Detailed information for compound 1363448

Basic information

Technical information
  • TDR Targets ID: 1363448
  • Name: methyl 2-(2-aminophenyl)sulfanyl-6-methylpyri midine-4-carboxylate
  • MW: 275.326 | Formula: C13H13N3O2S
  • H donors: 1 H acceptors: 3 LogP: 2.51 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1nc(nc(c1)C)Sc1ccccc1N
  • InChi: 1S/C13H13N3O2S/c1-8-7-10(12(17)18-2)16-13(15-8)19-11-6-4-3-5-9(11)14/h3-7H,14H2,1-2H3
  • InChiKey: QAUJLCZVDJWYBL-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • methyl 2-(2-aminophenyl)sulfanyl-6-methyl-pyrimidine-4-carboxylate
  • 2-[(2-aminophenyl)thio]-6-methyl-4-pyrimidinecarboxylic acid methyl ester
  • 2-[(2-aminophenyl)thio]-6-methyl-pyrimidine-4-carboxylic acid methyl ester
  • IDI1_019003
  • ZINC00126906
  • MLS000835010
  • SMR000461626
  • Maybridge3_007616
  • methyl 2-[(2-aminophenyl)sulfanyl]-6-methyl-4-pyrimidinecarboxylate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Homo sapiens pyruvate kinase, muscle Starlite/ChEMBL No references
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Bacillus subtilis 4'-phosphopantetheinyl transferase ffp Starlite/ChEMBL No references
Trypanosoma brucei hypothetical protein, conserved Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Toxoplasma gondii pyruvate kinase PyK1 Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum expressed protein Get druggable targets OG5_129301 All targets in OG5_129301
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Chlamydia trachomatis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Get druggable targets OG5_129301 All targets in OG5_129301
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00873 pyruvate kinase [EC2.7.1.40], putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Plasmodium yoelii pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium hominis proteinx0005 Get druggable targets OG5_129301 All targets in OG5_129301
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma brucei gambiense hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Babesia bovis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei pyruvate kinase 1 Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Pyruvate kinase, muscle isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis L aminoadipate semialdehyde Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani HpcH/HpaI aldolase/citrate lyase family, putative Get druggable targets OG5_146801 All targets in OG5_146801
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus multilocularis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Candida albicans pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma cruzi pyruvate kinase 2, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma brucei gambiense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Onchocerca volvulus Pyruvate kinase homolog Get druggable targets OG5_126685 All targets in OG5_126685
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126685 All targets in OG5_126685
Brugia malayi Pyruvate kinase, M2 isozyme Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium parvum phosphopantetheinyl transferase Get druggable targets OG5_129301 All targets in OG5_129301
Loa Loa (eye worm) pyruvate kinase-PB Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei pyruvate kinase, putative Get druggable targets OG5_126685 All targets in OG5_126685
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Trypanosoma congolense pyruvate kinase 1, putative Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K00142 aminoadipate-semialdehyde dehydrogenase [EC1.2.1.31], putative Get druggable targets OG5_129301 All targets in OG5_129301
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum Pyruvate kinase isozyme R, putative Get druggable targets OG5_126685 All targets in OG5_126685
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana hypothetical protein, conserved Get druggable targets OG5_146801 All targets in OG5_146801
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum Pyruvate kinase (EC 2.7.1.40), related Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae Probable pyruvate kinase PykA Get druggable targets OG5_126685 All targets in OG5_126685
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia Pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Schistosoma mansoni pyruvate kinase Get druggable targets OG5_126685 All targets in OG5_126685
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Entamoeba histolytica hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 198 aa 28.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Echinococcus granulosus pyruvate kinase pyruvate kinase, muscle 605 aa 521 aa 34.9 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Onchocerca volvulus 4'-phosphopantetheinyl transferase ffp   224 aa 186 aa 26.3 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Trichomonas vaginalis conserved hypothetical protein 4'-phosphopantetheinyl transferase ffp   224 aa 197 aa 22.3 %
Candida albicans aminoadipate-semialdehyde dehydrogenase small subunit 4'-phosphopantetheinyl transferase ffp   224 aa 183 aa 27.3 %
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Regulator of G protein signaling 20 0.0043 0.0063 0.0062
Giardia lamblia Cathepsin L precursor 0.0339 0.0872 0.2359
Trypanosoma brucei pyruvate kinase 1, putative 0.004 0.0055 0.0083
Loa Loa (eye worm) notch protein 0.0026 0.0016 0.0015
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0021 0.0031
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.0257 0.0256
Loa Loa (eye worm) hypothetical protein 0.0502 0.1317 0.1316
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.004 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0002
Schistosoma mansoni pyruvate kinase 0.004 0.0055 0.0054
Leishmania major proteasome alpha 3 subunit, putative 0.004 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.004 0.0054 0.0081
Leishmania major calcineurin B subunit, putative 0.0158 0.0377 0.0577
Trichomonas vaginalis calpain, putative 0.0293 0.0745 0.2
Brugia malayi hypothetical protein 0.0138 0.0321 0.032
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.001 0.0009
Brugia malayi Proteasome subunit alpha type 7-1 0.004 0.0054 0.0053
Trypanosoma brucei calpain-like protein, putative 0.0993 0.2663 0.4085
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0052 0.0051
Onchocerca volvulus 0.1381 0.3724 0.5708
Onchocerca volvulus 0.1654 0.447 0.6856
Mycobacterium leprae Probable lipase LipE 0.0039 0.0052 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0077 0.0156 0.0155
Echinococcus granulosus apoptotic protease activating factor 1 0.0138 0.0321 0.032
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0054 0.0053
Echinococcus granulosus importin subunit beta 1 0.0028 0.0021 0.002
Echinococcus granulosus histone deacetylase 7 0.0099 0.0214 0.0213
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0993 0.2663 0.2662
Trypanosoma brucei proteasome beta 3 subunit, putative 0.004 0.0054 0.0081
Giardia lamblia Cysteine protease 0.0339 0.0872 0.2359
Leishmania major centrin, putative 0.0158 0.0377 0.0577
Trypanosoma cruzi conserved protein 0.0293 0.0745 0.0745
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.001 0.0009
Schistosoma mansoni histone deacetylase 0.0088 0.0185 0.0184
Giardia lamblia Hypothetical protein 0.0339 0.0872 0.2359
Trichomonas vaginalis glycogen phosphorylase, putative 0.0118 0.0269 0.0719
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.0219 0.0219
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0058
Brugia malayi histone deacetylase 11 0.0042 0.006 0.006
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0295 0.0294
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0099 0.0098
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0056 0.01
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1371 0.3695 0.567
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0168
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0066 0.01
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0021 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Echinococcus granulosus calpain A 0.0993 0.2663 0.2662
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0339 0.0872 0.0871
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0021 0.0055
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0056 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Schistosoma mansoni glycogen phosphorylase 0.0051 0.0085 0.0084
Echinococcus multilocularis programmed cell death protein 0.0162 0.0387 0.0386
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.4085
Trypanosoma cruzi cysteine peptidase, putative 0.1487 0.4014 0.4013
Plasmodium falciparum plasmepsin I 0.0031 0.003 0.0078
Brugia malayi Cytochrome P450 family protein 0.0036 0.0042 0.0041
Trypanosoma cruzi cruzipain precursor, putative 0.1487 0.4014 0.4013
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.0191 0.019
Mycobacterium tuberculosis Conserved protein 0.0039 0.0052 0.0092
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0062
Brugia malayi Papain family cysteine protease containing protein 0.0339 0.0872 0.0871
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0054 0.0081
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0063 0.0062
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0041 0.0109
Plasmodium falciparum pyruvate kinase 2 0.0021 0.0001 0.0001
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0032 0.0031
Brugia malayi proteasome subunit alpha type 3 0.004 0.0054 0.0053
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0023 0.0059
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0137 0.032 0.0865
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0007 0.0015
Trypanosoma cruzi centrin-3 0.0162 0.0387 0.0386
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3674 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0075 0.0074
Loa Loa (eye worm) hypothetical protein 0.0042 0.006 0.006
Echinococcus granulosus caspase 3 0.0073 0.0145 0.0144
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0339 0.0872 0.2341
Echinococcus multilocularis neurogenic locus notch protein 4 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Onchocerca volvulus Cathepsin L homolog 0.1381 0.3724 0.5708
Loa Loa (eye worm) hypothetical protein 0.0315 0.0808 0.0807
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0339 0.0872 0.2341
Brugia malayi calpain D 0.0293 0.0745 0.0745
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0026 0.0016 0.0015
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0339 0.0872 0.0871
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0016 0.0015
Toxoplasma gondii subtilisin SUB12 0.0031 0.0029 0.0043
Echinococcus multilocularis EF hand domain containing family member A2 0.0161 0.0384 0.0383
Schistosoma mansoni notch 0.0026 0.0016 0.0015
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0059 0.0058
Brugia malayi Cell death protein 3 precursor 0.0182 0.0443 0.0442
Schistosoma mansoni neuronal calcium sensor 0.0158 0.0377 0.0376
Trypanosoma brucei antigen, putative 0.0993 0.2663 0.4085
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0021 0.0032
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.003 0.0026 0.0045
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.006 0.006
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.0284 0.0283
Schistosoma mansoni cpg binding protein 0.0033 0.0034 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0051
Schistosoma mansoni hypothetical protein 0.0291 0.0741 0.074
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.0257 0.0256
Trypanosoma cruzi cysteine peptidase, putative 0.1381 0.3724 0.3723
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.004 0.0054 0.0142
Schistosoma mansoni importin beta-1 0.0028 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0339 0.0872 0.0871
Leishmania major hypothetical protein, conserved 0.0293 0.0745 0.1143
Echinococcus multilocularis citrate lyase subunit beta protein 0.003 0.0026 0.0025
Giardia lamblia Hypothetical protein 0.0339 0.0872 0.2359
Echinococcus granulosus 20S proteasome subunit alpha 6 0.004 0.0054 0.0053
Schistosoma mansoni hypothetical protein 0.0138 0.0321 0.032
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0142 0.0333 0.0332
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0168
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0054 0.0053
Schistosoma mansoni cathepsin F (C01 family) 0.1381 0.3724 0.3723
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.001 0.0009
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0054 0.0053
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Echinococcus granulosus prolyl endopeptidase 0.2401 0.6516 0.6516
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0021 0.0031
Giardia lamblia Cathepsin L precursor 0.0339 0.0872 0.2359
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0224 0.0223
Brugia malayi proteasome subunit beta type 2 0.009 0.0191 0.019
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0032 0.0048
Giardia lamblia 20S proteasome alpha subunit 1 0.004 0.0054 0.0143
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0056 0.0149
Giardia lamblia Proteasome subunit beta type 9 precursor 0.004 0.0054 0.0143
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.004 0.0054 0.0142
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0247 0.0619 0.0618
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.0086 0.0085
Onchocerca volvulus 0.0031 0.0029 0.003
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0142 0.0333 0.0509
Onchocerca volvulus 0.0026 0.0016 0.001
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.078 0.2079 0.2079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0339 0.0872 0.2341
Echinococcus granulosus tumor protein p63 0.0385 0.0999 0.0998
Echinococcus granulosus caspase 2 0.0182 0.0443 0.0442
Brugia malayi Fli-1 protein 0.0218 0.0542 0.0541
Trypanosoma cruzi centrin, putative 0.0162 0.0387 0.0386
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.0054 0.0053
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0052 0.0138
Plasmodium vivax proteasome subunit beta type-3, putative 0.004 0.0054 0.0142
Schistosoma mansoni septate junction protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0959 0.2568 0.2567
Toxoplasma gondii hypothetical protein 0.0293 0.0745 0.1143
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0064 0.0063
Echinococcus multilocularis proteasome subunit alpha type 2 0.004 0.0054 0.0053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0041 0.0108
Entamoeba histolytica cysteine protease, putative 0.0339 0.0872 0.2341
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0007 0.0015
Echinococcus granulosus proteasome prosome macropain 0.0247 0.0619 0.0618
Echinococcus multilocularis calmodulin 0.0158 0.0377 0.0376
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0158 0.0378 0.0377
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0224 0.0223
Echinococcus granulosus slit 2 protein 0.0026 0.0016 0.0015
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0158 0.0377 0.0376
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0032 0.0108
Toxoplasma gondii proteasome subunit beta type 2, putative 0.009 0.0191 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0175
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0044 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0056 0.0099 0.0098
Toxoplasma gondii pyruvate kinase PyKII 0.0021 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0028 0.0022 0.0057
Loa Loa (eye worm) animal heme peroxidase 0.032 0.0819 0.0819
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.001 0.0009
Entamoeba histolytica prolyl oligopeptidase family protein 0.0315 0.0808 0.2167
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0032 0.0048
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0998 0.2675 1
Plasmodium vivax aspartyl protease, putative 0.0112 0.0251 0.0672
Plasmodium vivax serine-repeat antigen (SERA) 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.1946 0.5271 0.5271
Mycobacterium tuberculosis Conserved protein 0.0039 0.0052 0.0092
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.0054 0.0081
Echinococcus granulosus calpain A 0.2808 0.7628 0.7628
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0339 0.0872 0.2341
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.0054 0.0053
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0066 0.01
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0339 0.0872 0.0871
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0808 0.2167
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0102 0.0224 0.0397
Mycobacterium leprae probable zinc metalloprotease 0.0102 0.0224 0.0762
Echinococcus granulosus tissue type plasminogen activator 0.0048 0.0075 0.0074
Loa Loa (eye worm) EF hand family protein 0.0158 0.0377 0.0376
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0052 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0339 0.0872 0.2341
Toxoplasma gondii hypothetical protein 0.0031 0.0029 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1371 0.3695 0.3695
Toxoplasma gondii proteasome subunit beta type, putative 0.0247 0.0619 0.0949
Echinococcus granulosus histone deacetylase 3 0.0088 0.0185 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.001 0.0009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0339 0.0872 0.0871
Schistosoma mansoni thyroid hormone receptor 0.0024 0.001 0.0009
Giardia lamblia High cysteine protein 0.0026 0.0016 0.0041
Brugia malayi beta-lactamase family protein 0.0039 0.0052 0.0051
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0025 0.0013 0.0012
Leishmania major hypothetical protein, conserved 0.0161 0.0384 0.0588
Onchocerca volvulus 0.0031 0.0029 0.003
Plasmodium falciparum proteasome subunit beta type-5 0.0247 0.0619 0.1661
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Onchocerca volvulus 0.1381 0.3724 0.5708
Mycobacterium tuberculosis Long conserved protein 0.0291 0.0741 0.131
Schistosoma mansoni notch 0.0026 0.0017 0.0016
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.2086 0.5653 1
Leishmania major cathepsin L-like protease 0.1487 0.4014 0.6159
Onchocerca volvulus Neurogenic locus notch homolog 0.0026 0.0017 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0124 0.0284 0.0761
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0043 0.0063 0.0062
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.0191 0.019
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0016 0.0015
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0247 0.0619 0.1674
Brugia malayi Proteasome A-type and B-type family protein 0.0247 0.0619 0.0618
Echinococcus multilocularis protein jagged 1 0.0026 0.0016 0.0015
Schistosoma mansoni caspase-7 (C14 family) 0.0182 0.0443 0.0442
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0052 0.0092
Onchocerca volvulus 0.0031 0.0029 0.003
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.004 0.0054 0.0053
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0915 0.245 0.2449
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1381 0.3724 1
Giardia lamblia Alanyl dipeptidyl peptidase 0.0315 0.0808 0.2184
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0032 0.0057
Loa Loa (eye worm) hypothetical protein 0.0158 0.0377 0.0376
Giardia lamblia Cathepsin B precursor 0.1371 0.3695 1
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0056 0.0149
Brugia malayi calpain 7 0.0993 0.2663 0.2662
Brugia malayi EF hand family protein 0.0158 0.0377 0.0376
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0032 0.0108
Echinococcus granulosus neuronal calcium sensor 0.0158 0.0377 0.0376
Echinococcus granulosus calumenin 0.0161 0.0384 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0175
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0013 0.0012
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0339 0.0872 0.2341
Echinococcus granulosus caspase 0.0118 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0137 0.032 0.032
Trichomonas vaginalis calcium binding protein, putative 0.0158 0.0377 0.101
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0339 0.0872 0.2341
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.006 0.0091
Schistosoma mansoni cpg binding protein 0.0035 0.0039 0.0038
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2401 0.6516 0.6516
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0016 0.0015
Leishmania major cathepsin L-like protease 0.1487 0.4014 0.6159
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.004 0.0054 0.0142
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0054 0.0053
Trypanosoma brucei Calpain-like protein 1.2 0.0293 0.0745 0.1143
Onchocerca volvulus 0.0048 0.0075 0.0101
Mycobacterium ulcerans lipase LipD 0.0039 0.0052 0.0184
Entamoeba histolytica hypothetical protein, conserved 0.0315 0.0808 0.2167
Onchocerca volvulus 0.0161 0.0384 0.0576
Brugia malayi Importin beta-1 subunit 0.0028 0.0021 0.002
Plasmodium falciparum calpain 0.0293 0.0745 0.2
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0295 0.0294
Toxoplasma gondii proteasome subunit alpha1, putative 0.004 0.0054 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.001 0.0009
Brugia malayi Peptidase family M13 containing protein 0.0102 0.0224 0.0223
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0185 0.0184
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0247 0.0619 0.1096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3674 1 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0247 0.0619 0.1661
Echinococcus multilocularis beta adrenergic receptor kinase 0.0044 0.0064 0.0063
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0141 0.033 0.0584
Schistosoma mansoni thyroid hormone receptor 0.0024 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0077 0.0156 0.0155
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0052 0.0086 0.0085
Giardia lamblia Cathepsin B precursor 0.0339 0.0872 0.2359
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.001 0.0009
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.0055 0.0145
Loa Loa (eye worm) glutathione reductase 0.0057 0.0101 0.01
Echinococcus granulosus proteasome prosome macropain subunit beta 0.009 0.0191 0.019
Echinococcus granulosus EF hand domain containing family member A2 0.0158 0.0377 0.0376
Schistosoma mansoni hypothetical protein 0.0027 0.0018 0.0017
Echinococcus multilocularis enteropeptidase 0.016 0.0381 0.038
Trichomonas vaginalis calmodulin, putative 0.0161 0.0384 0.103
Toxoplasma gondii calcium-dependent protein kinase 0.0161 0.0385 0.059
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0158 0.0377 0.101
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0185 0.0494
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0247 0.0619 0.0618
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.0138 0.0321 0.032
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0022
Echinococcus granulosus glycogen phosphorylase 0.0118 0.0269 0.0268
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0064 0.0063
Brugia malayi Cathepsin L-like cysteine proteinase 0.0959 0.2568 0.2567
Onchocerca volvulus Cathepsin F homolog 0.1381 0.3724 0.5708
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0063 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0339 0.0872 0.2341
Loa Loa (eye worm) sirtuin 4 0.0032 0.0032 0.0031
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Loa Loa (eye worm) PXA domain-containing protein 0.0043 0.0063 0.0062
Brugia malayi proteasome subunit beta type 3 0.004 0.0054 0.0053
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0247 0.0619 0.0618
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.0284 0.0761
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0056 0.0056
Brugia malayi Blistered cuticle protein 3 0.032 0.0819 0.0819
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0102 0.0224 0.0223
Giardia lamblia Cathepsin B precursor 0.1371 0.3695 1
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0032 0.0031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0054 0.0142
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0998 0.2675 0.2674
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.001 0.0009
Loa Loa (eye worm) histone deacetylase 0.0099 0.0214 0.0213
Toxoplasma gondii pyruvate kinase PyK1 0.004 0.0055 0.0083
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0023 0.0041
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0998 0.2675 0.2674
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Plasmodium vivax importin-beta 2, putative 0.0028 0.0021 0.0054
Onchocerca volvulus 0.0033 0.0034 0.0038
Echinococcus multilocularis notch 0.0026 0.0016 0.0015
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0745 0.0745
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0152 0.0361 0.036
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0028
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Plasmodium falciparum serine repeat antigen 4 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Schistosoma mansoni hemoglobinase (C13 family) 0.0152 0.0361 0.036
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0293 0.0745 0.0745
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.006 0.0078
Onchocerca volvulus Slit protein homolog 0.0026 0.0016 0.001
Schistosoma mansoni memapsin-2 (A01 family) 0.0503 0.1321 0.132
Loa Loa (eye worm) hypothetical protein 0.0077 0.0156 0.0155
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0654 0.1735 0.2662
Schistosoma mansoni cathepsin C 0.0339 0.0872 0.0871
Leishmania major pyruvate kinase 0.004 0.0055 0.0083
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0063 0.0062
Plasmodium vivax proteasome subunit alpha type-4, putative 0.004 0.0054 0.0142
Schistosoma mansoni reticulocalbin 0.0158 0.0377 0.0376
Brugia malayi prolyl oligopeptidase family protein 0.2401 0.6516 0.6516
Trypanosoma cruzi I/6 autoantigen, putative 0.0158 0.0377 0.0376
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Schistosoma mansoni centrin 0.0158 0.0377 0.0376
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3674 1 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.001 0.0009
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0158 0.0377 0.101
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0021 0.0021
Trypanosoma brucei C-8 sterol isomerase, putative 0.0365 0.0943 0.1446
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Trypanosoma cruzi kinesin, putative 0.0701 0.1862 0.1861
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0044 0.0064 0.0063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0052 0.0092
Plasmodium falciparum plasmepsin II 0.0031 0.003 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Brugia malayi Papain family cysteine protease containing protein 0.1381 0.3724 0.3723
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.0166
Brugia malayi Papain family cysteine protease containing protein 0.0761 0.2028 0.2028
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0032 0.0031
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.0341 0.0603
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0059 0.0157
Onchocerca volvulus 0.016 0.0381 0.0571
Schistosoma mansoni slit 0.0026 0.0016 0.0015
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0185 0.0184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0031 0.003 0.0029
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0422 0.1101 0.11
Leishmania major hypothetical protein, conserved 0.0257 0.0648 0.0993
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.004 0.0054 0.0142
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.006 0.006
Giardia lamblia Hypothetical protein 0.0124 0.0284 0.0767
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.2662
Leishmania major pyruvate kinase 0.004 0.0055 0.0083
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0998 0.2675 0.4732
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Brugia malayi regulator of G-protein signaling egl-10 0.0043 0.0063 0.0062
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.032 0.0858
Echinococcus granulosus enteropeptidase 0.016 0.0381 0.038
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0066 0.01
Plasmodium vivax proteasome subunit beta type-6, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) proteasome subunit beta type 2 0.009 0.0191 0.019
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0026 0.0025
Echinococcus granulosus subfamily T1A non peptidase ue 0.004 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi Animal haem peroxidase family protein 0.032 0.0819 0.0819
Giardia lamblia Proteasome subunit beta type 2 0.009 0.0191 0.0514
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0993 0.2663 0.2662
Entamoeba histolytica proteasome subunit beta type 3, putative 0.004 0.0054 0.0142
Brugia malayi calcium-binding protein 0.0158 0.0377 0.0376
Trypanosoma brucei proteasome beta 7 subunit 0.004 0.0054 0.0081
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0124 0.0284 0.0283
Leishmania major calmodulin, putative 0.0158 0.0377 0.0577
Trypanosoma brucei protein I/6 0.0158 0.0377 0.0577
Trichomonas vaginalis glycogen phosphorylase, putative 0.0118 0.0269 0.0719
Onchocerca volvulus 0.0056 0.0099 0.0137
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0023 0.0041
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1212 0.3262 0.3262
Schistosoma mansoni coup transcription factor 0.0024 0.001 0.0009
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0214 0.0213
Trichomonas vaginalis Citrate lyase beta chain, putative 0.003 0.0026 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Plasmodium vivax hypothetical protein, conserved 0.0161 0.0384 0.103
Echinococcus granulosus glycogen phosphorylase 0.0118 0.0269 0.0268
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.004 0.0054 0.0053
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Plasmodium vivax vivapain-2 0.1381 0.3724 1
Echinococcus granulosus protein jagged 1 0.0026 0.0016 0.0015
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0032 0.0031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0124 0.0284 0.0761
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0293 0.0745 0.2
Schistosoma mansoni survival motor neuron protein 0.0102 0.0225 0.0224
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0056 0.0149
Echinococcus multilocularis histone deacetylase 6 0.0105 0.0231 0.023
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0102 0.0224 0.0223
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.004 0.0054 0.0142
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.009 0.0191 0.019
Echinococcus granulosus protein jagged 2 0.0026 0.0016 0.0015
Plasmodium falciparum cysteine proteinase falcipain 3 0.1381 0.3724 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0052 0.0138
Onchocerca volvulus 0.01 0.0219 0.0323
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0052 0.0138
Echinococcus granulosus cathepsin b 0.3674 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Plasmodium falciparum histone deacetylase 2 0.0099 0.0214 0.0573
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0339 0.0872 0.2341
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0808 0.2167
Schistosoma mansoni calmodulin 0.0158 0.0377 0.0376
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0056 0.0085
Trypanosoma cruzi major cysteine proteinase, putative 0.0445 0.1162 0.1162
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0339 0.0872 0.2341
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.001 0.0009
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0054 0.0142
Echinococcus granulosus survival motor neuron protein 1 0.0502 0.1317 0.1316
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0063 0.0062
Schistosoma mansoni neuronal calcium sensor 0.0158 0.0377 0.0376
Schistosoma mansoni ets-related 0.0218 0.0542 0.0541
Loa Loa (eye worm) pyruvate kinase-PB 0.0028 0.0022 0.0021
Entamoeba histolytica calpain family cysteine protease, putative 0.0293 0.0745 0.2
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0998 0.2675 0.4104
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0023 0.0034
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.0054 0.0053
Loa Loa (eye worm) zinc metallopeptidase 4 0.0025 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0102 0.0225 0.0224
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.0172 0.0416 0.0415
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0032 0.0083
Echinococcus granulosus snurportin 1 0.0298 0.076 0.076
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0293 0.0745 0.0745
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1381 0.3724 0.3723
Plasmodium vivax vivapain-2 0.1381 0.3724 1
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0141 0.014
Trypanosoma brucei Component of motile flagella 41 0.0158 0.0377 0.0577
Loa Loa (eye worm) calpain family protein 1 0.2647 0.7189 0.7188
Trypanosoma brucei centrin, putative 0.0158 0.0377 0.0577
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0054 0.0053
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0022 0.007
Toxoplasma gondii microneme protein, putative 0.0031 0.0029 0.0043
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0293 0.0745 0.2
Schistosoma mansoni z-protein (S1r protein) 0.0043 0.0063 0.0062
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0654 0.1735 0.1735
Brugia malayi Trypsin family protein 0.016 0.0381 0.038
Onchocerca volvulus 0.0031 0.0029 0.003
Loa Loa (eye worm) animal heme peroxidase 0.032 0.0819 0.0819
Brugia malayi Protein kinase domain containing protein 0.0048 0.0075 0.0074
Echinococcus granulosus Regulator of G protein signaling 20 0.0043 0.0063 0.0062
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0043 0.0063 0.0062
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Echinococcus multilocularis fat cadherin tumor suppressor 0.0026 0.0016 0.0015
Onchocerca volvulus 0.0031 0.0029 0.003
Brugia malayi Animal haem peroxidase family protein 0.032 0.0819 0.0819
Trypanosoma brucei mitochondrial calcium uptake 1 0.0158 0.0377 0.0577
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.0632 0.1118
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0124 0.019
Schistosoma mansoni calpain-2 (C02 family) 0.0293 0.0745 0.0745
Entamoeba histolytica calpain large subunit domain III containing protein 0.0701 0.1862 0.4999
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.004 0.0054 0.9205
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.0054 0.0053
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0158 0.0377 0.0376
Echinococcus multilocularis calbindin 32 0.0161 0.0384 0.0383
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0066 0.01
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0028
Leishmania major calmodulin, putative 0.0158 0.0377 0.0577
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0032 0.0083
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.004 0.0054 0.0053
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0023 0.0034
Toxoplasma gondii histone deacetylase HDAC1 0.0099 0.0214 0.0327
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0056 0.0056
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1371 0.3695 0.3695
Schistosoma mansoni calpain-7 (C02 family) 0.0996 0.2671 0.267
Mycobacterium ulcerans putative transglutaminase-like protein 0.0291 0.0741 0.276
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0059 0.0058
Echinococcus multilocularis neurocalcin 0.0158 0.0377 0.0376
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Loa Loa (eye worm) proteasome subunit alpha type 3 0.004 0.0054 0.0053
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0101 0.0269
Mycobacterium tuberculosis Probable peptidase 0.0998 0.2675 0.4732
Schistosoma mansoni histone deacetylase hda2 0.0042 0.006 0.006
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0365 0.0943 0.0942
Plasmodium vivax proteasome subunit beta type-4, putative 0.004 0.0054 0.0142
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0185 0.0282
Plasmodium vivax proteasome subunit alpha type-5, putative 0.004 0.0054 0.0142
Plasmodium falciparum glutathione reductase 0.0057 0.0101 0.0269
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0023 0.0074
Giardia lamblia 20S proteasome alpha subunit 2 0.004 0.0054 0.0143
Plasmodium vivax proteasome subunit alpha type-7, putative 0.004 0.0054 0.0142
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0339 0.0872 0.2359
Echinococcus granulosus fibropellin Ia 0.0026 0.0016 0.0015
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0102 0.0224 0.0223
Giardia lamblia Proteasome subunit beta type 1 0.0142 0.0333 0.0898
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0339 0.0872 0.0871
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.001 0.0009
Toxoplasma gondii proteasome beta subunit 0.004 0.0054 0.0081
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0016 0.0015
Brugia malayi Pyruvate kinase, M2 isozyme 0.004 0.0055 0.0054
Onchocerca volvulus Cathepsin L homolog 0.1381 0.3724 0.5708
Schistosoma mansoni endothelin-converting enzyme-related 0.0025 0.0013 0.0012
Plasmodium falciparum histone deacetylase 1 0.0088 0.0185 0.0494
Brugia malayi aspartic protease BmAsp-2, identical 0.0031 0.003 0.0029
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0214 0.0213
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Echinococcus multilocularis slit 2 protein 0.0026 0.0016 0.0015
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2401 0.6516 0.6516
Schistosoma mansoni hypothetical protein 0.0027 0.0018 0.0017
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Plasmodium vivax proteasome subunit beta type-7, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Brugia malayi regulator of G-protein signaling rgs-7 0.0043 0.0063 0.0062
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Leishmania major importin beta-1 subunit, putative 0.0023 0.0007 0.0009
Entamoeba histolytica prolyl oligopeptidase family protein 0.0315 0.0808 0.2167
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2805 0.7621 0.7621
Onchocerca volvulus 0.032 0.0819 0.1245
Loa Loa (eye worm) hypothetical protein 0.0102 0.0224 0.0223
Trypanosoma brucei calpain-like protein, putative 0.0993 0.2663 0.4085
Onchocerca volvulus Peroxidasin homolog 0.032 0.0819 0.1245
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.004 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Plasmodium falciparum plasmepsin VI 0.0031 0.003 0.0078
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0185 0.0184
Schistosoma mansoni gamma-secretase subunit aph-1 0.0267 0.0676 0.0675
Schistosoma mansoni cathepsin B (C01 family) 0.0339 0.0872 0.0871
Entamoeba histolytica cysteine protease, putative 0.0339 0.0872 0.2341
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0158 0.0377 0.101
Leishmania major sir2-family protein-like protein 0.0032 0.0032 0.0048
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0654 0.1735 0.1735
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0185 0.0494
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Entamoeba histolytica grainin, putative 0.0161 0.0384 0.103
Brugia malayi Peptidase C13 family protein 0.0152 0.0361 0.036
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Onchocerca volvulus 0.032 0.0819 0.1245
Brugia malayi Pre-SET motif family protein 0.0708 0.1881 0.1881
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0023 0.0034
Schistosoma mansoni chromatin regulatory protein sir2 0.0137 0.032 0.032
Trichomonas vaginalis pyruvate kinase, putative 0.004 0.0055 0.0145
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0052 0.0051
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.0257 0.0393
Plasmodium falciparum serine repeat antigen 1 0.0339 0.0872 0.2341
Echinococcus multilocularis survival motor neuron protein 1 0.0502 0.1317 0.1316
Echinococcus granulosus cathepsin L 0.0761 0.2028 0.2028
Onchocerca volvulus 0.0026 0.0016 0.001
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Giardia lamblia Cathepsin B precursor 0.0339 0.0872 0.2359
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.001 0.0009
Onchocerca volvulus Chorion peroxidase homolog 0.032 0.0819 0.1245
Toxoplasma gondii hypothetical protein 0.0315 0.0808 0.1238
Giardia lamblia Cysteine protease 0.0339 0.0872 0.2359
Trichomonas vaginalis set domain proteins, putative 0.0805 0.2149 0.5769
Schistosoma mansoni cathepsin S (C01 family) 0.0339 0.0872 0.0871
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0214 0.0213
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0051 0.0085 0.015
Echinococcus multilocularis dnaJ subfamily B 0.0466 0.122 0.1219
Giardia lamblia Serine peptidase, putative 0.0042 0.0059 0.0158
Loa Loa (eye worm) hypothetical protein 0.0075 0.0151 0.015
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0043 0.0063 0.0166
Schistosoma mansoni caspase-7 (C14 family) 0.0118 0.0266 0.0266
Plasmodium falciparum plasmepsin VII 0.0031 0.003 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Loa Loa (eye worm) hypothetical protein 0.0062 0.0115 0.0114
Echinococcus multilocularis pyruvate kinase 0.004 0.0055 0.0054
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0052 0.0092
Loa Loa (eye worm) hypothetical protein 0.0339 0.0872 0.0871
Schistosoma mansoni centrin-related 0.0158 0.0377 0.0376
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.0054 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0339 0.0872 0.2341
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0214 0.0213
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0315 0.0808 0.0807
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.004 0.0054 0.0142
Schistosoma mansoni notch 0.0026 0.0016 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0257 0.0648 0.0993
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0051
Plasmodium vivax unspecified product 0.0422 0.1101 0.2954
Toxoplasma gondii heat shock protein hslv, putative 0.004 0.0054 0.0081
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.004 0.0054 0.0081
Schistosoma mansoni calpain (C02 family) 0.0993 0.2663 0.2662
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.0054 0.0053
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Loa Loa (eye worm) glycogen phosphorylase 0.0118 0.0269 0.0268
Chlamydia trachomatis glycogen phosphorylase 0.0118 0.0269 1
Echinococcus granulosus cathepsin L cysteine protease 0.0761 0.2028 0.2028
Trichomonas vaginalis calcineurin B subunit, putative 0.0161 0.0384 0.103
Plasmodium vivax aspartyl protease, putative 0.0112 0.0251 0.0672
Echinococcus multilocularis regulator of G protein signaling 0.0043 0.0063 0.0062
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0915 0.245 0.2449
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0339 0.0872 0.2341
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0064 0.0063
Giardia lamblia Proteasome subunit beta type 3 0.004 0.0054 0.0143
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.0301 0.0533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Echinococcus multilocularis tumor protein p63 0.0385 0.0999 0.0998
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0022 0.0032
Echinococcus multilocularis proteasome subunit alpha type 6 0.004 0.0054 0.0053
Mycobacterium tuberculosis Conserved protein 0.0291 0.0741 0.131
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0003 0.0006
Schistosoma mansoni neuronal calcium sensor 0.0158 0.0377 0.0376
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1381 0.3724 0.3723
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0377 0.101
Toxoplasma gondii aspartyl protease 0.0031 0.003 0.0045
Echinococcus granulosus geminin 0.0174 0.0422 0.0421
Schistosoma mansoni pyruvate kinase 0.004 0.0055 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.004 0.0054 0.012
Trypanosoma cruzi calmodulin, putative 0.0158 0.0377 0.0376
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0998 0.2675 0.4104
Loa Loa (eye worm) Notch2 0.0026 0.0016 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0761 0.2028 0.3112
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Loa Loa (eye worm) transcriptional regulator 0.0124 0.0284 0.0283
Loa Loa (eye worm) prolyl oligopeptidase 0.0915 0.245 0.2449
Loa Loa (eye worm) hypothetical protein 0.0102 0.0224 0.0223
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.004 0.0054 0.0142
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.0219 0.0219
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.004 0.0054 0.0053
Brugia malayi cathepsin L precursor 0.0339 0.0872 0.0871
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0224 0.0223
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0056 1
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi Animal haem peroxidase family protein 0.032 0.0819 0.0819
Brugia malayi glutathione reductase 0.0057 0.0101 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0761 0.2028 0.3112
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0761 0.2028 0.2028
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Brugia malayi Cathepsin L-like precursor 0.1381 0.3724 0.3723
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.016 0.0381 0.038
Trypanosoma brucei cytochrome P450, putative 0.0036 0.0042 0.0064
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3674 1 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.001 0.0009
Toxoplasma gondii cathepsin B 0.1371 0.3695 0.567
Echinococcus granulosus calbindin 32 0.0161 0.0384 0.0383
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0142 0.0333 0.0332
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0032 0.0031
Echinococcus granulosus histone deacetylase 1 0.0088 0.0185 0.0184
Schistosoma mansoni ef hand domain family member A2 0.0158 0.0377 0.0376
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0745 0.0745
Brugia malayi Cathepsin L-like precursor 0.1381 0.3724 0.3723
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0339 0.0872 0.0871
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0342 0.0341
Echinococcus granulosus Transglutaminase 0.0291 0.0741 0.074
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.0257 0.0687
Trypanosoma cruzi I/6 autoantigen, putative 0.0158 0.0377 0.0376
Brugia malayi hypothetical protein 0.032 0.0819 0.0819
Onchocerca volvulus 0.0031 0.0029 0.003
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0063 0.0062
Loa Loa (eye worm) TK/ROR protein kinase 0.0048 0.0075 0.0074
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0041 0.0108
Leishmania major proteasome beta 3 subunit, putative 0.004 0.0054 0.0081
Schistosoma mansoni hypothetical protein 0.016 0.0381 0.038
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0043 0.0063 0.0062
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0054 0.0081
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0054 0.0053
Plasmodium vivax unspecified product 0.0761 0.2028 0.5446
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0032 0.0083
Onchocerca volvulus 0.0031 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.2647 0.7189 0.7188
Toxoplasma gondii kringle domain-containing protein 0.0048 0.0075 0.0114
Leishmania major cytochrome p450-like protein 0.0036 0.0042 0.0064
Brugia malayi Peroxidasin 0.032 0.0819 0.0819
Plasmodium vivax pyruvate kinase 2, putative 0.0021 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, putative 0.0293 0.0745 0.1143
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Brugia malayi hypothetical protein 0.0043 0.0063 0.0062
Echinococcus granulosus cathepsin b 0.3674 1 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Echinococcus granulosus proteasome subunit beta type 7 0.004 0.0054 0.0053
Brugia malayi calpain 5 0.0701 0.1862 0.1861
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.033 0.1223
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.0054 0.0053
Brugia malayi Cytochrome P450 family protein 0.0059 0.0106 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0761 0.2028 0.5446
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0029
Onchocerca volvulus Dual oxidase homolog 0.032 0.0819 0.1245
Loa Loa (eye worm) hypothetical protein 0.0075 0.0151 0.015
Echinococcus granulosus pyruvate kinase 0.004 0.0055 0.0054
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0031 0.003 0.0078
Onchocerca volvulus 0.0051 0.0083 0.0113
Brugia malayi Cadherin domain containing protein 0.0026 0.0016 0.0015
Schistosoma mansoni calmodulin related calcium binding protein 0.0158 0.0377 0.0376
Mycobacterium tuberculosis Conserved protein 0.003 0.0026 0.0045
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0056 0.0149
Trypanosoma cruzi Aph-1 protein, putative 0.0104 0.023 0.0229
Plasmodium falciparum cysteine repeat modular protein 1 0.0048 0.0075 0.0199
Mycobacterium ulcerans hypothetical protein 0.003 0.0026 0.0084
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0184 0.0448 0.0447
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.078 0.2079 0.2079
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0056 0.0056
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0293 0.0745 0.1143
Trypanosoma brucei histone deacetylase, putative 0.0099 0.0214 0.0327
Brugia malayi Pre-SET motif family protein 0.0102 0.0224 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0059 0.0157
Onchocerca volvulus 0.0102 0.0224 0.033
Giardia lamblia Glycogen phosphorylase 0.0118 0.0269 0.0725
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0058
Brugia malayi CXXC zinc finger family protein 0.0033 0.0034 0.0033
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.004 0.0054 0.0095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0052 0.0051
Plasmodium vivax proteasome subunit alpha type-6, putative 0.004 0.0054 0.0142
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0141 0.014
Leishmania major proteasome beta 7 subunit, putative 0.004 0.0054 0.0081
Loa Loa (eye worm) calmodulin-like protein 0.0158 0.0377 0.0376
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.032 0.0858
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0026 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0174 0.0422 0.0421
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.0301 0.0533
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0059 0.009
Loa Loa (eye worm) PAS-3 protein 0.004 0.0054 0.0053
Echinococcus granulosus beta-adrenergic receptor kinase 0.0044 0.0064 0.0063
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0026 0.0084
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0021 0.0055
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.001 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0342 0.0341
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.001 0.0009
Giardia lamblia Cathepsin B precursor 0.0339 0.0872 0.2359
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Brugia malayi prolyl oligopeptidase family protein 0.0654 0.1735 0.1735
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0141 0.014
Entamoeba histolytica hypothetical protein, conserved 0.0161 0.0384 0.103
Leishmania major kinesin, putative 0.0701 0.1862 0.2856
Toxoplasma gondii aspartyl protease ASP3 0.0112 0.0251 0.0384
Loa Loa (eye worm) proteasome subunit beta type 3 0.004 0.0054 0.0053
Echinococcus multilocularis glycoprotein Antigen 5 0.016 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Echinococcus multilocularis subfamily T1A non peptidase ue 0.004 0.0054 0.0053
Trypanosoma cruzi caltractin, putative 0.0158 0.0377 0.0376
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Giardia lamblia 20S proteasome alpha subunit 3 0.004 0.0054 0.0143
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Loa Loa (eye worm) proteasome subunit alpha type 6 0.004 0.0054 0.0053
Plasmodium vivax aspartyl proteinase, putative 0.0031 0.003 0.0078
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Onchocerca volvulus Peroxidase homolog 0.032 0.0819 0.1245
Echinococcus multilocularis snurportin 1 0.0298 0.076 0.076
Entamoeba histolytica cysteine protease, putative 0.0339 0.0872 0.2341
Schistosoma mansoni cathepsin D (A01 family) 0.0125 0.0288 0.0287
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0315 0.0808 0.2167
Leishmania major cathepsin L-like protease 0.1381 0.3724 0.5714
Echinococcus multilocularis calpain family protein 1, d 0.1946 0.5271 0.5271
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0745 0.0745
Plasmodium falciparum serine repeat antigen 8 0.0339 0.0872 0.2341
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0032 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0041 0.004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0212 0.0211
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.004 0.0054 0.0081
Mycobacterium ulcerans hypothetical protein 0.0029 0.0023 0.0074
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.001 0.0009
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0101 0.01
Echinococcus granulosus inhibitor of apoptosis protein 0.0184 0.0448 0.0447
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0142 0.0333 0.0509
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0142 0.0333 0.0891
Plasmodium vivax SET domain protein, putative 0.0102 0.0224 0.06
Toxoplasma gondii centrin, putative 0.0158 0.0377 0.0577
Echinococcus multilocularis programmed cell death protein 0.0162 0.0387 0.0386
Echinococcus granulosus calpain 5 0.0993 0.2663 0.2662
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0003 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0032 0.0083
Loa Loa (eye worm) hypothetical protein 0.0959 0.2568 0.2567
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0339 0.0872 0.2359
Toxoplasma gondii proteasome subunit 0.004 0.0054 0.0081
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.001 0.0009
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0059 0.0157
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0023 0.0074
Loa Loa (eye worm) hypothetical protein 0.0424 0.1105 0.1105
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0056 1
Echinococcus granulosus microtubule associated protein 2 0.1573 0.4251 0.425
Plasmodium falciparum histone deacetylase, putative 0.0099 0.0214 0.0573
Giardia lamblia Pyruvate kinase 0.0021 0.0001 0.0001
Echinococcus multilocularis neurogenic locus protein delta 0.0026 0.0016 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0052 0.0092
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0745 0.0745
Schistosoma mansoni microtubule-associated protein tau 0.1573 0.4251 0.425
Echinococcus granulosus transmembrane protease serine 3 0.016 0.0381 0.038
Brugia malayi cathepsin Z-like cysteine proteinase 0.0339 0.0872 0.0871
Trypanosoma brucei proteasome beta-1 subunit, putative 0.004 0.0054 0.0081
Leishmania major centrin, putative,caltractin, putative 0.0158 0.0377 0.0577
Loa Loa (eye worm) hypothetical protein 0.0077 0.0156 0.0155
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0021 0.0021
Echinococcus multilocularis cpg binding protein 0.0035 0.0039 0.0038
Plasmodium vivax proteasome subunit beta type-1, putative 0.0142 0.0333 0.0891
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0023 0.0059
Echinococcus multilocularis cathepsin L cysteine protease 0.1381 0.3724 0.3723
Brugia malayi GPI-anchor transamidase 0.0035 0.0041 0.004
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.032 0.0858
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0339 0.0872 0.0871
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0052 0.0092
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.001 0.0009
Onchocerca volvulus 0.0031 0.003 0.0031
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0075 0.0151 0.015
Leishmania major trypanothione reductase 0.0057 0.0101 0.0154
Trypanosoma brucei histone deacetylase 1 0.0088 0.0185 0.0282
Brugia malayi cathepsin F-like cysteine proteinase 0.0422 0.1101 0.11
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0059 0.0058
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0342 0.0341
Trypanosoma brucei oligopeptidase b 0.0998 0.2675 0.4104
Plasmodium vivax pyruvate kinase, putative 0.004 0.0055 0.0145
Onchocerca volvulus 0.0172 0.0416 0.0625
Schistosoma mansoni cathepsin F (C01 family) 0.1381 0.3724 0.3723
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0339 0.0872 0.2341
Schistosoma mansoni hypothetical protein 0.0027 0.0018 0.0017
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2401 0.6516 1
Giardia lamblia 20S proteasome alpha subunit 7 0.004 0.0054 0.0143
Brugia malayi Muscle positioning protein 4 0.0026 0.0016 0.0015
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0184 0.0448 0.0447
Trypanosoma brucei proteasome beta 2 subunit, putative 0.004 0.0054 0.0081
Mycobacterium ulcerans pyruvate kinase 0.004 0.0055 0.0193
Trichomonas vaginalis peptide N-glycanase, putative 0.0291 0.0741 0.1987
Echinococcus granulosus proteasome subunit beta type 6 0.004 0.0054 0.0053
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.0054 0.0142
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0085 0.0225
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.0055 0.0054
Echinococcus granulosus programmed cell death protein 0.0162 0.0387 0.0386
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0142 0.0333 0.0891
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0063 0.0062
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0158 0.0377 0.0376
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0158 0.0377 0.0376
Toxoplasma gondii proteasome subunit alpha type, putative 0.004 0.0054 0.0081
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0101 0.01
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0041 0.004
Brugia malayi A-kinase anchor protein 10, precursor 0.0043 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0022
Brugia malayi Thioredoxin family protein 0.0291 0.0741 0.074
Schistosoma mansoni cathepsin D (A01 family) 0.0125 0.0288 0.0287
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0225 0.0224
Brugia malayi beta-lactamase family protein 0.0039 0.0052 0.0051
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.001 0.0009
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0993 0.2663 0.4085
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0214 0.0213
Leishmania major C-8 sterol isomerase-like protein 0.0365 0.0943 0.1446
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0052 0.0184
Onchocerca volvulus 0.0102 0.0225 0.0331
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2647 0.7189 0.7188
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0185 0.0494
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.0342 0.0341
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0029 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0257 0.0256
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0055 0.007
Schistosoma mansoni peroxidasin 0.032 0.0819 0.0819
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0028
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0166
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Mycobacterium tuberculosis Hypothetical protein 0.0291 0.0741 0.131
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.003 0.0026 0.0084
Schistosoma mansoni rab 0.0158 0.0377 0.0376
Echinococcus granulosus endothelin converting enzyme 1 0.0102 0.0224 0.0223
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0184 0.0448 0.0447
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.0056 0.0099 0.0098
Echinococcus multilocularis caspase 2 0.0182 0.0443 0.0442
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.004 0.0054 0.0081
Brugia malayi hypothetical protein 0.023 0.0575 0.0574
Echinococcus multilocularis geminin 0.0174 0.0422 0.0421
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Entamoeba histolytica hypothetical protein 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0022
Mycobacterium leprae Conserved hypothetical protein 0.0291 0.0741 0.2709
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.001 0.0009
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0168
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.0054 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.001 0.0009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.2662
Giardia lamblia Sirtuin type 2 0.0032 0.0032 0.0084
Trypanosoma brucei trypanothione reductase 0.0057 0.0101 0.0154
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.004 0.0054 0.0081
Brugia malayi prolyl oligopeptidase family protein 0.0915 0.245 0.2449
Trichomonas vaginalis calcium binding protein, putative 0.0158 0.0377 0.101
Loa Loa (eye worm) fibroinase 0.1381 0.3724 0.3723
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0339 0.0872 0.0871
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0027 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.023 0.0575 0.0574
Onchocerca volvulus 0.0031 0.0029 0.003
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.016 0.0381 0.038
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0158 0.0378 0.1013
Trypanosoma brucei calmodulin, putative 0.0158 0.0377 0.0577
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Plasmodium falciparum serine repeat antigen 9 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.0182 0.0443 0.0442
Onchocerca volvulus Putative cubilin 0.0026 0.0016 0.001
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0063 0.0062
Echinococcus multilocularis peroxidasin 0.032 0.0819 0.0819
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.009 0.0191 0.051
Echinococcus granulosus proteasome subunit beta t family 0.004 0.0054 0.0053
Schistosoma mansoni notch 0.0026 0.0016 0.0015
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0166
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0041 0.0062
Loa Loa (eye worm) hypothetical protein 0.0039 0.0052 0.0051
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0059 0.0157
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.0342 0.0341
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.0741 0.131
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.032 0.0858
Trichomonas vaginalis calpain, putative 0.0293 0.0745 0.2
Loa Loa (eye worm) hypothetical protein 0.1654 0.447 0.447
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.009 0.0191 0.019
Trichomonas vaginalis centrin, putative 0.0158 0.0377 0.101
Trypanosoma cruzi pyruvate kinase 2, putative 0.004 0.0055 0.0054
Brugia malayi hypothetical protein 0.0502 0.1317 0.1316
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0152 0.0361 0.0967
Leishmania major hypothetical protein, conserved 0.0039 0.0052 0.0079
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0022 0.0057
Schistosoma mansoni nuclear hormone receptor 0.0024 0.001 0.0009
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0043 0.0063 0.0062
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0032 0.0031
Plasmodium vivax histone deacetylase, putative 0.0099 0.0214 0.0573
Brugia malayi calpain 5 0.0293 0.0745 0.0745
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1065 0.2858 0.2857
Echinococcus granulosus calmodulin 0.0158 0.0377 0.0376
Schistosoma mansoni hypothetical protein 0.016 0.0381 0.038
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0032 0.0083
Schistosoma mansoni hypothetical protein 0.0158 0.0377 0.0376
Plasmodium vivax glutathione reductase, putative 0.0057 0.0101 0.0269
Plasmodium vivax histone deacetylase 2, putative 0.0099 0.0214 0.0573
Brugia malayi Papain family cysteine protease containing protein 0.0339 0.0872 0.0871
Plasmodium vivax centrin-1, putative 0.0158 0.0377 0.101
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.0054 0.0142
Onchocerca volvulus 0.0184 0.0448 0.0673
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Plasmodium vivax vivapain-1 0.0761 0.2028 0.5446
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.0032 0.0084
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0063 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.0166
Schistosoma mansoni hypothetical protein 0.0184 0.0448 0.0447
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0422 0.1101 0.11
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0064 0.0063
Echinococcus multilocularis expressed protein 0.0841 0.2247 0.2246
Trichomonas vaginalis calpain, putative 0.0293 0.0745 0.2
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Brugia malayi Trypsin family protein 0.016 0.0381 0.038
Plasmodium falciparum peptidase, putative 0.0315 0.0808 0.2167
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.1381 0.3724 0.3723
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Trichomonas vaginalis calcium binding protein, putative 0.0158 0.0377 0.101
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.001 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.0342 0.0341
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Brugia malayi notch-like transmembrane receptor 0.0026 0.0016 0.0015
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0185 0.0184
Schistosoma mansoni gabp alpha 0.0072 0.0141 0.014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.001 0.0009
Echinococcus granulosus protein jagged 1 0.0026 0.0016 0.0015
Echinococcus multilocularis apoptotic protease activating factor 1 0.0138 0.0321 0.032
Giardia lamblia Cathepsin L-like protease 0.0339 0.0872 0.2359
Echinococcus granulosus proteasome subunit alpha type 6 0.004 0.0054 0.0053
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0315 0.0808 0.1238
Leishmania major calpain family cysteine protease-like protein 0.0293 0.0745 0.1143
Trypanosoma brucei centrin-3 0.0162 0.0387 0.0593
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Giardia lamblia Kinase, PLK 0.0114 0.0257 0.0693
Toxoplasma gondii aspartyl protease ASP1 0.0031 0.003 0.0045
Plasmodium falciparum proteasome subunit beta type-6, putative 0.004 0.0054 0.0142
Brugia malayi cathepsin L-like precursor 0.0959 0.2568 0.2567
Plasmodium falciparum serine repeat antigen 2 0.0339 0.0872 0.2341
Brugia malayi RNA, U transporter 1 0.0079 0.0162 0.0161
Onchocerca volvulus 0.016 0.0381 0.0571
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.0166
Trypanosoma brucei histone deacetylase 3 0.0099 0.0214 0.0327
Schistosoma mansoni axis inhibition protein axin 0.0043 0.0063 0.0062
Echinococcus multilocularis glycogen phosphorylase 0.0118 0.0269 0.0268
Brugia malayi carbohydrate phosphorylase 0.0118 0.0269 0.0268
Echinococcus granulosus EF HAND 1 calcium binding site 0.0158 0.0377 0.0376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0063 0.0062
Onchocerca volvulus Glycogen phosphorylase homolog 0.0118 0.0269 0.0398
Plasmodium falciparum plasmepsin IX 0.0112 0.0251 0.0672
Echinococcus granulosus chromatin regulatory protein sir2 0.0124 0.0284 0.0283
Echinococcus granulosus histone lysine methyltransferase setb 0.0102 0.0224 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0175
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0026 0.0016 0.001
Leishmania major hypothetical protein, conserved 0.0158 0.0377 0.0577
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0054 0.0053
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0101 0.01
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0158 0.0377 0.0376
Echinococcus granulosus Mastin 0.016 0.0381 0.038
Giardia lamblia Encystation-specific protease 0.0339 0.0872 0.2359
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0315 0.0808 0.2167
Echinococcus multilocularis histone deacetylase 0.0099 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0184 0.0448 0.0447
Leishmania major proteasome beta 2 subunit, putative 0.009 0.0191 0.0291
Entamoeba histolytica cysteine proteinase, putative 0.1381 0.3724 1
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0151 0.015
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.004 0.0054 0.0081
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0191 0.051
Trypanosoma brucei metacaspase MCA2 0.0044 0.0066 0.01
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.001 0.0009
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0032 0.0083
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0022
Loa Loa (eye worm) proteasome subunit alpha type 1 0.004 0.0054 0.0053
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0031 0.003 0.0045
Schistosoma mansoni reticulocalbin 0.0161 0.0384 0.0383
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0022 0.0706
Brugia malayi calpain family protein 1 0.2647 0.7189 0.7188
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Echinococcus multilocularis hypothetical protein 0.0993 0.2663 0.2662
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0077 0.0156 0.0155
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0315 0.0808 0.1238
Echinococcus granulosus Proteasome subunit alpha beta 0.004 0.0054 0.0053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.001 0.0009
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0054 0.0053
Schistosoma mansoni hypothetical protein 0.0027 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0075 0.0151 0.015
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.0257 0.038
Echinococcus granulosus calpain 0.0993 0.2663 0.2662
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0052 0.0092
Echinococcus multilocularis Transglutaminase 0.0291 0.0741 0.074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0059 0.0058
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0185 0.0184
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.0054 0.0142
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0654 0.1735 0.1735
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0065
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0029 0.0043
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.0054 0.0053
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0056 0.015
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0052 0.0184
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.2662
Loa Loa (eye worm) peptidase family M13 containing protein 0.0075 0.0151 0.015
Echinococcus multilocularis calmodulin 0.0158 0.0377 0.0376
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0339 0.0872 0.0871
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Loa Loa (eye worm) proteasome subunit beta type 1 0.0142 0.0333 0.0332
Echinococcus multilocularis cysteine protease 0.1381 0.3724 0.3723
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0137 0.032 0.032
Entamoeba histolytica cysteine proteinase, putative 0.0761 0.2028 0.5446
Trypanosoma brucei Metacaspase-4 0.0044 0.0066 0.01
Echinococcus granulosus neurocalcin 0.0158 0.0377 0.0376
Giardia lamblia 20S proteasome alpha subunit 5 0.004 0.0054 0.0143
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0022
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0029 0.0043
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0257 0.0256
Loa Loa (eye worm) hypothetical protein 0.0339 0.0872 0.0871
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0184 0.0448 0.0447
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0063 0.0062
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0032 0.0048
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0023 0.0059
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0041 0.0108
Echinococcus granulosus citrate lyase subunit beta protein 0.003 0.0026 0.0025
Echinococcus multilocularis Glycosyl transferase, family 35 0.0118 0.0269 0.0268
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0041 0.004
Toxoplasma gondii hypothetical protein 0.0031 0.0029 0.0043
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0158 0.0378 0.0377
Trypanosoma cruzi cysteine protease, putative 0.0761 0.2028 0.2028
Plasmodium vivax calpain, putative 0.0993 0.2663 0.715
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.004 0.0054 0.0081
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0031 0.003 0.0029
Onchocerca volvulus Cell death protein 3 homolog 0.0182 0.0443 0.0665
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0041 0.0062
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.001 0.0009
Plasmodium falciparum serine repeat antigen 3 0.0339 0.0872 0.2341
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0052 0.0092
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Plasmodium falciparum importin beta, putative 0.0028 0.0021 0.0054
Echinococcus multilocularis endothelin converting enzyme 1 0.0102 0.0224 0.0223
Plasmodium falciparum pyruvate kinase 0.004 0.0055 0.0145
Trypanosoma brucei cysteine peptidase C (CPC) 0.1371 0.3695 0.567
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.4085
Onchocerca volvulus 0.0291 0.0741 0.1124
Leishmania major histone deacetylase, putative 0.0088 0.0185 0.0282
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Toxoplasma gondii EF hand domain-containing protein 0.0158 0.0377 0.0577
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.0257 0.0256
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.001 0.0009
Echinococcus multilocularis acylamino acid releasing enzyme 0.0315 0.0808 0.0807
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0063 0.0062
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0028
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0339 0.0872 0.0871
Brugia malayi gamma-secretase subunit aph-1 0.0267 0.0676 0.0675
Echinococcus granulosus delta-like protein 1 0.0026 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0059 0.0157
Onchocerca volvulus Deterin homolog 0.0184 0.0448 0.0673
Loa Loa (eye worm) hypothetical protein 0.0051 0.0083 0.0082
Echinococcus multilocularis proteasome (prosome, macropain) 0.0247 0.0619 0.0618
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0099 0.0264
Onchocerca volvulus 0.016 0.0381 0.0571
Brugia malayi transcriptional regulator, Sir2 family protein 0.0124 0.0284 0.0283
Plasmodium falciparum proteasome subunit beta type-3, putative 0.004 0.0054 0.0142
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1381 0.3724 1
Brugia malayi hypothetical protein 0.016 0.0381 0.038
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.0054 0.0142
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0059 0.0058
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0124 0.0284 0.0283
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0051 0.0085 0.0305
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.0341 0.0603
Echinococcus granulosus flap endonuclease 1 0.0028 0.0021 0.0021
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0161 0.0384 0.0383
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0993 0.2663 0.2662
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0032 0.0031
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0284 0.0283
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0023 0.0074
Onchocerca volvulus 0.1381 0.3724 0.5708
Brugia malayi Kringle domain containing protein 0.0048 0.0075 0.0074
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0161 0.0384 0.0383
Loa Loa (eye worm) hypothetical protein 0.0048 0.0075 0.0074
Plasmodium falciparum plasmepsin X 0.0112 0.0251 0.0672
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.001 0.0009
Echinococcus granulosus Dipeptidyl peptidase 9 0.0654 0.1735 0.1735
Schistosoma mansoni calpain C (C02 family) 0.0993 0.2663 0.2662
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0761 0.2028 0.5446
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0257 0.0256
Trypanosoma brucei calpain-like protein, putative 0.0993 0.2663 0.4085
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0054 0.0053
Schistosoma mansoni notch 0.0026 0.0016 0.0015
Trypanosoma brucei calpain, putative 0.0293 0.0745 0.1143
Entamoeba histolytica cysteine proteinase 2 0.0761 0.2028 0.5446
Loa Loa (eye worm) trypsin family protein 0.016 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Entamoeba histolytica cysteine proteinase, putative 0.0959 0.2568 0.6895
Leishmania major centrin, putative 0.0158 0.0377 0.0577
Brugia malayi NAD-dependent deacetylase SIRT1 0.0137 0.032 0.032
Trypanosoma brucei metacaspase 0.0044 0.0066 0.01
Brugia malayi Cytochrome P450 family protein 0.0036 0.0042 0.0041
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.004 0.0054 0.0053
Mycobacterium ulcerans hypothetical protein 0.0291 0.0741 0.276
Plasmodium vivax plasmepsin V, putative 0.0031 0.003 0.0078
Echinococcus granulosus notch 0.0026 0.0016 0.0015
Entamoeba histolytica cysteine protease, putative 0.0339 0.0872 0.2341
Brugia malayi Calmodulin-like protein 0.0158 0.0377 0.0376
Plasmodium vivax aspartyl proteinase, putative 0.0031 0.003 0.0078
Loa Loa (eye worm) hypothetical protein 0.0105 0.0233 0.0232
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0003 0.0006
Brugia malayi hypothetical protein 0.0043 0.0064 0.0063
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0052 0.0086 0.0085
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0062
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0061 0.0093
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.033 0.1223
Brugia malayi steroid hormone receptor 0.0024 0.001 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.076 0.076
Brugia malayi proteasome subunit alpha type 2 0.004 0.0054 0.0053
Giardia lamblia Proteasome subunit beta type 7 precursor 0.004 0.0054 0.0143
Schistosoma mansoni neprilysin 0.0027 0.0018 0.0017
Mycobacterium ulcerans proteasome PrcA 0.004 0.0054 0.0189
Echinococcus multilocularis calpain 7 (C02 family) 0.0993 0.2663 0.2662
Echinococcus multilocularis proteasome subunit beta type 6 0.004 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.2401 0.6516 0.6516
Echinococcus multilocularis cathepsin b 0.3674 1 1
Leishmania major histone deacetylase, putative 0.0099 0.0214 0.0327
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.001 0.0009
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0032 0.0083
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1371 0.3695 0.9924
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.0054 0.0142
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.004 0.0054 0.0053
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0055 0.007
Schistosoma mansoni caspase-3 (C14 family) 0.0118 0.0266 0.0266
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0032 0.0031
Trypanosoma brucei calmodulin, putative 0.0161 0.0384 0.0588
Brugia malayi Trypsin family protein 0.016 0.0381 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.4085
Loa Loa (eye worm) hypothetical protein 0.0293 0.0745 0.0745
Echinococcus multilocularis regulator of G protein signaling 7 0.0043 0.0063 0.0062
Trichomonas vaginalis calcium binding protein, putative 0.0162 0.0387 0.1037
Onchocerca volvulus Cathepsin L homolog 0.0339 0.0872 0.1326
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.016 0.0381 0.038
Entamoeba histolytica glycogen phosphorylase, putative 0.0118 0.0269 0.0719
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.001 0.0009
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0301 0.1052
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0041 0.0108
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.004 0.0054 0.0142
Echinococcus multilocularis calpain A 0.2808 0.7628 0.7628
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0034 0.0033
Chlamydia trachomatis pyruvate kinase 0.004 0.0055 0.1948
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.004 0.0054 0.0053
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0032 0.0031
Echinococcus multilocularis glycogen phosphorylase 0.0118 0.0269 0.0268
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0301 0.0533
Giardia lamblia Hypothetical protein 0.0161 0.0384 0.1038
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0059 0.0157
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0745 0.0745
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0365 0.0943 0.0942
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0021 0.0056
Plasmodium vivax proteasome subunit beta type-5, putative 0.0247 0.0619 0.1661
Echinococcus multilocularis tissue type plasminogen activator 0.0048 0.0075 0.0074
Brugia malayi ecdysteroid receptor 0.0024 0.001 0.0009
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.004 0.0054 0.0053
Brugia malayi prolyl oligopeptidase family protein 0.0315 0.0808 0.0807
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.004 0.0054 0.0053
Loa Loa (eye worm) calpain family protein 1 0.1946 0.5271 0.5271
Trypanosoma brucei proteasome subunit beta type-2, putative 0.009 0.0191 0.0291
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0293 0.0745 0.2
Plasmodium falciparum plasmepsin IV 0.0031 0.003 0.0078
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0185 0.0282
Onchocerca volvulus 0.0158 0.0377 0.0564
Echinococcus granulosus cathepsin l cysteine peptidase 0.1381 0.3724 0.3723
Trichomonas vaginalis myosin light chain 1, putative 0.0158 0.0377 0.101
Onchocerca volvulus 0.0026 0.0016 0.001
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0185 0.0494
Onchocerca volvulus 0.0339 0.0872 0.1326
Onchocerca volvulus 0.0158 0.0377 0.0564
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0066 0.0065
Echinococcus multilocularis cathepsin b 0.3674 1 1
Echinococcus multilocularis cysteine protease 0.1381 0.3724 0.3723
Trypanosoma cruzi oligopeptidase b 0.0998 0.2675 0.2674
Onchocerca volvulus 0.0959 0.2568 0.3932
Trichomonas vaginalis conserved hypothetical protein 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.0102 0.0224 0.0223
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0339 0.0872 0.2341
Brugia malayi cathepsin L-like cysteine proteinase 0.0339 0.0872 0.0871
Entamoeba histolytica cysteine protease, putative 0.0339 0.0872 0.2341
Plasmodium vivax proteasome subunit alpha type-3, putative 0.004 0.0054 0.0142
Trypanosoma cruzi cysteine proteinase, putative 0.0761 0.2028 0.2028
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0118 0.0266 0.0266
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0267 0.0676 0.0675
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Schistosoma mansoni calmodulin 0.0158 0.0377 0.0376
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.0054 0.0053
Plasmodium falciparum proteasome subunit beta type-7, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) calpain 0.0993 0.2663 0.2662
Echinococcus granulosus cpg binding protein 0.0035 0.0039 0.0038
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0021 0.0055
Loa Loa (eye worm) hypothetical protein 0.0365 0.0943 0.0942
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.004 0.0054 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Toxoplasma gondii cathepsin CPC2 0.0339 0.0872 0.1337
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0059 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.1487 0.4014 0.4013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0145 0.0144
Brugia malayi Cathepsin L-like precursor 0.0959 0.2568 0.2567
Schistosoma mansoni cell polarity protein 0.0026 0.0016 0.0015
Toxoplasma gondii EFHC1, putative 0.0158 0.0377 0.0577
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0032 0.0083
Trypanosoma brucei hypothetical protein 0.0293 0.0745 0.1143
Echinococcus multilocularis chromatin regulatory protein sir2 0.0124 0.0284 0.0283
Entamoeba histolytica hypothetical protein 0.0043 0.0064 0.0168
Plasmodium falciparum metacaspase-like protein 0.0044 0.0066 0.0175
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0021 0.0032
Brugia malayi 20S proteasome alpha5 subunit 0.004 0.0054 0.0053
Giardia lamblia Cathepsin L precursor 0.0339 0.0872 0.2359
Entamoeba histolytica calcium binding family protein 0.0158 0.0377 0.101
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.0301 0.0533
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0185 0.0494
Brugia malayi Ets-domain containing protein 0.0072 0.0141 0.014
Brugia malayi Delta serrate ligand family protein 0.0026 0.0016 0.0015
Trichomonas vaginalis calmodulin-2, putative 0.0158 0.0377 0.101
Mycobacterium ulcerans hypothetical protein 0.003 0.0026 0.0084
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0158 0.0377 0.101
Trichomonas vaginalis conserved hypothetical protein 0.0293 0.0745 0.2
Onchocerca volvulus 0.1381 0.3724 0.5708
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0064 0.0063
Mycobacterium tuberculosis Conserved protein 0.0039 0.0052 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0099 0.0264
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0063 0.0062
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0224 0.0223
Brugia malayi proteasome subunit alpha type 4 0.004 0.0054 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Plasmodium falciparum flap endonuclease 1 0.0028 0.0021 0.0055
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0029 0.0043
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0284 0.0283
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.004 0.0054 0.0142
Echinococcus multilocularis Mastin 0.016 0.0381 0.038
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.016 0.0381 0.038
Toxoplasma gondii cathepsin CPL 0.1381 0.3724 0.5714
Trypanosoma cruzi oligopeptidase b 0.0998 0.2675 0.2674
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0058
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0052 0.0051
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0301 0.0533
Leishmania major calmodulin-like protein 0.0158 0.0377 0.0577
Echinococcus multilocularis regulator of G protein signaling 3 0.0043 0.0063 0.0062
Trichomonas vaginalis calcium binding proteins, putative 0.0158 0.0377 0.101
Entamoeba histolytica cysteine protease, putative 0.0339 0.0872 0.2341
Echinococcus multilocularis Proteasome, subunit alpha beta 0.004 0.0054 0.0053
Leishmania major proteasome beta-1 subunit, putative 0.004 0.0054 0.0081
Echinococcus granulosus cathepsin l1 0.1381 0.3724 0.3723
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0339 0.0872 0.2341
Giardia lamblia Pyruvate kinase 0.004 0.0055 0.0146
Brugia malayi Papain family cysteine protease containing protein 0.0761 0.2028 0.2028
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0141 0.033 0.0505
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0184 0.0448 0.0447
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0339 0.0872 0.2341
Trypanosoma brucei Calpain-like protein 2 0.0293 0.0745 0.1143
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.004 0.0054 0.0142
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0022 0.0032
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0041 0.0108
Trypanosoma brucei centrin, putative 0.0158 0.0377 0.0577
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Toxoplasma gondii peptidase family M13 protein 0.0102 0.0224 0.0343
Brugia malayi Animal haem peroxidase family protein 0.032 0.0819 0.0819
Schistosoma mansoni hypothetical protein 0.0027 0.0018 0.0017
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0247 0.0619 0.0618
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0016 0.0015
Leishmania major cysteine peptidase A (CPA) 0.1381 0.3724 0.5714
Loa Loa (eye worm) hypothetical protein 0.0339 0.0872 0.0871
Onchocerca volvulus 0.0806 0.2149 0.3289
Onchocerca volvulus 0.0031 0.0029 0.003
Schistosoma mansoni regulator of G protein signaling 0.0043 0.0063 0.0062
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0158 0.0377 0.0577
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0066 0.0175
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0059 0.0058
Brugia malayi proteasome subunit alpha type 1 0.004 0.0054 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0648 0.0647
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.001 0.0009
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.001 0.0009
Onchocerca volvulus 0.1381 0.3724 0.5708
Loa Loa (eye worm) animal heme peroxidase 0.032 0.0819 0.0819
Echinococcus multilocularis calpain 5 0.0993 0.2663 0.2662
Brugia malayi beta-lactamase 0.0039 0.0052 0.0051
Leishmania major cathepsin L-like protease 0.1381 0.3724 0.5714
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi peptidase family M13 containing protein 0.0025 0.0013 0.0012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.004 0.0054 0.0053
Echinococcus granulosus histone deacetylase 6 0.0099 0.0214 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Giardia lamblia Cathepsin B precursor 0.0339 0.0872 0.2359
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0042 0.0041
Mycobacterium tuberculosis Conserved hypothetical protein 0.0291 0.0741 0.131
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Toxoplasma gondii exonuclease III APE 0.0041 0.0056 0.0085
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0142 0.0333 0.0332
Onchocerca volvulus 0.0031 0.0029 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0339 0.0872 0.2341
Trichomonas vaginalis calcineurin B subunit, putative 0.0158 0.0377 0.101
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0339 0.0872 0.2341
Loa Loa (eye worm) hypothetical protein 0.0339 0.0872 0.0871
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0761 0.2028 0.5446
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.0042 0.0041
Loa Loa (eye worm) ctsf protein 0.1381 0.3724 0.3723
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0054 0.0081
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0102 0.0224 0.0223
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0031 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0339 0.0872 0.0871
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2805 0.7621 0.7621
Trypanosoma cruzi major cysteine proteinase, putative 0.0339 0.0872 0.0871
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0059 0.0058
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.0341 0.1202
Echinococcus multilocularis transmembrane protease serine 3 0.016 0.0381 0.038
Schistosoma mansoni hypothetical protein 0.0043 0.0064 0.0063
Mycobacterium ulcerans hypothetical protein 0.0291 0.0741 0.276
Trichomonas vaginalis centrin, putative 0.0158 0.0377 0.101
Onchocerca volvulus Prolyl endopeptidase homolog 0.2401 0.6516 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0896 0.2396 0.2396
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.004 0.0055 0.0097
Onchocerca volvulus Notchless protein homolog 0.004 0.0054 0.0068
Echinococcus multilocularis gamma secretase subunit aph 1 0.0267 0.0676 0.0675
Brugia malayi Cathepsin L-like precursor 0.0422 0.1101 0.11
Trypanosoma brucei prolyl endopeptidase 0.2401 0.6516 1
Mycobacterium leprae Probable pyruvate kinase PykA 0.004 0.0055 0.0124
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.001 0.0009
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0293 0.0745 0.1143
Plasmodium vivax vivapain-3 0.0761 0.2028 0.5446
Mycobacterium ulcerans zinc metalloprotease 0.0102 0.0224 0.0827
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0142 0.0333 0.0332
Trypanosoma brucei hypothetical protein, conserved 0.0158 0.0377 0.0577
Plasmodium falciparum thioredoxin reductase 0.0057 0.0101 0.0269
Giardia lamblia Cathepsin B precursor 0.1371 0.3695 1
Trypanosoma cruzi cysteine peptidase, putative 0.0422 0.1101 0.11
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0062
Giardia lamblia Alanyl dipeptidyl peptidase 0.0315 0.0808 0.2184
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0023 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Schistosoma mansoni neprilysin-2 (M13 family) 0.0052 0.0086 0.0085
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0377 0.101
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0031 0.003 0.0029
Schistosoma mansoni hypothetical protein 0.0466 0.122 0.1219
Onchocerca volvulus 0.0039 0.0052 0.0066
Echinococcus multilocularis caspase 8 0.0044 0.0066 0.0065
Echinococcus multilocularis inhibitor of apoptosis protein 0.0184 0.0448 0.0447
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0185 0.0494
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0026 0.0084
Trypanosoma cruzi calmodulin, putative 0.0158 0.0377 0.0376
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0761 0.2028 0.2028
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0293 0.0745 0.2
Toxoplasma gondii peptidase, T1 family protein 0.004 0.0054 0.0081
Echinococcus granulosus glycoprotein Antigen 5 0.016 0.0381 0.038
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Giardia lamblia Transglutaminase/protease, putative 0.0291 0.0741 0.2002
Schistosoma mansoni aldehyde dehydrogenase 0.0141 0.033 0.0329
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0041 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Leishmania major cathepsin L-like protease 0.1381 0.3724 0.5714
Trypanosoma brucei pyruvate kinase 1 0.004 0.0055 0.0083
Mycobacterium tuberculosis Probable reductase 0.013 0.0301 0.0533
Loa Loa (eye worm) hypothetical protein 0.0959 0.2568 0.2567
Loa Loa (eye worm) hypothetical protein 0.0184 0.0448 0.0447
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.0257 0.0256
Schistosoma mansoni cpg binding protein 0.0035 0.0039 0.0038
Echinococcus multilocularis histone deacetylase 8 0.0042 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Leishmania major proteasome beta 5 subunit, putative 0.0247 0.0619 0.0949
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0339 0.0872 0.2341
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0025 0.0013 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.033 0.1223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0998 0.2675 1
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0185 0.0494
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0059 0.0058
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0085 0.0225
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0339 0.0872 0.2341
Echinococcus granulosus EF hand domain containing family member A2 0.0161 0.0384 0.0383
Entamoeba histolytica cysteine protease, putative 0.1381 0.3724 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0028
Leishmania major hypothetical protein, conserved 0.0048 0.0075 0.0114
Schistosoma mansoni mitochondrial solute carrier 0.0158 0.0377 0.0376
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0023 0.0074
Mycobacterium ulcerans hypothetical protein 0.0039 0.0052 0.0184
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0013 0.0012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0708 0.1881 0.1881
Loa Loa (eye worm) RGS-3 protein 0.0043 0.0063 0.0062
Schistosoma mansoni hemoglobinase (C13 family) 0.0152 0.0361 0.036
Schistosoma mansoni notch 0.0026 0.0016 0.0015
Leishmania major hypothetical protein, unknown function 0.0293 0.0745 0.1143
Schistosoma mansoni chromatin regulatory protein sir2 0.0124 0.0284 0.0283
Trypanosoma cruzi cysteine peptidase, putative 0.0761 0.2028 0.2028
Giardia lamblia Cathepsin L precursor 0.0339 0.0872 0.2359
Echinococcus granulosus dnaJ subfamily B 0.0466 0.122 0.1219
Echinococcus granulosus proteasome subunit alpha type 2 0.004 0.0054 0.0053
Leishmania major calpain protease-like protein 0.0293 0.0745 0.1143
Toxoplasma gondii troponin c, isotype gamma, putative 0.0158 0.0377 0.0577
Loa Loa (eye worm) hypothetical protein 0.0044 0.0066 0.0065
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0293 0.0745 0.1143
Giardia lamblia Cathepsin L-like protease 0.0339 0.0872 0.2359
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0062
Echinococcus granulosus centrin 2 0.0158 0.0377 0.0376
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0054 0.0081
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1381 0.3724 0.3723
Plasmodium falciparum serine repeat antigen 6 0.0339 0.0872 0.2341
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Trypanosoma cruzi hypothetical protein, conserved 0.0315 0.0808 0.0807
Brugia malayi hypothetical protein 0.0031 0.003 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0339 0.0872 0.2341
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0066 0.0065
Entamoeba histolytica cysteine proteinase, putative 0.0761 0.2028 0.5446
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.001 0.0009
Giardia lamblia Cysteine protease 0.0339 0.0872 0.2359
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0993 0.2663 0.2662
Brugia malayi cathepsin Z-like cysteine proteinase 0.0339 0.0872 0.0871
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0339 0.0872 0.0871
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.001 0.0009
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0142 0.0333 0.0891
Entamoeba histolytica cysteine proteinase, putative 0.0761 0.2028 0.5446
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0118 0.0266 0.0266
Brugia malayi Cadherin domain containing protein 0.0026 0.0016 0.0015
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0654 0.1735 0.2662
Onchocerca volvulus 0.0031 0.0029 0.003
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0185 0.0494
Schistosoma mansoni hypothetical protein 0.0298 0.076 0.076
Brugia malayi cathepsin F-like cysteine proteinase 0.0339 0.0872 0.0871
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.004 0.0054 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.001 0.0009
Echinococcus granulosus protein jagged 2 0.0026 0.0016 0.0015
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0214 0.0213
Leishmania major oligopeptidase b 0.0998 0.2675 0.4104
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.004 0.0054 0.0081
Toxoplasma gondii microneme protein MIC4 0.0031 0.0029 0.0043
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.0219 0.0219
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Echinococcus multilocularis prolyl endopeptidase 0.2401 0.6516 0.6516
Onchocerca volvulus 0.016 0.0381 0.0571
Schistosoma mansoni ap endonuclease 0.0041 0.0056 0.0056
Echinococcus multilocularis axis inhibition protein axin 0.0043 0.0063 0.0062
Echinococcus granulosus histone deacetylase 6 0.0105 0.0231 0.023
Brugia malayi Trypsin-like protease protein 5 0.016 0.0381 0.038
Brugia malayi MH2 domain containing protein 0.0128 0.0295 0.0294
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.016 0.0381 0.038
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Trypanosoma brucei caltractin, putative 0.0162 0.0387 0.0593
Leishmania major programmed cell death 6 protein-like protein 0.0158 0.0377 0.0577
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Loa Loa (eye worm) hypothetical protein 0.0088 0.0185 0.0184
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0052 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0024 0.001 0.0009
Loa Loa (eye worm) calpain D 0.0293 0.0745 0.0745
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) beta-lactamase 0.0039 0.0052 0.0051
Plasmodium falciparum proteasome subunit beta type-2, putative 0.009 0.0191 0.051
Loa Loa (eye worm) aspartyl protease 6 0.0031 0.003 0.0029
Echinococcus granulosus neurogenic locus protein delta 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.0166
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.004 0.0054 0.0053
Plasmodium falciparum centrin-1 0.0158 0.0377 0.101
Leishmania major histone deacetylase, putative 0.0099 0.0214 0.0327
Giardia lamblia 20S proteasome alpha subunit 6 0.004 0.0054 0.0143
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.004 0.0054 0.0081
Brugia malayi Cathepsin L-like precursor 0.1381 0.3724 0.3723
Schistosoma mansoni cathepsin F (C01 family) 0.0959 0.2568 0.2567
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0052 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Trypanosoma cruzi hypothetical protein, conserved 0.0315 0.0808 0.0807
Loa Loa (eye worm) pyruvate kinase 0.004 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0021
Brugia malayi calpain family protein 1 0.2647 0.7189 0.7188
Entamoeba histolytica glycogenphosphorylase, putative 0.0051 0.0085 0.0225
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0021 0.0032
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0052 0.0138
Loa Loa (eye worm) cathepsin B 0.1371 0.3695 0.3695
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0029
Brugia malayi nuclear hormone receptor 0.0024 0.001 0.0009
Plasmodium vivax serine-repeat antigen (SERA) 0.0339 0.0872 0.2341
Echinococcus multilocularis EF hand domain containing family member A2 0.0158 0.0377 0.0376
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Trypanosoma brucei ATP-dependent protease subunit HslV 0.004 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0077 0.0156 0.0155
Leishmania major metacaspase, putative 0.0044 0.0066 0.01
Echinococcus granulosus pyruvate kinase 0.004 0.0055 0.0054
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Echinococcus granulosus cathepsin L cysteine proteinase 0.1381 0.3724 0.3723
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Plasmodium vivax histone deacetylase, putative 0.0042 0.006 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0023 0.0074
Loa Loa (eye worm) pyruvate kinase 0.004 0.0055 0.0054
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.004 0.0055 0.0145
Giardia lamblia Cysteine protease 0.0339 0.0872 0.2359
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0002
Leishmania major calmodulin-like protein 0.0158 0.0377 0.0577
Loa Loa (eye worm) hypothetical protein 0.0035 0.0041 0.004
Loa Loa (eye worm) animal heme peroxidase 0.032 0.0819 0.0819
Schistosoma mansoni ap endonuclease 0.0041 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Echinococcus multilocularis caspase 0.0118 0.0266 0.0266
Plasmodium falciparum plasmepsin VIII, putative 0.0031 0.003 0.0078
Onchocerca volvulus 0.0026 0.0016 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0293 0.0745 0.2
Brugia malayi Cathepsin L-like precursor 0.1381 0.3724 0.3723
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0059 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Trypanosoma brucei Aph-1 protein, putative 0.0104 0.023 0.0351
Brugia malayi Pepsin A precursor 0.0031 0.003 0.0029
Plasmodium falciparum metacaspase 1 0.0044 0.0066 0.0175
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.004 0.0054 0.0053
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1381 0.3724 1
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0247 0.0619 0.2252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0342 0.0341
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.4085
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0185 0.0184
Brugia malayi proteasome subunit beta type 1 0.0142 0.0333 0.0332
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Giardia lamblia Hypothetical protein 0.0291 0.0741 0.2002
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0247 0.0619 0.1661
Echinococcus multilocularis cathepsin L cysteine protease 0.1381 0.3724 0.3723
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Brugia malayi proteasome subunit alpha type 6 0.004 0.0054 0.0053
Brugia malayi hypothetical protein 0.0031 0.003 0.0029
Brugia malayi Histone deacetylase 1 0.0088 0.0185 0.0184
Schistosoma mansoni peroxidasin 0.032 0.0819 0.0819
Toxoplasma gondii cathepsin CPC1 0.0339 0.0872 0.1337
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1381 0.3724 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0141 0.033 0.0329
Trichomonas vaginalis hypothetical protein 0.0293 0.0745 0.2
Brugia malayi Ets-domain containing protein 0.0072 0.0141 0.014
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0106 0.0105
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0032 0.0083
Brugia malayi aspartic protease BmAsp-1, identical 0.0031 0.003 0.0029
Leishmania major cathepsin L-like protease 0.1381 0.3724 0.5714
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0158 0.0378 0.0579
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Echinococcus granulosus axis inhibition protein axin 0.0043 0.0063 0.0062
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Onchocerca volvulus 0.0039 0.0052 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0063 0.0166
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0058
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.016 0.0381 0.038
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0546 0.1438 0.2205
Loa Loa (eye worm) hypothetical protein 0.0102 0.0224 0.0223
Echinococcus multilocularis proteasome subunit beta type 7 0.004 0.0054 0.0053
Echinococcus granulosus histone deacetylase 0.0099 0.0214 0.0213
Mycobacterium ulcerans beta-lactamase 0.0039 0.0052 0.0184
Echinococcus granulosus peroxidasin 0.032 0.0819 0.0819
Plasmodium vivax proteasome subunit alpha type-2, putative 0.004 0.0054 0.0142
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0023 0.0074
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.001 0.0009
Giardia lamblia Cathepsin L precursor 0.0339 0.0872 0.2359
Loa Loa (eye worm) calpain 5 0.0701 0.1862 0.1861
Trypanosoma brucei I/6 autoantigen 0.0158 0.0377 0.0577
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.004 0.0054 0.0081
Onchocerca volvulus 0.0026 0.0016 0.001
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0247 0.0619 0.0949
Loa Loa (eye worm) programmed cell death protein 6 0.0161 0.0384 0.0383
Toxoplasma gondii EGF family domain-containing protein 0.0026 0.0016 0.0023
Leishmania major proteasome alpha 2 subunit, putative 0.004 0.0054 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.0342 0.0341
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0022
Echinococcus multilocularis histone deacetylase 7 0.0099 0.0214 0.0213
Loa Loa (eye worm) CYP4Cod1 0.0036 0.0042 0.0041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0993 0.2663 0.2662
Brugia malayi Thioredoxin reductase 0.0057 0.0101 0.01
Onchocerca volvulus Pyruvate kinase homolog 0.004 0.0055 0.007
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0054
Trichomonas vaginalis esterase, putative 0.0039 0.0052 0.0138
Toxoplasma gondii preprocathepsin c precursor, putative 0.0339 0.0872 0.1337
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0052 0.0051
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0137 0.032 0.032
Echinococcus multilocularis neural cadherin 0.0026 0.0016 0.0015
Trypanosoma cruzi 20S proteasome subunit 0.009 0.0191 0.019
Schistosoma mansoni histone deacetylase 0.0088 0.0185 0.0184
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0054 0.0053
Brugia malayi hypothetical protein 0.0043 0.0063 0.0062
Brugia malayi Trypsin family protein 0.016 0.0381 0.038
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1381 0.3724 1
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0185 0.0494
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0044 0.0064 0.0063
Mycobacterium ulcerans proteasome PrcB 0.0247 0.0619 0.2306
Entamoeba histolytica protein kinase, putative 0.0701 0.1863 0.5001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0339 0.0872 0.2341
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0339 0.0872 0.2341
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.004 0.0054 0.0053
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0052 0.0051
Echinococcus multilocularis protein jagged 1 0.0026 0.0016 0.0015
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0191 0.051
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0339 0.0872 0.2341
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0339 0.0872 0.0871
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0032 0.0083
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0032 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0959 0.2568 0.6895
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.001 0.0009
Trypanosoma brucei kinesin, putative 0.0701 0.1862 0.2856
Brugia malayi Cathepsin L-like precursor 0.1381 0.3724 0.3723
Plasmodium falciparum cysteine proteinase falcipain 1 0.0761 0.2028 0.5446
Echinococcus multilocularis pyruvate kinase 0.004 0.0055 0.0054
Schistosoma mansoni histone deacetylase hda2 0.0105 0.0231 0.023
Brugia malayi Cathepsin L-like precursor 0.0959 0.2568 0.2567
Plasmodium vivax metacaspase 1, putative 0.0044 0.0066 0.0175
Giardia lamblia Histone deacetylase 0.0088 0.0185 0.0497
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.3674 1 1
Echinococcus multilocularis calcium uptake protein 1 0.0161 0.0384 0.0383
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.006 0.006
Echinococcus multilocularis caspase 3 0.0073 0.0145 0.0144
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Entamoeba histolytica cysteine proteinase 1, putative 0.0761 0.2028 0.5446
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.0054 0.0081
Schistosoma mansoni hypothetical protein 0.0026 0.0016 0.0015
Plasmodium vivax plasmepsin IV, putative 0.0031 0.003 0.0078
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0185 0.0494
Loa Loa (eye worm) hypothetical protein 0.2354 0.6388 0.6387
Toxoplasma gondii ABC1 family protein 0.0039 0.0052 0.0079
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0142 0.0333 0.0332
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0059 0.0157
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0141 0.033 0.0329
Trypanosoma brucei polo-like protein kinase 0.0114 0.0257 0.0393
Giardia lamblia Cathepsin L precursor 0.0339 0.0872 0.2359
Schistosoma mansoni calpain-7 (C02 family) 0.0996 0.2671 0.267
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0043
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0032 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0339 0.0872 0.2341
Onchocerca volvulus 0.0029 0.0023 0.0021
Leishmania major cathepsin L-like protease 0.1381 0.3724 0.5714
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0052 0.0138
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.004 0.0054 0.0142
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Loa Loa (eye worm) hypothetical protein 0.0186 0.0455 0.0454
Loa Loa (eye worm) hypothetical protein 0.01 0.0219 0.0219
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0016 0.0015
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.013 0.0301 0.0806
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.0342 0.0341
Brugia malayi Flap endonuclease-1 0.0028 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0339 0.0872 0.2341
Onchocerca volvulus 0.0042 0.0059 0.0077
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0065
Entamoeba histolytica glycogen phosphorylase, putative 0.0118 0.0269 0.0719
Brugia malayi Animal haem peroxidase family protein 0.032 0.0819 0.0819
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0009
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0054 0.0053
Schistosoma mansoni flap endonuclease-1 0.0025 0.0014 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0185 0.0494
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0339 0.0872 0.2359
Onchocerca volvulus 0.1381 0.3724 0.5708
Onchocerca volvulus 0.016 0.0381 0.0571
Echinococcus multilocularis cathepsin L 0.0339 0.0872 0.0871
Loa Loa (eye worm) hypothetical protein 0.0422 0.1101 0.11
Entamoeba histolytica prolyl oligopeptidase family protein 0.0315 0.0808 0.2167
Entamoeba histolytica hypothetical protein 0.0043 0.0063 0.0166
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Echinococcus granulosus regulator of G protein signaling 7 0.0043 0.0063 0.0062
Toxoplasma gondii thioredoxin reductase 0.0057 0.0101 0.0154
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.0054 0.0081
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0064 0.0063
Trypanosoma brucei calpain, putative 0.0293 0.0745 0.1143
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.001 0.0009
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0915 0.245 0.2449
Schistosoma mansoni hypothetical protein 0.0293 0.0745 0.0745
Plasmodium falciparum plasmepsin V 0.0031 0.003 0.0078
Loa Loa (eye worm) cysteine protease 0.1381 0.3724 0.3723
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.0054 0.0053
Schistosoma mansoni glycogen phosphorylase 0.0118 0.0269 0.0268
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.001 0.0009
Schistosoma mansoni hypothetical protein 0.0174 0.0422 0.0421
Schistosoma mansoni cercarial elastase (S01 family) 0.016 0.0381 0.038
Plasmodium vivax aspartyl protease, putative 0.0031 0.003 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Brugia malayi EF hand family protein 0.0161 0.0384 0.0383
Brugia malayi Papain family cysteine protease containing protein 0.0339 0.0872 0.0871
Loa Loa (eye worm) prolyl oligopeptidase 0.0315 0.0808 0.0807
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi EGF-like domain containing protein 0.0026 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0066 0.0175
Plasmodium vivax proteasome subunit beta type-2, putative 0.009 0.0191 0.051
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.006 0.006
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0022 0.0057
Plasmodium vivax unspecified product 0.0339 0.0872 0.2341
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0339 0.0872 0.2341
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0007 0.0015
Trypanosoma brucei calpain-like protein, putative 0.0993 0.2663 0.4085
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0054 0.0142
Brugia malayi PXA domain containing protein 0.0043 0.0063 0.0062
Trypanosoma cruzi prolyl endopeptidase 0.2401 0.6516 0.6516
Echinococcus granulosus cathepsin l1 0.0959 0.2568 0.2567
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.004 0.0054 0.0142
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0054 0.0053
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0056 0.0199
Echinococcus granulosus neural cadherin 0.0026 0.0016 0.0015
Echinococcus granulosus Proteasome subunit alpha type 7 0.004 0.0054 0.0053
Echinococcus granulosus regulator of G protein signaling 3 0.0043 0.0063 0.0062
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0054 0.0142
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0056 0.0085
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2805 0.7621 0.7621
Giardia lamblia 20S proteasome alpha subunit 4 0.004 0.0054 0.0143
Echinococcus multilocularis centrin 2 0.0158 0.0377 0.0376
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0124 0.0284 0.0435
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.078 0.2079 0.2079
Onchocerca volvulus 0.0031 0.003 0.0031
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.004 0.0054 0.0081
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0993 0.2663 0.2662
Entamoeba histolytica calcium-binding protein, putative 0.0158 0.0377 0.101
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0022 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0257 0.0687
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0339 0.0872 0.2359
Echinococcus multilocularis calpain 0.0993 0.2663 0.2662
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.004 0.0054 0.0053
Onchocerca volvulus Peroxidase homolog 0.032 0.0819 0.1245
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0101 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0339 0.0872 0.2341
Onchocerca volvulus 0.1381 0.3724 0.5708
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0339 0.0872 0.2341
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0032 0.0031
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.0341 0.0603
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0054 0.0081
Loa Loa (eye worm) fli-1 protein 0.0218 0.0542 0.0541
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0959 0.2568 0.6895
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0032 0.0083
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Echinococcus granulosus acylamino acid releasing enzyme 0.0315 0.0808 0.0807
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0007 0.0006
Trypanosoma cruzi Aph-1 protein, putative 0.0104 0.023 0.0229
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0054 0.0053
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0293 0.0745 0.0745
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0654 0.1735 0.2662
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi PXA domain containing protein 0.0043 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Brugia malayi fibroinase precursor 0.0339 0.0872 0.0871
Loa Loa (eye worm) hypothetical protein 0.0043 0.0063 0.0062
Brugia malayi prolyl oligopeptidase family protein 0.0315 0.0808 0.0807
Echinococcus granulosus cysteine protease 0.0761 0.2028 0.2028
Loa Loa (eye worm) hypothetical protein 0.0061 0.0113 0.0112
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0054 0.0053
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0761 0.2028 0.2028
Schistosoma mansoni cathepsin s 0.0422 0.1101 0.11
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0043 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0422 0.1101 0.11
Entamoeba histolytica hypothetical protein 0.0023 0.0007 0.0015
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0065
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.0054 0.0053
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.004 0.0054 0.0053
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.004 0.0054 0.0053
Echinococcus multilocularis microtubule associated protein 2 0.1573 0.4251 0.425
Leishmania major silent information regulator 2, putative 0.0124 0.0284 0.0435
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Brugia malayi Histone deacetylase family protein 0.0099 0.0214 0.0213
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.001 0.0009
Schistosoma mansoni Mername-AA248 (C02 family) 0.0993 0.2663 0.2662
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.004 0.0054 0.0053
Trypanosoma cruzi kinesin, putative 0.0701 0.1862 0.1861
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0022 0.0032
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0043
Trypanosoma cruzi cysteine proteinase, putative 0.0761 0.2028 0.2028
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.004 0.0054 0.0142
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0158 0.0377 0.0376
Schistosoma mansoni inhibitor of apoptosis protein 0.0184 0.0448 0.0447
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0022 0.0039
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0052 0.0114
Loa Loa (eye worm) peptidase C13 family protein 0.0152 0.0361 0.036
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0066 0.0065
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0315 0.0808 0.2167
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0054 0.0142
Echinococcus granulosus histone deacetylase 6 0.0099 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0158 0.0377 0.0376
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0124 0.0284 0.0283
Mycobacterium ulcerans hypothetical protein 0.016 0.0381 0.1415
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.001 0.0009
Leishmania major histone deacetylase, putative 0.0088 0.0185 0.0282
Brugia malayi programmed cell death protein 6 0.0158 0.0377 0.0376
Plasmodium falciparum proteasome subunit beta type-4 0.004 0.0054 0.0142
Brugia malayi Angiotensin-converting enzyme family protein 0.1212 0.3262 0.3262
Trypanosoma cruzi metacaspase, putative 0.0044 0.0066 0.0065
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0052 0.0138
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.001 0.0009
Loa Loa (eye worm) histone deacetylase 7A 0.0099 0.0214 0.0213
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0042 0.0041
Trypanosoma cruzi calmodulin, putative 0.0158 0.0377 0.0376
Schistosoma mansoni neuronal calcium sensor 0.0158 0.0377 0.0376
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.004 0.0054 0.0142
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0031 0.003 0.0045
Toxoplasma gondii centrin 0.0158 0.0377 0.0577
Leishmania major phospholipase c-like protein 0.0158 0.0377 0.0577
Brugia malayi Eukaryotic aspartyl protease family protein 0.0031 0.003 0.0029
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Onchocerca volvulus 0.016 0.0381 0.0571
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0052 0.0086 0.0085
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.004 0.0054 0.0053
Trypanosoma brucei metacaspase MCA3 0.0044 0.0066 0.01
Entamoeba histolytica pyruvate kinase, putative 0.0028 0.0022 0.0055
Mycobacterium ulcerans transglutaminase family protein 0.0291 0.0741 0.276
Echinococcus granulosus gamma secretase subunit aph 1 0.0267 0.0676 0.0675
Entamoeba histolytica cysteine proteinase, putative 0.1381 0.3724 1
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Echinococcus granulosus calcium uptake protein 1 0.0161 0.0384 0.0383
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0293 0.0745 0.0745
Brugia malayi nuclear receptor NHR-88 0.0024 0.001 0.0009
Plasmodium falciparum serine repeat antigen 5 0.0339 0.0872 0.2341
Echinococcus granulosus Glycosyl transferase family 35 0.0118 0.0269 0.0268
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Echinococcus multilocularis protein jagged 2 0.0026 0.0016 0.0015
Brugia malayi Pyruvate kinase, muscle isozyme 0.004 0.0055 0.0054
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0761 0.2028 0.2028
Trypanosoma brucei proteasome alpha 7 subunit 0.004 0.0054 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.0648 0.0647
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.0745
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0915 0.245 0.375
Echinococcus multilocularis neuronal calcium sensor 0.0158 0.0377 0.0376
Giardia lamblia Proteasome subunit beta type 4 precursor 0.004 0.0054 0.0143
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0158 0.0377 0.0376
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0031 0.003 0.0029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0745 0.0745
Toxoplasma gondii prolyl endopeptidase 0.2401 0.6516 1
Schistosoma mansoni hypothetical protein 0.0117 0.0264 0.0263
Trypanosoma cruzi cruzipain precursor, putative 0.0422 0.1101 0.11
Entamoeba histolytica calmodulin, putative 0.0158 0.0377 0.101
Echinococcus granulosus neurogenic locus notch protein 4 0.0026 0.0016 0.0015
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0339 0.0872 0.2341
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.004 0.0054 0.0053
Plasmodium falciparum serine repeat antigen 7 0.0339 0.0872 0.2341
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0043
Onchocerca volvulus Peroxidasin homolog 0.032 0.0819 0.1245
Echinococcus multilocularis cathepsin L 0.0761 0.2028 0.2028
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0293 0.0745 0.1143
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0015
Leishmania major cathepsin L-like protease 0.1487 0.4014 0.6159
Trypanosoma brucei histone deacetylase 2 0.0042 0.006 0.0091
Schistosoma mansoni aldehyde dehydrogenase 0.0141 0.033 0.0329
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.001 0.0009
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0654 0.1735 0.1735
Trypanosoma cruzi centrin, putative 0.0162 0.0387 0.0386
Trypanosoma cruzi cysteine peptidase, putative 0.1487 0.4014 0.4013
Trichomonas vaginalis calmodulin, putative 0.0162 0.0387 0.1037
Echinococcus granulosus expressed protein 0.0841 0.2247 0.2246
Brugia malayi Proteasome subunit alpha type 1 0.004 0.0054 0.0053
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0041 0.0062
Entamoeba histolytica grainin 2 0.0162 0.0387 0.1037
Loa Loa (eye worm) hypothetical protein 0.0422 0.1101 0.11
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0032 0.0048
Echinococcus multilocularis calumenin 0.0161 0.0384 0.0383
Brugia malayi Histone deacetylase family protein 0.0099 0.0214 0.0213
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0102 0.0224 0.0343
Echinococcus granulosus calpain 7 C02 family 0.0993 0.2663 0.2662
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0315 0.0808 0.2167
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2805 0.7621 0.7621
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0059 0.0157
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0066 0.0065
Echinococcus multilocularis pyruvate kinase 0.0032 0.0032 0.0031
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0048 0.0075 0.0199
Echinococcus granulosus cathepsin L 0.0339 0.0872 0.0871
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Schistosoma mansoni glycogen phosphorylase 0.0118 0.0269 0.0268
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0185 0.0184
Trypanosoma brucei histone deacetylase 4 0.0099 0.0214 0.0327
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0002
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0315 0.0808 0.0807
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0016 0.0015
Onchocerca volvulus 0.032 0.0819 0.1245
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.001 0.0009
Plasmodium falciparum plasmepsin III 0.0031 0.003 0.0078
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.004 0.0054 0.0053
Trypanosoma cruzi cytochrome P450, putative 0.0036 0.0042 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0101 0.01
Loa Loa (eye worm) proteasome subunit alpha type 2 0.004 0.0054 0.0053
Schistosoma mansoni hypothetical protein 0.0048 0.0075 0.0074
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3674 1 1
Trypanosoma brucei proteasome beta 6 subunit 0.0142 0.0333 0.0509
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1381 0.3724 0.3723
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0745 0.1143
Loa Loa (eye worm) blistered cuticle protein 3 0.032 0.0819 0.0819
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Trypanosoma brucei Calpain-like protein CALP1.3 0.0293 0.0745 0.1143
Leishmania major i/6 autoantigen-like protein 0.0158 0.0377 0.0577
Echinococcus granulosus caspase 8 0.0044 0.0066 0.0065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0993 0.2663 0.2662
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1381 0.3724 1
Brugia malayi hypothetical protein 0.0172 0.0416 0.0415
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Schistosoma mansoni kinase 0.0058 0.0103 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0023 0.0074
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0059 0.0157
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0022 0.007
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0023 0.0004
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0036 0.0042 0.0146
Schistosoma mansoni hypothetical protein 0.0027 0.0018 0.0017
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0029 0.0043
Trypanosoma brucei Calpain-like protein 1.1 0.0293 0.0745 0.1143
Onchocerca volvulus 0.0039 0.0052 0.0066
Onchocerca volvulus 0.0138 0.0321 0.0479
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0339 0.0872 0.0871
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0054 0.0081
Giardia lamblia Cathepsin B precursor 0.0339 0.0872 0.2359
Leishmania major protein kinase, putative 0.0158 0.0378 0.0579
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0339 0.0872 0.2341
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0041 0.0108
Loa Loa (eye worm) hypothetical protein 0.032 0.0819 0.0819
Brugia malayi Cathepsin L-like precursor 0.1381 0.3724 0.3723
Entamoeba histolytica cysteine protease, putative 0.0761 0.2028 0.5446
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0026 0.0025
Loa Loa (eye worm) pyruvate kinase 0.004 0.0055 0.0054
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0066 0.0175
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0028
Toxoplasma gondii aldehyde dehydrogenase 0.0141 0.033 0.0505
Brugia malayi Regulator of G protein signaling domain containing protein 0.0043 0.0063 0.0062
Trichomonas vaginalis calmodulin, putative 0.0158 0.0377 0.101
Echinococcus multilocularis fibropellin Ia 0.0026 0.0016 0.0015
Mycobacterium leprae Conserved hypothetical protein 0.0291 0.0741 0.2709
Trypanosoma brucei prolyl oligopeptidase, putative 0.0998 0.2675 0.4104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1487 0.4014 0.6159
Echinococcus granulosus histone deacetylase 8 0.0042 0.006 0.006
Toxoplasma gondii calmodulin CAM1 0.0161 0.0384 0.0588
Onchocerca volvulus Legumain homolog 0.0152 0.0361 0.054
Entamoeba histolytica calmodulin, putative 0.0158 0.0377 0.101
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0293 0.0745 0.2
Plasmodium vivax proteasome subunit alpha type-1, putative 0.004 0.0054 0.0142
Loa Loa (eye worm) hypothetical protein 0.016 0.0381 0.038
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0185 0.0184
Schistosoma mansoni hypothetical protein 0.0158 0.0377 0.0376

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.6834 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.2387 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 4.184 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) [Related pubchem assays: 1490 (qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase)), 1819 (Probe Development Summary of Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase))] ChEMBL. No reference
Potency (functional) 5.0119 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.9955 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 14.581 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of Nrf2 Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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