Detailed information for compound 1880630

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2215.74 | Formula: C68H86Na16O43S8
  • H donors: 16 H acceptors: 32 LogP: 0.07 Rotable bonds: 76
    Rule of 5 violations (Lipinski): 3
  • SMILES: [O-]C(=O)CC(C(=O)[O-])SCCCO[C@H]1[C@H](O[C@@H]2O[C@H](COCCCSC(C(=O)[O-])CC(=O)[O-])[C@H]([C@@H]([C@H]2OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-])[C@@H](COCCCSC(C(=O)[O-])CC(=O)[O-])O[C@@H]([C@@H]1OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
  • InChi: 1S/C68H102O43S8.16Na/c69-45(70)25-37(59(85)86)112-17-1-9-101-33-35-53(103-11-3-19-114-39(61(89)90)27-47(73)74)55(104-12-4-20-115-40(62(91)92)28-48(75)76)58(107-15-7-23-118-43(65(97)98)31-51(81)82)68(110-35)111-54-36(34-102-10-2-18-113-38(60(87)88)26-46(71)72)109-67(108-16-8-24-119-44(66(99)100)32-52(83)84)57(106-14-6-22-117-42(64(95)96)30-50(79)80)56(54)105-13-5-21-116-41(63(93)94)29-49(77)78;;;;;;;;;;;;;;;;/h35-44,53-58,67-68H,1-34H2,(H,69,70)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)(H,83,84)(H,85,86)(H,87,88)(H,89,90)(H,91,92)(H,93,94)(H,95,96)(H,97,98)(H,99,100);;;;;;;;;;;;;;;;/q;16*+1/p-16/t35-,36-,37?,38?,39?,40?,41?,42?,43?,44?,53-,54-,55+,56+,57-,58-,67+,68+;;;;;;;;;;;;;;;;/m1................/s1
  • InChiKey: OOOQDKWTWZWMMG-NAOGELEPSA-A  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0019 0.0021
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0032 0.0016
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Loa Loa (eye worm) fibroinase 0.2426 0.5188 0.5639
Brugia malayi hypothetical protein 0.0064 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0235 0.0461 0.0501
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.2168
Mycobacterium tuberculosis Conserved protein 0.0251 0.0496 0.0481
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0024 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0682 0.0733
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0094 0.0103
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0092 0.0169
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Loa Loa (eye worm) hypothetical protein 0.0345 0.0699 0.0759
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0542 0.1123 0.2152
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0024 0.0047
Brugia malayi Cathepsin L-like cysteine proteinase 0.1662 0.354 0.3847
Echinococcus granulosus histone deacetylase 6 0.0099 0.0167 0.0167
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0167 0.0182
Leishmania major hypothetical protein, conserved 0.0045 0.005 0.0072
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Trypanosoma cruzi cysteine peptidase, putative 0.1306 0.2771 0.3005
Brugia malayi Calmodulin-like protein 0.0116 0.0204 0.0221
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0037 0.0033 0.003
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Plasmodium falciparum serine repeat antigen 4 0.0542 0.1123 0.2152
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0032 0.0016
Leishmania major receptor-type adenylate cyclase a-like protein 0.0208 0.0403 0.0694
Schistosoma mansoni chromatin regulatory protein sir2 0.0138 0.0251 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi hypothetical protein 0.004 0.0039 0.0042
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0276 0.0295
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0045 0.0045
Echinococcus multilocularis EF hand domain containing family member A2 0.0118 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0028 0.0016
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Echinococcus multilocularis cysteine protease 0.2426 0.5188 0.5188
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0542 0.1123 0.2152
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0057 0.0093
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Leishmania major pyruvate kinase 0.0033 0.0024 0.0028
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0216 0.02
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.026
Leishmania major pyruvate kinase 0.0033 0.0024 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4285 0.9202 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0039 0.0042
Brugia malayi Papain family cysteine protease containing protein 0.1306 0.2771 0.3012
Plasmodium vivax histone deacetylase, putative 0.0042 0.0045 0.0071
Onchocerca volvulus 0.0036 0.0032 0.0053
Echinococcus multilocularis centrin 2 0.0116 0.0204 0.0204
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0043 0.0042
Echinococcus granulosus Dipeptidyl peptidase 9 0.057 0.1183 0.1183
Loa Loa (eye worm) hypothetical protein 0.1775 0.3784 0.4112
Brugia malayi Histone deacetylase family protein 0.0099 0.0167 0.0181
Plasmodium falciparum serine repeat antigen 7 0.0542 0.1123 0.2152
Mycobacterium tuberculosis Hypothetical protein 0.0251 0.0496 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.17 0.3622 0.698
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0143 0.0147
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0039 0.0037
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Schistosoma mansoni hypothetical protein 0.0116 0.0204 0.0217
Entamoeba histolytica calpain family cysteine protease, putative 0.0389 0.0793 0.1523
Onchocerca volvulus Legumain homolog 0.0149 0.0276 0.0524
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Mycobacterium ulcerans putative transglutaminase-like protein 0.0251 0.0496 0.0481
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Brugia malayi RNA binding protein 0.0065 0.0094 0.0103
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Trypanosoma cruzi centrin, putative 0.0124 0.0221 0.0232
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0116 0.0204 0.0212
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0138 0.0251 0.0251
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0019 0.0019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0032 0.003
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Plasmodium vivax calpain, putative 0.0944 0.1991 0.3828
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Brugia malayi beta-lactamase family protein 0.0036 0.0032 0.0035
Onchocerca volvulus 0.0036 0.0032 0.0053
Onchocerca volvulus Peroxidase homolog 0.0064 0.0092 0.0169
Echinococcus granulosus histone deacetylase 1 0.0088 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0028 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Brugia malayi Cathepsin L-like precursor 0.1662 0.354 0.3847
Schistosoma mansoni hypothetical protein 0.0037 0.0033 0.003
Echinococcus granulosus axis inhibition protein axin 0.004 0.0039 0.0039
Plasmodium vivax SET domain protein, putative 0.0122 0.0218 0.0404
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0028 0.0049
Echinococcus multilocularis cathepsin L cysteine protease 0.2426 0.5188 0.5188
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0012 0.0013
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0043 0.0038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0516 0.1067 0.1151
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0542 0.1123 0.2152
Plasmodium falciparum pyruvate kinase 0.0033 0.0024 0.0031
Loa Loa (eye worm) hypothetical protein 0.0389 0.0793 0.0861
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0039 0.0042
Trypanosoma cruzi cysteine protease, putative 0.1306 0.2771 0.3005
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0012 0.0013
Schistosoma mansoni hypothetical protein 0.0127 0.0228 0.0243
Entamoeba histolytica cysteine proteinase, putative 0.2426 0.5188 1
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0043 0.0068
Entamoeba histolytica cysteine protease, putative 0.2426 0.5188 1
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0057 0.0057
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0037 0.0033 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Toxoplasma gondii cathepsin CPL 0.2426 0.5188 1
Leishmania major sir2-family protein-like protein 0.0032 0.0023 0.0025
Brugia malayi hypothetical protein 0.0037 0.0033 0.0035
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0028 0.0035
Toxoplasma gondii microneme protein MIC4 0.0029 0.0016 0.0014
Trypanosoma brucei histone deacetylase 2 0.0042 0.0045 0.0064
Brugia malayi Cathepsin L-like precursor 0.0764 0.1601 0.174
Echinococcus granulosus axis inhibition protein axin 0.004 0.0039 0.0039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0019 0.0021
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Echinococcus multilocularis histone deacetylase 0.0099 0.0167 0.0167
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0023 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0083 0.0132 0.0216
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0032 0.0016
Schistosoma mansoni rab 0.0116 0.0204 0.0217
Schistosoma mansoni intermediate filament proteins 0.0027 0.0012 0.0008
Brugia malayi proteasome subunit beta type 1 0.0064 0.0092 0.01
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.1683
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Brugia malayi Papain family cysteine protease containing protein 0.2426 0.5188 0.5639
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0019 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0024 0.0031
Leishmania major phospholipase c-like protein 0.0116 0.0204 0.0343
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0235 0.0461 0.0795
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Echinococcus granulosus histone deacetylase 7 0.0099 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0682 0.0733
Leishmania major protein kinase, putative 0.0116 0.0204 0.0343
Brugia malayi nuclear receptor NHR-88 0.0031 0.0019 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0218 0.0232
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0212
Trypanosoma cruzi cysteine proteinase, putative 0.1306 0.2771 0.3005
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0215 0.02
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0542 0.1123 0.1216
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.17 0.3622 0.393
Brugia malayi calpain D 0.0389 0.0793 0.0861
Trypanosoma brucei trypanothione reductase 0.0048 0.0057 0.0085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0257 0.0257
Brugia malayi Thioredoxin reductase 0.0048 0.0057 0.0062
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.2426 0.5188 0.5639
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0045 0.004
Plasmodium falciparum histone deacetylase, putative 0.0099 0.0167 0.0306
Schistosoma mansoni lamin 0.0027 0.0012 0.0008
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0043 0.0047
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0023 0.0027
Onchocerca volvulus Matrilysin homolog 0.0053 0.0067 0.012
Brugia malayi Papain family cysteine protease containing protein 0.1306 0.2771 0.3012
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0052 0.0094
Leishmania major calmodulin, putative 0.0116 0.0204 0.0343
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0264 0.0524 0.0905
Echinococcus multilocularis pyruvate kinase 0.0033 0.0024 0.0024
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0039 0.0037
Echinococcus multilocularis lamin dm0 0.0027 0.0012 0.0012
Brugia malayi Cytochrome P450 family protein 0.0045 0.0051 0.0055
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Echinococcus multilocularis proteasome (prosome, macropain) 0.0083 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0204 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1662 0.354 0.6824
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0024 0.0017
Schistosoma mansoni lamin 0.0027 0.0012 0.0008
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0023 0.0038
Echinococcus granulosus cathepsin L cysteine protease 0.1306 0.2771 0.2771
Trypanosoma cruzi caltractin, putative 0.0116 0.0204 0.0212
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0143 0.0147
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0114 0.0114
Loa Loa (eye worm) transcriptional regulator 0.0125 0.0222 0.0242
Toxoplasma gondii calmodulin CAM1 0.0118 0.0208 0.0386
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0499 0.0543
Echinococcus granulosus calmodulin 0.0116 0.0204 0.0204
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0294 0.0315
Loa Loa (eye worm) proteasome subunit beta type 2 0.004 0.0039 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0653 0.1363 0.238
Giardia lamblia Hypothetical protein 0.0125 0.0222 0.0555
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0019 0.0019
Loa Loa (eye worm) ctsf protein 0.2426 0.5188 0.5639
Echinococcus multilocularis geminin 0.0509 0.1053 0.1053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Leishmania major histone deacetylase, putative 0.0088 0.0143 0.0237
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0083 0.0132 0.0138
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0567 0.1177 0.1271
Plasmodium falciparum cysteine proteinase falcipain 2a 0.2426 0.5188 1
Trichomonas vaginalis centrin, putative 0.0116 0.0204 0.0393
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.0461 0.0492
Brugia malayi glutathione reductase 0.0048 0.0057 0.0062
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0116 0.0204 0.0204
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0051 0.0056
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0116 0.0204 0.0393
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0051 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0032 0.0059
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Schistosoma mansoni cathepsin F (C01 family) 0.2426 0.5188 0.5636
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Echinococcus multilocularis neuronal calcium sensor 0.0116 0.0204 0.0204
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0039 0.0039
Giardia lamblia Pyruvate kinase 0.0033 0.0024 0.0005
Echinococcus granulosus cathepsin b 0.4285 0.9202 0.9202
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1899 0.4052 0.4398
Schistosoma mansoni axis inhibition protein axin 0.004 0.0039 0.0037
Loa Loa (eye worm) calpain D 0.0389 0.0793 0.0861
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0019 0.0021
Echinococcus granulosus programmed cell death protein 0.0124 0.0221 0.0221
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.4486
Plasmodium falciparum calpain 0.0389 0.0793 0.1514
Echinococcus multilocularis prolyl endopeptidase 0.1651 0.3518 0.3518
Entamoeba histolytica cysteine proteinase, putative 0.1662 0.354 0.6822
Schistosoma mansoni DNA polymerase eta 0.0045 0.0051 0.0051
Trypanosoma brucei unspecified product 0.0208 0.0403 0.0694
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0016 0.0014
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Echinococcus granulosus calbindin 32 0.0118 0.0208 0.0208
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0218 0.0404
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0125 0.0222 0.0376
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0019 0.0019
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Brugia malayi cathepsin L-like precursor 0.1662 0.354 0.3847
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0132 0.0134
Echinococcus granulosus cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Plasmodium falciparum cysteine proteinase falcipain 3 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0143 0.0156
Trypanosoma brucei proteasome beta 6 subunit 0.0064 0.0092 0.0147
Echinococcus multilocularis programmed cell death protein 0.0124 0.0221 0.0221
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0228 0.0228
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0057 0.0062
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0235 0.0461 0.0883
Trypanosoma cruzi cysteine proteinase, putative 0.1306 0.2771 0.3005
Onchocerca volvulus 0.0037 0.0033 0.0054
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Loa Loa (eye worm) hypothetical protein 0.0154 0.0286 0.031
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0542 0.1123 0.3058
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0215 0.0719
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0083 0.0132 0.0303
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0131 0.0236 0.0449
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0138 0.0251 0.0635
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0143 0.0261
Schistosoma mansoni pyruvate kinase 0.0033 0.0024 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0106 0.0182 0.0198
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.2777
Loa Loa (eye worm) hypothetical protein 0.4285 0.9202 1
Onchocerca volvulus Cathepsin F homolog 0.2426 0.5188 1
Brugia malayi calpain 5 0.0389 0.0793 0.0861
Echinococcus granulosus EF hand domain containing family member A2 0.0116 0.0204 0.0204
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0167 0.0167
Leishmania major calmodulin-like protein 0.0116 0.0204 0.0343
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0045 0.0078
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0039 0.0042
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0019 0.0019
Trypanosoma brucei conserved protein 0.0217 0.0423 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0542 0.1123 0.2165
Brugia malayi EF hand family protein 0.0116 0.0204 0.0221
Brugia malayi cathepsin L-like cysteine proteinase 0.0542 0.1123 0.1221
Leishmania major calpain protease-like protein 0.0389 0.0793 0.1378
Schistosoma mansoni peroxidasin 0.0064 0.0092 0.0095
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0039 0.0039
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0039 0.0054
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0064 0.0092 0.0161
Echinococcus multilocularis calpain family protein 1, d 0.1608 0.3425 0.3425
Onchocerca volvulus 0.0029 0.0016 0.0021
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0216 0.0364
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0037 0.0033 0.0035
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0023 0.0027
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.057 0.1183 0.2063
Echinococcus granulosus histone deacetylase 0.0099 0.0167 0.0167
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Plasmodium vivax vivapain-2 0.2426 0.5188 1
Trypanosoma cruzi kinesin, putative 0.0555 0.1152 0.1244
Echinococcus granulosus cathepsin b 0.4285 0.9202 0.9202
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0019 0.0021
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Echinococcus multilocularis pyruvate kinase 0.0026 0.0009 0.0009
Entamoeba histolytica cysteine proteinase 1, putative 0.1306 0.2771 0.5339
Brugia malayi calpain 5 0.0555 0.1152 0.1252
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0389 0.0793 0.1514
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0092 0.0169
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Loa Loa (eye worm) hypothetical protein 0.0116 0.0204 0.0221
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0085 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0039 0.0042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0016 0.0014
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0143 0.0156
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0032 0.0032
Toxoplasma gondii microneme protein, putative 0.0029 0.0016 0.0014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0208 0.0403 0.043
Brugia malayi hypothetical protein 0.004 0.0039 0.0042
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.004 0.0039 0.0033
Loa Loa (eye worm) glycogen phosphorylase 0.0105 0.0181 0.0197
Leishmania major silent information regulator 2, putative 0.0125 0.0222 0.0376
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Plasmodium vivax vivapain-1 0.1306 0.2771 0.5334
Echinococcus multilocularis Glycosyl transferase, family 35 0.0105 0.0181 0.0181
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Toxoplasma gondii proteasome subunit beta type 2, putative 0.004 0.0039 0.0059
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.17 0.3622 0.3933
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0698 0.1461 0.1447
Plasmodium vivax unspecified product 0.0542 0.1123 0.2152
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0264 0.0524 0.0905
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Brugia malayi Trypsin-like protease protein 5 0.0037 0.0033 0.0035
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.026
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0019 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Schistosoma mansoni hypothetical protein 0.0037 0.0033 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0836 0.1757 0.3073
Echinococcus granulosus tar DNA binding protein 0.0065 0.0094 0.0094
Echinococcus multilocularis Transglutaminase 0.0251 0.0496 0.0496
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.122 0.2585 0.4979
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0116 0.0204 0.0387
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0189 0.0173
Echinococcus multilocularis thyroid hormone receptor alpha 0.0158 0.0294 0.0294
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0116 0.0204 0.0204
Leishmania major centrin, putative 0.0116 0.0204 0.0343
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Echinococcus multilocularis calpain 7 (C02 family) 0.0944 0.1991 0.1991
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0118 0.0208 0.0221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1306 0.2771 0.4854
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0019 0.0021
Leishmania major hypothetical protein, conserved 0.0036 0.0032 0.0041
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0776 0.1629 0.1766
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0218 0.0218
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0039 0.0039
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0204 0.0393
Echinococcus granulosus tumor protein p63 0.0344 0.0696 0.0696
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0032 0.0016
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Schistosoma mansoni calpain (C02 family) 0.0944 0.1991 0.216
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Schistosoma mansoni histone deacetylase hda2 0.0105 0.018 0.0191
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0032 0.0062
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trichomonas vaginalis calcineurin B subunit, putative 0.0118 0.0208 0.0402
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Onchocerca volvulus 0.0045 0.005 0.0087
Echinococcus multilocularis cysteine protease 0.2426 0.5188 0.5188
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0208 0.0403 0.0694
Trypanosoma brucei prolyl oligopeptidase, putative 0.0698 0.1461 0.2552
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0039 0.0076
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Onchocerca volvulus Matrix metalloproteinase homolog 0.0053 0.0067 0.012
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.5294
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0143 0.0156
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0542 0.1123 0.2152
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1416 0.301 0.2999
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0023 0.0027
Giardia lamblia Alanyl dipeptidyl peptidase 0.0235 0.0461 0.1218
Trypanosoma brucei histone deacetylase 1 0.0088 0.0143 0.0237
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0039 0.0039
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Leishmania major hypothetical protein, conserved 0.0118 0.0208 0.0351
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0039 0.0039
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0019 0.0019
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0052 0.0036
Leishmania major hypothetical protein, conserved 0.0116 0.0204 0.0343
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0216 0.04
Onchocerca volvulus 0.0116 0.0204 0.0384
Onchocerca volvulus 0.0037 0.0033 0.0054
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0023 0.0025
Entamoeba histolytica calmodulin, putative 0.0116 0.0204 0.0387
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0542 0.1123 0.1221
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Schistosoma mansoni hypothetical protein 0.0251 0.0496 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0019 0.0021
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0028 0.0022
Schistosoma mansoni Mername-AA248 (C02 family) 0.0944 0.1991 0.216
Trypanosoma cruzi cysteine peptidase, putative 0.0764 0.1601 0.1733
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0043 0.0047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0764 0.1601 0.174
Toxoplasma gondii histone deacetylase HDAC1 0.0099 0.0167 0.0306
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Loa Loa (eye worm) calpain 5 0.0555 0.1152 0.1252
Echinococcus multilocularis Dipeptidyl peptidase 9 0.057 0.1183 0.1183
Leishmania major small myristoylated protein-1 0.036 0.073 0.1267
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0023 0.0025
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0039 0.0039
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0189 0.0173
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0019 0.0019
Trypanosoma brucei I/6 autoantigen 0.0116 0.0204 0.0343
Schistosoma mansoni mitochondrial solute carrier 0.0116 0.0204 0.0217
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Giardia lamblia Encystation-specific protease 0.0542 0.1123 0.3058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0294 0.0315
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.4655 1 1
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Plasmodium vivax centrin-1, putative 0.0116 0.0204 0.0377
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.2144
Onchocerca volvulus 0.0972 0.2052 0.395
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0116 0.0204 0.0204
Trypanosoma brucei protein I/6 0.0116 0.0204 0.0343
Leishmania major small myristoylated protein-2 0.0655 0.1368 0.2389
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0039 0.0075
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0039 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0019 0.0021
Entamoeba histolytica hypothetical protein, conserved 0.0118 0.0208 0.0396
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0542 0.1123 0.2152
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0116 0.0204 0.0387
Echinococcus multilocularis Mastin 0.0037 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0019 0.0021
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0051 0.0055
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0143 0.0156
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0043 0.0043
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.043
Trichomonas vaginalis centrin, putative 0.0116 0.0204 0.0393
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0024 0.0017
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0143 0.0143
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Trichomonas vaginalis calmodulin-2, putative 0.0116 0.0204 0.0393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1662 0.354 0.6824
Onchocerca volvulus 0.0029 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.1651 0.3518 0.3823
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0019 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.0461 0.0492
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0039 0.0076
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0189 0.0173
Loa Loa (eye worm) calpain family protein 1 0.1608 0.3425 0.3722
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Mycobacterium leprae Conserved hypothetical protein 0.0251 0.0496 0.173
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0189 0.0173
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0092 0.01
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0019 0.0021
Schistosoma mansoni cathepsin F (C01 family) 0.2426 0.5188 0.5636
Echinococcus granulosus calumenin 0.0118 0.0208 0.0208
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Mycobacterium tuberculosis Probable reductase 0.0109 0.0189 0.0173
Echinococcus granulosus pyruvate kinase 0.0033 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2426 0.5188 1
Giardia lamblia Hypothetical protein 0.0251 0.0496 0.1314
Onchocerca volvulus 0.0122 0.0218 0.0411
Onchocerca volvulus 0.0029 0.0016 0.0021
Onchocerca volvulus Prolyl endopeptidase homolog 0.1651 0.3518 0.6777
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0143 0.0156
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0118 0.0208 0.0217
Trypanosoma brucei Calpain-like protein CALP1.3 0.0597 0.1243 0.2168
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Leishmania major hypothetical protein, conserved 0.0606 0.1262 0.2202
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Toxoplasma gondii preprocathepsin c precursor, putative 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0114 0.0114
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0944 0.1991 0.2157
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0019 0.0016
Echinococcus granulosus histone deacetylase 3 0.0088 0.0143 0.0143
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0023 0.0023
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0116 0.0204 0.0377
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0051 0.0046
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Brugia malayi cathepsin B-like cysteine proteinase 0.4285 0.9202 1
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0039 0.0039
Brugia malayi Histone deacetylase family protein 0.0099 0.0167 0.0181
Onchocerca volvulus 0.0154 0.0286 0.0542
Trypanosoma brucei calpain, putative 0.0653 0.1363 0.238
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0043 0.0038
Trypanosoma brucei proteasome subunit beta type-2, putative 0.004 0.0039 0.0054
Plasmodium vivax serine-repeat antigen (SERA) 0.0542 0.1123 0.2152
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0019 0.0016
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0045 0.0049
Brugia malayi intermediate filament protein 0.0027 0.0012 0.0013
Echinococcus granulosus centrin 2 0.0116 0.0204 0.0204
Onchocerca volvulus 0.2426 0.5188 1
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0052 0.0051
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.2063
Entamoeba histolytica grainin, putative 0.0118 0.0208 0.0396
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1306 0.2771 0.5341
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0222 0.0233
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0125 0.0222 0.0222
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0045 0.0044
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0051 0.0055
Brugia malayi Peptidase C13 family protein 0.0149 0.0276 0.03
Trypanosoma brucei histone deacetylase, putative 0.0099 0.0167 0.0278
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Toxoplasma gondii EF hand domain-containing protein 0.0116 0.0204 0.0377
Plasmodium falciparum proteasome subunit beta type-5 0.0083 0.0132 0.0238
Echinococcus granulosus proteasome prosome macropain 0.0083 0.0132 0.0132
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0037 0.0033 0.0033
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.0037 0.0033 0.0054
Brugia malayi Cathepsin L-like precursor 0.1662 0.354 0.3847
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0611 0.1059
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.004 0.0039 0.007
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Leishmania major centrin, putative,caltractin, putative 0.0116 0.0204 0.0343
Brugia malayi calpain 7 0.0944 0.1991 0.2164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0019 0.0021
Onchocerca volvulus 0.0061 0.0085 0.0154
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0542 0.1123 0.2152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0724 0.1517 0.265
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0024 0.0026
Schistosoma mansoni cathepsin F (C01 family) 0.1662 0.354 0.3844
Echinococcus multilocularis tumor protein p63 0.0344 0.0696 0.0696
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Brugia malayi programmed cell death protein 6 0.0116 0.0204 0.0221
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1314 0.2789 0.2778
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) EF hand family protein 0.0116 0.0204 0.0221
Brugia malayi beta-lactamase 0.0036 0.0032 0.0035
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0898 0.1892 0.1892
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Echinococcus granulosus neurocalcin 0.0116 0.0204 0.0204
Schistosoma mansoni cathepsin C 0.0542 0.1123 0.1216
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Mycobacterium ulcerans hypothetical protein 0.0037 0.0033 0.0017
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2164 0.4623 0.5022
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.2168
Loa Loa (eye worm) hypothetical protein 0.0321 0.0646 0.0702
Brugia malayi Blistered cuticle protein 3 0.0064 0.0092 0.01
Schistosoma mansoni hypothetical protein 0.0509 0.1053 0.1139
Echinococcus granulosus lamin dm0 0.0027 0.0012 0.0012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Toxoplasma gondii ABC1 family protein 0.0036 0.0032 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0019 0.0019
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0653 0.1363 0.238
Trypanosoma cruzi prolyl endopeptidase 0.1651 0.3518 0.3817
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0542 0.1123 0.2161
Trypanosoma brucei Calpain-like protein 1.1 0.0939 0.198 0.3464
Giardia lamblia Proteasome subunit beta type 2 0.004 0.0039 0.0046
Brugia malayi Kringle domain containing protein 0.0045 0.005 0.0054
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0542 0.1123 0.1216
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0019 0.0019
Plasmodium falciparum serine repeat antigen 3 0.0542 0.1123 0.2152
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.13
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trypanosoma brucei histone deacetylase 3 0.0099 0.0167 0.0278
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Toxoplasma gondii proteasome subunit beta type, putative 0.0083 0.0132 0.0238
Echinococcus granulosus tachykinin peptides receptor 99D 0.0898 0.1892 0.1892
Brugia malayi cathepsin L precursor 0.0542 0.1123 0.1221
Onchocerca volvulus 0.0064 0.0092 0.0169
Trypanosoma cruzi cruzipain precursor, putative 0.0764 0.1601 0.1733
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Entamoeba histolytica protein kinase, putative 0.0555 0.1152 0.2216
Brugia malayi prolyl oligopeptidase family protein 0.1651 0.3518 0.3823
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0023 0.0023
Onchocerca volvulus Cathepsin L homolog 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0143 0.0261
Onchocerca volvulus 0.0031 0.0019 0.0029
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1209 0.2562 0.4486
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0257 0.0279
Loa Loa (eye worm) RNA binding protein 0.0065 0.0094 0.0103
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0028 0.0035
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0023 0.0015
Schistosoma mansoni hypothetical protein 0.0132 0.0239 0.0255
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.043
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0542 0.1123 0.2152
Mycobacterium leprae Conserved hypothetical protein 0.0251 0.0496 0.173
Trichomonas vaginalis hypothetical protein 0.0389 0.0793 0.1528
Schistosoma mansoni hypothetical protein 0.0099 0.0167 0.0177
Onchocerca volvulus 0.2426 0.5188 1
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0208 0.0386
Echinococcus multilocularis microtubule associated protein 2 0.2086 0.4456 0.4456
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trypanosoma brucei centrin, putative 0.0116 0.0204 0.0343
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Loa Loa (eye worm) hypothetical protein 0.1608 0.3425 0.3722
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0116 0.0204 0.0343
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0235 0.0461 0.0873
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Onchocerca volvulus 0.0027 0.0012 0.0015
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0032 0.0035
Schistosoma mansoni cathepsin s 0.0764 0.1601 0.1736
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Brugia malayi PXA domain containing protein 0.004 0.0039 0.0042
Entamoeba histolytica grainin 2 0.0124 0.0221 0.0421
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0039 0.0042
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0032 0.0032
Loa Loa (eye worm) cysteine protease 0.2426 0.5188 0.5639
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0125 0.0222 0.0222
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0204 0.0343
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Schistosoma mansoni calmodulin 0.0116 0.0204 0.0217
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0039 0.0042
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0496 0.0481
Echinococcus granulosus expressed protein 0.0769 0.1614 0.1614
Brugia malayi nuclear hormone receptor 0.0031 0.0019 0.0021
Loa Loa (eye worm) prolyl oligopeptidase 0.0811 0.1705 0.1853
Trypanosoma cruzi centrin-3 0.0124 0.0221 0.0232
Schistosoma mansoni hypothetical protein 0.0115 0.0201 0.0214
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0212
Echinococcus multilocularis enteropeptidase 0.0037 0.0033 0.0033
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0019 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Toxoplasma gondii subtilisin SUB12 0.0029 0.0016 0.0014
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Trypanosoma brucei oligopeptidase b 0.0698 0.1461 0.2552
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0051 0.0075
Echinococcus granulosus calpain A 0.0944 0.1991 0.1991
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0064 0.0092 0.0092
Trypanosoma brucei calpain, putative 0.0389 0.0793 0.1378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0181 0.0181
Trypanosoma brucei Component of motile flagella 41 0.0116 0.0204 0.0343
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0698 0.1461 0.2552
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Loa Loa (eye worm) trypsin family protein 0.0037 0.0033 0.0035
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Toxoplasma gondii hypothetical protein 0.0389 0.0793 0.1514
Brugia malayi Cell death protein 3 precursor 0.0061 0.0085 0.0092
Onchocerca volvulus Cathepsin L homolog 0.2426 0.5188 1
Trypanosoma cruzi 20S proteasome subunit 0.004 0.0039 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0216 0.023
Brugia malayi hypothetical protein 0.0061 0.0085 0.0092
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Schistosoma mansoni centrin-related 0.0116 0.0204 0.0217
Brugia malayi cathepsin F-like cysteine proteinase 0.0542 0.1123 0.1221
Echinococcus granulosus survival motor neuron protein 1 0.0486 0.1003 0.1003
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0028 0.0028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.1486 0.1607
Trichomonas vaginalis myosin light chain 1, putative 0.0116 0.0204 0.0393
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma brucei Calpain-like protein 2 0.0724 0.1517 0.265
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.2718
Onchocerca volvulus 0.0029 0.0016 0.0021
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0039 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0257 0.0257
Brugia malayi Cytochrome P450 family protein 0.0045 0.0051 0.0055
Trypanosoma cruzi I/6 autoantigen, putative 0.0116 0.0204 0.0212
Echinococcus granulosus calpain 7 C02 family 0.0944 0.1991 0.1991
Schistosoma mansoni reticulocalbin 0.0116 0.0204 0.0217
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Plasmodium falciparum peptidase, putative 0.0235 0.0461 0.0873
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0019 0.0016
Brugia malayi prolyl oligopeptidase family protein 0.0235 0.0461 0.0501
Trypanosoma brucei calmodulin, putative 0.0118 0.0208 0.0351
Echinococcus multilocularis acylamino acid releasing enzyme 0.0235 0.0461 0.0461
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Brugia malayi Thioredoxin family protein 0.0251 0.0496 0.0539
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0167 0.0176
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Trypanosoma brucei small myristoylated protein 1-1 0.036 0.073 0.1267
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0542 0.1123 0.2165
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Echinococcus granulosus cathepsin L 0.1306 0.2771 0.2771
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0052 0.0094
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0542 0.1123 0.2161
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0343
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0338 0.0682 0.1184
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Leishmania major programmed cell death 6 protein-like protein 0.0116 0.0204 0.0343
Loa Loa (eye worm) hypothetical protein 0.0122 0.0218 0.0237
Trypanosoma brucei calmodulin, putative 0.0116 0.0204 0.0343
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Trypanosoma brucei kinesin, putative 0.0555 0.1152 0.2009
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0023 0.0023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0854 0.1797 0.1952
Mycobacterium ulcerans proteasome PrcB 0.0083 0.0132 0.0116
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0022 0.0026
Schistosoma mansoni microtubule-associated protein tau 0.2086 0.4456 0.484
Echinococcus multilocularis peroxidasin 0.0064 0.0092 0.0092
Onchocerca volvulus 0.0042 0.0043 0.0075
Brugia malayi Matrixin family protein 0.0057 0.0077 0.0084
Trypanosoma brucei prolyl endopeptidase 0.1651 0.3518 0.6166
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0561
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Plasmodium vivax proteasome subunit beta type-5, putative 0.0083 0.0132 0.0238
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0181 0.0349
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0032 0.0016
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0216 0.023
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0143 0.0143
Echinococcus granulosus EF hand domain containing family member A2 0.0118 0.0208 0.0208
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0208 0.0403 0.0694
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0235 0.0461 0.0873
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0064 0.0092 0.0092
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0028 0.0038
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1135 0.2402 0.2604
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.0456 0.0441
Trichomonas vaginalis esterase, putative 0.0036 0.0032 0.0062
Brugia malayi hypothetical protein 0.0154 0.0286 0.031
Echinococcus granulosus microtubule associated protein 2 0.2086 0.4456 0.4456
Entamoeba histolytica cysteine proteinase 2 0.1306 0.2771 0.5339
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0019 0.0021
Brugia malayi steroid hormone receptor 0.0031 0.0019 0.0021
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.4874
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0051 0.0046
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0542 0.1123 0.2152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0083 0.0132 0.0116
Echinococcus multilocularis chromatin regulatory protein sir2 0.0125 0.0222 0.0222
Echinococcus multilocularis calpain 5 0.0944 0.1991 0.1991
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0083 0.0132 0.0418
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.2063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi prolyl oligopeptidase family protein 0.0235 0.0461 0.0501
Echinococcus granulosus histone deacetylase 6 0.0099 0.0167 0.0167
Plasmodium vivax proteasome subunit beta type-1, putative 0.0064 0.0092 0.0161
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Onchocerca volvulus 0.0037 0.0033 0.0054
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1209 0.2562 0.2777
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Toxoplasma gondii hypothetical protein 0.0029 0.0016 0.0014
Leishmania major small myristoylated protein 4, putative 0.0567 0.1177 0.2053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi Histone deacetylase 1 0.0088 0.0143 0.0156
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.228 0.4874 0.4874
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.0033
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0116 0.0204 0.0212
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0698 0.1461 0.1447
Onchocerca volvulus 0.2426 0.5188 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Brugia malayi calpain family protein 1 0.2164 0.4623 0.5024
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Giardia lamblia Alanyl dipeptidyl peptidase 0.0235 0.0461 0.1218
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Echinococcus granulosus enteropeptidase 0.0037 0.0033 0.0033
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0239 0.026
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0215 0.02
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Toxoplasma gondii calcium-dependent protein kinase 0.0118 0.0208 0.0386
Echinococcus multilocularis calpain A 0.2282 0.4878 0.4878
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Trypanosoma cruzi I/6 autoantigen, putative 0.0116 0.0204 0.0212
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0056 0.0075 0.0082
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1651 0.3518 0.382
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) calpain 0.0944 0.1991 0.2164
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Leishmania major centrin, putative 0.0116 0.0204 0.0343
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0028 0.0028
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0542 0.1123 0.2152
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0459 0.0945 0.1808
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Schistosoma mansoni calpain-7 (C02 family) 0.0947 0.1998 0.2167
Schistosoma mansoni reticulocalbin 0.0118 0.0208 0.0221
Toxoplasma gondii cathepsin CPC1 0.0542 0.1123 0.2152
Brugia malayi TAR-binding protein 0.0065 0.0094 0.0103
Plasmodium falciparum serine repeat antigen 6 0.0542 0.1123 0.2152
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0092
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.1486 0.2595
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0235 0.0461 0.0496
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0039 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0045 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0032 0.0026
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Leishmania major proteasome beta 5 subunit, putative 0.0083 0.0132 0.0216
Echinococcus granulosus peroxidasin 0.0064 0.0092 0.0092
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0039 0.0037
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0064 0.0092 0.0147
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0043 0.0084
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Schistosoma mansoni centrin 0.0116 0.0204 0.0217
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0016 0.0014
Onchocerca volvulus 0.2426 0.5188 1
Loa Loa (eye worm) matrixin family protein 0.0057 0.0077 0.0084
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Loa Loa (eye worm) hypothetical protein 0.0486 0.1003 0.109
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0149 0.0276 0.0295
Echinococcus granulosus histone deacetylase 6 0.0105 0.018 0.018
Leishmania major META domain containing protein 0.0208 0.0403 0.0694
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0024 0.0047
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0698 0.1461 0.158
Schistosoma mansoni coup transcription factor 0.0031 0.0019 0.0016
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1306 0.2771 0.3005
Onchocerca volvulus 0.0029 0.0016 0.0021
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0046 0.0072
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Plasmodium falciparum histone deacetylase 2 0.0099 0.0167 0.0306
Brugia malayi Protein kinase domain containing protein 0.0045 0.005 0.0054
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Plasmodium falciparum serine repeat antigen 5 0.0542 0.1123 0.2152
Trypanosoma cruzi major cysteine proteinase, putative 0.0542 0.1123 0.1213
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni hypothetical protein 0.0509 0.1053 0.1139
Brugia malayi hypothetical protein 0.0026 0.0008 0.0009
Entamoeba histolytica calcium binding family protein 0.0116 0.0204 0.0387
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0039 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0939 0.198 0.2144
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Leishmania major kinesin, putative 0.0555 0.1152 0.2009
Loa Loa (eye worm) hypothetical protein 0.0116 0.0204 0.0221
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0051 0.0055
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0764 0.1601 0.174
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0024 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0043 0.0047
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0222 0.0429
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0019 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Onchocerca volvulus 0.0116 0.0204 0.0384
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Onchocerca volvulus 0.2426 0.5188 1
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0811 0.1705 0.1705
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0167 0.0167
Onchocerca volvulus 0.0029 0.0016 0.0021
Mycobacterium leprae Probable lipase LipE 0.0036 0.0032 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Echinococcus granulosus intermediate filament protein 0.0027 0.0012 0.0012
Leishmania major calpain family cysteine protease-like protein 0.0597 0.1243 0.2168
Toxoplasma gondii hypothetical protein 0.0029 0.0016 0.0014
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0542 0.1123 0.2152
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.1683
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0389 0.0793 0.1528
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0019 0.0016
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Plasmodium falciparum thioredoxin reductase 0.0048 0.0057 0.0093
Echinococcus granulosus prolyl endopeptidase 0.1651 0.3518 0.3518
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0019 0.0016
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0032 0.0016
Trypanosoma cruzi cruzipain precursor, putative 0.2663 0.57 0.6191
Onchocerca volvulus 0.0064 0.0092 0.0169
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0051 0.0074
Echinococcus multilocularis calbindin 32 0.0118 0.0208 0.0208
Brugia malayi Hemopexin family protein 0.0034 0.0026 0.0028
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0032 0.0016
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Schistosoma mansoni peroxidasin 0.0064 0.0092 0.0095
Echinococcus granulosus caspase 2 0.0061 0.0085 0.0085
Brugia malayi hypothetical protein 0.0123 0.0219 0.0238
Schistosoma mansoni histone deacetylase 0.0088 0.0143 0.0151
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0039 0.0042
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0218 0.0218
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Leishmania major calcineurin B subunit, putative 0.0116 0.0204 0.0343
Echinococcus granulosus inhibitor of apoptosis protein 0.0132 0.0239 0.0239
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Mycobacterium ulcerans beta-lactamase 0.0036 0.0032 0.0016
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.005 0.005
Leishmania major hypothetical protein, unknown function 0.0389 0.0793 0.1378
Echinococcus multilocularis cathepsin b 0.4285 0.9202 0.9202
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0057 0.0052
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0013
Echinococcus multilocularis calcium uptake protein 1 0.0118 0.0208 0.0208
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Schistosoma mansoni hypothetical protein 0.0061 0.0085 0.0087
Onchocerca volvulus 0.0542 0.1123 0.2158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0023 0.0007
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0024 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1306 0.2771 0.5341
Echinococcus granulosus Glycosyl transferase family 35 0.0105 0.0181 0.0181
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0143 0.0261
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0181 0.0181
Entamoeba histolytica hypothetical protein 0.0542 0.1123 0.2161
Brugia malayi GPI-anchor transamidase 0.0035 0.0028 0.0031
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0039 0.0039
Giardia lamblia Cathepsin L-like protease 0.0542 0.1123 0.3058
Echinococcus multilocularis cathepsin L cysteine protease 0.2426 0.5188 0.5188
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0083 0.0132 0.0254
Toxoplasma gondii cathepsin CPC2 0.0542 0.1123 0.2152
Brugia malayi cathepsin F-like cysteine proteinase 0.0764 0.1601 0.174
Echinococcus granulosus calpain A 0.2282 0.4878 0.4878
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0216 0.0216
Loa Loa (eye worm) sirtuin 4 0.0032 0.0023 0.0025
Giardia lamblia Serine peptidase, putative 0.0042 0.0043 0.0058
Plasmodium vivax serine-repeat antigen (SERA) 0.0542 0.1123 0.2152
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.005 0.0054
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0811 0.1705 0.328
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0222 0.0429
Trypanosoma cruzi oligopeptidase b 0.0698 0.1461 0.158
Echinococcus multilocularis calumenin 0.0118 0.0208 0.0208
Toxoplasma gondii cathepsin B 0.17 0.3622 0.6975
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Brugia malayi Peroxidasin 0.0064 0.0092 0.01
Onchocerca volvulus 0.0064 0.0092 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.0516
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0389 0.0793 0.1378
Echinococcus multilocularis musashi 0.0027 0.0012 0.0012
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Entamoeba histolytica hypothetical protein, conserved 0.0235 0.0461 0.0883
Echinococcus granulosus lamin 0.0027 0.0012 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1209 0.2562 0.2777
Mycobacterium tuberculosis Long conserved protein 0.0251 0.0496 0.0481
Brugia malayi cathepsin Z-like cysteine proteinase 0.0542 0.1123 0.1221
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0143 0.0271
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0811 0.1705 0.1705
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.2157
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0019 0.0029
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0045 0.0071
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0064 0.0092 0.0095
Echinococcus granulosus dna polymerase eta 0.0045 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Brugia malayi PXA domain containing protein 0.004 0.0039 0.0042
Schistosoma mansoni ef hand domain family member A2 0.0116 0.0204 0.0217
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4285 0.9202 1
Echinococcus granulosus histone deacetylase 8 0.0042 0.0045 0.0045
Trypanosoma cruzi centrin, putative 0.0124 0.0221 0.0232
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0032 0.0046
Loa Loa (eye worm) hypothetical protein 0.0035 0.0028 0.0031
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0023 0.0027
Giardia lamblia Proteasome subunit beta type 1 0.0064 0.0092 0.0193
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0257 0.0257
Plasmodium falciparum cysteine proteinase falcipain 2b 0.2426 0.5188 1
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.005 0.005
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.3484
Onchocerca volvulus Glycogen phosphorylase homolog 0.0105 0.0181 0.034
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0167 0.0176
Schistosoma mansoni hypothetical protein 0.0034 0.0026 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0062 0.0063
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1314 0.2789 1
Mycobacterium ulcerans lipase LipD 0.0036 0.0032 0.0016
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0542 0.1123 0.2152
Onchocerca volvulus 0.0036 0.0032 0.0053
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0083 0.0132 0.0143
Onchocerca volvulus Peroxidase homolog 0.0064 0.0092 0.0169
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0023 0.0025
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0043 0.0058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Echinococcus granulosus pyruvate kinase 0.0033 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0542 0.1123 0.2165
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Plasmodium falciparum histone deacetylase 1 0.0088 0.0143 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0019 0.0021
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0138 0.0251 0.0251
Schistosoma mansoni histone deacetylase 0.0088 0.0143 0.0151
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Brugia malayi beta-lactamase family protein 0.0036 0.0032 0.0035
Onchocerca volvulus 0.0029 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0092 0.0169
Plasmodium vivax glutathione reductase, putative 0.0048 0.0057 0.0093
Echinococcus multilocularis histone deacetylase 7 0.0099 0.0167 0.0167
Echinococcus multilocularis glycoprotein Antigen 5 0.0037 0.0033 0.0033
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0039 0.0037
Toxoplasma gondii kringle domain-containing protein 0.0045 0.005 0.0079
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0003 0.0003
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0023 0.0015
Brugia malayi Pre-SET motif family protein 0.0122 0.0218 0.0237
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0039 0.0039
Trichomonas vaginalis calmodulin, putative 0.0124 0.0221 0.0427
Echinococcus multilocularis transmembrane protease serine 3 0.0037 0.0033 0.0033
Onchocerca volvulus 0.2426 0.5188 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0023 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.005 0.0079
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.004 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0276 0.0295
Plasmodium vivax proteasome subunit beta type-2, putative 0.004 0.0039 0.0059
Giardia lamblia Cathepsin L-like protease 0.0542 0.1123 0.3058
Trypanosoma brucei small myristoylated protein 1-2 0.036 0.073 0.1267
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0776 0.1629 0.1629
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0542 0.1123 0.1216
Schistosoma mansoni cathepsin B (C01 family) 0.0542 0.1123 0.1216
Mycobacterium ulcerans hypothetical protein 0.0251 0.0496 0.0481
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0032 0.0035
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0039 0.0039
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Trypanosoma cruzi small myristoylated protein 1-2 0.036 0.073 0.0784
Schistosoma mansoni survival motor neuron protein 0.0099 0.0167 0.0177
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0052 0.0036
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0776 0.1629 0.1629
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0043 0.0084
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.057 0.1183 0.1277
Brugia malayi Pre-SET motif family protein 0.0854 0.1797 0.1952
Entamoeba histolytica calpain large subunit domain III containing protein 0.0555 0.1152 0.2216
Echinococcus multilocularis cathepsin L 0.1306 0.2771 0.2771
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Brugia malayi prolyl oligopeptidase family protein 0.0811 0.1705 0.1853
Brugia malayi cathepsin Z-like cysteine proteinase 0.0542 0.1123 0.1221
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Echinococcus multilocularis expressed protein 0.0769 0.1614 0.1614
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0086 0.014 0.014
Onchocerca volvulus 0.0118 0.0208 0.0393
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1209 0.2562 0.2777
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0189 0.0173
Loa Loa (eye worm) hypothetical protein 0.0063 0.0089 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0019 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Trypanosoma brucei centrin-3 0.0124 0.0221 0.0374
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0836 0.1757 0.3073
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0181 0.0181
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0022 0.0015
Echinococcus granulosus calpain 0.0944 0.1991 0.1991
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Mycobacterium ulcerans thymidine phosphorylase 0.4655 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0338 0.0682 0.1315
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0057 0.0041
Echinococcus granulosus calcium uptake protein 1 0.0118 0.0208 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Echinococcus granulosus cathepsin l1 0.1662 0.354 0.354
Plasmodium vivax unspecified product 0.1306 0.2771 0.5334
Echinococcus granulosus chromatin regulatory protein sir2 0.0125 0.0222 0.0222
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Leishmania major histone deacetylase, putative 0.0099 0.0167 0.0278
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.005 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Echinococcus granulosus Transglutaminase 0.0251 0.0496 0.0496
Trypanosoma cruzi kinesin, putative 0.0555 0.1152 0.1244
Plasmodium falciparum serine repeat antigen 1 0.0542 0.1123 0.2152
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0181 0.0343
Loa Loa (eye worm) prolyl oligopeptidase 0.0235 0.0461 0.0501
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0094 0.0094
Leishmania major calmodulin-like protein 0.0116 0.0204 0.0343
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Echinococcus multilocularis neurocalcin 0.0116 0.0204 0.0204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Brugia malayi carbohydrate phosphorylase 0.0105 0.0181 0.0197
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Echinococcus granulosus proteasome prosome macropain subunit beta 0.004 0.0039 0.0039
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0039 0.0039
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0235 0.0461 0.0888
Giardia lamblia Histone deacetylase 0.0088 0.0143 0.0336
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0064 0.0092 0.0177
Onchocerca volvulus 0.0029 0.0016 0.0021
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0389 0.0793 0.1378
Plasmodium falciparum cysteine proteinase falcipain 1 0.1306 0.2771 0.5334
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0092 0.0169
Trypanosoma brucei hypothetical protein 0.0653 0.1363 0.238
Plasmodium falciparum glutathione reductase 0.0048 0.0057 0.0093
Loa Loa (eye worm) calmodulin-like protein 0.0116 0.0204 0.0221
Loa Loa (eye worm) matrixin family protein 0.0053 0.0067 0.0073
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0086 0.014 0.014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0208 0.0208
Brugia malayi calcium-binding protein 0.0116 0.0204 0.0221
Loa Loa (eye worm) hypothetical protein 0.0045 0.0051 0.0056
Leishmania major DNA polymerase eta, putative 0.0045 0.0051 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0181 0.0343
Plasmodium falciparum serine repeat antigen 8 0.0542 0.1123 0.2152
Schistosoma mansoni pyruvate kinase 0.0033 0.0024 0.0021
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0094 0.0103
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0039 0.0039
Onchocerca volvulus 0.1662 0.354 0.6821
Echinococcus granulosus Mastin 0.0037 0.0033 0.0033
Onchocerca volvulus 0.0029 0.0016 0.0021
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0235 0.0461 0.0883
Onchocerca volvulus 0.005 0.0062 0.0111
Schistosoma mansoni calmodulin related calcium binding protein 0.0116 0.0204 0.0217
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Schistosoma mansoni hypothetical protein 0.0116 0.0204 0.0217
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0597 0.1243 0.1342
Trypanosoma brucei antigen, putative 0.0944 0.1991 0.3484
Echinococcus granulosus geminin 0.0509 0.1053 0.1053
Brugia malayi histone deacetylase 11 0.0042 0.0045 0.0049
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Leishmania major oligopeptidase b 0.0698 0.1461 0.2552
Echinococcus granulosus calpain 5 0.0944 0.1991 0.1991
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0698 0.1461 0.158
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0084
Onchocerca volvulus 0.0037 0.0033 0.0054
Leishmania major cytochrome p450-like protein 0.0045 0.0051 0.0074
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0032 0.0026
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0698 0.1461 0.2552
Giardia lamblia Glycogen phosphorylase 0.0105 0.0181 0.044
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0039 0.0039
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1651 0.3518 0.382
Schistosoma mansoni inhibitor of apoptosis protein 0.0132 0.0239 0.0255
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi ecdysteroid receptor 0.0031 0.0019 0.0021
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0019 0.0019
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.1277
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0005 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.2426 0.5188 0.5634
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0257 0.0279
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0085 0.0154
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0009
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Brugia malayi hypothetical protein 0.0224 0.0438 0.0475
Brugia malayi proteasome subunit beta type 2 0.004 0.0039 0.0043
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0016 0.0014
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trypanosoma cruzi major cysteine proteinase, putative 0.0779 0.1634 0.1769
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0012 0.0013
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0023 0.0023
Echinococcus multilocularis inhibitor of apoptosis protein 0.0132 0.0239 0.0239
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Onchocerca volvulus 0.0037 0.0033 0.0054
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0944 0.1991 0.2157
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0116 0.0204 0.0212
Echinococcus multilocularis calmodulin 0.0116 0.0204 0.0204
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0542 0.1123 0.1216
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0019 0.0016
Loa Loa (eye worm) beta-lactamase 0.0036 0.0032 0.0035
Echinococcus multilocularis EF hand domain containing family member A2 0.0116 0.0204 0.0204
Schistosoma mansoni calpain-7 (C02 family) 0.0947 0.1998 0.2167
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.1486 0.1607
Onchocerca volvulus 0.0034 0.0026 0.0041
Echinococcus granulosus cysteine protease 0.1306 0.2771 0.2771
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Schistosoma mansoni hypothetical protein 0.0052 0.0066 0.0067
Entamoeba histolytica calmodulin, putative 0.0116 0.0204 0.0387
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0499 0.0543
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0542 0.1123 0.2152
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0215 0.02
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0092 0.0091
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0045 0.004
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0023 0.0027
Trypanosoma brucei mitochondrial calcium uptake 1 0.0116 0.0204 0.0343
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0023 0.0038
Echinococcus granulosus cathepsin L 0.0542 0.1123 0.1123
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Echinococcus multilocularis cathepsin L 0.0542 0.1123 0.1123
Loa Loa (eye worm) cathepsin B 0.17 0.3622 0.3936
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Chlamydia trachomatis glycogen phosphorylase 0.0105 0.0181 1
Leishmania major DNA polymerase eta, putative 0.0032 0.0022 0.0024
Leishmania major histone deacetylase, putative 0.0099 0.0167 0.0278
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Leishmania major histone deacetylase, putative 0.0088 0.0143 0.0237
Loa Loa (eye worm) hypothetical protein 0.122 0.2585 0.281
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.17 0.3622 0.6349
Schistosoma mansoni memapsin-2 (A01 family) 0.0429 0.0879 0.095
Trichomonas vaginalis conserved hypothetical protein 0.0542 0.1123 0.2165
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Plasmodium vivax unspecified product 0.0764 0.1601 0.3075
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0064 0.0092 0.0172
Trichomonas vaginalis peptide N-glycanase, putative 0.0251 0.0496 0.0955
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0019 0.0019
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Brugia malayi calpain family protein 1 0.2164 0.4623 0.5024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Schistosoma mansoni hypothetical protein 0.0389 0.0793 0.0857
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0023 0.0038
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0092 0.0091
Mycobacterium ulcerans transglutaminase family protein 0.0251 0.0496 0.0481
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0132 0.0134
Loa Loa (eye worm) hypothetical protein 0.0138 0.0251 0.0273
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.2426 0.5188 0.5639
Schistosoma mansoni cathepsin S (C01 family) 0.0542 0.1123 0.1216
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.13
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0222 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Loa Loa (eye worm) glutathione reductase 0.0048 0.0057 0.0062
Plasmodium falciparum serine repeat antigen 2 0.0542 0.1123 0.2152
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0032 0.0041
Onchocerca volvulus 0.0029 0.0016 0.0021
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1314 0.2789 0.2778
Brugia malayi prolyl oligopeptidase family protein 0.057 0.1183 0.1285
Leishmania major trypanothione reductase 0.0048 0.0057 0.0085
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0039 0.0039
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0019 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1306 0.2771 0.4854
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0024 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0042 0.0045 0.0049
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0024 0.0026
Trypanosoma brucei histone deacetylase 4 0.0099 0.0167 0.0278
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0257 0.0257
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0181 0.0181
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0029 0.0016 0.0017
Onchocerca volvulus 0.0029 0.0016 0.0021
Toxoplasma gondii EFHC1, putative 0.0116 0.0204 0.0377
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0228 0.0228
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trypanosoma brucei calpain-like protein, putative 0.1209 0.2562 0.4486
Leishmania major calmodulin, putative 0.0116 0.0204 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.5294
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0132 0.0239 0.0255
Onchocerca volvulus Cathepsin L homolog 0.0542 0.1123 0.2158
Loa Loa (eye worm) calpain family protein 1 0.2164 0.4623 0.5024
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0116 0.0204 0.0393
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Echinococcus multilocularis hypothetical protein 0.0944 0.1991 0.1991
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0181 0.0192
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0051 0.0046
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Loa Loa (eye worm) histone deacetylase 7A 0.0099 0.0167 0.0181
Loa Loa (eye worm) histone deacetylase 0.0099 0.0167 0.0181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Giardia lamblia Hypothetical protein 0.0542 0.1123 0.3058
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0019 0.0029
Brugia malayi hypothetical protein 0.0486 0.1003 0.109
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0132 0.0239 0.0239
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0611 0.1059
Mycobacterium ulcerans hypothetical protein 0.0036 0.0032 0.0016
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0023 0.0025
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0542 0.1123 0.2152
Leishmania major i/6 autoantigen-like protein 0.0116 0.0204 0.0343
Giardia lamblia Hypothetical protein 0.0542 0.1123 0.3058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0064 0.0092 0.0161
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0024 0.0028
Echinococcus multilocularis calpain 0.0944 0.1991 0.1991
Loa Loa (eye worm) RGS-3 protein 0.004 0.0039 0.0042
Echinococcus multilocularis lamin 0.0027 0.0012 0.0012
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Plasmodium vivax histone deacetylase 2, putative 0.0099 0.0167 0.0306
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.2168
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0043 0.0038
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0235 0.0461 0.0888
Trichomonas vaginalis calcium binding proteins, putative 0.0116 0.0204 0.0393
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0032 0.003
Plasmodium vivax vivapain-2 0.2426 0.5188 1
Loa Loa (eye worm) programmed cell death protein 6 0.0118 0.0208 0.0226
Toxoplasma gondii prolyl endopeptidase 0.1651 0.3518 0.6775
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0181 0.0192
Brugia malayi transcriptional regulator, Sir2 family protein 0.0125 0.0222 0.0242
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Brugia malayi EF hand family protein 0.0118 0.0208 0.0226
Toxoplasma gondii hypothetical protein 0.0235 0.0461 0.0873
Echinococcus multilocularis caspase 2 0.0061 0.0085 0.0085
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0019 0.0019
Entamoeba histolytica calcium-binding protein, putative 0.0116 0.0204 0.0387
Echinococcus multilocularis dna polymerase eta 0.0045 0.0051 0.0051
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0094 0.0103
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Mycobacterium ulcerans hypothetical protein 0.0251 0.0496 0.0481
Loa Loa (eye worm) proteasome subunit beta type 1 0.0064 0.0092 0.01
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1651 0.3518 0.6166
Echinococcus granulosus EF HAND 1 calcium binding site 0.0116 0.0204 0.0204
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Schistosoma mansoni calpain-2 (C02 family) 0.0389 0.0793 0.0857
Echinococcus multilocularis cathepsin b 0.4285 0.9202 0.9202
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0216 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0084
Schistosoma mansoni axis inhibition protein axin 0.004 0.0039 0.0037
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0116 0.0204 0.0217
Brugia malayi Cytochrome P450 family protein 0.0058 0.0077 0.0084
Plasmodium falciparum serine repeat antigen 9 0.0542 0.1123 0.2152
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0023 0.0007
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Brugia malayi Proteasome A-type and B-type family protein 0.0083 0.0132 0.0143
Onchocerca volvulus 0.2426 0.5188 1
Leishmania major small myristoylated protein-3, putative 0.0305 0.0611 0.1059
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0085 0.0087
Toxoplasma gondii centrin 0.0116 0.0204 0.0377
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.005 0.0045
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Echinococcus multilocularis survival motor neuron protein 1 0.0486 0.1003 0.1003
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Brugia malayi NAD-dependent deacetylase SIRT1 0.0138 0.0251 0.0273
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Schistosoma mansoni calpain C (C02 family) 0.0944 0.1991 0.216
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Echinococcus granulosus glycoprotein Antigen 5 0.0037 0.0033 0.0033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Onchocerca volvulus 0.0027 0.0012 0.0015
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0698 0.1461 0.521
Echinococcus multilocularis thymidine phosphorylase 0.4655 1 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0039 0.0038
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0032 0.0016
Trichomonas vaginalis set domain proteins, putative 0.0972 0.2051 0.3954
Echinococcus multilocularis histone deacetylase 6 0.0105 0.018 0.018
Leishmania major hypothetical protein, conserved 0.0338 0.0682 0.1184
Trypanosoma brucei cysteine peptidase C (CPC) 0.17 0.3622 0.6349
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Echinococcus multilocularis programmed cell death protein 0.0124 0.0221 0.0221
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0235 0.0461 0.0496
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Trypanosoma cruzi unspecified product 0.036 0.073 0.0784
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Giardia lamblia Transglutaminase/protease, putative 0.0251 0.0496 0.1314
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0032 0.0016
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0037 0.0033 0.0033
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0181 0.0349
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0208 0.0403 0.0694
Mycobacterium tuberculosis Probable peptidase 0.0698 0.1461 0.1447
Echinococcus granulosus acylamino acid releasing enzyme 0.0235 0.0461 0.0461
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.057 0.1183 0.1281
Onchocerca volvulus 0.0099 0.0167 0.0314
Echinococcus granulosus neuronal calcium sensor 0.0116 0.0204 0.0204
Trypanosoma cruzi conserved protein 0.0606 0.1262 0.1363
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0811 0.1705 0.1848
Toxoplasma gondii thioredoxin reductase 0.0048 0.0057 0.0093
Leishmania major cysteine peptidase A (CPA) 0.2426 0.5188 0.9102
Onchocerca volvulus 0.0251 0.0496 0.0947
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Trypanosoma brucei Calpain-like protein 1.2 0.0742 0.1555 0.2718
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0019 0.0021
Echinococcus granulosus cathepsin l1 0.2426 0.5188 0.5188
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0189 0.0625
Plasmodium vivax histone deacetylase, putative 0.0099 0.0167 0.0306
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0132 0.0239 0.0239
Echinococcus granulosus cathepsin L cysteine proteinase 0.2426 0.5188 0.5188
Onchocerca volvulus Deterin homolog 0.0132 0.0239 0.0452
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1135 0.2402 0.2604
Onchocerca volvulus 0.0132 0.0239 0.0452
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0019 0.0021
Trypanosoma brucei caltractin, putative 0.0124 0.0221 0.0374
Trypanosoma cruzi oligopeptidase b 0.0698 0.1461 0.158
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0085 0.0085
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0077 0.0084
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0023 0.0027
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0043 0.0043
Toxoplasma gondii troponin c, isotype gamma, putative 0.0116 0.0204 0.0377
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0016 0.0014
Loa Loa (eye worm) peptidase C13 family protein 0.0149 0.0276 0.03
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Trypanosoma brucei centrin, putative 0.0116 0.0204 0.0343
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0039 0.0042
Trichomonas vaginalis calmodulin, putative 0.0118 0.0208 0.0402
Brugia malayi fibroinase precursor 0.0542 0.1123 0.1221
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.2144
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0239 0.026
Plasmodium falciparum proteasome subunit beta type-2, putative 0.004 0.0039 0.0059
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0235 0.0461 0.0888
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Echinococcus granulosus transmembrane protease serine 3 0.0037 0.0033 0.0033
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0224 0.0438 0.0475
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0222 0.0423
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0866 0.1823 0.1823
Loa Loa (eye worm) papain family cysteine protease containing protein 0.2426 0.5188 0.5639
Plasmodium vivax vivapain-3 0.1306 0.2771 0.5334
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0043 0.0084
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0496 0.0481
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.4486
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0019 0.0016
Trichomonas vaginalis calcineurin B subunit, putative 0.0116 0.0204 0.0393
Trypanosoma brucei cysteine peptidase, putative 0.0597 0.1243 0.2168
Loa Loa (eye worm) hypothetical protein 0.2164 0.4623 0.5024
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.055 0.114 0.1231
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0083 0.0132 0.0248
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0019 0.0021
Trichomonas vaginalis calcium binding protein, putative 0.0124 0.0221 0.0427
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0092
Plasmodium falciparum centrin-1 0.0116 0.0204 0.0377
Toxoplasma gondii centrin, putative 0.0116 0.0204 0.0377
Trypanosoma cruzi small myristoylated protein 1-1 0.036 0.073 0.0784
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.2157
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.1342
Echinococcus multilocularis pyruvate kinase 0.0033 0.0024 0.0024
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Brugia malayi MH2 domain containing protein 0.0253 0.0499 0.0543
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0052 0.0094
Echinococcus multilocularis calmodulin 0.0116 0.0204 0.0204
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0542 0.1123 0.1221
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1135 0.2402 0.4207
Schistosoma mansoni calmodulin 0.0116 0.0204 0.0217

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 56.4 uM Concentration of the compound required to reduce the viability of uninfected MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 0.37 uM Concentration of the compound required to inhibit human immunodeficiency virus-1 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 3.6 uM Concentration of the compound required to reduce human cytomegalo virus(Davis) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) = 4.47 uM Concentration of the compound required to inhibit human immunodeficiency virus-2 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 6.3 uM Concentration of the compound required to reduce human cytomegalo virus(AD-169) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) > 22 uM Concentration of the compound required to inhibit HEL cell growth by 50% ChEMBL. 9022801
IC50 (functional) = 54.2 uM Concentration of the compound required to inhibit by 50% human immunodeficiency virus-2 induced syncytium formation upon coculturing persistently HIV-infected HUT-78 cells with MOLT-4 cells ChEMBL. 9022801
IC50 (functional) = 68 uM Concentration of the compound required to reduce herpes simplex virus-1TK( B2006) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) = 136 uM Concentration of the compound required to reduce herpes simplex virus-1TK (KOS) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) = 136 uM Concentration of the compound required to reduce herpes simplex virus-2(G) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce herpes simplex virus-1TK (VMW1837) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce vesicular stomatitis virus-inducted cytopathicity by 50% (HeLa cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce Coxsackie virus-inducted cytopathicity by 50% (HeLa cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal E6SM cell morphology ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal Hela cell morphology ChEMBL. 9022801

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9022801

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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