Detailed information for compound 1602665

Basic information

Technical information
  • TDR Targets ID: 1602665
  • Name: 2-[2-[[2-[5-acetamido-3-hydroxy-2-(hydroxymet hyl)-6-(phenylmethoxy)oxan-4-yl]oxyacetyl]ami no]propanoylamino]-N'-[6-oxo-6-[(12-oxo-10H-i soindolo[1,2-b]quinazolin-8-yl)amino]hexyl]pe ntanediamide
  • MW: 912.983 | Formula: C46H56N8O12
  • H donors: 8 H acceptors: 9 LogP: -0.28 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 3
  • SMILES: OCC1OC(OCc2ccccc2)C(C(C1O)OCC(=O)NC(C(=O)NC(C(=O)N)CCC(=O)NCCCCCC(=O)Nc1ccc2c(c1)CN1C(=N2)c2c(C1=O)cccc2)C)NC(=O)C
  • InChi: 1S/C46H56N8O12/c1-26(49-38(59)25-64-41-39(50-27(2)56)46(66-35(23-55)40(41)60)65-24-28-11-5-3-6-12-28)44(62)53-34(42(47)61)18-19-36(57)48-20-10-4-7-15-37(58)51-30-16-17-33-29(21-30)22-54-43(52-33)31-13-8-9-14-32(31)45(54)63/h3,5-6,8-9,11-14,16-17,21,26,34-35,39-41,46,55,60H,4,7,10,15,18-20,22-25H2,1-2H3,(H2,47,61)(H,48,57)(H,49,59)(H,50,56)(H,51,58)(H,53,62)
  • InChiKey: GWQWQCJJTXJODG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[2-[[2-[5-acetamido-3-hydroxy-2-(hydroxymethyl)-6-(phenylmethoxy)tetrahydropyran-4-yl]oxyacetyl]amino]propanoylamino]-N'-[6-oxo-6-[(12-oxo-10H-isoindolo[1,2-b]quinazolin-8-yl)amino]hexyl]pentanediamide
  • 2-[[2-[[2-[[5-acetamido-3-hydroxy-2-(hydroxymethyl)-6-(phenylmethoxy)-4-tetrahydropyranyl]oxy]-1-oxoethyl]amino]-1-oxopropyl]amino]-N'-[6-oxo-6-[(12-oxo-10H-isoindolo[1,2-b]quinazolin-8-yl)amino]hexyl]pentanediamide
  • 2-[2-[[2-[3-acetamido-2-(benzyloxy)-5-hydroxy-6-methylol-tetrahydropyran-4-yl]oxyacetyl]amino]propanoylamino]-N'-[6-keto-6-[(12-keto-10H-isoindolo[1,2-b]quinazolin-8-yl)amino]hexyl]glutaramide
  • 2-[2-[2-[5-acetamido-3-hydroxy-2-(hydroxymethyl)-6-(phenylmethoxy)oxan-4-yl]oxyethanoylamino]propanoylamino]-N'-[6-oxo-6-[(12-oxo-10H-isoindolo[1,2-b]quinazolin-8-yl)amino]hexyl]pentanediamide
  • NCI60_041031

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0021 0.003
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0015 0.0016
Toxoplasma gondii kringle domain-containing protein 0.0066 0.0091 0.0287
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1253 0.2415 0.3433
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0064 0.0235
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0054
Giardia lamblia Cathepsin B precursor 0.0336 0.0619 0.2372
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0003 0.0003
Onchocerca volvulus 0.0031 0.0022 0.0073
Schistosoma mansoni biogenic amine (5HT) receptor 0.0072 0.0102 0.0123
Echinococcus multilocularis glycoprotein Antigen 5 0.0081 0.012 0.0119
Plasmodium vivax glutathione reductase, putative 0.0102 0.0161 0.0553
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.0161 0.0161
Echinococcus multilocularis Calcium binding protein 0.0028 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Loa Loa (eye worm) hypothetical protein 0.0155 0.0265 0.0376
Leishmania major hypothetical protein, conserved 0.0154 0.0263 0.0763
Brugia malayi Melatonin receptor type 1A 0.0072 0.0102 0.0145
Schistosoma mansoni intermediate filament proteins 0.0057 0.0073 0.0088
Schistosoma mansoni egf-like domain protein 0.0026 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0066 0.0091 0.0109
Schistosoma mansoni chromobox protein 0.0068 0.0094 0.0113
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0227 0.0406 0.1183
Loa Loa (eye worm) trypsin family protein 0.0081 0.012 0.0169
Plasmodium vivax aspartyl protease, putative 0.0034 0.0029 0.005
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0029 0.0018 0.0025
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Trypanosoma cruzi calmodulin, putative 0.015 0.0255 0.0359
Loa Loa (eye worm) hypothetical protein 0.3609 0.703 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Onchocerca volvulus Dual oxidase homolog 0.011 0.0177 0.0658
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0241 0.0295
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0072 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Trichomonas vaginalis centrin, putative 0.0028 0.0015 0.0048
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Brugia malayi calpain 5 0.0572 0.1082 0.1539
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.1059 0.2035 0.2035
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0336 0.0619 0.088
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0018 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0027 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0092 0.011
Echinococcus granulosus pyruvate kinase 0.0033 0.0026 0.0025
Plasmodium vivax calpain, putative 0.0965 0.1852 0.6967
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0154 0.0263 0.0322
Mycobacterium tuberculosis Conserved protein 0.004 0.0039 0.0774
Trypanosoma cruzi calmodulin, putative 0.015 0.0255 0.0359
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0022 0.0031
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Brugia malayi putative neuropeptide receptor NPR1 0.0072 0.0102 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Echinococcus multilocularis calpain A 0.237 0.4604 0.4603
Leishmania major pyruvate kinase 0.0033 0.0026 0.0067
Leishmania major calpain protease-like protein 0.0393 0.0731 0.2137
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0039 0.0774
Trypanosoma brucei Calpain-like protein 2 0.0758 0.1447 0.4237
Trypanosoma brucei metacaspase MCA2 0.0044 0.0046 0.0128
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0003 0.0002
Plasmodium vivax proteasome subunit beta type-5, putative 0.0075 0.0108 0.0351
Schistosoma mansoni ef hand domain family member A2 0.015 0.0255 0.0312
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.003 0.0057
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0743 0.1416 0.4147
Schistosoma mansoni hypothetical protein 0.0031 0.0022 0.0024
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0599 0.1134 0.161
Onchocerca volvulus 0.0072 0.0102 0.0374
Leishmania major metacaspase, putative 0.0044 0.0046 0.0128
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1137 0.333
Plasmodium vivax vivapain-1 0.0757 0.1443 0.5416
Onchocerca volvulus 0.0034 0.0029 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Onchocerca volvulus 0.0072 0.0102 0.0374
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0757 0.1443 0.1781
Trichomonas vaginalis conserved hypothetical protein 0.0336 0.0619 0.2328
Plasmodium falciparum plasmepsin III 0.0034 0.0029 0.0102
Schistosoma mansoni cathepsin s 0.0421 0.0785 0.0967
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0058 0.0082
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.003 0.003
Entamoeba histolytica cysteine proteinase, putative 0.1373 0.2651 1
Schistosoma mansoni reticulocalbin 0.015 0.0255 0.0312
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1225 0.236 0.2915
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0066 0.0091 0.0287
Onchocerca volvulus 0.0081 0.012 0.0442
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0003 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0046 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1137 0.333
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0072 0.0102 0.0144
Brugia malayi sulfakinin receptor protein 0.0072 0.0102 0.0145
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0012 0.0017
Echinococcus granulosus cathepsin l1 0.0953 0.1827 0.1827
Onchocerca volvulus Cathepsin L homolog 0.1373 0.2651 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0075 0.0108 0.015
Trypanosoma cruzi calmodulin, putative 0.015 0.0255 0.0359
Echinococcus multilocularis Smad4 0.0025 0.001 0.001
Onchocerca volvulus 0.0081 0.012 0.0442
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.003 0.0109
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0336 0.0619 0.0763
Brugia malayi MH1 domain containing protein 0.0025 0.001 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0336 0.0619 0.2328
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1348 0.2602 0.3699
Onchocerca volvulus 0.0072 0.0102 0.0374
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0336 0.0619 0.2291
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.0102 0.0101
Brugia malayi Animal haem peroxidase family protein 0.011 0.0177 0.0251
Echinococcus multilocularis sodium channel protein 0.0039 0.0037 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.003 0.0039
Loa Loa (eye worm) calpain 0.0965 0.1852 0.2633
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0421 0.0785 0.1116
Giardia lamblia Cathepsin L precursor 0.0336 0.0619 0.2372
Schistosoma mansoni hypothetical protein 0.0057 0.0073 0.0087
Leishmania major hypothetical protein, conserved 0.063 0.1195 0.3498
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0026 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.0102 0.0101
Trypanosoma brucei unspecified product 0.0227 0.0406 0.1183
Onchocerca volvulus 0.0031 0.0022 0.0073
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0421 0.0785 0.1116
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0336 0.0619 0.088
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0021
Giardia lamblia Cathepsin B precursor 0.0336 0.0619 0.2372
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0965 0.1852 0.2631
Plasmodium vivax plasmepsin V, putative 0.0034 0.0029 0.005
Echinococcus multilocularis geminin 0.0855 0.1636 0.1636
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.062 0.1176 0.1669
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0039 0.0136
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.012 0.0145
Echinococcus multilocularis caspase 8 0.0044 0.0046 0.0046
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0336 0.0619 0.0881
Brugia malayi Cytochrome P450 family protein 0.0034 0.0028 0.004
Plasmodium falciparum plasmepsin I 0.0146 0.0246 0.0925
Plasmodium falciparum serine repeat antigen 9 0.0336 0.0619 0.2331
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Schistosoma mansoni hypothetical protein 0.0072 0.0102 0.0123
Leishmania major hypothetical protein, conserved 0.0227 0.0406 0.1183
Onchocerca volvulus 0.0031 0.0022 0.0073
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0089 0.0134 0.0163
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0072 0.0102 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0054
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.003 0.2372
Echinococcus granulosus chromobox protein 1 0.0068 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0054
Brugia malayi Cathepsin L-like cysteine proteinase 0.0953 0.1827 0.2599
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2366 0.4596 0.568
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0022 0.0031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3609 0.703 0.869
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0953 0.1827 0.689
Brugia malayi Matrixin family protein 0.0024 0.0009 0.0012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0039 0.0055
Echinococcus granulosus calpain A 0.0965 0.1852 0.1851
Echinococcus granulosus neurocalcin 0.015 0.0255 0.0254
Toxoplasma gondii microneme protein, putative 0.0031 0.0022 0.0025
Onchocerca volvulus 0.011 0.0177 0.0658
Echinococcus granulosus neuropeptide Y receptor 0.0072 0.0102 0.0101
Onchocerca volvulus 0.0081 0.012 0.0442
Onchocerca volvulus Matrilysin homolog 0.0054 0.0066 0.0241
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0026 0.0087
Trypanosoma cruzi caltractin, putative 0.015 0.0255 0.0359
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0075 0.0108 0.015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0336 0.0619 0.0763
Echinococcus granulosus dnaJ subfamily B 0.0403 0.0751 0.0751
Echinococcus granulosus calmodulin 0.015 0.0255 0.0254
Echinococcus granulosus bloom syndrome protein 0.0024 0.0007 0.0007
Toxoplasma gondii cathepsin CPC2 0.0336 0.0619 0.2291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.015 0.0255 0.0909
Onchocerca volvulus 0.015 0.0255 0.0953
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0003 0.0003
Schistosoma mansoni alpha-1 adrenergic receptor 0.0072 0.0102 0.0123
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.003 0.0039
Schistosoma mansoni histamine h1 receptor 0.0072 0.0102 0.0123
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0223 0.0397 0.0488
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Brugia malayi Cathepsin L-like precursor 0.1373 0.2651 0.3771
Onchocerca volvulus 0.0336 0.0619 0.2328
Echinococcus multilocularis cathepsin L cysteine protease 0.1373 0.2651 0.2651
Schistosoma mansoni hypothetical protein 0.0023 0.0007 0.0006
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0034 0.0029 0.005
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0057 0.0073 0.0072
Toxoplasma gondii hypothetical protein 0.0031 0.0022 0.0025
Leishmania major hypothetical protein, unknown function 0.0393 0.0731 0.2137
Loa Loa (eye worm) hypothetical protein 0.1059 0.2035 0.2894
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trypanosoma brucei small myristoylated protein 1-1 0.0392 0.0728 0.2129
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0046 0.0118
Brugia malayi Matrixin family protein 0.0059 0.0076 0.0108
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0016
Leishmania major small myristoylated protein-3, putative 0.0332 0.0611 0.1785
Giardia lamblia Cathepsin B precursor 0.0336 0.0619 0.2372
Echinococcus granulosus lamin dm0 0.0057 0.0073 0.0073
Mycobacterium ulcerans proteasome PrcB 0.0075 0.0108 0.901
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0003 0.0004
Brugia malayi CXXC zinc finger family protein 0.0057 0.0073 0.0104
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0022 0.0021
Echinococcus granulosus cysteine protease 0.0757 0.1443 0.1443
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0039 0.0774
Toxoplasma gondii cathepsin CPL 0.1373 0.2651 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0003 0.0003
Giardia lamblia Cathepsin B precursor 0.0336 0.0619 0.2372
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0042
Schistosoma mansoni cathepsin C 0.0336 0.0619 0.0763
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.015 0.0255 0.0312
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0336 0.0619 0.2328
Loa Loa (eye worm) hypothetical protein 0.0041 0.0041 0.0058
Mycobacterium tuberculosis Probable reductase 0.0233 0.0418 0.8906
Echinococcus granulosus peroxidasin 0.011 0.0177 0.0176
Brugia malayi cathepsin F-like cysteine proteinase 0.0336 0.0619 0.0881
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0036 0.0125
Brugia malayi Cytochrome P450 family protein 0.0033 0.0027 0.0038
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0161 0.0229
Schistosoma mansoni amine GPCR 0.0072 0.0102 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Giardia lamblia Proteasome subunit beta type 1 0.0057 0.0073 0.027
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0146 0.0246 0.0302
Schistosoma mansoni memapsin-2 (A01 family) 0.0034 0.0029 0.0032
Trichomonas vaginalis calcium binding protein, putative 0.0178 0.0309 0.1158
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0088 0.0134 0.0133
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Echinococcus granulosus neuronal calcium sensor 0.015 0.0255 0.0254
Schistosoma mansoni survival motor neuron protein 0.0051 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0046 0.0165
Trypanosoma cruzi cysteine peptidase, putative 0.1761 0.3411 0.4849
Onchocerca volvulus 0.1251 0.2411 0.9094
Schistosoma mansoni dopamine-beta-monooxygenase 0.0129 0.0213 0.026
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0154 0.0263 0.037
Echinococcus granulosus caspase 2 0.0085 0.0127 0.0126
Schistosoma mansoni cathepsin D (A01 family) 0.043 0.0803 0.0989
Echinococcus multilocularis g protein coupled receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis calpain 7 (C02 family) 0.0965 0.1852 0.1851
Brugia malayi Trypsin family protein 0.0081 0.012 0.017
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0043 0.0106
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0085 0.0084
Onchocerca volvulus 0.0072 0.0102 0.0374
Echinococcus multilocularis cysteine protease 0.1373 0.2651 0.2651
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0003 0.0004
Trypanosoma brucei calpain-like protein, putative 0.0965 0.1852 0.5426
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1373 0.2651 0.3771
Schistosoma mansoni mitochondrial solute carrier 0.015 0.0255 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0336 0.0619 0.2328
Echinococcus multilocularis tissue type plasminogen activator 0.0066 0.0091 0.0091
Schistosoma mansoni peroxidasin 0.011 0.0177 0.0215
Schistosoma mansoni cathepsin S (C01 family) 0.0336 0.0619 0.0763
Brugia malayi cathepsin Z-like cysteine proteinase 0.0336 0.0619 0.0881
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Onchocerca volvulus 0.0072 0.0102 0.0374
Echinococcus multilocularis fmrfamide receptor 0.0072 0.0102 0.0101
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0288 0.0525 0.1532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0021
Plasmodium vivax unspecified product 0.0757 0.1443 0.5416
Echinococcus multilocularis transmembrane protease serine 3 0.0081 0.012 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0003 0.0004
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0028 0.0015 0.0049
Echinococcus multilocularis calcyphosin protein 0.0028 0.0015 0.0015
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.015 0.0255 0.0359
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.006 0.0086
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0027 0.0034
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0057 0.0073 0.0265
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0021
Leishmania major cathepsin L-like protease 0.1761 0.3411 1
Trypanosoma cruzi cysteine peptidase, putative 0.0757 0.1443 0.2049
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0006 0.0008
Brugia malayi Calmodulin-like protein 0.015 0.0255 0.0363
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Loa Loa (eye worm) hypothetical protein 0.0249 0.0449 0.0637
Giardia lamblia Cathepsin L precursor 0.0336 0.0619 0.2372
Trichomonas vaginalis calmodulin, putative 0.0178 0.0309 0.1158
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.015 0.0255 0.0952
Echinococcus multilocularis muscleblind protein 0.015 0.0255 0.0254
Trypanosoma brucei conserved protein 0.0237 0.0425 0.1239
Onchocerca volvulus 0.1373 0.2651 1
Schistosoma mansoni hypothetical protein 0.0855 0.1636 0.202
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0078 0.0114 0.0137
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0046 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0003 0.0004
Schistosoma mansoni inositol transporter 0.415 0.8089 1
Loa Loa (eye worm) RNA binding protein 0.0067 0.0092 0.013
Onchocerca volvulus 0.0072 0.0102 0.0374
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0022 0.0031
Trypanosoma brucei kinesin, putative 0.0572 0.1082 0.3166
Echinococcus multilocularis caspase 3 0.0071 0.0101 0.01
Brugia malayi Thioredoxin reductase 0.0102 0.0161 0.0229
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0092 0.013
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0007 0.0007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0008 0.0021
Onchocerca volvulus 0.015 0.0255 0.0953
Echinococcus granulosus tissue type plasminogen activator 0.0066 0.0091 0.0091
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0043 0.0106
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3609 0.703 0.869
Onchocerca volvulus Cathepsin L homolog 0.0336 0.0619 0.2328
Loa Loa (eye worm) hypothetical protein 0.0098 0.0153 0.0218
Schistosoma mansoni calpain C (C02 family) 0.0965 0.1852 0.2287
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1253 0.2415 0.3433
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0342 0.042
Echinococcus granulosus biogenic amine 5HT receptor 0.0072 0.0102 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0336 0.0619 0.2328
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0026 0.0493
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0336 0.0619 0.2328
Onchocerca volvulus 0.011 0.0177 0.0658
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Mycobacterium tuberculosis Probable dehydrogenase 0.0233 0.0418 0.8906
Schistosoma mansoni myosin xvIII 0.0072 0.0102 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0421 0.0785 0.1116
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.003 0.0057
Leishmania major small myristoylated protein-1 0.0392 0.0728 0.2129
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni calmodulin related calcium binding protein 0.015 0.0255 0.0312
Plasmodium falciparum cysteine proteinase falcipain 3 0.1373 0.2651 1
Schistosoma mansoni neuronal calcium sensor 0.015 0.0255 0.0312
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.062 0.1176 0.3442
Mycobacterium ulcerans hydrolase 0.003 0.0019 0.139
Echinococcus multilocularis proteasome (prosome, macropain) 0.0075 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0046 0.0066
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.062 0.1176 0.3442
Echinococcus multilocularis calpain family protein 1, d 0.1644 0.3181 0.3181
Plasmodium falciparum glutathione reductase 0.0035 0.003 0.0109
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.001 0.0014
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.001 0.001
Trichomonas vaginalis centrin, putative 0.015 0.0255 0.0952
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1137 0.1615
Schistosoma mansoni neuronal calcium sensor 0.015 0.0255 0.0312
Plasmodium falciparum plasmepsin IX 0.0034 0.0029 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0014 0.0042
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.088 0.1684 0.4934
Onchocerca volvulus Matrix metalloproteinase homolog 0.0054 0.0066 0.0241
Schistosoma mansoni hypothetical protein 0.0072 0.0102 0.0123
Onchocerca volvulus 0.0081 0.012 0.0442
Schistosoma mansoni hypothetical protein 0.0041 0.0041 0.0048
Entamoeba histolytica calmodulin, putative 0.0028 0.0015 0.0048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0018
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0064 0.0183
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2366 0.4596 0.4596
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0227 0.0406 0.0573
Schistosoma mansoni pyruvate kinase 0.0033 0.0026 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0085 0.0127 0.018
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.0342 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0757 0.1443 0.5438
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0336 0.0619 0.2328
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0003 0.0002
Trichomonas vaginalis set domain proteins, putative 0.0521 0.0981 0.3695
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Brugia malayi follicle stimulating hormone receptor 0.0072 0.0102 0.0145
Echinococcus multilocularis programmed cell death protein 0.0178 0.0309 0.0309
Brugia malayi calpain D 0.0393 0.0731 0.104
Echinococcus multilocularis Tolloid protein 1 0.009 0.0137 0.0136
Giardia lamblia Hypothetical protein 0.0154 0.0263 0.1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.062 0.1176 0.1669
Plasmodium falciparum plasmepsin VIII, putative 0.0034 0.0029 0.0102
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Leishmania major centrin, putative 0.015 0.0255 0.074
Echinococcus multilocularis caspase 2 0.0085 0.0127 0.0126
Schistosoma mansoni biogenic amine receptor 0.0072 0.0102 0.0123
Echinococcus multilocularis cysteine protease 0.1373 0.2651 0.2651
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0393 0.0731 0.275
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Brugia malayi Pre-SET motif family protein 0.0458 0.0858 0.122
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0161 0.0226
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0081 0.012 0.0145
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0073 0.0104
Plasmodium falciparum serine repeat antigen 8 0.0336 0.0619 0.2331
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0945 0.1811 0.5307
Leishmania major hypothetical protein, conserved 0.0227 0.0406 0.1183
Toxoplasma gondii centrin 0.015 0.0255 0.0909
Trypanosoma cruzi cysteine peptidase, putative 0.0421 0.0785 0.1113
Plasmodium falciparum centrin-1 0.015 0.0255 0.0956
Onchocerca volvulus 0.004 0.0039 0.0137
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0242 0.0435 0.0619
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0758 0.1447 0.4237
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0115 0.0186 0.0186
Echinococcus granulosus calcyphosin protein 0.0028 0.0015 0.0015
Onchocerca volvulus Peroxidase homolog 0.011 0.0177 0.0658
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Schistosoma mansoni centrin-related 0.015 0.0255 0.0312
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0036 0.0128
Brugia malayi RNA binding protein 0.0067 0.0092 0.0131
Leishmania major calmodulin-like protein 0.015 0.0255 0.074
Brugia malayi MH2 domain containing protein 0.0369 0.0683 0.0971
Brugia malayi hypothetical protein 0.0134 0.0224 0.0318
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0057 0.0073 0.01
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0003 0.0004
Toxoplasma gondii centrin, putative 0.015 0.0255 0.0909
Brugia malayi Animal haem peroxidase family protein 0.011 0.0177 0.0251
Echinococcus granulosus dna polymerase kappa 0.0021 0.0003 0.0002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0081
Echinococcus multilocularis chromobox protein 1 0.0068 0.0094 0.0094
Onchocerca volvulus Peroxidasin homolog 0.011 0.0177 0.0658
Echinococcus multilocularis pyruvate kinase 0.0033 0.0026 0.0025
Trypanosoma cruzi I/6 autoantigen, putative 0.015 0.0255 0.0359
Loa Loa (eye worm) hypothetical protein 0.0953 0.1827 0.2599
Brugia malayi hypothetical protein 0.0034 0.0029 0.0041
Leishmania major hypothetical protein, conserved 0.0227 0.0406 0.1183
Onchocerca volvulus 0.0072 0.0102 0.0374
Entamoeba histolytica calmodulin, putative 0.015 0.0255 0.0952
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0057 0.0073 0.0269
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0007 0.0017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0992 0.1904 0.2706
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Echinococcus multilocularis calumenin 0.0154 0.0263 0.0262
Echinococcus granulosus calbindin 32 0.0154 0.0263 0.0262
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0029 0.0051
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0064 0.0183
Brugia malayi Protein kinase domain containing protein 0.0066 0.0091 0.013
Brugia malayi EF hand family protein 0.0154 0.0263 0.0374
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0026 0.0067
Brugia malayi steroid hormone receptor 0.0021 0.0003 0.0004
Leishmania major cytochrome p450-like protein 0.0033 0.0027 0.007
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0146 0.0246 0.0246
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0146 0.0246 0.0877
Mycobacterium tuberculosis Conserved protein 0.004 0.0039 0.0774
Schistosoma mansoni calmodulin 0.015 0.0255 0.0312
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0003 0.0002
Brugia malayi Trypsin-like protease protein 5 0.0081 0.012 0.017
Schistosoma mansoni hypothetical protein 0.0051 0.006 0.0072
Loa Loa (eye worm) myosin regulatory light chain 1 0.0028 0.0015 0.0021
Loa Loa (eye worm) ctsf protein 0.1373 0.2651 0.3771
Trypanosoma brucei calmodulin, putative 0.0154 0.0263 0.0763
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Toxoplasma gondii thioredoxin reductase 0.0102 0.0161 0.0553
Onchocerca volvulus 0.0057 0.0073 0.0267
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Leishmania major cathepsin L-like protease 0.1761 0.3411 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Trypanosoma brucei Metacaspase-4 0.0044 0.0046 0.0128
Trypanosoma cruzi kinesin, putative 0.0572 0.1082 0.1535
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Giardia lamblia Hypothetical protein 0.0336 0.0619 0.2372
Trichomonas vaginalis caltractin, putative 0.0028 0.0015 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1173 0.2258 0.6618
Onchocerca volvulus 0.0031 0.0022 0.0073
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus granulosus hypothetical protein 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Trypanosoma brucei cysteine peptidase, putative 0.062 0.1176 0.3442
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1373 0.2651 0.3771
Brugia malayi Hemopexin family protein 0.0034 0.0028 0.004
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0394 0.0732 0.214
Leishmania major cysteine peptidase A (CPA) 0.1373 0.2651 0.7772
Schistosoma mansoni biogenic amine receptor 0.0072 0.0102 0.0123
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0757 0.1443 0.1781
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0072 0.0102 0.0123
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Echinococcus multilocularis allatostatin A receptor 0.0072 0.0102 0.0101
Giardia lamblia Cysteine protease 0.0336 0.0619 0.2372
Loa Loa (eye worm) fibroinase 0.1373 0.2651 0.3771
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0003 0.0004
Plasmodium falciparum plasmepsin V 0.0034 0.0029 0.0102
Echinococcus multilocularis cpg binding protein 0.0061 0.008 0.0079
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.003 0.0105
Leishmania major calmodulin, putative 0.015 0.0255 0.074
Echinococcus multilocularis cathepsin L cysteine protease 0.1373 0.2651 0.2651
Schistosoma mansoni Mername-AA248 (C02 family) 0.0965 0.1852 0.2287
Loa Loa (eye worm) hypothetical protein 0.0044 0.0046 0.0065
Schistosoma mansoni reticulocalbin 0.0154 0.0263 0.0322
Brugia malayi Cathepsin L-like precursor 0.1373 0.2651 0.3771
Brugia malayi neuropeptide F receptor 0.0072 0.0102 0.0145
Loa Loa (eye worm) hypothetical protein 0.1373 0.2651 0.3771
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0003 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0021
Echinococcus multilocularis prefoldin subunit 6 0.0066 0.0091 0.009
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0023 0.0033
Schistosoma mansoni calpain-2 (C02 family) 0.0393 0.0731 0.0901
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0945 0.1811 0.5307
Onchocerca volvulus 0.0072 0.0102 0.0374
Trypanosoma cruzi metacaspase, putative 0.0044 0.0046 0.0062
Onchocerca volvulus 0.0072 0.0102 0.0374
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Trypanosoma cruzi centrin, putative 0.0178 0.0309 0.0436
Brugia malayi ORL1-like opioid receptor 0.0072 0.0102 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0026 0.0087
Plasmodium falciparum thioredoxin reductase 0.0102 0.0161 0.0603
Toxoplasma gondii preprocathepsin c precursor, putative 0.0336 0.0619 0.2291
Trichomonas vaginalis calmodulin, putative 0.0028 0.0015 0.0048
Plasmodium vivax hypothetical protein, conserved 0.004 0.0039 0.0089
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Onchocerca volvulus 0.0072 0.0102 0.0374
Schistosoma mansoni amine GPCR 0.0072 0.0102 0.0123
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0022 0.0025
Echinococcus multilocularis G-protein coupled receptor, putative 0.0072 0.0102 0.0101
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0036 0.013
Leishmania major proteasome beta 5 subunit, putative 0.0075 0.0108 0.0309
Trypanosoma brucei Calpain-like protein 1.1 0.0992 0.1904 0.558
Plasmodium vivax aspartyl proteinase, putative 0.0034 0.0029 0.005
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1137 0.333
Giardia lamblia Programmed cell death protein-like protein 0.0028 0.0015 0.0049
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.012 0.012
Echinococcus multilocularis calcium uptake protein 1 0.0154 0.0263 0.0262
Mycobacterium ulcerans hypothetical protein 0.004 0.0039 0.3087
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0336 0.0619 0.2328
Leishmania major hypothetical protein, conserved 0.015 0.0255 0.074
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0336 0.0619 0.0763
Trichomonas vaginalis calpain, putative 0.0393 0.0731 0.275
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Echinococcus granulosus geminin 0.0855 0.1636 0.1636
Loa Loa (eye worm) hypothetical protein 0.0146 0.0246 0.035
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0336 0.0619 0.2331
Loa Loa (eye worm) hypothetical protein 0.0336 0.0619 0.088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0336 0.0619 0.2328
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0039 0.0038
Plasmodium falciparum serine repeat antigen 1 0.0336 0.0619 0.2331
Giardia lamblia Cysteine protease 0.0336 0.0619 0.2372
Brugia malayi MH1 domain containing protein 0.0025 0.001 0.0015
Echinococcus granulosus cathepsin L cysteine protease 0.0757 0.1443 0.1443
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0177 0.0251
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0757 0.1443 0.1781
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0039
Trypanosoma brucei prefoldin subunit, putative 0.0066 0.0091 0.0259
Onchocerca volvulus Matrilysin homolog 0.0024 0.0009 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0072 0.0102 0.0123
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0072 0.0102 0.0101
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0058 0.0078
Echinococcus multilocularis neuropeptide Y receptor 0.0072 0.0102 0.0101
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0288 0.0525 0.1532
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0046 0.0054
Brugia malayi Cathepsin L-like precursor 0.1373 0.2651 0.3771
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.062 0.1176 0.1669
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0092 0.0111
Entamoeba histolytica grainin 2 0.0178 0.0309 0.1158
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0336 0.0619 0.2328
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Echinococcus granulosus Mastin 0.0081 0.012 0.0119
Trichomonas vaginalis calcium binding proteins, putative 0.015 0.0255 0.0952
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0026 0.0039
Brugia malayi Kringle domain containing protein 0.0066 0.0091 0.013
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0072 0.0102 0.0101
Giardia lamblia Cathepsin L precursor 0.0336 0.0619 0.2372
Echinococcus granulosus sodium channel protein 0.0039 0.0037 0.0036
Trypanosoma cruzi major cysteine proteinase, putative 0.0336 0.0619 0.0877
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.062 0.1176 0.1669
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0026 0.0036
Trypanosoma cruzi cruzipain precursor, putative 0.0421 0.0785 0.1113
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0022 0.0025
Schistosoma mansoni opsin-like receptor 0.0072 0.0102 0.0123
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0018 0.0025
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0022 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Brugia malayi putative neuropeptide receptor 0.0072 0.0102 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0757 0.1443 0.5438
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0092 0.0111
Loa Loa (eye worm) hypothetical protein 0.0086 0.013 0.0184
Echinococcus granulosus cathepsin b 0.3609 0.703 0.703
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0336 0.0619 0.2328
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0022 0.0031
Trypanosoma brucei calpain, putative 0.0393 0.0731 0.2137
Trypanosoma cruzi small myristoylated protein 1-2 0.0392 0.0728 0.1032
Plasmodium falciparum centrin-4 0.0028 0.0015 0.0052
Echinococcus granulosus neuropeptides capa receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) programmed cell death protein 6 0.0154 0.0263 0.0373
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0072 0.0102 0.0101
Brugia malayi ecdysteroid receptor 0.0021 0.0003 0.0004
Trypanosoma brucei hypothetical protein 0.0681 0.1295 0.3791
Echinococcus multilocularis g protein coupled receptor 0.0072 0.0102 0.0101
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0065 0.0089 0.0126
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.012 0.0145
Trichomonas vaginalis calpain, putative 0.0393 0.0731 0.275
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1253 0.2415 0.708
Brugia malayi Myosin regulatory light chain 1 0.0028 0.0015 0.0022
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.001 0.001
Entamoeba histolytica cysteine proteinase, putative 0.0757 0.1443 0.5438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0336 0.0619 0.2328
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus granulosus Calcium binding protein 0.0028 0.0015 0.0015
Echinococcus multilocularis pyruvate kinase 0.0033 0.0026 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.016 0.0274 0.0274
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3609 0.703 0.869
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0336 0.0619 0.088
Echinococcus multilocularis neuropeptide s receptor 0.0072 0.0102 0.0101
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0041 0.0146
Brugia malayi cathepsin L-like precursor 0.0953 0.1827 0.2599
Giardia lamblia Cysteine protease 0.0336 0.0619 0.2372
Onchocerca volvulus 0.004 0.0039 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0336 0.0619 0.2328
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0036 0.0125
Plasmodium vivax vivapain-2 0.1373 0.2651 1
Echinococcus granulosus programmed cell death protein 6 0.0032 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis hypothetical protein 0.0965 0.1852 0.1851
Schistosoma mansoni caspase-7 (C14 family) 0.0115 0.0186 0.0227
Schistosoma mansoni hypothetical protein 0.0031 0.0022 0.0024
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0043 0.0043
Echinococcus granulosus g protein coupled receptor 0.0072 0.0102 0.0101
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0058 0.0161
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0204 0.0249
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0039 0.0136
Loa Loa (eye worm) calpain family protein 1 0.2216 0.4302 0.6119
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0041 0.0147
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0072 0.0102 0.0144
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0003 0.0002
Onchocerca volvulus 0.1373 0.2651 1
Onchocerca volvulus 0.004 0.0039 0.0137
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1173 0.2258 0.3209
Brugia malayi aspartic protease BmAsp-1, identical 0.0034 0.0029 0.0041
Brugia malayi Pepsin A precursor 0.0034 0.0029 0.0041
Plasmodium vivax unspecified product 0.0421 0.0785 0.2919
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0072 0.0102 0.0101
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.0611 0.0865
Schistosoma mansoni neuronal calcium sensor 0.015 0.0255 0.0312
Brugia malayi Peroxidasin 0.011 0.0177 0.0251
Echinococcus granulosus intermediate filament protein 0.0057 0.0073 0.0073
Entamoeba histolytica cysteine proteinase, putative 0.0757 0.1443 0.5438
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0057 0.0073 0.01
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Echinococcus multilocularis centrin 2 0.015 0.0255 0.0254
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0022 0.0031
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2366 0.4596 0.4596
Brugia malayi Dopamine receptor protein 1 0.0072 0.0102 0.0145
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0255 0.0952
Echinococcus multilocularis EF HAND 1, calcium binding site 0.015 0.0255 0.0254
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trypanosoma cruzi metacaspase, putative 0.0044 0.0046 0.0062
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0003 0.0004
Echinococcus granulosus caspase 3 0.0071 0.0101 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0039
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Brugia malayi Trypsin family protein 0.0081 0.012 0.017
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Loa Loa (eye worm) matrixin family protein 0.0054 0.0066 0.0094
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0336 0.0619 0.2372
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0139 0.0233 0.0232
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0064 0.0087
Echinococcus granulosus GPCR family 2 0.0031 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0336 0.0619 0.088
Brugia malayi AKH receptor 0.0072 0.0102 0.0145
Trypanosoma cruzi hypothetical protein, conserved 0.0368 0.0681 0.0966
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0342 0.0342
Onchocerca volvulus 0.0953 0.1827 0.689
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0057 0.0073 0.0206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0336 0.0619 0.2328
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0288 0.0525 0.0743
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0043 0.0154
Echinococcus multilocularis programmed cell death protein 0.0178 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0056 0.0071 0.0101
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0336 0.0619 0.2372
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0072 0.0102 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Plasmodium falciparum serine repeat antigen 7 0.0336 0.0619 0.2331
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0039 0.0051
Toxoplasma gondii prefoldin subunit 6, putative 0.0066 0.0091 0.0286
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0336 0.0619 0.2291
Echinococcus multilocularis Mastin 0.0081 0.012 0.0119
Echinococcus multilocularis enteropeptidase 0.0081 0.012 0.0119
Brugia malayi Dopamine receptor 0.0072 0.0102 0.0145
Echinococcus granulosus 7TM GPCR rhodopsin 0.0072 0.0102 0.0101
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0601 0.1137 0.1615
Entamoeba histolytica cysteine protease, putative 0.0336 0.0619 0.2328
Schistosoma mansoni peptidylglycine monooxygenase 0.0129 0.0213 0.026
Onchocerca volvulus Cathepsin L homolog 0.1373 0.2651 1
Echinococcus multilocularis cathepsin L 0.0757 0.1443 0.1443
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Brugia malayi fibroinase precursor 0.0336 0.0619 0.0881
Onchocerca volvulus 0.0072 0.0102 0.0374
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.003 0.0057
Echinococcus multilocularis muscleblind protein 1 0.015 0.0255 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0681 0.1295 0.3791
Leishmania major cathepsin L-like protease 0.1373 0.2651 0.7772
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0336 0.0619 0.2291
Brugia malayi Matrixin family protein 0.0024 0.0009 0.0012
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0034 0.0029 0.004
Onchocerca volvulus 0.0031 0.0022 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0015 0.0018
Brugia malayi MH2 domain containing protein 0.0025 0.001 0.0015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0003 0.0002
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0072 0.0102 0.0123
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0039 0.0774
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.1059 0.2035 0.2894
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0336 0.0619 0.2331
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0041 0.0041
Schistosoma mansoni neuropeptide receptor 0.0072 0.0102 0.0123
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Onchocerca volvulus 0.0066 0.0091 0.0335
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0022 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Brugia malayi GnHR receptor homolog 0.0072 0.0102 0.0145
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.015 0.0255 0.0359
Schistosoma mansoni centrin 0.015 0.0255 0.0312
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.012 0.0145
Brugia malayi G protein-coupled receptor F59B2.13 0.0072 0.0102 0.0145
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.003 0.2372
Giardia lamblia Cathepsin L-like protease 0.0336 0.0619 0.2372
Mycobacterium ulcerans lipase LipD 0.004 0.0039 0.3087
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0227 0.0406 0.1183
Echinococcus multilocularis laminin 0.0029 0.0018 0.0017
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.003 0.0081
Onchocerca volvulus 0.0072 0.0102 0.0374
Echinococcus multilocularis neuropeptide receptor A26 0.0072 0.0102 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0046 0.0165
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0255 0.0952
Loa Loa (eye worm) glutathione reductase 0.0102 0.0161 0.0229
Echinococcus multilocularis solute carrier family 5 0.415 0.8089 0.8089
Schistosoma mansoni hypothetical protein 0.0067 0.0093 0.0111
Plasmodium falciparum cysteine repeat modular protein 1 0.0066 0.0091 0.0338
Echinococcus multilocularis dro:myosuppressin receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0003 0.0002
Echinococcus multilocularis calpain 0.0965 0.1852 0.1851
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0072 0.0102 0.0101
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0026 0.0039
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis GPCR, family 2 0.0031 0.0022 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0778 0.1485 0.2109
Brugia malayi Papain family cysteine protease containing protein 0.1373 0.2651 0.3771
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0757 0.1443 0.4226
Echinococcus granulosus peptide allatostatin:somatostatin 0.0072 0.0102 0.0101
Loa Loa (eye worm) G-protein coupled receptor 0.0072 0.0102 0.0144
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0075 0.0108 0.2259
Mycobacterium tuberculosis Probable oxidoreductase 0.0259 0.0469 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0039 0.0136
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0075 0.0108 0.0309
Echinococcus multilocularis fibrillin 1 0.0029 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.1823 0.3532 0.5024
Echinococcus multilocularis neuropeptide receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0778 0.1485 0.4349
Brugia malayi EF hand family protein 0.015 0.0255 0.0363
Loa Loa (eye worm) hypothetical protein 0.0067 0.0092 0.013
Echinococcus granulosus serotonin receptor 0.0072 0.0102 0.0101
Leishmania major DNA polymerase eta, putative 0.0035 0.0029 0.0077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0039 0.0045
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Schistosoma mansoni lamin 0.0057 0.0073 0.0088
Brugia malayi hypothetical protein 0.0041 0.0041 0.0059
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.0342 0.0487
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.003 0.5
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0336 0.0619 0.2291
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0336 0.0619 0.2291
Trypanosoma cruzi major cysteine proteinase, putative 0.0724 0.1379 0.1958
Brugia malayi hypothetical protein 0.0249 0.0449 0.0638
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0336 0.0619 0.2328
Schistosoma mansoni cathepsin F (C01 family) 0.0953 0.1827 0.2257
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0003 0.0002
Echinococcus granulosus Smad4 0.0025 0.001 0.001
Entamoeba histolytica cysteine proteinase 1, putative 0.0757 0.1443 0.5438
Schistosoma mansoni smad 0.0025 0.001 0.001
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0393 0.0731 0.275
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0393 0.0731 0.2137
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.003 0.5
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0072 0.0102 0.0374
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0072 0.0102 0.0144
Brugia malayi G-protein coupled receptor 0.0072 0.0102 0.0145
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0743 0.1416 0.2011
Schistosoma mansoni pyruvate kinase 0.0033 0.0026 0.0029
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.0449 0.0448
Echinococcus granulosus solute carrier family 5 0.415 0.8089 0.8089
Brugia malayi Neuronal calcium sensor family protein 1 0.0028 0.0015 0.0022
Schistosoma mansoni lamin 0.0057 0.0073 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0255 0.0952
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0022 0.0031
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.003 0.0595
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.0102 0.0101
Brugia malayi Smad1 0.0025 0.001 0.0015
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0092 0.0092
Trypanosoma brucei metacaspase 0.0044 0.0046 0.0128
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Brugia malayi RE15519p 0.0072 0.0102 0.0145
Giardia lamblia Cathepsin L precursor 0.0336 0.0619 0.2372
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0021
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0092 0.013
Echinococcus multilocularis cathepsin b 0.3609 0.703 0.703
Leishmania major protein kinase, putative 0.015 0.0255 0.074
Schistosoma mansoni smad1 5 8 and 0.0025 0.001 0.001
Plasmodium vivax vivapain-3 0.0757 0.1443 0.5416
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0043 0.0154
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0073 0.0105
Echinococcus multilocularis neuropeptides capa receptor 0.0072 0.0102 0.0101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0026 0.0033
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.003 0.0081
Echinococcus multilocularis dna polymerase eta 0.0049 0.0058 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0003 0.0004
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Plasmodium vivax vivapain-2 0.1373 0.2651 1
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0227 0.0406 0.0573
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0161 0.0553
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0031 0.0022 0.0024
Onchocerca volvulus 0.0031 0.0022 0.0073
Brugia malayi Proteasome A-type and B-type family protein 0.0075 0.0108 0.0154
Onchocerca volvulus Neuropeptide F receptor homolog 0.0072 0.0102 0.0374
Entamoeba histolytica calcium-binding protein, putative 0.015 0.0255 0.0952
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1348 0.2602 0.9814
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0965 0.1852 0.2631
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0336 0.0619 0.2328
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0072 0.0102 0.0123
Toxoplasma gondii calmodulin CAM1 0.0154 0.0263 0.0938
Trichomonas vaginalis calcium binding protein, putative 0.0028 0.0015 0.0048
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0081 0.012 0.0119
Trypanosoma brucei small myristoylated protein 1-2 0.0392 0.0728 0.2129
Trichomonas vaginalis conserved hypothetical protein 0.0393 0.0731 0.275
Schistosoma mansoni myosin light chain 0.0028 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0072 0.0102 0.0144
Brugia malayi Probable myosin regulatory light chain 0.0032 0.0023 0.0033
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0039 0.0037 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0945 0.1811 0.5307
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0072 0.0102 0.0123
Schistosoma mansoni caspase-3 (C14 family) 0.0115 0.0186 0.0227
Leishmania major hypothetical protein, conserved 0.0227 0.0406 0.1183
Schistosoma mansoni microtubule-associated protein tau 0.0682 0.1298 0.1602
Entamoeba histolytica cysteine proteinase, putative 0.0757 0.1443 0.5438
Loa Loa (eye worm) hypothetical protein 0.035 0.0646 0.0918
Echinococcus multilocularis tachykinin peptides receptor 99D 0.5125 1 1
Onchocerca volvulus 0.0028 0.0015 0.0049
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0233 0.0418 0.8906
Schistosoma mansoni cathepsin F (C01 family) 0.1373 0.2651 0.3275
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0021
Onchocerca volvulus 0.0051 0.006 0.0219
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.003 0.0081
Brugia malayi Papain family cysteine protease containing protein 0.0757 0.1443 0.2053
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0081 0.012 0.0119
Onchocerca volvulus 0.0072 0.0102 0.0374
Entamoeba histolytica cysteine protease, putative 0.0336 0.0619 0.2328
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Echinococcus granulosus biogenic amine 5HT receptor 0.0072 0.0102 0.0101
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0336 0.0619 0.2372
Toxoplasma gondii ABC1 family protein 0.004 0.0039 0.0089
Trichomonas vaginalis calmodulin-2, putative 0.015 0.0255 0.0952
Schistosoma mansoni hypothetical protein 0.0403 0.0751 0.0926
Trypanosoma brucei protein I/6 0.015 0.0255 0.074
Onchocerca volvulus 0.0034 0.0028 0.0098
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0992 0.1904 0.2706
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Loa Loa (eye worm) cysteine protease 0.1373 0.2651 0.3771
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0039
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0046 0.0118
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0027 0.0037
Onchocerca volvulus 0.0154 0.0263 0.0982
Leishmania major small myristoylated protein 4, putative 0.0617 0.117 0.3426
Schistosoma mansoni cpg binding protein 0.0061 0.008 0.0095
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1373 0.2651 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0072 0.0102 0.0101
Giardia lamblia Cysteine protease 0.0336 0.0619 0.2372
Brugia malayi Cathepsin L-like precursor 0.1373 0.2651 0.3771
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni hypothetical protein 0.0034 0.0028 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0039 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0003 0.0003
Plasmodium vivax aspartyl proteinase, putative 0.0146 0.0246 0.0877
Echinococcus granulosus prefoldin subunit 6 0.0066 0.0091 0.009
Echinococcus granulosus lamin 0.0057 0.0073 0.0073
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0072 0.0102 0.0145
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.1059 0.2035 0.2035
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0043 0.0106
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.003 0.0081
Onchocerca volvulus 0.0155 0.0265 0.0991
Onchocerca volvulus 0.0028 0.0015 0.0049
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Plasmodium falciparum serine repeat antigen 3 0.0336 0.0619 0.2331
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0242 0.0435 0.0435
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Trypanosoma cruzi cysteine peptidase, putative 0.1761 0.3411 0.4849
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0008
Schistosoma mansoni hypothetical protein 0.0066 0.0091 0.011
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.003 0.0019 0.0027
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0743 0.1416 0.2011
Echinococcus multilocularis neuronal calcium sensor 0.015 0.0255 0.0254
Trypanosoma brucei I/6 autoantigen 0.015 0.0255 0.074
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.003 0.003
Plasmodium vivax metacaspase 1, putative 0.0044 0.0046 0.0118
Brugia malayi Fibulin-1 precursor 0.0029 0.0018 0.0025
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0129 0.0213 0.0303
Trypanosoma brucei calpain-like protein, putative 0.0965 0.1852 0.5426
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Mycobacterium ulcerans hypothetical protein 0.0081 0.012 1
Brugia malayi Matrixin family protein 0.0024 0.0009 0.0012
Giardia lamblia Cathepsin B precursor 0.0336 0.0619 0.2372
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0757 0.1443 0.2049
Leishmania major DNA polymerase eta, putative 0.0049 0.0058 0.0161
Schistosoma mansoni cathepsin F (C01 family) 0.1373 0.2651 0.3275
Trypanosoma brucei cysteine peptidase C (CPC) 0.1348 0.2602 0.7627
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0041 0.0146
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Leishmania major centrin, putative,caltractin, putative 0.015 0.0255 0.074
Entamoeba histolytica cysteine protease, putative 0.0336 0.0619 0.2328
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2366 0.4596 0.568
Echinococcus granulosus dro:myosuppressin receptor 0.0072 0.0102 0.0101
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0003 0.0004
Leishmania major trypanothione reductase 0.0102 0.0161 0.0465
Echinococcus granulosus caspase 0.0115 0.0186 0.0186
Onchocerca volvulus Putative cubilin 0.0026 0.0012 0.0036
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0026 0.0036
Leishmania major cathepsin L-like protease 0.1761 0.3411 1
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0091 0.0333
Schistosoma mansoni cpg binding protein 0.0061 0.008 0.0095
Trypanosoma cruzi kinesin, putative 0.0572 0.1082 0.1535
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0185 0.0644
Onchocerca volvulus 0.0057 0.0073 0.0268
Schistosoma mansoni hypothetical protein 0.0855 0.1636 0.202
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0089 0.0134 0.0163
Schistosoma mansoni inositol transporter 0.415 0.8089 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0336 0.0619 0.0763
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Onchocerca volvulus Peroxidasin homolog 0.011 0.0177 0.0658
Brugia malayi Cathepsin L-like precursor 0.1373 0.2651 0.3771
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0039 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.0032
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0227 0.0406 0.0573
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0336 0.0619 0.2291
Treponema pallidum NADH oxidase 0.0035 0.003 0.5
Entamoeba histolytica cysteine proteinase, putative 0.1373 0.2651 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.005
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0022 0.0031
Brugia malayi Cell death protein 3 precursor 0.0085 0.0127 0.018
Trypanosoma brucei hypothetical protein, conserved 0.0368 0.0681 0.1992
Trypanosoma cruzi metacaspase, putative 0.0044 0.0046 0.0062
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0081 0.012 0.0119
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Loa Loa (eye worm) hypothetical protein 0.015 0.0255 0.0362
Schistosoma mansoni cpg binding protein 0.0057 0.0073 0.0087
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.0449 0.0448
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0046
Schistosoma mansoni hypothetical protein 0.0393 0.0731 0.0901
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0393 0.0731 0.275
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0075 0.0108 0.0153
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.015 0.0255 0.0359
Echinococcus multilocularis microtubule associated protein 2 0.0682 0.1298 0.1297
Echinococcus multilocularis g-protein coupled receptor 0.0072 0.0102 0.0101
Trypanosoma brucei Calpain-like protein CALP1.3 0.062 0.1176 0.3442
Trypanosoma cruzi cysteine proteinase, putative 0.0757 0.1443 0.2049
Loa Loa (eye worm) calpain family protein 1 0.1644 0.3181 0.4525
Echinococcus granulosus enteropeptidase 0.0081 0.012 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0227 0.0406 0.0573
Brugia malayi hypothetical protein 0.0034 0.0027 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Schistosoma mansoni smad1 5 8 and 0.0025 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0052 0.0064 0.0179
Loa Loa (eye worm) hypothetical protein 0.003 0.0019 0.0026
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0094 0.0346
Loa Loa (eye worm) TK/ROR protein kinase 0.0066 0.0091 0.0129
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.1059 0.2035 0.7663
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.012 0.012
Onchocerca volvulus Cathepsin F homolog 0.1373 0.2651 1
Brugia malayi hypothetical protein 0.0034 0.0029 0.0041
Trypanosoma brucei caltractin, putative 0.0178 0.0309 0.09
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1173 0.2258 0.3209
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0458 0.0858 0.1219
Plasmodium vivax plasmepsin IV, putative 0.0146 0.0246 0.0877
Brugia malayi larval opioid receptor 0.0072 0.0102 0.0145
Giardia lamblia Calmodulin 0.0028 0.0015 0.0049
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0039 0.0774
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Brugia malayi Sodium:solute symporter family protein 0.1059 0.2035 0.2895
Plasmodium falciparum plasmepsin IV 0.0146 0.0246 0.0925
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0227 0.0406 0.1183
Echinococcus granulosus cathepsin l1 0.1373 0.2651 0.2651
Schistosoma mansoni hypothetical protein 0.0139 0.0233 0.0285
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0039 0.3087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0003 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis g protein coupled receptor 0.0072 0.0102 0.0101
Brugia malayi Dopamine receptor protein 2 0.0072 0.0102 0.0145
Plasmodium falciparum plasmepsin VII 0.0034 0.0029 0.0102
Plasmodium falciparum metacaspase-like protein 0.0044 0.0046 0.017
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0088 0.0134 0.0133
Plasmodium falciparum serine repeat antigen 5 0.0336 0.0619 0.2331
Brugia malayi aspartic protease BmAsp-2, identical 0.0034 0.0029 0.0041
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0012
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0139 0.0233 0.0232
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0336 0.0619 0.0763
Leishmania major prefoldin subunit, putative 0.0066 0.0091 0.0259
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0022 0.0025
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0007 0.001
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1341 0.2587 0.3677
Brugia malayi Trypsin family protein 0.0081 0.012 0.017
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.0102 0.0101
Entamoeba histolytica cysteine protease, putative 0.0336 0.0619 0.2328
Brugia malayi nuclear hormone receptor 0.0021 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0054
Schistosoma mansoni neuropeptide receptor 0.0072 0.0102 0.0123
Onchocerca volvulus Cell death protein 3 homolog 0.0085 0.0127 0.0469
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.015 0.0255 0.074
Leishmania major calmodulin, putative 0.015 0.0255 0.074
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0072 0.0102 0.0101
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Brugia malayi Cathepsin L-like precursor 0.0953 0.1827 0.2599
Echinococcus granulosus EF hand domain containing family member A2 0.015 0.0255 0.0254
Trichomonas vaginalis centrin, putative 0.015 0.0255 0.0952
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Leishmania major cathepsin L-like protease 0.1373 0.2651 0.7772
Plasmodium falciparum calpain 0.0393 0.0731 0.2753
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0233 0.0233
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1373 0.2651 1
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.009 0.0137 0.0166
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni chromobox protein 0.0068 0.0094 0.0113
Toxoplasma gondii subtilisin SUB12 0.0031 0.0022 0.0025
Echinococcus multilocularis neuropeptides capa receptor 0.0072 0.0102 0.0101
Plasmodium falciparum serine repeat antigen 2 0.0336 0.0619 0.2331
Toxoplasma gondii aspartyl protease 0.0034 0.0029 0.005
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0092 0.0131
Loa Loa (eye worm) calpain 5 0.0572 0.1082 0.1538
Trypanosoma brucei metacaspase MCA3 0.0044 0.0046 0.0128
Toxoplasma gondii cathepsin B 0.1348 0.2602 0.9813
Loa Loa (eye worm) hypothetical protein 0.0052 0.0064 0.009
Trypanosoma brucei calpain-like protein, putative 0.0965 0.1852 0.5426
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0072 0.0102 0.0123
Schistosoma mansoni neuropeptide F-like receptor 0.0072 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0066 0.0091 0.0129
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0288 0.0525 0.1532
Onchocerca volvulus Peroxidase homolog 0.011 0.0177 0.0658
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.001 0.001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0072 0.0102 0.0145
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0421 0.0785 0.1116
Echinococcus multilocularis EF hand domain containing family member A2 0.0154 0.0263 0.0262
Brugia malayi Eukaryotic aspartyl protease family protein 0.0034 0.0029 0.0041
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0288 0.0525 0.1532
Schistosoma mansoni biogenic amine (5HT) receptor 0.0072 0.0102 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0778 0.1485 0.2109
Loa Loa (eye worm) hypothetical protein 0.0034 0.0029 0.004
Trypanosoma cruzi small myristoylated protein 1-1 0.0392 0.0728 0.1032
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0531 0.1002 0.1422
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0421 0.0785 0.1116
Plasmodium vivax serine-repeat antigen (SERA) 0.0336 0.0619 0.2291
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0075 0.0108 0.0397
Plasmodium vivax proteasome subunit beta type-1, putative 0.0057 0.0073 0.0218
Leishmania major i/6 autoantigen-like protein 0.015 0.0255 0.074
Leishmania major calmodulin-like protein 0.015 0.0255 0.074
Echinococcus granulosus sodium:glucose cotransporter 2 0.415 0.8089 0.8089
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0012 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.0102 0.0101
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0039 0.3087
Echinococcus granulosus calpain 5 0.0965 0.1852 0.1851
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0072 0.0102 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0039
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.012 0.0145
Plasmodium falciparum glutathione reductase 0.0102 0.0161 0.0603
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0965 0.1852 0.5426
Brugia malayi cathepsin Z-like cysteine proteinase 0.0336 0.0619 0.0881
Plasmodium vivax aspartyl protease, putative 0.0034 0.0029 0.005
Echinococcus multilocularis serotonin receptor 0.0072 0.0102 0.0101
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Brugia malayi nuclear receptor NHR-88 0.0021 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0066 0.0091 0.0129
Plasmodium vivax serine-repeat antigen (SERA) 0.0336 0.0619 0.2291
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0046 0.0165
Entamoeba histolytica calpain large subunit domain III containing protein 0.0572 0.1082 0.4074
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0003 0.0004
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1253 0.2415 0.3433
Brugia malayi Heterochromatin protein 1 0.0068 0.0094 0.0134
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0393 0.0731 0.275
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0075 0.0108 0.013
Echinococcus granulosus alpha 1A adrenergic receptor 0.0072 0.0102 0.0101
Echinococcus granulosus microtubule associated protein 2 0.0682 0.1298 0.1297
Trypanosoma cruzi hypothetical protein, conserved 0.0368 0.0681 0.0966
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Echinococcus multilocularis neurocalcin 0.015 0.0255 0.0254
Echinococcus granulosus proteasome prosome macropain 0.0075 0.0108 0.0108
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Echinococcus granulosus Myosin regulatory light chain 0.0028 0.0015 0.0015
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.0751 0.0751
Loa Loa (eye worm) calpain D 0.0393 0.0731 0.1039
Onchocerca volvulus 0.0072 0.0102 0.0374
Plasmodium falciparum serine repeat antigen 4 0.0336 0.0619 0.2331
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.062 0.1176 0.1669
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0026 0.0087
Plasmodium falciparum pyruvate kinase 0.0033 0.0026 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0021
Brugia malayi Animal haem peroxidase family protein 0.011 0.0177 0.0251
Plasmodium falciparum cysteine proteinase falcipain 1 0.0757 0.1443 0.544
Schistosoma mansoni opsin-like receptor 0.0072 0.0102 0.0123
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0233 0.0418 0.8867
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0003 0.0002
Giardia lamblia Hypothetical protein 0.0066 0.0091 0.0339
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0022 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0336 0.0619 0.2328
Echinococcus granulosus g-protein coupled receptor 0.0072 0.0102 0.0101
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0233 0.0418 0.8906
Onchocerca volvulus 0.0521 0.0981 0.3696
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1373 0.2651 0.2651
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0039
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0153 0.0218
Schistosoma mansoni thyroid hormone receptor 0.016 0.0274 0.0336
Brugia malayi cathepsin L precursor 0.0336 0.0619 0.0881
Loa Loa (eye worm) hypothetical protein 0.0049 0.0058 0.0081
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Brugia malayi proteasome subunit beta type 1 0.0057 0.0073 0.0104
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Giardia lamblia Cathepsin L precursor 0.0336 0.0619 0.2372
Echinococcus granulosus caspase 8 0.0044 0.0046 0.0046
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0003 0.0002
Echinococcus granulosus high affinity choline transporter 1 0.1059 0.2035 0.2035
Echinococcus granulosus calcium uptake protein 1 0.0154 0.0263 0.0262
Onchocerca volvulus Chorion peroxidase homolog 0.011 0.0177 0.0658
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0054
Giardia lamblia Cathepsin B precursor 0.1348 0.2602 1
Loa Loa (eye worm) hypothetical protein 0.0242 0.0435 0.0618
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0041 0.0041
Echinococcus multilocularis musashi 0.0057 0.0073 0.0073
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0336 0.0619 0.0763
Loa Loa (eye worm) AStacin protease 0.0056 0.0071 0.01
Echinococcus granulosus histone lysine methyltransferase setb 0.0067 0.0092 0.0091
Giardia lamblia Cathepsin L precursor 0.0336 0.0619 0.2372
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0092 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0255 0.0952
Trypanosoma brucei calpain, putative 0.0681 0.1295 0.3791
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0046 0.0165
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0057 0.0073 0.0072
Trichomonas vaginalis calcium binding protein, putative 0.015 0.0255 0.0952
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0027 0.0034
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0046 0.0128
Loa Loa (eye worm) blistered cuticle protein 3 0.011 0.0177 0.0251
Echinococcus granulosus glycoprotein Antigen 5 0.0081 0.012 0.0119
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.003 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0757 0.1443 0.4226
Trichomonas vaginalis centrin, putative 0.0028 0.0015 0.0048
Leishmania major small myristoylated protein-2 0.0714 0.1359 0.398
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0342 0.0342
Onchocerca volvulus 0.0072 0.0102 0.0374
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0161 0.3402
Trypanosoma brucei calmodulin, putative 0.015 0.0255 0.074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0092 0.011
Brugia malayi Blistered cuticle protein 3 0.011 0.0177 0.0251
Entamoeba histolytica cysteine protease, putative 0.0336 0.0619 0.2328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Entamoeba histolytica calcium binding family protein 0.015 0.0255 0.0952
Schistosoma mansoni calmodulin 0.015 0.0255 0.0312
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.003 0.0109
Echinococcus granulosus neuropeptide FF receptor 2 0.0072 0.0102 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0039 0.0106
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0016
Schistosoma mansoni adenoreceptor 0.0072 0.0102 0.0123
Brugia malayi Muscleblind-like protein 0.015 0.0255 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0953 0.1827 0.689
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0026 0.0036
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Trypanosoma cruzi cysteine peptidase, putative 0.1373 0.2651 0.3769
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.1251 0.2411 0.3429
Brugia malayi MH2 domain containing protein 0.0025 0.001 0.0015
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0003 0.0004
Echinococcus granulosus programmed cell death protein 0.0178 0.0309 0.0309
Toxoplasma gondii hypothetical protein 0.0031 0.0022 0.0025
Echinococcus multilocularis EF hand domain containing family member A2 0.015 0.0255 0.0254
Brugia malayi Animal haem peroxidase family protein 0.011 0.0177 0.0251
Echinococcus multilocularis neuropeptide Y receptor 0.0072 0.0102 0.0101
Schistosoma mansoni high-affinity choline transporter 0.1059 0.2035 0.2513
Echinococcus multilocularis caspase 0.0115 0.0186 0.0186
Echinococcus multilocularis cathepsin b 0.3609 0.703 0.703
Echinococcus granulosus cathepsin L cysteine proteinase 0.1373 0.2651 0.2651
Onchocerca volvulus 0.0072 0.0102 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0146 0.0246 0.035
Onchocerca volvulus 0.1373 0.2651 1
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Trypanosoma brucei Component of motile flagella 41 0.015 0.0255 0.074
Trypanosoma cruzi unspecified product 0.0392 0.0728 0.1032
Trypanosoma cruzi hypothetical protein, conserved 0.0227 0.0406 0.0573
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.0611 0.0865
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0757 0.1443 0.2053
Brugia malayi glutathione reductase 0.0102 0.0161 0.0229
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0177 0.0251
Loa Loa (eye worm) hypothetical protein 0.0057 0.0073 0.0104
Brugia malayi calcium-binding protein 0.015 0.0255 0.0363
Echinococcus multilocularis fmrfamide receptor 0.0072 0.0102 0.0101
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0057 0.0073 0.0218
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0021
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.062 0.1176 0.3442
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0022 0.0025
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.062 0.1176 0.1669
Trypanosoma cruzi hypothetical protein, conserved 0.0227 0.0406 0.0573
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0075 0.0108 0.198
Plasmodium vivax hypothetical protein, conserved 0.0154 0.0263 0.0938
Entamoeba histolytica cysteine proteinase, putative 0.0757 0.1443 0.5438
Toxoplasma gondii aspartyl protease ASP1 0.0146 0.0246 0.0877
Toxoplasma gondii aspartyl protease ASP3 0.0034 0.0029 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0342 0.0342
Trypanosoma cruzi centrin-3 0.0178 0.0309 0.0436
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.015 0.0255 0.0359
Schistosoma mansoni DNA polymerase eta 0.0049 0.0058 0.0068
Onchocerca volvulus 0.0072 0.0102 0.0374
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.062 0.1176 0.1669
Trypanosoma brucei calpain-like protein, putative 0.1253 0.2415 0.708
Leishmania major cathepsin L-like protease 0.1373 0.2651 0.7772
Brugia malayi hypothetical protein 0.011 0.0177 0.0251
Plasmodium falciparum proteasome subunit beta type-5 0.0075 0.0108 0.0402
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus granulosus neuropeptide receptor A26 0.0072 0.0102 0.0101
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0259 0.0469 1
Trypanosoma cruzi cysteine protease, putative 0.0757 0.1443 0.2049
Onchocerca volvulus 0.0031 0.0022 0.0073
Echinococcus granulosus calpain A 0.237 0.4604 0.4603
Echinococcus multilocularis calbindin 32 0.0154 0.0263 0.0262
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0027 0.2044
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0617 0.117 0.1661
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0336 0.0619 0.2291
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0003 0.0002
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Trypanosoma cruzi calpain cysteine peptidase, putative 0.062 0.1176 0.1669
Brugia malayi beta-lactamase family protein 0.004 0.0039 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0336 0.0619 0.2328
Trypanosoma brucei trypanothione reductase 0.0102 0.0161 0.0465
Loa Loa (eye worm) MH2 domain-containing protein 0.0369 0.0683 0.0971
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0067 0.0092 0.029
Loa Loa (eye worm) EF hand family protein 0.015 0.0255 0.0362
Echinococcus granulosus sodium:myo inositol cotransporter 0.415 0.8089 0.8089
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis cathepsin L 0.0336 0.0619 0.0619
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Schistosoma mansoni calmodulin-related 0.0028 0.0015 0.0016
Onchocerca volvulus 0.0081 0.012 0.0442
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0046 0.0118
Echinococcus granulosus cathepsin l cysteine peptidase 0.1373 0.2651 0.2651
Schistosoma mansoni biogenic amine receptor 0.0072 0.0102 0.0123
Brugia malayi Cathepsin L-like precursor 0.0421 0.0785 0.1116
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Echinococcus granulosus sarcoplasmic calcium binding protein 0.015 0.0255 0.0254
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3609 0.703 0.869
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0336 0.0619 0.0763
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0227 0.0406 0.1183
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1253 0.2415 0.3433
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0227 0.0406 0.1183
Onchocerca volvulus 0.0031 0.0022 0.0073
Onchocerca volvulus 0.0031 0.0022 0.0073
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.088 0.1684 0.4934
Echinococcus granulosus somatostatin receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus granulosus fmrfamide receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.2216 0.4302 0.6119
Brugia malayi beta-lactamase 0.004 0.0039 0.0055
Brugia malayi Trypsin family protein 0.0081 0.012 0.017
Trypanosoma cruzi centrin, putative 0.0178 0.0309 0.0436
Echinococcus granulosus neuropeptide receptor 0.0072 0.0102 0.0101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Echinococcus granulosus calumenin 0.0154 0.0263 0.0262
Loa Loa (eye worm) acetyltransferase 0.0143 0.0241 0.0342
Echinococcus multilocularis lamin 0.0057 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.015 0.0255 0.0362
Loa Loa (eye worm) RecQ helicase 0.0024 0.0007 0.0009
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0039 0.0774
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0026 0.1965
Schistosoma mansoni hypothetical protein 0.0081 0.012 0.0145
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0965 0.1852 0.2631
Loa Loa (eye worm) G-protein coupled receptor 0.0072 0.0102 0.0144
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0336 0.0619 0.2291
Giardia lamblia Hypothetical protein 0.0336 0.0619 0.2372
Echinococcus granulosus pyruvate kinase 0.0033 0.0026 0.0025
Giardia lamblia Cathepsin L-like protease 0.0336 0.0619 0.2372
Toxoplasma gondii proteasome subunit beta type, putative 0.0075 0.0108 0.0351
Brugia malayi hypothetical protein 0.0081 0.012 0.017
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0254 0.0458 0.9763
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0093 0.0132
Echinococcus granulosus neuropeptide Y receptor 0.0072 0.0102 0.0101
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.003 0.0081
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1373 0.2651 0.2651
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0028 0.0015 0.0049
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Schistosoma mansoni neuropeptide receptor 0.0072 0.0102 0.0123
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.003 0.0034
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0115 0.0186 0.0186
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0336 0.0619 0.0763
Entamoeba histolytica calpain family cysteine protease, putative 0.0393 0.0731 0.275
Schistosoma mansoni peroxidasin 0.011 0.0177 0.0215
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.015 0.0255 0.0254
Brugia malayi Serotonin receptor 0.0072 0.0102 0.0145
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0242 0.0435 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0003 0.0004
Entamoeba histolytica cysteine protease, putative 0.1373 0.2651 1
Brugia malayi programmed cell death protein 6 0.015 0.0255 0.0363
Trichomonas vaginalis calcineurin B subunit, putative 0.0154 0.0263 0.0982
Onchocerca volvulus 0.0041 0.0041 0.0146
Loa Loa (eye worm) hypothetical protein 0.0393 0.0731 0.1039
Onchocerca volvulus 0.0034 0.0029 0.0098
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0003 0.0002
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0064 0.0179
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0332 0.0611 0.0865
Brugia malayi hypothetical protein 0.0052 0.0064 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0072 0.0102 0.0101
Onchocerca volvulus 0.011 0.0177 0.0658
Trichomonas vaginalis esterase, putative 0.004 0.0039 0.0136
Loa Loa (eye worm) myosin Light Chain family member 0.0032 0.0023 0.0032
Trichomonas vaginalis myosin light chain 1, putative 0.015 0.0255 0.0952
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus granulosus allatostatin A receptor 0.0072 0.0102 0.0101
Leishmania major cathepsin L-like protease 0.1373 0.2651 0.7772
Brugia malayi Papain family cysteine protease containing protein 0.0336 0.0619 0.0881
Brugia malayi calpain family protein 1 0.2216 0.4302 0.6119
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Mycobacterium leprae Probable lipase LipE 0.004 0.0039 0.0441
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0022 0.0031
Schistosoma mansoni amine GPCR 0.0072 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0129 0.0213 0.0302
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0094 0.0133
Leishmania major centrin, putative 0.015 0.0255 0.074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0092 0.011
Toxoplasma gondii calcium-dependent protein kinase 0.0154 0.0263 0.0938
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.0012 0.0017
Entamoeba histolytica grainin 2 0.0028 0.0015 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.0102 0.0123
Schistosoma mansoni Smad4 0.0025 0.001 0.001
Brugia malayi Serotonin receptor 0.0072 0.0102 0.0145
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0039 0.0774
Plasmodium falciparum thioredoxin reductase 0.0035 0.003 0.0109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0008 0.0021
Loa Loa (eye worm) neuropeptide F receptor 0.0072 0.0102 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0992 0.1904 0.558
Trichomonas vaginalis calmodulin, putative 0.0154 0.0263 0.0982
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0075 0.0108 0.0405
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0072 0.0102 0.0145
Giardia lamblia Pyruvate kinase 0.0033 0.0026 0.0088
Giardia lamblia Cathepsin B precursor 0.1348 0.2602 1
Plasmodium falciparum serine repeat antigen 6 0.0336 0.0619 0.2331
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0039 0.0038
Echinococcus granulosus cathepsin L 0.0336 0.0619 0.0619
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0242 0.0435 0.0535
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0227 0.0406 0.0573
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.0102 0.0123
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0233 0.0418 0.8906
Brugia malayi Cathepsin L-like precursor 0.1373 0.2651 0.3771
Echinococcus multilocularis calmodulin 0.015 0.0255 0.0254
Trichomonas vaginalis centrin, putative 0.0028 0.0015 0.0048
Schistosoma mansoni cathepsin D (A01 family) 0.043 0.0803 0.0989
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0336 0.0619 0.2328
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0342 0.042
Onchocerca volvulus Arrow homolog 0.0026 0.0012 0.0036
Toxoplasma gondii cathepsin CPC1 0.0336 0.0619 0.2291
Brugia malayi Matrixin family protein 0.0024 0.0009 0.0012
Echinococcus multilocularis smad 0.0025 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0003 0.0003
Plasmodium vivax centrin-1, putative 0.015 0.0255 0.0909
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0003 0.0002
Echinococcus granulosus calpain 7 C02 family 0.0965 0.1852 0.1851
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.0161 0.0161
Toxoplasma gondii EF hand domain-containing protein 0.015 0.0255 0.0909
Plasmodium vivax aspartyl protease, putative 0.0034 0.0029 0.005
Brugia malayi calpain 7 0.0965 0.1852 0.2634
Trypanosoma cruzi cysteine proteinase, putative 0.0757 0.1443 0.2049
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0046 0.0165
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0177 0.0251
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.015 0.0255 0.0952
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0003 0.0002
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1348 0.2602 0.7627
Toxoplasma gondii hypothetical protein 0.0393 0.0731 0.2715
Onchocerca volvulus 0.1373 0.2651 1
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0227 0.0406 0.1183
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0075 0.0108 0.0397
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0393 0.0731 0.275
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Echinococcus multilocularis neuropeptide FF receptor 2 0.0072 0.0102 0.0101
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0039 0.0774
Echinococcus multilocularis orexin receptor type 2 0.0072 0.0102 0.0101
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0092 0.0111
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0992 0.1904 0.558
Giardia lamblia Encystation-specific protease 0.0336 0.0619 0.2372
Echinococcus granulosus sodium:glucose cotransporter 0.415 0.8089 0.8089
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0015 0.0048
Schistosoma mansoni neuronal calcium sensor 0.015 0.0255 0.0312
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0039 0.0136
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.015 0.0255 0.0359
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0064 0.0235
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0072 0.0102 0.0123
Plasmodium vivax unspecified product 0.0336 0.0619 0.2291
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0003 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0332 0.0611 0.1785
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0153 0.0218
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Entamoeba histolytica cysteine proteinase 2 0.0757 0.1443 0.5438
Trypanosoma cruzi prefoldin subunit, putative 0.0066 0.0091 0.0125
Plasmodium falciparum metacaspase 1 0.0044 0.0046 0.017
Entamoeba histolytica grainin, putative 0.0154 0.0263 0.0982
Trichomonas vaginalis caltractin, putative 0.0028 0.0015 0.0048
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0028 0.0015 0.0048
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Leishmania major cathepsin L-like protease 0.1373 0.2651 0.7772
Echinococcus multilocularis Myosin regulatory light chain 0.0028 0.0015 0.0015
Schistosoma mansoni calpain-7 (C02 family) 0.0965 0.1852 0.2287
Echinococcus granulosus 7tm_1 domain containing protein 0.0072 0.0102 0.0101
Echinococcus multilocularis sex peptide receptor 0.0072 0.0102 0.0101
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0006 0.0013
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.003 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Brugia malayi KE2 family protein 0.0066 0.0091 0.0129
Plasmodium falciparum plasmepsin X 0.0034 0.0029 0.0102
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0681 0.1295 0.3791
Leishmania major hypothetical protein, conserved 0.0227 0.0406 0.1183
Loa Loa (eye worm) Smad1 0.0025 0.001 0.0014
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0026 0.0149
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0072 0.0102 0.0101
Leishmania major hypothetical protein, conserved 0.004 0.0039 0.0106
Echinococcus multilocularis pyruvate kinase 0.0026 0.0012 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0073 0.0104
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0036 0.0125
Loa Loa (eye worm) hypothetical protein 0.0421 0.0785 0.1116
Trypanosoma cruzi cruzipain precursor, putative 0.1761 0.3411 0.4849
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Mycobacterium leprae conserved hypothetical protein 0.004 0.0039 0.0441
Trypanosoma brucei antigen, putative 0.0965 0.1852 0.5426
Loa Loa (eye worm) hypothetical protein 0.015 0.0255 0.0362
Entamoeba histolytica prefoldin subunit 6, putative 0.0066 0.0091 0.0333
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0064 0.0087
Echinococcus granulosus cathepsin b 0.3609 0.703 0.703
Giardia lamblia Cathepsin B precursor 0.1348 0.2602 1
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0094 0.0346
Brugia malayi beta-lactamase family protein 0.004 0.0039 0.0055
Entamoeba histolytica calmodulin, putative 0.015 0.0255 0.0952
Brugia malayi G protein-coupled receptor 0.0072 0.0102 0.0145
Mycobacterium tuberculosis Conserved protein 0.004 0.0039 0.0774
Echinococcus multilocularis calmodulin 0.015 0.0255 0.0254
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1373 0.2651 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0992 0.1904 0.558
Schistosoma mansoni rab 0.015 0.0255 0.0312
Schistosoma mansoni hypothetical protein 0.0031 0.0022 0.0024
Plasmodium vivax SET domain protein, putative 0.0067 0.0092 0.029
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0259 0.0469 1
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0039 0.0136
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0026 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0336 0.0619 0.2328
Trichomonas vaginalis calpain, putative 0.0393 0.0731 0.275
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0022 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Schistosoma mansoni calpain (C02 family) 0.0965 0.1852 0.2287
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1373 0.2651 1
Echinococcus multilocularis serotonin receptor 0.0072 0.0102 0.0101
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0022 0.0025
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.015 0.0255 0.074
Loa Loa (eye worm) neuropeptide F receptor 0.0072 0.0102 0.0144
Loa Loa (eye worm) hypothetical protein 0.0029 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0336 0.0619 0.088
Brugia malayi cathepsin L-like cysteine proteinase 0.0336 0.0619 0.0881
Plasmodium falciparum plasmepsin VI 0.0146 0.0246 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Onchocerca volvulus 0.1373 0.2651 1
Onchocerca volvulus 0.003 0.002 0.0064
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Echinococcus multilocularis high affinity choline transporter 1 0.1059 0.2035 0.2035
Echinococcus granulosus chromobox protein 1 0.0068 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0368 0.0681 0.2563
Schistosoma mansoni neuropeptide receptor 0.0072 0.0102 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0003 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0022 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Brugia malayi Papain family cysteine protease containing protein 0.0336 0.0619 0.0881
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0008 0.0021
Leishmania major receptor-type adenylate cyclase a-like protein 0.0227 0.0406 0.1183
Trypanosoma cruzi prefoldin subunit, putative 0.0066 0.0091 0.0125
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0036 0.0132
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0992 0.1904 0.558
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Brugia malayi chromobox protein homolog 3 0.0038 0.0036 0.0051
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.0102 0.0101
Onchocerca volvulus 0.0057 0.0073 0.0268
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0081
Loa Loa (eye worm) aspartyl protease 6 0.0034 0.0029 0.004
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0026 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.1761 0.3411 0.4849
Leishmania major calpain family cysteine protease-like protein 0.062 0.1176 0.3442
Echinococcus granulosus sex peptide receptor 0.0072 0.0102 0.0101
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0153 0.0218
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0022 0.0025
Schistosoma mansoni amine GPCR 0.0072 0.0102 0.0123
Brugia malayi Papain family cysteine protease containing protein 0.0336 0.0619 0.0881
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0046 0.0062
Loa Loa (eye worm) hypothetical protein 0.015 0.0255 0.0362
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0022 0.0021
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0177 0.0251
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.003 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0233 0.0418 0.8906
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.0102 0.0101
Brugia malayi G-protein coupled receptor 0.0072 0.0102 0.0145
Loa Loa (eye worm) matrixin family protein 0.0059 0.0076 0.0107
Schistosoma mansoni neuropeptide F-like receptor 0.0072 0.0102 0.0123
Echinococcus granulosus neuropeptide s receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0342 0.0342
Brugia malayi Animal haem peroxidase family protein 0.011 0.0177 0.0251
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0039 0.0037 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0336 0.0619 0.2331
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Echinococcus multilocularis G protein coupled receptor 139 0.0072 0.0102 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0046 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Echinococcus granulosus transmembrane protease serine 3 0.0081 0.012 0.0119
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0072 0.0102 0.0101
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0007 0.0007
Trypanosoma brucei centrin-3 0.0178 0.0309 0.09
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0336 0.0619 0.0763
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0081 0.012 0.017
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0072 0.0102 0.0123
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0072 0.0102 0.0145
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0393 0.0731 0.2715
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0027 0.007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0336 0.0619 0.088
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Loa Loa (eye worm) hypothetical protein 0.0953 0.1827 0.2599
Brugia malayi GH02984p 0.1059 0.2035 0.2895
Trichomonas vaginalis kakapo, putative 0.0028 0.0015 0.0048
Onchocerca volvulus 0.1373 0.2651 1
Plasmodium falciparum prefoldin subunit 6, putative 0.0066 0.0091 0.0337
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.003 0.0107
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0259 0.0469 1
Echinococcus multilocularis sodium:myo inositol cotransporter 0.415 0.8089 0.8089
Mycobacterium ulcerans beta-lactamase 0.004 0.0039 0.3087
Plasmodium vivax prefoldin subunit 6, putative 0.0066 0.0091 0.0286
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0081 0.012 0.0119
Entamoeba histolytica cysteine protease, putative 0.0336 0.0619 0.2328
Loa Loa (eye worm) hypothetical protein 0.1644 0.3181 0.4525
Brugia malayi calpain family protein 1 0.2216 0.4302 0.6119
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0012 0.0017
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Brugia malayi hypothetical protein 0.0072 0.0102 0.0145
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0072 0.0102 0.0123
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Onchocerca volvulus 0.0024 0.0009 0.0023
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0965 0.1852 0.2631
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0029 0.0037
Toxoplasma gondii microneme protein MIC4 0.0031 0.0022 0.0025
Schistosoma mansoni smad1 5 8 and 0.0025 0.001 0.001
Loa Loa (eye worm) beta-lactamase 0.004 0.0039 0.0054
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0081 0.012 0.0145
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1253 0.2415 0.708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0336 0.0619 0.2328
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0026 0.0036
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0067 0.0092 0.0091
Echinococcus granulosus cpg binding protein 0.0061 0.008 0.0079
Leishmania major phospholipase c-like protein 0.015 0.0255 0.074
Entamoeba histolytica protein kinase, putative 0.0572 0.1082 0.4074
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.015 0.0255 0.0952
Leishmania major META domain containing protein 0.0227 0.0406 0.1183
Echinococcus granulosus Tolloid protein 1 0.009 0.0137 0.0136
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0146 0.0246 0.092
Trypanosoma cruzi metacaspase, putative 0.0044 0.0046 0.0062
Trypanosoma brucei centrin, putative 0.015 0.0255 0.074
Leishmania major programmed cell death 6 protein-like protein 0.015 0.0255 0.074
Schistosoma mansoni thyroid hormone receptor 0.016 0.0274 0.0336
Onchocerca volvulus 0.1059 0.2035 0.7674
Loa Loa (eye worm) hypothetical protein 0.0072 0.0102 0.0144
Echinococcus multilocularis lamin dm0 0.0057 0.0073 0.0073
Trichomonas vaginalis calcineurin B subunit, putative 0.015 0.0255 0.0952
Echinococcus granulosus EF HAND 1 calcium binding site 0.015 0.0255 0.0254
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0024 0.0009 0.0007
Schistosoma mansoni opsin-like receptor 0.0072 0.0102 0.0123
Schistosoma mansoni neuropeptide f receptor 76f 0.0072 0.0102 0.0123
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1373 0.2651 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1348 0.2602 0.3214
Entamoeba histolytica hypothetical protein, conserved 0.0154 0.0263 0.0982
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1373 0.2651 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0336 0.0619 0.088
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.001 0.001
Brugia malayi cathepsin B-like cysteine proteinase 0.3609 0.703 1
Loa Loa (eye worm) hypothetical protein 0.0953 0.1827 0.2599
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0039 0.0054
Loa Loa (eye worm) hypothetical protein 0.0034 0.0029 0.004
Brugia malayi Tachykinin-like peptides receptor 99D 0.0072 0.0102 0.0145
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0016
Onchocerca volvulus 0.0031 0.0022 0.0073
Toxoplasma gondii troponin c, isotype gamma, putative 0.015 0.0255 0.0909
Plasmodium falciparum plasmepsin II 0.0146 0.0246 0.0925
Entamoeba histolytica hypothetical protein 0.0336 0.0619 0.2328
Schistosoma mansoni hypothetical protein 0.0072 0.0102 0.0123
Schistosoma mansoni hypothetical protein 0.015 0.0255 0.0312
Echinococcus multilocularis somatostatin receptor 0.0072 0.0102 0.0101
Trypanosoma brucei mitochondrial calcium uptake 1 0.015 0.0255 0.074
Loa Loa (eye worm) cathepsin B 0.1348 0.2602 0.3701
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0007 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0003 0.0004
Onchocerca volvulus 0.0031 0.0022 0.0073
Leishmania major pyruvate kinase 0.0033 0.0026 0.0067
Trypanosoma brucei centrin, putative 0.015 0.0255 0.074
Echinococcus granulosus muscleblind protein 0.015 0.0255 0.0254
Echinococcus granulosus laminin 0.0029 0.0018 0.0017
Loa Loa (eye worm) calmodulin-like protein 0.015 0.0255 0.0362
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1253 0.2415 0.708
Schistosoma mansoni cathepsin B (C01 family) 0.0336 0.0619 0.0763
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0241 0.0343
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0026 0.0087
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.003 0.2372
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.003 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0288 0.0525 0.1532
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3609 0.703 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0393 0.0731 0.275
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1729 0.3347 0.3347
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.003 0.0081
Brugia malayi calpain 5 0.0393 0.0731 0.104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1761 0.3411 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0072 0.0102 0.0145
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.003 0.0019 0.0349
Trichomonas vaginalis calmodulin, putative 0.015 0.0255 0.0952
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0057 0.0073 0.0265
Echinococcus granulosus dna polymerase eta 0.0049 0.0058 0.0057
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Echinococcus granulosus neuropeptide receptor 0.0072 0.0102 0.0101
Brugia malayi Pre-SET motif family protein 0.0067 0.0092 0.013
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0057 0.0073 0.0087
Schistosoma mansoni sodium/solute symporter 0.1059 0.2035 0.2513
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0336 0.0619 0.2291
Loa Loa (eye worm) melatonin receptor type 1A 0.0072 0.0102 0.0144
Echinococcus multilocularis sodium:glucose cotransporter 2 0.415 0.8089 0.8089
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0031
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2216 0.4302 0.5317
Schistosoma mansoni cercarial elastase (S01 family) 0.0081 0.012 0.0145
Echinococcus granulosus orexin receptor type 2 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0067 0.0093 0.0131
Echinococcus granulosus G protein coupled receptor 139 0.0072 0.0102 0.0101
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0332 0.0611 0.1785
Leishmania major hypothetical protein, conserved 0.0227 0.0406 0.1183
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0021 0.003
Trichomonas vaginalis hypothetical protein 0.0393 0.0731 0.275
Echinococcus multilocularis calpain 5 0.0965 0.1852 0.1851
Leishmania major hypothetical protein, conserved 0.0066 0.0091 0.026
Brugia malayi PAN domain containing protein 0.0031 0.0022 0.0031
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0015 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0091 0.0126
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0063 0.0085 0.0121
Loa Loa (eye worm) TYRA-2 protein 0.0072 0.0102 0.0144
Brugia malayi neuropeptide F receptor 0.0072 0.0102 0.0145
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Loa Loa (eye worm) bone morphogenetic protein 1b 0.009 0.0137 0.0194
Echinococcus granulosus smad 0.0025 0.001 0.001
Echinococcus granulosus g protein coupled receptor 0.0072 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0003 0.0003
Echinococcus multilocularis peroxidasin 0.011 0.0177 0.0176
Loa Loa (eye worm) hypothetical protein 0.0336 0.0619 0.088
Leishmania major hypothetical protein, conserved 0.0368 0.0681 0.1992
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0003 0.0003
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0336 0.0619 0.2372
Echinococcus granulosus EF hand domain containing family member A2 0.0154 0.0263 0.0262
Echinococcus multilocularis chromobox protein 1 0.0068 0.0094 0.0094
Brugia malayi intermediate filament protein 0.0057 0.0073 0.0105
Brugia malayi Cytochrome P450 family protein 0.0033 0.0027 0.0038
Schistosoma mansoni caspase-7 (C14 family) 0.0085 0.0127 0.0154
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0022 0.0021
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0003 0.0003
Echinococcus granulosus calpain 0.0965 0.1852 0.1851
Entamoeba histolytica cysteine protease, putative 0.0757 0.1443 0.5438
Entamoeba histolytica cysteine proteinase, putative 0.0953 0.1827 0.689
Schistosoma mansoni calpain-7 (C02 family) 0.0965 0.1852 0.2287
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0073 0.0103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0342 0.042
Schistosoma mansoni amine GPCR 0.0072 0.0102 0.0123
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0029 0.0032
Brugia malayi RasGEF domain containing protein 0.0028 0.0015 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0028 0.004
Trypanosoma cruzi conserved protein 0.063 0.1195 0.1696
Brugia malayi Cathepsin L-like precursor 0.0953 0.1827 0.2599
Echinococcus granulosus cathepsin L 0.0757 0.1443 0.1443
Echinococcus granulosus neuropeptides capa receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0146 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.011 0.0177 0.0251
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0169
Schistosoma mansoni hypothetical protein 0.0081 0.012 0.0145
Leishmania major calcineurin B subunit, putative 0.015 0.0255 0.074
Brugia malayi hypothetical protein 0.0155 0.0265 0.0377
Loa Loa (eye worm) transcription factor SMAD2 0.0369 0.0683 0.0971
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.003 0.0039
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.0012 0.0017
Trypanosoma brucei Calpain-like protein 1.2 0.0778 0.1485 0.4349
Onchocerca volvulus 0.1373 0.2651 1
Echinococcus granulosus tar DNA binding protein 0.0067 0.0092 0.0092
Onchocerca volvulus 0.0078 0.0114 0.0419
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.0102 0.0123
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.001 0.0014
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0992 0.1904 0.2706
Echinococcus granulosus centrin 2 0.015 0.0255 0.0254
Brugia malayi TAR-binding protein 0.0067 0.0092 0.0131
Onchocerca volvulus 0.0081 0.012 0.0442
Trypanosoma brucei hypothetical protein, conserved 0.015 0.0255 0.074
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0027 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0092 0.0111
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0046 0.0165
Schistosoma mansoni growth hormone secretagogue receptor 0.0072 0.0102 0.0123
Trypanosoma brucei proteasome beta 6 subunit 0.0057 0.0073 0.0206
Echinococcus multilocularis programmed cell death protein 6 0.0032 0.0023 0.0023
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0026 0.0087
Schistosoma mansoni hypothetical protein 0.015 0.0255 0.0312
Trypanosoma cruzi I/6 autoantigen, putative 0.015 0.0255 0.0359
Loa Loa (eye worm) proteasome subunit beta type 1 0.0057 0.0073 0.0103
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0227 0.0406 0.1183
Echinococcus granulosus g protein coupled receptor 0.0072 0.0102 0.0101
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0067 0.0092 0.0091
Toxoplasma gondii EFHC1, putative 0.015 0.0255 0.0909
Leishmania major kinesin, putative 0.0572 0.1082 0.3166
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.015 0.0255 0.0952
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0336 0.0619 0.2291

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4.597 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.202 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.171 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.156 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.125 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.106 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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