Detailed information for compound 1522844

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.403 | Formula: C21H24BrN3O2S
  • H donors: 0 H acceptors: 2 LogP: 3.93 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1CCN(CC1)Cc1ccc2c(c1)ccn2S(=O)(=O)c1ccccc1Br
  • InChi: 1S/C21H24BrN3O2S/c1-2-23-11-13-24(14-12-23)16-17-7-8-20-18(15-17)9-10-25(20)28(26,27)21-6-4-3-5-19(21)22/h3-10,15H,2,11-14,16H2,1H3
  • InChiKey: LKWNMPNQULFQLQ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cholinergic receptor, muscarinic 1 Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Get druggable targets OG5_133042 All targets in OG5_133042
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133074 All targets in OG5_133074
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_145685 All targets in OG5_145685
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_145685 All targets in OG5_145685
Echinococcus multilocularis biogenic amine (5HT) receptor Get druggable targets OG5_133074 All targets in OG5_133074
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133074 All targets in OG5_133074

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi follicle stimulating hormone receptor 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 388 aa 314 aa 23.9 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Onchocerca volvulus 0.0035 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0235 0.0453 0.0453
Plasmodium vivax hypothetical protein, conserved 0.0074 0.01 0.024
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Echinococcus granulosus histone deacetylase 0.0097 0.0151 0.0147
Giardia lamblia Cysteine protease 0.0415 0.0846 0.2274
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0034 0.0013 0.0011
Loa Loa (eye worm) beta-lactamase 0.0074 0.01 0.01
Echinococcus granulosus Tolloid protein 1 0.0084 0.0122 0.0119
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0034 0.0013 0.0013
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0415 0.0846 0.0846
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1676 0.3608 0.3608
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.001 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0234 0.1527
Echinococcus granulosus calpain A 0.4438 0.9658 0.9658
Trichomonas vaginalis calpain, putative 0.0597 0.1245 0.3386
Giardia lamblia High cysteine protein 0.0054 0.0056 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Trichomonas vaginalis hypothetical protein 0.0597 0.1245 0.3386
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0029 0.0025
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.033 0.0661 0.0661
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0163 0.0478
Loa Loa (eye worm) hypothetical protein 0.0415 0.0846 0.0846
Schistosoma mansoni glycogen phosphorylase 0.0113 0.0187 0.0183
Leishmania major hypothetical protein, conserved 0.0074 0.01 0.0226
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Loa Loa (eye worm) hypothetical protein 0.0597 0.1245 0.1245
Brugia malayi cathepsin Z-like cysteine proteinase 0.0415 0.0846 0.0843
Leishmania major hypothetical protein, conserved 0.0211 0.04 0.0932
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0029 0.0025
Trichomonas vaginalis calmodulin, putative 0.0284 0.056 0.1522
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Leishmania major DNA polymerase eta, putative 0.0046 0.0039 0.0082
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0084 0.0121 0.033
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0211 0.04 0.04
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0034 0.0013 0.0009
Entamoeba histolytica calpain large subunit domain III containing protein 0.1092 0.233 0.6447
Echinococcus granulosus hypothetical protein 0.0035 0.0015 0.0011
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.051 0.0506
Plasmodium vivax hypothetical protein, conserved 0.0264 0.0517 0.1392
Toxoplasma gondii cathepsin CPC1 0.0415 0.0846 0.2225
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0725 0.1526 0.1523
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0259 0.0505 0.1181
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.001 0.0006
Echinococcus multilocularis sex peptide receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0052 0.0052 0.0052
Schistosoma mansoni ap endonuclease 0.004 0.0026 0.0022
Loa Loa (eye worm) matrixin family protein 0.0053 0.0055 0.0055
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0235 0.0453 0.0449
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0306 0.0609 0.0606
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1152 0.2462 0.5789
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.01 0.01
Schistosoma mansoni opsin-like receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Leishmania major META domain containing protein 0.0211 0.04 0.0932
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0267 0.0523 0.052
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0211 0.04 0.0396
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0511 0.1058 0.1058
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.024 0.0463 0.1214
Chlamydia trachomatis glycogen phosphorylase 0.0113 0.0187 1
Onchocerca volvulus 0.1676 0.3608 0.6702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0211 0.04 0.0932
Onchocerca volvulus 0.0035 0.0015 0.0015
Loa Loa (eye worm) Notch2 0.0055 0.0059 0.0059
Brugia malayi Trypsin family protein 0.0235 0.0453 0.045
Brugia malayi putative neuropeptide receptor NPR1 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0235 0.0453 0.0453
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.001 0.0006
Trypanosoma cruzi I/6 autoantigen, putative 0.0259 0.0505 0.0502
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.01 0.0096
Brugia malayi Proteasome subunit alpha type 7-1 0.0034 0.0013 0.001
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0234 0.045 0.1342
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0597 0.1245 0.3386
Loa Loa (eye worm) hypothetical protein 0.0155 0.0277 0.0277
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0174 0.0319 0.0315
Plasmodium falciparum prefoldin subunit 6, putative 0.0062 0.0074 0.0171
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0415 0.0846 0.23
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0016 0.0008
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.257 0.5567 0.5567
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0034 0.0013 0.0009
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1956 0.4221 0.4219
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0385 0.0782 0.0778
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0026 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0415 0.0846 0.2302
Brugia malayi programmed cell death protein 6 0.0259 0.0505 0.0502
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0055 0.0059 0.0097
Echinococcus granulosus Proteasome subunit alpha type 7 0.0034 0.0013 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0035 0.0015 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Echinococcus multilocularis programmed cell death protein 0.0284 0.056 0.0556
Plasmodium vivax aspartyl proteinase, putative 0.0093 0.0142 0.0355
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0034 0.0013 0.0009
Onchocerca volvulus 0.0035 0.0015 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0026 0.0022
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0034 0.0013 0.0062
Schistosoma mansoni cathepsin C 0.0415 0.0846 0.0843
Schistosoma mansoni neuropeptide receptor 0.0035 0.0015 0.0011
Leishmania major calmodulin, putative 0.0259 0.0505 0.1181
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0034 0.0013 0.0009
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0035 0.0015 0.0011
Trypanosoma cruzi centrin-3 0.0284 0.056 0.0556
Toxoplasma gondii aldehyde dehydrogenase 0.0135 0.0234 0.0607
Echinococcus multilocularis thyroid hormone receptor alpha 0.0161 0.0292 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Echinococcus multilocularis peroxidasin 0.03 0.0596 0.0592
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0015 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0034 0.0013 0.0009
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1956 0.4221 0.4219
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0267 0.0523 0.1223
Trichomonas vaginalis calcium binding protein, putative 0.0284 0.056 0.1522
Leishmania major proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0022
Loa Loa (eye worm) PAN domain-containing protein 0.0074 0.0101 0.0101
Echinococcus granulosus histone deacetylase 7 0.0097 0.0151 0.0147
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0034 0.0013 0.0009
Echinococcus granulosus g protein coupled receptor 0.0035 0.0015 0.0011
Echinococcus granulosus Transglutaminase 0.0035 0.0015 0.0011
Brugia malayi hypothetical protein 0.0261 0.051 0.0507
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0029 0.0025
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1108 0.2366 0.5562
Plasmodium vivax hypothetical protein, conserved 0.0211 0.04 0.1068
Trypanosoma brucei calpain-like protein, putative 0.1688 0.3637 0.8553
Brugia malayi Thioredoxin family protein 0.0035 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0415 0.0846 0.0846
Loa Loa (eye worm) hypothetical protein 0.0052 0.0052 0.0052
Plasmodium vivax proteasome subunit beta type-2, putative 0.0084 0.0121 0.0299
Brugia malayi Calcium binding EGF domain containing protein 0.0055 0.0059 0.0055
Brugia malayi Thioredoxin reductase 0.0102 0.0163 0.0159
Loa Loa (eye worm) hypothetical protein 0.0059 0.0067 0.0067
Schistosoma mansoni hypothetical protein 0.0259 0.0505 0.0502
Schistosoma mansoni cpg binding protein 0.0063 0.0076 0.0072
Mycobacterium ulcerans proteasome PrcB 0.0174 0.0319 0.2094
Schistosoma mansoni calmodulin 0.0259 0.0505 0.0502
Schistosoma mansoni Mername-AA248 (C02 family) 0.1688 0.3637 0.3634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Toxoplasma gondii PAN domain-containing protein 0.0074 0.0101 0.0257
Onchocerca volvulus 0.0074 0.01 0.0173
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0015 0.0011
Brugia malayi prolyl oligopeptidase family protein 0.0553 0.115 0.1147
Echinococcus granulosus tachykinin peptides receptor 99D 0.1475 0.3169 0.3167
Leishmania major calmodulin, putative 0.0259 0.0505 0.1181
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1676 0.3608 0.3606
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1881 0.4058 0.4056
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0385 0.0782 0.0778
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0084 0.0122 0.0122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1881 0.4058 0.4056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Echinococcus granulosus chromobox protein 1 0.0071 0.0094 0.009
Echinococcus granulosus histone deacetylase 6 0.0097 0.0151 0.0147
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0016 0.0044
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0013 0.0035
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0597 0.1245 0.2923
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0054 0.0056 0.0052
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0177 0.0325 0.0756
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Echinococcus multilocularis protein jagged 1 0.0054 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0135 0.0234 0.0625
Mycobacterium ulcerans hypothetical protein 0.0035 0.0015 0.0074
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0807 0.1707 0.4009
Brugia malayi Cytochrome P450 family protein 0.0067 0.0085 0.0081
Brugia malayi Papain family cysteine protease containing protein 0.0415 0.0846 0.0843
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0029 0.0025
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0034 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0052 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0049 0.0046 0.0278
Loa Loa (eye worm) proteasome subunit beta type 3 0.0034 0.0013 0.0013
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0183 0.0339 0.0335
Giardia lamblia Encystation-specific protease 0.0415 0.0846 0.2274
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Echinococcus multilocularis neuronal calcium sensor 0.0259 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0305 0.0606 0.0606
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Brugia malayi proteasome subunit alpha type 6 0.0034 0.0013 0.001
Echinococcus multilocularis cathepsin L cysteine protease 0.1676 0.3608 0.3606
Plasmodium vivax vivapain-2 0.1676 0.3608 0.9922
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0026 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0091 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0183 0.0339 0.0339
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0029 0.0025
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0026 1
Toxoplasma gondii heat shock protein hslv, putative 0.0034 0.0013 0.0025
Onchocerca volvulus 0.1676 0.3608 0.6702
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.033 0.0661 0.0657
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0415 0.0846 0.2318
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0257 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus multilocularis endothelin converting enzyme 1 0.0098 0.0153 0.015
Brugia malayi Eukaryotic aspartyl protease family protein 0.0093 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0151 0.0269 0.0269
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0489 0.101 0.1007
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0034 0.0013 0.0009
Toxoplasma gondii aspartyl protease ASP3 0.0172 0.0316 0.0824
Mycobacterium tuberculosis Conserved protein 0.0035 0.0015 0.0034
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0034 0.0013 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.0234 0.023
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0072 0.0069
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0026 0.0026
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0035 0.0015 0.0014
Trypanosoma brucei small myristoylated protein 1-2 0.0363 0.0734 0.172
Schistosoma mansoni cathepsin B (C01 family) 0.0415 0.0846 0.0843
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.001 0.0006
Schistosoma mansoni hypothetical protein 0.0346 0.0696 0.0693
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0135 0.0234 0.0542
Onchocerca volvulus Prolyl endopeptidase homolog 0.1759 0.3791 0.7042
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Echinococcus granulosus inhibitor of apoptosis protein 0.0183 0.0339 0.0335
Entamoeba histolytica glycogenphosphorylase, putative 0.0049 0.0046 0.0101
Echinococcus granulosus tissue type plasminogen activator 0.0185 0.0343 0.034
Schistosoma mansoni hypothetical protein 0.0456 0.0938 0.0934
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0035 0.0015 0.0014
Onchocerca volvulus 0.0074 0.0101 0.0176
Schistosoma mansoni calpain-7 (C02 family) 0.1691 0.3643 0.3641
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0011
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0051 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0079
Schistosoma mansoni lamin 0.0055 0.006 0.0056
Brugia malayi proteasome subunit alpha type 3 0.0034 0.0013 0.001
Entamoeba histolytica glycogen phosphorylase, putative 0.0113 0.0187 0.0493
Schistosoma mansoni histone deacetylase 4 5 0.0097 0.0151 0.0147
Brugia malayi RE15519p 0.0035 0.0015 0.0011
Toxoplasma gondii histone deacetylase HDAC5 0.0042 0.003 0.007
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Schistosoma mansoni calpain C (C02 family) 0.1688 0.3637 0.3634
Loa Loa (eye worm) hypothetical protein 0.2485 0.5381 0.5381
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Plasmodium falciparum serine repeat antigen 2 0.0415 0.0846 0.2318
Echinococcus granulosus G protein coupled receptor 139 0.0035 0.0015 0.0011
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4594 1 1
Giardia lamblia Cathepsin L precursor 0.0415 0.0846 0.2274
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0006
Brugia malayi Calcium binding EGF domain containing protein 0.0059 0.0067 0.0064
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.01 0.0289
Trypanosoma brucei hypothetical protein, conserved 0.0259 0.0505 0.1181
Entamoeba histolytica cysteine proteinase, putative 0.1676 0.3608 1
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0034 0.0013 0.0009
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0034 0.0013 0.0022
Toxoplasma gondii histone deacetylase HDAC3 0.0086 0.0127 0.0327
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0597 0.1245 0.3386
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0415 0.0846 0.0846
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0034 0.0013 0.0022
Brugia malayi sulfakinin receptor protein 0.0035 0.0015 0.0011
Schistosoma mansoni amine GPCR 0.0035 0.0015 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0015 0.0011
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0415 0.0846 0.0843
Brugia malayi cathepsin L-like cysteine proteinase 0.0415 0.0846 0.0843
Brugia malayi prolyl oligopeptidase family protein 0.0306 0.0609 0.0606
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0015 0.0011
Trypanosoma cruzi prefoldin subunit, putative 0.0062 0.0074 0.0071
Onchocerca volvulus 0.0264 0.0517 0.095
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0235 0.0453 0.0449
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0034 0.0013 0.0009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0035 0.0015 0.0011
Brugia malayi EF hand family protein 0.0259 0.0505 0.0502
Brugia malayi Cathepsin L-like precursor 0.1164 0.2489 0.2486
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0014
Echinococcus multilocularis histone deacetylase 7 0.0097 0.0151 0.0147
Schistosoma mansoni DNA polymerase eta 0.0046 0.0039 0.0035
Onchocerca volvulus 0.0035 0.0015 0.0015
Trypanosoma cruzi prolyl endopeptidase 0.1759 0.3791 0.3789
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0163 0.0413
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0026 1
Echinococcus granulosus cathepsin b 0.4594 1 1
Echinococcus multilocularis calpain 0.1688 0.3637 0.3634
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.0163 0.0159
Echinococcus granulosus sodium channel protein 0.004 0.0025 0.0022
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0807 0.1707 0.1704
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0415 0.0846 0.23
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0511 0.1058 0.1058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0415 0.0846 0.2302
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.006 0.0056
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0029 0.0026
Trypanosoma brucei Calpain-like protein CALP1.3 0.0807 0.1707 0.4009
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0235 0.0453 0.0449
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.001 0.0006
Schistosoma mansoni reticulocalbin 0.0264 0.0517 0.0514
Echinococcus multilocularis allatostatin A receptor 0.0035 0.0015 0.0011
Echinococcus granulosus ryanodine receptor 44f 0.0305 0.0606 0.0603
Entamoeba histolytica cysteine protease, putative 0.0415 0.0846 0.2326
Loa Loa (eye worm) histone deacetylase 0.0097 0.0151 0.0151
Onchocerca volvulus Cathepsin F homolog 0.1676 0.3608 0.6702
Onchocerca volvulus 0.0035 0.0015 0.0015
Giardia lamblia Cathepsin B precursor 0.0415 0.0846 0.2274
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0046 0.0101
Brugia malayi Delta serrate ligand family protein 0.0054 0.0056 0.0052
Brugia malayi ImpB/MucB/SamB family protein 0.0046 0.0039 0.0035
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0235 0.0453 0.045
Loa Loa (eye worm) EF hand family protein 0.0259 0.0505 0.0505
Plasmodium vivax aspartyl protease, putative 0.0172 0.0316 0.0836
Schistosoma mansoni gamma-secretase subunit aph-1 0.0257 0.05 0.0497
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0084 0.0121 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0151 0.0269 0.0269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.0661 0.0657
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0034 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0098 0.0153 0.0153
Trichomonas vaginalis peptide N-glycanase, putative 0.0035 0.0015 0.0041
Leishmania major proteasome beta 7 subunit, putative 0.0034 0.0013 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.0686 0.1865
Giardia lamblia Cathepsin B precursor 0.1707 0.3677 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0015 0.0034
Onchocerca volvulus 0.0035 0.0015 0.0015
Leishmania major calmodulin-like protein 0.0259 0.0505 0.1181
Echinococcus granulosus caspase 2 0.0155 0.0277 0.0273
Entamoeba histolytica hypothetical protein 0.0041 0.0029 0.0055
Plasmodium vivax SET domain protein, putative 0.0159 0.0286 0.0753
Brugia malayi Animal haem peroxidase family protein 0.03 0.0596 0.0593
Trichomonas vaginalis glycogen phosphorylase, putative 0.0113 0.0187 0.0507
Brugia malayi Melatonin receptor type 1A 0.0035 0.0015 0.0011
Schistosoma mansoni reticulocalbin 0.0259 0.0505 0.0502
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0129 0.022 0.0217
Brugia malayi Calcium binding EGF domain containing protein 0.0055 0.0059 0.0055
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0015 0.0011
Giardia lamblia Glycogen phosphorylase 0.0113 0.0187 0.0474
Onchocerca volvulus 0.0259 0.0505 0.0928
Brugia malayi Dopamine receptor protein 1 0.0035 0.0015 0.0011
Leishmania major hypothetical protein, conserved 0.0051 0.0051 0.0111
Toxoplasma gondii PAN domain-containing protein 0.0074 0.0101 0.0257
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Toxoplasma gondii peptidase family M13 protein 0.0098 0.0153 0.0395
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Brugia malayi CXXC zinc finger family protein 0.0063 0.0076 0.0073
Giardia lamblia Cysteine protease 0.0415 0.0846 0.2274
Leishmania major hypothetical protein, conserved 0.0211 0.04 0.0932
Entamoeba histolytica cysteine proteinase 2 0.0926 0.1966 0.5437
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1676 0.3608 0.3608
Onchocerca volvulus Neuropeptide F receptor homolog 0.0035 0.0015 0.0015
Echinococcus granulosus sex peptide receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Leishmania major proteasome beta 2 subunit, putative 0.0084 0.0121 0.0277
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Schistosoma mansoni hypothetical protein 0.0053 0.0055 0.0051
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0717 0.1509 0.3545
Leishmania major prefoldin subunit, putative 0.0062 0.0074 0.0166
Toxoplasma gondii calcium binding egf domain-containing protein 0.0053 0.0055 0.0137
Brugia malayi hypothetical protein 0.0093 0.0142 0.0138
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0029 0.0026
Schistosoma mansoni neuronal calcium sensor 0.0259 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0055
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.0127 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Loa Loa (eye worm) PAS-3 protein 0.0034 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Toxoplasma gondii kringle domain-containing protein 0.0185 0.0343 0.0897
Loa Loa (eye worm) calpain D 0.0597 0.1245 0.1245
Echinococcus granulosus biogenic amine 5HT receptor 0.0489 0.101 0.1007
Plasmodium falciparum thioredoxin reductase 0.0102 0.0163 0.0416
Onchocerca volvulus 0.0035 0.0015 0.0015
Echinococcus granulosus protein jagged 1 0.0054 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Trichomonas vaginalis glycogen phosphorylase, putative 0.0113 0.0187 0.0507
Schistosoma mansoni cell polarity protein 0.0054 0.0056 0.0052
Trypanosoma brucei calmodulin, putative 0.0259 0.0505 0.1181
Brugia malayi Proteasome A-type and B-type family protein 0.0034 0.0013 0.001
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Brugia malayi Cathepsin L-like precursor 0.1676 0.3608 0.3606
Brugia malayi neuropeptide F receptor 0.0035 0.0015 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0308 0.0613 0.1433
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0409 0.0835 0.0832
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0259 0.0505 0.0502
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0035 0.0015 0.0011
Schistosoma mansoni neuronal calcium sensor 0.0259 0.0505 0.0502
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0029 0.0025
Schistosoma mansoni neuropeptide receptor 0.0035 0.0015 0.0011
Brugia malayi Animal haem peroxidase family protein 0.03 0.0596 0.0593
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1707 0.3677 1
Echinococcus granulosus histone deacetylase 3 0.0086 0.0127 0.0124
Loa Loa (eye worm) calpain family protein 1 0.4173 0.9079 0.9079
Echinococcus multilocularis EF hand domain containing family member A2 0.0259 0.0505 0.0502
Toxoplasma gondii EF hand domain-containing protein 0.0259 0.0505 0.1325
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0035 0.0015 0.0011
Giardia lamblia Cathepsin L precursor 0.0415 0.0846 0.2274
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0034 0.0013 0.0009
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.01 0.0639
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0864 0.183 0.43
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0072 0.0072
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0034 0.0013 0.0009
Echinococcus granulosus somatostatin receptor 0.0035 0.0015 0.0011
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.01 0.0289
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.01 0.0289
Mycobacterium ulcerans lipase LipD 0.0074 0.01 0.0639
Trypanosoma cruzi centrin, putative 0.0284 0.056 0.0556
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0086 0.0127 0.0346
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0415 0.0846 0.2326
Echinococcus multilocularis calmodulin 0.0259 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0054 0.0057 0.0056
Plasmodium vivax aspartyl proteinase, putative 0.024 0.0463 0.1243
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0051 0.0125
Brugia malayi calcium-binding protein 0.0259 0.0505 0.0502
Echinococcus granulosus Dipeptidyl peptidase 9 0.0306 0.0609 0.0606
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0926 0.1966 0.462
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0415 0.0846 0.0843
Trichomonas vaginalis conserved hypothetical protein 0.0259 0.0505 0.1374
Brugia malayi AKH receptor 0.0035 0.0015 0.0011
Echinococcus granulosus chromobox protein 1 0.0071 0.0094 0.009
Echinococcus multilocularis protein jagged 2 0.0054 0.0056 0.0052
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0159 0.0286 0.0745
Loa Loa (eye worm) notch protein 0.0055 0.0059 0.0059
Entamoeba histolytica grainin 2 0.0284 0.056 0.153
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0015 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0035 0.0015 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0029 0.0025
Entamoeba histolytica cysteine protease, putative 0.0415 0.0846 0.2326
Brugia malayi carbohydrate phosphorylase 0.0113 0.0187 0.0183
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Onchocerca volvulus 0.0054 0.0056 0.0091
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0015 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.04 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Brugia malayi Proteasome A-type and B-type family protein 0.0034 0.0013 0.001
Leishmania major histone deacetylase, putative 0.0097 0.0151 0.0346
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0014 0.0011
Leishmania major proteasome alpha 3 subunit, putative 0.0034 0.0013 0.0022
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0211 0.04 0.0396
Leishmania major small myristoylated protein-3, putative 0.0308 0.0613 0.1433
Brugia malayi prolyl oligopeptidase family protein 0.0211 0.04 0.0397
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0717 0.1509 1
Entamoeba histolytica calmodulin, putative 0.0259 0.0505 0.1379
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0306 0.0609 0.1426
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0034 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus multilocularis proteasome (prosome, macropain) 0.0174 0.0319 0.0315
Onchocerca volvulus Slit protein homolog 0.0054 0.0056 0.0091
Loa Loa (eye worm) hypothetical protein 0.0406 0.0827 0.0826
Plasmodium falciparum plasmepsin VIII, putative 0.0093 0.0142 0.0358
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0034 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.0119 0.0199 0.0196
Brugia malayi EF hand family protein 0.0264 0.0517 0.0514
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4594 1 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0267 0.0523 0.1223
Plasmodium falciparum cysteine repeat modular protein 1 0.0185 0.0343 0.0918
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0029 0.0025
Brugia malayi proteasome subunit beta type 3 0.0034 0.0013 0.001
Trypanosoma cruzi 20S proteasome subunit 0.0084 0.0121 0.0118
Plasmodium falciparum histone deacetylase, putative 0.0097 0.0151 0.0383
Loa Loa (eye worm) hypothetical protein 0.0235 0.0453 0.0453
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0034 0.0013 0.0009
Plasmodium falciparum histone deacetylase 1 0.0086 0.0127 0.0318
Plasmodium falciparum serine repeat antigen 7 0.0415 0.0846 0.2318
Giardia lamblia Proteasome subunit beta type 2 0.0084 0.0121 0.0296
Trypanosoma cruzi calmodulin, putative 0.0259 0.0505 0.0502
Trypanosoma brucei conserved protein 0.022 0.0419 0.0979
Leishmania major hypothetical protein, conserved 0.0259 0.0505 0.1181
Loa Loa (eye worm) DEAH box polypeptide 35 0.0031 0.0007 0.0007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0267 0.0523 0.1223
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0015 0.0011
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) ryanodine receptor 0.0183 0.0339 0.0339
Schistosoma mansoni cathepsin D (A01 family) 0.0707 0.1488 0.1485
Loa Loa (eye worm) hypothetical protein 0.1164 0.2489 0.2489
Entamoeba histolytica cysteine proteinase, putative 0.1676 0.3608 1
Echinococcus multilocularis chromobox protein 1 0.0071 0.0094 0.009
Echinococcus multilocularis caspase 2 0.0155 0.0277 0.0273
Toxoplasma gondii microneme protein MIC17C 0.0074 0.0101 0.0257
Toxoplasma gondii PAN/Apple domain-containing protein 0.0074 0.0101 0.0257
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0029 0.0025
Schistosoma mansoni opsin-like receptor 0.0035 0.0015 0.0011
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1956 0.4221 0.993
Echinococcus granulosus EF HAND 1 calcium binding site 0.0259 0.0505 0.0502
Entamoeba histolytica cysteine proteinase, putative 0.0926 0.1966 0.5437
Leishmania major small myristoylated protein-1 0.0363 0.0734 0.172
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1707 0.3677 0.3675
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0954 0.2027 0.2024
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0097
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0072 0.0069
Mycobacterium tuberculosis Long conserved protein 0.0035 0.0015 0.0034
Trichomonas vaginalis calcineurin B subunit, putative 0.0259 0.0505 0.1374
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0035 0.0015 0.0011
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0211 0.04 0.0932
Plasmodium vivax prefoldin subunit 6, putative 0.0062 0.0074 0.0169
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.001 0.0006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0807 0.1707 0.1704
Onchocerca volvulus Peroxidasin homolog 0.03 0.0596 0.1096
Onchocerca volvulus Matrix metalloproteinase homolog 0.0049 0.0046 0.0072
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0067 0.0085 0.0537
Echinococcus granulosus calpain A 0.1688 0.3637 0.3634
Loa Loa (eye worm) hypothetical protein 0.0093 0.0142 0.0142
Echinococcus granulosus 7tm_1 domain containing protein 0.0035 0.0015 0.0011
Brugia malayi Pre-SET motif family protein 0.0159 0.0286 0.0283
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Onchocerca volvulus 0.1676 0.3608 0.6702
Brugia malayi ecdysteroid receptor 0.0033 0.001 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0072 0.0069
Loa Loa (eye worm) cysteine protease 0.1676 0.3608 0.3608
Schistosoma mansoni notch 0.0054 0.0056 0.0052
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0174 0.0319 0.0742
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.01
Echinococcus multilocularis histone deacetylase 6 0.0097 0.0151 0.0147
Giardia lamblia Transglutaminase/protease, putative 0.0035 0.0015 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0007 0.0006
Entamoeba histolytica calcium binding family protein 0.0259 0.0505 0.1379
Toxoplasma gondii microneme protein, putative 0.0074 0.0101 0.0257
Echinococcus granulosus laminin 0.0053 0.0055 0.0052
Schistosoma mansoni centrin-related 0.0259 0.0505 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.04 0.0396
Brugia malayi GCC2 and GCC3 family protein 0.0055 0.0059 0.0055
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0308 0.0613 0.0609
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0807 0.1707 0.4009
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0921 0.1956 0.4596
Leishmania major histone deacetylase, putative 0.0086 0.0127 0.0291
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0009
Schistosoma mansoni notch 0.0054 0.0056 0.0052
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0211 0.04 0.1047
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0573 0.1193 0.119
Schistosoma mansoni hypothetical protein 0.0053 0.0054 0.005
Plasmodium vivax plasmepsin IV, putative 0.024 0.0463 0.1243
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Loa Loa (eye worm) hypothetical protein 0.3082 0.6688 0.6688
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0235 0.0453 0.0453
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0015 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0235 0.0453 0.0449
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4594 1 1
Trypanosoma cruzi cruzipain precursor, putative 0.1969 0.4251 0.4249
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0717 0.1509 0.3545
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0035 0.0015 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.01 0.0096
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0094 0.0094
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0016 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.001 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0015 0.0011
Schistosoma mansoni calmodulin 0.0259 0.0505 0.0502
Schistosoma mansoni laminin gamma-3 chain 0.0054 0.0056 0.0052
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.005 0.0046
Schistosoma mansoni chromobox protein 0.0071 0.0094 0.009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.01 0.0289
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0029
Entamoeba histolytica cysteine protease, putative 0.0415 0.0846 0.2326
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0034 0.0013 0.0013
Trypanosoma cruzi cysteine proteinase, putative 0.0926 0.1966 0.1963
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0072 0.0069
Brugia malayi G-protein coupled receptor 0.0035 0.0015 0.0011
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.4173 0.9079 0.9079
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.001 0.0006
Echinococcus multilocularis tumor protein p63 0.0369 0.0746 0.0743
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0306 0.0609 0.0606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0926 0.1966 0.5346
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0183 0.0339 0.0335
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.001 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.0127 0.0346
Echinococcus granulosus protein jagged 2 0.0054 0.0056 0.0052
Echinococcus granulosus cathepsin b 0.4594 1 1
Loa Loa (eye worm) transcription factor SMAD2 0.0368 0.0744 0.0744
Schistosoma mansoni neprilysin-2 (M13 family) 0.005 0.0047 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Giardia lamblia Cathepsin L-like protease 0.0415 0.0846 0.2274
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0159 0.0286 0.0282
Echinococcus multilocularis glycogen phosphorylase 0.0113 0.0187 0.0183
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1108 0.2366 0.5562
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0034 0.0013 0.0022
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.033 0.0661 0.0657
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0034 0.0013 0.0022
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0029 0.0026
Brugia malayi Probable ATP-dependent helicase DHX35 0.0031 0.0007 0.0004
Plasmodium vivax glutathione reductase, putative 0.0102 0.0163 0.0413
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0211 0.04 0.0396
Echinococcus granulosus fmrfamide receptor 0.0035 0.0015 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0015 0.0011
Schistosoma mansoni lamin 0.0055 0.006 0.0056
Echinococcus granulosus Glycosyl transferase family 35 0.0113 0.0187 0.0183
Giardia lamblia Cathepsin B precursor 0.0415 0.0846 0.2274
Onchocerca volvulus Arrow homolog 0.0052 0.0052 0.0085
Brugia malayi calpain 5 0.0597 0.1245 0.1242
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0097
Echinococcus granulosus geminin 0.0346 0.0696 0.0693
Giardia lamblia Cathepsin B precursor 0.1707 0.3677 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0029
Trichomonas vaginalis calcium binding protein, putative 0.0259 0.0505 0.1374
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4594 1 1
Echinococcus multilocularis histone deacetylase 1 0.0086 0.0127 0.0124
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Entamoeba histolytica hypothetical protein 0.0415 0.0846 0.2326
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0936 0.1988 0.4671
Trypanosoma cruzi hypothetical protein, conserved 0.0185 0.0343 0.034
Brugia malayi proteasome subunit alpha type 1 0.0034 0.0013 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0259 0.0505 0.0502
Brugia malayi Hemopexin family protein 0.0031 0.0007 0.0004
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0093 0.0142 0.0364
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0308 0.0613 0.0609
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1707 0.3677 0.3675
Brugia malayi Serotonin receptor 0.0035 0.0015 0.0011
Entamoeba histolytica prolyl oligopeptidase family protein 0.0211 0.04 0.1086
Trypanosoma brucei calpain, putative 0.0597 0.1245 0.2923
Plasmodium falciparum plasmepsin VI 0.024 0.0463 0.1253
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.001 0.001
Echinococcus granulosus cathepsin L 0.0415 0.0846 0.0843
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0135 0.0234 0.023
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0035 0.0015 0.0014
Echinococcus granulosus proteasome subunit beta type 7 0.0034 0.0013 0.0009
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0034 0.0013 0.0009
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0471 0.0971 0.2908
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Entamoeba histolytica prolyl oligopeptidase family protein 0.0211 0.04 0.1086
Schistosoma mansoni neuronal calcium sensor 0.0259 0.0505 0.0502
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0034 0.0013 0.0011
Trypanosoma brucei hypothetical protein 0.0864 0.183 0.43
Plasmodium falciparum cysteine proteinase falcipain 3 0.1676 0.3608 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0234 0.1527
Entamoeba histolytica histone deacetylase, putative 0.0086 0.0127 0.0329
Trypanosoma cruzi calmodulin, putative 0.0259 0.0505 0.0502
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.001 0.0006
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Entamoeba histolytica hypothetical protein 0.0041 0.0029 0.0055
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.024 0.0463 0.046
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0029 0.0025
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0022
Onchocerca volvulus 0.0035 0.0015 0.0015
Echinococcus granulosus histone deacetylase 8 0.0042 0.0029 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.001 0.001
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0034 0.0013 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0234 0.045 0.1342
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0029 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0015 0.0011
Echinococcus granulosus g-protein coupled receptor 0.0035 0.0015 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0406 0.0827 0.0823
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0415 0.0846 0.2318
Echinococcus granulosus serotonin receptor 0.0035 0.0015 0.0011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0489 0.101 0.1007
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0174 0.0319 0.2094
Brugia malayi histone deacetylase 3 (HD3) 0.0086 0.0127 0.0124
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.005 0.0047 0.0043
Echinococcus granulosus neuropeptide s receptor 0.0035 0.0015 0.0011
Brugia malayi hypothetical protein 0.0033 0.0011 0.0008
Echinococcus granulosus transmembrane protease serine 3 0.0235 0.0453 0.0449
Echinococcus granulosus alpha 1A adrenergic receptor 0.0035 0.0015 0.0011
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0103 0.01
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0015 0.0011
Echinococcus multilocularis calumenin 0.0264 0.0517 0.0514
Loa Loa (eye worm) calpain 5 0.1092 0.233 0.233
Echinococcus granulosus lamin 0.0055 0.006 0.0056
Brugia malayi hypothetical protein 0.0124 0.0211 0.0208
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.01 0.0096
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trypanosoma brucei histone deacetylase 4 0.0097 0.0151 0.0346
Loa Loa (eye worm) ryanodine receptor 0.0114 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Echinococcus multilocularis ryanodine receptor 44f 0.0393 0.08 0.0797
Trypanosoma brucei trypanothione reductase 0.0102 0.0163 0.0374
Onchocerca volvulus Putative cubilin 0.0059 0.0067 0.0113
Echinococcus granulosus muscleblind protein 0.0151 0.0269 0.0266
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0061 0.0072 0.0069
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0015 0.0034
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0029 0.0029
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0034 0.0013 0.0009
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0026 0.0036
Schistosoma mansoni egf-like domain protein 0.0052 0.0052 0.0049
Plasmodium falciparum proteasome subunit beta type-5 0.0174 0.0319 0.0851
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0211 0.04 0.0932
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.001 0.001
Giardia lamblia Histone deacetylase 0.0086 0.0127 0.0312
Schistosoma mansoni slit 0.0054 0.0056 0.0052
Onchocerca volvulus 0.0063 0.0076 0.0129
Toxoplasma gondii microneme protein MIC17A 0.0074 0.0101 0.0257
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0029 0.0025
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0015 0.0011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.026 0.0507 0.1514
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0174 0.0319 0.0867
Onchocerca volvulus Peroxidase homolog 0.03 0.0596 0.1096
Brugia malayi cathepsin F-like cysteine proteinase 0.0511 0.1058 0.1055
Loa Loa (eye worm) prolyl oligopeptidase 0.0553 0.115 0.115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Brugia malayi aspartic protease BmAsp-1, identical 0.0093 0.0142 0.0138
Echinococcus multilocularis Mastin 0.0235 0.0453 0.0449
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0035 0.0015 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0921 0.1956 0.1953
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0034 0.0013 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.04 0.0396
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0011
Schistosoma mansoni hypothetical protein 0.0031 0.0007 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0415 0.0846 0.2302
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0259 0.0505 0.0502
Onchocerca volvulus 0.0183 0.0339 0.0618
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0029 0.0026
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Loa Loa (eye worm) melatonin receptor type 1A 0.0035 0.0015 0.0014
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.001 0.0006
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0807 0.1707 0.4009
Leishmania major DNA polymerase eta, putative 0.0032 0.0009 0.0012
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0026 0.0067
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0135 0.0234 0.0615
Trypanosoma cruzi major cysteine proteinase, putative 0.0708 0.1489 0.1486
Onchocerca volvulus 0.0054 0.0056 0.0091
Echinococcus multilocularis neurogenic locus notch protein 0.0054 0.0056 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Echinococcus multilocularis histone deacetylase 0.0097 0.0151 0.0147
Loa Loa (eye worm) hypothetical protein 0.0031 0.0007 0.0007
Echinococcus granulosus cathepsin l cysteine peptidase 0.1676 0.3608 0.3606
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0034 0.0013 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.001 0.0006
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0013 0.0022
Mycobacterium ulcerans proteasome PrcA 0.0034 0.0013 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Trypanosoma brucei Aph-1 protein, putative 0.01 0.0157 0.0361
Echinococcus granulosus neurocalcin 0.0259 0.0505 0.0502
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0015 0.0011
Trichomonas vaginalis esterase, putative 0.0074 0.01 0.0272
Echinococcus multilocularis laminin 0.0053 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.01
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0034 0.0013 0.0022
Brugia malayi Angiotensin-converting enzyme family protein 0.257 0.5567 0.5565
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0415 0.0846 0.0846
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4432 0.9646 0.9646
Echinococcus granulosus tar DNA binding protein 0.0061 0.0072 0.0069
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Onchocerca volvulus 0.0033 0.001 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0415 0.0846 0.2302
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.001 0.0006
Echinococcus multilocularis Glycosyl transferase, family 35 0.0113 0.0187 0.0183
Entamoeba histolytica cysteine proteinase, putative 0.1164 0.2489 0.6889
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0415 0.0846 0.2274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0415 0.0846 0.2302
Echinococcus multilocularis proteasome subunit beta type 7 0.0034 0.0013 0.0009
Brugia malayi notch-like transmembrane receptor 0.0054 0.0056 0.0052
Echinococcus granulosus microtubule associated protein 2 0.1507 0.324 0.3238
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0269 0.0266
Echinococcus multilocularis muscleblind protein 0.0151 0.0269 0.0266
Trypanosoma cruzi cysteine protease, putative 0.0926 0.1966 0.1963
Echinococcus granulosus programmed cell death protein 6 0.003 0.0004 0.0001
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0259 0.0505 0.0502
Entamoeba histolytica cysteine proteinase, putative 0.0926 0.1966 0.5437
Trypanosoma cruzi cytochrome P450, putative 0.0067 0.0085 0.0081
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0234 0.1527
Plasmodium vivax proteasome subunit beta type-5, putative 0.0174 0.0319 0.0844
Leishmania major cysteine peptidase A (CPA) 0.1676 0.3608 0.8486
Brugia malayi Pre-SET motif family protein 0.1099 0.2345 0.2342
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0597 0.1245 0.3386
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0029 0.0026
Toxoplasma gondii microneme protein MIC17B 0.0074 0.0101 0.0257
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0029 0.0079
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0034 0.0013 0.0013
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Leishmania major cathepsin L-like protease 0.1676 0.3608 0.8486
Echinococcus multilocularis hypothetical protein 0.1688 0.3637 0.3634
Mycobacterium tuberculosis Probable peptidase 0.0717 0.1509 0.4527
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0015 0.0011
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0051 0.0047
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0234 0.045 0.1342
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.026 0.0507 0.1514
Schistosoma mansoni neuropeptide receptor 0.0035 0.0015 0.0011
Toxoplasma gondii aspartyl protease ASP1 0.024 0.0463 0.1214
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1676 0.3608 1
Echinococcus multilocularis neurogenic locus protein delta 0.0054 0.0056 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Plasmodium falciparum serine repeat antigen 6 0.0415 0.0846 0.2318
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0034 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.0926 0.1966 0.1963
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0034 0.0013 0.0009
Plasmodium vivax vivapain-3 0.0926 0.1966 0.539
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0553 0.115 0.1147
Giardia lamblia Cathepsin L-like protease 0.0415 0.0846 0.2274
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0415 0.0846 0.2302
Schistosoma mansoni ryanodine receptor related 0.0485 0.1001 0.0998
Brugia malayi calpain 5 0.1092 0.233 0.2327
Entamoeba histolytica prefoldin subunit 6, putative 0.0062 0.0074 0.0181
Brugia malayi histone deacetylase 1 (HD1) 0.0086 0.0127 0.0124
Trypanosoma cruzi Aph-1 protein, putative 0.01 0.0157 0.0154
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0103 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0807 0.1707 0.1704
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0015 0.0074
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0159 0.0286 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0079
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.001 0.0006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0016 0.0037
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0135 0.0234 0.0608
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.0127 0.0346
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0235 0.0453 0.0449
Trypanosoma brucei histone deacetylase 2 0.0042 0.0029 0.0061
Schistosoma mansoni cathepsin S (C01 family) 0.0415 0.0846 0.0843
Onchocerca volvulus Neurogenic locus notch homolog 0.0055 0.006 0.0099
Onchocerca volvulus Peroxidase homolog 0.03 0.0596 0.1096
Echinococcus multilocularis orexin receptor type 2 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0415 0.0846 0.23
Loa Loa (eye worm) hypothetical protein 0.0098 0.0153 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0415 0.0846 0.2302
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Brugia malayi Matrixin family protein 0.0053 0.0055 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0789 0.1667 0.3916
Brugia malayi Probable myosin regulatory light chain 0.003 0.0004 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0047 0.0043
Giardia lamblia Alanyl dipeptidyl peptidase 0.0211 0.04 0.1056
Onchocerca volvulus 0.0074 0.0101 0.0176
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0016 0.2276
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0026 0.0071
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0072 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.001 0.0006
Onchocerca volvulus Dual oxidase homolog 0.03 0.0596 0.1096
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0177 0.0325 0.0321
Schistosoma mansoni peroxidasin 0.03 0.0596 0.0592
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.001 0.0006
Onchocerca volvulus 0.0235 0.0453 0.0831
Plasmodium vivax histone deacetylase, putative 0.0097 0.0151 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Trypanosoma brucei cysteine peptidase, putative 0.0807 0.1707 0.4009
Brugia malayi prolyl oligopeptidase family protein 0.0211 0.04 0.0397
Toxoplasma gondii proteasome subunit alpha type, putative 0.0034 0.0013 0.0025
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0015 0.0014
Onchocerca volvulus 0.0074 0.0101 0.0176
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Echinococcus granulosus endothelin converting enzyme 1 0.0098 0.0153 0.015
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.001 0.0006
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.051 0.0506
Echinococcus granulosus EF hand domain containing family member A2 0.0264 0.0517 0.0514
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0084 0.0121 0.0118
Echinococcus granulosus cathepsin L 0.0926 0.1966 0.1963
Toxoplasma gondii calcium-dependent protein kinase 0.0264 0.0517 0.1356
Plasmodium falciparum centrin-1 0.0259 0.0505 0.1369
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Plasmodium vivax unspecified product 0.0511 0.1058 0.2884
Loa Loa (eye worm) blistered cuticle protein 3 0.03 0.0596 0.0596
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0034 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) histone deacetylase 3 0.0086 0.0127 0.0127
Onchocerca volvulus 0.0054 0.0056 0.0091
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1152 0.2462 0.246
Onchocerca volvulus 0.0074 0.0101 0.0176
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Toxoplasma gondii proteasome subunit alpha1, putative 0.0034 0.0013 0.0025
Onchocerca volvulus 0.1676 0.3608 0.6702
Brugia malayi Dopamine receptor protein 2 0.0035 0.0015 0.0011
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0015 0.0011
Plasmodium falciparum peptidase, putative 0.0211 0.04 0.1077
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0556 0.1156 0.1152
Brugia malayi Cathepsin L-like precursor 0.1676 0.3608 0.3606
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.001 0.0006
Toxoplasma gondii EFHC1, putative 0.0259 0.0505 0.1325
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0015 0.0011
Toxoplasma gondii calmodulin CAM1 0.0264 0.0517 0.1356
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Loa Loa (eye worm) hypothetical protein 0.0259 0.0505 0.0505
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0026 0.0071
Trypanosoma brucei small myristoylated protein 1-1 0.0363 0.0734 0.172
Giardia lamblia Cysteine protease 0.0415 0.0846 0.2274
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trypanosoma brucei histone deacetylase, putative 0.0097 0.0151 0.0346
Schistosoma mansoni cathepsin D (A01 family) 0.0707 0.1488 0.1485
Loa Loa (eye worm) hypothetical protein 0.0261 0.051 0.051
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0034 0.0013 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0415 0.0846 0.2302
Brugia malayi nuclear receptor NHR-88 0.0033 0.001 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.01 0.0096
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0234 0.045 0.1342
Toxoplasma gondii proteasome subunit 0.0034 0.0013 0.0025
Brugia malayi Cathepsin L-like precursor 0.1676 0.3608 0.3606
Toxoplasma gondii hypothetical protein 0.0211 0.04 0.1047
Brugia malayi Papain family cysteine protease containing protein 0.0926 0.1966 0.1963
Echinococcus multilocularis G protein coupled receptor 139 0.0035 0.0015 0.0011
Plasmodium falciparum plasmepsin V 0.0093 0.0142 0.0358
Leishmania major proteasome alpha 1 subunit, putative 0.0034 0.0013 0.0022
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0034 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0183 0.0339 0.0339
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0415 0.0846 0.0843
Echinococcus granulosus histone deacetylase 1 0.0086 0.0127 0.0124
Echinococcus granulosus subfamily T1A non peptidase ue 0.0034 0.0013 0.0009
Onchocerca volvulus 0.0035 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Schistosoma mansoni Nep2 peptidase (M13 family) 0.005 0.0047 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0341 0.0686 0.1606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0415 0.0846 0.2302
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0072 0.0072
Trypanosoma brucei protein I/6 0.0259 0.0505 0.1181
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.001 0.0006
Brugia malayi proteasome subunit beta type 1 0.0135 0.0234 0.0231
Schistosoma mansoni opsin-like receptor 0.0035 0.0015 0.0011
Onchocerca volvulus 0.0055 0.006 0.0099
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0259 0.0505 0.1374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1164 0.2489 0.6767
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0717 0.1509 0.4527
Loa Loa (eye worm) hypothetical protein 0.0092 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Schistosoma mansoni hypothetical protein 0.0137 0.0238 0.0235
Onchocerca volvulus 0.0074 0.0101 0.0176
Brugia malayi Peptidase family M13 containing protein 0.0098 0.0153 0.015
Loa Loa (eye worm) hypothetical protein 0.0235 0.0453 0.0453
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0306 0.0609 0.1599
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Echinococcus granulosus centrin 2 0.0259 0.0505 0.0502
Brugia malayi larval opioid receptor 0.0035 0.0015 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0084 0.0121 0.0277
Echinococcus granulosus FTZ F1 alpha 0.0033 0.001 0.0006
Leishmania major small myristoylated protein-2 0.0662 0.1389 0.3261
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0098 0.0153 0.015
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0032 0.0087
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Trypanosoma cruzi cysteine peptidase, putative 0.1969 0.4251 0.4249
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0954 0.2027 0.2024
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.001 0.0006
Echinococcus multilocularis programmed cell death protein 6 0.003 0.0004 0.0001
Echinococcus multilocularis calbindin 32 0.0264 0.0517 0.0514
Onchocerca volvulus 0.0074 0.0101 0.0176
Entamoeba histolytica grainin, putative 0.0264 0.0517 0.1412
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0085 0.0084
Trypanosoma cruzi kinesin, putative 0.1092 0.233 0.2327
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0789 0.1667 0.1664
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0015 0.0011
Toxoplasma gondii centrin, putative 0.0259 0.0505 0.1325
Schistosoma mansoni hypothetical protein 0.0259 0.0505 0.0502
Brugia malayi Animal haem peroxidase family protein 0.03 0.0596 0.0593
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus multilocularis neurogenic locus notch protein 4 0.0054 0.0056 0.0052
Trypanosoma cruzi major cysteine proteinase, putative 0.0415 0.0846 0.0843
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0034 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0062 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0807 0.1707 0.1704
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0034 0.0013 0.0013
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0013 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Plasmodium falciparum histone deacetylase 2 0.0097 0.0151 0.0383
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Echinococcus granulosus neuronal calcium sensor 0.0259 0.0505 0.0502
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0029 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.033 0.0661 0.0657
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Mycobacterium tuberculosis Hypothetical protein 0.0035 0.0015 0.0034
Brugia malayi calpain D 0.0597 0.1245 0.1242
Toxoplasma gondii EGF family domain-containing protein 0.0054 0.0056 0.0137
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0259 0.0505 0.0502
Brugia malayi Cytochrome P450 family protein 0.0091 0.0137 0.0134
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Leishmania major hypothetical protein, conserved 0.0185 0.0343 0.0799
Plasmodium vivax vivapain-2 0.1676 0.3608 0.9922
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0016 0.0033
Leishmania major proteasome beta 5 subunit, putative 0.0174 0.0319 0.0742
Leishmania major calpain protease-like protein 0.0597 0.1245 0.2923
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0029 0.0025
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0034 0.0013 0.0022
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0034 0.0013 0.0011
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0306 0.0609 0.0606
Loa Loa (eye worm) hypothetical protein 0.0415 0.0846 0.0846
Echinococcus granulosus prolyl endopeptidase 0.1759 0.3791 0.3789
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0415 0.0846 0.0843
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0034 0.0013 0.0022
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0415 0.0846 0.23
Plasmodium falciparum glutathione reductase 0.0036 0.0016 0.0008
Brugia malayi Histone deacetylase family protein 0.0097 0.0151 0.0147
Onchocerca volvulus 0.0054 0.0056 0.0091
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0009 0.0013
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0015 0.0014
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0034 0.0013 0.0009
Brugia malayi proteasome subunit beta type 2 0.0084 0.0121 0.0118
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0006
Echinococcus granulosus glycogen phosphorylase 0.0113 0.0187 0.0183
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Leishmania major programmed cell death 6 protein-like protein 0.0259 0.0505 0.1181
Trichomonas vaginalis calmodulin, putative 0.0264 0.0517 0.1407
Brugia malayi cation channel family protein 0.0209 0.0396 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.04 0.1088
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1152 0.2462 0.246
Onchocerca volvulus 0.1251 0.2677 0.497
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0034 0.0013 0.0013
Brugia malayi follicle stimulating hormone receptor 0.0035 0.0015 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.033 0.0661 0.0658
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0084 0.0121 0.0118
Leishmania major hypothetical protein, conserved 0.0211 0.04 0.0932
Toxoplasma gondii calcium binding egf domain-containing protein 0.0053 0.0055 0.0137
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0174 0.0319 0.0948
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) PAN domain-containing protein 0.0074 0.0101 0.0101
Loa Loa (eye worm) ctsf protein 0.1676 0.3608 0.3608
Trypanosoma cruzi histone deacetylase, putative 0.0097 0.0151 0.0147
Leishmania major trypanothione reductase 0.0102 0.0163 0.0374
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0025 0.0035
Trypanosoma brucei prolyl oligopeptidase, putative 0.0717 0.1509 0.3545
Leishmania major hypothetical protein, conserved 0.0121 0.0203 0.0469
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0026 0.0053
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0034 0.0013 0.0009
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4173 0.9079 0.9079
Echinococcus granulosus g protein coupled receptor 0.0035 0.0015 0.0011
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0034 0.0013 0.0009
Onchocerca volvulus 0.0074 0.01 0.0173
Entamoeba histolytica prolyl oligopeptidase family protein 0.0211 0.04 0.1086
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0135 0.0234 0.0541
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0029 0.0025
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0015 0.0011
Entamoeba histolytica cysteine protease, putative 0.0415 0.0846 0.2326
Brugia malayi hypothetical protein 0.0041 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0034 0.0013 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Echinococcus granulosus Mastin 0.0235 0.0453 0.0449
Echinococcus multilocularis glycogen phosphorylase 0.0113 0.0187 0.0183
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0009 0.0005
Echinococcus granulosus neuropeptide receptor A26 0.0035 0.0015 0.0011
Echinococcus multilocularis notch 0.0054 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0086 0.0127 0.0127
Leishmania major histone deacetylase, putative 0.0086 0.0127 0.0291
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0015 0.0011
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0211 0.04 0.1086
Brugia malayi hypothetical protein 0.0096 0.0148 0.0144
Echinococcus granulosus expressed protein 0.0806 0.1704 0.1701
Echinococcus granulosus cpg binding protein 0.0066 0.0084 0.008
Onchocerca volvulus 0.0053 0.0055 0.009
Trypanosoma brucei centrin, putative 0.0259 0.0505 0.1181
Loa Loa (eye worm) cathepsin B 0.1707 0.3677 0.3677
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1676 0.3608 0.9812
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0029 0.0042
Echinococcus multilocularis Transglutaminase 0.0035 0.0015 0.0011
Trichomonas vaginalis calpain, putative 0.0597 0.1245 0.3386
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.3577 0.7772 0.7772
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0046 0.0101
Onchocerca volvulus 0.0049 0.0045 0.0071
Echinococcus multilocularis Tolloid protein 1 0.0084 0.0122 0.0119
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0034 0.0013 0.0028
Echinococcus granulosus calumenin 0.0264 0.0517 0.0514
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0029 0.0025
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Trypanosoma brucei mitochondrial calcium uptake 1 0.0259 0.0505 0.1181
Loa Loa (eye worm) hypothetical protein 0.0054 0.0057 0.0057
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0211 0.04 0.0932
Brugia malayi Kringle domain containing protein 0.0185 0.0343 0.034
Echinococcus multilocularis chromobox protein 1 0.0071 0.0094 0.009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0016 0.0012
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Plasmodium falciparum plasmepsin II 0.024 0.0463 0.1253
Echinococcus multilocularis inhibitor of apoptosis protein 0.0183 0.0339 0.0335
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0035 0.0015 0.0011
Onchocerca volvulus 0.0035 0.0015 0.0015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Schistosoma mansoni hypothetical protein 0.0129 0.022 0.0217
Schistosoma mansoni amine GPCR 0.0035 0.0015 0.0011
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0511 0.1058 0.1058
Brugia malayi Trypsin family protein 0.0235 0.0453 0.045
Brugia malayi Heterochromatin protein 1 0.0071 0.0094 0.0091
Schistosoma mansoni centrin 0.0259 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0084 0.0121 0.033
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0029 0.0026
Brugia malayi Trypsin family protein 0.0406 0.0827 0.0824
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Schistosoma mansoni hypothetical protein 0.0183 0.0339 0.0335
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0034 0.0013 0.0025
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1956 0.4221 0.993
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0034 0.0013 0.0009
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0042 0.0029 0.0029
Entamoeba histolytica hypothetical protein 0.0041 0.0029 0.0055
Echinococcus granulosus cathepsin l1 0.1164 0.2489 0.2486
Echinococcus multilocularis cathepsin b 0.4594 1 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.0163 0.0159
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Onchocerca volvulus 0.2485 0.5381 1
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.008 0.0114 0.011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0211 0.04 0.1088
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0032 0.0087
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.01 0.0272
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0292 0.0288
Toxoplasma gondii prefoldin subunit 6, putative 0.0062 0.0074 0.0187
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Schistosoma mansoni cathepsin F (C01 family) 0.1676 0.3608 0.3606
Mycobacterium tuberculosis Conserved protein 0.0074 0.01 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.001 0.0006
Leishmania major protein kinase, putative 0.0259 0.0505 0.1181
Onchocerca volvulus 0.1676 0.3608 0.6702
Onchocerca volvulus 0.0171 0.0312 0.0568
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0035 0.0015 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.01 0.0096
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0135 0.0234 0.0636
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.0661 0.0657
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trypanosoma cruzi I/6 autoantigen, putative 0.0259 0.0505 0.0502
Leishmania major proteasome alpha 2 subunit, putative 0.0034 0.0013 0.0022
Leishmania major proteasome beta-1 subunit, putative 0.0034 0.0013 0.0022
Trypanosoma brucei calpain, putative 0.0864 0.183 0.43
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0034 0.0013 0.0011
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Echinococcus multilocularis microtubule associated protein 2 0.1507 0.324 0.3238
Trypanosoma brucei proteasome beta 6 subunit 0.0135 0.0234 0.0542
Trichomonas vaginalis set domain proteins, putative 0.125 0.2677 0.7278
Echinococcus granulosus neurogenic locus notch protein 4 0.0054 0.0056 0.0052
Onchocerca volvulus 0.0035 0.0015 0.0015
Loa Loa (eye worm) animal heme peroxidase 0.03 0.0596 0.0596
Echinococcus granulosus peptide allatostatin:somatostatin 0.0035 0.0015 0.0011
Trypanosoma brucei Calpain-like protein 1.1 0.1152 0.2462 0.5789
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Plasmodium vivax vivapain-1 0.0926 0.1966 0.539
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0029 0.0025
Echinococcus granulosus neurogenic locus protein delta 0.0054 0.0056 0.0052
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0015 0.0074
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0259 0.0505 0.0502
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0139 0.0243 0.0239
Brugia malayi Proteasome A-type and B-type family protein 0.0174 0.0319 0.0316
Echinococcus granulosus prefoldin subunit 6 0.0062 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0324 0.0649 0.0649
Trypanosoma brucei oligopeptidase b 0.0717 0.1509 0.3545
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0015 0.0014
Echinococcus multilocularis programmed cell death protein 0.0284 0.056 0.0556
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0415 0.0846 0.2302
Plasmodium vivax calpain, putative 0.1688 0.3637 1
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Brugia malayi Proteasome A-type and B-type family protein 0.0034 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.005 0.0049
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0051 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Brugia malayi hypothetical protein 0.0093 0.0142 0.0138
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.04 0.0396
Trypanosoma brucei calpain-like protein, putative 0.1688 0.3637 0.8553
Loa Loa (eye worm) hypothetical protein 0.0093 0.0142 0.0142
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0034 0.0013 0.0009
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0211 0.04 0.0932
Toxoplasma gondii histone deacetylase HDAC1 0.0097 0.0151 0.0388
Echinococcus multilocularis ryanodine receptor 44f 0.0305 0.0606 0.0603
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Plasmodium vivax unspecified product 0.0415 0.0846 0.23
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.04 0.0397
Brugia malayi Papain family cysteine protease containing protein 0.1676 0.3608 0.3606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1152 0.2462 0.246
Mycobacterium leprae conserved hypothetical protein 0.0074 0.01 0.0639
Echinococcus multilocularis cathepsin b 0.4594 1 1
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0034 0.0013 0.0009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0035 0.0015 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Onchocerca volvulus Matrilysin homolog 0.0049 0.0046 0.0072
Schistosoma mansoni mitochondrial solute carrier 0.0259 0.0505 0.0502
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0032 0.0047
Trichomonas vaginalis calmodulin-2, putative 0.0259 0.0505 0.1374
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.005 0.0046
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.001 0.001
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Leishmania major i/6 autoantigen-like protein 0.0259 0.0505 0.1181
Toxoplasma gondii centrin 0.0259 0.0505 0.1325
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0159 0.0286 0.0282
Trypanosoma cruzi cytochrome P450, putative 0.0067 0.0085 0.0081
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1676 0.3608 0.3606
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Plasmodium falciparum thioredoxin reductase 0.0036 0.0016 0.0008
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0174 0.0319 0.0861
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.001 0.0006
Leishmania major calcineurin B subunit, putative 0.0259 0.0505 0.1181
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0259 0.0505 0.0502
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0152 0.027 0.0267
Toxoplasma gondii preprocathepsin c precursor, putative 0.0415 0.0846 0.2225
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0034 0.0013 0.0011
Brugia malayi nuclear hormone receptor 0.0033 0.001 0.0006
Echinococcus multilocularis calpain A 0.4438 0.9658 0.9658
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0035 0.0015 0.0011
Echinococcus multilocularis lamin dm0 0.0055 0.006 0.0056
Mycobacterium ulcerans putative transglutaminase-like protein 0.0035 0.0015 0.0074
Leishmania major centrin, putative 0.0259 0.0505 0.1181
Brugia malayi Cathepsin L-like precursor 0.1164 0.2489 0.2486
Schistosoma mansoni intermediate filament proteins 0.0055 0.006 0.0056
Brugia malayi calpain family protein 1 0.4173 0.9079 0.9079
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0088 0.0131 0.0131
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0029 0.0025
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0049 0.0046 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0415 0.0846 0.2302
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0029 0.0025
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0034 0.0013 0.0011
Schistosoma mansoni coup transcription factor 0.0033 0.001 0.0006
Trypanosoma cruzi histone deacetylase 1, putative 0.0086 0.0127 0.0124
Giardia lamblia Proteasome subunit beta type 1 0.0135 0.0234 0.0603
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1475 0.3169 0.3167
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0016 0.0029
Brugia malayi Muscle positioning protein 4 0.0055 0.0059 0.0055
Trypanosoma brucei calpain-like protein, putative 0.1956 0.4221 0.993
Schistosoma mansoni hypothetical protein 0.0035 0.0014 0.0011
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Onchocerca volvulus 0.0093 0.0142 0.0251
Echinococcus multilocularis dna polymerase eta 0.0046 0.0039 0.0035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.01 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.033 0.0661 0.0657
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0921 0.1956 0.1953
Echinococcus granulosus histone lysine methyltransferase setb 0.0159 0.0286 0.0282
Echinococcus granulosus glycoprotein Antigen 5 0.0235 0.0453 0.0449
Mycobacterium ulcerans beta-lactamase 0.0074 0.01 0.0639
Trypanosoma cruzi cysteine peptidase, putative 0.1969 0.4251 0.4249
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0292 0.0288
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.01 0.0272
Loa Loa (eye worm) glycogen phosphorylase 0.0113 0.0187 0.0186
Loa Loa (eye worm) hypothetical protein 0.0137 0.0238 0.0238
Loa Loa (eye worm) proteasome subunit beta type 1 0.0135 0.0234 0.0234
Echinococcus multilocularis gamma secretase subunit aph 1 0.0257 0.05 0.0497
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0259 0.0505 0.0502
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0015 0.0011
Schistosoma mansoni hypothetical protein 0.0346 0.0696 0.0693
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.024 0.0463 0.0463
Brugia malayi Papain family cysteine protease containing protein 0.0415 0.0846 0.0843
Entamoeba histolytica calmodulin, putative 0.0259 0.0505 0.1379
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0084 0.0121 0.0311
Trichomonas vaginalis calcineurin B subunit, putative 0.0264 0.0517 0.1407
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1688 0.3637 0.3634
Plasmodium vivax histone deacetylase 2, putative 0.0097 0.0151 0.038
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0415 0.0846 0.0846
Trypanosoma brucei histone deacetylase 3 0.0097 0.0151 0.0346
Loa Loa (eye worm) histone deacetylase 7A 0.0097 0.0151 0.0151
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0034 0.0013 0.0025
Brugia malayi Dopamine receptor 0.0035 0.0015 0.0011
Trypanosoma cruzi histone deacetylase 1, putative 0.0086 0.0127 0.0124
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0029 0.0025
Schistosoma mansoni neuropeptide receptor 0.0035 0.0015 0.0011
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0034 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Brugia malayi calpain 7 0.1688 0.3637 0.3634
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.001 0.0006
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0034 0.0013 0.0009
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Plasmodium falciparum glutathione reductase 0.0102 0.0163 0.0416
Echinococcus multilocularis stromal cell derived factor 2 0.0032 0.0009 0.0005
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0717 0.1509 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0016 0.0029
Schistosoma mansoni rab 0.0259 0.0505 0.0502
Onchocerca volvulus 0.0321 0.0642 0.1182
Onchocerca volvulus 0.03 0.0596 0.1096
Echinococcus multilocularis cysteine protease 0.1676 0.3608 0.3606
Plasmodium falciparum plasmepsin VII 0.0093 0.0142 0.0358
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0034 0.0013 0.0022
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Onchocerca volvulus 0.0055 0.006 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0034 0.0013 0.0025
Onchocerca volvulus 0.0415 0.0846 0.1563
Brugia malayi Trypsin-like protease protein 5 0.0235 0.0453 0.045
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0135 0.0234 0.023
Echinococcus multilocularis calcium uptake protein 1 0.0264 0.0517 0.0514
Onchocerca volvulus 0.0074 0.0101 0.0176
Echinococcus granulosus neuropeptide receptor 0.0035 0.0015 0.0011
Onchocerca volvulus Chorion peroxidase homolog 0.03 0.0596 0.1096
Onchocerca volvulus 0.0035 0.0015 0.0015
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0553 0.115 0.1147
Loa Loa (eye worm) RNA binding protein 0.0061 0.0072 0.0072
Trichomonas vaginalis myosin light chain 1, putative 0.0259 0.0505 0.1374
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0084 0.0122 0.0119
Plasmodium vivax aspartyl protease, putative 0.0172 0.0316 0.0836
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0029 0.0026
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.008 0.0114 0.011
Leishmania major hypothetical protein, conserved 0.0264 0.0517 0.1209
Brugia malayi prolyl oligopeptidase family protein 0.1759 0.3791 0.3789
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0259 0.0505 0.1359
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Echinococcus multilocularis sodium channel protein 0.004 0.0025 0.0022
Brugia malayi Histone deacetylase 1 0.0086 0.0127 0.0124
Echinococcus multilocularis cathepsin L cysteine protease 0.1676 0.3608 0.3606
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.006 0.006
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0174 0.0319 0.0315
Leishmania major hypothetical protein, conserved 0.0211 0.04 0.0932
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0553 0.115 0.1147
Schistosoma mansoni hypothetical protein 0.0185 0.0343 0.034
Brugia malayi hypothetical protein 0.0321 0.0642 0.0639
Brugia malayi Cathepsin L-like precursor 0.1676 0.3608 0.3606
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0926 0.1966 0.1963
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0029 0.0029
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0235 0.0453 0.0449
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0135 0.0234 0.0691
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0415 0.0846 0.0843
Echinococcus granulosus calcium uptake protein 1 0.0264 0.0517 0.0514
Onchocerca volvulus 0.0074 0.0101 0.0176
Echinococcus multilocularis neuropeptide s receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Onchocerca volvulus Notchless protein homolog 0.0034 0.0013 0.0012
Echinococcus granulosus stromal cell derived factor 2 0.0032 0.0009 0.0005
Brugia malayi putative neuropeptide receptor 0.0035 0.0015 0.0011
Schistosoma mansoni histamine h1 receptor 0.0035 0.0015 0.0011
Brugia malayi hypothetical protein 0.0137 0.0238 0.0235
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0016 0.0013
Echinococcus granulosus g protein coupled receptor 0.0035 0.0015 0.0011
Giardia lamblia Hypothetical protein 0.0035 0.0015 0.0005
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0016 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0033 0.001 0.0006
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.024 0.0463 0.126
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1548 0.3329 1
Trypanosoma brucei Calpain-like protein 1.2 0.0954 0.2027 0.4764
Brugia malayi Calcium binding EGF domain containing protein 0.0053 0.0055 0.0052
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0035 0.0015 0.0011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0035 0.0015 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.026 0.0507 0.1514
Echinococcus granulosus proteasome subunit beta type 6 0.0034 0.0013 0.0009
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0385 0.0782 0.0778
Trypanosoma brucei Calpain-like protein 2 0.0936 0.1988 0.4671
Echinococcus granulosus histone deacetylase 6 0.0103 0.0164 0.016
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0807 0.1707 0.1704
Onchocerca volvulus 0.03 0.0596 0.1096
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.375 0.8151 0.8151
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0029 0.0029
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.0127 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0807 0.1707 0.1704
Loa Loa (eye worm) hypothetical protein 0.0073 0.0097 0.0097
Echinococcus multilocularis centrin 2 0.0259 0.0505 0.0502
Loa Loa (eye worm) hypothetical protein 0.0211 0.04 0.04
Schistosoma mansoni neuronal calcium sensor 0.0259 0.0505 0.0502
Loa Loa (eye worm) proteasome subunit beta type 2 0.0084 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Leishmania major cathepsin L-like protease 0.1969 0.4251 1
Loa Loa (eye worm) hypothetical protein 0.0415 0.0846 0.0846
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0015 0.0011
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0211 0.04 0.0932
Echinococcus granulosus calpain 0.1688 0.3637 0.3634
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.01
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0016 0.0029
Brugia malayi Pepsin A precursor 0.0093 0.0142 0.0138
Echinococcus multilocularis EF hand domain containing family member A2 0.0264 0.0517 0.0514
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Leishmania major calpain family cysteine protease-like protein 0.0807 0.1707 0.4009
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0034 0.0013 0.0009
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.024 0.0463 0.046
Plasmodium falciparum cysteine proteinase falcipain 1 0.0926 0.1966 0.5432
Entamoeba histolytica calcium-binding protein, putative 0.0259 0.0505 0.1379
Brugia malayi Blistered cuticle protein 3 0.03 0.0596 0.0593
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0055 0.0052
Onchocerca volvulus 0.0185 0.0343 0.0626
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0308 0.0613 0.1433
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Loa Loa (eye worm) animal heme peroxidase 0.03 0.0596 0.0596
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0415 0.0846 0.23
Brugia malayi Protein kinase domain containing protein 0.0185 0.0343 0.034
Echinococcus granulosus tumor protein p63 0.0369 0.0746 0.0743
Mycobacterium tuberculosis Probable reductase 0.0234 0.045 0.1342
Echinococcus granulosus neuropeptide receptor 0.0035 0.0015 0.0011
Mycobacterium tuberculosis Probable dehydrogenase 0.0234 0.045 0.1342
Trichomonas vaginalis calpain, putative 0.0597 0.1245 0.3386
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0415 0.0846 0.0843
Leishmania major proteasome beta 3 subunit, putative 0.0034 0.0013 0.0022
Trypanosoma cruzi small myristoylated protein 1-2 0.0363 0.0734 0.0731
Schistosoma mansoni calmodulin related calcium binding protein 0.0259 0.0505 0.0502
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0016 0.0012
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0057 0.0053
Brugia malayi Cathepsin L-like precursor 0.1676 0.3608 0.3606
Echinococcus multilocularis histone deacetylase 6 0.0103 0.0164 0.016
Echinococcus granulosus allatostatin A receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0415 0.0846 0.0843
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.4432 0.9646 0.9646
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0006
Loa Loa (eye worm) CYP4Cod1 0.0067 0.0085 0.0084
Giardia lamblia Alanyl dipeptidyl peptidase 0.0211 0.04 0.1056
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0682 0.1432 0.1428
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.01 0.0639
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0259 0.0505 0.1374
Trypanosoma brucei kinesin, putative 0.1092 0.233 0.5476
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0029 0.0029
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0029 0.0025
Onchocerca volvulus 0.0235 0.0453 0.0831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.001 0.0006
Schistosoma mansoni memapsin-2 (A01 family) 0.0956 0.2033 0.203
Leishmania major hypothetical protein, conserved 0.0341 0.0686 0.1606
Onchocerca volvulus 0.017 0.0311 0.0567
Echinococcus multilocularis dnaJ subfamily B 0.0456 0.0938 0.0934
Loa Loa (eye worm) hypothetical protein 0.0049 0.0045 0.0045
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0807 0.1707 0.1704
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trypanosoma cruzi unspecified product 0.0363 0.0734 0.0731
Brugia malayi hypothetical protein 0.0235 0.0453 0.045
Echinococcus multilocularis geminin 0.0346 0.0696 0.0693
Trypanosoma cruzi oligopeptidase b 0.0717 0.1509 0.1506
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0135 0.0234 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0415 0.0846 0.2302
Schistosoma mansoni chromobox protein 0.0071 0.0094 0.009
Brugia malayi cathepsin F-like cysteine proteinase 0.0415 0.0846 0.0843
Echinococcus granulosus peroxidasin 0.03 0.0596 0.0592
Echinococcus granulosus enteropeptidase 0.0235 0.0453 0.0449
Trypanosoma cruzi cysteine peptidase, putative 0.1676 0.3608 0.3606
Echinococcus granulosus slit 2 protein 0.0054 0.0056 0.0052
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0415 0.0846 0.23
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0034 0.0013 0.0025
Brugia malayi fibroinase precursor 0.0415 0.0846 0.0843
Onchocerca volvulus 0.1676 0.3608 0.6702
Toxoplasma gondii microneme protein MIC4 0.0074 0.0101 0.0257
Schistosoma mansoni amine GPCR 0.0035 0.0015 0.0011
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0926 0.1966 0.1963
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0034 0.0013 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.001 0.0006
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0185 0.0343 0.0911
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Schistosoma mansoni caspase-7 (C14 family) 0.0155 0.0277 0.0273
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0553 0.115 0.2128
Schistosoma mansoni hypothetical protein 0.0597 0.1245 0.1242
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0034 0.0013 0.0009
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0034 0.0013 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0035 0.0015 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Echinococcus multilocularis cathepsin L 0.0926 0.1966 0.1963
Echinococcus multilocularis calpain 5 0.1688 0.3637 0.3634
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1759 0.3791 0.3789
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0016 0.0012
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0016 0.0012
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0056 0.006 0.0057
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0034 0.0013 0.0011
Echinococcus granulosus proteasome prosome macropain 0.0174 0.0319 0.0315
Loa Loa (eye worm) hypothetical protein 0.0051 0.0051 0.0051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1152 0.2462 0.5789
Loa Loa (eye worm) programmed cell death protein 6 0.0264 0.0517 0.0517
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0135 0.0234 0.023
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0183 0.0339 0.0336
Echinococcus multilocularis calpain 7 (C02 family) 0.1688 0.3637 0.3634
Brugia malayi Cathepsin L-like precursor 0.0511 0.1058 0.1055
Echinococcus granulosus programmed cell death protein 0.0284 0.056 0.0556
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0009
Plasmodium vivax plasmepsin V, putative 0.0093 0.0142 0.0355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0084 0.0121 0.0118
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0076 0.0076
Plasmodium vivax serine-repeat antigen (SERA) 0.0415 0.0846 0.23
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.01 0.0289
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0235 0.0453 0.0449
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trypanosoma cruzi calmodulin, putative 0.0259 0.0505 0.0502
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1688 0.3637 0.3634
Echinococcus granulosus dro:myosuppressin receptor 0.0035 0.0015 0.0011
Entamoeba histolytica cysteine proteinase 1, putative 0.0926 0.1966 0.5437
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0016 0.0008
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0034 0.0013 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.04 0.0396
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0094 0.0255
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Echinococcus granulosus dnaJ subfamily B 0.0456 0.0938 0.0934
Echinococcus multilocularis transmembrane protease serine 3 0.0235 0.0453 0.0449
Brugia malayi beta-lactamase family protein 0.0074 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.001 0.0006
Echinococcus multilocularis fibropellin Ia 0.0054 0.0056 0.0052
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0174 0.0319 0.0315
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Brugia malayi steroid hormone receptor 0.0033 0.001 0.0006
Schistosoma mansoni histone deacetylase 0.0086 0.0127 0.0124
Onchocerca volvulus 0.0235 0.0453 0.0831
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0035 0.0015 0.0014
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0015 0.0011
Onchocerca volvulus 0.0235 0.0453 0.0831
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0035 0.0015 0.0011
Brugia malayi hypothetical protein 0.03 0.0596 0.0593
Echinococcus granulosus cathepsin l1 0.1676 0.3608 0.3606
Toxoplasma gondii PAN domain-containing protein 0.0074 0.0101 0.0257
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0084 0.0121 0.0118
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0029 0.0025
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1956 0.4221 0.4219
Onchocerca volvulus 0.0074 0.0101 0.0176
Entamoeba histolytica glycogen phosphorylase, putative 0.0113 0.0187 0.0493
Echinococcus multilocularis fat cadherin tumor suppressor 0.0054 0.0056 0.0052
Echinococcus multilocularis musashi 0.0055 0.006 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.017 0.0311 0.0308
Trichomonas vaginalis calcium binding protein, putative 0.0259 0.0505 0.1374
Schistosoma mansoni amine GPCR 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0061 0.0073 0.0073
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0026 0.0149
Toxoplasma gondii proteasome subunit beta type, putative 0.0174 0.0319 0.0832
Echinococcus granulosus EF hand domain containing family member A2 0.0259 0.0505 0.0502
Giardia lamblia Cathepsin B precursor 0.1707 0.3677 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1676 0.3608 0.9812
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0029 0.0026
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0052 0.0052 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0006
Toxoplasma gondii cathepsin CPC2 0.0415 0.0846 0.2225
Leishmania major hypothetical protein, unknown function 0.0597 0.1245 0.2923
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0717 0.1509 0.1506
Schistosoma mansoni cathepsin s 0.0511 0.1058 0.1055
Schistosoma mansoni histone deacetylase hda2 0.0103 0.0164 0.016
Onchocerca volvulus 0.03 0.0596 0.1096
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1048 0.2234 0.5251
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0148 0.0262 0.0258
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Echinococcus granulosus neurogenic locus notch protein 0.0054 0.0056 0.0052
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0211 0.04 0.0932
Echinococcus multilocularis neurogenic locus notch protein 0.0055 0.0059 0.0055
Brugia malayi cathepsin L-like precursor 0.1164 0.2489 0.2486
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.001 0.0006
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0016 0.0008
Mycobacterium ulcerans transglutaminase family protein 0.0035 0.0015 0.0074
Loa Loa (eye worm) calpain 0.1688 0.3637 0.3636
Leishmania major oligopeptidase b 0.0717 0.1509 0.3545
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.001 0.001
Onchocerca volvulus 0.0054 0.0057 0.0093
Toxoplasma gondii histone deacetylase HDAC2 0.0086 0.0127 0.0327
Loa Loa (eye worm) hypothetical protein 0.1164 0.2489 0.2489
Echinococcus multilocularis neuropeptide FF receptor 2 0.0035 0.0015 0.0011
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0597 0.1245 0.3278
Giardia lamblia Hypothetical protein 0.0062 0.0074 0.0167
Trypanosoma brucei prolyl endopeptidase 0.1759 0.3791 0.8917
Onchocerca volvulus 0.0074 0.01 0.0173
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Brugia malayi hypothetical protein 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0406 0.0827 0.0826
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0159 0.0286 0.0282
Echinococcus granulosus proteasome subunit alpha type 2 0.0034 0.0013 0.0009
Schistosoma mansoni cpg binding protein 0.0066 0.0084 0.008
Echinococcus multilocularis slit 2 protein 0.0054 0.0056 0.0052
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.001 0.0006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0035 0.0015 0.0011
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.001 0.0006
Trypanosoma brucei caltractin, putative 0.0284 0.056 0.1309
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0234 0.045 0.2965
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0034 0.0013 0.0009
Giardia lamblia Cysteine protease 0.0415 0.0846 0.2274
Echinococcus granulosus cathepsin L cysteine proteinase 0.1676 0.3608 0.3606
Brugia malayi Cathepsin L-like cysteine proteinase 0.1164 0.2489 0.2486
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0026 0.0053
Toxoplasma gondii PAN domain-containing protein 0.0074 0.0101 0.0257
Loa Loa (eye worm) hypothetical protein 0.1759 0.3791 0.3791
Giardia lamblia Cathepsin B precursor 0.0415 0.0846 0.2274
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0034 0.0013 0.0009
Echinococcus granulosus protein jagged 1 0.0054 0.0056 0.0052
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0098 0.0153 0.045
Leishmania major cathepsin L-like protease 0.1676 0.3608 0.8486
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0015 0.0011
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0415 0.0846 0.2318
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0053 0.0055 0.0055
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0015 0.0011
Echinococcus granulosus neurogenic locus notch protein 0.0055 0.0059 0.0055
Leishmania major cytochrome p450-like protein 0.0067 0.0085 0.019
Echinococcus multilocularis enteropeptidase 0.0235 0.0453 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0079
Loa Loa (eye worm) hypothetical protein 0.0511 0.1058 0.1058
Schistosoma mansoni septate junction protein 0.0054 0.0056 0.0052
Plasmodium falciparum plasmepsin I 0.024 0.0463 0.1253
Plasmodium vivax histone deacetylase, putative 0.0042 0.0029 0.0045
Schistosoma mansoni calpain-7 (C02 family) 0.1691 0.3643 0.3641
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0415 0.0846 0.23
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.001 0.0006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0954 0.2027 0.4764
Echinococcus granulosus orexin receptor type 2 0.0035 0.0015 0.0011
Brugia malayi MH2 domain containing protein 0.0368 0.0744 0.0741
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.001 0.0006
Giardia lamblia Hypothetical protein 0.0264 0.0517 0.1376
Loa Loa (eye worm) hypothetical protein 0.0185 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0597 0.1245 0.3386
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0016 0.0082
Loa Loa (eye worm) hypothetical protein 0.0259 0.0505 0.0505
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0039 0.0035
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus multilocularis somatostatin receptor 0.0035 0.0015 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0267 0.0523 0.1223
Trypanosoma brucei proteasome beta 7 subunit 0.0034 0.0013 0.0022
Schistosoma mansoni biogenic amine receptor 0.0035 0.0015 0.0011
Entamoeba histolytica cysteine protease, putative 0.0415 0.0846 0.2326
Echinococcus granulosus glycogen phosphorylase 0.0113 0.0187 0.0183
Trypanosoma cruzi kinesin, putative 0.1092 0.233 0.2327
Echinococcus multilocularis neuropeptide receptor A26 0.0035 0.0015 0.0011
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1759 0.3791 0.3789
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0415 0.0846 0.0843
Toxoplasma gondii PAN domain-containing protein 0.0074 0.0101 0.0257
Mycobacterium ulcerans hypothetical protein 0.0074 0.01 0.0639
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Echinococcus multilocularis neurocalcin 0.0259 0.0505 0.0502
Schistosoma mansoni histone deacetylase 4 5 0.0097 0.0151 0.0147
Onchocerca volvulus Deterin homolog 0.0183 0.0339 0.0618
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Toxoplasma gondii aspartyl protease 0.0093 0.0142 0.0364
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Trypanosoma brucei antigen, putative 0.1688 0.3637 0.8553
Loa Loa (eye worm) hypothetical protein 0.0074 0.01 0.01
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Toxoplasma gondii troponin c, isotype gamma, putative 0.0259 0.0505 0.1325
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0011
Trypanosoma brucei calmodulin, putative 0.0264 0.0517 0.1209
Brugia malayi cathepsin L precursor 0.0415 0.0846 0.0843
Brugia malayi Papain family cysteine protease containing protein 0.0415 0.0846 0.0843
Echinococcus granulosus neural cadherin 0.0054 0.0056 0.0052
Loa Loa (eye worm) cytochrome P450 0.003 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0926 0.1966 0.5346
Loa Loa (eye worm) MIR domain-containing protein 0.0032 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0072 0.0069
Leishmania major proteasome alpha 1 subunit, putative 0.0034 0.0013 0.0022
Echinococcus multilocularis histone deacetylase 6 0.0097 0.0151 0.0147
Loa Loa (eye worm) myosin Light Chain family member 0.003 0.0004 0.0004
Schistosoma mansoni ap endonuclease 0.004 0.0026 0.0022
Brugia malayi G-protein coupled receptor 0.0035 0.0015 0.0011
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0034 0.0013 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1152 0.2462 0.5789
Entamoeba histolytica calpain family cysteine protease, putative 0.0597 0.1245 0.3434
Leishmania major small myristoylated protein 4, putative 0.0573 0.1193 0.28
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0035 0.0015 0.0011
Loa Loa (eye worm) calmodulin-like protein 0.0259 0.0505 0.0505
Echinococcus granulosus proteasome subunit beta t family 0.0034 0.0013 0.0009
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0485 0.1001 0.0998
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0926 0.1966 0.462
Brugia malayi Cadherin domain containing protein 0.0054 0.0056 0.0052
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0009
Trypanosoma cruzi caltractin, putative 0.0259 0.0505 0.0502
Trypanosoma cruzi centrin, putative 0.0284 0.056 0.0556
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trypanosoma cruzi histone deacetylase, putative 0.0097 0.0151 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0012
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0035 0.0015 0.0011
Schistosoma mansoni notch 0.0054 0.0056 0.0052
Entamoeba histolytica hypothetical protein, conserved 0.0211 0.04 0.1086
Echinococcus multilocularis histone deacetylase 3 0.0086 0.0127 0.0124
Onchocerca volvulus Cathepsin L homolog 0.1676 0.3608 0.6702
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0029 0.0029
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0029 0.0025
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0016 0.0008
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0026 0.0047
Trypanosoma cruzi cysteine peptidase, putative 0.0511 0.1058 0.1055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.001 0.0006
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0174 0.0319 0.0835
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0211 0.04 0.1086
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0035 0.0015 0.0011
Brugia malayi intermediate filament protein 0.0055 0.006 0.0056
Brugia malayi beta-lactamase family protein 0.0074 0.01 0.0097
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0415 0.0846 0.2326
Brugia malayi Muscleblind-like protein 0.0151 0.0269 0.0266
Echinococcus granulosus calpain 7 C02 family 0.1688 0.3637 0.3634
Loa Loa (eye worm) TYRA-2 protein 0.0035 0.0015 0.0014
Plasmodium vivax serine-repeat antigen (SERA) 0.0415 0.0846 0.23
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Echinococcus granulosus Proteasome subunit alpha beta 0.0034 0.0013 0.0009
Trichomonas vaginalis calcium binding protein, putative 0.0259 0.0505 0.1374
Schistosoma mansoni cathepsin F (C01 family) 0.1676 0.3608 0.3606
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0415 0.0846 0.0843
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0789 0.1667 0.3916
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Brugia malayi proteasome subunit alpha type 2 0.0034 0.0013 0.001
Plasmodium falciparum serine repeat antigen 1 0.0415 0.0846 0.2318
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0415 0.0846 0.2302
Onchocerca volvulus 0.0074 0.0101 0.0176
Brugia malayi glutathione reductase 0.0102 0.0163 0.0159
Giardia lamblia Cathepsin L precursor 0.0415 0.0846 0.2274
Mycobacterium tuberculosis Conserved protein 0.0074 0.01 0.0289
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0084 0.0121 0.0302
Echinococcus granulosus protein jagged 2 0.0054 0.0056 0.0052
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0035 0.0015 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.01 0.0272
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0034 0.0013 0.0009
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1108 0.2366 0.5562
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.01 0.0289
Schistosoma mansoni peroxidasin 0.03 0.0596 0.0592
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0072 0.0069
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0306 0.0609 0.1426
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0029 0.0029
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0135 0.0234 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1164 0.2489 0.6767
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1757 0.3787 0.3785
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1048 0.2234 0.5251
Loa Loa (eye worm) hypothetical protein 0.4594 1 1
Brugia malayi Calmodulin-like protein 0.0259 0.0505 0.0502
Trypanosoma cruzi prefoldin subunit, putative 0.0062 0.0074 0.0071
Plasmodium vivax histone deacetylase 1, putative 0.0086 0.0127 0.0316
Toxoplasma gondii subtilisin SUB12 0.0074 0.0101 0.0257
Plasmodium vivax aspartyl protease, putative 0.0093 0.0142 0.0355
Echinococcus multilocularis G-protein coupled receptor, putative 0.0035 0.0015 0.0011
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Schistosoma mansoni adenoreceptor 0.0035 0.0015 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0926 0.1966 0.1963
Onchocerca volvulus 0.0035 0.0015 0.0015
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.001 0.0006
Brugia malayi chromobox protein homolog 3 0.004 0.0025 0.0022
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0003 0.0003
Loa Loa (eye worm) prolyl oligopeptidase 0.0211 0.04 0.04
Schistosoma mansoni hypothetical protein 0.0062 0.0074 0.0071
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0183 0.0339 0.0336
Onchocerca volvulus 0.0137 0.0238 0.0431
Plasmodium falciparum serine repeat antigen 4 0.0415 0.0846 0.2318
Loa Loa (eye worm) hypothetical protein 0.1676 0.3608 0.3608
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0415 0.0846 0.23
Toxoplasma gondii prolyl endopeptidase 0.1759 0.3791 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Brugia malayi G protein-coupled receptor F59B2.13 0.0035 0.0015 0.0011
Echinococcus multilocularis lamin 0.0055 0.006 0.0056
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0686 0.0682
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0415 0.0846 0.2274
Onchocerca volvulus 0.0032 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0026 0.0023
Toxoplasma gondii thioredoxin reductase 0.0102 0.0163 0.042
Brugia malayi hypothetical protein 0.0041 0.0029 0.0026
Echinococcus granulosus calbindin 32 0.0264 0.0517 0.0514
Toxoplasma gondii exonuclease III APE 0.004 0.0026 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.0234 0.023
Loa Loa (eye worm) hypothetical protein 0.0082 0.0118 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0415 0.0846 0.2302
Mycobacterium ulcerans hypothetical protein 0.0035 0.0015 0.0074
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0029 0.0025
Brugia malayi calpain family protein 1 0.4173 0.9079 0.9079
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0026 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Echinococcus granulosus cathepsin L cysteine protease 0.0926 0.1966 0.1963
Leishmania major receptor-type adenylate cyclase a-like protein 0.0211 0.04 0.0932
Toxoplasma gondii ABC1 family protein 0.0074 0.01 0.0254
Toxoplasma gondii proteasome beta subunit 0.0034 0.0013 0.0025
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0015 0.0011
Brugia malayi Proteasome subunit alpha type 1 0.0034 0.0013 0.001
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0597 0.1245 0.3386
Giardia lamblia Hypothetical protein 0.0415 0.0846 0.2274
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0015 0.0011
Trypanosoma brucei histone deacetylase 1 0.0086 0.0127 0.0291
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1688 0.3637 0.8553
Trypanosoma brucei proteasome alpha 7 subunit 0.0034 0.0013 0.0022
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0047 0.0043
Echinococcus multilocularis g-protein coupled receptor 0.0035 0.0015 0.0011
Trypanosoma brucei prefoldin subunit, putative 0.0062 0.0074 0.0166
Trypanosoma brucei calpain-like protein, putative 0.1688 0.3637 0.8553
Plasmodium falciparum serine repeat antigen 3 0.0415 0.0846 0.2318
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0029 0.0025
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0035 0.0015 0.0014
Trypanosoma brucei DNA polymerase eta, putative 0.0046 0.0039 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1245 0.2923
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0079
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0034 0.0013 0.0011
Onchocerca volvulus 0.0035 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Trypanosoma cruzi histone deacetylase, putative 0.0097 0.0151 0.0147
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0093 0.0142 0.0138
Onchocerca volvulus Cathepsin L homolog 0.0415 0.0846 0.1563
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0061 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1969 0.4251 1
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0163 0.0159
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Echinococcus granulosus intermediate filament protein 0.0055 0.006 0.0056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.001 0.0006
Brugia malayi EGF-like domain containing protein 0.0054 0.0056 0.0052
Plasmodium vivax centrin-1, putative 0.0259 0.0505 0.1359
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0174 0.0319 0.0319
Brugia malayi Cytochrome P450 family protein 0.0067 0.0085 0.0081
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0135 0.0234 0.023
Brugia malayi PXA domain containing protein 0.0041 0.0029 0.0026
Schistosoma mansoni ef hand domain family member A2 0.0259 0.0505 0.0502
Onchocerca volvulus 0.0259 0.0505 0.0928
Echinococcus granulosus cysteine protease 0.0926 0.1966 0.1963
Trypanosoma brucei Component of motile flagella 41 0.0259 0.0505 0.1181
Leishmania major calcium channel protein, putative,ion transporter, putative 0.004 0.0025 0.0051
Echinococcus granulosus proteasome subunit alpha type 6 0.0034 0.0013 0.0009
Loa Loa (eye worm) animal heme peroxidase 0.03 0.0596 0.0596
Loa Loa (eye worm) aspartyl protease 6 0.0093 0.0142 0.0142
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0015 0.0011
Onchocerca volvulus 0.0035 0.0015 0.0015
Echinococcus granulosus dna polymerase eta 0.0046 0.0039 0.0035
Brugia malayi Histone deacetylase family protein 0.0097 0.0151 0.0147
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0026 0.0036
Brugia malayi histone deacetylase 11 0.0042 0.0029 0.0026
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0163 0.0163
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0034 0.0013 0.0011
Loa Loa (eye worm) peptidase family M13 containing protein 0.0073 0.0097 0.0097
Brugia malayi TAR-binding protein 0.0061 0.0072 0.0069
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0029 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0259 0.0505 0.1374
Loa Loa (eye worm) hypothetical protein 0.1164 0.2489 0.2489
Toxoplasma gondii cathepsin B 0.1707 0.3677 0.97
Schistosoma mansoni notch 0.0054 0.0056 0.0052
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0267 0.0523 0.1223
Brugia malayi Cathepsin L-like precursor 0.1676 0.3608 0.3606
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0034 0.0013 0.0009
Toxoplasma gondii hypothetical protein 0.0074 0.0101 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0074 0.0202
Loa Loa (eye worm) animal heme peroxidase 0.03 0.0596 0.0596
Schistosoma mansoni calpain-2 (C02 family) 0.0597 0.1245 0.1242
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1759 0.3791 0.8917
Leishmania major cathepsin L-like protease 0.1676 0.3608 0.8486
Echinococcus multilocularis neurogenic locus protein delta 0.0054 0.0056 0.0052
Schistosoma mansoni neuropeptide f receptor 76f 0.0035 0.0015 0.0011
Entamoeba histolytica cysteine protease, putative 0.0415 0.0846 0.2326
Brugia malayi aspartic protease BmAsp-2, identical 0.0093 0.0142 0.0138
Schistosoma mansoni histone deacetylase 0.0086 0.0127 0.0124
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.0127 0.0346
Schistosoma mansoni inhibitor of apoptosis protein 0.0183 0.0339 0.0335
Brugia malayi Animal haem peroxidase family protein 0.03 0.0596 0.0593
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0035 0.0015 0.0011
Brugia malayi GnHR receptor homolog 0.0035 0.0015 0.0011
Echinococcus multilocularis prolyl endopeptidase 0.1759 0.3791 0.3789
Trypanosoma cruzi cysteine peptidase, putative 0.1969 0.4251 0.4249
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.01 0.0096
Plasmodium vivax unspecified product 0.0926 0.1966 0.539
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0094 0.0255
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0239 0.0461 0.0458
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0064
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0259 0.0505 0.1379
Trichomonas vaginalis calcium binding proteins, putative 0.0259 0.0505 0.1374
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0016 0.0029
Onchocerca volvulus 0.0074 0.0101 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.001 0.0006
Onchocerca volvulus Glycogen phosphorylase homolog 0.0113 0.0187 0.0335
Trypanosoma cruzi conserved protein 0.0816 0.1726 0.1723
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0415 0.0846 0.2274
Echinococcus multilocularis fibrillin 1 0.0053 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0098 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0041 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0019
Giardia lamblia Cathepsin L precursor 0.0415 0.0846 0.2274
Echinococcus granulosus lamin dm0 0.0055 0.006 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0034 0.0013 0.0013
Plasmodium falciparum plasmepsin IV 0.024 0.0463 0.1253
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0016 0.0082
Echinococcus granulosus apoptotic protease activating factor 1 0.0137 0.0238 0.0235
Schistosoma mansoni growth hormone secretagogue receptor 0.0035 0.0015 0.0011
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0034 0.0013 0.0009
Trichomonas vaginalis centrin, putative 0.0259 0.0505 0.1374
Trypanosoma brucei cysteine peptidase C (CPC) 0.1707 0.3677 0.8649
Echinococcus multilocularis cpg binding protein 0.0066 0.0084 0.008
Echinococcus granulosus ryanodine receptor 44f 0.0393 0.08 0.0797
Schistosoma mansoni calpain (C02 family) 0.1688 0.3637 0.3634
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0034 0.0013 0.0013
Brugia malayi Animal haem peroxidase family protein 0.03 0.0596 0.0593
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0015 0.0011
Brugia malayi beta-lactamase 0.0074 0.01 0.0097
Echinococcus granulosus fibropellin Ia 0.0054 0.0056 0.0052
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0129 0.022 0.0217
Schistosoma mansoni notch 0.0055 0.006 0.0056
Echinococcus multilocularis proteasome subunit alpha type 2 0.0034 0.0013 0.0009
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1676 0.3608 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.001 0.0006
Echinococcus granulosus acylamino acid releasing enzyme 0.0211 0.04 0.0397
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0264 0.0517 0.0514
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0034 0.0013 0.0013
Echinococcus multilocularis cysteine protease 0.1676 0.3608 0.3606
Onchocerca volvulus 0.0093 0.0142 0.0251
Echinococcus multilocularis acylamino acid releasing enzyme 0.0211 0.04 0.0397
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0029 0.0025
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0308 0.0613 0.0609
Echinococcus multilocularis apoptotic protease activating factor 1 0.0137 0.0238 0.0235
Echinococcus multilocularis calpain family protein 1, d 0.3082 0.6688 0.6687
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0079
Trypanosoma cruzi oligopeptidase b 0.0717 0.1509 0.1506
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Plasmodium falciparum serine repeat antigen 8 0.0415 0.0846 0.2318
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0807 0.1707 0.1704
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.001 0.001
Loa Loa (eye worm) trypsin family protein 0.0235 0.0453 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0597 0.1245 0.3386
Onchocerca volvulus 0.0035 0.0015 0.0015
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0013 0.0022
Entamoeba histolytica cysteine proteinase, putative 0.0926 0.1966 0.5437
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0306 0.0609 0.0606
Toxoplasma gondii peptidase, T1 family protein 0.0034 0.0013 0.0025
Echinococcus multilocularis tissue type plasminogen activator 0.0185 0.0343 0.034
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1956 0.4221 0.4219
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0085 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1881 0.4058 0.9546
Leishmania major centrin, putative,caltractin, putative 0.0259 0.0505 0.1181
Leishmania major hypothetical protein, conserved 0.0816 0.1726 0.4056
Trypanosoma brucei centrin, putative 0.0259 0.0505 0.1181
Leishmania major kinesin, putative 0.1092 0.233 0.5476
Echinococcus multilocularis protein jagged 1 0.0054 0.0056 0.0052
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0016 0.2276
Leishmania major phospholipase c-like protein 0.0259 0.0505 0.1181
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.001 0.0006
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0098 0.0153 0.015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0789 0.1667 0.3916
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0259 0.0505 0.1181
Brugia malayi ORL1-like opioid receptor 0.0035 0.0015 0.0011
Brugia malayi MIR domain containing protein 0.0032 0.0009 0.0006
Echinococcus multilocularis calmodulin 0.0259 0.0505 0.0502
Schistosoma mansoni biogenic amine receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.0235 0.0453 0.0449
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0035 0.0015 0.0011
Trichomonas vaginalis calmodulin, putative 0.0259 0.0505 0.1374
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0084 0.0121 0.0312
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0015 0.0011
Schistosoma mansoni glycogen phosphorylase 0.0049 0.0046 0.0042
Loa Loa (eye worm) hypothetical protein 0.0321 0.0642 0.0642
Brugia malayi 20S proteasome alpha5 subunit 0.0034 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Onchocerca volvulus Peroxidasin homolog 0.03 0.0596 0.1096
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1688 0.3637 0.3634
Entamoeba histolytica cysteine proteinase, putative 0.0926 0.1966 0.5437
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.01 0.0272
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0259 0.0505 0.0502
Onchocerca volvulus Cell death protein 3 homolog 0.0155 0.0277 0.0503
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0034 0.0013 0.0009
Onchocerca volvulus 0.0235 0.0453 0.0831
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0717 0.1509 0.1506
Leishmania major proteasome alpha 7 subunit, putative 0.0034 0.0013 0.0022
Echinococcus multilocularis neural cadherin 0.0054 0.0056 0.0052
Leishmania major proteasome beta 2 subunit, putative 0.0034 0.0013 0.0022
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1035 0.2205 0.2202
Trypanosoma cruzi Aph-1 protein, putative 0.01 0.0157 0.0154
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1099 0.2345 0.2344
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0029 0.0068
Leishmania major hypothetical protein, conserved 0.0211 0.04 0.0932
Schistosoma mansoni cercarial elastase (S01 family) 0.0235 0.0453 0.0449
Brugia malayi Cadherin domain containing protein 0.0054 0.0056 0.0052
Trypanosoma brucei centrin-3 0.0284 0.056 0.1309
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.033 0.0661 0.0657
Trypanosoma brucei I/6 autoantigen 0.0259 0.0505 0.1181
Leishmania major cathepsin L-like protease 0.1676 0.3608 0.8486
Onchocerca volvulus Cathepsin L homolog 0.1676 0.3608 0.6702
Brugia malayi gamma-secretase subunit aph-1 0.0257 0.05 0.0497
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0074 0.0101 0.0257
Trichomonas vaginalis histone deacetylase, putative 0.0086 0.0127 0.0346
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Brugia malayi RNA binding protein 0.0061 0.0072 0.0069
Schistosoma mansoni alpha-1 adrenergic receptor 0.0035 0.0015 0.0011
Echinococcus multilocularis dro:myosuppressin receptor 0.0035 0.0015 0.0011
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0035 0.0015 0.0011
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0016 0.0029
Onchocerca volvulus 0.0406 0.0827 0.1526
Echinococcus multilocularis serotonin receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0012
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0183 0.0339 0.0335
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0415 0.0846 0.0843
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0415 0.0846 0.23
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0012
Plasmodium falciparum serine repeat antigen 9 0.0415 0.0846 0.2318
Echinococcus granulosus gamma secretase subunit aph 1 0.0257 0.05 0.0497
Schistosoma mansoni notch 0.0054 0.0056 0.0052
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0029 0.0025
Loa Loa (eye worm) PAN domain-containing protein 0.0074 0.0101 0.0101
Schistosoma mansoni myosin xvIII 0.0035 0.0015 0.0011
Loa Loa (eye worm) TK/ROR protein kinase 0.0185 0.0343 0.0343
Loa Loa (eye worm) PAN domain-containing protein 0.0074 0.0101 0.0101
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0415 0.0846 0.2274
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1707 0.3677 0.8649
Brugia malayi Papain family cysteine protease containing protein 0.0926 0.1966 0.1963
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1676 0.3608 0.9812
Brugia malayi KE2 family protein 0.0062 0.0074 0.0071
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1956 0.4221 0.993
Echinococcus multilocularis glycoprotein Antigen 5 0.0235 0.0453 0.0449
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0034 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.03 0.0596 0.0596
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0093 0.0142 0.0142
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0235 0.0453 0.0449
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0032 0.0009 0.0005
Leishmania major calmodulin-like protein 0.0259 0.0505 0.1181
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0211 0.04 0.0397
Echinococcus multilocularis proteasome subunit alpha type 6 0.0034 0.0013 0.0009
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0235 0.0453 0.0449
Schistosoma mansoni survival motor neuron protein 0.0053 0.0055 0.0051
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0259 0.0505 0.1379
Brugia malayi Peroxidasin 0.03 0.0596 0.0593
Loa Loa (eye worm) hypothetical protein 0.0415 0.0846 0.0846
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1458 0.3131 0.3129
Schistosoma mansoni glycogen phosphorylase 0.0113 0.0187 0.0183
Brugia malayi Serotonin receptor 0.0035 0.0015 0.0011
Mycobacterium tuberculosis Conserved protein 0.0074 0.01 0.0289
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4432 0.9646 0.9646
Echinococcus multilocularis prefoldin subunit 6 0.0062 0.0074 0.0071
Toxoplasma gondii hypothetical protein 0.0074 0.0101 0.0257
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0511 0.1058 0.1055
Trichomonas vaginalis conserved hypothetical protein 0.0415 0.0846 0.2302
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0034 0.0013 0.0013
Onchocerca volvulus 0.0035 0.0015 0.0015
Giardia lamblia Cathepsin L precursor 0.0415 0.0846 0.2274
Brugia malayi proteasome subunit alpha type 4 0.0034 0.0013 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Echinococcus granulosus calpain 5 0.1688 0.3637 0.3634
Brugia malayi Cell death protein 3 precursor 0.0155 0.0277 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0341 0.0686 0.0682
Plasmodium falciparum plasmepsin III 0.0093 0.0142 0.0358
Loa Loa (eye worm) glutathione reductase 0.0102 0.0163 0.0163
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0015 0.0011
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0051 0.0105
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0012
Trypanosoma brucei unspecified product 0.0211 0.04 0.0932
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0029 0.0025
Loa Loa (eye worm) histone deacetylase 1 0.0086 0.0127 0.0127
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.01 0.0226
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4594 1 1
Giardia lamblia Cathepsin B precursor 0.0415 0.0846 0.2274
Loa Loa (eye worm) MH2 domain-containing protein 0.0368 0.0744 0.0744
Leishmania major cathepsin L-like protease 0.1969 0.4251 1
Toxoplasma gondii cathepsin CPL 0.1676 0.3608 0.9517
Trypanosoma cruzi small myristoylated protein 1-1 0.0363 0.0734 0.0731
Leishmania major hypothetical protein, conserved 0.0211 0.04 0.0932
Plasmodium falciparum plasmepsin X 0.0172 0.0316 0.0842
Entamoeba histolytica protein kinase, putative 0.1092 0.233 0.6447
Onchocerca volvulus 0.1676 0.3608 0.6702
Brugia malayi Fibulin-1 precursor 0.0053 0.0055 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0015 0.0011
Mycobacterium ulcerans hypothetical protein 0.0235 0.0453 0.2984
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0135 0.0234 0.023
Plasmodium falciparum serine repeat antigen 5 0.0415 0.0846 0.2318
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0415 0.0846 0.23
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0086 0.0127 0.0346
Entamoeba histolytica cysteine protease, putative 0.1676 0.3608 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0415 0.0846 0.2302
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0415 0.0846 0.0843
Schistosoma mansoni cathepsin F (C01 family) 0.1164 0.2489 0.2486
Echinococcus granulosus delta-like protein 1 0.0054 0.0056 0.0052
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0264 0.0517 0.0514
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1152 0.2462 0.5789
Brugia malayi neuropeptide F receptor 0.0035 0.0015 0.0011
Schistosoma mansoni hypothetical protein 0.0054 0.0056 0.0052
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0211 0.04 0.1088
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0013 0.0035
Brugia malayi G protein-coupled receptor 0.0035 0.0015 0.0011
Giardia lamblia Cathepsin B precursor 0.0415 0.0846 0.2274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0415 0.0846 0.2302
Loa Loa (eye worm) PAN domain-containing protein 0.0074 0.0101 0.0101
Giardia lamblia Cathepsin L precursor 0.0415 0.0846 0.2274
Toxoplasma gondii histone lysine methyltransferase SET1 0.0125 0.0212 0.0549
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0051 0.0106
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0306 0.0609 0.1426
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0864 0.183 0.43
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Echinococcus granulosus notch 0.0054 0.0056 0.0052
Plasmodium vivax proteasome subunit beta type-1, putative 0.0135 0.0234 0.061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0159 0.0286 0.0282
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0034 0.0013 0.0009
Schistosoma mansoni amine GPCR 0.0035 0.0015 0.0011
Leishmania major cathepsin L-like protease 0.1676 0.3608 0.8486
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1688 0.3637 0.3634
Leishmania major centrin, putative 0.0259 0.0505 0.1181
Toxoplasma gondii hypothetical protein 0.0597 0.1245 0.3278
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0015 0.0011
Echinococcus granulosus calmodulin 0.0259 0.0505 0.0502
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.026 0.0507 0.3344
Echinococcus multilocularis cathepsin L 0.0415 0.0846 0.0843
Giardia lamblia Hypothetical protein 0.0415 0.0846 0.2274
Echinococcus multilocularis serotonin receptor 0.0035 0.0015 0.0011
Loa Loa (eye worm) fibroinase 0.1676 0.3608 0.3608
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0013 0.0035
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0597 0.1245 0.3386
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.001 0.0006
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0074 0.0101 0.0101
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.01 0.0272
Echinococcus granulosus histone deacetylase 6 0.0097 0.0151 0.0147
Schistosoma mansoni cpg binding protein 0.0066 0.0084 0.008
Trypanosoma cruzi cruzipain precursor, putative 0.0511 0.1058 0.1055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Loa Loa (eye worm) intermediate filament protein 0.0055 0.006 0.006
Loa Loa (eye worm) calpain family protein 1 0.3082 0.6688 0.6688
Onchocerca volvulus 0.1164 0.2489 0.4618
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0029 0.0025
Onchocerca volvulus 0.0035 0.0015 0.0015
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.01 0.0289
Loa Loa (eye worm) matrixin family protein 0.0049 0.0046 0.0045
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.4432 0.9646 0.9646
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0029 0.0026
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0055 0.0059 0.0055
Toxoplasma gondii PAN domain-containing protein 0.0074 0.0101 0.0257
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.001 0.0006
Entamoeba histolytica hypothetical protein, conserved 0.0264 0.0517 0.1412
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0026 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0211 0.04 0.0397
Trichomonas vaginalis mannosyltransferase 1, putative 0.0032 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0415 0.0846 0.2302
Brugia malayi PXA domain containing protein 0.0041 0.0029 0.0026
Echinococcus multilocularis proteasome subunit beta type 6 0.0034 0.0013 0.0009
Trichomonas vaginalis centrin, putative 0.0259 0.0505 0.1374
Brugia malayi Trypsin family protein 0.0235 0.0453 0.045
Loa Loa (eye worm) hypothetical protein 0.0096 0.0148 0.0147
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0034 0.0013 0.0011
Mycobacterium ulcerans zinc metalloprotease 0.0098 0.0153 0.0994
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0211 0.04 0.0933
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0159 0.0286 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1676 0.3608 0.9812
Brugia malayi PAN domain containing protein 0.0074 0.0101 0.0098
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0055 0.006 0.006
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0034 0.0013 0.0022
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0034 0.0013 0.0011
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.004 0.0025 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0016 0.0012
Leishmania major histone deacetylase, putative 0.0097 0.0151 0.0346
Schistosoma mansoni hypothetical protein 0.0235 0.0453 0.0449
Loa Loa (eye worm) aspartic protease BmAsp-2 0.024 0.0463 0.0463
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0926 0.1966 0.1963
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0415 0.0846 0.2302
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0034 0.0013 0.0022
Loa Loa (eye worm) peptidase family M13 containing protein 0.0073 0.0097 0.0097
Plasmodium falciparum calpain 0.0597 0.1245 0.3427
Trypanosoma cruzi cysteine proteinase, putative 0.0926 0.1966 0.1963
Echinococcus multilocularis expressed protein 0.0806 0.1704 0.1701
Trypanosoma brucei cytochrome P450, putative 0.0067 0.0085 0.019
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0789 0.1667 0.1664
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0086 0.0127 0.0346
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0051 0.0106
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0034 0.0013 0.0035
Loa Loa (eye worm) hypothetical protein 0.0054 0.0056 0.0055
Mycobacterium leprae Probable lipase LipE 0.0074 0.01 0.0639
Plasmodium falciparum plasmepsin IX 0.0172 0.0316 0.0842
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0034 0.0013 0.0022
Brugia malayi hypothetical protein 0.0051 0.0051 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0029 0.0079
Leishmania major cathepsin L-like protease 0.1969 0.4251 1
Mycobacterium leprae probable zinc metalloprotease 0.0098 0.0153 0.0994
Schistosoma mansoni microtubule-associated protein tau 0.1507 0.324 0.3238
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0034 0.0013 0.0009
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0029 0.0025
Entamoeba histolytica cysteine protease, putative 0.0926 0.1966 0.5437
Loa Loa (eye worm) hypothetical protein 0.0035 0.0015 0.0014
Onchocerca volvulus 0.0055 0.0059 0.0097
Echinococcus granulosus tm gpcr rhodopsin 0.1035 0.2205 0.2202
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.024 0.0463 0.046
Schistosoma mansoni biogenic amine receptor 0.0035 0.0015 0.0011

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1425 nM Inhibition of human muscarinic M1 receptor expressed in CHO cells after 5 hrs by luciferase reporter assay ChEMBL. 24900216
IC50 (binding) > 10000 nM Inhibition of human 5HT7 receptor expressed in CHO cells after 5 hrs by luciferase reporter assay ChEMBL. 24900216
IC50 (binding) > 10000 nM Inhibition of human 5HT4 receptor expressed in CHO cells after 5 hrs by luciferase reporter assay ChEMBL. 24900216
Inhibition (ADMET) = -3.67 % Inhibition of human CYP3A4 at 3 uM ChEMBL. 24900216
Inhibition (ADMET) = -0.39 % Inhibition of human CYP2A6 at 3 uM ChEMBL. 24900216
Inhibition (ADMET) = 3.64 % Inhibition of human CYP1A2 at 3 uM ChEMBL. 24900216
Inhibition (ADMET) = 10.81 % Inhibition of human CYP2A6 at 10 uM ChEMBL. 24900216
Inhibition (ADMET) = 17.9 % Inhibition of human CYP1A2 at 10 uM ChEMBL. 24900216
Inhibition (ADMET) = 22.76 % Inhibition of human CYP2C19 at 3 uM ChEMBL. 24900216
Inhibition (ADMET) = 32.89 % Inhibition of human CYP3A4 at 10 uM ChEMBL. 24900216
Inhibition (ADMET) = 43.59 % Inhibition of human CYP2C19 at 10 uM ChEMBL. 24900216
Inhibition (ADMET) = 48.33 % Inhibition of human CYP2D6 at 3 uM ChEMBL. 24900216
Inhibition (ADMET) = 76.23 % Inhibition of human CYP2D6 at 10 uM ChEMBL. 24900216
Ki (binding) = 2.56 nM Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells ChEMBL. 24900216

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.