Detailed information for compound 513719

Basic information

Technical information
  • TDR Targets ID: 513719
  • Name: (2E)-2-[2-(4-chlorophenyl)-1-oxopyrrolo[3,4-b ]quinolin-3-ylidene]-N-(4-hydroxyphenyl)-N-me thylacetamide
  • MW: 455.892 | Formula: C26H18ClN3O3
  • H donors: 1 H acceptors: 4 LogP: 4.39 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)N(C(=O)/C=C/1\c2nc3ccccc3cc2C(=O)N1c1ccc(cc1)Cl)C
  • InChi: 1S/C26H18ClN3O3/c1-29(18-10-12-20(31)13-11-18)24(32)15-23-25-21(14-16-4-2-3-5-22(16)28-25)26(33)30(23)19-8-6-17(27)7-9-19/h2-15,31H,1H3/b23-15+
  • InChiKey: RTKWSEJAXAJHSA-HZHRSRAPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2E)-2-[2-(4-chlorophenyl)-1-oxo-pyrrolo[3,4-b]quinolin-3-ylidene]-N-(4-hydroxyphenyl)-N-methyl-acetamide
  • (2E)-2-[2-(4-chlorophenyl)-1-oxo-3-pyrrolo[3,4-b]quinolinylidene]-N-(4-hydroxyphenyl)-N-methylacetamide
  • (2E)-2-[2-(4-chlorophenyl)-1-oxo-pyrrolo[3,4-b]quinolin-3-ylidene]-N-(4-hydroxyphenyl)-N-methyl-ethanamide
  • (2E)-2-[2-(4-chlorophenyl)-1-keto-pyrrolo[3,4-b]quinolin-3-ylidene]-N-(4-hydroxyphenyl)-N-methyl-acetamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Peripheral-type benzodiazepine receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_129542 All targets in OG5_129542
Mycobacterium ulcerans tryptophan-rich sensory protein Get druggable targets OG5_129542 All targets in OG5_129542
Onchocerca volvulus Get druggable targets OG5_129542 All targets in OG5_129542
Onchocerca volvulus Get druggable targets OG5_129542 All targets in OG5_129542
Brugia malayi TspO/MBR family protein Get druggable targets OG5_129542 All targets in OG5_129542
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129542 All targets in OG5_129542
Onchocerca volvulus Get druggable targets OG5_129542 All targets in OG5_129542
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129542 All targets in OG5_129542
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129542 All targets in OG5_129542
Schistosoma mansoni peripheral-type benzodiazepine receptor Get druggable targets OG5_129542 All targets in OG5_129542
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129542 All targets in OG5_129542
Echinococcus multilocularis translocator protein Get druggable targets OG5_129542 All targets in OG5_129542
Echinococcus granulosus translocator protein Get druggable targets OG5_129542 All targets in OG5_129542
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Peripheral-type benzodiazepine receptor   169 aa 156 aa 25.6 %
Echinococcus granulosus vacuolar h atpase Peripheral-type benzodiazepine receptor   169 aa 137 aa 25.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.0062 0.0075 0.0198
Brugia malayi Thioredoxin reductase 0.0098 0.0154 0.0215
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3248 0.7102 1
Schistosoma mansoni chromobox protein 0.0249 0.0489 0.0685
Entamoeba histolytica calmodulin, putative 0.0089 0.0136 0.0436
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0003 0.0003
Brugia malayi aspartic protease BmAsp-2, identical 0.0079 0.0114 0.0158
Loa Loa (eye worm) hypothetical protein 0.0344 0.0698 0.098
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Echinococcus multilocularis calcium uptake protein 1 0.0092 0.0142 0.014
Loa Loa (eye worm) B-box zinc finger family protein 0.0038 0.0023 0.0029
Trypanosoma cruzi calmodulin, putative 0.0089 0.0136 0.0189
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.007 0.0094 0.025
Schistosoma mansoni hypothetical protein 0.0058 0.0066 0.0091
Trypanosoma brucei cysteine peptidase C (CPC) 0.1242 0.2678 0.723
Brugia malayi Papain family cysteine protease containing protein 0.0788 0.1678 0.236
Echinococcus multilocularis dnaJ subfamily B 0.0505 0.1053 0.1051
Echinococcus multilocularis programmed cell death protein 0.0098 0.0155 0.0153
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0039 0.0025 0.0361
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0177 0.0329 0.0461
Schistosoma mansoni pyruvate kinase 0.0036 0.0019 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Plasmodium vivax aspartyl proteinase, putative 0.0079 0.0114 0.0364
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0223 0.043 0.1157
Loa Loa (eye worm) blistered cuticle protein 3 0.0114 0.0192 0.0267
Leishmania major hypothetical protein, conserved 0.0223 0.043 0.1157
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Echinococcus multilocularis neuropeptide receptor A26 0.0352 0.0716 0.0714
Brugia malayi hypothetical protein 0.0072 0.0097 0.0134
Echinococcus granulosus lamin 0.0029 0.0003 0.0002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0115 0.0192 0.019
Plasmodium falciparum plasmepsin III 0.0079 0.0114 0.0364
Onchocerca volvulus 0.0079 0.0114 0.0226
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.0061 0.0059
Trichomonas vaginalis calcium binding proteins, putative 0.0089 0.0136 0.0273
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0344 0.0698 0.098
Echinococcus multilocularis allatostatin A receptor 0.0055 0.0061 0.0059
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0033 0.0044
Giardia lamblia Cathepsin B precursor 0.1242 0.2678 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0528 0.107
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.0061 0.0083
Leishmania major calcineurin B subunit, putative 0.0089 0.0136 0.0362
Schistosoma mansoni opsin-like receptor 0.0055 0.0061 0.0083
Brugia malayi Trypsin family protein 0.0058 0.0066 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0033 0.0044
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0177 0.0329 0.0327
Brugia malayi cathepsin Z-like cysteine proteinase 0.0344 0.0698 0.098
Mycobacterium ulcerans tryptophan-rich sensory protein 0.0322 0.0649 1
Brugia malayi latrophilin 2 splice variant baaae 0.0514 0.1073 0.1509
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0202 0.0385 0.1034
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0038
Leishmania major hypothetical protein, conserved 0.0111 0.0184 0.0491
Loa Loa (eye worm) hypothetical protein 0.0322 0.0649 0.0911
Onchocerca volvulus Peroxidase homolog 0.0114 0.0192 0.0384
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0006 0.001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0033 0.0044
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0082 0.0119 0.0165
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Schistosoma mansoni cathepsin D (A01 family) 0.0988 0.2119 0.2982
Brugia malayi Cathepsin L-like cysteine proteinase 0.098 0.21 0.2954
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0038 0.0022 0.0396
Onchocerca volvulus Peroxidasin homolog 0.0114 0.0192 0.0384
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.0061 0.0083
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0039 0.0025 0.0361
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.0791 0.1604
Toxoplasma gondii target of rapamycin (TOR), putative 0.0062 0.0075 0.0238
Trypanosoma cruzi PAB1-binding protein , putative 0.0111 0.0184 0.0256
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0006 0.0004
Echinococcus multilocularis calpain 0.0673 0.1424 0.1422
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0606 0.1275 0.1792
Loa Loa (eye worm) hypothetical protein 0.0322 0.0649 0.0911
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0057 0.0066 0.1302
Onchocerca volvulus 0.0114 0.0192 0.0384
Toxoplasma gondii PHD-finger domain-containing protein 0.0216 0.0414 0.134
Echinococcus multilocularis jumonji domain containing 1A 0.007 0.0093 0.0091
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0032
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0537 0.1124 0.158
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1511 0.3273 0.3271
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3248 0.7102 1
Schistosoma mansoni calpain-7 (C02 family) 0.0679 0.1438 0.2022
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.014 0.0248 0.08
Brugia malayi Inositol-1 0.0036 0.0018 0.0022
Brugia malayi Animal haem peroxidase family protein 0.0114 0.0192 0.0267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.014 0.0247 0.0497
Loa Loa (eye worm) hypothetical protein 0.0147 0.0263 0.0368
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0061 0.0083
Echinococcus granulosus enteropeptidase 0.0058 0.0066 0.0091
Plasmodium falciparum ataxin-2 like protein, putative 0.0111 0.0184 0.0591
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0033 0.0044
Schistosoma mansoni zinc finger protein 0.0169 0.0311 0.0435
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0014 0.0038
Echinococcus multilocularis caspase 2 0.0058 0.0066 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0788 0.1678 0.4527
Giardia lamblia Histone acetyltransferase GCN5 0.0059 0.007 0.0253
Echinococcus granulosus cathepsin l cysteine peptidase 0.1424 0.308 0.4334
Plasmodium falciparum plasmepsin I 0.0335 0.0678 0.2198
Echinococcus granulosus calpain 5 0.0673 0.1424 0.2003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0203 0.0387 0.0542
Schistosoma mansoni peptidyl-glycine monooxygenase 0.1451 0.3139 0.4418
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0033 0.0044
Schistosoma mansoni jumonji domain containing protein 0.007 0.0093 0.0128
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.0061 0.0118
Echinococcus granulosus orexin receptor type 2 0.0055 0.0061 0.0083
Echinococcus granulosus JmjC domain containing protein 4 0.007 0.0093 0.0128
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0202 0.0385 0.1034
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0039 0.0025 0.0462
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0113 0.1076
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0092 0.0142 0.0197
Schistosoma mansoni hypothetical protein 0.0062 0.0075 0.0103
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.009
Echinococcus granulosus cathepsin l1 0.098 0.21 0.2954
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0956 0.2047 0.2879
Leishmania major centrin, putative,caltractin, putative 0.0089 0.0136 0.0362
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0029 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Echinococcus granulosus lysine specific demethylase 5A 0.0279 0.0554 0.0777
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0537 0.1124 0.3031
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0089 0.0136 0.0189
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0039 0.0025 0.0361
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0073 0.01 0.0139
Trichomonas vaginalis chromobox protein, putative 0.015 0.027 0.0546
Trypanosoma brucei centrin, putative 0.0089 0.0136 0.0362
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0164 0.03 0.042
Loa Loa (eye worm) hypothetical protein 0.0144 0.0256 0.0358
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi neuropeptide F receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Giardia lamblia Hypothetical protein 0.0344 0.0698 0.2599
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0014 0.0032
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0902 0.1929 0.5205
Plasmodium falciparum plasmepsin VIII, putative 0.0079 0.0114 0.0364
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0344 0.0698 0.098
Trichomonas vaginalis calcium binding protein, putative 0.0089 0.0136 0.0273
Trichomonas vaginalis Heterochromatin protein, putative 0.0041 0.0029 0.0055
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0089 0.0136 0.0189
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0057 0.0066 0.0207
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0216 0.0414 0.0581
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Schistosoma mansoni hypothetical protein 0.0315 0.0633 0.0888
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Leishmania major calmodulin, putative 0.0089 0.0136 0.0362
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.0061 0.0059
Trypanosoma cruzi I/6 autoantigen, putative 0.0089 0.0136 0.0189
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0223 0.043 0.1157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0017
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0014 0.0038
Entamoeba histolytica cysteine protease, putative 0.1424 0.308 1
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0335 0.0678 0.0677
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0014 0.0182
Entamoeba histolytica acyl-CoA synthetase, putative 0.0039 0.0025 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0002
Echinococcus granulosus histone acetyltransferase KAT2B 0.0084 0.0124 0.0173
Echinococcus granulosus geminin 0.1083 0.2328 0.3277
Echinococcus granulosus survival motor neuron protein 1 0.0326 0.0659 0.0925
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0057 0.0066 0.009
Echinococcus multilocularis methyl CpG binding domain protein 2 0.014 0.0249 0.0247
Giardia lamblia Cathepsin L precursor 0.0344 0.0698 0.2599
Trypanosoma cruzi hypothetical protein, conserved 0.0361 0.0735 0.1032
Brugia malayi Papain family cysteine protease containing protein 0.0344 0.0698 0.098
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0572 0.1201 0.12
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0053 0.0057 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis neuronal calcium sensor 0.0089 0.0136 0.0134
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0053 0.0057 0.0111
Echinococcus granulosus cathepsin b 0.3248 0.7102 1
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0089 0.0136 0.0134
Trypanosoma cruzi cysteine peptidase, putative 0.1424 0.308 0.4334
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Mycobacterium tuberculosis Conserved protein 0.0079 0.0113 0.1076
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0315 0.0635 0.1709
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0019 0.0024
Trichomonas vaginalis chromobox protein, putative 0.0249 0.0489 0.0989
Brugia malayi hypothetical protein 0.013 0.0226 0.0315
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1255 0.3386
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0062 0.0075 0.0103
Echinococcus granulosus histone acetyltransferase MYST2 0.0164 0.03 0.042
Trypanosoma cruzi cruzipain precursor, putative 0.1729 0.3753 0.5283
Entamoeba histolytica cysteine proteinase, putative 0.1424 0.308 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0113 0.0157
Schistosoma mansoni calpain-2 (C02 family) 0.0315 0.0633 0.0888
Brugia malayi Protein cec-1. 0.0041 0.0029 0.0038
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0061 0.0059
Loa Loa (eye worm) PHD-finger family protein 0.0216 0.0414 0.0581
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0019 0.0056
Entamoeba histolytica hypothetical protein 0.0164 0.0301 0.0973
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0344 0.0698 0.1414
Echinococcus granulosus translocator protein 0.0322 0.0649 0.0911
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0033 0.0044
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0188 0.0353 0.0351
Onchocerca volvulus 0.1424 0.308 0.6256
Brugia malayi intermediate filament protein 0.0029 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0238 0.0464 0.0651
Trichomonas vaginalis calcium binding protein, putative 0.0089 0.0136 0.0273
Schistosoma mansoni opsin-like receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.1063 0.2285 0.3215
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0025 0.0361
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.0061 0.0083
Loa Loa (eye worm) calpain 0.0673 0.1424 0.2003
Plasmodium falciparum calpain 0.0315 0.0633 0.205
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0223 0.043 0.0603
Schistosoma mansoni cellular tumor antigen P53 0.0147 0.0263 0.0368
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0061 0.0083
Entamoeba histolytica hypothetical protein 0.0164 0.0301 0.0973
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0344 0.0698 0.098
Loa Loa (eye worm) hypothetical protein 0.0079 0.0113 0.0157
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0277 0.0549 0.0771
Onchocerca volvulus 0.0062 0.0075 0.0147
Brugia malayi KE2 family protein 0.0061 0.0074 0.0101
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0071 0.0097 0.0133
Onchocerca volvulus 0.0041 0.0029 0.0053
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.0005
Echinococcus multilocularis glycoprotein Antigen 5 0.0058 0.0066 0.0065
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0657 0.1389 0.1954
Plasmodium falciparum prefoldin subunit 6, putative 0.0061 0.0074 0.0234
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0344 0.0698 0.098
Loa Loa (eye worm) hypothetical protein 0.004 0.0028 0.0037
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0223 0.043 0.8863
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.0061 0.0059
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0017
Plasmodium vivax SET domain protein, putative 0.0285 0.0568 0.1841
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Entamoeba histolytica cysteine proteinase, putative 0.098 0.21 0.6816
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1242 0.2678 0.377
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.0061 0.0083
Trypanosoma brucei calpain-like protein, putative 0.0673 0.1424 0.3841
Giardia lamblia Cathepsin L precursor 0.0344 0.0698 0.2599
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0114 0.019 0.0265
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0025 0.0361
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0084 0.0124 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Echinococcus granulosus jumonji domain containing 1A 0.007 0.0093 0.0128
Echinococcus granulosus hypothetical protein 0.0055 0.0061 0.0083
Echinococcus multilocularis histone acetyltransferase MYST2 0.0164 0.03 0.0298
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0033 0.0044
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0089 0.0136 0.0189
Trypanosoma cruzi kinesin, putative 0.0359 0.073 0.1026
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.0791 0.1604
Trypanosoma cruzi centrin, putative 0.0098 0.0155 0.0216
Brugia malayi B-box zinc finger family protein 0.0038 0.0023 0.0029
Loa Loa (eye worm) matrixin family protein 0.0053 0.0056 0.0075
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0113 0.1718
Loa Loa (eye worm) hypothetical protein 0.0216 0.0414 0.0581
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi aspartic protease BmAsp-1, identical 0.0079 0.0114 0.0158
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.0061 0.0083
Echinococcus granulosus transmembrane protease serine 3 0.0058 0.0066 0.0091
Schistosoma mansoni bromodomain containing protein 0.0529 0.1105 0.1554
Loa Loa (eye worm) calpain family protein 1 0.1063 0.2285 0.3215
Onchocerca volvulus 0.0079 0.0114 0.0226
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0003 0.0002
Schistosoma mansoni amine GPCR 0.0055 0.0061 0.0083
Leishmania major calpain protease-like protein 0.0315 0.0633 0.1704
Brugia malayi GnHR receptor homolog 0.0055 0.0061 0.0083
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0164 0.03 0.0298
Giardia lamblia Cathepsin B precursor 0.0344 0.0698 0.2599
Loa Loa (eye worm) thioredoxin reductase 0.0098 0.0154 0.0215
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni amine GPCR 0.0055 0.0061 0.0083
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0061 0.0083
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0014 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0061 0.0059
Echinococcus multilocularis tar DNA binding protein 0.0348 0.0708 0.0706
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0597 0.1255 0.3386
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0019 0.0024
Schistosoma mansoni neuronal calcium sensor 0.0089 0.0136 0.0189
Echinococcus granulosus intermediate filament protein 0.0029 0.0003 0.0002
Trypanosoma cruzi calmodulin, putative 0.0089 0.0136 0.0189
Brugia malayi calpain 5 0.0359 0.073 0.1026
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0113 0.0157
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0082 0.0119 0.0316
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0348 0.0708 0.0994
Onchocerca volvulus Heterochromatin protein 1 homolog 0.015 0.027 0.0544
Echinococcus multilocularis survival motor neuron protein 1 0.0326 0.0659 0.0657
Brugia malayi Dopamine receptor 0.0055 0.0061 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0956 0.2047 0.5523
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0059 0.0116
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0003 0.0003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.0061 0.0059
Echinococcus multilocularis programmed cell death protein 0.0098 0.0155 0.0153
Trypanosoma cruzi cysteine peptidase, putative 0.1707 0.3704 0.5213
Onchocerca volvulus 0.0055 0.0061 0.0118
Onchocerca volvulus Cathepsin F homolog 0.1424 0.308 0.6256
Loa Loa (eye worm) hypothetical protein 0.098 0.21 0.2954
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0071 0.0097 0.0133
Brugia malayi G-protein coupled receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0344 0.0698 0.098
Echinococcus multilocularis brain tumor protein 0.0038 0.0023 0.0021
Leishmania major cysteine peptidase A (CPA) 0.1424 0.308 0.8314
Trypanosoma brucei calpain-like protein, putative 0.0956 0.2047 0.5523
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0223 0.043 0.4095
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0877 0.1873 0.5054
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.0791 0.1604
Echinococcus granulosus lysine specific demethylase 6a 0.007 0.0093 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0074 0.0146
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0019 0.0056
Toxoplasma gondii cathepsin B 0.1242 0.2678 0.8697
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1424 0.308 0.6257
Plasmodium vivax hypothetical protein, conserved 0.0216 0.0414 0.134
Echinococcus multilocularis calbindin 32 0.0092 0.0142 0.014
Onchocerca volvulus 0.0058 0.0066 0.013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0213 0.041 0.0574
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0089 0.0136 0.0134
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0057 0.0066 0.0207
Loa Loa (eye worm) hypothetical protein 0.0077 0.0108 0.015
Mycobacterium tuberculosis Probable conserved membrane protein 0.0038 0.0023 0.0216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0033 0.0044
Toxoplasma gondii calmodulin CAM1 0.0092 0.0142 0.0455
Schistosoma mansoni amine GPCR 0.0055 0.0061 0.0083
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0448 0.0928 0.1304
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0033 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0047 0.0091
Plasmodium falciparum plasmepsin V 0.0079 0.0114 0.0364
Brugia malayi Trypsin family protein 0.0058 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Leishmania major cathepsin L-like protease 0.1424 0.308 0.8314
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0046 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0344 0.0698 0.1414
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0427 0.088 0.1237
Loa Loa (eye worm) hypothetical protein 0.0079 0.0114 0.0158
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0014 0.1843
Loa Loa (eye worm) hypothetical protein 0.1422 0.3076 0.4329
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0006 0.0005
Echinococcus granulosus snurportin 1 0.0233 0.0453 0.0635
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0071 0.0097 0.0192
Onchocerca volvulus 0.0058 0.0066 0.013
Entamoeba histolytica cysteine protease, putative 0.0344 0.0698 0.2261
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3248 0.7102 1
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0025 0.0033
Loa Loa (eye worm) RING finger protein nhl-1 0.0038 0.0023 0.0029
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0855 0.1826 0.4927
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.043 0.0603
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0029 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0008
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0239 0.0466 0.0464
Trypanosoma cruzi ISWI complex protein 0.0126 0.0217 0.0303
Echinococcus granulosus Mastin 0.0058 0.0066 0.0091
Onchocerca volvulus 0.0035 0.0017 0.003
Onchocerca volvulus 0.0322 0.0649 0.1314
Plasmodium falciparum serine repeat antigen 7 0.0344 0.0698 0.2261
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0344 0.0698 0.2261
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0019 0.0033
Entamoeba histolytica hypothetical protein 0.0041 0.0029 0.0088
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0033 0.0044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0033
Loa Loa (eye worm) calpain 5 0.0359 0.073 0.1026
Echinococcus multilocularis thioredoxin glutathione reductase 0.0098 0.0154 0.0153
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi glutathione reductase 0.0098 0.0154 0.0215
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0089 0.0136 0.0436
Toxoplasma gondii aspartyl protease ASP1 0.0335 0.0678 0.2198
Toxoplasma gondii cathepsin CPL 0.1424 0.308 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0344 0.0698 0.2261
Plasmodium falciparum plasmepsin IV 0.0335 0.0678 0.2198
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0038 0.0022 0.0211
Brugia malayi SET domain containing protein 0.0052 0.0054 0.0073
Loa Loa (eye worm) calpain D 0.0315 0.0633 0.0888
Onchocerca volvulus 0.0058 0.0066 0.013
Leishmania major 4-coumarate:coa ligase-like protein 0.0039 0.0025 0.0063
Schistosoma mansoni hypothetical protein 0.0089 0.0136 0.0189
Schistosoma mansoni SET domain protein 0.0029 0.0003 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0033 0.0044
Trypanosoma brucei calmodulin, putative 0.0089 0.0136 0.0362
Schistosoma mansoni tar DNA-binding protein 0.0348 0.0708 0.0994
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Loa Loa (eye worm) NCL-1 protein 0.0038 0.0023 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Brugia malayi ORL1-like opioid receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0115 0.0159
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0033 0.0044
Trichomonas vaginalis centrin, putative 0.0089 0.0136 0.0273
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 1
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0061 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Brugia malayi Valyl-tRNA synthetase 0.0041 0.0029 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis prefoldin subunit 6 0.0061 0.0074 0.0072
Schistosoma mansoni hypothetical protein 0.0233 0.0453 0.0635
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0537 0.1124 0.158
Plasmodium falciparum serine repeat antigen 2 0.0344 0.0698 0.2261
Echinococcus granulosus chromobox protein 1 0.0249 0.0489 0.0685
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0238 0.0464 0.0651
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0039 0.0025 0.0241
Entamoeba histolytica cysteine proteinase, putative 0.0788 0.1678 0.5445
Plasmodium falciparum acyl-CoA synthetase 0.0029 0.0004 0.0005
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0099 0.0156 0.0154
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0071 0.0097 0.0256
Echinococcus multilocularis lysine specific demethylase 5A 0.0261 0.0515 0.0513
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0136 0.0273
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0149 0.0269 0.0542
Trichomonas vaginalis conserved hypothetical protein 0.0361 0.0735 0.149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.004 0.0078
Plasmodium falciparum ataxin-2 like protein, putative 0.0111 0.0184 0.0591
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Echinococcus multilocularis peroxidasin 0.0114 0.0192 0.019
Entamoeba histolytica hypothetical protein 0.0041 0.0029 0.0088
Echinococcus multilocularis sex peptide receptor 0.0055 0.0061 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Brugia malayi Bromodomain containing protein 0.0321 0.0647 0.0908
Plasmodium vivax unspecified product 0.0788 0.1678 0.5445
Brugia malayi Peroxidasin 0.0114 0.0192 0.0267
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.0061 0.0083
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0053 0.0057 0.0077
Echinococcus granulosus neuropeptide receptor 0.0055 0.0061 0.0083
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0019 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0344 0.0698 0.1414
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0033 0.0044
Leishmania major pyruvate kinase 0.0036 0.0019 0.0047
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0073 0.0099 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0084 0.0167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0002
Entamoeba histolytica cysteine protease, putative 0.0344 0.0698 0.2261
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Echinococcus multilocularis phd:f box containing protein 0.007 0.0093 0.0091
Brugia malayi Muscleblind-like protein 0.0114 0.019 0.0265
Leishmania major DNA polymerase eta, putative 0.0034 0.0014 0.0033
Onchocerca volvulus 0.0055 0.0061 0.0118
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Plasmodium falciparum serine repeat antigen 3 0.0344 0.0698 0.2261
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.0791 0.1604
Brugia malayi AF-10 protein 0.007 0.0094 0.013
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Plasmodium falciparum JmjC domain-containing protein, putative 0.007 0.0093 0.0294
Loa Loa (eye worm) hypothetical protein 0.0089 0.0136 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.0698 0.1414
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0325 0.0657 0.1769
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0055 0.0061 0.0083
Trypanosoma cruzi cysteine peptidase, putative 0.1707 0.3704 0.5213
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0427 0.088 0.1237
Onchocerca volvulus 0.0055 0.0061 0.0118
Schistosoma mansoni neuropeptide receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis cathepsin b 0.3248 0.7102 0.7102
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0391 0.0801 0.1126
Echinococcus granulosus EF HAND 1 calcium binding site 0.0089 0.0136 0.0189
Schistosoma mansoni cathepsin F (C01 family) 0.098 0.21 0.2954
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0025 0.0241
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0277 0.0549 0.0547
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0223 0.043 0.4095
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0033 0.0031
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0344 0.0698 0.2261
Toxoplasma gondii microneme protein, putative 0.0029 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0017
Onchocerca volvulus 0.0055 0.0061 0.0118
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0003 0.0001
Brugia malayi Eukaryotic aspartyl protease family protein 0.0079 0.0114 0.0158
Loa Loa (eye worm) MH2 domain-containing protein 0.0254 0.0499 0.07
Giardia lamblia Cathepsin B precursor 0.1242 0.2678 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0041 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0061 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.0698 0.1414
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1424 0.308 0.4334
Brugia malayi steroid hormone receptor 0.0043 0.0033 0.0044
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Brugia malayi hypothetical protein 0.0111 0.0184 0.0256
Onchocerca volvulus 0.0055 0.0061 0.0118
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0038
Brugia malayi Latrophilin receptor protein 2 0.0238 0.0464 0.0651
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0028 0.0026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0006 0.0005
Plasmodium falciparum plasmepsin VII 0.0079 0.0114 0.0364
Loa Loa (eye worm) TK/ROR protein kinase 0.0062 0.0075 0.0103
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0006 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Brugia malayi MH2 domain containing protein 0.0254 0.0499 0.07
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0008
Leishmania major cathepsin L-like protease 0.1424 0.308 0.8314
Leishmania major cathepsin L-like protease 0.1707 0.3704 1
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0019 0.0033
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1242 0.2678 0.723
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0282 0.0562 0.1512
Leishmania major phospholipase c-like protein 0.0089 0.0136 0.0362
Schistosoma mansoni calmodulin 0.0089 0.0136 0.0189
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0069 0.0091 0.029
Leishmania major hypothetical protein, conserved 0.0223 0.043 0.1157
Echinococcus multilocularis lysosomal alpha glucosidase 0.0115 0.0192 0.019
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Echinococcus granulosus SAM and MBT domain containing protein 0.0144 0.0256 0.0358
Brugia malayi G-protein coupled receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1242 0.2678 0.5441
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0014 0.0032
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0902 0.1929 0.5205
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0055 0.0061 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.0698 0.1414
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0223 0.043 0.0603
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.005 0.0098
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.007 0.0093 0.0128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0344 0.0698 0.098
Plasmodium falciparum cysteine proteinase falcipain 3 0.1424 0.308 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0006 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0039 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0344 0.0698 0.098
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0089 0.0136 0.0189
Echinococcus granulosus EF hand domain containing family member A2 0.0092 0.0142 0.0197
Echinococcus granulosus histone lysine methyltransferase setb 0.0426 0.0878 0.1234
Loa Loa (eye worm) animal heme peroxidase 0.0114 0.0192 0.0267
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Giardia lamblia GTOR 0.0082 0.0119 0.0437
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0036 0.0048
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0344 0.0698 0.098
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0014 0.0038
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0033 0.0044
Plasmodium falciparum serine repeat antigen 6 0.0344 0.0698 0.2261
Brugia malayi Cathepsin L-like precursor 0.1424 0.308 0.4334
Trypanosoma cruzi cysteine peptidase, putative 0.1707 0.3704 0.5213
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0344 0.0698 0.1414
Onchocerca volvulus 0.0322 0.0649 0.1314
Schistosoma mansoni bromodomain containing protein 0.0043 0.0033 0.0044
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0855 0.1826 0.4927
Echinococcus granulosus cathepsin L 0.0788 0.1678 0.236
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0157 0.0316
Loa Loa (eye worm) phosphatidylinositol 3 0.0247 0.0484 0.0679
Trypanosoma brucei trypanothione reductase 0.0098 0.0154 0.0412
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0223 0.043 0.4095
Schistosoma mansoni methyl-cpg binding protein mbd 0.014 0.0249 0.0348
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Brugia malayi hypothetical protein 0.0077 0.0108 0.015
Echinococcus granulosus lamin dm0 0.0029 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0038 0.0023 0.0029
Leishmania major small myristoylated protein-3, putative 0.0325 0.0657 0.1769
Onchocerca volvulus 0.0055 0.0061 0.0118
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0203 0.0387 0.0542
Echinococcus granulosus tachykinin peptides receptor 99D 0.152 0.3292 0.4634
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0082 0.0119 0.0316
Echinococcus multilocularis tachykinin peptides receptor 99D 0.152 0.3292 0.3291
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.001
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni jumonji domain containing protein 0.0561 0.1176 0.1654
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.0061 0.0083
Echinococcus granulosus tar DNA binding protein 0.0348 0.0708 0.0994
Schistosoma mansoni peptidylglycine monooxygenase 0.0038 0.0023 0.0029
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0014 0.0039
Onchocerca volvulus Matrilysin homolog 0.0053 0.0056 0.0107
Onchocerca volvulus 0.0055 0.0061 0.0118
Loa Loa (eye worm) jmjC domain-containing protein 0.0445 0.0921 0.1294
Echinococcus granulosus calbindin 32 0.0092 0.0142 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0041 0.0078
Onchocerca volvulus 0.1424 0.308 0.6256
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS18 0.0038 0.0023 0.0216
Trypanosoma brucei centrin-3 0.0098 0.0155 0.0414
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Loa Loa (eye worm) MBCTL1 0.0164 0.03 0.042
Brugia malayi Melatonin receptor type 1A 0.0055 0.0061 0.0083
Brugia malayi Cathepsin L-like precursor 0.0444 0.0919 0.1292
Brugia malayi nuclear receptor NHR-88 0.0043 0.0033 0.0044
Loa Loa (eye worm) B-box zinc finger family protein 0.0038 0.0023 0.0029
Echinococcus granulosus tumor protein p63 0.1004 0.2153 0.3029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0238 0.0464 0.0462
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Trypanosoma brucei Calpain-like protein CALP1.3 0.0537 0.1124 0.3031
Mycobacterium tuberculosis Conserved protein 0.0079 0.0113 0.1076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0099 0.0156 0.0218
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0041 0.0029 0.0088
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0113 0.0157
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0113 0.1076
Schistosoma mansoni histamine h1 receptor 0.0055 0.0061 0.0083
Leishmania major 4-coumarate:coa ligase-like protein 0.0039 0.0025 0.0063
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.0154 0.0215
Onchocerca volvulus Dual oxidase homolog 0.0114 0.0192 0.0384
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis snurportin 1 0.0233 0.0453 0.0451
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0296 0.0592 0.059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Mycobacterium tuberculosis Probable oxidoreductase 0.0248 0.0485 0.4617
Brugia malayi larval opioid receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi Proteasome A-type and B-type family protein 0.0071 0.0097 0.0133
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0019 0.0047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0444 0.0919 0.1292
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1985 0.4316 0.6076
Plasmodium vivax aspartyl protease, putative 0.0079 0.0114 0.0364
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0002
Entamoeba histolytica calcium binding family protein 0.0089 0.0136 0.0436
Onchocerca volvulus 0.0055 0.0061 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.005 0.0098
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0537 0.1124 0.158
Echinococcus multilocularis EF hand domain containing family member A2 0.0089 0.0136 0.0134
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0082 0.0119 0.0165
Loa Loa (eye worm) hypothetical protein 0.098 0.21 0.2954
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0075 0.0103
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0038 0.0023 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0039 0.0074
Schistosoma mansoni mixed-lineage leukemia protein mll 0.009 0.0137 0.019
Trichomonas vaginalis calpain, putative 0.0315 0.0633 0.1282
Echinococcus granulosus serotonin receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis muscleblind protein 0.0114 0.019 0.0188
Onchocerca volvulus 0.0079 0.0113 0.0224
Brugia malayi hypothetical protein 0.0326 0.0659 0.0925
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.012 0.0204 0.0655
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0315 0.0633 0.1282
Brugia malayi CXXC zinc finger family protein 0.0035 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni cathepsin S (C01 family) 0.0344 0.0698 0.098
Onchocerca volvulus 0.0055 0.0061 0.0118
Echinococcus granulosus chromobox protein 2 0.0041 0.0029 0.0038
Schistosoma mansoni centrin 0.0089 0.0136 0.0189
Toxoplasma gondii histone lysine methyltransferase SET1 0.0103 0.0165 0.053
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0071 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0033 0.0044
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0956 0.2047 0.2879
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0003 0.0003
Trypanosoma brucei DNA polymerase beta thumb, putative 0.006 0.0071 0.0188
Schistosoma mansoni biogenic amine receptor 0.0055 0.0061 0.0083
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Echinococcus granulosus g protein coupled receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0113 0.0111
Brugia malayi Hypothetical RING finger protein F54G8.4 in chromosome III 0.0038 0.0023 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0315 0.0633 0.0888
Schistosoma mansoni chromobox protein 0.0249 0.0489 0.0685
Trypanosoma cruzi hypothetical protein, conserved 0.0361 0.0735 0.1032
Echinococcus granulosus GPCR family 2 0.0238 0.0464 0.0651
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0692 0.1465 0.2061
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.0061 0.0083
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0075 0.0104 0.0381
Echinococcus multilocularis chromobox protein 1 0.0249 0.0489 0.0487
Schistosoma mansoni hypothetical protein 0.0238 0.0464 0.0651
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0029 0.0003 0.0029
Schistosoma mansoni hypothetical protein 0.0238 0.0464 0.0651
Echinococcus granulosus dnaJ subfamily B 0.0505 0.1053 0.148
Plasmodium falciparum plasmepsin IX 0.0079 0.0114 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Giardia lamblia Hypothetical protein 0.0344 0.0698 0.2599
Loa Loa (eye worm) hypothetical protein 0.0341 0.0691 0.0971
Schistosoma mansoni hypothetical protein 0.0164 0.0301 0.0422
Echinococcus multilocularis cpg binding protein 0.0053 0.0056 0.0054
Echinococcus granulosus methyl CpG binding domain protein 2 0.014 0.0249 0.0348
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0028 0.0037
Echinococcus granulosus chromobox protein 1 0.0249 0.0489 0.0685
Trypanosoma brucei unspecified product 0.0223 0.043 0.1157
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.0791 0.1604
Onchocerca volvulus 0.1424 0.308 0.6256
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Echinococcus granulosus pyruvate kinase 0.0036 0.0019 0.0024
Trypanosoma cruzi cruzipain precursor, putative 0.1707 0.3704 0.5213
Loa Loa (eye worm) phosphatidylinositol 3 0.0082 0.0119 0.0165
Schistosoma mansoni peroxidasin 0.0114 0.0192 0.0267
Plasmodium vivax hypothetical protein, conserved 0.0092 0.0142 0.0455
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0315 0.0633 0.1282
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0282 0.0562 0.0788
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0058 0.0066 0.0065
Onchocerca volvulus Matrix metalloproteinase homolog 0.0053 0.0056 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.004 0.0078
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.006 0.0071 0.0098
Schistosoma mansoni alpha-glucosidase 0.0099 0.0157 0.0218
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0019 0.0335
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0084 0.0124 0.0398
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0033 0.0044
Schistosoma mansoni hypothetical protein 0.0061 0.0074 0.0101
Echinococcus granulosus peptidase Clp S14 family 0.0038 0.0022 0.0028
Plasmodium vivax acyl-CoA synthetase, putative 0.0029 0.0004 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0111 0.0184 0.0256
Trypanosoma brucei hypothetical protein 0.0597 0.1255 0.3386
Schistosoma mansoni hypothetical protein 0.0055 0.0061 0.0083
Onchocerca volvulus 0.0055 0.0061 0.0118
Schistosoma mansoni methyl-cpg binding protein mbd 0.014 0.0249 0.0348
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0084 0.0124 0.0398
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0499 0.104 0.1462
Onchocerca volvulus 0.0079 0.0113 0.0224
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0127 0.022 0.0307
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0033 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0203 0.0387 0.0542
Echinococcus multilocularis geminin 0.1083 0.2328 0.2327
Onchocerca volvulus 0.0322 0.0649 0.1314
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0115 0.0192 0.0268
Schistosoma mansoni thyroid hormone receptor 0.022 0.0423 0.0593
Giardia lamblia PHD finger protein 15 0.0216 0.0414 0.1541
Entamoeba histolytica calpain family cysteine protease, putative 0.0315 0.0633 0.205
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0033 0.0031
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0537 0.1124 0.158
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0033 0.0044
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0248 0.0485 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0059 0.007 0.022
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0239 0.0466 0.0654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0788 0.1678 0.4527
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1511 0.3273 0.4606
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0014 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0079 0.0113 0.0157
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0344 0.0698 0.2261
Trypanosoma brucei calmodulin, putative 0.0092 0.0142 0.0378
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0004 0.0024
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0014 0.1639
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0113 0.0157
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0019 0.0035
Loa Loa (eye worm) hypothetical protein 0.0752 0.1598 0.2248
Loa Loa (eye worm) hypothetical protein 0.0111 0.0184 0.0256
Echinococcus multilocularis cathepsin L cysteine protease 0.1424 0.308 0.3078
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0003 0.0003
Loa Loa (eye worm) animal heme peroxidase 0.0114 0.0192 0.0267
Echinococcus multilocularis lysine specific demethylase 6a 0.007 0.0093 0.0091
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0344 0.0698 0.2599
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0087 0.0132 0.013
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0059 0.0068 0.0093
Brugia malayi Calmodulin-like protein 0.0089 0.0136 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0113 0.0157
Loa Loa (eye worm) hypothetical protein 0.0514 0.1073 0.1509
Trypanosoma cruzi cysteine protease, putative 0.0788 0.1678 0.236
Echinococcus granulosus zinc finger protein 0.0169 0.0311 0.0435
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0041 0.0029 0.0038
Schistosoma mansoni mitochondrial solute carrier 0.0089 0.0136 0.0189
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0335 0.0678 0.0953
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0238 0.0464 0.0462
Giardia lamblia Cathepsin L-like protease 0.0344 0.0698 0.2599
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0065
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.0061 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Plasmodium falciparum cysteine repeat modular protein 1 0.0062 0.0075 0.0238
Brugia malayi Hemopexin family protein 0.0034 0.0014 0.0016
Echinococcus granulosus allatostatin A receptor 0.0055 0.0061 0.0083
Trypanosoma cruzi target of rapamycin kinase 3 0.0066 0.0084 0.0116
Schistosoma mansoni pyruvate kinase 0.0036 0.0019 0.0024
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0204 0.0388 0.0544
Loa Loa (eye worm) hypothetical protein 0.0088 0.0134 0.0185
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0033 0.0031
Onchocerca volvulus 0.0034 0.0014 0.0022
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1422 0.3076 0.4329
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0113 0.1076
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0061 0.0083
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0019 0.0267
Echinococcus granulosus neuropeptide receptor 0.0055 0.0061 0.0083
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Giardia lamblia Cathepsin L precursor 0.0344 0.0698 0.2599
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0344 0.0698 0.2599
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0788 0.1678 0.236
Trichomonas vaginalis calcineurin B subunit, putative 0.0089 0.0136 0.0273
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0344 0.0698 0.2599
Echinococcus multilocularis enteropeptidase 0.0058 0.0066 0.0065
Echinococcus granulosus microtubule associated protein 2 0.2962 0.6471 0.9111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.0698 0.1414
Echinococcus multilocularis calpain 7 (C02 family) 0.0673 0.1424 0.1422
Toxoplasma gondii aspartyl protease ASP3 0.0079 0.0114 0.0364
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0033 0.0044
Brugia malayi Animal haem peroxidase family protein 0.0114 0.0192 0.0267
Brugia malayi beta-lactamase family protein 0.0079 0.0113 0.0157
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0361 0.0735 0.198
Trypanosoma brucei small myristoylated protein 1-2 0.0384 0.0786 0.2119
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0282 0.0562 0.1512
Schistosoma mansoni hypothetical protein 0.0505 0.1053 0.148
Toxoplasma gondii centrin 0.0089 0.0136 0.0436
Onchocerca volvulus 0.0055 0.0061 0.0118
Trypanosoma brucei calpain, putative 0.0597 0.1255 0.3386
Schistosoma mansoni calpain (C02 family) 0.0673 0.1424 0.2003
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0025 0.0361
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0061 0.0083
Brugia malayi EF hand family protein 0.0092 0.0142 0.0197
Leishmania major hypothetical protein, conserved 0.0223 0.043 0.1157
Giardia lamblia Cathepsin L precursor 0.0344 0.0698 0.2599
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0029 0.0055
Onchocerca volvulus Peroxidasin homolog 0.0114 0.0192 0.0384
Onchocerca volvulus 0.0029 0.0003 0.0001
Leishmania major centrin, putative 0.0089 0.0136 0.0362
Loa Loa (eye worm) CHromoDomain protein family member 0.0059 0.0068 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0033 0.0044
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0572 0.1201 0.1689
Echinococcus granulosus proteasome prosome macropain 0.0071 0.0097 0.0133
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0087 0.013 0.018
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Entamoeba histolytica calpain large subunit domain III containing protein 0.0359 0.073 0.2366
Plasmodium falciparum serine repeat antigen 8 0.0344 0.0698 0.2261
Giardia lamblia Cathepsin B precursor 0.0344 0.0698 0.2599
Trypanosoma brucei small myristoylated protein 1-1 0.0384 0.0786 0.2119
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0008
Brugia malayi jmjC domain containing protein 0.0706 0.1496 0.2104
Brugia malayi Calcitonin receptor-like protein seb-1 0.0752 0.1598 0.2248
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0003 0.0001
Brugia malayi RNA binding protein 0.0348 0.0708 0.0994
Echinococcus granulosus fmrfamide receptor 0.0055 0.0061 0.0083
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0537 0.1124 0.3031
Brugia malayi AKH receptor 0.0055 0.0061 0.0083
Giardia lamblia Cathepsin L-like protease 0.0344 0.0698 0.2599
Brugia malayi cathepsin L-like cysteine proteinase 0.0344 0.0698 0.098
Trichomonas vaginalis bromodomain-containing protein, putative 0.0084 0.0124 0.0249
Loa Loa (eye worm) hypothetical protein 0.0051 0.0051 0.007
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0019 0.0033
Schistosoma mansoni jumonji/arid domain-containing protein 0.0279 0.0554 0.0777
Brugia malayi sulfakinin receptor protein 0.0055 0.0061 0.0083
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0344 0.0698 0.2261
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0247 0.0498
Schistosoma mansoni reticulocalbin 0.0089 0.0136 0.0189
Loa Loa (eye worm) aspartyl protease 6 0.0079 0.0114 0.0158
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.005 0.0049 0.0047
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0093 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0426 0.0878 0.1234
Entamoeba histolytica cysteine proteinase, putative 0.0788 0.1678 0.5445
Echinococcus multilocularis cathepsin L cysteine protease 0.1424 0.308 0.3078
Entamoeba histolytica hypothetical protein, conserved 0.0092 0.0142 0.0455
Echinococcus granulosus centrin 2 0.0089 0.0136 0.0189
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0066 0.009
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0673 0.1424 0.3841
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.043 0.0603
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0089 0.0136 0.0189
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0752 0.1598 0.2248
Trypanosoma cruzi caltractin, putative 0.0089 0.0136 0.0189
Schistosoma mansoni opsin-like receptor 0.0055 0.0061 0.0083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0902 0.1929 0.2713
Echinococcus multilocularis tumor protein p63 0.1004 0.2153 0.2151
Loa Loa (eye worm) hypothetical protein 0.1424 0.308 0.4334
Echinococcus granulosus sex peptide receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0149 0.0269 0.0542
Brugia malayi Associated with TFs and helicases family protein 0.0041 0.0029 0.0038
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0238 0.0464 0.0651
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0029 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0537 0.1124 0.158
Echinococcus multilocularis cysteine protease 0.1424 0.308 0.3078
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0315 0.0633 0.1282
Trypanosoma brucei ISWI complex protein 0.0126 0.0217 0.0581
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.0029
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.0061 0.0059
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0771 0.1639 0.2305
Mycobacterium tuberculosis Conserved protein 0.0079 0.0113 0.1076
Brugia malayi calpain 7 0.0673 0.1424 0.2003
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0344 0.0698 0.098
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3248 0.7102 1
Plasmodium vivax plasmepsin IV, putative 0.0335 0.0678 0.2198
Echinococcus granulosus cathepsin L cysteine proteinase 0.1424 0.308 0.4334
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0047 0.0091
Mycobacterium ulcerans glutaminase 0.0187 0.0353 0.5419
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0059 0.0068 0.0093
Brugia malayi cathepsin F-like cysteine proteinase 0.0444 0.0919 0.1292
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.0061 0.0083
Echinococcus multilocularis chromobox protein 2 0.0041 0.0029 0.0027
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0344 0.0698 0.2261
Trichomonas vaginalis calmodulin-2, putative 0.0089 0.0136 0.0273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0029 0.0055
Trypanosoma brucei PAB1-binding protein , putative 0.0111 0.0184 0.0491
Echinococcus multilocularis calmodulin 0.0089 0.0136 0.0134
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.0061 0.0083
Treponema pallidum NADH oxidase 0.0034 0.0014 0.1843
Onchocerca volvulus 0.0326 0.0658 0.1333
Plasmodium vivax calpain, putative 0.0673 0.1424 0.462
Schistosoma mansoni hypothetical protein 0.0034 0.0014 0.0016
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0089 0.0136 0.0273
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Leishmania major programmed cell death 6 protein-like protein 0.0089 0.0136 0.0362
Schistosoma mansoni centrin-related 0.0089 0.0136 0.0189
Echinococcus granulosus jumonji domain containing protein 0.03 0.0601 0.0843
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0344 0.0698 0.2261
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0149 0.0269 0.0542
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0386 0.0791 0.1111
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0104 0.0169 0.0339
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0033 0.0044
Schistosoma mansoni cathepsin F (C01 family) 0.1424 0.308 0.4334
Loa Loa (eye worm) hypothetical protein 0.0322 0.0649 0.0911
Trypanosoma cruzi ISWI complex protein 0.0126 0.0217 0.0303
Brugia malayi beta-lactamase family protein 0.0079 0.0113 0.0157
Leishmania major receptor-type adenylate cyclase a-like protein 0.0223 0.043 0.1157
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Giardia lamblia Cathepsin B precursor 0.1242 0.2678 1
Trypanosoma brucei caltractin, putative 0.0098 0.0155 0.0414
Trypanosoma cruzi cysteine peptidase, putative 0.1729 0.3753 0.5283
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0033 0.0044
Leishmania major 4-coumarate:coa ligase-like protein 0.0039 0.0025 0.0063
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0771 0.1639 0.2305
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0344 0.0698 0.098
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0047 0.0091
Echinococcus multilocularis proteasome (prosome, macropain) 0.0071 0.0097 0.0095
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0058 0.0066 0.0091
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.0061 0.0083
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0061 0.0083
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0061 0.0083
Brugia malayi PHD-finger family protein 0.0216 0.0414 0.0581
Schistosoma mansoni hypothetical protein 0.004 0.0028 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0033 0.0044
Leishmania major hypothetical protein, conserved 0.007 0.0093 0.0245
Brugia malayi hypothetical protein 0.0058 0.0066 0.0091
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0673 0.1424 0.2003
Giardia lamblia Cathepsin L precursor 0.0344 0.0698 0.2599
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0029 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0343 0.0696 0.0977
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3248 0.7102 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0079 0.0114 0.0158
Trichomonas vaginalis calmodulin, putative 0.0098 0.0155 0.0312
Trypanosoma brucei calpain-like protein, putative 0.0673 0.1424 0.3841
Onchocerca volvulus 0.0322 0.0649 0.1314
Toxoplasma gondii kringle domain-containing protein 0.0062 0.0075 0.0238
Echinococcus multilocularis cathepsin L 0.0344 0.0698 0.0696
Loa Loa (eye worm) hypothetical protein 0.0344 0.0698 0.098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0063 0.0124
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0089 0.0136 0.0436
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0082 0.0119 0.0165
Entamoeba histolytica acyl-CoA synthetase, putative 0.0039 0.0025 0.0076
Entamoeba histolytica calcium-binding protein, putative 0.0089 0.0136 0.0436
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.007 0.0094 0.025
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 0.0987
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Echinococcus multilocularis peregrin 0.024 0.0469 0.0467
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0071 0.0097 0.0308
Loa Loa (eye worm) inositol-1 0.0036 0.0018 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0025 0.0033
Schistosoma mansoni hypothetical protein 0.0126 0.0217 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0113 0.0226
Echinococcus multilocularis calumenin 0.0092 0.0142 0.014
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0238 0.0464 0.0651
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0018 0.0245
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0093 0.0128
Echinococcus multilocularis g protein coupled receptor 0.0055 0.0061 0.0059
Schistosoma mansoni hypothetical protein 0.0058 0.0066 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0079 0.0113 0.0157
Schistosoma mansoni reticulocalbin 0.0092 0.0142 0.0197
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.0061 0.0083
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0061 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0033 0.0044
Schistosoma mansoni cpg binding protein 0.0053 0.0056 0.0077
Echinococcus multilocularis Mastin 0.0058 0.0066 0.0065
Onchocerca volvulus 0.0058 0.0066 0.013
Trypanosoma cruzi calmodulin, putative 0.0089 0.0136 0.0189
Loa Loa (eye worm) EF hand family protein 0.0089 0.0136 0.0189
Echinococcus granulosus calpain 0.0673 0.1424 0.2003
Leishmania major META domain containing protein 0.0223 0.043 0.1157
Loa Loa (eye worm) hypothetical protein 0.0079 0.0113 0.0157
Echinococcus granulosus neurocalcin 0.0089 0.0136 0.0189
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1424 0.308 0.4334
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0657 0.1389 0.3748
Onchocerca volvulus 0.0029 0.0003 0.0001
Onchocerca volvulus Alhambra homolog 0.0216 0.0414 0.0837
Brugia malayi F/Y-rich N-terminus family protein 0.0107 0.0176 0.0245
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0359 0.073 0.1026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0002
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0043
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0039 0.0025 0.0084
Onchocerca volvulus 0.0092 0.0142 0.0283
Trypanosoma cruzi kinesin, putative 0.0359 0.073 0.1026
Loa Loa (eye worm) helicase 0.0041 0.0029 0.0038
Giardia lamblia Cathepsin B precursor 0.0344 0.0698 0.2599
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0344 0.0698 0.1414
Trichomonas vaginalis hypothetical protein 0.0041 0.0029 0.0055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0061 0.0059
Echinococcus granulosus Chromobox protein 3 0.0041 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Echinococcus multilocularis lamin 0.0029 0.0003 0.0001
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.0061 0.0083
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0014 0.0032
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0014 0.0038
Schistosoma mansoni hypothetical protein 0.017 0.0314 0.0439
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Schistosoma mansoni sex comb on midleg homolog 0.0144 0.0256 0.0358
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.0061 0.0059
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0037 0.0072
Brugia malayi RE15519p 0.0055 0.0061 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0792 0.1686 0.4548
Loa Loa (eye worm) animal heme peroxidase 0.0114 0.0192 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0247 0.0498
Schistosoma mansoni myosin xvIII 0.0055 0.0061 0.0083
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0089 0.0136 0.0362
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Brugia malayi jmjC domain containing protein 0.0279 0.0554 0.0777
Trichomonas vaginalis myosin light chain 1, putative 0.0089 0.0136 0.0273
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0518 0.1082 0.2917
Leishmania major hypothetical protein, conserved 0.0361 0.0735 0.198
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0444 0.0919 0.1292
Plasmodium falciparum serine repeat antigen 1 0.0344 0.0698 0.2261
Echinococcus granulosus somatostatin receptor 0.0055 0.0061 0.0083
Leishmania major calmodulin, putative 0.0089 0.0136 0.0362
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0344 0.0698 0.098
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0033 0.0044
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0144 0.0256 0.0515
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.006 0.0071 0.0098
Leishmania major cathepsin L-like protease 0.1424 0.308 0.8314
Loa Loa (eye worm) hypothetical protein 0.0444 0.0919 0.1292
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Schistosoma mansoni cpg binding protein 0.0035 0.0017 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0788 0.1678 0.236
Trichomonas vaginalis esterase, putative 0.0079 0.0113 0.0226
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.0061 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0518 0.1082 0.2917
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0114 0.019 0.0265
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0019 0.0035
Entamoeba histolytica acyl-coA synthetase, putative 0.0039 0.0025 0.0076
Echinococcus granulosus peroxidasin 0.0114 0.0192 0.0267
Loa Loa (eye worm) hypothetical protein 0.0079 0.0113 0.0157
Plasmodium vivax plasmepsin V, putative 0.0079 0.0114 0.0364
Giardia lamblia Hypothetical protein 0.0092 0.0142 0.0523
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis peptidase Clp (S14 family) 0.0038 0.0022 0.002
Brugia malayi jmjC domain containing protein 0.007 0.0093 0.0128
Brugia malayi Animal haem peroxidase family protein 0.0114 0.0192 0.0267
Echinococcus granulosus neuropeptide s receptor 0.0352 0.0716 0.1006
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi cathepsin L-like precursor 0.098 0.21 0.2954
Entamoeba histolytica cysteine proteinase, putative 0.1424 0.308 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0203 0.0387 0.0542
Entamoeba histolytica grainin, putative 0.0092 0.0142 0.0455
Schistosoma mansoni hypothetical protein 0.005 0.0049 0.0066
Onchocerca volvulus 0.0058 0.0066 0.013
Echinococcus granulosus tripartite motif containing protein 3 0.0038 0.0023 0.0029
Schistosoma mansoni chromobox protein 0.0041 0.0029 0.0038
Schistosoma mansoni hypothetical protein 0.0177 0.0329 0.0461
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0089 0.0136 0.0362
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.0061 0.0083
Echinococcus granulosus g-protein coupled receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0089 0.0136 0.0273
Giardia lamblia Hypothetical protein 0.0061 0.0074 0.0269
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1424 0.308 1
Onchocerca volvulus 0.0055 0.0061 0.0118
Onchocerca volvulus Huntingtin homolog 0.0077 0.0108 0.0215
Loa Loa (eye worm) hypothetical protein 0.007 0.0093 0.0128
Brugia malayi calpain family protein 1 0.1422 0.3076 0.4329
Brugia malayi calpain D 0.0315 0.0633 0.0888
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0426 0.0878 0.1234
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0248 0.0485 0.4617
Toxoplasma gondii thioredoxin reductase 0.0098 0.0154 0.0496
Onchocerca volvulus 0.0344 0.0698 0.1413
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0788 0.1678 0.3407
Brugia malayi Papain family cysteine protease containing protein 0.0344 0.0698 0.098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0149 0.0269 0.0376
Brugia malayi Serotonin receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis serotonin receptor 0.0055 0.0061 0.0059
Brugia malayi Animal haem peroxidase family protein 0.0114 0.0192 0.0267
Trypanosoma brucei kinesin, putative 0.0359 0.073 0.1967
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Entamoeba histolytica hypothetical protein 0.0164 0.0301 0.0973
Leishmania major prefoldin subunit, putative 0.0061 0.0074 0.0195
Echinococcus multilocularis Chromobox protein 3 0.0041 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0094 0.0187
Toxoplasma gondii cathepsin CPC2 0.0344 0.0698 0.2261
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0017 0.0022
Brugia malayi Cathepsin L-like precursor 0.1424 0.308 0.4334
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Trichomonas vaginalis centrin, putative 0.0089 0.0136 0.0273
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0344 0.0698 0.098
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0014 0.1843
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0041 0.0029 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Schistosoma mansoni inositol monophosphatase 0.0036 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.0029
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0164 0.0301 0.0422
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0033 0.0044
Onchocerca volvulus 0.0055 0.0061 0.0118
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0792 0.1686 0.4548
Loa Loa (eye worm) calpain family protein 1 0.1422 0.3076 0.4329
Plasmodium vivax unspecified product 0.0344 0.0698 0.2261
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Chlamydia trachomatis pyruvate kinase 0.0036 0.0019 0.2519
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0277 0.0549 0.0771
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.0061 0.0083
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 0.0987
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0029 0.0055
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis neuropeptide s receptor 0.0352 0.0716 0.0714
Giardia lamblia Pyruvate kinase 0.0036 0.0019 0.0064
Echinococcus granulosus dna polymerase eta 0.0048 0.0046 0.0062
Trichomonas vaginalis calpain, putative 0.0315 0.0633 0.1282
Loa Loa (eye worm) fibroinase 0.1424 0.308 0.4334
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0082 0.0119 0.0316
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.0061 0.0083
Entamoeba histolytica cysteine protease, putative 0.0344 0.0698 0.2261
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0029 0.0002 0.0019
Brugia malayi Papain family cysteine protease containing protein 0.1424 0.308 0.4334
Toxoplasma gondii hypothetical protein 0.0069 0.0091 0.0289
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0673 0.1424 0.2003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0041 0.0029 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0136 0.0273
Onchocerca volvulus 0.1424 0.308 0.6256
Schistosoma mansoni neuropeptide receptor 0.0055 0.0061 0.0083
Schistosoma mansoni DNA polymerase eta 0.0048 0.0046 0.0062
Brugia malayi PHD-finger family protein 0.0213 0.0408 0.0572
Plasmodium falciparum plasmepsin VI 0.0335 0.0678 0.2198
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0014 0.0182
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0344 0.0698 0.2261
Loa Loa (eye worm) hypothetical protein 0.0426 0.0878 0.1234
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Brugia malayi hypothetical protein 0.004 0.0028 0.0037
Leishmania major trypanothione reductase 0.0098 0.0154 0.0412
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0344 0.0698 0.098
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0344 0.0698 0.2261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Onchocerca volvulus 0.0055 0.0061 0.0118
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.0061 0.0059
Entamoeba histolytica cysteine proteinase, putative 0.0788 0.1678 0.5445
Echinococcus multilocularis tissue type plasminogen activator 0.0062 0.0075 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0285 0.0568 0.0798
Loa Loa (eye worm) glutaminase 0.0187 0.0353 0.0494
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0504 0.1051 1
Schistosoma mansoni alpha-glucosidase 0.0099 0.0157 0.0218
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.2467 0.5379 0.7573
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0344 0.0698 0.2261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Loa Loa (eye worm) animal heme peroxidase 0.0114 0.0192 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS17 0.0038 0.0023 0.0216
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1511 0.3273 0.4606
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0344 0.0698 0.1414
Leishmania major proteasome beta 5 subunit, putative 0.0071 0.0097 0.0256
Echinococcus granulosus PHD finger protein rhinoceros 0.0216 0.0414 0.0581
Plasmodium falciparum glutathione reductase 0.0098 0.0154 0.0496
Entamoeba histolytica hypothetical protein 0.0164 0.0301 0.0973
Brugia malayi Trypsin family protein 0.0058 0.0066 0.0091
Loa Loa (eye worm) cathepsin B 0.1242 0.2678 0.377
Trypanosoma cruzi conserved protein 0.0547 0.1145 0.161
Mycobacterium ulcerans beta-lactamase 0.0079 0.0113 0.1718
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0279 0.0554 0.0777
Trypanosoma brucei cysteine peptidase, putative 0.0537 0.1124 0.3031
Echinococcus multilocularis cathepsin L 0.0788 0.1678 0.1676
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Loa Loa (eye worm) hypothetical protein 0.0344 0.0698 0.098
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Echinococcus multilocularis jumonji domain containing protein 0.03 0.0601 0.0599
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0673 0.1423 0.3839
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.0322 0.0649 0.0911
Echinococcus granulosus thioredoxin glutathione reductase 0.0098 0.0154 0.0215
Echinococcus granulosus g protein coupled receptor 0.0055 0.0061 0.0083
Toxoplasma gondii hypothetical protein 0.0315 0.0633 0.205
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0203 0.0387 0.0385
Schistosoma mansoni dopamine-beta-monooxygenase 0.0771 0.1639 0.2305
Brugia malayi mbt repeat family protein 0.0144 0.0256 0.0358
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0588 0.1235 0.1736
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.0033
Brugia malayi hypothetical protein 0.0079 0.0114 0.0158
Brugia malayi acetyltransferase, GNAT family protein 0.0239 0.0466 0.0654
Onchocerca volvulus 0.0066 0.0085 0.0168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0047 0.0091
Brugia malayi Cathepsin L-like precursor 0.098 0.21 0.2954
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0113 0.2283
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.037 0.0754 0.1059
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0528 0.107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Entamoeba histolytica grainin 2 0.0098 0.0155 0.0498
Echinococcus granulosus peregrin 0.024 0.0469 0.0658
Echinococcus granulosus cysteine protease 0.0788 0.1678 0.236
Schistosoma mansoni calmodulin 0.0089 0.0136 0.0189
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis calmodulin, putative 0.0092 0.0142 0.0285
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0003 0.0002
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0044 0.0036 0.0048
Brugia malayi nuclear hormone receptor 0.0043 0.0033 0.0044
Brugia malayi Cathepsin L-like precursor 0.1424 0.308 0.4334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis pyruvate kinase 0.0036 0.0019 0.0017
Onchocerca volvulus 0.0114 0.0192 0.0384
Brugia malayi Trypsin-like protease protein 5 0.0058 0.0066 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0049 0.0096
Brugia malayi SET domain containing protein 0.0029 0.0003 0.0002
Schistosoma mansoni calpain C (C02 family) 0.0673 0.1424 0.2003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Leishmania major hypothetical protein, conserved 0.0223 0.043 0.1157
Schistosoma mansoni brat protein 0.0038 0.0023 0.0029
Loa Loa (eye worm) hypothetical protein 0.014 0.0247 0.0345
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0071 0.0097 0.0354
Brugia malayi cathepsin L precursor 0.0344 0.0698 0.098
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0071 0.0097 0.0133
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1424 0.308 0.3078
Echinococcus granulosus lysosomal alpha glucosidase 0.0115 0.0192 0.0268
Loa Loa (eye worm) RNA binding protein 0.0348 0.0708 0.0994
Brugia malayi Matrixin family protein 0.0058 0.0066 0.009
Trichomonas vaginalis hypothetical protein 0.0315 0.0633 0.1282
Giardia lamblia Cysteine protease 0.0344 0.0698 0.2599
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0518 0.1082 0.1521
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0335 0.0678 0.0953
Schistosoma mansoni neuronal calcium sensor 0.0089 0.0136 0.0189
Onchocerca volvulus 0.0144 0.0256 0.0515
Plasmodium falciparum plasmepsin II 0.0335 0.0678 0.2198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0084 0.0167
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Echinococcus granulosus neuropeptide receptor A26 0.0352 0.0716 0.1006
Loa Loa (eye worm) hypothetical protein 0.0583 0.1224 0.1721
Trypanosoma brucei hypothetical protein, conserved 0.0089 0.0136 0.0362
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0335 0.0678 0.1375
Entamoeba histolytica cysteine proteinase, putative 0.0788 0.1678 0.5445
Echinococcus multilocularis hypothetical protein 0.0673 0.1424 0.1422
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0036 0.0019 0.0047
Onchocerca volvulus 0.0041 0.0029 0.0053
Schistosoma mansoni lamin 0.0029 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Trypanosoma cruzi unspecified product 0.0384 0.0786 0.1105
Plasmodium vivax unspecified product 0.0444 0.0919 0.298
Leishmania major centrin, putative 0.0089 0.0136 0.0362
Schistosoma mansoni calpain-7 (C02 family) 0.0679 0.1438 0.2022
Trypanosoma cruzi centrin-3 0.0098 0.0155 0.0216
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0033 0.0031
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0706 0.1496 0.2104
Loa Loa (eye worm) hypothetical protein 0.007 0.0093 0.0128
Trypanosoma brucei Calpain-like protein 1.1 0.0902 0.1929 0.5205
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0348 0.0708 0.0994
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0003 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0033 0.0062
Brugia malayi cathepsin F-like cysteine proteinase 0.0344 0.0698 0.098
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0008
Plasmodium vivax aspartyl proteinase, putative 0.0335 0.0678 0.2198
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0019 0.0024
Schistosoma mansoni hypothetical protein 0.0216 0.0414 0.0581
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.0061 0.0059
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0149 0.0269 0.0376
Schistosoma mansoni rab 0.0089 0.0136 0.0189
Toxoplasma gondii EF hand domain-containing protein 0.0089 0.0136 0.0436
Schistosoma mansoni survival motor neuron protein 0.0067 0.0086 0.0118
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Trypanosoma brucei centrin, putative 0.0089 0.0136 0.0362
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.1451 0.3139 0.4418
Trypanosoma brucei prefoldin subunit, putative 0.0061 0.0074 0.0195
Brugia malayi Glycosyl hydrolases family 31 protein 0.0115 0.0192 0.0268
Leishmania major protein kinase, putative 0.0089 0.0136 0.0362
Brugia malayi B-box zinc finger family protein 0.0038 0.0023 0.0029
Schistosoma mansoni chromobox protein 0.0041 0.0029 0.0038
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.0061 0.0059
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0113 0.0226
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0033 0.0044
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0003 0.0003
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.007 0.0094 0.0301
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0113 0.1076
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0082 0.0119 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.0698 0.1414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0119 0.0238
Brugia malayi Bromodomain containing protein 0.024 0.0469 0.0658
Loa Loa (eye worm) hypothetical protein 0.0077 0.0108 0.015
Loa Loa (eye worm) TAR-binding protein 0.0348 0.0708 0.0994
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0203 0.0387 0.0542
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0144 0.0256 0.0358
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Giardia lamblia Cathepsin B precursor 0.0344 0.0698 0.2599
Echinococcus multilocularis serotonin receptor 0.0055 0.0061 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0113 0.0157
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0014 0.0024
Onchocerca volvulus 0.2259 0.4921 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0788 0.1678 0.5445
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0223 0.043 0.1157
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0019 0.0024
Trypanosoma brucei calpain-like protein, putative 0.0673 0.1424 0.3841
Loa Loa (eye worm) hypothetical protein 0.0326 0.0659 0.0925
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.007 0.0093 0.0294
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.0061 0.0083
Echinococcus granulosus Chromo domain 0.0041 0.0029 0.0038
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.1451 0.3139 0.4418
Brugia malayi Probable ClpP-like protease 0.0057 0.0066 0.009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0049 0.0047 0.0091
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0285 0.0568 0.0567
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0018 0.0022
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0877 0.1873 0.2635
Schistosoma mansoni calmodulin related calcium binding protein 0.0089 0.0136 0.0189
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0113 0.0226
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0041 0.0029 0.0038
Mycobacterium ulcerans hypothetical protein 0.0039 0.0025 0.0361
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0019 0.0047
Echinococcus granulosus prefoldin subunit 6 0.0061 0.0074 0.0101
Echinococcus multilocularis chromobox protein 1 0.0249 0.0489 0.0487
Plasmodium vivax serine-repeat antigen (SERA) 0.0344 0.0698 0.2261
Toxoplasma gondii centrin, putative 0.0089 0.0136 0.0436
Entamoeba histolytica hypothetical protein 0.012 0.0204 0.0655
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi jmjC domain containing protein 0.007 0.0093 0.0128
Leishmania major small myristoylated protein-2 0.07 0.1483 0.4001
Onchocerca volvulus 0.1424 0.308 0.6256
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0386 0.0791 0.1111
Trypanosoma cruzi centrin, putative 0.0098 0.0155 0.0216
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0325 0.0657 0.0922
Echinococcus multilocularis muscleblind protein 1 0.0114 0.019 0.0188
Echinococcus granulosus calcium uptake protein 1 0.0092 0.0142 0.0197
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.0061 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0956 0.2047 0.5523
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0113 0.0226
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.005 0.0049 0.0066
Schistosoma mansoni hypothetical protein 0.0238 0.0464 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0024
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.0061 0.0083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0902 0.1929 0.2713
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0788 0.1678 0.3407
Brugia malayi mbt repeat family protein 0.0144 0.0256 0.0358
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0039 0.0025 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0033 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0041 0.0078
Brugia malayi calcium-binding protein 0.0089 0.0136 0.0189
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0029 0.0088
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0033 0.0044
Trypanosoma brucei flagellum-adhesion glycoprotein, putative 0.0038 0.0023 0.0056
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1242 0.2678 0.377
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Leishmania major hypothetical protein, conserved 0.0079 0.0113 0.03
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0014 0.0038
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0956 0.2047 0.5523
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0282 0.0562 0.1512
Brugia malayi TspO/MBR family protein 0.0322 0.0649 0.0911
Brugia malayi follicle stimulating hormone receptor 0.0204 0.0388 0.0544
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0047 0.0091
Schistosoma mansoni hypothetical protein 0.0514 0.1073 0.1509
Loa Loa (eye worm) calmodulin-like protein 0.0089 0.0136 0.0189
Echinococcus granulosus brain tumor protein 0.0038 0.0023 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.004 0.0078
Schistosoma mansoni intermediate filament proteins 0.0029 0.0003 0.0002
Schistosoma mansoni neuropeptide receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis thyroid hormone receptor alpha 0.022 0.0423 0.0421
Brugia malayi Cathepsin L-like precursor 0.1424 0.308 0.4334
Onchocerca volvulus Glucosylceramidase homolog 0.0253 0.0498 0.1007
Plasmodium vivax proteasome subunit beta type-5, putative 0.0071 0.0097 0.0308
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trypanosoma brucei protein I/6 0.0089 0.0136 0.0362
Onchocerca volvulus Huntingtin homolog 0.0077 0.0108 0.0215
Brugia malayi hypothetical protein 0.0164 0.0301 0.0422
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0017
Leishmania major small myristoylated protein-1 0.0384 0.0786 0.2119
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0066 0.0129
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0282 0.0562 0.1512
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0055
Entamoeba histolytica prefoldin subunit 6, putative 0.0061 0.0074 0.0234
Loa Loa (eye worm) acetyltransferase 0.0239 0.0466 0.0654
Schistosoma mansoni ef hand domain family member A2 0.0089 0.0136 0.0189
Echinococcus multilocularis polycomb protein SCMH1 0.0144 0.0256 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0344 0.0698 0.1414
Toxoplasma gondii microneme protein MIC4 0.0029 0.0003 0.0003
Plasmodium falciparum thioredoxin reductase 0.0034 0.0014 0.0038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0014 0.0182
Leishmania major hypothetical protein, conserved 0.0223 0.043 0.1157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0326 0.0658 0.0924
Schistosoma mansoni hypothetical protein 0.0089 0.0136 0.0189
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.007 0.0093 0.0245
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0033 0.0044
Trypanosoma brucei Component of motile flagella 41 0.0089 0.0136 0.0362
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0956 0.2047 0.2879
Mycobacterium tuberculosis Probable reductase 0.0223 0.043 0.4095
Mycobacterium ulcerans proteasome PrcB 0.0071 0.0097 0.1463
Brugia malayi calpain family protein 1 0.1422 0.3076 0.4329
Schistosoma mansoni hypothetical protein 0.0038 0.0023 0.0029
Echinococcus granulosus glycoprotein Antigen 5 0.0058 0.0066 0.0091
Trypanosoma brucei mitochondrial calcium uptake 1 0.0089 0.0136 0.0362
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0066 0.0084 0.0222
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0157 0.0316
Plasmodium falciparum pyruvate kinase 0.0036 0.0019 0.0056
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0071 0.0097 0.0133
Schistosoma mansoni glutaminase 0.0187 0.0353 0.0494
Onchocerca volvulus 0.0749 0.1591 0.3229
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0788 0.1678 0.236
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0038
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0315 0.0633 0.1282
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0014 0.0131
Schistosoma mansoni biogenic amine receptor 0.0055 0.0061 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0855 0.1826 0.4927
Schistosoma mansoni hypothetical protein 0.088 0.1879 0.2644
Plasmodium vivax centrin-1, putative 0.0089 0.0136 0.0436
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0673 0.1424 0.2003
Trypanosoma cruzi major cysteine proteinase, putative 0.0627 0.1322 0.1859
Loa Loa (eye worm) mbt repeat family protein 0.0144 0.0256 0.0358
Leishmania major kinesin, putative 0.0359 0.073 0.1967
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0041 0.0029 0.0038
Echinococcus granulosus neuronal calcium sensor 0.0089 0.0136 0.0189
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0285 0.0568 0.1841
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0032
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0029 0.0088
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0092 0.0142 0.0197
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0149 0.0269 0.0867
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0046 0.0062
Brugia malayi jmjC domain containing protein 0.007 0.0093 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Brugia malayi PHD-finger family protein 0.0088 0.0134 0.0185
Loa Loa (eye worm) hypothetical protein 0.3248 0.7102 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.0061 0.0059
Trypanosoma cruzi cysteine proteinase, putative 0.0788 0.1678 0.236
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni inositol monophosphatase 0.0036 0.0018 0.0022
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.1451 0.3139 0.3137
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0003 0.0003
Trichomonas vaginalis calcium binding protein, putative 0.0098 0.0155 0.0312
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0344 0.0698 0.1414
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi Protein kinase domain containing protein 0.0062 0.0075 0.0103
Plasmodium falciparum proteasome subunit beta type-5 0.0071 0.0097 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0075 0.0149
Plasmodium falciparum phd finger protein, putative 0.0216 0.0414 0.134
Brugia malayi Trypsin family protein 0.0058 0.0066 0.0091
Onchocerca volvulus 0.0055 0.0061 0.0118
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis glutaminase, putative 0.0187 0.0353 0.0713
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Toxoplasma gondii PHD-finger domain-containing protein 0.0216 0.0414 0.134
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.1108 0.2382 0.3352
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0033 0.0044
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0003 0.0001
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0041 0.0029 0.0073
Brugia malayi putative neuropeptide receptor 0.0055 0.0061 0.0083
Schistosoma mansoni microtubule-associated protein tau 0.2962 0.6471 0.9111
Onchocerca volvulus 0.0029 0.0003 0.0001
Plasmodium vivax serine-repeat antigen (SERA) 0.0344 0.0698 0.2261
Trypanosoma cruzi I/6 autoantigen, putative 0.0089 0.0136 0.0189
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0203 0.0387 0.0542
Mycobacterium ulcerans hypothetical protein 0.0225 0.0435 0.6692
Brugia malayi ecdysteroid receptor 0.0043 0.0033 0.0044
Trichomonas vaginalis calcineurin B subunit, putative 0.0092 0.0142 0.0285
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0315 0.0633 0.1282
Loa Loa (eye worm) hypothetical protein 0.098 0.21 0.2954
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Leishmania major calmodulin-like protein 0.0089 0.0136 0.0362
Mycobacterium tuberculosis Probable dehydrogenase 0.0223 0.043 0.4095
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0223 0.043 0.4095
Schistosoma mansoni coup transcription factor 0.0043 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.007 0.0093 0.0128
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0029 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Giardia lamblia Cysteine protease 0.0344 0.0698 0.2599
Echinococcus granulosus fetal alzheimer antigen falz 0.0188 0.0353 0.0495
Loa Loa (eye worm) transcription factor SMAD2 0.0254 0.0499 0.07
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0022
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0537 0.1124 0.158
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0325 0.0657 0.0922
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Echinococcus granulosus calumenin 0.0092 0.0142 0.0197
Brugia malayi EF hand family protein 0.0089 0.0136 0.0189
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0223 0.043 0.1157
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0033 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0033 0.0044
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0061 0.0059
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis cathepsin b 0.3248 0.7102 0.7102
Schistosoma mansoni phosphatidylserine receptor 0.007 0.0093 0.0128
Echinococcus granulosus cathepsin L cysteine protease 0.0788 0.1678 0.236
Brugia malayi Cathepsin L-like precursor 0.098 0.21 0.2954
Onchocerca volvulus Cathepsin L homolog 0.1424 0.308 0.6256
Onchocerca volvulus Peroxidase homolog 0.0114 0.0192 0.0384
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0344 0.0698 0.2261
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0119 0.0238
Leishmania major hypothetical protein, unknown function 0.0315 0.0633 0.1704
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0113 0.0361
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Onchocerca volvulus Chorion peroxidase homolog 0.0114 0.0192 0.0384
Brugia malayi hypothetical protein 0.0079 0.0114 0.0158
Leishmania major cathepsin L-like protease 0.1707 0.3704 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.0061 0.0083
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0038 0.0022 0.0211
Trypanosoma cruzi small myristoylated protein 1-2 0.0384 0.0786 0.1105
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Plasmodium falciparum plasmepsin X 0.0079 0.0114 0.0364
Schistosoma mansoni hypothetical protein 0.0067 0.0086 0.0118
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0062 0.0075 0.0238
Echinococcus multilocularis fmrfamide receptor 0.0055 0.0061 0.0059
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0427 0.088 0.2373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.098 0.21 0.4264
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0019 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0344 0.0698 0.1414
Echinococcus granulosus cathepsin L 0.0344 0.0698 0.098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0203 0.0387 0.0542
Schistosoma mansoni hypothetical protein 0.0238 0.0464 0.0651
Entamoeba histolytica hypothetical protein 0.0041 0.0029 0.0088
Schistosoma mansoni cathepsin s 0.0444 0.0919 0.1292
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0223 0.043 0.1157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis cysteine protease 0.1424 0.308 0.3078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0033 0.0044
Toxoplasma gondii hypothetical protein 0.0029 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0089 0.0136 0.0362
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0089 0.0136 0.0189
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Schistosoma mansoni peptidase Clp (S14 family) 0.0057 0.0066 0.009
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis set domain proteins, putative 0.2259 0.4921 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Plasmodium vivax prefoldin subunit 6, putative 0.0061 0.0074 0.0234
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Schistosoma mansoni adenoreceptor 0.0055 0.0061 0.0083
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Plasmodium vivax vivapain-3 0.0788 0.1678 0.5445
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Echinococcus multilocularis tripartite motif containing protein 3 0.0038 0.0023 0.0021
Brugia malayi RNA recognition motif domain containing protein 0.0348 0.0708 0.0994
Schistosoma mansoni neuronal calcium sensor 0.0089 0.0136 0.0189
Brugia malayi Blistered cuticle protein 3 0.0114 0.0192 0.0267
Onchocerca volvulus 0.004 0.0028 0.0051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0902 0.1929 0.5205
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0061 0.0083
Plasmodium falciparum centrin-1 0.0089 0.0136 0.0436
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Giardia lamblia Hypothetical protein 0.0038 0.0023 0.0078
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0657 0.1389 0.1954
Echinococcus multilocularis translocator protein 0.0322 0.0649 0.0647
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0089 0.0136 0.0436
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.0061 0.0083
Brugia malayi RNA, U transporter 1 0.0062 0.0076 0.0104
Entamoeba histolytica cysteine protease, putative 0.0344 0.0698 0.2261
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0344 0.0698 0.1414
Toxoplasma gondii preprocathepsin c precursor, putative 0.0344 0.0698 0.2261
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0033 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0033 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.0061 0.0083
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0099 0.0156 0.0218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0788 0.1678 0.236
Trichomonas vaginalis chromobox protein, putative 0.0249 0.0489 0.0989
Schistosoma mansoni biogenic amine receptor 0.0055 0.0061 0.0083
Trypanosoma cruzi cysteine proteinase, putative 0.0788 0.1678 0.236
Toxoplasma gondii cathepsin CPC1 0.0344 0.0698 0.2261
Plasmodium falciparum serine repeat antigen 9 0.0344 0.0698 0.2261
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1263 0.2724 0.3833
Mycobacterium ulcerans hypothetical protein 0.0079 0.0113 0.1718
Giardia lamblia Cysteine protease 0.0344 0.0698 0.2599
Schistosoma mansoni protein phosphatase 2C 0.007 0.0093 0.0128
Schistosoma mansoni amine GPCR 0.0055 0.0061 0.0083
Echinococcus granulosus g protein coupled receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0113 0.0157
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0537 0.1124 0.158
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0537 0.1124 0.3031
Schistosoma mansoni peptidylglycine monooxygenase 0.0771 0.1639 0.2305
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0059 0.0068 0.0066
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0499 0.104 0.1038
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0014 0.0044
Giardia lamblia Encystation-specific protease 0.0344 0.0698 0.2599
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0752 0.1598 0.2248
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0041 0.0029 0.0088
Onchocerca volvulus 0.0147 0.0263 0.0529
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Echinococcus multilocularis brain tumor protein 0.0038 0.0023 0.0021
Echinococcus granulosus calpain 7 C02 family 0.0673 0.1424 0.2003
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.0061 0.0059
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0902 0.1929 0.2713
Schistosoma mansoni lamin 0.0029 0.0003 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0086 0.0128 0.0178
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.0061 0.0059
Echinococcus granulosus calpain A 0.1514 0.3279 0.4615
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.0061 0.0083
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0014 0.0017
Trypanosoma brucei I/6 autoantigen 0.0089 0.0136 0.0362
Leishmania major i/6 autoantigen-like protein 0.0089 0.0136 0.0362
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0082 0.0119 0.0316
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0113 0.03
Loa Loa (eye worm) glutaminase 2 0.0187 0.0353 0.0494
Mycobacterium ulcerans hydrolase 0.0029 0.0003 0.0017
Echinococcus multilocularis SAM and MBT domain containing protein 0.0144 0.0256 0.0254
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.0061 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.0698 0.1414
Toxoplasma gondii LsmAD domain-containing protein 0.0111 0.0184 0.0591
Entamoeba histolytica hypothetical protein 0.0038 0.0023 0.0067
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.0061 0.0118
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0248 0.0485 0.4617
Schistosoma mansoni phd/f-box containing protein 0.007 0.0093 0.0128
Schistosoma mansoni sex comb on midleg homolog 0.0144 0.0256 0.0358
Leishmania major hypothetical protein, conserved 0.0126 0.0217 0.0581
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0082 0.0119 0.0165
Leishmania major DNA polymerase eta, putative 0.0048 0.0046 0.0119
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0053 0.0057 0.0178
Echinococcus multilocularis musashi 0.0029 0.0003 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0014 0.0012
Brugia malayi neuropeptide F receptor 0.0055 0.0061 0.0083
Schistosoma mansoni hypothetical protein 0.007 0.0094 0.013
Schistosoma mansoni hypothetical protein 0.1083 0.2328 0.3277
Onchocerca volvulus 0.0067 0.0086 0.0169
Leishmania major hypothetical protein, conserved 0.0223 0.043 0.1157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0673 0.1424 0.2003
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0282 0.0562 0.1512
Brugia malayi Pre-SET motif family protein 0.0285 0.0568 0.0798
Leishmania major pyruvate kinase 0.0036 0.0019 0.0047
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0003 0.0003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0325 0.0657 0.0922
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.0061 0.0083
Plasmodium falciparum heterochromatin protein 1 0.0041 0.0029 0.0088
Toxoplasma gondii histone lysine demethylase JMJD6a 0.007 0.0093 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0084 0.0167
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0099 0.0316
Loa Loa (eye worm) PHD-finger family protein 0.017 0.0314 0.0439
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0041 0.0029 0.0088
Brugia malayi chromobox protein homolog 3 0.014 0.0247 0.0345
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0061 0.0083
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0041 0.0029 0.0038
Loa Loa (eye worm) hypothetical protein 0.0164 0.03 0.042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0325 0.0657 0.1769
Loa Loa (eye worm) jmjC domain-containing protein 0.0279 0.0554 0.0777
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.0061 0.0083
Brugia malayi hypothetical protein 0.0132 0.0229 0.032
Onchocerca volvulus 0.0114 0.0192 0.0384
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0087 0.0132 0.0183
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Plasmodium falciparum glutathione reductase 0.0034 0.0014 0.0038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.0061 0.0083
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.001 0.0091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0518 0.1082 0.1521
Echinococcus granulosus muscleblind protein 0.0114 0.019 0.0265
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0089 0.0136 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0315 0.0633 0.1704
Schistosoma mansoni Mername-AA248 (C02 family) 0.0673 0.1424 0.2003
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0014 0.0024
Leishmania major mitochondrial DNA polymerase beta 0.0427 0.088 0.2373
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0014 0.0017
Brugia malayi hypothetical protein 0.0114 0.0192 0.0267
Leishmania major hypothetical protein, conserved 0.0547 0.1145 0.3088
Giardia lamblia Cathepsin B precursor 0.0344 0.0698 0.2599
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0029 0.0088
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0518 0.1082 0.2917
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Toxoplasma gondii troponin c, isotype gamma, putative 0.0089 0.0136 0.0436
Loa Loa (eye worm) hypothetical protein 0.0322 0.0649 0.0911
Plasmodium vivax heterochromatin protein 1, putative 0.0041 0.0029 0.0088
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0033 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.043 0.0603
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0537 0.1124 0.158
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0087 0.013 0.0128
Trypanosoma brucei conserved protein 0.0232 0.0451 0.1214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0041 0.0078
Schistosoma mansoni hypothetical protein 0.0055 0.0061 0.0083
Entamoeba histolytica cysteine protease, putative 0.0788 0.1678 0.5445
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0233 0.0453 0.0635
Brugia malayi Bromodomain containing protein 0.0625 0.1318 0.1854
Mycobacterium tuberculosis Conserved hypothetical protein 0.0225 0.0435 0.4138
Leishmania major cathepsin L-like protease 0.1424 0.308 0.8314
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1424 0.308 1
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0003 0.0003
Plasmodium vivax thioredoxin reductase, putative 0.0098 0.0154 0.0496
Onchocerca volvulus 0.0089 0.0136 0.0271
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0113 0.0157
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0335 0.0678 0.0953
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1424 0.308 0.6257
Leishmania major calmodulin-like protein 0.0089 0.0136 0.0362
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0019 0.0024
Toxoplasma gondii hypothetical protein 0.0029 0.0003 0.0003
Giardia lamblia Cathepsin L precursor 0.0344 0.0698 0.2599
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0014 0.0017
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0344 0.0698 0.2261
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.038 0.0776 0.109
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.0061 0.0083
Plasmodium vivax JmjC domain containing protein 0.007 0.0093 0.0294
Loa Loa (eye worm) matrixin family protein 0.0058 0.0066 0.009
Echinococcus multilocularis microtubule associated protein 2 0.2962 0.6471 0.6471
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0071 0.0097 0.194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0033 0.0044
Trichomonas vaginalis calmodulin, putative 0.0089 0.0136 0.0273
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0877 0.1873 0.2635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0344 0.0698 0.1414
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0335 0.0678 0.2198
Onchocerca volvulus Cathepsin L homolog 0.1424 0.308 0.6256
Onchocerca volvulus Cathepsin L homolog 0.0344 0.0698 0.1413
Echinococcus multilocularis calpain A 0.1514 0.3279 0.3277
Entamoeba histolytica hypothetical protein 0.0344 0.0698 0.2261
Brugia malayi cathepsin B-like cysteine proteinase 0.3248 0.7102 1
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0071 0.0097 0.0919
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0113 0.1076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0099 0.0156 0.0218
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0046 0.0119
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0344 0.0698 0.2261
Leishmania major hypothetical protein, conserved 0.0092 0.0142 0.0378
Echinococcus multilocularis dna polymerase eta 0.0048 0.0046 0.0044
Onchocerca volvulus 0.0039 0.0025 0.0046
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0018 0.0051
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0049 0.0047 0.0091
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0344 0.0698 0.098
Brugia malayi hypothetical protein 0.0041 0.0029 0.0039
Echinococcus granulosus pyruvate kinase 0.0036 0.0019 0.0024
Onchocerca volvulus 0.0043 0.0033 0.0062
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Brugia malayi B-box type zinc-finger protein ncl-1 0.0038 0.0023 0.0029
Mycobacterium ulcerans lipase LipD 0.0079 0.0113 0.1718
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0093 0.0128
Loa Loa (eye worm) bromodomain containing protein 0.0151 0.0272 0.038
Loa Loa (eye worm) ctsf protein 0.1424 0.308 0.4334
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0956 0.2047 0.2879
Loa Loa (eye worm) latrophilin receptor protein 2 0.0238 0.0464 0.0651
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0202 0.0385 0.0539
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.0061 0.0083
Trichomonas vaginalis calpain, putative 0.0315 0.0633 0.1282
Brugia malayi Animal haem peroxidase family protein 0.0114 0.0192 0.0267
Plasmodium vivax ataxin-2 like protein, putative 0.0111 0.0184 0.0591
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0223 0.043 0.1157
Schistosoma mansoni zinc finger protein 0.0126 0.0217 0.0303
Plasmodium vivax aspartyl protease, putative 0.0079 0.0114 0.0364
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.0005
Trypanosoma brucei calpain, putative 0.0315 0.0633 0.1704
Schistosoma mansoni peroxidasin 0.0114 0.0192 0.0267
Loa Loa (eye worm) hypothetical protein 0.1451 0.3139 0.4418
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0058 0.0066 0.0091
Echinococcus multilocularis calpain family protein 1, d 0.1063 0.2285 0.2283
Brugia malayi AMP-binding enzyme family protein 0.0039 0.0025 0.0033
Loa Loa (eye worm) hypothetical protein 0.0749 0.1591 0.2238
Schistosoma mansoni cathepsin F (C01 family) 0.1424 0.308 0.4334
Entamoeba histolytica cysteine protease, putative 0.0344 0.0698 0.2261
Echinococcus granulosus tissue type plasminogen activator 0.0062 0.0075 0.0103
Plasmodium vivax glutathione reductase, putative 0.0098 0.0154 0.0496
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0084 0.0167
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0033 0.0062
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.0061 0.0059
Brugia malayi Serotonin receptor 0.0055 0.0061 0.0083
Trichomonas vaginalis chromobox protein, putative 0.015 0.027 0.0546
Schistosoma mansoni tar DNA-binding protein 0.0348 0.0708 0.0994
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0041 0.0078
Brugia malayi Papain family cysteine protease containing protein 0.0344 0.0698 0.098
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0692 0.1465 0.3954
Echinococcus multilocularis GPCR, family 2 0.0238 0.0464 0.0462
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0164 0.0301 0.03
Echinococcus multilocularis PHD finger protein rhinoceros 0.0216 0.0414 0.0413
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.0061 0.0083
Echinococcus granulosus EF hand domain containing family member A2 0.0089 0.0136 0.0189
Schistosoma mansoni cercarial elastase (S01 family) 0.0058 0.0066 0.0091
Echinococcus multilocularis EF hand domain containing family member A2 0.0092 0.0142 0.014
Schistosoma mansoni thyroid hormone receptor 0.022 0.0423 0.0593
Brugia malayi Dopamine receptor protein 2 0.0055 0.0061 0.0083
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0164 0.03 0.042
Schistosoma mansoni hypothetical protein 0.0056 0.0062 0.0085
Echinococcus multilocularis neurocalcin 0.0089 0.0136 0.0134
Onchocerca volvulus 0.0058 0.0066 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1707 0.3704 1
Schistosoma mansoni hypothetical protein 0.0041 0.0029 0.0038
Toxoplasma gondii ABC1 family protein 0.0079 0.0113 0.0361
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.0698 0.1414
Schistosoma mansoni cathepsin D (A01 family) 0.0988 0.2119 0.2982
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0082 0.0119 0.0165
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0014 0.0017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.045 0.0932 0.131
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0061 0.0059
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.0061 0.0083
Echinococcus granulosus cathepsin l1 0.1424 0.308 0.4334
Plasmodium vivax vivapain-1 0.0788 0.1678 0.5445
Echinococcus multilocularis neuropeptide receptor 0.0055 0.0061 0.0059
Schistosoma mansoni myelin transcription factor 1 myt1 0.0164 0.03 0.042
Loa Loa (eye worm) trypsin family protein 0.0058 0.0066 0.0091
Echinococcus multilocularis lamin dm0 0.0029 0.0003 0.0001
Entamoeba histolytica acetyltransferase, GNAT family 0.0059 0.007 0.022
Onchocerca volvulus 0.0089 0.0136 0.0271
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0119 0.0238
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0053 0.0057 0.0111
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.0061 0.0083
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0038
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0315 0.0633 0.1282
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0003 0.0001
Onchocerca volvulus 0.0055 0.0061 0.0118
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0426 0.0878 0.0876
Echinococcus multilocularis Chromo domain 0.0041 0.0029 0.0027
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0003 0.0003
Toxoplasma gondii subtilisin SUB12 0.0029 0.0003 0.0003
Echinococcus multilocularis JmjC domain containing protein 4 0.007 0.0093 0.0091
Loa Loa (eye worm) hypothetical protein 0.0114 0.0192 0.0267
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0692 0.1465 0.2061
Schistosoma mansoni hypothetical protein 0.1083 0.2328 0.3277
Echinococcus granulosus cpg binding protein 0.0053 0.0056 0.0077
Giardia lamblia Haloacid dehalogenase-like hydrolase family 0.0038 0.0023 0.0078
Brugia malayi Pre-SET motif family protein 0.1985 0.4316 0.6076
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.0061 0.0059
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0344 0.0698 0.2599
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0018 0.2478
Toxoplasma gondii proteasome subunit beta type, putative 0.0071 0.0097 0.0308
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0053 0.0057 0.0077
Schistosoma mansoni neuronal calcium sensor 0.0089 0.0136 0.0189
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni hypothetical protein 0.0038 0.0023 0.0029
Echinococcus multilocularis somatostatin receptor 0.0055 0.0061 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0348 0.0708 0.0994
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0058 0.0066 0.0091
Echinococcus multilocularis pyruvate kinase 0.0036 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Toxoplasma gondii PHD-finger domain-containing protein 0.007 0.0094 0.0301
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0014 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Brugia malayi Dopamine receptor protein 1 0.0055 0.0061 0.0083
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0079 0.0114 0.0158
Plasmodium vivax SET domain containing protein 0.0036 0.0019 0.0055
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0344 0.0698 0.098
Entamoeba histolytica calmodulin, putative 0.0089 0.0136 0.0436
Schistosoma mansoni hypothetical protein 0.0055 0.0061 0.0083
Brugia malayi jmjC domain containing protein 0.007 0.0093 0.0128
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0041 0.0029 0.0088
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0315 0.0633 0.205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1424 0.308 0.6257
Loa Loa (eye worm) hypothetical protein 0.0344 0.0698 0.098
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0058 0.0066 0.0091
Plasmodium vivax vivapain-2 0.1424 0.308 1
Brugia malayi glutaminase DH11.1 0.0187 0.0353 0.0494
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0043 0.0033 0.0044
Brugia malayi programmed cell death protein 6 0.0089 0.0136 0.0189
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0033 0.0044
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0149 0.0269 0.0376
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0018 0.0032
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0057 0.0066 0.0064
Entamoeba histolytica cysteine protease, putative 0.0344 0.0698 0.2261
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.0061 0.0059
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0098 0.0154 0.147
Schistosoma mansoni memapsin-2 (A01 family) 0.0079 0.0114 0.0158
Onchocerca volvulus 0.098 0.21 0.4263
Brugia malayi Heterochromatin protein 1 0.0249 0.0489 0.0685
Loa Loa (eye worm) hypothetical protein 0.0109 0.0181 0.0252
Loa Loa (eye worm) cysteine protease 0.1424 0.308 0.4334
Loa Loa (eye worm) hypothetical protein 0.0057 0.0066 0.009
Brugia malayi Cathepsin L-like precursor 0.1424 0.308 0.4334
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0033 0.0031
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0033 0.0044
Brugia malayi calpain 5 0.0315 0.0633 0.0888
Loa Loa (eye worm) glutathione reductase 0.0098 0.0154 0.0215
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0113 0.1718
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0079 0.0114 0.0158
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0344 0.0698 0.098
Brugia malayi beta-lactamase 0.0079 0.0113 0.0157
Schistosoma mansoni amine GPCR 0.0055 0.0061 0.0083
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0033 0.0062
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1424 0.308 0.3078
Loa Loa (eye worm) hypothetical protein 0.0444 0.0919 0.1292
Leishmania major cathepsin L-like protease 0.1424 0.308 0.8314
Loa Loa (eye worm) hypothetical protein 0.0058 0.0066 0.0091
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0296 0.0592 0.0831
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0067 0.0086 0.0118
Onchocerca volvulus 0.1424 0.308 0.6256
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.005 0.0098
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0061 0.0059
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0084 0.0124 0.0249
Brugia malayi B-box type zinc-finger protein ncl-1 0.0038 0.0023 0.0029
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.0061 0.0083
Schistosoma mansoni cathepsin B (C01 family) 0.0344 0.0698 0.098
Leishmania major small myristoylated protein 4, putative 0.0606 0.1275 0.3438
Trichomonas vaginalis calcium binding protein, putative 0.0089 0.0136 0.0273
Brugia malayi CHD4 protein 0.0059 0.0068 0.0093
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0047 0.0091
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0188 0.0353 0.0495
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0057 0.0066 0.0207
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0203 0.0387 0.0385
Echinococcus granulosus polycomb protein SCMH1 0.0144 0.0256 0.0358
Brugia malayi Cell death protein 3 precursor 0.0058 0.0066 0.009
Trypanosoma brucei Calpain-like protein 1.2 0.0692 0.1465 0.3954
Trypanosoma cruzi prefoldin subunit, putative 0.0061 0.0074 0.0101
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1511 0.3273 0.4606
Onchocerca volvulus 0.0109 0.0181 0.0362
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0048 0.0046 0.0062
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0082 0.0119 0.038
Mycobacterium ulcerans acyl-CoA synthetase 0.0039 0.0025 0.0361
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0274 0.0544 0.0763
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.043 0.0603
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0029 0.0004 0.0033
Brugia malayi G protein-coupled receptor 0.0055 0.0061 0.0083
Echinococcus multilocularis calpain 5 0.0673 0.1424 0.1422
Entamoeba histolytica protein kinase, putative 0.0359 0.073 0.2366
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0003 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0164 0.0301 0.0422
Trypanosoma cruzi small myristoylated protein 1-1 0.0384 0.0786 0.1105
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0053 0.0057 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0049 0.0096
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.0061 0.0059
Onchocerca volvulus 0.0055 0.0061 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0902 0.1929 0.5205
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0113 0.1076
Trichomonas vaginalis glucosylceramidase, putative 0.0253 0.0498 0.1009
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0033 0.0031
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0223 0.043 0.1157
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0079 0.0114 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0066 0.0084 0.0167
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.0061 0.0059
Brugia malayi Pepsin A precursor 0.0079 0.0114 0.0158
Brugia malayi Kringle domain containing protein 0.0062 0.0075 0.0103
Toxoplasma gondii calcium-dependent protein kinase 0.0092 0.0142 0.0455
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0082 0.0119 0.0117
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0006 0.001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0033 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0386 0.0791 0.1604
Loa Loa (eye worm) hypothetical protein 0.0444 0.0919 0.1292
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0003 0.0001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0788 0.1678 0.236
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0033 0.0044
Schistosoma mansoni cpg binding protein 0.0053 0.0056 0.0077
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0113 0.1076
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.001 0.0135
Echinococcus multilocularis transmembrane protease serine 3 0.0058 0.0066 0.0065
Trypanosoma brucei antigen, putative 0.0673 0.1424 0.3841
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.0061 0.0083
Plasmodium falciparum serine repeat antigen 5 0.0344 0.0698 0.2261
Plasmodium falciparum serine repeat antigen 4 0.0344 0.0698 0.2261
Echinococcus granulosus programmed cell death protein 0.0098 0.0155 0.0216
Echinococcus granulosus caspase 2 0.0058 0.0066 0.009
Plasmodium falciparum thioredoxin reductase 0.0098 0.0154 0.0496
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0053 0.0057 0.0148
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0014 0.0032
Trypanosoma brucei Calpain-like protein 2 0.0673 0.1423 0.3839
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.0061 0.0083
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0706 0.1496 0.1494
Leishmania major cathepsin L-like protease 0.1707 0.3704 1
Toxoplasma gondii aspartyl protease 0.0079 0.0114 0.0364
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0029 0.0088
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0019 0.0024
Mycobacterium leprae Probable lipase LipE 0.0079 0.0113 0.2283
Echinococcus granulosus phd:f box containing protein 0.007 0.0093 0.0128
Loa Loa (eye worm) beta-lactamase 0.0079 0.0113 0.0157
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0223 0.043 0.0603
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0058 0.0066 0.0091
Echinococcus granulosus cathepsin b 0.3248 0.7102 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0788 0.1678 0.5445
Echinococcus granulosus calpain A 0.0673 0.1424 0.2003
Plasmodium vivax vivapain-2 0.1424 0.308 1
Trypanosoma cruzi cysteine peptidase, putative 0.0788 0.1678 0.236
Echinococcus granulosus calmodulin 0.0089 0.0136 0.0189
Echinococcus multilocularis orexin receptor type 2 0.0055 0.0061 0.0059
Loa Loa (eye worm) heterochromatin protein 1 0.0249 0.0489 0.0685
Loa Loa (eye worm) hypothetical protein 0.0055 0.0061 0.0083
Echinococcus multilocularis calmodulin 0.0089 0.0136 0.0134
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0053 0.0057 0.0077
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.0061 0.0083
Giardia lamblia Cysteine protease 0.0344 0.0698 0.2599
Loa Loa (eye worm) hypothetical protein 0.0335 0.0678 0.0953
Brugia malayi hypothetical protein 0.0055 0.0061 0.0083
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0033 0.0044
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0041 0.0029 0.0038
Brugia malayi Cathepsin L-like precursor 0.1424 0.308 0.4334
Schistosoma mansoni hypothetical protein 0.0038 0.0023 0.0029
Trypanosoma cruzi major cysteine proteinase, putative 0.0344 0.0698 0.098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.098 0.21 0.4264
Brugia malayi TAR-binding protein 0.0348 0.0708 0.0994
Toxoplasma gondii EFHC1, putative 0.0089 0.0136 0.0436
Schistosoma mansoni tar DNA-binding protein 0.0348 0.0708 0.0994
Brugia malayi PAN domain containing protein 0.0029 0.0003 0.0001
Plasmodium vivax aspartyl protease, putative 0.0079 0.0114 0.0364
Leishmania major calpain family cysteine protease-like protein 0.0537 0.1124 0.3031
Onchocerca volvulus 0.1424 0.308 0.6256
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0344 0.0698 0.2261
Echinococcus multilocularis zinc finger protein 0.0169 0.0311 0.0309
Schistosoma mansoni neuropeptide receptor 0.0055 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Brugia malayi fibroinase precursor 0.0344 0.0698 0.098
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.0029
Schistosoma mansoni cathepsin C 0.0344 0.0698 0.098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1424 0.308 0.6257
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0089 0.0136 0.0189
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0057 0.0066 0.0207
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.007 0.0093 0.0128
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0018 0.0032
Loa Loa (eye worm) programmed cell death protein 6 0.0092 0.0142 0.0197
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0104 0.0169 0.0339
Loa Loa (eye worm) hypothetical protein 0.0316 0.0636 0.0893
Mycobacterium ulcerans hypothetical protein 0.0058 0.0066 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0315 0.0633 0.1282
Trypanosoma cruzi prefoldin subunit, putative 0.0061 0.0074 0.0101
Entamoeba histolytica cysteine proteinase 2 0.0788 0.1678 0.5445
Loa Loa (eye worm) hypothetical protein 0.0029 0.0003 0.0001
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0066 0.0084 0.0222
Onchocerca volvulus 0.0079 0.0113 0.0224
Schistosoma mansoni hypothetical protein 0.0055 0.0061 0.0083
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0033 0.0031
Toxoplasma gondii prefoldin subunit 6, putative 0.0061 0.0074 0.0234
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0344 0.0698 0.2261
Echinococcus multilocularis centrin 2 0.0089 0.0136 0.0134
Loa Loa (eye worm) hypothetical protein 0.0061 0.0074 0.0101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0344 0.0698 0.1414

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 74 nM Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane ChEMBL. 18294852
IC50 (binding) = 74 nM Displacement of [3H]PK115 from peripheral benzodiazepine receptor in Sprague-Dawley rat cortical membrane ChEMBL. 18294852

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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