multilocularis enteropeptidase 0.0166 0.0279 0.0277
Toxoplasma gondii cathepsin CPC2 0.039 0.0742 0.1764
Giardia lamblia Cathepsin L precursor 0.039 0.0742 0.2055
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.039 0.0742 0.2433
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0069 0.0165
Echinococcus multilocularis cysteine protease 0.1502 0.3046 0.3045
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0115 0.0314
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0041 0.0019 0.0018
Echinococcus granulosus calmodulin 0.0222 0.0394 0.0393
Plasmodium vivax proteasome subunit beta type-3, putative 0.0041 0.0019 0.0058
Brugia malayi Cathepsin L-like cysteine proteinase 0.1051 0.2112 0.2112
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0027 0.0026
Entamoeba histolytica cysteine protease, putative 0.039 0.0742 0.2433
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0599 0.1175 0.1174
Brugia malayi Peptidase family M13 containing protein 0.0101 0.0144 0.0144
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0608 0.0608
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0018 0.0055
Schistosoma mansoni cpg binding protein 0.0032 0.0002 0.0000099302
Trypanosoma brucei Calpain-like protein 2 0.0409 0.0782 0.1856
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.039 0.0742 0.2055
Echinococcus granulosus cathepsin L 0.039 0.0742 0.0741
Brugia malayi cathepsin L-like cysteine proteinase 0.039 0.0742 0.0742
Leishmania major hypothetical protein, conserved 0.0409 0.0782 0.1856
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0225 0.0402 0.04
Plasmodium vivax vivapain-2 0.1502 0.3046 1
Plasmodium falciparum serine repeat antigen 5 0.039 0.0742 0.2433
Trypanosoma cruzi calmodulin, putative 0.0222 0.0394 0.0393
Schistosoma mansoni cathepsin D (A01 family) 0.0233 0.0418 0.0416
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0126 0.0195 0.0193
Trypanosoma cruzi Aph-1 protein, putative 0.0108 0.0158 0.0156
Echinococcus granulosus proteasome subunit beta type 7 0.0041 0.0019 0.0018
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0608 0.0608
Echinococcus multilocularis prolyl endopeptidase 0.2062 0.4208 0.4207
Trypanosoma cruzi cysteine peptidase, putative 0.1611 0.3273 0.3272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.039 0.0742 0.2055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0019 0.0049
Echinococcus multilocularis regulator of G protein signaling 7 0.0045 0.0027 0.0026
Mycobacterium ulcerans lipase LipD 0.0038 0.0013 0.004
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.6735
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.0119 0.0117
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0409 0.0782 0.0781
Plasmodium falciparum proteasome subunit beta type-4 0.0041 0.0019 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0071
Schistosoma mansoni histone deacetylase 0.0089 0.0119 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.039 0.0742 0.2055
Entamoeba histolytica papain family cysteine protease domain containing protein 0.039 0.0742 0.2433
Brugia malayi proteasome subunit alpha type 3 0.0041 0.0019 0.0019
Giardia lamblia Proteasome subunit beta type 3 0.0041 0.0019 0.0049
Loa Loa (eye worm) hypothetical protein 0.0057 0.0053 0.0053
Brugia malayi proteasome subunit alpha type 6 0.0041 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.1051 0.2112 0.2112
Loa Loa (eye worm) hypothetical protein 0.2747 0.5627 0.5627
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0013 0.0033
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.396 0.8139 0.8139
Trypanosoma cruzi kinesin, putative 0.0991 0.1987 0.1986
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0041 0.0019 0.0018
Echinococcus multilocularis calpain 0.14 0.2835 0.2834
Echinococcus multilocularis programmed cell death protein 0.0229 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0222 0.0394 0.0394
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0013 0.004
Mycobacterium ulcerans zinc metalloprotease 0.0101 0.0144 0.0484
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0018 0.0055
Echinococcus multilocularis glycoprotein Antigen 5 0.0166 0.0279 0.0277
Toxoplasma gondii aspartyl protease 0.0043 0.0025 0.0059
Entamoeba histolytica prolyl oligopeptidase family protein 0.0243 0.0439 0.1436
Onchocerca volvulus 0.0166 0.0279 0.0583
Schistosoma mansoni hypothetical protein 0.0172 0.0292 0.029
Leishmania major proteasome beta 2 subunit, putative 0.0041 0.0019 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0071
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Trypanosoma cruzi centrin, putative 0.0229 0.0409 0.0408
Plasmodium vivax calpain, putative 0.14 0.2835 0.9306
Giardia lamblia Cathepsin B precursor 0.039 0.0742 0.2055
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0027 0.0026
Entamoeba histolytica calmodulin, putative 0.0222 0.0394 0.129
Plasmodium falciparum serine repeat antigen 7 0.039 0.0742 0.2433
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.039 0.0742 0.2433
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0145 0.0236 0.0234
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0145 0.0236 0.0769
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0093
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.0119 0.0325
Loa Loa (eye worm) hypothetical protein 0.039 0.0742 0.0742
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0027 0.0026
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0027
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0011 0.0011
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0041 0.0019 0.0046
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1502 0.3046 1
Onchocerca volvulus Glycogen phosphorylase homolog 0.012 0.0183 0.0383
Entamoeba histolytica cysteine protease, putative 0.039 0.0742 0.2433
Brugia malayi cathepsin Z-like cysteine proteinase 0.039 0.0742 0.0742
Giardia lamblia Cathepsin L precursor 0.039 0.0742 0.2055
Leishmania major proteasome alpha 1 subunit, putative 0.0041 0.0019 0.0042
Schistosoma mansoni caspase-7 (C14 family) 0.0229 0.0409 0.0408
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0341 0.064 0.1519
Plasmodium vivax proteasome subunit beta type-7, putative 0.0041 0.0019 0.0058
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0409 0.0782 0.1856
Entamoeba histolytica calcium-binding protein, putative 0.0222 0.0394 0.129
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0018 0.0017
Echinococcus granulosus glycogen phosphorylase 0.012 0.0183 0.0182
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0187 0.0322 0.0322
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0087 0.0115 0.0273
Plasmodium falciparum plasmepsin V 0.0043 0.0025 0.0076
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.0538 0.1448
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0222 0.0394 0.0933
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0092 0.0126 0.0295
Loa Loa (eye worm) hypothetical protein 0.0184 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Toxoplasma gondii calcium-dependent protein kinase 0.0225 0.0402 0.0955
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Trypanosoma brucei proteasome alpha 7 subunit 0.0041 0.0019 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.1454 0.2948 0.2947
Schistosoma mansoni calmodulin 0.0222 0.0394 0.0393
Mycobacterium ulcerans hypothetical protein 0.0291 0.0538 0.182
Loa Loa (eye worm) hypothetical protein 0.018 0.0308 0.0308
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Trypanosoma brucei hypothetical protein 0.0409 0.0782 0.1856
Entamoeba histolytica cysteine proteinase, putative 0.1051 0.2112 0.6932
Schistosoma mansoni survival motor neuron protein 0.0058 0.0054 0.0052
Onchocerca volvulus 0.0222 0.0394 0.0825
Onchocerca volvulus 0.0049 0.0036 0.0075
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0222 0.0394 0.0393
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0027 0.0026
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0041 0.0019 0.0042
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.396 0.8139 0.8139
Echinococcus multilocularis hypothetical protein 0.14 0.2835 0.2834
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.039 0.0742 0.2055
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0187 0.0322 0.0321
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.1454 0.2948 0.2947
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0101 0.0144 0.0144
Giardia lamblia Cathepsin B precursor 0.039 0.0742 0.2055
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0013 0.0012
Plasmodium falciparum serine repeat antigen 8 0.039 0.0742 0.2433
Echinococcus multilocularis histone deacetylase 7 0.01 0.0141 0.014
Loa Loa (eye worm) EF hand family protein 0.0222 0.0394 0.0394
Loa Loa (eye worm) histone deacetylase 3 0.0089 0.0119 0.0119
Schistosoma mansoni chromatin regulatory protein sir2 0.0126 0.0195 0.0193
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0341 0.064 0.0639
Entamoeba histolytica cysteine proteinase, putative 0.1502 0.3046 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0041 0.0019 0.0058
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0409 0.0782 0.0781
Brugia malayi proteasome subunit beta type 2 0.0092 0.0126 0.0126
Entamoeba histolytica hypothetical protein, conserved 0.0243 0.0439 0.1436
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Onchocerca volvulus Notchless protein homolog 0.0041 0.0019 0.004
Plasmodium falciparum plasmepsin IV 0.0043 0.0025 0.0076
Echinococcus granulosus cathepsin L cysteine protease 0.084 0.1676 0.1675
Giardia lamblia Cathepsin B precursor 0.1772 0.3605 1
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0243 0.0439 0.1213
Trypanosoma brucei C-8 sterol isomerase, putative 0.0361 0.0682 0.1618
Toxoplasma gondii cathepsin B 0.1772 0.3605 0.8568
Entamoeba histolytica papain family cysteine protease domain containing protein 0.039 0.0742 0.2433
Trypanosoma brucei centrin, putative 0.0222 0.0394 0.0933
Mycobacterium tuberculosis Hypothetical protein 0.0291 0.0538 0.1448
Leishmania major programmed cell death 6 protein-like protein 0.0222 0.0394 0.0933
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0341 0.064 0.0639
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1502 0.3046 0.3046
Onchocerca volvulus 0.0166 0.0279 0.0583
Trypanosoma cruzi cysteine proteinase, putative 0.084 0.1676 0.1675
Onchocerca volvulus 0.0043 0.0025 0.0052
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4858 1 1
Brugia malayi A-kinase anchor protein 10, precursor 0.0045 0.0027 0.0027
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0061 0.0061
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.0011 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0451 0.0869 0.0867
Entamoeba histolytica glycogen phosphorylase, putative 0.012 0.0183 0.0596
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0166 0.0279 0.0277
Leishmania major proteasome alpha 2 subunit, putative 0.0041 0.0019 0.0042
Plasmodium vivax plasmepsin V, putative 0.0043 0.0025 0.0076
Loa Loa (eye worm) hypothetical protein 0.2338 0.478 0.478
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Toxoplasma gondii exonuclease III APE 0.004 0.0018 0.0044
Echinococcus multilocularis apoptotic protease activating factor 1 0.018 0.0308 0.0306
Echinococcus multilocularis peroxidasin 0.0325 0.0608 0.0607
Trypanosoma cruzi oligopeptidase b 0.0838 0.1672 0.167
Brugia malayi histone deacetylase 1 (HD1) 0.0089 0.0119 0.0119
Onchocerca volvulus Prolyl endopeptidase homolog 0.2062 0.4208 0.8804
Giardia lamblia Dipeptidyl-peptidase I precursor 0.039 0.0742 0.2055
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0451 0.0869 0.0869
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0034 0.0005 0.0004
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0233 0.0233
Mycobacterium tuberculosis Conserved protein 0.0291 0.0538 0.1448
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0187 0.0322 0.0321
Echinococcus granulosus gamma secretase subunit aph 1 0.0276 0.0508 0.0506
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0592 0.1162 0.1161
Trichomonas vaginalis calcium binding protein, putative 0.0229 0.0409 0.1131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Echinococcus granulosus programmed cell death protein 0.0229 0.0409 0.0408
Echinococcus granulosus sterol regulatory element binding protein 0.0599 0.1175 0.1174
Loa Loa (eye worm) peptidase C13 family protein 0.0147 0.024 0.024
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0002 0.0002
Echinococcus granulosus Mastin 0.0166 0.0279 0.0277
Onchocerca volvulus 0.0043 0.0025 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0599 0.1175 0.3256
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0041 0.0019 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0092 0.0126 0.0298
Leishmania major proteasome beta 2 subunit, putative 0.0092 0.0126 0.0295
Loa Loa (eye worm) programmed cell death protein 6 0.0225 0.0402 0.0402
Echinococcus multilocularis dnaJ subfamily B 0.0461 0.0889 0.0888
Trichomonas vaginalis calmodulin, putative 0.0229 0.0409 0.1131
Giardia lamblia 20S proteasome alpha subunit 3 0.0041 0.0019 0.0049
Trypanosoma cruzi cysteine proteinase, putative 0.084 0.1676 0.1675
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0043 0.0025 0.0059
Trypanosoma brucei caltractin, putative 0.0229 0.0409 0.0969
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0051 0.004 0.0039
Plasmodium vivax proteasome subunit beta type-6, putative 0.0041 0.0019 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0243 0.0439 0.0437
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0409 0.0782 0.0781
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Schistosoma mansoni centrin-related 0.0222 0.0394 0.0393
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0045 0.0027 0.0027
Echinococcus granulosus centrin 2 0.0222 0.0394 0.0393
Echinococcus multilocularis acylamino acid releasing enzyme 0.0243 0.0439 0.0437
Loa Loa (eye worm) hypothetical protein 0.0222 0.0394 0.0394
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0041 0.0019 0.0018
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0052 0.0042 0.0137
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0243 0.0439 0.0437
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0013 0.0028
Entamoeba histolytica protein kinase, putative 0.0991 0.1987 0.6522
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0063 0.0065 0.0065
Echinococcus granulosus EF hand domain containing family member A2 0.0225 0.0402 0.04
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0027
Brugia malayi Papain family cysteine protease containing protein 0.1502 0.3046 0.3046
Trypanosoma cruzi calpain cysteine peptidase, putative 0.14 0.2835 0.2834
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0838 0.1672 0.397
Schistosoma mansoni caspase-7 (C14 family) 0.0267 0.0488 0.0487
Brugia malayi hypothetical protein 0.0282 0.052 0.052
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0041 0.0019 0.0058
Plasmodium vivax plasmepsin IV, putative 0.0043 0.0025 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0027 0.0026
Mycobacterium ulcerans putative transglutaminase-like protein 0.0291 0.0538 0.182
Schistosoma mansoni ap endonuclease 0.004 0.0018 0.0017
Trypanosoma brucei I/6 autoantigen 0.0222 0.0394 0.0933
Giardia lamblia 20S proteasome alpha subunit 5 0.0041 0.0019 0.0049
Brugia malayi prolyl oligopeptidase family protein 0.0243 0.0439 0.0439
Onchocerca volvulus 0.018 0.0308 0.0644
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0126 0.0195 0.0635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0416 0.0796 0.0795
Brugia malayi Trypsin family protein 0.0166 0.0279 0.0279
Echinococcus multilocularis neuronal calcium sensor 0.0222 0.0394 0.0393
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0013 0.0012
Entamoeba histolytica histone deacetylase, putative 0.0089 0.0119 0.0385
Plasmodium falciparum plasmepsin III 0.0043 0.0025 0.0076
Echinococcus multilocularis expressed protein 0.0871 0.1739 0.1738
Giardia lamblia Cathepsin L precursor 0.039 0.0742 0.2055
Loa Loa (eye worm) prolyl oligopeptidase 0.0243 0.0439 0.0439
Schistosoma mansoni peroxidasin 0.0325 0.0608 0.0607
Plasmodium falciparum proteasome subunit beta type-5 0.0253 0.0459 0.1504
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Toxoplasma gondii proteasome subunit alpha type, putative 0.0041 0.0019 0.0046
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.084 0.1676 0.1675
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0361 0.0682 0.0681
Schistosoma mansoni neuronal calcium sensor 0.0222 0.0394 0.0393
Echinococcus multilocularis EF hand domain containing family member A2 0.0222 0.0394 0.0393
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0092 0.0126 0.0407
Mycobacterium ulcerans hypothetical protein 0.0291 0.0538 0.182
Plasmodium vivax vivapain-2 0.1502 0.3046 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0156 0.0156
Brugia malayi NAD-dependent deacetylase SIRT1 0.0139 0.0223 0.0223
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0019 0.0042
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0041 0.0019 0.0058
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0119 0.0325
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0276 0.0508 0.0508
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.2834
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0145 0.0236 0.056
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0018 0.5
Onchocerca volvulus 0.1502 0.3046 0.6372
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0409 0.0782 0.2166
Toxoplasma gondii proteasome subunit alpha1, putative 0.0041 0.0019 0.0046
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0361 0.0682 0.0682
Plasmodium vivax serine-repeat antigen (SERA), putative 0.039 0.0742 0.2433
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0141 0.014
Brugia malayi Proteasome A-type and B-type family protein 0.0041 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Leishmania major calmodulin-like protein 0.0222 0.0394 0.0933
Echinococcus multilocularis microtubule associated protein 2 0.1592 0.3233 0.3232
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0341 0.064 0.0639
Loa Loa (eye worm) glycogen phosphorylase 0.012 0.0183 0.0183
Plasmodium falciparum calpain 0.0409 0.0782 0.2564
Brugia malayi Cathepsin L-like precursor 0.1502 0.3046 0.3046
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0243 0.0439 0.1213
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Echinococcus multilocularis gamma secretase subunit aph 1 0.0276 0.0508 0.0506
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0019 0.0042
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0041 0.0019 0.0018
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0043 0.0025 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.039 0.0742 0.2055
Plasmodium vivax aspartyl proteinase, putative 0.0043 0.0025 0.0076
Echinococcus multilocularis histone deacetylase 6 0.0106 0.0154 0.0153
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Brugia malayi Proteasome A-type and B-type family protein 0.0041 0.0019 0.0019
Trypanosoma brucei Component of motile flagella 41 0.0222 0.0394 0.0933
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0013 0.0039
Toxoplasma gondii histone deacetylase HDAC3 0.0089 0.0119 0.0282
Leishmania major cathepsin L-like protease 0.1611 0.3273 0.7778
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0101 0.0144 0.0385
Trichomonas vaginalis calpain, putative 0.0409 0.0782 0.2166
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2062 0.4208 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.1502 0.3046 0.3045
Loa Loa (eye worm) beta-lactamase 0.0038 0.0013 0.0013
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0018
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0139 0.0223 0.0221
Toxoplasma gondii peptidase c13 family protein 0.0034 0.0005 0.0013
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0222 0.0394 0.0393
Entamoeba histolytica glycogenphosphorylase, putative 0.0052 0.0042 0.0133
Plasmodium falciparum peptidase, putative 0.0243 0.0439 0.1436
Brugia malayi Kringle domain containing protein 0.0049 0.0036 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0233 0.0231
Echinococcus multilocularis cysteine protease 0.1502 0.3046 0.3045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Leishmania major calpain family cysteine protease-like protein 0.0409 0.0782 0.1856
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0409 0.0782 0.0781
Loa Loa (eye worm) animal heme peroxidase 0.0325 0.0608 0.0608
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0041 0.0019 0.0018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.14 0.2835 0.2834
Plasmodium falciparum cysteine repeat modular protein 1 0.0049 0.0036 0.0112
Giardia lamblia Dipeptidyl-peptidase I precursor 0.039 0.0742 0.2055
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4858 1 1
Echinococcus granulosus caspase 0.0229 0.0409 0.0408
Brugia malayi proteasome subunit alpha type 2 0.0041 0.0019 0.0019
Toxoplasma gondii hypothetical protein 0.0243 0.0439 0.1042
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0024 0.0057
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.039 0.0742 0.2433
Trichomonas vaginalis glycogen phosphorylase, putative 0.012 0.0183 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.039 0.0742 0.2055
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0187 0.0322 0.0321
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0013 0.0033
Schistosoma mansoni axis inhibition protein axin 0.0045 0.0027 0.0026
Entamoeba histolytica cysteine proteinase 1, putative 0.084 0.1676 0.5501
Plasmodium vivax serine-repeat antigen (SERA), putative 0.039 0.0742 0.2433
Echinococcus granulosus glycogen phosphorylase 0.012 0.0183 0.0182
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Plasmodium falciparum serine repeat antigen 6 0.039 0.0742 0.2433
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0438 0.1179
Trypanosoma brucei calpain-like protein, putative 0.14 0.2835 0.6735
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Plasmodium vivax aspartyl protease, putative 0.0206 0.0362 0.1182
Trichomonas vaginalis conserved hypothetical protein 0.0243 0.0439 0.1213
Plasmodium vivax unspecified product 0.084 0.1676 0.5501
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0041 0.0019 0.0042
Echinococcus granulosus calpain 7 C02 family 0.14 0.2835 0.2834
Trichomonas vaginalis calcium binding protein, putative 0.0222 0.0394 0.1089
Echinococcus multilocularis calumenin 0.0225 0.0402 0.04
Schistosoma mansoni cathepsin F (C01 family) 0.1502 0.3046 0.3045
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0041 0.0019 0.0018
Brugia malayi cathepsin L-like precursor 0.1051 0.2112 0.2112
Leishmania major phospholipase c-like protein 0.0222 0.0394 0.0933
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0023 0.0055
Echinococcus granulosus axis inhibition protein axin 0.0045 0.0027 0.0026
Brugia malayi calpain family protein 1 0.3738 0.768 0.768
Onchocerca volvulus 0.1502 0.3046 0.6372
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0041 0.0019 0.0018
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0042 0.0133
Plasmodium vivax hypothetical protein, conserved 0.0225 0.0402 0.1315
Mycobacterium ulcerans aldehyde dehydrogenase 0.0143 0.023 0.0775
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0041 0.0019 0.0018
Leishmania major calmodulin-like protein 0.0222 0.0394 0.0933
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0041 0.0019 0.0058
Trypanosoma brucei histone deacetylase, putative 0.01 0.0141 0.0332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.14 0.2835 0.2834
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0011 0.001
Echinococcus multilocularis caspase 0.0229 0.0409 0.0408
Onchocerca volvulus 0.005 0.0038 0.008
Brugia malayi Proteasome subunit alpha type 7-1 0.0041 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.039 0.0742 0.0742
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0018 0.0047
Giardia lamblia Cysteine protease 0.039 0.0742 0.2055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0409 0.0782 0.0781
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0013 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0115 0.0314
Loa Loa (eye worm) calpain 0.14 0.2835 0.2835
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0043 0.0025 0.0023
Brugia malayi gamma-secretase subunit aph-1 0.0276 0.0508 0.0508
Echinococcus granulosus histone deacetylase 1 0.0089 0.0119 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Echinococcus multilocularis calpain 5 0.14 0.2835 0.2834
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0102 0.0146 0.0346
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0041 0.0019 0.0058
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0145 0.0236 0.0234
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0027 0.0026
Brugia malayi Angiotensin-converting enzyme family protein 0.0606 0.119 0.119
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0608 0.0608
Giardia lamblia 20S proteasome alpha subunit 1 0.0041 0.0019 0.0049
Leishmania major hypothetical protein, conserved 0.0038 0.0013 0.0028
Echinococcus granulosus caspase 8 0.0087 0.0115 0.0113
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0041 0.0019 0.0018
Plasmodium falciparum plasmepsin II 0.0043 0.0025 0.0076
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0041 0.0019 0.0058
Trypanosoma brucei cysteine peptidase, putative 0.0409 0.0782 0.1856
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Brugia malayi aspartic protease BmAsp-1, identical 0.0043 0.0025 0.0025
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0041 0.0019 0.0018
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0041 0.0019 0.0018
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0018 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1772 0.3605 1
Loa Loa (eye worm) hypothetical protein 0.0599 0.1175 0.1175
Brugia malayi Pre-SET motif family protein 0.0102 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0187 0.0322 0.0321
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0013 0.0032
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.039 0.0742 0.2433
Leishmania major silent information regulator 2, putative 0.0126 0.0195 0.046
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0043 0.0025 0.0023
Leishmania major calcineurin B subunit, putative 0.0222 0.0394 0.0933
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0005 0.0011
Entamoeba histolytica calmodulin, putative 0.0222 0.0394 0.129
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0041 0.0019 0.0058
Brugia malayi prolyl oligopeptidase family protein 0.0341 0.064 0.064
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0141 0.014
Brugia malayi proteasome subunit beta type 1 0.0145 0.0236 0.0236
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0045 0.0027 0.0071
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0223 0.0613
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0146 0.0144
Onchocerca volvulus 0.0325 0.0608 0.1273
Entamoeba histolytica glycogen phosphorylase, putative 0.012 0.0183 0.0596
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0041 0.0019 0.0058
Echinococcus granulosus EF hand domain containing family member A2 0.0222 0.0394 0.0393
Giardia lamblia Hypothetical protein 0.039 0.0742 0.2055
Toxoplasma gondii cathepsin CPL 0.1502 0.3046 0.7238
Brugia malayi Histone deacetylase 1 0.0089 0.0119 0.0119
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0013 0.0032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Plasmodium vivax proteasome subunit beta type-1, putative 0.0145 0.0236 0.0769
Entamoeba histolytica prolyl oligopeptidase family protein 0.0243 0.0439 0.1436
Leishmania major histone deacetylase, putative 0.0089 0.0119 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.039 0.0742 0.2055
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1819 0.3704 1
Trypanosoma cruzi calmodulin, putative 0.0222 0.0394 0.0393
Trypanosoma brucei calpain, putative 0.0409 0.0782 0.1856
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1502 0.3046 0.3046
Onchocerca volvulus 0.0032 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0222 0.0394 0.1089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.14 0.2835 0.2834
Schistosoma mansoni glycogen phosphorylase 0.0052 0.0042 0.004
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0126 0.0195 0.0193
Schistosoma mansoni calpain-2 (C02 family) 0.0409 0.0782 0.0781
Brugia malayi Cytochrome P450 family protein 0.0037 0.0011 0.0011
Trypanosoma brucei metacaspase 5, putative 0.0087 0.0115 0.0269
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0608 0.0608
Entamoeba histolytica calcium binding family protein 0.0222 0.0394 0.129
Loa Loa (eye worm) hypothetical protein 0.0409 0.0782 0.0782
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0041 0.0019 0.0058
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0027 0.0026
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.0119 0.0325
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.2834
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0041 0.0019 0.0058
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0092 0.0126 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0115 0.0314
Entamoeba histolytica hypothetical protein, conserved 0.0225 0.0402 0.1315
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0233 0.0233
Schistosoma mansoni glycogen phosphorylase 0.012 0.0183 0.0182
Trichomonas vaginalis calcineurin B subunit, putative 0.0222 0.0394 0.1089
Echinococcus granulosus calpain 0.14 0.2835 0.2834
Echinococcus granulosus proteasome subunit beta type 6 0.0041 0.0019 0.0018
Mycobacterium tuberculosis Conserved protein 0.0038 0.0013 0.0032
Brugia malayi Proteasome A-type and B-type family protein 0.0041 0.0019 0.0019
Onchocerca volvulus Cathepsin L homolog 0.1502 0.3046 0.6372
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Schistosoma mansoni cathepsin F (C01 family) 0.1502 0.3046 0.3045
Giardia lamblia Cathepsin L-like protease 0.039 0.0742 0.2055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0018 0.004
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0027 0.0027
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0253 0.0459 0.1504
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0071
Echinococcus granulosus calcium uptake protein 1 0.0225 0.0402 0.04
Plasmodium vivax unspecified product 0.0451 0.0869 0.2848
Loa Loa (eye worm) hypothetical protein 0.0187 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0042
Brugia malayi calcium-binding protein 0.0222 0.0394 0.0394
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0087 0.0115 0.0273
Brugia malayi Trypsin-like protease protein 5 0.0166 0.0279 0.0279
Brugia malayi Cathepsin L-like precursor 0.1502 0.3046 0.3046
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0041 0.0019 0.0058
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Plasmodium falciparum metacaspase 1 0.0087 0.0115 0.0372
Brugia malayi histone deacetylase 3 (HD3) 0.0089 0.0119 0.0119
Onchocerca volvulus Chorion peroxidase homolog 0.0325 0.0608 0.1273
Brugia malayi cathepsin L precursor 0.039 0.0742 0.0742
Schistosoma mansoni hypothetical protein 0.0172 0.0292 0.029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0233 0.0231
Echinococcus granulosus chromatin regulatory protein sir2 0.0126 0.0195 0.0193
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Echinococcus granulosus prolyl endopeptidase 0.2062 0.4208 0.4207
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0041 0.0019 0.0018
Brugia malayi calpain 5 0.0991 0.1987 0.1987
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.039 0.0742 0.2055
Echinococcus multilocularis calcium uptake protein 1 0.0225 0.0402 0.04
Schistosoma mansoni calpain-7 (C02 family) 0.1403 0.2841 0.284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Loa Loa (eye worm) papain family cysteine protease containing protein 0.039 0.0742 0.0742
Brugia malayi PXA domain containing protein 0.0045 0.0027 0.0027
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0041 0.0019 0.0058
Echinococcus multilocularis cathepsin b 0.4858 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0027 0.0026
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0041 0.0019 0.0046
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Plasmodium vivax serine-repeat antigen (SERA) 0.039 0.0742 0.2433
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Trypanosoma brucei prolyl endopeptidase 0.2062 0.4208 1
Trypanosoma brucei metacaspase MCA2 0.0087 0.0115 0.0269
Echinococcus granulosus proteasome prosome macropain 0.0253 0.0459 0.0458
Onchocerca volvulus Cathepsin L homolog 0.1502 0.3046 0.6372
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0001 0.0001
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0041 0.0019 0.0018
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0253 0.0459 0.0458
Trypanosoma brucei calmodulin, putative 0.0225 0.0402 0.0951
Trypanosoma brucei mitochondrial calcium uptake 1 0.0222 0.0394 0.0933
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0018 0.0018
Onchocerca volvulus Cathepsin F homolog 0.1502 0.3046 0.6372
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.039 0.0742 0.2433
Toxoplasma gondii troponin c, isotype gamma, putative 0.0222 0.0394 0.0937
Brugia malayi beta-lactamase 0.0038 0.0013 0.0013
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0023 0.0022
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0253 0.0459 0.0458
Mycobacterium ulcerans proteasome PrcB 0.0253 0.0459 0.1554
Mycobacterium leprae Conserved hypothetical protein 0.0291 0.0538 0.3163
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.14 0.2835 0.2834
Schistosoma mansoni histone deacetylase 0.0089 0.0119 0.0117
Trypanosoma brucei histone deacetylase 2 0.0043 0.0023 0.0052
Trypanosoma brucei calmodulin, putative 0.0222 0.0394 0.0933
Echinococcus multilocularis programmed cell death protein 0.0229 0.0409 0.0408
Loa Loa (eye worm) hypothetical protein 0.0139 0.0223 0.0223
Schistosoma mansoni hypothetical protein 0.0113 0.0169 0.0168
Brugia malayi transcriptional regulator, Sir2 family protein 0.0126 0.0195 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2062 0.4208 0.4207
Schistosoma mansoni gamma-secretase subunit aph-1 0.0276 0.0508 0.0506
Echinococcus multilocularis cathepsin L cysteine protease 0.1502 0.3046 0.3045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.039 0.0742 0.2055
Echinococcus multilocularis calpain A 0.3963 0.8147 0.8147
Entamoeba histolytica calpain large subunit domain III containing protein 0.0991 0.1987 0.6522
Echinococcus granulosus glycoprotein Antigen 5 0.0166 0.0279 0.0277
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0041 0.0019 0.0018
Brugia malayi 20S proteasome alpha5 subunit 0.0041 0.0019 0.0019
Toxoplasma gondii aldehyde dehydrogenase 0.0143 0.023 0.0546
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0243 0.0439 0.0439
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0222 0.0394 0.0393
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.039 0.0742 0.2433
Giardia lamblia Hypothetical protein 0.0126 0.0195 0.0536
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0229 0.0409 0.0408
Entamoeba histolytica hypothetical protein 0.0045 0.0027 0.0085
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0027 0.0026
Plasmodium vivax histone deacetylase 1, putative 0.0089 0.0119 0.0385
Giardia lamblia Proteasome subunit beta type 1 0.0145 0.0236 0.065
Trichomonas vaginalis calmodulin, putative 0.0222 0.0394 0.1089
Loa Loa (eye worm) hypothetical protein 0.0187 0.0322 0.0322
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0102 0.0146 0.0144
Trichomonas vaginalis calcium binding protein, putative 0.0222 0.0394 0.1089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.039 0.0742 0.2055
Brugia malayi calpain 5 0.0409 0.0782 0.0782
Entamoeba histolytica cysteine protease, putative 0.039 0.0742 0.2433
Echinococcus granulosus survival motor neuron protein 1 0.0282 0.052 0.0518
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0052 0.0042 0.0109
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0045 0.0027 0.0027
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0018 0.0045
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0041 0.0019 0.0058
Echinococcus granulosus Proteasome subunit alpha beta 0.0041 0.0019 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Echinococcus granulosus calpain A 0.3963 0.8147 0.8147
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.039 0.0742 0.2055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0041 0.0019 0.0018
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0145 0.0236 0.0234
Loa Loa (eye worm) sirtuin 4 0.0032 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.2062 0.4208 0.4208
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0222 0.0394 0.0933
Plasmodium falciparum plasmepsin VII 0.0043 0.0025 0.0076
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0051 0.004 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0146 0.0144
Echinococcus multilocularis axis inhibition protein axin 0.0045 0.0027 0.0026
Trypanosoma brucei calpain-like protein, putative 0.14 0.2835 0.6735
Echinococcus multilocularis cathepsin b 0.4858 1 1
Plasmodium falciparum serine repeat antigen 2 0.039 0.0742 0.2433
Brugia malayi hypothetical protein 0.0097 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0001
Trypanosoma cruzi prolyl endopeptidase 0.2062 0.4208 0.4207
Giardia lamblia GPI-anchor transamidase, putative 0.0034 0.0005 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Loa Loa (eye worm) hypothetical protein 0.0101 0.0144 0.0144
Brugia malayi PXA domain containing protein 0.0045 0.0027 0.0027
Echinococcus granulosus histone deacetylase 0.01 0.0141 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.039 0.0742 0.2055
Schistosoma mansoni peroxidasin 0.0325 0.0608 0.0607
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Brugia malayi Cathepsin L-like precursor 0.1051 0.2112 0.2112
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0034 0.0005 0.0009
Brugia malayi regulator of G-protein signaling rgs-7 0.0045 0.0027 0.0027
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0013 0.0033
Brugia malayi Papain family cysteine protease containing protein 0.084 0.1676 0.1676
Loa Loa (eye worm) TK/ROR protein kinase 0.0049 0.0036 0.0036
Loa Loa (eye worm) fibroinase 0.1502 0.3046 0.3046
Onchocerca volvulus 0.0166 0.0279 0.0583
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0139 0.0223 0.0613
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.14 0.2835 0.2834
Leishmania major hypothetical protein, conserved 0.0225 0.0402 0.0951
Schistosoma mansoni neprilysin-2 (M13 family) 0.0051 0.004 0.0039
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Plasmodium vivax proteasome subunit beta type-5, putative 0.0253 0.0459 0.1504
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0013 0.0032
Toxoplasma gondii kringle domain-containing protein 0.0049 0.0036 0.0085
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0041 0.0019 0.0042
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0223 0.0613
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0013 0.0012
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0229 0.0409 0.0408
Brugia malayi prolyl oligopeptidase family protein 0.0243 0.0439 0.0439
Plasmodium falciparum plasmepsin I 0.0043 0.0025 0.0076
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0608 0.0608
Plasmodium vivax SET domain protein, putative 0.0102 0.0146 0.0474
Loa Loa (eye worm) hypothetical protein 0.0243 0.0439 0.0439
Brugia malayi hypothetical protein 0.0045 0.0027 0.0027
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0451 0.0869 0.0869
Plasmodium falciparum serine repeat antigen 1 0.039 0.0742 0.2433
Schistosoma mansoni reticulocalbin 0.0225 0.0402 0.04
Echinococcus granulosus apoptotic protease activating factor 1 0.018 0.0308 0.0306
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0034 0.0005 0.0011
Echinococcus multilocularis calpain 7 (C02 family) 0.14 0.2835 0.2834
Chlamydia trachomatis glycogen phosphorylase 0.012 0.0183 0.5
Trypanosoma brucei antigen, putative 0.14 0.2835 0.6735
Leishmania major kinesin, putative 0.0991 0.1987 0.472
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Plasmodium falciparum plasmepsin VIII, putative 0.0043 0.0025 0.0076
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0838 0.1672 0.397
Loa Loa (eye worm) PAS-3 protein 0.0041 0.0019 0.0019
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0041 0.0019 0.0018
Schistosoma mansoni patched 1 0.0599 0.1175 0.1174
Loa Loa (eye worm) hypothetical protein 0.1051 0.2112 0.2112
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0141 0.014
Toxoplasma gondii EF hand domain-containing protein 0.0222 0.0394 0.0937
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Trichomonas vaginalis centrin, putative 0.0222 0.0394 0.1089
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0166 0.0279 0.0277
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0253 0.0459 0.127
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Echinococcus granulosus Transglutaminase 0.0291 0.0538 0.0536
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0041 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0361 0.0682 0.0682
Brugia malayi Trypsin family protein 0.0166 0.0279 0.0279
Loa Loa (eye worm) cathepsin B 0.1772 0.3605 0.3605
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0002 0.0002
Schistosoma mansoni z-protein (S1r protein) 0.0045 0.0027 0.0026
Trichomonas vaginalis set domain proteins, putative 0.0804 0.16 0.4434
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0253 0.0459 0.1088
Trypanosoma cruzi I/6 autoantigen, putative 0.0222 0.0394 0.0393
Giardia lamblia 20S proteasome alpha subunit 6 0.0041 0.0019 0.0049
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0041 0.0019 0.0058
Schistosoma mansoni mitochondrial solute carrier 0.0222 0.0394 0.0393
Brugia malayi Cathepsin L-like precursor 0.1051 0.2112 0.2112
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0041 0.0019 0.0042
Loa Loa (eye worm) hypothetical protein 0.0166 0.0279 0.0279
Toxoplasma gondii preprocathepsin c precursor, putative 0.039 0.0742 0.1764
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Echinococcus granulosus cathepsin L 0.084 0.1676 0.1675
Leishmania major cysteine peptidase A (CPA) 0.1502 0.3046 0.7237
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1502 0.3046 0.3045
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0041 0.0019 0.0042
Brugia malayi calpain 7 0.14 0.2835 0.2835
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0139 0.0223 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1502 0.3046 0.8447
Giardia lamblia Proteasome subunit beta type 2 0.0092 0.0126 0.0344
Echinococcus granulosus subfamily T1A non peptidase ue 0.0041 0.0019 0.0018
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0041 0.0019 0.0058
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0018 0.0057
Onchocerca volvulus Cell death protein 3 homolog 0.0267 0.0488 0.1021
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0071
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0592 0.1162 0.1161
Entamoeba histolytica hypothetical protein 0.039 0.0742 0.2433
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0115 0.0372
Echinococcus granulosus cathepsin L cysteine proteinase 0.1502 0.3046 0.3045
Schistosoma mansoni microtubule-associated protein tau 0.1592 0.3233 0.3232
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.0119 0.0325
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0041 0.0019 0.0019
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0041 0.0019 0.0018
Schistosoma mansoni regulator of G protein signaling 0.0045 0.0027 0.0026
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0222 0.0394 0.0393
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0233 0.0231
Echinococcus multilocularis Regulator of G protein signaling 20 0.0045 0.0027 0.0026
Leishmania major proteasome beta-1 subunit, putative 0.0041 0.0019 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.6735
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0041 0.0019 0.0018
Giardia lamblia Hypothetical protein 0.0291 0.0538 0.1488
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0041 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0409 0.0782 0.2166
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0018
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0013 0.0012
Brugia malayi cahepsin L-like non-peptiedase homolog 0.039 0.0742 0.0742
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0041 0.0019 0.0058
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Brugia malayi Cathepsin L-like precursor 0.1502 0.3046 0.3046
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0041 0.0019 0.0058
Schistosoma mansoni hypothetical protein 0.018 0.0308 0.0306
Schistosoma mansoni cpg binding protein 0.0034 0.0005 0.0004
Brugia malayi calpain D 0.0409 0.0782 0.0782
Loa Loa (eye worm) hypothetical protein 0.0043 0.0025 0.0025
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Trypanosoma brucei centrin, putative 0.0222 0.0394 0.0933
Trichomonas vaginalis calcium binding proteins, putative 0.0222 0.0394 0.1089
Echinococcus multilocularis regulator of G protein signaling 0.0045 0.0027 0.0026
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0166 0.0279 0.0277
Onchocerca volvulus Cathepsin L homolog 0.039 0.0742 0.1553
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0041 0.0019 0.0018
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Leishmania major hypothetical protein, unknown function 0.0409 0.0782 0.1856
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0243 0.0439 0.1436
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0115 0.0314
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0682 0.1348 0.3737
Echinococcus granulosus Protein patched homolog 1 0.0599 0.1175 0.1174
Echinococcus granulosus cysteine protease 0.084 0.1676 0.1675
Trichomonas vaginalis centrin, putative 0.0222 0.0394 0.1089
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0253 0.0459 0.127
Loa Loa (eye worm) hypothetical protein 0.0101 0.0144 0.0144
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.039 0.0742 0.0741
Echinococcus multilocularis calpain family protein 1, d 0.2747 0.5627 0.5627
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0222 0.0394 0.0393
Schistosoma mansoni ef hand domain family member A2 0.0222 0.0394 0.0393
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0013 0.0032
Echinococcus granulosus regulator of G protein signaling 3 0.0045 0.0027 0.0026
Giardia lamblia Cathepsin B precursor 0.1772 0.3605 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0027 0.0071
Schistosoma mansoni hypothetical protein 0.0222 0.0394 0.0393
Brugia malayi cathepsin F-like cysteine proteinase 0.0451 0.0869 0.0869
Brugia malayi histone deacetylase 11 0.0043 0.0023 0.0023
Echinococcus multilocularis inhibitor of apoptosis protein 0.0187 0.0322 0.0321
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.084 0.1676 0.1675
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.039 0.0742 0.2433
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4858 1 1
Echinococcus multilocularis neurocalcin 0.0222 0.0394 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.084 0.1676 0.4647
Trypanosoma cruzi cruzipain precursor, putative 0.1611 0.3273 0.3272
Echinococcus multilocularis caspase 8 0.0087 0.0115 0.0113
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0087 0.0115 0.0115
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0143 0.023 0.0617
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0041 0.0019 0.0049
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0043 0.0025 0.0064
Onchocerca volvulus Deterin homolog 0.0187 0.0322 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.0409 0.0782 0.2166
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0041 0.0019 0.0049
Schistosoma mansoni centrin 0.0222 0.0394 0.0393
Toxoplasma gondii cathepsin CPC1 0.039 0.0742 0.1764
Brugia malayi Regulator of G protein signaling domain containing protein 0.0045 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.0038 0.0013 0.004
Onchocerca volvulus 0.1502 0.3046 0.6372
Onchocerca volvulus 0.0178 0.0304 0.0636
Echinococcus granulosus endothelin converting enzyme 1 0.0101 0.0144 0.0143
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.039 0.0742 0.0741
Brugia malayi proteasome subunit alpha type 1 0.0041 0.0019 0.0019
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0132 0.0208 0.0677
Brugia malayi hypothetical protein 0.0178 0.0304 0.0304
Toxoplasma gondii proteasome subunit beta type, putative 0.0253 0.0459 0.1092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Schistosoma mansoni hypothetical protein 0.0166 0.0279 0.0277
Giardia lamblia 20S proteasome alpha subunit 4 0.0041 0.0019 0.0049
Plasmodium falciparum histone deacetylase 2 0.01 0.0141 0.0459
Toxoplasma gondii aspartyl protease ASP1 0.0043 0.0025 0.0059
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0001 0.0001
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0042 0.0133
Echinococcus granulosus beta-adrenergic receptor kinase 0.0045 0.0027 0.0026
Trypanosoma brucei calpain-like protein, putative 0.14 0.2835 0.6735
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Loa Loa (eye worm) ctsf protein 0.1502 0.3046 0.3046
Onchocerca volvulus Peroxidase homolog 0.0325 0.0608 0.1273
Loa Loa (eye worm) proteasome subunit beta type 2 0.0092 0.0126 0.0126
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.1454 0.2948 0.2947
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0233 0.0231
Trypanosoma cruzi caltractin, putative 0.0222 0.0394 0.0393
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0416 0.0796 0.0795
Leishmania major proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0042
Loa Loa (eye worm) hypothetical protein 0.0038 0.0013 0.0013
Schistosoma mansoni calpain-7 (C02 family) 0.1403 0.2841 0.284
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0222 0.0394 0.0393
Leishmania major cathepsin L-like protease 0.1502 0.3046 0.7237
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Plasmodium vivax centrin-1, putative 0.0222 0.0394 0.129
Toxoplasma gondii proteasome subunit 0.0041 0.0019 0.0046
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0223 0.0613
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0166 0.0279 0.0277
Echinococcus granulosus caspase 2 0.0267 0.0488 0.0487
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0041 0.0019 0.0049
Mycobacterium ulcerans aldehyde dehydrogenase 0.0143 0.023 0.0775
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.039 0.0742 0.0742
Schistosoma mansoni glycogen phosphorylase 0.012 0.0183 0.0182
Plasmodium vivax vivapain-3 0.084 0.1676 0.5501
Mycobacterium ulcerans proteasome PrcA 0.0041 0.0019 0.006
Loa Loa (eye worm) hypothetical protein 0.0451 0.0869 0.0869
Trypanosoma brucei Calpain-like protein CALP1.3 0.0409 0.0782 0.1856
Toxoplasma gondii histone deacetylase HDAC1 0.01 0.0141 0.0336
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Plasmodium falciparum serine repeat antigen 9 0.039 0.0742 0.2433
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0045 0.0027 0.0027
Echinococcus multilocularis proteasome (prosome, macropain) 0.0253 0.0459 0.0458
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4858 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0243 0.0439 0.0437
Loa Loa (eye worm) hypothetical protein 0.0089 0.0119 0.0119
Toxoplasma gondii peptidase family M13 protein 0.0101 0.0144 0.0342
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1161 0.2339 0.2338
Brugia malayi proteasome subunit alpha type 4 0.0041 0.0019 0.0019
Brugia malayi hypothetical protein 0.0166 0.0279 0.0279
Echinococcus granulosus proteasome subunit beta t family 0.0041 0.0019 0.0018
Echinococcus multilocularis centrin 2 0.0222 0.0394 0.0393
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0253 0.0459 0.2689
Trypanosoma cruzi metacaspase, putative 0.0087 0.0115 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1051 0.2112 0.5856
Brugia malayi Trypsin family protein 0.0166 0.0279 0.0279
Brugia malayi EF hand family protein 0.0225 0.0402 0.0402
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Giardia lamblia Hypothetical protein 0.0225 0.0402 0.1111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1611 0.3273 0.7778
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0041 0.0019 0.0042
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0222 0.0394 0.129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Echinococcus granulosus inhibitor of apoptosis protein 0.0187 0.0322 0.0321
Echinococcus granulosus histone deacetylase 3 0.0089 0.0119 0.0117
Onchocerca volvulus 0.0058 0.0056 0.0116
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0013 0.0012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0087 0.0115 0.0314
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0019 0.0049
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0051 0.004 0.0039
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0409 0.0782 0.2166
Loa Loa (eye worm) hypothetical protein 0.0451 0.0869 0.0869
Loa Loa (eye worm) hypothetical protein 0.0043 0.0023 0.0023
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1502 0.3046 0.3045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1051 0.2112 0.5856
Plasmodium vivax histone deacetylase, putative 0.0043 0.0023 0.0072
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0126 0.0195 0.046
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0045 0.0027 0.0026
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0126 0.0195 0.0193
Loa Loa (eye worm) papain family cysteine protease containing protein 0.039 0.0742 0.0742
Loa Loa (eye worm) calmodulin-like protein 0.0222 0.0394 0.0394
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0409 0.0782 0.1856
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0145 0.0236 0.0234
Trichomonas vaginalis hypothetical protein 0.0409 0.0782 0.2166
Echinococcus multilocularis protein dispatched 1 0.0599 0.1175 0.1174
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0018 0.0047
Trypanosoma cruzi 20S proteasome subunit 0.0092 0.0126 0.0124
Echinococcus multilocularis proteasome subunit alpha type 6 0.0041 0.0019 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.084 0.1676 0.1675
Echinococcus granulosus neuronal calcium sensor 0.0222 0.0394 0.0393
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.0223 0.0613
Echinococcus granulosus Dipeptidyl peptidase 9 0.0341 0.064 0.0639
Echinococcus granulosus Regulator of G protein signaling 20 0.0045 0.0027 0.0026
Onchocerca volvulus 0.0038 0.0013 0.0028
Giardia lamblia Dipeptidyl-peptidase I precursor 0.039 0.0742 0.2055
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0341 0.064 0.0639
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0416 0.0796 0.0795
Echinococcus granulosus histone deacetylase 6 0.0106 0.0154 0.0153
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0041 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1502 0.3046 0.8447
Schistosoma mansoni inhibitor of apoptosis protein 0.0187 0.0322 0.0321
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0023 0.0022
Mycobacterium leprae Conserved hypothetical protein 0.0291 0.0538 0.3163
Echinococcus multilocularis tumor protein p63 0.0399 0.0761 0.0759
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.084 0.1676 0.3981
Loa Loa (eye worm) PXA domain-containing protein 0.0045 0.0027 0.0027
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Giardia lamblia Cysteine protease 0.039 0.0742 0.2055
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0041 0.0019 0.0058
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.14 0.2835 0.6735
Trichomonas vaginalis conserved hypothetical protein 0.0222 0.0394 0.1089
Loa Loa (eye worm) hypothetical protein 0.0282 0.052 0.052
Brugia malayi proteasome subunit beta type 3 0.0041 0.0019 0.0019
Onchocerca volvulus 0.1502 0.3046 0.6372
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0341 0.064 0.1519
Schistosoma mansoni Mername-AA248 (C02 family) 0.14 0.2835 0.2834
Echinococcus granulosus tumor protein p63 0.0399 0.0761 0.0759
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0041 0.0019 0.0019
Echinococcus multilocularis histone deacetylase 3 0.0089 0.0119 0.0117
Echinococcus granulosus regulator of G protein signaling 7 0.0045 0.0027 0.0026
Entamoeba histolytica cysteine proteinase, putative 0.084 0.1676 0.5501
Brugia malayi Papain family cysteine protease containing protein 0.039 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.0451 0.0869 0.0869
Trypanosoma brucei proteasome beta 7 subunit 0.0041 0.0019 0.0042
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0041 0.0019 0.0019
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.1454 0.2948 0.2947
Loa Loa (eye worm) hypothetical protein 0.0058 0.0056 0.0056
Trypanosoma cruzi conserved protein 0.0409 0.0782 0.0781
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0141 0.014
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0682 0.1348 0.3737
Schistosoma mansoni hypothetical protein 0.0409 0.0782 0.0781
Schistosoma mansoni chromatin regulatory protein sir2 0.0126 0.0195 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.084 0.1676 0.4647
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0041 0.0019 0.0019
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.024 0.0662
Leishmania major calmodulin, putative 0.0222 0.0394 0.0933
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0013 0.0033
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.0781
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Loa Loa (eye worm) hypothetical protein 0.0075 0.0089 0.0089
Trypanosoma cruzi centrin-3 0.0229 0.0409 0.0408
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0041 0.0019 0.0018
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0041 0.0019 0.0018
Leishmania major histone deacetylase, putative 0.01 0.0141 0.0332
Trypanosoma cruzi kinesin, putative 0.0991 0.1987 0.1986
Echinococcus multilocularis Glycosyl transferase, family 35 0.012 0.0183 0.0182
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0243 0.0439 0.1436
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0018 0.004
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0143 0.023 0.0543
Trypanosoma cruzi cysteine peptidase, putative 0.1611 0.3273 0.3272
Echinococcus granulosus proteasome subunit alpha type 6 0.0041 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.1454 0.2948 0.2948
Onchocerca volvulus Peroxidase homolog 0.0325 0.0608 0.1273
Leishmania major i/6 autoantigen-like protein 0.0222 0.0394 0.0933
Loa Loa (eye worm) CYP4Cod1 0.0037 0.0011 0.0011
Trypanosoma brucei metacaspase MCA3 0.0087 0.0115 0.0269
Echinococcus granulosus neurocalcin 0.0222 0.0394 0.0393
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.14 0.2835 0.6735
Loa Loa (eye worm) calpain family protein 1 0.3738 0.768 0.768
Schistosoma mansoni calmodulin related calcium binding protein 0.0222 0.0394 0.0393
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0093
Trypanosoma cruzi cysteine peptidase, putative 0.1502 0.3046 0.3045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Brugia malayi Calmodulin-like protein 0.0222 0.0394 0.0394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Trypanosoma brucei proteasome beta 6 subunit 0.0145 0.0236 0.0557
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0409 0.0782 0.0781
Brugia malayi Proteasome A-type and B-type family protein 0.0253 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.039 0.0742 0.2055
Leishmania major proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0042
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0023 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.039 0.0742 0.0742
Brugia malayi Pepsin A precursor 0.0043 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0036
Plasmodium vivax unspecified product 0.039 0.0742 0.2433
Leishmania major hypothetical protein, conserved 0.0049 0.0036 0.0081
Onchocerca volvulus 0.0225 0.0402 0.084
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0041 0.0019 0.0058
Brugia malayi CHE-14 protein 0.0599 0.1175 0.1175
Brugia malayi aspartic protease BmAsp-2, identical 0.0043 0.0025 0.0025
Echinococcus multilocularis EF hand domain containing family member A2 0.0225 0.0402 0.04
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0043 0.0025 0.0025
Trichomonas vaginalis calmodulin-2, putative 0.0222 0.0394 0.1089
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0166 0.0279 0.0277
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0041 0.0019 0.0048
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0041 0.0019 0.0058
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0838 0.1672 0.167
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0706 0.1398 0.1398
Loa Loa (eye worm) hypothetical protein 0.0076 0.0093 0.0093
Leishmania major proteasome beta 5 subunit, putative 0.0253 0.0459 0.1088
Echinococcus multilocularis calmodulin 0.0222 0.0394 0.0393
Echinococcus granulosus tissue type plasminogen activator 0.0049 0.0036 0.0034
Echinococcus granulosus EF HAND 1 calcium binding site 0.0222 0.0394 0.0393
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.039 0.0742 0.0741
Brugia malayi Cathepsin L-like precursor 0.1502 0.3046 0.3046
Echinococcus granulosus calbindin 32 0.0225 0.0402 0.04
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0043 0.0025 0.0023
Onchocerca volvulus 0.1502 0.3046 0.6372
Loa Loa (eye worm) prolyl oligopeptidase 0.0592 0.1162 0.1162
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0084 0.0083
Leishmania major cathepsin L-like protease 0.1611 0.3273 0.7778
Onchocerca volvulus 0.0166 0.0279 0.0583
Schistosoma mansoni rab 0.0222 0.0394 0.0393
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.0119 0.0325
Entamoeba histolytica cysteine protease, putative 0.084 0.1676 0.5501
Loa Loa (eye worm) hypothetical protein 0.039 0.0742 0.0742
Plasmodium vivax histone deacetylase 2, putative 0.01 0.0141 0.0459
Echinococcus multilocularis GPI anchor transamidase 0.0034 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.3329 0.6832 0.6832
Loa Loa (eye worm) hypothetical protein 0.0267 0.0488 0.0488
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0592 0.1162 0.2431
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0013 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.0166 0.0279 0.0277
Brugia malayi fibroinase precursor 0.039 0.0742 0.0742
Brugia malayi prolyl oligopeptidase family protein 0.0592 0.1162 0.1162
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0041 0.0019 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.1502 0.3046 1
Echinococcus multilocularis calmodulin 0.0222 0.0394 0.0393
Giardia lamblia Cathepsin L-like protease 0.039 0.0742 0.2055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0409 0.0782 0.0781
Echinococcus multilocularis histone deacetylase 6 0.01 0.0141 0.014
Leishmania major calmodulin, putative 0.0222 0.0394 0.0933
Loa Loa (eye worm) hypothetical protein 0.005 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1502 0.3046 0.8447
Echinococcus granulosus cathepsin b 0.4858 1 1
Echinococcus multilocularis histone deacetylase 6 0.01 0.0141 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.039 0.0742 0.2055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1772 0.3605 0.3604
Onchocerca volvulus 0.0222 0.0394 0.0825
Entamoeba histolytica cysteine proteinase 2 0.084 0.1676 0.5501
Trichomonas vaginalis calcium binding protein, putative 0.0222 0.0394 0.1089
Plasmodium falciparum plasmepsin VI 0.0043 0.0025 0.0076
Plasmodium falciparum metacaspase-like protein 0.0087 0.0115 0.0372
Giardia lamblia Alanyl dipeptidyl peptidase 0.0243 0.0439 0.1213
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0027
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0599 0.1175 0.1175
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0013 0.0013
Echinococcus multilocularis sterol regulatory element binding protein 0.0599 0.1175 0.1174
Loa Loa (eye worm) hypothetical protein 0.0325 0.0608 0.0608
Onchocerca volvulus Legumain homolog 0.0147 0.024 0.0502
Mycobacterium tuberculosis Long conserved protein 0.0291 0.0538 0.1448
Mycobacterium tuberculosis Probable peptidase 0.0838 0.1672 0.451
Trypanosoma cruzi calmodulin, putative 0.0222 0.0394 0.0393
Onchocerca volvulus Dual oxidase homolog 0.0325 0.0608 0.1273
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0019 0.0049
Onchocerca volvulus 0.0325 0.0608 0.1273
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0243 0.0439 0.1042
Toxoplasma gondii heat shock protein hslv, putative 0.0041 0.0019 0.0046
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0222 0.0394 0.1089
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0166 0.0279 0.0279
Mycobacterium tuberculosis Conserved protein 0.0038 0.0013 0.0032
Echinococcus granulosus calpain A 0.14 0.2835 0.2834
Trypanosoma cruzi major cysteine proteinase, putative 0.039 0.0742 0.0741
Giardia lamblia Histone deacetylase 0.0089 0.0119 0.0325
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.039 0.0742 0.0741
Giardia lamblia Cathepsin L precursor 0.039 0.0742 0.2055
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0018 0.0017
Echinococcus multilocularis cathepsin L 0.039 0.0742 0.0741
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.024 0.0239
Brugia malayi Trypsin family protein 0.0166 0.0279 0.0279
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0051 0.004 0.0039
Plasmodium vivax histone deacetylase, putative 0.01 0.0141 0.0459
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0041 0.0019 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1502 0.3046 0.8447
Trypanosoma brucei oligopeptidase b 0.0838 0.1672 0.397
Loa Loa (eye worm) transcriptional regulator 0.0126 0.0195 0.0195
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0041 0.0019 0.0058
Schistosoma mansoni neuronal calcium sensor 0.0222 0.0394 0.0393
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.039 0.0742 0.2433
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0409 0.0782 0.1856
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0222 0.0394 0.129
Leishmania major hypothetical protein, conserved 0.0222 0.0394 0.0933
Schistosoma mansoni chromatin regulatory protein sir2 0.0139 0.0223 0.0221
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0341 0.064 0.1519
Echinococcus multilocularis Mastin 0.0166 0.0279 0.0277
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0041 0.0019 0.0058
Leishmania major cathepsin L-like protease 0.1502 0.3046 0.7237
Brugia malayi GPI-anchor transamidase 0.0034 0.0005 0.0005
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0409 0.0782 0.1856
Schistosoma mansoni chromatin regulatory protein sir2 0.0126 0.0195 0.0193
Toxoplasma gondii calmodulin CAM1 0.0225 0.0402 0.0955
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.396 0.8139 0.8139
Plasmodium vivax serine-repeat antigen (SERA) 0.039 0.0742 0.2433
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0608 0.0608
Plasmodium vivax proteasome subunit beta type-2, putative 0.0092 0.0126 0.0407
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.1454 0.2948 0.7004
Brugia malayi Animal haem peroxidase family protein 0.0325 0.0608 0.0608
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0002 0.0002
Echinococcus multilocularis cpg binding protein 0.0034 0.0005 0.0004
Plasmodium falciparum cysteine proteinase falcipain 1 0.084 0.1676 0.5501
Trypanosoma brucei histone deacetylase 4 0.01 0.0141 0.0332
Toxoplasma gondii prolyl endopeptidase 0.2062 0.4208 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0102 0.0146 0.0144
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0041 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0178 0.0304 0.0304
Leishmania major histone deacetylase, putative 0.01 0.0141 0.0332
Onchocerca volvulus 0.0325 0.0608 0.1273
Brugia malayi MH2 domain containing protein 0.013 0.0203 0.0203
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0023 0.0022
Echinococcus multilocularis survival motor neuron protein 1 0.0282 0.052 0.0518
Toxoplasma gondii centrin 0.0222 0.0394 0.0937
Leishmania major centrin, putative,caltractin, putative 0.0222 0.0394 0.0933

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 18.1 mg kg-1 Anticonvulsant activity in mice by intraperitoneal administration measured at 30 mins before maximum electroshock seizure induction ChEMBL. 10406642
ED50 (functional) = 18.1 mg kg-1 Anticonvulsant activity in mice by intraperitoneal administration measured at 30 mins before maximum electroshock seizure induction ChEMBL. 10406642
ED50 (functional) = 50.8 mg kg-1 Anticonvulsant activity in mice by peroral administration measured at 60 mins before maximum electroshock seizure induction ChEMBL. 10406642
ED50 (functional) = 50.8 mg kg-1 Anticonvulsant activity in mice by peroral administration measured at 60 mins before maximum electroshock seizure induction ChEMBL. 10406642
ED50 (functional) = 176 mg kg-1 Psychomotor side-effect in mice by rotorod test by intraperitoneal administration at 60 mins ChEMBL. 10406642
ED50 (functional) = 176 mg kg-1 Psychomotor side-effect in mice by rotorod test by intraperitoneal administration at 60 mins ChEMBL. 10406642
IC50 (binding) = 2.6 uM Binding of [3H]-batrachotoxin (BTX) to rat brain sodium channel ChEMBL. 10406642
IC50 (binding) = 2.6 uM Binding of [3H]-batrachotoxin (BTX) to rat brain sodium channel ChEMBL. 10406642
IC50 (binding) > 300 uM Binding of [3H]-saxitoxin (STX) to rat brain sodium channel ChEMBL. 10406642
IC50 (binding) > 300 uM Binding of [3H]-saxitoxin (STX) to rat brain sodium channel ChEMBL. 10406642
TI (functional) = 10 Therapeutic index TI (ED50 rotorod/MES) of the compound ChEMBL. 10406642

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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