Detailed information for compound 917308

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 357.877 | Formula: C20H24ClN3O
  • H donors: 3 H acceptors: 1 LogP: 3.52 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCCN1CCc2c(C1c1cccc(c1)O)[nH]c1c2cc(cc1)C.Cl
  • InChi: 1S/C20H23N3O.ClH/c1-13-5-6-18-17(11-13)16-7-9-23(10-8-21)20(19(16)22-18)14-3-2-4-15(24)12-14;/h2-6,11-12,20,22,24H,7-10,21H2,1H3;1H
  • InChiKey: ILZIULCMOOXKIH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens kinesin family member 11 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica kinesin, putative Get druggable targets OG5_128460 All targets in OG5_128460
Neospora caninum hypothetical protein Get druggable targets OG5_128460 All targets in OG5_128460
Schistosoma japonicum ko:K10398 kinesin family member 11, putative Get druggable targets OG5_128460 All targets in OG5_128460
Schistosoma mansoni kinesin eg-5 Get druggable targets OG5_128460 All targets in OG5_128460
Plasmodium knowlesi kinesin-5, putative Get druggable targets OG5_128460 All targets in OG5_128460
Plasmodium falciparum kinesin-5 Get druggable targets OG5_128460 All targets in OG5_128460
Plasmodium vivax kinesin-5 Get druggable targets OG5_128460 All targets in OG5_128460
Cryptosporidium hominis kinesin-like boursin Get druggable targets OG5_128460 All targets in OG5_128460
Giardia lamblia Kinesin-5 Get druggable targets OG5_128460 All targets in OG5_128460
Brugia malayi Kinesin motor domain containing protein Get druggable targets OG5_128460 All targets in OG5_128460
Plasmodium yoelii Kinesin motor domain, putative Get druggable targets OG5_128460 All targets in OG5_128460
Toxoplasma gondii kinesin motor domain-containing protein Get druggable targets OG5_128460 All targets in OG5_128460
Plasmodium berghei kinesin-5, putative Get druggable targets OG5_128460 All targets in OG5_128460
Loa Loa (eye worm) kinesin-like protein KLP2 Get druggable targets OG5_128460 All targets in OG5_128460
Cryptosporidium parvum kinesin-like boursin, putative Get druggable targets OG5_128460 All targets in OG5_128460
Echinococcus multilocularis kinesin family 1 Get druggable targets OG5_128460 All targets in OG5_128460
Candida albicans kinesin motor domain protein similar to S. cerevisiae KIP1 (YBL063W) microtubule motor complex protein Get druggable targets OG5_128460 All targets in OG5_128460
Candida albicans kinesin motor domain protein similar to S. cerevisiae KIP1 (YBL063W) microtubule motor complex protein Get druggable targets OG5_128460 All targets in OG5_128460
Echinococcus granulosus kinesin family 1 Get druggable targets OG5_128460 All targets in OG5_128460
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Kelch motif family protein 0.0047 0.0202 0.0214
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0104 0.011
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0049 0.0231 0.0377
Echinococcus granulosus cpg binding protein 0.003 0.0018 0.0011
Schistosoma mansoni cathepsin B (C01 family) 0.0083 0.0605 0.0606
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0876 0.9441 0.9448
Brugia malayi beta-lactamase 0.0072 0.0481 0.051
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0326 0.3313 0.3519
Brugia malayi Animal haem peroxidase family protein 0.0419 0.4344 0.4601
Loa Loa (eye worm) integrin alpha pat-2 0.0232 0.2268 0.2403
Trypanosoma cruzi caltractin, putative 0.0049 0.0231 0.0215
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.3362 0.3571
Loa Loa (eye worm) calmodulin-like protein 0.0049 0.0231 0.0244
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0338 0.0331
Echinococcus multilocularis integrin alpha 3 0.0116 0.0967 0.096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.037 0.037
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0045 0.0178 0.0488
Brugia malayi Calcium binding EGF domain containing protein 0.0049 0.0224 0.0238
Schistosoma mansoni cathepsin F (C01 family) 0.0238 0.2327 0.2328
Schistosoma mansoni caspase-7 (C14 family) 0.0244 0.2402 0.2404
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0231 0.0377
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0326 0.3313 0.7277
Echinococcus multilocularis calpain family protein 1, d 0.0645 0.6866 0.6863
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0717 0.071
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0155 0.1402 0.2861
Trypanosoma cruzi cruzipain precursor, putative 0.0436 0.4542 0.4835
Onchocerca volvulus 0.0156 0.1418 0.2462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Leishmania major calcineurin B subunit, putative 0.0049 0.0231 0.0445
Schistosoma mansoni calmodulin 0.0049 0.0231 0.0231
Trypanosoma brucei calmodulin, putative 0.0049 0.0231 0.0493
Trypanosoma brucei calpain, putative 0.0099 0.0786 0.1718
Leishmania major oligopeptidase b 0.0052 0.0261 0.0512
Plasmodium falciparum serine repeat antigen 3 0.0083 0.0605 0.1712
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0104 0.0104
Schistosoma mansoni notch 0.0049 0.0224 0.0224
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Trypanosoma brucei metacaspase 5, putative 0.0123 0.1045 0.2289
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0481 0.0927
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0328 0.0887
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0865 0.0858
Loa Loa (eye worm) hypothetical protein 0.0152 0.137 0.1451
Loa Loa (eye worm) TK/ROR protein kinase 0.0068 0.0434 0.046
Echinococcus multilocularis transmembrane protease serine 3 0.0156 0.1418 0.1411
Trypanosoma brucei I/6 autoantigen 0.0049 0.0231 0.0493
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0126 0.108 0.1126
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0178 0.0272
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0052 0.0261 0.0512
Echinococcus multilocularis integrin alpha ps 0.0068 0.0432 0.0425
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0083 0.0605 0.0606
Trypanosoma brucei kinesin, putative 0.0231 0.2255 0.4956
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Onchocerca volvulus 0.0156 0.1418 0.2462
Trypanosoma cruzi calmodulin, putative 0.0049 0.0231 0.0215
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0131 0.1142 0.1142
Brugia malayi Cathepsin L-like precursor 0.0343 0.35 0.3707
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0605 0.1116
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0188 0.1779 0.178
Schistosoma mansoni hypothetical protein 0.041 0.4246 0.4249
Schistosoma mansoni ets-related 0.0225 0.219 0.2192
Giardia lamblia Cathepsin L precursor 0.0083 0.0605 0.1733
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0481 0.3253
Echinococcus multilocularis fibropellin Ia 0.0049 0.0224 0.0217
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0104 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1045 0.1984
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0605 0.1116
Schistosoma mansoni mitochondrial solute carrier 0.0049 0.0231 0.0231
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.004 0.0071
Giardia lamblia Hypothetical protein 0.0126 0.108 0.3184
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0052 0.0261 0.0247
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1718
Trypanosoma cruzi metacaspase, putative 0.0123 0.1045 0.1088
Echinococcus multilocularis apoptotic protease activating factor 1 0.0122 0.1036 0.103
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0104 0.0096
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Echinococcus granulosus calpain 7 C02 family 0.0331 0.3362 0.3357
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0104 0.0096
Schistosoma mansoni septate junction protein 0.0049 0.0224 0.0224
Trypanosoma cruzi hypothetical protein, conserved 0.0068 0.0434 0.0433
Entamoeba histolytica calpain large subunit domain III containing protein 0.0231 0.2255 0.6403
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0865 0.1628
Onchocerca volvulus 0.0238 0.2327 0.404
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Echinococcus granulosus calpain 5 0.0331 0.3362 0.3357
Toxoplasma gondii troponin c, isotype gamma, putative 0.0049 0.0231 0.0639
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0083 0.0605 0.1116
Echinococcus granulosus calcium uptake protein 1 0.005 0.0238 0.0231
Toxoplasma gondii aspartyl protease ASP3 0.0323 0.3278 0.9363
Loa Loa (eye worm) hypothetical protein 0.0068 0.0434 0.046
Loa Loa (eye worm) hypothetical protein 0.0238 0.2327 0.2464
Leishmania major silent information regulator 2, putative 0.0126 0.108 0.2328
Echinococcus multilocularis centrin 2 0.0049 0.0231 0.0224
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0111 0.0914 0.0908
Echinococcus granulosus protein jagged 2 0.0049 0.0224 0.0217
Schistosoma mansoni peroxidasin 0.0419 0.4344 0.4347
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0605 0.1116
Echinococcus multilocularis calpain A 0.0927 1 1
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.004 0.0092
Schistosoma mansoni integrin beta subunit 0.0182 0.1705 0.1706
Toxoplasma gondii hypothetical protein 0.0099 0.0786 0.223
Loa Loa (eye worm) hypothetical protein 0.0126 0.1083 0.1147
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0605 0.0606
Schistosoma mansoni cathepsin s 0.0105 0.0853 0.0854
Brugia malayi Animal haem peroxidase family protein 0.0419 0.4344 0.4601
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0481 0.0484
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0083 0.0605 0.1712
Onchocerca volvulus 0.0343 0.35 0.6078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.037 0.0363
Echinococcus multilocularis neural cadherin 0.0049 0.0224 0.0217
Leishmania major hypothetical protein, conserved 0.0049 0.0231 0.0445
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Loa Loa (eye worm) hypothetical protein 0.0131 0.1142 0.1209
Brugia malayi Pepsin A precursor 0.0075 0.0513 0.0543
Echinococcus granulosus transmembrane protease serine 3 0.0156 0.1418 0.1411
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Echinococcus multilocularis integrin alpha ps 0.0068 0.0432 0.0425
Trichomonas vaginalis centrin, putative 0.0049 0.0231 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0104 0.0126
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0083 0.0605 0.164
Echinococcus granulosus delta-like protein 1 0.0049 0.0224 0.0217
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0328 0.0321
Leishmania major proteasome beta 2 subunit, putative 0.0045 0.0178 0.0327
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.004 0.0032
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0099 0.0786 0.1473
Echinococcus multilocularis cathepsin b 0.0869 0.936 0.936
Schistosoma mansoni hypothetical protein 0.0314 0.318 0.3183
Brugia malayi hypothetical protein 0.0126 0.1083 0.1147
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0192 0.0446
Schistosoma mansoni kinesin eg-5 0.0032 0.0037 0.0038
Plasmodium vivax unspecified product 0.0083 0.0605 0.1712
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0104 0.0096
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0231 0.0377
Onchocerca volvulus 0.0419 0.4344 0.7543
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0105 0.0853 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0104 0.0126
Plasmodium falciparum plasmepsin I 0.0111 0.0914 0.2597
Brugia malayi calpain 5 0.0231 0.2255 0.2388
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0155 0.1402 0.4167
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0155 0.1402 0.3942
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0238 0.2327 0.4512
Brugia malayi Trypsin family protein 0.0156 0.1418 0.1502
Trypanosoma brucei metacaspase MCA2 0.0123 0.1045 0.2289
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0331 0.3362 0.3571
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0111 0.0914 0.2597
Brugia malayi calpain family protein 1 0.0876 0.9441 1
Loa Loa (eye worm) EF hand family protein 0.0049 0.0231 0.0244
Trypanosoma cruzi kinesin, putative 0.0231 0.2255 0.2384
Echinococcus granulosus protein jagged 2 0.0049 0.0224 0.0217
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0328 0.0606
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0083 0.0605 0.1116
Mycobacterium ulcerans hypothetical protein 0.0156 0.1418 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0331 0.3362 0.3357
Leishmania major metacaspase, putative 0.0123 0.1045 0.225
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Trypanosoma brucei mitochondrial calcium uptake 1 0.0049 0.0231 0.0493
Brugia malayi aspartic protease BmAsp-1, identical 0.0075 0.0513 0.0543
Echinococcus multilocularis kinesin family 1 0.0247 0.2436 0.2431
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0314 0.318 0.3368
Onchocerca volvulus 0.0156 0.1418 0.2462
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0126 0.108 0.1074
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Giardia lamblia Hypothetical protein 0.005 0.0238 0.0613
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.004 0.0092
Brugia malayi proteasome subunit beta type 2 0.0045 0.0178 0.0188
Leishmania major hypothetical protein, conserved 0.0099 0.0786 0.1677
Brugia malayi hypothetical protein 0.0047 0.0202 0.0214
Trypanosoma cruzi cysteine proteinase, putative 0.0188 0.1779 0.1874
Schistosoma mansoni cell polarity protein 0.0049 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Trypanosoma brucei cytochrome P450, putative 0.0031 0.003 0.005
Echinococcus granulosus integrin alpha 3 0.0116 0.0967 0.096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Brugia malayi Animal haem peroxidase family protein 0.0419 0.4344 0.4601
Trypanosoma cruzi prolyl endopeptidase 0.0131 0.1142 0.1191
Onchocerca volvulus Peroxidasin homolog 0.0419 0.4344 0.7543
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0506 0.05
Leishmania major centrin, putative 0.0049 0.0231 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.0231 0.0244
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0188 0.1779 0.178
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.037 0.0363
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) fibroinase 0.0343 0.35 0.3707
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0099 0.0786 0.1473
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Brugia malayi NAD-dependent deacetylase SIRT1 0.0139 0.1229 0.1302
Schistosoma mansoni notch 0.0049 0.0224 0.0224
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Plasmodium falciparum cysteine repeat modular protein 1 0.0068 0.0434 0.1222
Giardia lamblia High cysteine protein 0.0049 0.0224 0.057
Brugia malayi transcriptional regulator, Sir2 family protein 0.0126 0.108 0.1144
Echinococcus granulosus cathepsin l1 0.0238 0.2327 0.2321
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0343 0.35 1
Trypanosoma brucei Component of motile flagella 41 0.0049 0.0231 0.0493
Leishmania major cathepsin L-like protease 0.0436 0.4542 1
Echinococcus multilocularis snurportin 1 0.0314 0.318 0.3175
Brugia malayi Trypsin family protein 0.0156 0.1418 0.1502
Schistosoma mansoni cathepsin C 0.0083 0.0605 0.0606
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0049 0.0231 0.0493
Trypanosoma cruzi conserved protein 0.0099 0.0786 0.0811
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0104 0.0104
Onchocerca volvulus Cathepsin F homolog 0.0343 0.35 0.6078
Trichomonas vaginalis hypothetical protein 0.0099 0.0786 0.1473
Trypanosoma cruzi cysteine peptidase, putative 0.0343 0.35 0.3719
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0104 0.0104
Trypanosoma brucei calpain-like protein, putative 0.0331 0.3362 0.7398
Plasmodium falciparum cysteine proteinase falcipain 3 0.0343 0.35 1
Mycobacterium tuberculosis Probable peptidase 0.0052 0.0261 0.0465
Brugia malayi Animal haem peroxidase family protein 0.0419 0.4344 0.4601
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0049 0.0231 0.0215
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0328 0.0661
Trypanosoma brucei Calpain-like protein 2 0.0099 0.0786 0.1718
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.004 0.0006
Echinococcus multilocularis EF hand domain containing family member A2 0.0049 0.0231 0.0224
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Mycobacterium ulcerans lipase LipD 0.0072 0.0481 0.3253
Plasmodium falciparum serine repeat antigen 2 0.0083 0.0605 0.1712
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.004 0.0042
Giardia lamblia Cathepsin L-like protease 0.0083 0.0605 0.1733
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0083 0.0605 0.1733
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Onchocerca volvulus Peroxidasin homolog 0.0419 0.4344 0.7543
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0244 0.2402 0.2544
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0481 0.1045
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Leishmania major cathepsin L-like protease 0.0343 0.35 0.7692
Loa Loa (eye worm) hypothetical protein 0.0476 0.4983 0.5278
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0104 0.0096
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Schistosoma mansoni chromatin regulatory protein sir2 0.0126 0.108 0.1081
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0195 0.185 0.1844
Echinococcus granulosus dnaJ subfamily B 0.041 0.4246 0.4242
Toxoplasma gondii EFHC1, putative 0.0049 0.0231 0.0639
Toxoplasma gondii aspartyl protease 0.0075 0.0513 0.1447
Plasmodium vivax vivapain-2 0.0343 0.35 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0605 0.1116
Loa Loa (eye worm) calpain family protein 1 0.0645 0.6866 0.7272
Schistosoma mansoni notch 0.0049 0.0224 0.0224
Entamoeba histolytica calmodulin, putative 0.0049 0.0231 0.0558
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0231 0.0377
Schistosoma mansoni hypothetical protein 0.0122 0.1036 0.1037
Echinococcus granulosus neurocalcin 0.0049 0.0231 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.1779 0.3431
Echinococcus granulosus tumor protein p63 0.0678 0.7233 0.7231
Brugia malayi fibroinase precursor 0.0083 0.0605 0.0641
Echinococcus multilocularis caspase 2 0.0244 0.2402 0.2397
Loa Loa (eye worm) hypothetical protein 0.0038 0.0104 0.011
Onchocerca volvulus 0.0083 0.0605 0.1051
Giardia lamblia Hypothetical protein 0.0083 0.0605 0.1733
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0104 0.0096
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0049 0.0231 0.0493
Giardia lamblia Cathepsin B precursor 0.0083 0.0605 0.1733
Loa Loa (eye worm) sirtuin 4 0.0032 0.004 0.0042
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0052 0.0261 0.0247
Entamoeba histolytica cysteine protease, putative 0.0083 0.0605 0.164
Echinococcus granulosus protein jagged 1 0.0049 0.0224 0.0217
Trypanosoma cruzi metacaspase, putative 0.0123 0.1045 0.1088
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0869 0.936 0.9368
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1045 0.1984
Brugia malayi Peroxidasin 0.0419 0.4344 0.4601
Trypanosoma cruzi metacaspase 5, putative 0.0123 0.1045 0.1088
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.3362 0.3571
Onchocerca volvulus Huntingtin homolog 0.0126 0.1083 0.1881
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0083 0.0605 0.1116
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0331 0.3368 0.3578
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.004 0.0092
Toxoplasma gondii EF hand domain-containing protein 0.0049 0.0231 0.0639
Schistosoma mansoni notch 0.0049 0.0227 0.0227
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0481 0.0871
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0123 0.1045 0.2971
Echinococcus granulosus cathepsin b 0.0869 0.936 0.936
Onchocerca volvulus 0.0049 0.0224 0.0389
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Trypanosoma cruzi centrin, putative 0.0049 0.0231 0.0215
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0156 0.1418 0.1411
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0099 0.0786 0.0811
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0104 0.0104
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Echinococcus multilocularis integrin beta 2 0.0229 0.2228 0.2222
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0446 0.1255
Brugia malayi Cathepsin L-like precursor 0.0238 0.2327 0.2464
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0605 0.0606
Giardia lamblia Proteasome subunit beta type 2 0.0045 0.0178 0.0428
Trypanosoma cruzi metacaspase 5, putative 0.0123 0.1045 0.1088
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0446 0.1179
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Schistosoma mansoni chromatin regulatory protein sir2 0.0126 0.108 0.1081
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Leishmania major calmodulin, putative 0.0049 0.0231 0.0445
Onchocerca volvulus 0.0156 0.1418 0.2462
Plasmodium vivax plasmepsin V, putative 0.0189 0.1787 0.5094
Onchocerca volvulus Dual oxidase homolog 0.0419 0.4344 0.7543
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.229 0.2426
Schistosoma mansoni cpg binding protein 0.003 0.0018 0.0018
Schistosoma mansoni ap endonuclease 0.0058 0.0328 0.0328
Brugia malayi hypothetical protein 0.0038 0.0104 0.011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0869 0.936 0.9368
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0192 0.0446
Mycobacterium tuberculosis Conserved protein 0.0072 0.0481 0.0927
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0049 0.0231 0.0224
Giardia lamblia Cathepsin L precursor 0.0083 0.0605 0.1733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Brugia malayi Cadherin domain containing protein 0.0049 0.0224 0.0238
Trypanosoma brucei hypothetical protein 0.0099 0.0786 0.1718
Toxoplasma gondii ABC1 family protein 0.0072 0.0481 0.1357
Trypanosoma brucei calpain-like protein, putative 0.0331 0.3362 0.7398
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Entamoeba histolytica calmodulin, putative 0.0049 0.0231 0.0558
Brugia malayi Ets-domain containing protein 0.0074 0.0506 0.0536
Schistosoma mansoni notch 0.0049 0.0224 0.0224
Echinococcus multilocularis peroxidasin 0.0419 0.4344 0.434
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0865 0.0866
Loa Loa (eye worm) programmed cell death protein 6 0.005 0.0238 0.0253
Trypanosoma brucei metacaspase MCA3 0.0123 0.1045 0.2289
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1045 0.1984
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0156 0.1418 0.1411
Schistosoma mansoni slit 0.0049 0.0224 0.0224
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0104 0.011
Schistosoma mansoni survival motor neuron protein 0.0097 0.0761 0.0762
Brugia malayi Kinesin motor domain containing protein 0.0032 0.0037 0.004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0717 0.0759
Echinococcus multilocularis survival motor neuron protein 1 0.0476 0.4983 0.4979
Plasmodium falciparum plasmepsin X 0.0323 0.3278 0.9363
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0083 0.0605 0.164
Giardia lamblia Cathepsin L precursor 0.0083 0.0605 0.1733
Brugia malayi Cathepsin L-like precursor 0.0343 0.35 0.3707
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0111 0.0914 0.1725
Brugia malayi hypothetical protein 0.0476 0.4983 0.5278
Plasmodium falciparum plasmepsin VI 0.0111 0.0914 0.2597
Loa Loa (eye worm) transcriptional regulator 0.0126 0.108 0.1144
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0192 0.1167
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0926 0.9992 1
Echinococcus granulosus cathepsin L 0.0188 0.1779 0.1773
Echinococcus multilocularis protein jagged 1 0.0049 0.0224 0.0217
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.037 0.037
Echinococcus multilocularis hypothetical protein 0.0331 0.3362 0.3357
Loa Loa (eye worm) kinesin-like protein KLP2 0.0032 0.0037 0.004
Leishmania major cathepsin L-like protease 0.0343 0.35 0.7692
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0104 0.0104
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0481 0.051
Echinococcus multilocularis slit 2 protein 0.0049 0.0224 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0104 0.0104
Onchocerca volvulus Cathepsin L homolog 0.0083 0.0605 0.1051
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0123 0.1045 0.1107
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0343 0.35 1
Plasmodium falciparum serine repeat antigen 9 0.0083 0.0605 0.1712
Onchocerca volvulus 0.0343 0.35 0.6078
Loa Loa (eye worm) hypothetical protein 0.0049 0.0231 0.0244
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.1229 0.2347
Plasmodium vivax proteasome subunit beta type-5, putative 0.0155 0.1402 0.3994
Toxoplasma gondii exonuclease III APE 0.0058 0.0328 0.0918
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0328 0.0918
Loa Loa (eye worm) hypothetical protein 0.0118 0.0998 0.1057
Entamoeba histolytica calcium binding family protein 0.0049 0.0231 0.0558
Echinococcus granulosus integrin alpha ps 0.0068 0.0432 0.0425
Brugia malayi Integrin beta pat-3 precursor 0.0309 0.3119 0.3304
Loa Loa (eye worm) integrin beta-2 0.0309 0.3119 0.3304
Loa Loa (eye worm) hypothetical protein 0.0126 0.1083 0.1147
Leishmania major calmodulin-like protein 0.0049 0.0231 0.0445
Brugia malayi Animal haem peroxidase family protein 0.0419 0.4344 0.4601
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0351 0.231
Loa Loa (eye worm) hypothetical protein 0.0038 0.0104 0.011
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0104 0.0096
Plasmodium falciparum proteasome subunit beta type-5 0.0155 0.1402 0.3994
Plasmodium falciparum plasmepsin III 0.0075 0.0513 0.1447
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0123 0.1045 0.1046
Brugia malayi carbohydrate phosphorylase 0.0106 0.0865 0.0916
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0605 0.0641
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0139 0.1229 0.3639
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0481 0.0871
Leishmania major calpain protease-like protein 0.0099 0.0786 0.1677
Giardia lamblia Cathepsin L precursor 0.0083 0.0605 0.1733
Schistosoma mansoni laminin gamma-3 chain 0.0049 0.0224 0.0224
Plasmodium vivax serine-repeat antigen (SERA) 0.0083 0.0605 0.1712
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.004 0.0042
Schistosoma mansoni hypothetical protein 0.0068 0.0434 0.0435
Trypanosoma brucei caltractin, putative 0.0049 0.0231 0.0493
Brugia malayi beta-lactamase family protein 0.0072 0.0481 0.051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0104 0.011
Trichomonas vaginalis myosin light chain 1, putative 0.0049 0.0231 0.0377
Loa Loa (eye worm) beta-lactamase 0.0072 0.0481 0.051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.3571
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.1779 0.5029
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0605 0.1116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Brugia malayi Importin beta-1 subunit 0.0029 0.0007 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0104 0.0096
Plasmodium falciparum serine repeat antigen 1 0.0083 0.0605 0.1712
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0049 0.0224 0.0389
Echinococcus granulosus enteropeptidase 0.0156 0.1418 0.1411
Onchocerca volvulus Cell death protein 3 homolog 0.0244 0.2402 0.4171
Trypanosoma brucei calpain, putative 0.0099 0.0786 0.1718
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0605 0.1116
Onchocerca volvulus 0.0099 0.0785 0.1363
Echinococcus multilocularis neurogenic locus notch protein 0.0049 0.0224 0.0217
Onchocerca volvulus 0.0075 0.0513 0.0891
Plasmodium falciparum serine repeat antigen 6 0.0083 0.0605 0.1712
Loa Loa (eye worm) hypothetical protein 0.0083 0.0605 0.0641
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0238 0.2327 0.4512
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0343 0.35 0.3495
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0104 0.0096
Plasmodium vivax serine-repeat antigen (SERA) 0.0083 0.0605 0.1712
Leishmania major sir2-family protein-like protein 0.0032 0.004 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0099 0.0786 0.0811
Echinococcus granulosus calpain A 0.0331 0.3362 0.3357
Echinococcus multilocularis neurocalcin 0.0049 0.0231 0.0224
Onchocerca volvulus Glycogen phosphorylase homolog 0.0106 0.0865 0.1502
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0045 0.0178 0.0405
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0099 0.0786 0.1718
Toxoplasma gondii preprocathepsin c precursor, putative 0.0083 0.0605 0.1712
Leishmania major cathepsin L-like protease 0.0343 0.35 0.7692
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0481 0.0474
Onchocerca volvulus 0.005 0.0238 0.0414
Loa Loa (eye worm) hypothetical protein 0.0072 0.0481 0.051
Loa Loa (eye worm) glycogen phosphorylase 0.0106 0.0865 0.0916
Plasmodium falciparum serine repeat antigen 7 0.0083 0.0605 0.1712
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0099 0.0786 0.0811
Entamoeba histolytica cysteine proteinase 1, putative 0.0188 0.1779 0.5029
Mycobacterium tuberculosis Conserved protein 0.0072 0.0481 0.0927
Trypanosoma brucei antigen, putative 0.0331 0.3362 0.7398
Trypanosoma brucei metacaspase 0.0123 0.1045 0.2289
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0038 0.0104 0.011
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0446 0.1255
Echinococcus granulosus EF hand domain containing family member A2 0.0049 0.0231 0.0224
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0231 0.0231
Toxoplasma gondii aspartyl protease ASP1 0.0111 0.0914 0.2597
Giardia lamblia Cathepsin B precursor 0.0326 0.3313 1
Schistosoma mansoni gabp alpha 0.0074 0.0506 0.0507
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0083 0.0605 0.1116
Schistosoma mansoni microtubule-associated protein tau 0.0678 0.7233 0.7238
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.004 0.0021
Leishmania major centrin, putative,caltractin, putative 0.0049 0.0231 0.0445
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0385 0.0385
Plasmodium vivax unspecified product 0.0105 0.0853 0.2421
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0099 0.0786 0.1718
Echinococcus granulosus neurogenic locus notch protein 0.0049 0.0224 0.0217
Schistosoma mansoni cathepsin D (A01 family) 0.0492 0.5165 0.5169
Brugia malayi MH2 domain containing protein 0.0234 0.229 0.2426
Loa Loa (eye worm) hypothetical protein 0.0072 0.0481 0.051
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0481 0.0474
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Brugia malayi hypothetical protein 0.0156 0.1418 0.1502
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0328 0.0839
Trypanosoma cruzi cysteine protease, putative 0.0188 0.1779 0.1874
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Trypanosoma cruzi metacaspase, putative 0.0123 0.1045 0.1088
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0083 0.0605 0.0641
Schistosoma mansoni caspase-3 (C14 family) 0.0195 0.185 0.1851
Brugia malayi cathepsin L precursor 0.0083 0.0605 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Brugia malayi Kringle domain containing protein 0.0068 0.0434 0.046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Loa Loa (eye worm) transcriptional regulator 0.0032 0.004 0.0042
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0195 0.185 0.1844
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0351 0.231
Plasmodium vivax unspecified product 0.0188 0.1779 0.5072
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0605 0.0606
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0231 0.0231
Schistosoma mansoni notch 0.0049 0.0224 0.0224
Brugia malayi cathepsin Z-like cysteine proteinase 0.0083 0.0605 0.0641
Echinococcus multilocularis calpain 5 0.0331 0.3362 0.3357
Schistosoma mansoni integrin alpha-ps 0.0035 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.004 0.0006
Echinococcus multilocularis notch 0.0049 0.0224 0.0217
Echinococcus granulosus cysteine protease 0.0188 0.1779 0.1773
Plasmodium vivax aspartyl protease, putative 0.0323 0.3278 0.9363
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0188 0.1779 0.178
Plasmodium vivax hypothetical protein, conserved 0.0032 0.004 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.1779 0.5029
Echinococcus granulosus snurportin 1 0.0314 0.318 0.3175
Plasmodium vivax metacaspase 1, putative 0.0123 0.1045 0.2971
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0104 0.011
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.4344 0.4601
Trypanosoma cruzi major cysteine proteinase, putative 0.0083 0.0605 0.0617
Plasmodium vivax vivapain-3 0.0188 0.1779 0.5072
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.004 0.0032
Entamoeba histolytica grainin 2 0.0049 0.0231 0.0558
Onchocerca volvulus 0.0068 0.0434 0.0754
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Onchocerca volvulus 0.0343 0.35 0.6078
Schistosoma mansoni hypothetical protein 0.0097 0.0761 0.0762
Schistosoma mansoni hypothetical protein 0.0049 0.0231 0.0231
Onchocerca volvulus Slit protein homolog 0.0049 0.0224 0.0389
Loa Loa (eye worm) hypothetical protein 0.0777 0.8334 0.8827
Trichomonas vaginalis set domain proteins, putative 0.0487 0.5109 1
Brugia malayi Trypsin family protein 0.0156 0.1418 0.1502
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0052 0.0261 0.1664
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.004 0.0006
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0351 0.0653
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0446 0.1255
Plasmodium vivax aspartyl protease, putative 0.0075 0.0513 0.1447
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0326 0.3313 0.3316
Leishmania major kinesin, putative 0.0231 0.2255 0.4931
Brugia malayi cathepsin L-like cysteine proteinase 0.0083 0.0605 0.0641
Entamoeba histolytica hypothetical protein 0.0038 0.0104 0.0191
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Brugia malayi Cytochrome P450 family protein 0.0052 0.0258 0.0274
Schistosoma mansoni integrin alpha-ps 0.0068 0.0432 0.0433
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0446 0.0446
Onchocerca volvulus 0.0097 0.0761 0.1322
Brugia malayi PXA domain containing protein 0.0038 0.0104 0.011
Echinococcus granulosus Glycosyl transferase family 35 0.0106 0.0865 0.0858
Echinococcus multilocularis calmodulin 0.0049 0.0231 0.0224
Echinococcus granulosus calumenin 0.005 0.0238 0.0231
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Onchocerca volvulus 0.0072 0.0481 0.0836
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0049 0.0231 0.0558
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0075 0.0513 0.0543
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0605 0.1116
Loa Loa (eye worm) hypothetical protein 0.0869 0.936 0.9915
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0049 0.0231 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1045 0.1984
Brugia malayi calcium-binding protein 0.0049 0.0231 0.0244
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Schistosoma mansoni centrin-related 0.0049 0.0231 0.0231
Entamoeba histolytica cysteine proteinase 2 0.0188 0.1779 0.5029
Loa Loa (eye worm) cysteine protease 0.0343 0.35 0.3707
Leishmania major protein kinase, putative 0.0049 0.0231 0.0445
Schistosoma mansoni chromatin regulatory protein sir2 0.0126 0.108 0.1081
Echinococcus multilocularis tissue type plasminogen activator 0.0068 0.0434 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.004 0.001
Loa Loa (eye worm) proteasome subunit beta type 2 0.0045 0.0178 0.0188
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Toxoplasma gondii EGF family domain-containing protein 0.0049 0.0224 0.0621
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0481 0.051
Leishmania major hypothetical protein, conserved 0.0072 0.0481 0.1
Leishmania major calpain family cysteine protease-like protein 0.0099 0.0786 0.1677
Schistosoma mansoni rab 0.0049 0.0231 0.0231
Plasmodium falciparum serine repeat antigen 4 0.0083 0.0605 0.1712
Giardia lamblia Cysteine protease 0.0083 0.0605 0.1733
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0083 0.0605 0.1712
Schistosoma mansoni integrin alpha 0.0151 0.1359 0.136
Trypanosoma cruzi major cysteine proteinase, putative 0.0177 0.1647 0.1733
Echinococcus granulosus proteasome prosome macropain 0.0155 0.1402 0.1396
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.4451 0.4714
Onchocerca volvulus 0.0546 0.5759 1
Leishmania major cathepsin L-like protease 0.0343 0.35 0.7692
Trichomonas vaginalis calmodulin, putative 0.005 0.0238 0.0392
Loa Loa (eye worm) hypothetical protein 0.0105 0.0853 0.0903
Trypanosoma cruzi I/6 autoantigen, putative 0.0049 0.0231 0.0215
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.004 0.0032
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0156 0.1418 0.1419
Echinococcus granulosus centrin 2 0.0049 0.0231 0.0224
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0104 0.0126
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0343 0.35 0.3707
Echinococcus granulosus EF HAND 1 calcium binding site 0.0049 0.0231 0.0224
Brugia malayi Trypsin-like protease protein 5 0.0156 0.1418 0.1502
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0126 0.108 0.3011
Echinococcus multilocularis caspase 8 0.0123 0.1045 0.1039
Echinococcus multilocularis fat cadherin tumor suppressor 0.0049 0.0224 0.0217
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.3571
Echinococcus granulosus expressed protein 0.0742 0.7941 0.7939
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0331 0.3362 0.7398
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0869 0.936 0.9368
Schistosoma mansoni calpain (C02 family) 0.0331 0.3362 0.3364
Plasmodium vivax SET domain protein, putative 0.0062 0.037 0.1038
Echinococcus multilocularis beta adrenergic receptor kinase 0.0038 0.0104 0.0096
Loa Loa (eye worm) hypothetical protein 0.0062 0.037 0.0392
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0717 0.0717
Toxoplasma gondii cathepsin CPC1 0.0083 0.0605 0.1712
Brugia malayi Calcium binding EGF domain containing protein 0.0049 0.0224 0.0238
Brugia malayi Ets-domain containing protein 0.0074 0.0506 0.0536
Onchocerca volvulus 0.0343 0.35 0.6078
Trypanosoma cruzi cysteine peptidase, putative 0.0188 0.1779 0.1874
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0258 0.0274
Trypanosoma brucei calpain-like protein, putative 0.0331 0.3362 0.7398
Leishmania major proteasome beta 5 subunit, putative 0.0155 0.1402 0.3042
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0446 0.0921
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0865 0.0858
Schistosoma mansoni memapsin-2 (A01 family) 0.049 0.5136 0.514
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0049 0.0231 0.0215
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0083 0.0605 0.1733
Onchocerca volvulus 0.0156 0.1418 0.2462
Schistosoma mansoni calmodulin related calcium binding protein 0.0049 0.0231 0.0231
Onchocerca volvulus 0.0488 0.5111 0.8876
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0481 0.0871
Brugia malayi Pre-SET motif family protein 0.0062 0.037 0.0392
Brugia malayi calpain 7 0.0331 0.3362 0.3561
Brugia malayi Cathepsin L-like precursor 0.0343 0.35 0.3707
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0328 0.0569
Loa Loa (eye worm) calpain D 0.0099 0.0786 0.0833
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.037 0.0363
Loa Loa (eye worm) hypothetical protein 0.0083 0.0605 0.0641
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.3571
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Echinococcus multilocularis cathepsin L 0.0188 0.1779 0.1773
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.1229 0.2347
Echinococcus multilocularis neurogenic locus protein delta 0.0049 0.0224 0.0217
Echinococcus multilocularis proteasome (prosome, macropain) 0.0155 0.1402 0.1396
Echinococcus granulosus cathepsin l1 0.0343 0.35 0.3495
Trypanosoma cruzi metacaspase, putative 0.0123 0.1045 0.1088
Brugia malayi GCC2 and GCC3 family protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) hypothetical protein 0.0105 0.0853 0.0903
Schistosoma mansoni hypothetical protein 0.0215 0.2078 0.208
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0126 0.108 0.2053
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0104 0.0126
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0126 0.108 0.3011
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1045 0.1984
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.1779 0.3907
Entamoeba histolytica calpain family cysteine protease, putative 0.0099 0.0786 0.2163
Trichomonas vaginalis calmodulin-2, putative 0.0049 0.0231 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Brugia malayi calpain 5 0.0099 0.0786 0.0833
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0083 0.0605 0.1712
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0605 0.1116
Loa Loa (eye worm) hypothetical protein 0.0139 0.1229 0.1302
Entamoeba histolytica cysteine protease, putative 0.0083 0.0605 0.164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Loa Loa (eye worm) hypothetical protein 0.0343 0.35 0.3707
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0038 0.0104 0.011
Echinococcus granulosus calmodulin 0.0049 0.0231 0.0224
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0099 0.0786 0.223
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0099 0.0786 0.1473
Loa Loa (eye worm) transcriptional regulator 0.0032 0.004 0.0042
Brugia malayi Angiotensin-converting enzyme family protein 0.0611 0.6489 0.6873
Trichomonas vaginalis calcineurin B subunit, putative 0.005 0.0238 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0099 0.0786 0.0811
Echinococcus granulosus cathepsin L cysteine proteinase 0.0343 0.35 0.3495
Toxoplasma gondii cathepsin CPC2 0.0083 0.0605 0.1712
Echinococcus granulosus cathepsin L 0.0083 0.0605 0.0598
Leishmania major calmodulin-like protein 0.0049 0.0231 0.0445
Schistosoma mansoni reticulocalbin 0.005 0.0238 0.0239
Onchocerca volvulus Peroxidase homolog 0.0419 0.4344 0.7543
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Brugia malayi cathepsin B-like cysteine proteinase 0.0869 0.936 0.9915
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0068 0.0434 0.1222
Echinococcus granulosus calpain 0.0331 0.3362 0.3357
Brugia malayi RNA, U transporter 1 0.0084 0.0612 0.0648
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0605 0.0641
Echinococcus granulosus prolyl endopeptidase 0.0131 0.1142 0.1135
Giardia lamblia Cathepsin B precursor 0.0083 0.0605 0.1733
Plasmodium falciparum centrin-1 0.0049 0.0231 0.0639
Trypanosoma brucei oligopeptidase b 0.0052 0.0261 0.0559
Trypanosoma brucei centrin, putative 0.0049 0.0231 0.0493
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0328 0.0321
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0083 0.0605 0.0606
Onchocerca volvulus 0.0072 0.0481 0.0836
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Onchocerca volvulus 0.0343 0.35 0.6078
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0045 0.0178 0.0158
Plasmodium vivax hypothetical protein, conserved 0.0123 0.1045 0.2971
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.4344 0.4601
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0083 0.0605 0.1712
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0083 0.0605 0.1712
Trichomonas vaginalis calpain, putative 0.0099 0.0786 0.1473
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0104 0.0104
Echinococcus multilocularis Glycosyl transferase, family 35 0.0106 0.0865 0.0858
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0481 0.0482
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1718
Schistosoma mansoni chromatin regulatory protein sir2 0.0139 0.1229 0.123
Echinococcus granulosus neurogenic locus notch protein 0.0049 0.0224 0.0217
Loa Loa (eye worm) CYP4Cod1 0.0031 0.003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0481 0.0927
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0231 0.0377
Trichomonas vaginalis calcium binding proteins, putative 0.0049 0.0231 0.0377
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0446 0.0446
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0611 0.6489 0.6873
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0328 0.0347
Echinococcus multilocularis calbindin 32 0.005 0.0238 0.0231
Loa Loa (eye worm) hypothetical protein 0.0072 0.0481 0.051
Loa Loa (eye worm) hypothetical protein 0.0876 0.9441 1
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0045 0.0178 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0343 0.35 0.6827
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0083 0.0605 0.0606
Schistosoma mansoni calpain C (C02 family) 0.0331 0.3362 0.3364
Loa Loa (eye worm) hypothetical protein 0.0114 0.095 0.1006
Trypanosoma cruzi 20S proteasome subunit 0.0045 0.0178 0.0158
Brugia malayi Cathepsin L-like precursor 0.0343 0.35 0.3707
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Echinococcus granulosus microtubule associated protein 2 0.0678 0.7233 0.7231
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0446 0.0439
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0131 0.1142 0.1142
Echinococcus multilocularis cysteine protease 0.0343 0.35 0.3495
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.005 0.0238 0.0223
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0083 0.0605 0.1712
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0192 0.0446
Toxoplasma gondii cathepsin CPL 0.0343 0.35 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0326 0.3313 0.7291
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.037 0.037
Schistosoma mansoni importin beta-1 0.0029 0.0007 0.0007
Plasmodium vivax hypothetical protein, conserved 0.005 0.0238 0.0662
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0104 0.0096
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.037 0.1038
Onchocerca volvulus 0.0049 0.0224 0.0389
Onchocerca volvulus Putative cubilin 0.0049 0.0224 0.0389
Schistosoma mansoni calpain-2 (C02 family) 0.0099 0.0786 0.0787
Brugia malayi cathepsin F-like cysteine proteinase 0.0083 0.0605 0.0641
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0155 0.1402 0.1485
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0083 0.0605 0.1712
Echinococcus granulosus cathepsin L cysteine protease 0.0188 0.1779 0.1773
Loa Loa (eye worm) hypothetical protein 0.0038 0.0104 0.011
Loa Loa (eye worm) hypothetical protein 0.0099 0.0786 0.0833
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0045 0.0178 0.0376
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0083 0.0605 0.1712
Trypanosoma cruzi calmodulin, putative 0.0049 0.0231 0.0215
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0865 0.239
Trypanosoma brucei calpain-like protein, putative 0.0331 0.3362 0.7398
Onchocerca volvulus 0.0343 0.35 0.6078
Loa Loa (eye worm) hypothetical protein 0.0238 0.2327 0.2464
Trypanosoma brucei Calpain-like protein 1.1 0.0099 0.0786 0.1718
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0104 0.011
Plasmodium vivax calpain, putative 0.0331 0.3362 0.9603
Leishmania major i/6 autoantigen-like protein 0.0049 0.0231 0.0445
Trichomonas vaginalis esterase, putative 0.0072 0.0481 0.0871
Schistosoma mansoni caspase-7 (C14 family) 0.0195 0.185 0.1851
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0605 0.1116
Echinococcus granulosus kinesin family 1 0.0247 0.2436 0.2431
Brugia malayi programmed cell death protein 6 0.0049 0.0231 0.0244
Brugia malayi Eukaryotic aspartyl protease family protein 0.0075 0.0513 0.0543
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.3362 0.3571
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Brugia malayi proteasome subunit beta type 1 0.0069 0.0446 0.0472
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0786 0.1473
Leishmania major hypothetical protein, conserved 0.0068 0.0434 0.0896
Echinococcus granulosus protein jagged 1 0.0049 0.0224 0.0217
Brugia malayi hypothetical protein 0.0075 0.0513 0.0543
Schistosoma mansoni ap endonuclease 0.0058 0.0328 0.0328
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0104 0.0104
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0178 0.0178
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0481 0.0482
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.1045 0.1984
Loa Loa (eye worm) hypothetical protein 0.0075 0.0513 0.0543
Brugia malayi Muscle positioning protein 4 0.0049 0.0224 0.0238
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0104 0.0096
Echinococcus multilocularis programmed cell death protein 0.0049 0.0231 0.0224
Echinococcus multilocularis chromatin regulatory protein sir2 0.0126 0.108 0.1074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0328 0.0707
Loa Loa (eye worm) hypothetical protein 0.0546 0.5759 0.61
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Loa Loa (eye worm) hypothetical protein 0.0122 0.1036 0.1098
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0869 0.936 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Trypanosoma cruzi centrin, putative 0.0049 0.0231 0.0215
Onchocerca volvulus Neurogenic locus notch homolog 0.0049 0.0227 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0104 0.0126
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0104 0.011
Entamoeba histolytica hypothetical protein 0.0083 0.0605 0.164
Onchocerca volvulus 0.0072 0.0481 0.0836
Echinococcus multilocularis tumor protein p63 0.0678 0.7233 0.7231
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0155 0.1402 0.2689
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0049 0.0231 0.0231
Loa Loa (eye worm) calpain family protein 1 0.0876 0.9441 1
Plasmodium vivax proteasome subunit beta type-2, putative 0.0045 0.0178 0.0488
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.3362 0.3571
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Schistosoma mansoni centrin 0.0049 0.0231 0.0231
Brugia malayi notch-like transmembrane receptor 0.0049 0.0224 0.0238
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0192 0.032
Chlamydia trachomatis glycogen phosphorylase 0.0106 0.0865 0.5
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0865 0.0858
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0351 0.0351
Schistosoma mansoni hypothetical protein 0.0156 0.1418 0.1419
Brugia malayi Cathepsin L-like precursor 0.0343 0.35 0.3707
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0328 0.2148
Schistosoma mansoni cathepsin F (C01 family) 0.0343 0.35 0.3503
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0605 0.0641
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0047 0.0202 0.0214
Loa Loa (eye worm) notch protein 0.0049 0.0224 0.0238
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0343 0.35 0.3495
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0926 0.9992 0.9992
Onchocerca volvulus Huntingtin homolog 0.0126 0.1083 0.1881
Loa Loa (eye worm) hypothetical protein 0.0123 0.1045 0.1107
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0131 0.1142 0.2464
Leishmania major programmed cell death 6 protein-like protein 0.0049 0.0231 0.0445
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0761 0.0806
Loa Loa (eye worm) hypothetical protein 0.0035 0.0071 0.0076
Brugia malayi beta-lactamase family protein 0.0072 0.0481 0.051
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0178 0.0178
Echinococcus granulosus caspase 2 0.0244 0.2402 0.2397
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0155 0.1402 0.1404
Plasmodium falciparum calpain 0.0099 0.0786 0.223
Toxoplasma gondii prolyl endopeptidase 0.0131 0.1142 0.3247
Trypanosoma brucei centrin-3 0.0049 0.0231 0.0493
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.7398
Plasmodium falciparum serine repeat antigen 5 0.0083 0.0605 0.1712
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0605 0.0606
Giardia lamblia Cathepsin B precursor 0.0326 0.3313 1
Onchocerca volvulus Cathepsin L homolog 0.0343 0.35 0.6078
Echinococcus multilocularis cpg binding protein 0.003 0.0018 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0717 0.071
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0481 0.0484
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.4344 0.4601
Trypanosoma cruzi calmodulin, putative 0.0049 0.0231 0.0215
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0052 0.0261 0.0465
Entamoeba histolytica cysteine proteinase, putative 0.0343 0.35 1
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0156 0.1418 0.1411
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Loa Loa (eye worm) ctsf protein 0.0343 0.35 0.3707
Entamoeba histolytica calcium-binding protein, putative 0.0049 0.0231 0.0558
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0351 0.0351
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0328 0.032
Leishmania major calmodulin, putative 0.0049 0.0231 0.0445
Brugia malayi Blistered cuticle protein 3 0.0419 0.4344 0.4601
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0111 0.0914 0.0968
Giardia lamblia Cathepsin B precursor 0.0083 0.0605 0.1733
Trypanosoma cruzi cruzipain precursor, putative 0.0105 0.0853 0.0882
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Brugia malayi prolyl oligopeptidase family protein 0.0131 0.1142 0.1209
Plasmodium vivax aspartyl proteinase, putative 0.0111 0.0914 0.2597
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0049 0.0231 0.0639
Schistosoma mansoni hypothetical protein 0.0156 0.1418 0.1419
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0099 0.0786 0.0811
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.004 0.0092
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0717 0.071
Trypanosoma cruzi centrin-3 0.0049 0.0231 0.0215
Loa Loa (eye worm) aspartyl protease 6 0.0075 0.0513 0.0543
Brugia malayi hypothetical protein 0.0122 0.1036 0.1098
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.004 0.0071
Onchocerca volvulus 0.0156 0.1418 0.2462
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Echinococcus multilocularis microtubule associated protein 2 0.0678 0.7233 0.7231
Entamoeba histolytica cysteine protease, putative 0.0083 0.0605 0.164
Trypanosoma cruzi cysteine peptidase, putative 0.0436 0.4542 0.4835
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Echinococcus granulosus neurogenic locus protein delta 0.0049 0.0224 0.0217
Trichomonas vaginalis calpain, putative 0.0099 0.0786 0.1473
Onchocerca volvulus 0.0049 0.0224 0.0389
Leishmania major hypothetical protein, conserved 0.005 0.0238 0.0462
Echinococcus multilocularis neurogenic locus notch protein 4 0.0049 0.0224 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0605 0.1116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0104 0.0096
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0481 0.1931
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0043
Entamoeba histolytica hypothetical protein, conserved 0.005 0.0238 0.058
Toxoplasma gondii proteasome subunit beta type, putative 0.0155 0.1402 0.3994
Plasmodium falciparum plasmepsin V 0.0189 0.1787 0.5094
Trypanosoma cruzi I/6 autoantigen, putative 0.0049 0.0231 0.0215
Loa Loa (eye worm) hypothetical protein 0.0111 0.0914 0.0968
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0083 0.0605 0.1733
Brugia malayi aspartic protease BmAsp-2, identical 0.0075 0.0513 0.0543
Trypanosoma brucei Calpain-like protein 1.2 0.0099 0.0786 0.1718
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0049 0.0231 0.0215
Trypanosoma brucei Metacaspase-4 0.0123 0.1045 0.2289
Leishmania major phospholipase c-like protein 0.0049 0.0231 0.0445
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0083 0.0605 0.0641
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0104 0.0104
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0328 0.032
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0049 0.0224 0.0238
Toxoplasma gondii calmodulin CAM1 0.005 0.0238 0.0662
Echinococcus granulosus slit 2 protein 0.0049 0.0224 0.0217
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0328 0.5
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Echinococcus granulosus notch 0.0049 0.0224 0.0217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0717 0.0717
Echinococcus multilocularis neurogenic locus notch protein 0.0049 0.0224 0.0217
Brugia malayi Papain family cysteine protease containing protein 0.0343 0.35 0.3707
Schistosoma mansoni cathepsin D (A01 family) 0.0492 0.5165 0.5169
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0155 0.1402 0.1471
Giardia lamblia Cysteine protease 0.0083 0.0605 0.1733
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0343 0.35 0.3707
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Trypanosoma brucei protein I/6 0.0049 0.0231 0.0493
Loa Loa (eye worm) trypsin family protein 0.0156 0.1418 0.1502
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Schistosoma mansoni ef hand domain family member A2 0.0049 0.0231 0.0231
Loa Loa (eye worm) Notch2 0.0049 0.0224 0.0238
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0045 0.0178 0.017
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0865 0.1628
Plasmodium falciparum plasmepsin VIII, putative 0.0075 0.0513 0.1447
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0155 0.1402 0.3077
Echinococcus granulosus programmed cell death protein 0.0049 0.0231 0.0224
Echinococcus multilocularis cysteine protease 0.0343 0.35 0.3495
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0104 0.011
Plasmodium falciparum kinesin-5 0.0032 0.0037 0.0086
Entamoeba histolytica cysteine protease, putative 0.0343 0.35 1
Echinococcus granulosus cathepsin b 0.0869 0.936 0.936
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.7385
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Entamoeba histolytica cysteine protease, putative 0.0083 0.0605 0.164
Trypanosoma cruzi oligopeptidase b 0.0052 0.0261 0.0247
Schistosoma mansoni calmodulin 0.0049 0.0231 0.0231
Giardia lamblia Cathepsin B precursor 0.0083 0.0605 0.1733
Brugia malayi Cytochrome P450 family protein 0.0031 0.003 0.0032
Echinococcus multilocularis neuronal calcium sensor 0.0049 0.0231 0.0224
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0083 0.0605 0.1712
Onchocerca volvulus 0.0049 0.0224 0.0389
Toxoplasma gondii aspartyl protease ASP5 0.0114 0.0953 0.2708
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0083 0.0605 0.0641
Echinococcus multilocularis cathepsin L cysteine protease 0.0343 0.35 0.3495
Schistosoma mansoni calpain-7 (C02 family) 0.0334 0.3396 0.3398
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0123 0.1045 0.2971
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Echinococcus granulosus neurogenic locus notch protein 4 0.0049 0.0224 0.0217
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.004 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Schistosoma mansoni calpain-7 (C02 family) 0.0334 0.3396 0.3398
Leishmania major cathepsin L-like protease 0.0436 0.4542 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0049 0.0231 0.0215
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0178 0.0272
Brugia malayi Fli-1 protein 0.0225 0.219 0.232
Giardia lamblia Glycogen phosphorylase 0.0106 0.0865 0.2526
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0328 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.1779 0.3431
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0104 0.011
Schistosoma mansoni Mername-AA248 (C02 family) 0.0331 0.3362 0.3364
Leishmania major centrin, putative 0.0049 0.0231 0.0445
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0717 0.0717
Trypanosoma brucei prolyl oligopeptidase, putative 0.0052 0.0261 0.0559
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0083 0.0605 0.1712
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0343 0.35 0.6827
Trypanosoma cruzi cysteine peptidase, putative 0.0436 0.4542 0.4835
Onchocerca volvulus Peroxidase homolog 0.0419 0.4344 0.7543
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) animal heme peroxidase 0.0419 0.4344 0.4601
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0083 0.0605 0.0641
Echinococcus multilocularis cathepsin b 0.0869 0.936 0.936
Giardia lamblia Cysteine protease 0.0083 0.0605 0.1733
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Trichomonas vaginalis centrin, putative 0.0049 0.0231 0.0377
Loa Loa (eye worm) hypothetical protein 0.0083 0.0605 0.0641
Echinococcus granulosus apoptotic protease activating factor 1 0.0122 0.1036 0.103
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0105 0.0853 0.0903
Schistosoma mansoni hypothetical protein 0.0099 0.0786 0.0787
Echinococcus granulosus Mastin 0.0156 0.1418 0.1411
Brugia malayi Cathepsin L-like precursor 0.0343 0.35 0.3707
Plasmodium falciparum serine repeat antigen 8 0.0083 0.0605 0.1712
Onchocerca volvulus 0.0419 0.4344 0.7543
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0328 0.0918
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0104 0.0096
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0104 0.0096
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0139 0.1229 0.1223
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0192 0.0192
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0104 0.0096
Loa Loa (eye worm) fli-1 protein 0.0225 0.219 0.232
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.003 0.0032
Echinococcus granulosus chromatin regulatory protein sir2 0.0126 0.108 0.1074
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0083 0.0605 0.0606
Onchocerca volvulus 0.0049 0.0224 0.0389
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0099 0.0786 0.1718
Entamoeba histolytica protein kinase, putative 0.0231 0.2255 0.6403
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0446 0.0801
Echinococcus granulosus integrin alpha ps 0.0032 0.004 0.0033
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0075 0.0513 0.1447
Schistosoma mansoni cathepsin S (C01 family) 0.0083 0.0605 0.0606
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.229 0.2426
Echinococcus multilocularis prolyl endopeptidase 0.0131 0.1142 0.1135
Loa Loa (eye worm) hypothetical protein 0.0083 0.0605 0.0641
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0083 0.0605 0.1712
Loa Loa (eye worm) blistered cuticle protein 3 0.0419 0.4344 0.4601
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) hypothetical protein 0.0047 0.0202 0.0214
Brugia malayi calpain D 0.0099 0.0786 0.0833
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0481 0.0927
Echinococcus multilocularis enteropeptidase 0.0156 0.1418 0.1411
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0231 0.0231
Trypanosoma cruzi cysteine proteinase, putative 0.0188 0.1779 0.1874
Toxoplasma gondii calcium-dependent protein kinase 0.005 0.0238 0.0662
Brugia malayi PXA domain containing protein 0.0038 0.0104 0.011
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0865 0.0866
Giardia lamblia Cathepsin B precursor 0.0326 0.3313 1
Echinococcus multilocularis cathepsin L 0.0083 0.0605 0.0598
Leishmania major cysteine peptidase A (CPA) 0.0343 0.35 0.7692
Schistosoma mansoni hypothetical protein 0.0032 0.004 0.004
Brugia malayi Proteasome A-type and B-type family protein 0.0155 0.1402 0.1485
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Mycobacterium leprae Probable lipase LipE 0.0072 0.0481 0.1931
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0123 0.1045 0.2971
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0049 0.0231 0.0215
Loa Loa (eye worm) hypothetical protein 0.0107 0.0869 0.0921
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0099 0.0786 0.0811
Loa Loa (eye worm) hypothetical protein 0.0075 0.0513 0.0543
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0111 0.0914 0.0915
Entamoeba histolytica cysteine proteinase, putative 0.0343 0.35 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0038 0.0104 0.0096
Brugia malayi Cathepsin L-like precursor 0.0238 0.2327 0.2464
Brugia malayi Cytochrome P450 family protein 0.0031 0.003 0.0032
Plasmodium falciparum metacaspase-like protein 0.0123 0.1045 0.2971
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0446 0.0967
Trichomonas vaginalis calcium binding protein, putative 0.0049 0.0231 0.0377
Brugia malayi Cell death protein 3 precursor 0.0244 0.2402 0.2544
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0104 0.0104
Onchocerca volvulus 0.0343 0.35 0.6078
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0155 0.1402 0.1471
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni cpg binding protein 0.003 0.0018 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.1779 0.5029
Echinococcus multilocularis calmodulin 0.0049 0.0231 0.0224
Onchocerca volvulus 0.0152 0.137 0.2379
Loa Loa (eye worm) calpain 5 0.0231 0.2255 0.2388
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0351 0.0711
Echinococcus multilocularis protein jagged 1 0.0049 0.0224 0.0217
Brugia malayi Trypsin family protein 0.0156 0.1418 0.1502
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Brugia malayi Cathepsin L-like cysteine proteinase 0.0238 0.2327 0.2464
Echinococcus multilocularis calumenin 0.005 0.0238 0.0231
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0351 0.0983
Giardia lamblia Cathepsin B precursor 0.0083 0.0605 0.1733
Mycobacterium ulcerans hypothetical protein 0.0072 0.0481 0.3253
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Plasmodium falciparum metacaspase 1 0.0123 0.1045 0.2971
Onchocerca volvulus 0.0062 0.037 0.0642
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0481 0.3253
Plasmodium falciparum plasmepsin IV 0.0111 0.0914 0.2597
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0155 0.1402 1
Echinococcus granulosus neuronal calcium sensor 0.0049 0.0231 0.0224
Onchocerca volvulus Cathepsin L homolog 0.0343 0.35 0.6078
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0126 0.108 0.1126
Trypanosoma brucei centrin, putative 0.0049 0.0231 0.0493
Loa Loa (eye worm) hypothetical protein 0.0238 0.2327 0.2464
Echinococcus multilocularis programmed cell death protein 0.0049 0.0231 0.0224
Plasmodium vivax centrin-1, putative 0.0049 0.0231 0.0639
Leishmania major cathepsin L-like protease 0.0343 0.35 0.7692
Plasmodium falciparum plasmepsin VII 0.0075 0.0513 0.1447
Giardia lamblia Cathepsin L precursor 0.0083 0.0605 0.1733
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0111 0.0914 0.0908
Trypanosoma brucei calmodulin, putative 0.005 0.0238 0.051
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0083 0.0605 0.0641
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0139 0.1229 0.1223
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0083 0.0605 0.1712
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Echinococcus multilocularis EF hand domain containing family member A2 0.005 0.0238 0.0231
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.004 0.0069
Loa Loa (eye worm) hypothetical protein 0.0063 0.0386 0.0409
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0865 0.0858
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0865 0.239
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni hypothetical protein 0.0049 0.0224 0.0224
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0869 0.936 0.9368
Trypanosoma brucei prolyl endopeptidase 0.0131 0.1142 0.2502
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Loa Loa (eye worm) hypothetical protein 0.0072 0.0481 0.051
Loa Loa (eye worm) hypothetical protein 0.0645 0.6866 0.7272
Brugia malayi EF hand family protein 0.0049 0.0231 0.0244
Loa Loa (eye worm) calpain 0.0331 0.3362 0.3561
Entamoeba histolytica cysteine protease, putative 0.0083 0.0605 0.164
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Brugia malayi Calcium binding EGF domain containing protein 0.0049 0.0224 0.0238
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0104 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0605 0.1116
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0099 0.0786 0.0811
Echinococcus granulosus EF hand domain containing family member A2 0.005 0.0238 0.0231
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.037 0.037
Loa Loa (eye worm) hypothetical protein 0.0083 0.0606 0.0642
Trypanosoma cruzi cysteine peptidase, putative 0.0436 0.4542 0.4835
Plasmodium vivax kinesin-5 0.0032 0.0037 0.0086
Echinococcus multilocularis protein jagged 2 0.0049 0.0224 0.0217
Brugia malayi Papain family cysteine protease containing protein 0.0188 0.1779 0.1884
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Plasmodium vivax vivapain-1 0.0188 0.1779 0.5072
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0099 0.0786 0.0811
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0809 0.8686 0.8685
Toxoplasma gondii centrin, putative 0.0049 0.0231 0.0639
Plasmodium falciparum plasmepsin IX 0.0323 0.3278 0.9363
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0114 0.095 0.1006
Echinococcus granulosus neural cadherin 0.0049 0.0224 0.0217
Echinococcus granulosus caspase 8 0.0123 0.1045 0.1039
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0481 0.0927
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Brugia malayi hypothetical protein 0.0152 0.137 0.1451
Mycobacterium tuberculosis Conserved protein 0.0072 0.0481 0.0927
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0188 0.1779 0.1874
Echinococcus granulosus survival motor neuron protein 1 0.0476 0.4983 0.4979
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0123 0.1045 0.1984
Brugia malayi calpain family protein 1 0.0876 0.9441 1
Onchocerca volvulus 0.0049 0.0231 0.0401
Onchocerca volvulus 0.0419 0.4344 0.7543
Giardia lamblia Hypothetical protein 0.0083 0.0605 0.1733
Schistosoma mansoni reticulocalbin 0.0049 0.0231 0.0231
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0049 0.0224 0.0224
Plasmodium vivax aspartyl protease, putative 0.0323 0.3278 0.9363
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0481 0.0927
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0075 0.0513 0.0513
Echinococcus multilocularis caspase 0.0195 0.185 0.1844
Plasmodium falciparum cysteine proteinase falcipain 1 0.0188 0.1779 0.5072
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0717 0.071
Loa Loa (eye worm) hypothetical protein 0.0038 0.0104 0.011
Entamoeba histolytica hypothetical protein 0.0038 0.0104 0.0191
Entamoeba histolytica cysteine proteinase, putative 0.0238 0.2327 0.6611
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1677
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0351 0.0344
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.0853 0.0882
Trypanosoma brucei Calpain-like protein CALP1.3 0.0099 0.0786 0.1718
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.1718
Loa Loa (eye worm) hypothetical protein 0.0099 0.0785 0.0831
Giardia lamblia Encystation-specific protease 0.0083 0.0605 0.1733
Brugia malayi Integrin alpha pat-2 precursor 0.0151 0.1359 0.1439
Brugia malayi cathepsin F-like cysteine proteinase 0.0105 0.0853 0.0903
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0446 0.1246
Entamoeba histolytica cysteine protease, putative 0.0083 0.0605 0.164
Brugia malayi hypothetical protein 0.0075 0.0513 0.0543
Loa Loa (eye worm) hypothetical protein 0.0156 0.1418 0.1502
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0481 0.0871
Giardia lamblia Sirtuin type 2 0.0032 0.004 0.0006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1419
Schistosoma mansoni cercarial elastase (S01 family) 0.0156 0.1418 0.1419
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0351 0.231
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0717 0.0759
Toxoplasma gondii kringle domain-containing protein 0.0068 0.0434 0.1222
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0104 0.0126
Plasmodium falciparum plasmepsin II 0.0111 0.0914 0.2597
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0326 0.3313 0.6457
Echinococcus granulosus caspase 0.0195 0.185 0.1844
Echinococcus granulosus integrin beta 2 0.0229 0.2228 0.2222
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Echinococcus multilocularis expressed protein 0.0742 0.7941 0.7939
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0126 0.108 0.2366
Brugia malayi EGF-like domain containing protein 0.0049 0.0224 0.0238
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0481 0.0927
Plasmodium vivax aspartyl proteinase, putative 0.0075 0.0513 0.1447
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0099 0.0786 0.1473
Loa Loa (eye worm) hypothetical protein 0.0083 0.0605 0.0641
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0104 0.0104
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0104 0.0096
Loa Loa (eye worm) hypothetical protein 0.0083 0.0605 0.0641
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0104 0.011
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.4803 1
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0506 0.05
Brugia malayi cathepsin L-like precursor 0.0238 0.2327 0.2464
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0926 0.9992 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.1229 0.2347
Brugia malayi Pre-SET motif family protein 0.0428 0.4451 0.4714
Echinococcus granulosus caspase 3 0.0072 0.0484 0.0477
Echinococcus multilocularis calpain 0.0331 0.3362 0.3357
Mycobacterium ulcerans beta-lactamase 0.0072 0.0481 0.3253
Plasmodium vivax plasmepsin IV, putative 0.0111 0.0914 0.2597
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0099 0.0786 0.0811
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0083 0.0605 0.1733
Trypanosoma cruzi kinesin, putative 0.0231 0.2255 0.2384
Echinococcus multilocularis integrin alpha ps 0.0032 0.004 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0038 0.0104 0.011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0008
Echinococcus granulosus tissue type plasminogen activator 0.0068 0.0434 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0605 0.1116
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.7385
Schistosoma mansoni cathepsin F (C01 family) 0.0343 0.35 0.3503
Toxoplasma gondii kinesin motor domain-containing protein 0.0032 0.0037 0.0086
Loa Loa (eye worm) cathepsin B 0.0326 0.3313 0.3509
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0126 0.108 0.1074
Schistosoma mansoni peroxidasin 0.0419 0.4344 0.4347
Echinococcus multilocularis dnaJ subfamily B 0.041 0.4246 0.4242
Schistosoma mansoni neuronal calcium sensor 0.0049 0.0231 0.0231
Echinococcus multilocularis cathepsin L cysteine protease 0.0343 0.35 0.3495
Schistosoma mansoni calcium binding atopy-related autoantigen 0.005 0.0238 0.0239
Loa Loa (eye worm) hypothetical protein 0.0419 0.4344 0.4601
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0231 0.0377
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0126 0.108 0.2053
Brugia malayi hypothetical protein 0.0419 0.4344 0.4601
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.004 0.0069
Brugia malayi Papain family cysteine protease containing protein 0.0188 0.1779 0.1884
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0104 0.0104
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0099 0.0786 0.0811
Giardia lamblia Cysteine protease 0.0083 0.0605 0.1733
Brugia malayi hypothetical protein 0.0038 0.0104 0.011
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0049 0.0231 0.0224
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0156 0.1418 0.1411
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0328 0.0569
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0104 0.0126
Leishmania major hypothetical protein, unknown function 0.0099 0.0786 0.1677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Onchocerca volvulus 0.0122 0.1036 0.18
Toxoplasma gondii cathepsin B 0.0326 0.3313 0.9464
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.0231 0.0493
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0099 0.0786 0.0811
Trypanosoma cruzi oligopeptidase b 0.0052 0.0261 0.0247
Mycobacterium ulcerans proteasome PrcB 0.0155 0.1402 0.989
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.1779 0.3907
Echinococcus granulosus glycoprotein Antigen 5 0.0156 0.1418 0.1411
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.1779 0.5029
Toxoplasma gondii centrin 0.0049 0.0231 0.0639
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0099 0.0786 0.1473
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0351 0.0344
Entamoeba histolytica hypothetical protein 0.0038 0.0104 0.0191
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0926 0.9992 0.9992
Trichomonas vaginalis calpain, putative 0.0099 0.0786 0.1473
Brugia malayi Delta serrate ligand family protein 0.0049 0.0224 0.0238
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.7385
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0506 0.0536
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0481 0.0927
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0049 0.0231 0.0558
Leishmania major cathepsin L-like protease 0.0436 0.4542 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0605 0.1116
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0156 0.1418 0.1502
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0099 0.0786 0.1473
Trichomonas vaginalis calmodulin, putative 0.0049 0.0231 0.0377
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0083 0.0605 0.0606
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0331 0.3362 0.3571
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0083 0.0605 0.1712
Echinococcus multilocularis caspase 3 0.0072 0.0484 0.0477
Echinococcus multilocularis glycoprotein Antigen 5 0.0156 0.1418 0.1411
Onchocerca volvulus 0.0049 0.0231 0.0401
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Echinococcus granulosus fibropellin Ia 0.0049 0.0224 0.0217
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0481 0.1357
Onchocerca volvulus Chorion peroxidase homolog 0.0419 0.4344 0.7543
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0049 0.0231 0.0224
Echinococcus multilocularis calcium uptake protein 1 0.005 0.0238 0.0231
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0104 0.011
Entamoeba histolytica grainin, putative 0.005 0.0238 0.058
Onchocerca volvulus 0.0075 0.0513 0.0891
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0118 0.0988 0.1992
Echinococcus granulosus cathepsin l cysteine peptidase 0.0343 0.35 0.3495
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.004 0.0006
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.004 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0331 0.3362 0.3571
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0328 0.0347
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0224 0.0238
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0052 0.0261 0.0559
Trichomonas vaginalis calcineurin B subunit, putative 0.0049 0.0231 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0083 0.0605 0.1116
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0045 0.0178 0.0488
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0139 0.1229 0.2347
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0481 0.0871
Echinococcus multilocularis Mastin 0.0156 0.1418 0.1411
Onchocerca volvulus Prolyl endopeptidase homolog 0.0131 0.1142 0.1982
Brugia malayi Calmodulin-like protein 0.0049 0.0231 0.0244
Loa Loa (eye worm) hypothetical protein 0.0072 0.0481 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0785 0.0786
Echinococcus granulosus calbindin 32 0.005 0.0238 0.0231
Loa Loa (eye worm) hypothetical protein 0.0072 0.0481 0.051
Brugia malayi Cadherin domain containing protein 0.0049 0.0224 0.0238
Brugia malayi Cathepsin L-like precursor 0.0105 0.0853 0.0903
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0446 0.0472
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.004 0.0092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0436 0.4542 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni hypothetical protein 0.0049 0.0231 0.0231
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0446 0.0439
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0104 0.0104
Echinococcus multilocularis neurogenic locus protein delta 0.0049 0.0224 0.0217
Trypanosoma brucei cysteine peptidase, putative 0.0099 0.0786 0.1718
Plasmodium vivax vivapain-2 0.0343 0.35 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0343 0.35 0.6827
Giardia lamblia Cathepsin L precursor 0.0083 0.0605 0.1733
Echinococcus granulosus peroxidasin 0.0419 0.4344 0.434
Loa Loa (eye worm) hypothetical protein 0.0105 0.0853 0.0903
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0312 0.0872
Entamoeba histolytica cysteine protease, putative 0.0188 0.1779 0.5029
Giardia lamblia Cathepsin L-like protease 0.0083 0.0605 0.1733
Brugia malayi EF hand family protein 0.005 0.0238 0.0253
Brugia malayi Protein kinase domain containing protein 0.0068 0.0434 0.046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0605 0.1116

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.237 uM Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry ChEMBL. 20537544
IC50 (functional) = 7.79 uM Antiproliferative activity against human A549 cells after 24 hrs by SRB assay ChEMBL. 20537544

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 20537544

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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