Detailed information for compound 1411249

Basic information

Technical information
  • TDR Targets ID: 1411249
  • Name: (4-methoxyphenyl)-[4-(3-phenylphenyl)-4,9-dia zaspiro[5.5]undecan-9-yl]methanone
  • MW: 440.577 | Formula: C29H32N2O2
  • H donors: 0 H acceptors: 1 LogP: 5.89 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C(=O)N1CCC2(CC1)CCCN(C2)c1cccc(c1)c1ccccc1
  • InChi: 1S/C29H32N2O2/c1-33-27-13-11-24(12-14-27)28(32)30-19-16-29(17-20-30)15-6-18-31(22-29)26-10-5-9-25(21-26)23-7-3-2-4-8-23/h2-5,7-14,21H,6,15-20,22H2,1H3
  • InChiKey: ZLUDUZWBSCZSID-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • NCGC00011408
  • PCOP-473276

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Giardia lamblia Cathepsin L precursor 0.0197 0.0917 0.2461
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0527 0.2647 0.3386
Echinococcus multilocularis proteasome (prosome, macropain) 0.0086 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0041 0.0097 0.0097
Brugia malayi programmed cell death protein 6 0.0093 0.0371 0.0371
Brugia malayi Cathepsin L-like precursor 0.0833 0.4248 0.4248
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.193 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0543 0.0543
Echinococcus multilocularis survival motor neuron protein 1 0.0246 0.1175 0.1175
Loa Loa (eye worm) programmed cell death protein 6 0.0095 0.038 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0917 0.2159
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0097 0.0097
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0097 0.0097
Brugia malayi Proteasome A-type and B-type family protein 0.0086 0.0331 0.0331
Toxoplasma gondii cathepsin CPC2 0.0197 0.0917 0.1173
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0455 0.2267 0.5338
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0176 0.0806 0.0806
Schistosoma mansoni calmodulin 0.0093 0.0371 0.0371
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0048 0.0132 0.0132
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0097 0.0097
Mycobacterium tuberculosis Conserved protein 0.0544 0.2733 0.3986
Echinococcus multilocularis lysosomal alpha glucosidase 0.0155 0.0697 0.0697
Schistosoma mansoni tar DNA-binding protein 0.0043 0.011 0.011
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0093 0.0371 0.0875
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0197 0.0917 0.2461
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0197 0.0917 0.2148
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.026 0.026
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0066 0.0066
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0093 0.0371 0.0371
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0176 0.0806 0.0806
Brugia malayi Cathepsin L-like precursor 0.0833 0.4248 0.4248
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0733 0.3726 0.4763
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0586 0.2956 0.2956
Echinococcus granulosus calbindin 32 0.0095 0.038 0.038
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0063
Loa Loa (eye worm) proteasome subunit beta type 1 0.0066 0.0231 0.0231
Plasmodium falciparum cysteine proteinase falcipain 1 0.0455 0.2267 0.5331
Loa Loa (eye worm) hypothetical protein 0.1554 0.8029 0.8029
Echinococcus granulosus glycogen phosphorylase 0.0107 0.0443 0.0443
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0034 0.0063 0.0149
Plasmodium falciparum serine repeat antigen 8 0.0197 0.0917 0.2148
Plasmodium falciparum centrin-1 0.0093 0.0371 0.0862
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0833 0.4248 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0066 0.0141
Brugia malayi Cytochrome P450 family protein 0.0024 0.0007 0.0007
Brugia malayi beta-lactamase family protein 0.0035 0.0066 0.0066
Trypanosoma brucei hypothetical protein, conserved 0.0093 0.0371 0.0467
Schistosoma mansoni hypothetical protein 0.0024 0.0006 0.0006
Onchocerca volvulus 0.0061 0.0202 0.0258
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0097 0.0097
Trichomonas vaginalis alpha-glucosidase, putative 0.0034 0.0063 0.0149
Echinococcus multilocularis gamma secretase subunit aph 1 0.0243 0.1154 0.1154
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1053 0.153
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Entamoeba histolytica cysteine proteinase, putative 0.0575 0.2897 0.6821
Loa Loa (eye worm) hypothetical protein 0.0197 0.0917 0.0917
Echinococcus granulosus cathepsin b 0.193 1 1
Leishmania major calpain protease-like protein 0.0176 0.0806 0.1025
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Brugia malayi Cell death protein 3 precursor 0.0061 0.0202 0.0202
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0097 0.0097
Brugia malayi Trypsin family protein 0.0034 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0176 0.0806 0.0806
Schistosoma mansoni hypothetical protein 0.0024 0.0007 0.0007
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Entamoeba histolytica cysteine proteinase, putative 0.0455 0.2267 0.5338
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0917 0.0917
Plasmodium vivax unspecified product 0.0197 0.0917 0.2148
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0066 0.0231 0.0231
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.021 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1024
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0097 0.0229
Leishmania major proteasome beta 2 subunit, putative 0.0041 0.0098 0.0119
Plasmodium vivax vivapain-3 0.0455 0.2267 0.5331
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0042 0.0105 0.0314
Trichomonas vaginalis maltase-glucoamylase, putative 0.0034 0.0063 0.0149
Leishmania major histone deacetylase, putative 0.01 0.0408 0.0514
Mycobacterium ulcerans hypothetical protein 0.0544 0.2733 0.8727
Toxoplasma gondii ABC1 family protein 0.0035 0.0066 0.0084
Schistosoma mansoni microtubule-associated protein tau 0.1456 0.7519 0.7519
Mycobacterium leprae Probable lipase LipE 0.0035 0.0066 0.019
Onchocerca volvulus 0.0034 0.0063 0.0081
Echinococcus granulosus glycoprotein Antigen 5 0.0034 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.193 1 1
Echinococcus multilocularis calmodulin 0.0093 0.0371 0.0371
Echinococcus multilocularis calbindin 32 0.0095 0.038 0.038
Mycobacterium tuberculosis Conserved protein 0.0035 0.0066 0.0087
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Brugia malayi Cathepsin L-like precursor 0.0833 0.4248 0.4248
Mycobacterium ulcerans putative transglutaminase-like protein 0.0544 0.2733 0.8727
Mycobacterium ulcerans beta-lactamase 0.0035 0.0066 0.019
Trypanosoma cruzi cytochrome P450, putative 0.0042 0.0105 0.0105
Trypanosoma brucei calpain-like protein, putative 0.0586 0.2956 0.3776
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0408 0.0408
Echinococcus multilocularis glycogen phosphorylase 0.0107 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0052 0.0156 0.0156
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0097 0.0097
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0052 0.0066
Trypanosoma brucei glucosidase, putative 0.0034 0.0063 0.0073
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.035 0.0824
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0197 0.0917 0.0917
Schistosoma mansoni chromobox protein 0.0058 0.0185 0.0185
Entamoeba histolytica hypothetical protein 0.0197 0.0917 0.2159
Leishmania major cathepsin L-like protease 0.0833 0.4248 0.5431
Brugia malayi TAR-binding protein 0.0043 0.011 0.011
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0197 0.0917 0.2148
Schistosoma mansoni calpain-7 (C02 family) 0.0593 0.299 0.299
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0097 0.0097
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0125 0.0125
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0066 0.0155
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0917 0.0917
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0065 0.0083
Entamoeba histolytica hypothetical protein, conserved 0.0095 0.038 0.0895
Entamoeba histolytica cysteine proteinase 1, putative 0.0455 0.2267 0.5338
Schistosoma mansoni centrin 0.0093 0.0371 0.0371
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0197 0.0917 0.2461
Onchocerca volvulus 0.0833 0.4248 0.5434
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0281 0.1354 0.1726
Trypanosoma brucei cytochrome P450, putative 0.0042 0.0105 0.0126
Brugia malayi Pre-SET motif family protein 0.0432 0.2149 0.2149
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Leishmania major calmodulin, putative 0.0093 0.0371 0.0468
Entamoeba histolytica cysteine protease, putative 0.0197 0.0917 0.2159
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0086 0.0331 0.1039
Echinococcus multilocularis transmembrane protease serine 3 0.0034 0.0063 0.0063
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0197 0.0917 0.2148
Giardia lamblia Cathepsin L-like protease 0.0197 0.0917 0.2461
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0156 0.0156
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0086 0.0331 0.0474
Brugia malayi Papain family cysteine protease containing protein 0.0197 0.0917 0.0917
Trichomonas vaginalis calpain, putative 0.0176 0.0806 0.1899
Schistosoma mansoni jumonji/arid domain-containing protein 0.005 0.0146 0.0146
Trypanosoma brucei calpain, putative 0.0176 0.0806 0.1024
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1024
Loa Loa (eye worm) hypothetical protein 0.0197 0.0917 0.0917
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0007 0.0001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0544 0.2733 0.3986
Toxoplasma gondii histone deacetylase HDAC2 0.0089 0.035 0.0448
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0185 0.0853 0.2008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0917 0.2159
Toxoplasma gondii centrin 0.0093 0.0371 0.0475
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0097 0.0097
Trichomonas vaginalis centrin, putative 0.0093 0.0371 0.0875
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1513 0.7817 0.7817
Leishmania major i/6 autoantigen-like protein 0.0093 0.0371 0.0468
Leishmania major cytochrome p450-like protein 0.0024 0.0007 0.0001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0455 0.2267 0.2267
Echinococcus granulosus EF HAND 1 calcium binding site 0.0093 0.0371 0.0371
Loa Loa (eye worm) histone deacetylase 0.01 0.0408 0.0408
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0097 0.0097
Brugia malayi Cytochrome P450 family protein 0.0042 0.0105 0.0105
Leishmania major calmodulin-like protein 0.0093 0.0371 0.0468
Trypanosoma brucei protein I/6 0.0093 0.0371 0.0467
Onchocerca volvulus 0.0052 0.0156 0.02
Onchocerca volvulus Cathepsin L homolog 0.0833 0.4248 0.5434
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0097 0.0097
Echinococcus multilocularis prolyl endopeptidase 0.1513 0.7817 0.7817
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0097 0.0097
Schistosoma mansoni centrin-related 0.0093 0.0371 0.0371
Plasmodium falciparum calpain 0.0176 0.0806 0.1887
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0258 0.1233 0.1233
Loa Loa (eye worm) proteasome subunit beta type 2 0.0041 0.0098 0.0098
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.062 0.3131 0.4001
Brugia malayi Cathepsin L-like precursor 0.0833 0.4248 0.4248
Plasmodium falciparum peptidase, putative 0.0185 0.0853 0.1997
Brugia malayi Cathepsin L-like precursor 0.0575 0.2897 0.2897
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0197 0.0917 0.2159
Plasmodium vivax proteasome subunit beta type-2, putative 0.0041 0.0098 0.0218
Schistosoma mansoni mitochondrial solute carrier 0.0093 0.0371 0.0371
Echinococcus multilocularis calpain 7 (C02 family) 0.0586 0.2956 0.2956
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0041 0.0097 0.0097
Echinococcus multilocularis cathepsin L 0.0197 0.0917 0.0917
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0065 0.0153
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0185 0.0853 0.2008
Echinococcus granulosus geminin 0.0169 0.0769 0.0769
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1647 0.8518 0.8518
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.035 0.0824
Schistosoma mansoni cpg binding protein 0.003 0.0039 0.0039
Echinococcus multilocularis cathepsin L 0.0455 0.2267 0.2267
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0066 0.0066
Echinococcus granulosus cysteine protease 0.0455 0.2267 0.2267
Giardia lamblia Cathepsin B precursor 0.0733 0.3726 1
Brugia malayi prolyl oligopeptidase family protein 0.0185 0.0853 0.0853
Brugia malayi calpain family protein 1 0.1554 0.8029 0.8029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0362 0.0362
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0034 0.0063 0.0063
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0066 0.0076
Echinococcus multilocularis inhibitor of apoptosis protein 0.0133 0.058 0.058
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0043 0.011 0.011
Plasmodium falciparum serine repeat antigen 3 0.0197 0.0917 0.2148
Brugia malayi fibroinase precursor 0.0197 0.0917 0.0917
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0109 0.014
Brugia malayi Cathepsin L-like precursor 0.0258 0.1233 0.1233
Plasmodium vivax serine-repeat antigen (SERA) 0.0197 0.0917 0.2148
Entamoeba histolytica protein kinase, putative 0.041 0.2032 0.4783
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0202 0.0258
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Entamoeba histolytica grainin, putative 0.0095 0.038 0.0895
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0341 0.0341
Echinococcus granulosus cathepsin L cysteine proteinase 0.0833 0.4248 0.4248
Onchocerca volvulus 0.0197 0.0917 0.1173
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0197 0.0917 0.2159
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0066
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0105 0.0105
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0041 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0034 0.0063 0.0063
Trypanosoma brucei calpain, putative 0.0176 0.0806 0.1024
Schistosoma mansoni hypothetical protein 0.0402 0.1992 0.1992
Brugia malayi Cathepsin L-like precursor 0.0833 0.4248 0.4248
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0066 0.0066
Trypanosoma brucei Calpain-like protein 1.2 0.0176 0.0806 0.1024
Loa Loa (eye worm) hypothetical protein 0.0197 0.0917 0.0917
Echinococcus granulosus acylamino acid releasing enzyme 0.0185 0.0853 0.0853
Trypanosoma cruzi caltractin, putative 0.0093 0.0371 0.0371
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0197 0.0917 0.2148
Giardia lamblia Hypothetical protein 0.0544 0.2733 0.7334
Brugia malayi RNA binding protein 0.0043 0.011 0.011
Plasmodium falciparum serine repeat antigen 4 0.0197 0.0917 0.2148
Trypanosoma cruzi cysteine proteinase, putative 0.0455 0.2267 0.2267
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0093 0.0371 0.0371
Brugia malayi Papain family cysteine protease containing protein 0.0455 0.2267 0.2267
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0917 0.2159
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0197 0.0917 0.2148
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0281 0.1354 0.1725
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.3776
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0066 0.0231 0.0544
Trichomonas vaginalis esterase, putative 0.0035 0.0066 0.0155
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0197 0.0917 0.2461
Giardia lamblia Proteasome subunit beta type 2 0.0041 0.0098 0.0264
Entamoeba histolytica glycogen phosphorylase, putative 0.0107 0.0443 0.1042
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0185 0.0853 0.0853
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0548 0.0548
Mycobacterium ulcerans proteasome PrcB 0.0086 0.0331 0.1039
Giardia lamblia Cathepsin L precursor 0.0197 0.0917 0.2461
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0063 0.0063
Schistosoma mansoni histone deacetylase 1 2 3 0.0043 0.0108 0.0108
Brugia malayi Thioredoxin family protein 0.0544 0.2733 0.2733
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0052 0.0122
Echinococcus multilocularis chromobox protein 1 0.0058 0.0185 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Leishmania major cathepsin L-like protease 0.0833 0.4248 0.5431
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0176 0.0806 0.1899
Trypanosoma cruzi cytochrome P450, putative 0.0042 0.0105 0.0105
Onchocerca volvulus 0.0035 0.0066 0.0084
Brugia malayi Trypsin family protein 0.0034 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0197 0.0917 0.2159
Mycobacterium tuberculosis Conserved protein 0.0035 0.0066 0.0087
Entamoeba histolytica cysteine proteinase 2 0.0455 0.2267 0.5338
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0125 0.0378
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0455 0.2267 0.2267
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0833 0.4248 1
Echinococcus granulosus gamma secretase subunit aph 1 0.0243 0.1154 0.1154
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0125 0.0294
Trichomonas vaginalis calcineurin B subunit, putative 0.0095 0.038 0.0895
Schistosoma mansoni alpha-glucosidase 0.0134 0.0584 0.0584
Schistosoma mansoni Mername-AA248 (C02 family) 0.0586 0.2956 0.2956
Echinococcus multilocularis cathepsin L cysteine protease 0.0833 0.4248 0.4248
Brugia malayi carbohydrate phosphorylase 0.0107 0.0443 0.0443
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0031 0.0031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0098 0.0232
Trypanosoma brucei oligopeptidase b 0.062 0.3131 0.4
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0197 0.0917 0.2159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Trypanosoma brucei kinesin, putative 0.041 0.2032 0.2593
Entamoeba histolytica calcium binding family protein 0.0093 0.0371 0.0875
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.0098 0.0098
Toxoplasma gondii histone deacetylase HDAC3 0.0089 0.035 0.0448
Echinococcus granulosus histone deacetylase 0.01 0.0408 0.0408
Trypanosoma cruzi centrin-3 0.0093 0.0371 0.0371
Trypanosoma cruzi calmodulin, putative 0.0093 0.0371 0.0371
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0281 0.1354 0.1354
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Echinococcus multilocularis neurocalcin 0.0093 0.0371 0.0371
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0455 0.2267 0.2267
Onchocerca volvulus 0.0159 0.0718 0.0919
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0833 0.4248 0.4248
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0133 0.058 0.058
Onchocerca volvulus 0.0133 0.058 0.0742
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0586 0.2956 0.2956
Entamoeba histolytica cysteine proteinase, putative 0.0455 0.2267 0.5338
Entamoeba histolytica cysteine proteinase, putative 0.0833 0.4248 1
Echinococcus granulosus calcium uptake protein 1 0.0095 0.038 0.038
Onchocerca volvulus 0.0025 0.0015 0.002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0176 0.0806 0.0806
Brugia malayi Trypsin-like protease protein 5 0.0034 0.0063 0.0063
Onchocerca volvulus 0.0575 0.2897 0.3707
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0155 0.0697 0.0697
Loa Loa (eye worm) trypsin family protein 0.0034 0.0063 0.0063
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0007 0.0007
Toxoplasma gondii centrin, putative 0.0093 0.0371 0.0475
Plasmodium vivax unspecified product 0.0455 0.2267 0.5331
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Giardia lamblia Glycogen phosphorylase 0.0107 0.0443 0.1188
Echinococcus granulosus histone deacetylase 6 0.01 0.0408 0.0408
Brugia malayi Papain family cysteine protease containing protein 0.0197 0.0917 0.0917
Echinococcus multilocularis Glycosyl transferase, family 35 0.0107 0.0443 0.0443
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Plasmodium vivax histone deacetylase 2, putative 0.01 0.0408 0.0947
Schistosoma mansoni calmodulin related calcium binding protein 0.0093 0.0371 0.0371
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.0543 0.0784
Brugia malayi cathepsin F-like cysteine proteinase 0.0258 0.1233 0.1233
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0176 0.0806 0.0806
Toxoplasma gondii histone deacetylase HDAC1 0.01 0.0408 0.0521
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0197 0.0917 0.0917
Mycobacterium leprae Conserved hypothetical protein 0.0544 0.2733 0.8727
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0097 0.0097
Echinococcus multilocularis histone deacetylase 1 0.0089 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0093 0.0371 0.0371
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0097 0.0097
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0093 0.0371 0.0875
Schistosoma mansoni reticulocalbin 0.0093 0.0371 0.0371
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Mycobacterium tuberculosis Long conserved protein 0.0544 0.2733 0.3986
Trichomonas vaginalis glycogen phosphorylase, putative 0.0107 0.0443 0.1042
Trypanosoma brucei I/6 autoantigen 0.0093 0.0371 0.0467
Echinococcus granulosus histone deacetylase 3 0.0089 0.035 0.035
Mycobacterium ulcerans glutaminase 0.0261 0.125 0.3979
Loa Loa (eye worm) fibroinase 0.0833 0.4248 0.4248
Plasmodium falciparum serine repeat antigen 7 0.0197 0.0917 0.2148
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0048 0.0132 0.0132
Leishmania major histone deacetylase, putative 0.0089 0.035 0.044
Loa Loa (eye worm) calpain family protein 1 0.1144 0.588 0.588
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0097 0.0097
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Trichomonas vaginalis conserved hypothetical protein 0.0176 0.0806 0.1899
Leishmania major histone deacetylase, putative 0.0089 0.035 0.044
Echinococcus granulosus tumor protein p63 0.0356 0.1752 0.1752
Loa Loa (eye worm) hypothetical protein 0.0133 0.058 0.058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0362 0.0362
Loa Loa (eye worm) calpain D 0.0176 0.0806 0.0806
Brugia malayi Heterochromatin protein 1 0.0058 0.0185 0.0185
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Loa Loa (eye worm) glutaminase 2 0.0261 0.125 0.125
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0197 0.0917 0.0917
Toxoplasma gondii prolyl endopeptidase 0.1513 0.7817 1
Trypanosoma brucei proteasome beta 6 subunit 0.0066 0.0231 0.0287
Brugia malayi RNA recognition motif domain containing protein 0.0043 0.011 0.011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0281 0.1354 0.1354
Loa Loa (eye worm) hypothetical protein 0.0095 0.0383 0.0383
Entamoeba histolytica hypothetical protein 0.0041 0.0097 0.0229
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0544 0.2733 0.2733
Echinococcus multilocularis histone deacetylase 0.01 0.0408 0.0408
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0417 0.2068 0.2068
Echinococcus multilocularis histone deacetylase 6 0.01 0.0408 0.0408
Trypanosoma cruzi cysteine peptidase, putative 0.0933 0.4774 0.4774
Trypanosoma brucei Aph-1 protein, putative 0.0095 0.0378 0.0476
Leishmania major cathepsin L-like protease 0.0933 0.4774 0.6105
Trypanosoma cruzi kinesin, putative 0.041 0.2032 0.2032
Plasmodium vivax proteasome subunit beta type-5, putative 0.0086 0.0331 0.0767
Loa Loa (eye worm) hypothetical protein 0.0063 0.0215 0.0215
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0048 0.0132 0.0354
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0066 0.0087
Trichomonas vaginalis calcineurin B subunit, putative 0.0093 0.0371 0.0875
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0097 0.0097
Toxoplasma gondii hypothetical protein 0.0185 0.0853 0.1091
Loa Loa (eye worm) hypothetical protein 0.0197 0.0917 0.0917
Entamoeba histolytica hypothetical protein 0.0041 0.0097 0.0229
Trypanosoma cruzi major cysteine proteinase, putative 0.0197 0.0917 0.0917
Loa Loa (eye worm) hypothetical protein 0.0258 0.1233 0.1233
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1647 0.8518 0.8518
Echinococcus multilocularis glycoprotein Antigen 5 0.0034 0.0063 0.0063
Leishmania major centrin, putative 0.0093 0.0371 0.0468
Echinococcus multilocularis EF hand domain containing family member A2 0.0093 0.0371 0.0371
Trichomonas vaginalis sucrase-isomaltase, putative 0.0034 0.0063 0.0149
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0097 0.0097
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0176 0.0806 0.1032
Onchocerca volvulus 0.0732 0.3722 0.4762
Echinococcus granulosus calpain 0.0586 0.2956 0.2956
Onchocerca volvulus 0.0093 0.0371 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0185 0.0853 0.2008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0833 0.4248 0.4248
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Trypanosoma brucei centrin, putative 0.0093 0.0371 0.0467
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0176 0.0806 0.1024
Leishmania major calcineurin B subunit, putative 0.0093 0.0371 0.0468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0917 0.2159
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Brugia malayi prolyl oligopeptidase family protein 0.0281 0.1354 0.1354
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0034 0.0063 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0034 0.0063 0.0149
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.193 1 1
Echinococcus granulosus Transglutaminase 0.0544 0.2733 0.2733
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0066 0.0231 0.0296
Echinococcus multilocularis tissue type plasminogen activator 0.0024 0.0006 0.0006
Schistosoma mansoni histone deacetylase hda2 0.0106 0.044 0.044
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0408 0.0408
Loa Loa (eye worm) prolyl oligopeptidase 0.0527 0.2647 0.2647
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Onchocerca volvulus 0.0035 0.0066 0.0084
Echinococcus multilocularis caspase 2 0.0061 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0061 0.0202 0.0202
Schistosoma mansoni cathepsin S (C01 family) 0.0197 0.0917 0.0917
Giardia lamblia Cathepsin L precursor 0.0197 0.0917 0.2461
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0086 0.0331 0.0331
Trypanosoma cruzi cysteine peptidase, putative 0.0455 0.2267 0.2267
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1024
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0066 0.0087
Loa Loa (eye worm) hypothetical protein 0.0833 0.4248 0.4248
Brugia malayi Glycosyl hydrolases family 31 protein 0.0034 0.0063 0.0063
Echinococcus granulosus cpg binding protein 0.003 0.0039 0.0039
Brugia malayi histone deacetylase 1 (HD1) 0.0089 0.035 0.035
Echinococcus granulosus centrin 2 0.0093 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0032 0.0052 0.0052
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0185 0.0853 0.1084
Echinococcus granulosus histone deacetylase 7 0.01 0.0408 0.0408
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.2956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Toxoplasma gondii calmodulin CAM1 0.0095 0.038 0.0486
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0086 0.0331 0.0889
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0176 0.0806 0.0806
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0093 0.0371 0.0371
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0097 0.0097
Echinococcus multilocularis 0.0024 0.0007 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0066 0.0155
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0093 0.0371 0.0371
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0108 0.0108
Brugia malayi Cathepsin L-like precursor 0.0575 0.2897 0.2897
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0258 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0066
Trypanosoma brucei histone deacetylase 1 0.0089 0.035 0.044
Echinococcus granulosus lysosomal alpha glucosidase 0.0155 0.0697 0.0697
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.062 0.3131 0.4
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0093 0.0371 0.0862
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Trichomonas vaginalis conserved hypothetical protein 0.0197 0.0917 0.2159
Schistosoma mansoni histone deacetylase hda2 0.0043 0.0108 0.0108
Brugia malayi Cathepsin L-like precursor 0.0833 0.4248 0.4248
Trypanosoma cruzi cysteine protease, putative 0.0455 0.2267 0.2267
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0063 0.021 0.021
Loa Loa (eye worm) cytochrome P450 0.0024 0.0007 0.0007
Echinococcus granulosus EF hand domain containing family member A2 0.0093 0.0371 0.0371
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0197 0.0917 0.0917
Plasmodium vivax hypothetical protein, conserved 0.0185 0.0853 0.1997
Trypanosoma brucei histone deacetylase, putative 0.01 0.0408 0.0513
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Giardia lamblia Cysteine protease 0.0197 0.0917 0.2461
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0097 0.0097
Onchocerca volvulus 0.0028 0.0031 0.0039
Plasmodium falciparum serine repeat antigen 9 0.0197 0.0917 0.2148
Loa Loa (eye worm) hypothetical protein 0.0041 0.0097 0.0097
Schistosoma mansoni calpain-7 (C02 family) 0.0593 0.299 0.299
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Echinococcus granulosus tissue type plasminogen activator 0.0024 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0917 0.2159
Loa Loa (eye worm) prolyl oligopeptidase 0.0185 0.0853 0.0853
Schistosoma mansoni histone deacetylase 4 5 0.01 0.0408 0.0408
Trypanosoma cruzi I/6 autoantigen, putative 0.0093 0.0371 0.0371
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0197 0.0917 0.0917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Brugia malayi EF hand family protein 0.0095 0.038 0.038
Brugia malayi gamma-secretase subunit aph-1 0.0243 0.1154 0.1154
Entamoeba histolytica cysteine protease, putative 0.0197 0.0917 0.2159
Loa Loa (eye worm) cysteine protease 0.0833 0.4248 0.4248
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0185 0.0853 0.2008
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1328 0.6846 1
Leishmania major cathepsin L-like protease 0.0833 0.4248 0.5431
Toxoplasma gondii hypothetical protein 0.0176 0.0806 0.1032
Echinococcus granulosus histone deacetylase 8 0.0043 0.0108 0.0108
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0048 0.0132 0.0132
Echinococcus granulosus calpain 7 C02 family 0.0586 0.2956 0.2956
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1647 0.8518 0.8518
Loa Loa (eye worm) hypothetical protein 0.0575 0.2897 0.2897
Plasmodium falciparum histone deacetylase 2 0.01 0.0408 0.0947
Giardia lamblia Proteasome subunit beta type 1 0.0066 0.0231 0.062
Brugia malayi proteasome subunit beta type 1 0.0066 0.0231 0.0231
Brugia malayi proteasome subunit beta type 2 0.0041 0.0098 0.0098
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0095 0.038 0.038
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Trypanosoma cruzi prolyl endopeptidase 0.1513 0.7817 0.7817
Schistosoma mansoni cathepsin F (C01 family) 0.0575 0.2897 0.2897
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Echinococcus granulosus tar DNA binding protein 0.0043 0.011 0.011
Echinococcus multilocularis calpain family protein 1, d 0.1144 0.588 0.588
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0197 0.0917 0.2148
Trypanosoma cruzi calmodulin, putative 0.0093 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0968 0.4956 0.4956
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0097 0.0229
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0362 0.0362
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.1992 0.1992
Schistosoma mansoni jumonji/arid domain-containing protein 0.005 0.0146 0.0146
Trichomonas vaginalis peptide N-glycanase, putative 0.0544 0.2733 0.6434
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.2956
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0197 0.0917 0.0917
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.035 0.0824
Loa Loa (eye worm) CYP4Cod1 0.0042 0.0105 0.0105
Brugia malayi calpain 5 0.0176 0.0806 0.0806
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0417 0.2068 0.2068
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0007 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0197 0.0917 0.2159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0917 0.2159
Entamoeba histolytica hypothetical protein, conserved 0.0185 0.0853 0.2008
Brugia malayi hypothetical protein 0.0246 0.1175 0.1175
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0231 0.0231
Loa Loa (eye worm) glycogen phosphorylase 0.0107 0.0443 0.0443
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0066 0.0231 0.0544
Echinococcus multilocularis cathepsin L cysteine protease 0.0833 0.4248 0.4248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 0.2897 0.6821
Echinococcus granulosus chromobox protein 1 0.0058 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0246 0.1175 0.1175
Echinococcus multilocularis hypothetical protein 0.0586 0.2956 0.2956
Schistosoma mansoni hypothetical protein 0.0093 0.0371 0.0371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0066
Entamoeba histolytica cysteine protease, putative 0.0197 0.0917 0.2159
Brugia malayi Trypsin family protein 0.0034 0.0063 0.0063
Onchocerca volvulus Cathepsin L homolog 0.0197 0.0917 0.1173
Onchocerca volvulus 0.0833 0.4248 0.5434
Giardia lamblia Hypothetical protein 0.0197 0.0917 0.2461
Echinococcus multilocularis Mastin 0.0034 0.0063 0.0063
Trypanosoma brucei prolyl oligopeptidase, putative 0.062 0.3131 0.4
Plasmodium falciparum histone deacetylase, putative 0.01 0.0408 0.0947
Schistosoma mansoni cathepsin F (C01 family) 0.0833 0.4248 0.4248
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0347 0.1704 0.1704
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0066 0.0231 0.0531
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0063 0.0063
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0066 0.019
Onchocerca volvulus 0.0492 0.2463 0.3151
Trypanosoma cruzi major cysteine proteinase, putative 0.0298 0.1444 0.1444
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0281 0.1354 0.1354
Brugia malayi hypothetical protein 0.0034 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0258 0.1233 0.1233
Trypanosoma cruzi cysteine proteinase, putative 0.0455 0.2267 0.2267
Brugia malayi prolyl oligopeptidase family protein 0.0185 0.0853 0.0853
Brugia malayi Pre-SET motif family protein 0.0063 0.021 0.021
Echinococcus multilocularis Transglutaminase 0.0544 0.2733 0.2733
Loa Loa (eye worm) histone deacetylase 1 0.0089 0.035 0.035
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Echinococcus multilocularis histone deacetylase 7 0.01 0.0408 0.0408
Onchocerca volvulus Glycogen phosphorylase homolog 0.0107 0.0443 0.0566
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0097 0.0097
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0133 0.058 0.058
Plasmodium vivax calpain, putative 0.0586 0.2956 0.6954
Echinococcus granulosus transmembrane protease serine 3 0.0034 0.0063 0.0063
Treponema pallidum fructose-bisphosphate aldolase 0.0242 0.115 0.5
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1513 0.7817 1
Onchocerca volvulus 0.0968 0.4956 0.6341
Schistosoma mansoni survival motor neuron protein 0.005 0.0146 0.0146
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.035 0.0824
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0097 0.0229
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0048 0.0132 0.0132
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0066 0.0087
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0066 0.0155
Brugia malayi calcium-binding protein 0.0093 0.0371 0.0371
Trichomonas vaginalis calcium binding protein, putative 0.0093 0.0371 0.0875
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1554 0.8029 0.8029
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0041 0.0098 0.0218
Entamoeba histolytica prolyl oligopeptidase family protein 0.0185 0.0853 0.2008
Trypanosoma brucei calpain-like protein, putative 0.0586 0.2956 0.3776
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0041 0.0098 0.0232
Echinococcus granulosus Dipeptidyl peptidase 9 0.0281 0.1354 0.1354
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0041 0.0098 0.0098
Brugia malayi Kringle domain containing protein 0.0024 0.0006 0.0006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0155 0.0697 0.0697
Schistosoma mansoni hypothetical protein 0.005 0.0146 0.0146
Echinococcus granulosus histone deacetylase 6 0.0106 0.044 0.044
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.035 0.0824
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0086 0.0331 0.0779
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Trypanosoma cruzi conserved protein 0.0176 0.0806 0.0806
Echinococcus multilocularis enteropeptidase 0.0034 0.0063 0.0063
Echinococcus multilocularis neuronal calcium sensor 0.0093 0.0371 0.0371
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0041 0.0098 0.0126
Echinococcus multilocularis centrin 2 0.0093 0.0371 0.0371
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0097 0.0229
Brugia malayi hypothetical protein 0.0159 0.0718 0.0718
Onchocerca volvulus 0.0072 0.026 0.0332
Schistosoma mansoni tar DNA-binding protein 0.0043 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0917 0.2159
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0733 0.3726 0.8773
Echinococcus multilocularis neutral alpha glucosidase AB 0.0034 0.0063 0.0063
Loa Loa (eye worm) histone deacetylase 7A 0.01 0.0408 0.0408
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0095 0.038 0.038
Echinococcus granulosus cathepsin L 0.0197 0.0917 0.0917
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0281 0.1354 0.1732
Brugia malayi Histone deacetylase family protein 0.01 0.0408 0.0408
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0034 0.0063 0.0149
Echinococcus multilocularis tar DNA binding protein 0.0043 0.011 0.011
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Trichomonas vaginalis glycogen phosphorylase, putative 0.0107 0.0443 0.1042
Onchocerca volvulus 0.0024 0.0006 0.0008
Brugia malayi hypothetical protein 0.0095 0.0383 0.0383
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0586 0.2956 0.2956
Brugia malayi jmjC domain containing protein 0.0049 0.0138 0.0138
Plasmodium vivax proteasome subunit beta type-1, putative 0.0066 0.0231 0.0531
Trichomonas vaginalis alpha-glucosidase, putative 0.0034 0.0063 0.0149
Onchocerca volvulus 0.0833 0.4248 0.5434
Mycobacterium ulcerans transglutaminase family protein 0.0544 0.2733 0.8727
Leishmania major cytochrome p450-like protein 0.0024 0.0007 0.0001
Echinococcus multilocularis lysine specific demethylase 5A 0.0049 0.0138 0.0138
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0034 0.0063 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0543 0.1716
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0066 0.0231 0.0231
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Entamoeba histolytica calcium-binding protein, putative 0.0093 0.0371 0.0875
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0097 0.0097
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0093 0.0371 0.0467
Brugia malayi Papain family cysteine protease containing protein 0.0455 0.2267 0.2267
Echinococcus granulosus cathepsin l1 0.0575 0.2897 0.2897
Brugia malayi cathepsin L-like cysteine proteinase 0.0197 0.0917 0.0917
Echinococcus multilocularis geminin 0.0169 0.0769 0.0769
Loa Loa (eye worm) hypothetical protein 0.0089 0.035 0.035
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0118 0.0502 0.1585
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0086 0.0331 0.0331
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 0.2897 0.6821
Schistosoma mansoni calpain (C02 family) 0.0586 0.2956 0.2956
Entamoeba histolytica calpain family cysteine protease, putative 0.0176 0.0806 0.1899
Plasmodium vivax histone deacetylase, putative 0.0043 0.0108 0.0241
Echinococcus granulosus calpain 5 0.0586 0.2956 0.2956
Plasmodium falciparum histone deacetylase 1 0.0089 0.035 0.0811
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0417 0.2068 0.2068
Entamoeba histolytica prolyl oligopeptidase family protein 0.0185 0.0853 0.2008
Brugia malayi cathepsin L precursor 0.0197 0.0917 0.0917
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0093 0.0371 0.0875
Brugia malayi Cytochrome P450 family protein 0.0042 0.0105 0.0105
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0007 0.0007
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0133 0.058 0.058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0197 0.0917 0.2159
Entamoeba histolytica grainin 2 0.0093 0.0371 0.0875
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0041 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Schistosoma mansoni cpg binding protein 0.003 0.0039 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0362 0.0362
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.035 0.0824
Loa Loa (eye worm) hypothetical protein 0.1513 0.7817 0.7817
Toxoplasma gondii preprocathepsin c precursor, putative 0.0197 0.0917 0.1173
Echinococcus multilocularis cathepsin b 0.193 1 1
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Brugia malayi follicle stimulating hormone receptor 0.0236 0.1122 0.1122
Echinococcus multilocularis calpain 0.0586 0.2956 0.2956
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Loa Loa (eye worm) hypothetical protein 0.0185 0.0853 0.0853
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0097 0.0097
Trypanosoma cruzi 20S proteasome subunit 0.0041 0.0098 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0034 0.0063 0.0149
Giardia lamblia Fructose-bisphosphate aldolase 0.0242 0.115 0.3086
Brugia malayi hypothetical protein 0.0061 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.1378 0.7106 0.7106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Trypanosoma brucei Calpain-like protein 1.1 0.0176 0.0806 0.1024
Echinococcus granulosus calpain A 0.1649 0.8527 0.8527
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.062 0.3131 1
Leishmania major cytochrome p450-like protein 0.0042 0.0105 0.0126
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Toxoplasma gondii kringle domain-containing protein 0.0024 0.0006 0.0008
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0093 0.0371 0.0467
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0006 0.0006
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0378 0.0378
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.0543 0.0543
Brugia malayi EF hand family protein 0.0093 0.0371 0.0371
Giardia lamblia Cathepsin B precursor 0.0197 0.0917 0.2461
Giardia lamblia Cathepsin B precursor 0.0733 0.3726 1
Trypanosoma brucei centrin-3 0.0093 0.0371 0.0467
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0733 0.3726 0.3726
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.0543 0.0543
Brugia malayi beta-lactamase family protein 0.0035 0.0066 0.0066
Echinococcus multilocularis calpain A 0.1649 0.8527 0.8527
Mycobacterium tuberculosis Hypothetical protein 0.0544 0.2733 0.3986
Echinococcus granulosus proteasome prosome macropain 0.0086 0.0331 0.0331
Giardia lamblia Alanyl dipeptidyl peptidase 0.0185 0.0853 0.2289
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0833 0.4248 1
Trypanosoma brucei calmodulin, putative 0.0095 0.038 0.0478
Echinococcus multilocularis ubiquitin specific protease 41 0.0048 0.0132 0.0132
Trypanosoma cruzi centrin, putative 0.0093 0.0371 0.0371
Giardia lamblia Cysteine protease 0.0197 0.0917 0.2461
Brugia malayi Histone deacetylase family protein 0.01 0.0408 0.0408
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0175 0.0224
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0041 0.0098 0.0098
Trypanosoma brucei calpain-like protein, putative 0.0586 0.2956 0.3776
Schistosoma mansoni hypothetical protein 0.0169 0.0769 0.0769
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0543 0.1716
Schistosoma mansoni glycogen phosphorylase 0.0107 0.0443 0.0443
Echinococcus granulosus inhibitor of apoptosis protein 0.0133 0.058 0.058
Onchocerca volvulus 0.0833 0.4248 0.5434
Echinococcus granulosus microtubule associated protein 2 0.1456 0.7519 0.7519
Leishmania major cathepsin L-like protease 0.0933 0.4774 0.6105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0048 0.0132 0.0311
Schistosoma mansoni tar DNA-binding protein 0.0043 0.011 0.011
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0132 0.0161
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0378 0.0378
Trypanosoma brucei calmodulin, putative 0.0093 0.0371 0.0467
Trichomonas vaginalis alpha-glucosidase, putative 0.0034 0.0063 0.0149
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0185 0.0853 0.1091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Trypanosoma cruzi centrin, putative 0.0093 0.0371 0.0371
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0362 0.0362
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0281 0.1354 0.1354
Echinococcus granulosus calumenin 0.0095 0.038 0.038
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0118 0.0502 0.0724
Schistosoma mansoni cpg binding protein 0.0028 0.0031 0.0031
Trichomonas vaginalis calmodulin-2, putative 0.0093 0.0371 0.0875
Trypanosoma brucei histone deacetylase 2 0.0043 0.0108 0.013
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0185 0.0435
Giardia lamblia Hypothetical protein 0.0095 0.038 0.102
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0733 0.3726 0.3726
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.035 0.0824
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0586 0.2956 0.2956
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0034 0.0063 0.0063
Echinococcus multilocularis cathepsin b 0.193 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Trypanosoma brucei Calpain-like protein CALP1.3 0.0176 0.0806 0.1024
Echinococcus multilocularis cysteine protease 0.0833 0.4248 0.4248
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.062 0.3131 0.3131
Entamoeba histolytica prolyl oligopeptidase family protein 0.0185 0.0853 0.2008
Loa Loa (eye worm) hypothetical protein 0.0575 0.2897 0.2897
Echinococcus multilocularis calcium uptake protein 1 0.0095 0.038 0.038
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1513 0.7817 0.7817
Leishmania major cathepsin L-like protease 0.0933 0.4774 0.6105
Giardia lamblia Cathepsin B precursor 0.0197 0.0917 0.2461
Brugia malayi Cytochrome P450 family protein 0.0087 0.0341 0.0341
Giardia lamblia Hypothetical protein 0.0197 0.0917 0.2461
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0176 0.0806 0.1899
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0097 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0066 0.0066
Echinococcus multilocularis histone deacetylase 3 0.0089 0.035 0.035
Echinococcus granulosus cathepsin l cysteine peptidase 0.0833 0.4248 0.4248
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0066 0.0155
Entamoeba histolytica histone deacetylase, putative 0.0089 0.035 0.0824
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Echinococcus multilocularis microtubule associated protein 2 0.1456 0.7519 0.7519
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0132 0.0311
Echinococcus granulosus chromobox protein 1 0.0058 0.0185 0.0185
Brugia malayi Histone deacetylase 1 0.0089 0.035 0.035
Leishmania major hypothetical protein, unknown function 0.0176 0.0806 0.1025
Echinococcus granulosus programmed cell death protein 0.0093 0.0371 0.0371
Leishmania major phospholipase c-like protein 0.0093 0.0371 0.0468
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0197 0.0917 0.0917
Brugia malayi histone deacetylase 11 0.0043 0.0108 0.0108
Schistosoma mansoni rab 0.0093 0.0371 0.0371
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0176 0.0806 0.1899
Onchocerca volvulus Histone deacetylase 10 homolog 0.0043 0.0108 0.0138
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0049 0.0138 0.0138
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0025 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0061 0.0202 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0917 0.0917
Echinococcus granulosus ubiquitin specific protease 41 0.0048 0.0132 0.0132
Echinococcus multilocularis programmed cell death protein 0.0093 0.0371 0.0371
Loa Loa (eye worm) RNA binding protein 0.0043 0.011 0.011
Brugia malayi calpain 5 0.041 0.2032 0.2032
Brugia malayi beta-lactamase 0.0035 0.0066 0.0066
Toxoplasma gondii cathepsin CPC1 0.0197 0.0917 0.1173
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0125 0.0294
Mycobacterium ulcerans lipase LipD 0.0035 0.0066 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0097 0.0229
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0097 0.0097
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.2956
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0034 0.0063 0.0063
Echinococcus granulosus neuronal calcium sensor 0.0093 0.0371 0.0371
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0197 0.0917 0.0917
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0176 0.0806 0.0806
Giardia lamblia Alanyl dipeptidyl peptidase 0.0185 0.0853 0.2289
Loa Loa (eye worm) hypothetical protein 0.0041 0.0097 0.0097
Trypanosoma brucei histone deacetylase 4 0.01 0.0408 0.0513
Echinococcus granulosus caspase 2 0.0061 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0041 0.0097 0.0097
Entamoeba histolytica cysteine proteinase, putative 0.0833 0.4248 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0586 0.2956 0.3776
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Onchocerca volvulus 0.0833 0.4248 0.5434
Loa Loa (eye worm) hypothetical protein 0.1144 0.588 0.588
Schistosoma mansoni cathepsin C 0.0197 0.0917 0.0917
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0093 0.0371 0.0371
Trypanosoma brucei Calpain-like protein 2 0.0176 0.0806 0.1024
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Leishmania major hypothetical protein, conserved 0.0095 0.038 0.0479
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.3777
Trypanosoma cruzi cysteine peptidase, putative 0.0933 0.4774 0.4774
Schistosoma mansoni calpain C (C02 family) 0.0586 0.2956 0.2956
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0066
Plasmodium falciparum serine repeat antigen 6 0.0197 0.0917 0.2148
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.0853 0.0853
Echinococcus multilocularis expressed protein 0.0797 0.4059 0.4059
Brugia malayi calpain family protein 1 0.1554 0.8029 0.8029
Onchocerca volvulus 0.0034 0.0063 0.0081
Trypanosoma brucei caltractin, putative 0.0093 0.0371 0.0467
Echinococcus multilocularis calpain 5 0.0586 0.2956 0.2956
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0097 0.0097
Leishmania major centrin, putative 0.0093 0.0371 0.0468
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0146 0.0146
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Schistosoma mansoni reticulocalbin 0.0095 0.038 0.038
Loa Loa (eye worm) beta-lactamase 0.0035 0.0066 0.0066
Schistosoma mansoni memapsin-2 (A01 family) 0.0444 0.2211 0.2211
Mycobacterium ulcerans hypothetical protein 0.0034 0.0063 0.0181
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0195 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0258 0.1233 0.1233
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0002 0.0006
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0097 0.0097
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0133 0.058 0.058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0066 0.019
Echinococcus multilocularis histone deacetylase 8 0.0043 0.0108 0.0108
Echinococcus granulosus calpain A 0.0586 0.2956 0.2956
Trypanosoma cruzi cruzipain precursor, putative 0.0933 0.4774 0.4774
Loa Loa (eye worm) hypothetical protein 0.0185 0.0853 0.0853
Toxoplasma gondii histone deacetylase HDAC4 0.0043 0.0108 0.0138
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0197 0.0917 0.2461
Echinococcus multilocularis glycogen phosphorylase 0.0107 0.0443 0.0443
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0455 0.2267 0.2267
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Echinococcus multilocularis programmed cell death protein 0.0093 0.0371 0.0371
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0066 0.0087
Loa Loa (eye worm) histone deacetylase 3 0.0089 0.035 0.035
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0176 0.0806 0.0806
Plasmodium falciparum serine repeat antigen 5 0.0197 0.0917 0.2148
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.021 0.021
Echinococcus multilocularis cysteine protease 0.0833 0.4248 0.4248
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Onchocerca volvulus Cathepsin L homolog 0.0833 0.4248 0.5434
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0185 0.0435
Echinococcus multilocularis histone deacetylase 6 0.01 0.0408 0.0408
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0197 0.0917 0.2159
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.193 1 1
Mycobacterium ulcerans hypothetical protein 0.0035 0.0066 0.019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0034 0.0063 0.0149
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.3777
Trypanosoma brucei calpain-like protein, putative 0.0586 0.2956 0.3776
Plasmodium vivax histone deacetylase, putative 0.01 0.0408 0.0947
Echinococcus multilocularis calumenin 0.0095 0.038 0.038
Trichomonas vaginalis calcium binding proteins, putative 0.0093 0.0371 0.0875
Brugia malayi prolyl oligopeptidase family protein 0.0527 0.2647 0.2647
Brugia malayi calpain 7 0.0586 0.2956 0.2956
Trypanosoma brucei histone deacetylase 3 0.01 0.0408 0.0513
Echinococcus multilocularis calmodulin 0.0093 0.0371 0.0371
Schistosoma mansoni cathepsin B (C01 family) 0.0197 0.0917 0.0917
Schistosoma mansoni calpain-2 (C02 family) 0.0176 0.0806 0.0806
Trypanosoma cruzi histone deacetylase, putative 0.0043 0.0108 0.0108
Giardia lamblia Cathepsin L precursor 0.0197 0.0917 0.2461
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0197 0.0917 0.2148
Echinococcus granulosus expressed protein 0.0797 0.4059 0.4059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.021 0.021
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0202 0.0202
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.3777
Loa Loa (eye worm) hypothetical protein 0.0133 0.058 0.058
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0066 0.0087
Trypanosoma cruzi cysteine peptidase, putative 0.0258 0.1233 0.1233
Trypanosoma cruzi cysteine peptidase, putative 0.0833 0.4248 0.4248
Leishmania major calpain family cysteine protease-like protein 0.0176 0.0806 0.1025
Leishmania major hypothetical protein, conserved 0.0093 0.0371 0.0468
Schistosoma mansoni tar DNA-binding protein 0.0043 0.011 0.011
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0176 0.0806 0.0806
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0097 0.0097
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Giardia lamblia Cysteine protease 0.0197 0.0917 0.2461
Echinococcus multilocularis lysosomal alpha glucosidase 0.0155 0.0697 0.0697
Echinococcus granulosus lysine specific demethylase 5A 0.005 0.0146 0.0146
Loa Loa (eye worm) TAR-binding protein 0.0043 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Echinococcus granulosus prolyl endopeptidase 0.1513 0.7817 0.7817
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0197 0.0917 0.2148
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0833 0.4248 1
Brugia malayi hypothetical protein 0.0041 0.0097 0.0097
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0097 0.0097
Trypanosoma brucei Component of motile flagella 41 0.0093 0.0371 0.0467
Echinococcus granulosus Mastin 0.0034 0.0063 0.0063
Echinococcus granulosus Glycosyl transferase family 35 0.0107 0.0443 0.0443
Schistosoma mansoni calmodulin 0.0093 0.0371 0.0371
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Onchocerca volvulus 0.005 0.0146 0.0187
Plasmodium falciparum serine repeat antigen 2 0.0197 0.0917 0.2148
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0133 0.058 0.058
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0408 0.0408
Schistosoma mansoni cathepsin F (C01 family) 0.0833 0.4248 0.4248
Trichomonas vaginalis calcium binding protein, putative 0.0093 0.0371 0.0875
Loa Loa (eye worm) hypothetical protein 0.0043 0.0108 0.0108
Echinococcus multilocularis acylamino acid releasing enzyme 0.0185 0.0853 0.0853
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0125 0.0294
Entamoeba histolytica cysteine proteinase, putative 0.0455 0.2267 0.5338
Loa Loa (eye worm) ctsf protein 0.0833 0.4248 0.4248
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0097 0.0097
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0146 0.0146
Leishmania major protein kinase, putative 0.0093 0.0371 0.0468
Echinococcus granulosus calmodulin 0.0093 0.0371 0.0371
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Giardia lamblia Cathepsin B precursor 0.0197 0.0917 0.2461
Schistosoma mansoni neuronal calcium sensor 0.0093 0.0371 0.0371
Schistosoma mansoni histone deacetylase 0.0089 0.035 0.035
Trichomonas vaginalis centrin, putative 0.0093 0.0371 0.0875
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0066 0.0231 0.0231
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Plasmodium vivax histone deacetylase 1, putative 0.0089 0.035 0.0811
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0197 0.0917 0.2159
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0197 0.0917 0.2148
Entamoeba histolytica cysteine protease, putative 0.0197 0.0917 0.2159
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0097 0.0097
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0586 0.2956 0.2956
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.035 0.035
Onchocerca volvulus Prolyl endopeptidase homolog 0.1513 0.7817 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0105 0.0105
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0097 0.0097
Mycobacterium leprae Conserved hypothetical protein 0.0544 0.2733 0.8727
Trypanosoma brucei mitochondrial calcium uptake 1 0.0093 0.0371 0.0467
Brugia malayi Calmodulin-like protein 0.0093 0.0371 0.0371
Schistosoma mansoni inhibitor of apoptosis protein 0.0133 0.058 0.058
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0176 0.0806 0.1899
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0097 0.0097
Plasmodium vivax hypothetical protein, conserved 0.0095 0.038 0.0882
Plasmodium vivax unspecified product 0.0258 0.1233 0.2892
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0132 0.0311
Plasmodium vivax vivapain-2 0.0833 0.4248 1
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0066 0.0231 0.0288
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Loa Loa (eye worm) cathepsin B 0.0733 0.3726 0.3726
Entamoeba histolytica hypothetical protein 0.0041 0.0097 0.0229
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Giardia lamblia Cathepsin B precursor 0.0197 0.0917 0.2461
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1647 0.8518 0.8518
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0197 0.0917 0.0917
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0185 0.0853 0.0853
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Loa Loa (eye worm) calmodulin-like protein 0.0093 0.0371 0.0371
Echinococcus granulosus dnaJ subfamily B 0.0402 0.1992 0.1992
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0197 0.0917 0.2159
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0089 0.035 0.0824
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0185 0.0853 0.2008
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0097 0.0097
Echinococcus granulosus cathepsin b 0.193 1 1
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Leishmania major centrin, putative,caltractin, putative 0.0093 0.0371 0.0468
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0097 0.0097
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0066 0.0231 0.0231
Schistosoma mansoni neuronal calcium sensor 0.0093 0.0371 0.0371
Plasmodium falciparum cysteine proteinase falcipain 3 0.0833 0.4248 1
Brugia malayi Trypsin family protein 0.0034 0.0063 0.0063
Echinococcus multilocularis tumor protein p63 0.0356 0.1752 0.1752
Giardia lamblia Cathepsin B precursor 0.0733 0.3726 1
Brugia malayi MH2 domain containing protein 0.0127 0.0548 0.0548
Brugia malayi sulfakinin receptor protein 0.0347 0.1704 0.1704
Trypanosoma brucei prolyl endopeptidase 0.1513 0.7817 1
Trypanosoma brucei cysteine peptidase, putative 0.0176 0.0806 0.1024
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0527 0.2647 0.2647
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0097 0.0097
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0097 0.0097
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Schistosoma mansoni alpha-glucosidase 0.0134 0.0584 0.0584
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.021 0.021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0176 0.0806 0.0806
Chlamydia trachomatis glycogen phosphorylase 0.0107 0.0443 0.5
Trichomonas vaginalis calpain, putative 0.0176 0.0806 0.1899
Trichomonas vaginalis hypothetical protein 0.0176 0.0806 0.1899
Trypanosoma cruzi I/6 autoantigen, putative 0.0093 0.0371 0.0371
Trichomonas vaginalis calcium binding protein, putative 0.0093 0.0371 0.0875
Trichomonas vaginalis set domain proteins, putative 0.0492 0.2461 0.5795
Loa Loa (eye worm) EF hand family protein 0.0093 0.0371 0.0371
Entamoeba histolytica calpain large subunit domain III containing protein 0.041 0.2032 0.4783
Trypanosoma cruzi kinesin, putative 0.041 0.2032 0.2032
Brugia malayi Protein kinase domain containing protein 0.0024 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0066 0.0066
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0408 0.0408
Onchocerca volvulus 0.0035 0.0066 0.0084
Plasmodium vivax vivapain-2 0.0833 0.4248 1
Loa Loa (eye worm) calpain family protein 1 0.1554 0.8029 0.8029
Schistosoma mansoni hypothetical protein 0.0093 0.0371 0.0371
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.062 0.3131 0.3131
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0066 0.019
Schistosoma mansoni ef hand domain family member A2 0.0093 0.0371 0.0371
Leishmania major calmodulin, putative 0.0093 0.0371 0.0468
Trichomonas vaginalis calpain, putative 0.0176 0.0806 0.1899
Trypanosoma brucei hypothetical protein 0.0176 0.0806 0.1024
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0176 0.0806 0.0806
Brugia malayi Papain family cysteine protease containing protein 0.0197 0.0917 0.0917
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.0543 0.0543
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0209 0.0209
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0093 0.0371 0.0371
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0833 0.4248 0.4248
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0575 0.2897 0.2897
Leishmania major histone deacetylase, putative 0.01 0.0408 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0043 0.011 0.011
Brugia malayi PXA domain containing protein 0.0041 0.0097 0.0097
Echinococcus granulosus histone deacetylase 6 0.01 0.0408 0.0408
Mycobacterium tuberculosis Probable peptidase 0.062 0.3131 0.4568
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Leishmania major cathepsin L-like protease 0.0833 0.4248 0.5431
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0455 0.2267 0.5338
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0176 0.0806 0.1899
Entamoeba histolytica cysteine proteinase, putative 0.0455 0.2267 0.5338
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0086 0.0331 0.0415
Entamoeba histolytica calmodulin, putative 0.0093 0.0371 0.0875
Echinococcus multilocularis EF hand domain containing family member A2 0.0095 0.038 0.038
Echinococcus granulosus EF hand domain containing family member A2 0.0095 0.038 0.038
Entamoeba histolytica cysteine protease, putative 0.0833 0.4248 1
Giardia lamblia Encystation-specific protease 0.0197 0.0917 0.2461
Schistosoma mansoni neuronal calcium sensor 0.0093 0.0371 0.0371
Echinococcus granulosus enteropeptidase 0.0034 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0371 0.0875
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.0543 0.0694
Leishmania major alpha glucosidase II subunit, putative 0.0034 0.0063 0.0074
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0034 0.0063 0.0149
Giardia lamblia Cathepsin L precursor 0.0197 0.0917 0.2461
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0432 0.2149 0.2149
Onchocerca volvulus 0.0095 0.038 0.0486
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0034 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0197 0.0917 0.2159
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0917 0.0917
Schistosoma mansoni hypothetical protein 0.0169 0.0769 0.0769
Onchocerca volvulus 0.0093 0.0371 0.0475
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0833 0.4248 0.4248
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Loa Loa (eye worm) glutaminase 0.0261 0.125 0.125
Loa Loa (eye worm) histone deacetylase 11 0.0043 0.0108 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.0853 0.0853
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Trypanosoma brucei cysteine peptidase C (CPC) 0.0733 0.3726 0.4763
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.062 0.3131 0.4568
Schistosoma mansoni hypothetical protein 0.0133 0.058 0.058
Trichomonas vaginalis calmodulin, putative 0.0093 0.0371 0.0875
Trichomonas vaginalis histone deacetylase, putative 0.0089 0.035 0.0824
Loa Loa (eye worm) hypothetical protein 0.0197 0.0917 0.0917
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0007 0.0007
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Plasmodium vivax serine-repeat antigen (SERA) 0.0197 0.0917 0.2148
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0041 0.0098 0.0232
Loa Loa (eye worm) calpain 5 0.041 0.2032 0.2032
Onchocerca volvulus 0.0034 0.0063 0.0081
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0049 0.0138 0.0138
Mycobacterium tuberculosis Conserved hypothetical protein 0.0544 0.2733 0.3986
Echinococcus granulosus neurocalcin 0.0093 0.0371 0.0371
Brugia malayi cathepsin Z-like cysteine proteinase 0.0197 0.0917 0.0917
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0097 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0455 0.2267 0.2895
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.021 0.0269
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0236 0.1122 0.1122
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0034 0.0063 0.0063
Plasmodium falciparum serine repeat antigen 1 0.0197 0.0917 0.2148
Schistosoma mansoni gamma-secretase subunit aph-1 0.0243 0.1154 0.1154
Plasmodium vivax SET domain protein, putative 0.0063 0.021 0.0482
Leishmania major programmed cell death 6 protein-like protein 0.0093 0.0371 0.0468
Echinococcus granulosus cathepsin L cysteine protease 0.0455 0.2267 0.2267
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0048 0.0132 0.0311
Brugia malayi chromobox protein homolog 3 0.0032 0.0052 0.0052
Plasmodium vivax vivapain-1 0.0455 0.2267 0.5331
Leishmania major hypothetical protein, conserved 0.0035 0.0066 0.0077
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0586 0.2956 0.2956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0197 0.0917 0.0917
Schistosoma mansoni alpha glucosidase 0.0034 0.0063 0.0063
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0675 0.3424 0.3424
Brugia malayi glutaminase DH11.1 0.0261 0.125 0.125
Entamoeba histolytica cysteine protease, putative 0.0197 0.0917 0.2159
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.193 1 1
Entamoeba histolytica glycogen phosphorylase, putative 0.0107 0.0443 0.1042
Schistosoma mansoni glycogen phosphorylase 0.0107 0.0443 0.0443
Brugia malayi cytochrome P450 0.0024 0.0007 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.021 0.021
Trichomonas vaginalis myosin light chain 1, putative 0.0093 0.0371 0.0875
Giardia lamblia Histone deacetylase 0.0089 0.035 0.0939
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0041 0.0098 0.0118
Trypanosoma brucei antigen, putative 0.0586 0.2956 0.3776
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0066 0.0087
Mycobacterium ulcerans hypothetical protein 0.0544 0.2733 0.8727
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0125 0.0173
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0176 0.0806 0.1024
Brugia malayi jmjC domain containing protein 0.005 0.0146 0.0146
Onchocerca volvulus Deterin homolog 0.0133 0.058 0.0742
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0197 0.0917 0.2159
Trichomonas vaginalis glutaminase, putative 0.0261 0.125 0.2942
Echinococcus granulosus survival motor neuron protein 1 0.0246 0.1175 0.1175
Brugia malayi cathepsin F-like cysteine proteinase 0.0197 0.0917 0.0917
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0371 0.0875
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0176 0.0806 0.1024
Loa Loa (eye worm) hypothetical protein 0.0048 0.0132 0.0132
Onchocerca volvulus 0.0034 0.0063 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0048 0.0132 0.0132
Brugia malayi cathepsin L-like precursor 0.0575 0.2897 0.2897
Onchocerca volvulus Cathepsin F homolog 0.0833 0.4248 0.5434
Schistosoma mansoni cathepsin s 0.0258 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0061 0.0202 0.0202
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0243 0.1154 0.1154
Toxoplasma gondii troponin c, isotype gamma, putative 0.0093 0.0371 0.0475
Trypanosoma cruzi cysteine peptidase, putative 0.0933 0.4774 0.4774
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0066 0.0087
Trichomonas vaginalis calmodulin, putative 0.0095 0.038 0.0895
Toxoplasma gondii calcium-dependent protein kinase 0.0095 0.038 0.0486
Brugia malayi Cathepsin L-like cysteine proteinase 0.0575 0.2897 0.2897
Echinococcus granulosus histone deacetylase 1 0.0089 0.035 0.035
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0066 0.0066
Echinococcus granulosus glycogen phosphorylase 0.0107 0.0443 0.0443
Schistosoma mansoni glutaminase 0.0261 0.125 0.125
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0066
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0197 0.0917 0.2148
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0362 0.0362
Giardia lamblia Cysteine protease 0.0197 0.0917 0.2461
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0041 0.0098 0.0098
Toxoplasma gondii cathepsin B 0.0733 0.3726 0.4767
Brugia malayi histone deacetylase 3 (HD3) 0.0089 0.035 0.035
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.0543 0.1716
Trypanosoma cruzi histone deacetylase 1, putative 0.0089 0.035 0.035
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0048 0.0132 0.0132
Echinococcus multilocularis chromobox protein 1 0.0058 0.0185 0.0185
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0066 0.0155
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0066 0.0087
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0063
Giardia lamblia Cathepsin B precursor 0.0197 0.0917 0.2461
Toxoplasma gondii EFHC1, putative 0.0093 0.0371 0.0475
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0197 0.0917 0.2148
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0362 0.0362
Brugia malayi calpain D 0.0176 0.0806 0.0806
Toxoplasma gondii cathepsin CPL 0.0833 0.4248 0.5434
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0093 0.0371 0.0371
Trypanosoma cruzi oligopeptidase b 0.062 0.3131 0.3131
Trypanosoma cruzi cruzipain precursor, putative 0.0258 0.1233 0.1233
Trypanosoma cruzi calmodulin, putative 0.0093 0.0371 0.0371
Loa Loa (eye worm) heterochromatin protein 1 0.0058 0.0185 0.0185
Schistosoma mansoni jumonji domain containing protein 0.0049 0.0138 0.0138
Toxoplasma gondii proteasome subunit beta type, putative 0.0086 0.0331 0.0424
Toxoplasma gondii EF hand domain-containing protein 0.0093 0.0371 0.0475
Brugia malayi hypothetical protein 0.0041 0.0097 0.0097
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.0806
Leishmania major proteasome beta 5 subunit, putative 0.0086 0.0331 0.0416
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Leishmania major oligopeptidase b 0.062 0.3131 0.4001
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0097 0.0229
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0176 0.0806 0.1899
Onchocerca volvulus 0.0833 0.4248 0.5434
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0052 0.0122
Trypanosoma cruzi oligopeptidase b 0.062 0.3131 0.3131
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0086 0.0331 0.0331
Schistosoma mansoni cercarial elastase (S01 family) 0.0034 0.0063 0.0063
Echinococcus multilocularis histone deacetylase 6 0.0106 0.044 0.044
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.021 0.021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0242 0.115 0.2707
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0197 0.0917 0.2148
Leishmania major hypothetical protein, conserved 0.0176 0.0806 0.1025
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0086 0.0331 0.0331
Schistosoma mansoni cytochrome P450 0.0024 0.0007 0.0007
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0527 0.2647 0.2647
Leishmania major kinesin, putative 0.041 0.2032 0.2594
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0455 0.2267 0.2895
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0066 0.0066
Echinococcus granulosus cathepsin l1 0.0833 0.4248 0.4248
Entamoeba histolytica cysteine protease, putative 0.0197 0.0917 0.2159
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0176 0.0806 0.0806
Trypanosoma brucei centrin, putative 0.0093 0.0371 0.0467
Entamoeba histolytica calmodulin, putative 0.0093 0.0371 0.0875
Plasmodium falciparum proteasome subunit beta type-5 0.0086 0.0331 0.0767
Onchocerca volvulus 0.009 0.0354 0.0453
Brugia malayi cathepsin Z-like cysteine proteinase 0.0197 0.0917 0.0917
Schistosoma mansoni neuronal calcium sensor 0.0093 0.0371 0.0371
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0281 0.1354 0.1725
Echinococcus multilocularis cpg binding protein 0.003 0.0039 0.0039
Onchocerca volvulus 0.0034 0.0063 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Leishmania major cysteine peptidase A (CPA) 0.0833 0.4248 0.5431
Echinococcus granulosus cathepsin L 0.0455 0.2267 0.2267
Trichomonas vaginalis calcium binding protein, putative 0.0093 0.0371 0.0875
Giardia lamblia Cathepsin L precursor 0.0197 0.0917 0.2461
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.193 1 1
Giardia lamblia Transglutaminase/protease, putative 0.0544 0.2733 0.7334
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0093 0.0371 0.0371
Giardia lamblia Cathepsin L-like protease 0.0197 0.0917 0.2461
Brugia malayi PXA domain containing protein 0.0041 0.0097 0.0097
Brugia malayi prolyl oligopeptidase family protein 0.1513 0.7817 0.7817
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0118 0.0502 0.1585
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0093 0.0371 0.0875
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0093 0.0371 0.0371
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0086 0.0331 0.0779
Loa Loa (eye worm) calpain 0.0586 0.2956 0.2956
Plasmodium vivax centrin-1, putative 0.0093 0.0371 0.0862
Onchocerca volvulus 0.0833 0.4248 0.5434
Brugia malayi Papain family cysteine protease containing protein 0.0833 0.4248 0.4248
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0527 0.2647 0.2647
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0917 0.2159
Schistosoma mansoni histone deacetylase 0.0089 0.035 0.035
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0176 0.0806 0.1025
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.0543 0.0687
Leishmania major calmodulin-like protein 0.0093 0.0371 0.0468
Entamoeba histolytica cysteine protease, putative 0.0455 0.2267 0.5338
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0034 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0933 0.4774 0.6104
Onchocerca volvulus 0.0034 0.0063 0.0081
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0093 0.0371 0.0371
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0097 0.0097
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0197 0.0917 0.2148
Loa Loa (eye worm) hypothetical protein 0.0159 0.0718 0.0718
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.062 0.3131 1
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0007 0.0007
Schistosoma mansoni chromobox protein 0.0058 0.0185 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0833 0.4248 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0097 0.0229
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0048 0.0132 0.0162
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0586 0.2956 0.2956
Leishmania major cathepsin L-like protease 0.0833 0.4248 0.5431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0833 0.4248 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0197 0.0917 0.2159
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0065 0.0153
Brugia malayi CXXC zinc finger family protein 0.0028 0.0031 0.0031
Brugia malayi hypothetical protein 0.0347 0.1704 0.1704
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0548 0.0548

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 3.981071706 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 7.943282347 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 12.58925412 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (ADMET) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ] ChEMBL. No reference
Potency (ADMET) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Hemoglobin Beta Chain Splicing. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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