Detailed information for compound 31976

Basic information

Technical information
  • TDR Targets ID: 31976
  • Name: (3,5-dimethylphenyl)methyl N-[(2S)-1-[[(2S,3R ,4R)-3-hydroxy-5-[[(2S)-1-[(2-hydroxy-4-metho xyphenyl)methylamino]-3-methyl-1-oxobutan-2-y l]amino]-4-[(4-methoxyphenyl)methylamino]-5-o xo-1-phenylpentan-2-yl]amino]-3,3-dimethyl-1- oxobutan-2-yl]carbamate
  • MW: 854.042 | Formula: C48H63N5O9
  • H donors: 7 H acceptors: 6 LogP: 7.47 Rotable bonds: 26
    Rule of 5 violations (Lipinski): 3
  • SMILES: COc1ccc(cc1)CN[C@H]([C@@H]([C@@H](NC(=O)[C@H](C(C)(C)C)NC(=O)OCc1cc(C)cc(c1)C)Cc1ccccc1)O)C(=O)N[C@H](C(=O)NCc1ccc(cc1O)OC)C(C)C
  • InChi: 1S/C48H63N5O9/c1-29(2)40(44(56)50-27-35-17-20-37(61-9)25-39(35)54)52-45(57)41(49-26-33-15-18-36(60-8)19-16-33)42(55)38(24-32-13-11-10-12-14-32)51-46(58)43(48(5,6)7)53-47(59)62-28-34-22-30(3)21-31(4)23-34/h10-23,25,29,38,40-43,49,54-55H,24,26-28H2,1-9H3,(H,50,56)(H,51,58)(H,52,57)(H,53,59)/t38-,40-,41+,42+,43+/m0/s1
  • InChiKey: PMOFZDZWFGYUBB-KNENSWBYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (3,5-dimethylphenyl)methyl N-[(1S)-1-[[(1S,2R,3R)-1-benzyl-2-hydroxy-4-[[(1S)-1-[(2-hydroxy-4-methoxy-phenyl)methylcarbamoyl]-2-methyl-propyl]amino]-3-[(4-methoxyphenyl)methylamino]-4-oxo-butyl]carbamoyl]-2,2-dimethyl-propyl]carbamate
  • N-[(1S)-1-[[[(1S,2R,3R)-1-benzyl-2-hydroxy-4-[[(1S)-1-[[(2-hydroxy-4-methoxyphenyl)methylamino]-oxomethyl]-2-methylpropyl]amino]-3-[(4-methoxyphenyl)methylamino]-4-oxobutyl]amino]-oxomethyl]-2,2-dimethylpropyl]carbamic acid (3,5-dimethylphenyl)methyl ester
  • (3,5-dimethylphenyl)methyl N-[(2S)-1-[[(2S,3R,4R)-3-hydroxy-5-[[(2S)-1-[(2-hydroxy-4-methoxy-phenyl)methylamino]-3-methyl-1-oxo-butan-2-yl]amino]-4-[(4-methoxyphenyl)methylamino]-5-oxo-1-phenyl-pentan-2-yl]amino]-3,3-dimethyl-1-oxo-butan-2-yl]carbamate
  • N-[(1S)-1-[[(1S,2R,3R)-1-benzyl-2-hydroxy-4-[[(1S)-1-[(2-hydroxy-4-methoxy-benzyl)carbamoyl]-2-methyl-propyl]amino]-4-keto-3-(p-anisylamino)butyl]carbamoyl]-2,2-dimethyl-propyl]carbamic acid (3,5-dimethylbenzyl) ester
  • (3,5-dimethylphenyl)methyl N-[(1S)-1-[[(1S,2R,3R)-2-hydroxy-4-[[(1S)-1-[(2-hydroxy-4-methoxy-phenyl)methylcarbamoyl]-2-methyl-propyl]amino]-3-[(4-methoxyphenyl)methylamino]-4-oxo-1-(phenylmethyl)butyl]carbamoyl]-2,2-dimethyl-propyl]carbamate
  • N-[(1S)-1-[[[(1S,2R,3R)-2-hydroxy-4-[[(1S)-1-[[(2-hydroxy-4-methoxyphenyl)methylamino]-oxomethyl]-2-methylpropyl]amino]-3-[(4-methoxyphenyl)methylamino]-4-oxo-1-(phenylmethyl)butyl]amino]-oxomethyl]-2,2-dimethylpropyl]carbamic acid (3,5-dimethylphenyl)methyl ester
  • N-[(1S)-1-[[(1S,2R,3R)-1-(benzyl)-2-hydroxy-4-[[(1S)-1-[(2-hydroxy-4-methoxy-benzyl)carbamoyl]-2-methyl-propyl]amino]-4-keto-3-[(4-methoxybenzyl)amino]butyl]carbamoyl]-2,2-dimethyl-propyl]carbamic acid (3,5-dimethylbenzyl) ester
  • AIDS-022432
  • AIDS022432
  • {(S)-1-[(1S,2S,3R)-1-Benzyl-2-hydroxy-3-[(S)-1-(2-hydroxy-4-methoxy-benzylcarbamoyl)-2-methyl-propylcarbamoyl]-3-(4-methoxy-benzylamino)-propylcarbamoyl]-2,2-dimethyl-propyl}-carbamic acid 3,5-dimethyl-benzyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni histamine h1 receptor 0.0189 0.0302 0.0363
Loa Loa (eye worm) transcriptional regulator 0.0033 0.0003 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0179 0.0215
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0016 0.0043
Toxoplasma gondii thioredoxin reductase 0.0104 0.014 0.0406
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Echinococcus granulosus calbindin 32 0.02 0.0322 0.0321
Toxoplasma gondii calcium binding protein precursor, putative 0.0034 0.0006 0.0012
Schistosoma mansoni caspase-3 (C14 family) 0.0114 0.0158 0.0189
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.01 0.0132 0.0159
Loa Loa (eye worm) DEAH box polypeptide 35 0.0033 0.0004 0.0005
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0012 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0431 0.0764 0.2261
Schistosoma mansoni myosin xvIII 0.0189 0.0302 0.0363
Brugia malayi fibroinase precursor 0.0431 0.0764 0.0922
Trichomonas vaginalis conserved hypothetical protein 0.0364 0.0637 0.1884
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0016 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0012 0.0013
Plasmodium falciparum proteasome subunit beta type-5 0.0159 0.0245 0.0716
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.005 0.0037 0.0041
Echinococcus multilocularis caspase 0.0114 0.0158 0.0157
Schistosoma mansoni cpg binding protein 0.0093 0.0118 0.0142
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0164 0.0255 0.0752
Schistosoma mansoni calpain (C02 family) 0.1248 0.2325 0.2806
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0089 0.011 0.0317
Trichomonas vaginalis calmodulin-2, putative 0.0195 0.0313 0.0926
Brugia malayi prolyl oligopeptidase family protein 0.008 0.0093 0.0112
Leishmania major cathepsin L-like protease 0.1797 0.3374 0.8045
Schistosoma mansoni lamin 0.0058 0.0051 0.0061
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0027 0.0033
Entamoeba histolytica calpain family cysteine protease, putative 0.0476 0.0851 0.2514
Leishmania major cathepsin L-like protease 0.2226 0.4194 1
Plasmodium falciparum plasmepsin VIII, putative 0.0052 0.004 0.0108
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0042 0.0116
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0476 0.0851 0.2519
Mycobacterium tuberculosis Probable peptidase 0.0303 0.0519 0.4167
Echinococcus multilocularis cathepsin b 0.4366 0.8281 0.8281
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Trichomonas vaginalis calpain, putative 0.0476 0.0851 0.2519
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1023 0.1894 0.4513
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0037 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Echinococcus granulosus proteasome prosome macropain 0.0159 0.0245 0.0243
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0141 0.021 0.0209
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0329 0.0568 0.0684
Mycobacterium tuberculosis Probable dehydrogenase 0.0238 0.0394 0.3165
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0027 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Echinococcus granulosus cathepsin b 0.4366 0.8281 0.8281
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.0764 0.0921
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0137 0.0201 0.0242
Echinococcus multilocularis Dipeptidyl peptidase 9 0.008 0.0093 0.0092
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0189 0.0302 0.03
Mycobacterium leprae PROBABLE HYDROLASE 0.0101 0.0133 0.2542
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0037 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0037 0.0045
Brugia malayi hypothetical protein 0.0109 0.0149 0.018
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi Myosin regulatory light chain 1 0.0034 0.0006 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0315 0.0378
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Brugia malayi Peroxidasin 0.0109 0.0149 0.018
Mycobacterium tuberculosis Conserved protein 0.0039 0.0016 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Echinococcus multilocularis calpain 7 (C02 family) 0.1248 0.2325 0.2324
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.001 0.006
Schistosoma mansoni reticulocalbin 0.0195 0.0313 0.0377
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Toxoplasma gondii cathepsin B 0.1648 0.3089 0.9153
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0149 0.018
Treponema pallidum NADH oxidase 0.0036 0.001 0.5
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0682 0.1243 0.2961
Schistosoma mansoni cathepsin S (C01 family) 0.0431 0.0764 0.0921
Schistosoma mansoni ef hand domain family member A2 0.0195 0.0313 0.0377
Plasmodium falciparum cysteine repeat modular protein 1 0.0089 0.011 0.0317
Trypanosoma brucei centrin, putative 0.0195 0.0313 0.0742
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0238 0.0394 0.3165
Plasmodium vivax plasmepsin IV, putative 0.0164 0.0255 0.0746
Trypanosoma cruzi I/6 autoantigen, putative 0.0195 0.0313 0.0375
Loa Loa (eye worm) blistered cuticle protein 3 0.0109 0.0149 0.018
Schistosoma mansoni hypothetical protein 0.0032 0.0003 0.0002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0001 0.0001
Toxoplasma gondii troponin c, isotype gamma, putative 0.0195 0.0313 0.0922
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0037 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0037 0.0045
Echinococcus multilocularis prolyl endopeptidase 0.0761 0.1394 0.1393
Plasmodium falciparum metacaspase-like protein 0.0043 0.0023 0.0057
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0033 0.0003 0.0001
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0012 0.0011
Toxoplasma gondii microneme protein MIC17C 0.0045 0.0027 0.0073
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.107 0.1984 0.4728
Plasmodium vivax vivapain-1 0.0985 0.1822 0.5396
Loa Loa (eye worm) hypothetical protein 0.1243 0.2316 0.2797
Onchocerca volvulus 0.0189 0.0302 0.0893
Echinococcus multilocularis tissue type plasminogen activator 0.0089 0.011 0.0109
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0225 0.037 0.0877
Echinococcus multilocularis dnaJ subfamily B 0.0821 0.151 0.1509
Echinococcus granulosus g protein coupled receptor 0.0189 0.0302 0.03
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0225 0.037 0.0444
Trypanosoma cruzi major cysteine proteinase, putative 0.0431 0.0764 0.092
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0033 0.0003 0.0002
Onchocerca volvulus 0.0058 0.0051 0.0151
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0022 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0189 0.0302 0.03
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0196 0.0315 0.038
Echinococcus granulosus muscleblind protein 0.0155 0.0236 0.0235
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0189 0.0302 0.0364
Trypanosoma cruzi major cysteine proteinase, putative 0.086 0.1583 0.1909
Schistosoma mansoni neuropeptide F-like receptor 0.0189 0.0302 0.0363
Trypanosoma cruzi cysteine protease, putative 0.0985 0.1822 0.2198
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0012 0.0015
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0017 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0071 0.0086
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1533 0.2869 0.3463
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0033 0.0003 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0189 0.0302 0.03
Entamoeba histolytica cysteine proteinase, putative 0.1243 0.2316 0.6861
Loa Loa (eye worm) myosin Light Chain family member 0.0039 0.0015 0.0018
Echinococcus multilocularis lamin 0.0058 0.0051 0.005
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0034 0.0075
Echinococcus multilocularis serotonin receptor 0.0189 0.0302 0.03
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0189 0.0302 0.0893
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0016 0.0043
Schistosoma mansoni alpha-1 adrenergic receptor 0.0189 0.0302 0.0363
Echinococcus granulosus centrin 2 0.0195 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.019 0.0303 0.0366
Loa Loa (eye worm) glutathione reductase 0.0104 0.014 0.0169
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0315 0.0313
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0613 0.1112 0.1341
Toxoplasma gondii centrin family protein 0.0034 0.0006 0.0012
Schistosoma mansoni rab 0.0195 0.0313 0.0377
Schistosoma mansoni amine GPCR 0.0189 0.0302 0.0363
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0235 0.039 0.0389
Brugia malayi Fibulin-1 precursor 0.0072 0.0079 0.0096
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1797 0.3374 1
Trypanosoma brucei small myristoylated protein 1-1 0.0388 0.0682 0.162
Echinococcus multilocularis allatostatin A receptor 0.0189 0.0302 0.03
Echinococcus multilocularis neuropeptide FF receptor 2 0.0189 0.0302 0.03
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Trichomonas vaginalis hypothetical protein 0.0476 0.0851 0.2519
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0037 0.0045
Echinococcus granulosus g protein coupled receptor 0.0189 0.0302 0.03
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0019
Leishmania major receptor-type adenylate cyclase a-like protein 0.0225 0.037 0.0877
Plasmodium vivax SET domain protein, putative 0.0125 0.0179 0.0522
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0431 0.0764 0.2256
Echinococcus granulosus orexin receptor type 2 0.0189 0.0302 0.03
Echinococcus granulosus enteropeptidase 0.0123 0.0176 0.0175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0093 0.0112
Echinococcus granulosus hypothetical protein 0.0189 0.0302 0.03
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0123 0.0176 0.0211
Leishmania major cathepsin L-like protease 0.1797 0.3374 0.8045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0022 0.0055
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0189 0.0302 0.03
Giardia lamblia Cathepsin B precursor 0.0431 0.0764 0.2465
Loa Loa (eye worm) hypothetical protein 0.4366 0.8281 1
Toxoplasma gondii prefoldin subunit 6, putative 0.0066 0.0067 0.0192
Onchocerca volvulus Peroxidase homolog 0.0109 0.0149 0.0441
Leishmania major hypothetical protein, conserved 0.0364 0.0637 0.1513
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0985 0.1822 0.2199
Entamoeba histolytica calcium binding family protein 0.0195 0.0313 0.092
Brugia malayi calpain 7 0.1248 0.2325 0.2807
Onchocerca volvulus 0.1722 0.3231 0.9576
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0023 0.006
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0149 0.018
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0303 0.0519 0.0623
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.0051
Brugia malayi hypothetical protein 0.0038 0.0012 0.0015
Echinococcus granulosus programmed cell death protein 6 0.0039 0.0015 0.0014
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0123 0.0176 0.0211
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0315 0.0378
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1533 0.2869 0.3463
Giardia lamblia Cathepsin L precursor 0.0431 0.0764 0.2465
Brugia malayi ORL1-like opioid receptor 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Trichomonas vaginalis calcium binding protein, putative 0.0195 0.0313 0.0926
Onchocerca volvulus 0.0045 0.0027 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1453 0.2717 0.3279
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.001 0.0017
Echinococcus granulosus Tolloid protein 1 0.0197 0.0317 0.0316
Schistosoma mansoni calmodulin 0.0195 0.0313 0.0377
Toxoplasma gondii hypothetical protein 0.0045 0.0027 0.0073
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0016 0.0256
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0037 0.0044
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0189 0.0302 0.03
Brugia malayi Cathepsin L-like precursor 0.1797 0.3374 0.4075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0033 0.0003 0.0004
Entamoeba histolytica grainin, putative 0.02 0.0322 0.0945
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1533 0.2869 0.684
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Schistosoma mansoni mitochondrial solute carrier 0.0195 0.0313 0.0377
Echinococcus multilocularis g protein coupled receptor 0.0189 0.0302 0.03
Onchocerca volvulus Matrilysin homolog 0.0184 0.0292 0.0863
Mycobacterium leprae Probable lipase LipE 0.0039 0.0016 0.0263
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0225 0.037 0.0444
Trypanosoma brucei calpain-like protein, putative 0.1248 0.2325 0.5541
Loa Loa (eye worm) hypothetical protein 0.0125 0.0179 0.0216
Brugia malayi CXXC zinc finger family protein 0.0088 0.0109 0.0131
Echinococcus granulosus acylamino acid releasing enzyme 0.008 0.0093 0.0092
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0315 0.0313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0315 0.0378
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0015
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0195 0.0313 0.0375
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0431 0.0764 0.2465
Onchocerca volvulus 0.0189 0.0302 0.0893
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0195 0.0313 0.0312
Schistosoma mansoni centrin 0.0195 0.0313 0.0377
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.001 0.0019
Onchocerca volvulus Putative cubilin 0.0042 0.0021 0.0061
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0189 0.0302 0.03
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0037 0.0045
Trypanosoma cruzi prefoldin subunit, putative 0.0066 0.0067 0.0078
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0016 0.0109
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1797 0.3374 0.3374
Echinococcus multilocularis tumor protein p63 0.0334 0.0579 0.0578
Echinococcus multilocularis cathepsin b 0.4366 0.8281 0.8281
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Plasmodium vivax unspecified product 0.0985 0.1822 0.5396
Echinococcus multilocularis neuropeptide receptor 0.0189 0.0302 0.03
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.008 0.0093 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0195 0.0313 0.0926
Brugia malayi Thioredoxin family protein 0.007 0.0075 0.009
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0141 0.021 0.062
Mycobacterium ulcerans transglutaminase family protein 0.007 0.0075 0.1399
Schistosoma mansoni neuronal calcium sensor 0.0195 0.0313 0.0377
Schistosoma mansoni calmodulin-related 0.0034 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0117 0.0165 0.0198
Loa Loa (eye worm) hypothetical protein 0.0083 0.0099 0.0119
Entamoeba histolytica calmodulin, putative 0.0034 0.0006 0.0009
Brugia malayi Cytochrome P450 family protein 0.0108 0.0148 0.0178
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.3165 0.5988 0.5987
Schistosoma mansoni cytochrome P450 0.0032 0.0003 0.0002
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1533 0.2869 0.684
Mycobacterium ulcerans hypothetical protein 0.007 0.0075 0.1399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.107 0.1984 0.2394
Trichomonas vaginalis calcium binding protein, putative 0.0195 0.0313 0.0926
Loa Loa (eye worm) hypothetical protein 0.1243 0.2316 0.2797
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0431 0.0764 0.0922
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0037 0.0045
Loa Loa (eye worm) calpain D 0.0476 0.0851 0.1027
Loa Loa (eye worm) proteasome subunit beta type 2 0.005 0.0037 0.0044
Mycobacterium ulcerans hypothetical protein 0.0123 0.0176 0.3356
Brugia malayi Blistered cuticle protein 3 0.0109 0.0149 0.018
Brugia malayi Cytochrome P450 family protein 0.0068 0.0071 0.0086
Trypanosoma cruzi oligopeptidase b 0.0303 0.0519 0.0623
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0006 0.0004
Brugia malayi Cathepsin L-like precursor 0.1797 0.3374 0.4075
Echinococcus multilocularis calpain 5 0.1248 0.2325 0.2324
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0041
Schistosoma mansoni calmodulin 0.0195 0.0313 0.0377
Trichomonas vaginalis centrin, putative 0.0034 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0019
Brugia malayi Cathepsin L-like precursor 0.1797 0.3374 0.4075
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0023 0.0064
Onchocerca volvulus 0.1243 0.2316 0.6863
Plasmodium vivax aspartyl proteinase, putative 0.0164 0.0255 0.0746
Echinococcus multilocularis glycoprotein Antigen 5 0.0123 0.0176 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0023 0.0064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0125 0.018 0.0217
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.008 0.0093 0.0269
Echinococcus granulosus calumenin 0.02 0.0322 0.0321
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0065 0.0077
Loa Loa (eye worm) hypothetical protein 0.0478 0.0854 0.1031
Leishmania major cathepsin L-like protease 0.1797 0.3374 0.8045
Echinococcus granulosus Transglutaminase 0.007 0.0075 0.0074
Brugia malayi chromobox protein homolog 3 0.004 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0089 0.011 0.0133
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.001 0.0021
Onchocerca volvulus Dual oxidase homolog 0.0109 0.0149 0.0441
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0238 0.0394 0.3165
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0761 0.1394 0.1682
Brugia malayi hypothetical protein 0.0052 0.004 0.0048
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0042 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.005 0.0037 0.0035
Schistosoma mansoni adenoreceptor 0.0189 0.0302 0.0363
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0001 0.0001
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0431 0.0764 0.0921
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Echinococcus granulosus Dipeptidyl peptidase 9 0.008 0.0093 0.0092
Trypanosoma cruzi conserved protein 0.0711 0.1299 0.1566
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0034 0.0006 0.0009
Toxoplasma gondii aspartyl protease ASP1 0.0164 0.0255 0.0748
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0037 0.0036
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1797 0.3374 1
Onchocerca volvulus 0.0088 0.0109 0.0321
Echinococcus granulosus lamin 0.0058 0.0051 0.005
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0037 0.0045
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0164 0.0255 0.0306
Leishmania major hypothetical protein, conserved 0.0225 0.037 0.0877
Onchocerca volvulus 0.0189 0.0302 0.0893
Brugia malayi G protein-coupled receptor 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0066 0.0068 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) hypothetical protein 0.0155 0.0236 0.0286
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0101 0.0133 0.1059
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis G-protein coupled receptor, putative 0.0189 0.0302 0.03
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0264 0.0445 0.8575
Onchocerca volvulus 0.0034 0.0006 0.0018
Toxoplasma gondii microneme protein MIC4 0.0045 0.0027 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0195 0.0313 0.0926
Brugia malayi Serotonin receptor 0.0189 0.0302 0.0364
Plasmodium falciparum plasmepsin IX 0.0052 0.004 0.0108
Brugia malayi Hemopexin family protein 0.0117 0.0165 0.0199
Echinococcus multilocularis calmodulin 0.0195 0.0313 0.0312
Trypanosoma cruzi cysteine peptidase, putative 0.2226 0.4194 0.5063
Plasmodium vivax serine-repeat antigen (SERA) 0.0431 0.0764 0.2256
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0027 0.0033
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1648 0.3089 0.7364
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0189 0.0302 0.0363
Echinococcus granulosus calpain 5 0.1248 0.2325 0.2324
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0125 0.018 0.0217
Onchocerca volvulus 0.0045 0.0027 0.0079
Echinococcus granulosus tumor protein p63 0.0334 0.0579 0.0578
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0179 0.0215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Leishmania major DNA polymerase eta, putative 0.0049 0.0034 0.0075
Loa Loa (eye worm) G-protein coupled receptor 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Leishmania major hypothetical protein, conserved 0.0195 0.0313 0.0742
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0065 0.0077
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0128 0.0184 0.0183
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0123 0.0176 0.0175
Toxoplasma gondii calmodulin CAM2 0.0034 0.0006 0.0012
Echinococcus granulosus sodium channel protein 0.0039 0.0015 0.0014
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0431 0.0764 0.2256
Mycobacterium tuberculosis Probable reductase 0.0238 0.0394 0.3165
Brugia malayi Serotonin receptor 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Loa Loa (eye worm) hypothetical protein 0.0066 0.0067 0.0081
Echinococcus multilocularis calpain 0.1248 0.2325 0.2324
Brugia malayi Trypsin family protein 0.0123 0.0176 0.0212
Schistosoma mansoni inositol monophosphatase 0.0036 0.0009 0.001
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0012 0.0013
Onchocerca volvulus 0.0189 0.0302 0.0893
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0431 0.0764 0.0922
Onchocerca volvulus 0.0049 0.0034 0.01
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.0075 0.0586
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.001 0.0017
Plasmodium falciparum plasmepsin VII 0.0052 0.004 0.0108
Plasmodium falciparum plasmepsin I 0.0164 0.0255 0.0746
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0021
Echinococcus multilocularis g protein coupled receptor 0.0189 0.0302 0.03
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0022 0.0057
Trypanosoma cruzi metacaspase, putative 0.0043 0.0023 0.0024
Brugia malayi EF hand family protein 0.02 0.0322 0.0389
Trypanosoma brucei conserved protein 0.0234 0.0389 0.0921
Trypanosoma brucei prefoldin subunit, putative 0.0066 0.0067 0.0155
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Loa Loa (eye worm) calmodulin-like protein 0.0195 0.0313 0.0378
Echinococcus granulosus cathepsin L cysteine proteinase 0.1797 0.3374 0.3374
Mycobacterium tuberculosis Probable oxidoreductase 0.0264 0.0445 0.3573
Onchocerca volvulus Neuropeptide F receptor homolog 0.0189 0.0302 0.0893
Brugia malayi cathepsin F-like cysteine proteinase 0.0554 0.0999 0.1206
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0485 0.0583
Giardia lamblia Cathepsin L precursor 0.0431 0.0764 0.2465
Brugia malayi NAD-dependent deacetylase SIRT1 0.0141 0.021 0.0254
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0009 0.0025
Brugia malayi RasGEF domain containing protein 0.0034 0.0006 0.0008
Trypanosoma brucei calpain-like protein, putative 0.1533 0.2869 0.684
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0009
Brugia malayi Papain family cysteine protease containing protein 0.0431 0.0764 0.0922
Schistosoma mansoni egf-like domain protein 0.0066 0.0068 0.008
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0123 0.0176 0.0211
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0016 0.0043
Giardia lamblia Hypothetical protein 0.02 0.0322 0.1033
Loa Loa (eye worm) calpain 0.1248 0.2325 0.2807
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0164 0.0255 0.0748
Schistosoma mansoni biogenic amine receptor 0.0189 0.0302 0.0363
Brugia malayi hypothetical protein 0.031 0.0532 0.0642
Loa Loa (eye worm) hypothetical protein 0.0083 0.0099 0.0119
Mycobacterium ulcerans Sir2-like regulatory protein 0.0033 0.0003 0.0015
Trichomonas vaginalis calmodulin, putative 0.02 0.0322 0.0951
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0431 0.0764 0.2256
Echinococcus multilocularis caspase 3 0.0071 0.0076 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0083 0.0099 0.0119
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0038 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0195 0.0313 0.0375
Trypanosoma brucei centrin, putative 0.0195 0.0313 0.0742
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0149 0.018
Trypanosoma brucei proteasome subunit beta type-2, putative 0.005 0.0037 0.0081
Echinococcus multilocularis Transglutaminase 0.007 0.0075 0.0074
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Echinococcus multilocularis G protein coupled receptor 139 0.0189 0.0302 0.03
Loa Loa (eye worm) AStacin protease 0.0115 0.0161 0.0194
Brugia malayi G protein-coupled receptor F59B2.13 0.0189 0.0302 0.0364
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0431 0.0764 0.2256
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.0071 0.0086
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0037 0.0036
Schistosoma mansoni peptidylglycine monooxygenase 0.0125 0.018 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0016 0.0016
Mycobacterium ulcerans proteasome PrcB 0.0159 0.0245 0.4691
Toxoplasma gondii cathepsin CPL 0.1797 0.3374 1
Toxoplasma gondii EFHC1, putative 0.0195 0.0313 0.0922
Schistosoma mansoni hypothetical protein 0.0068 0.0071 0.0085
Onchocerca volvulus 0.0123 0.0176 0.0519
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Echinococcus multilocularis hypothetical protein 0.1248 0.2325 0.2324
Mycobacterium tuberculosis Conserved protein 0.007 0.0075 0.0586
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4366 0.8281 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.001 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0431 0.0764 0.2261
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0023 0.006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1695 0.3179 0.3178
Trichomonas vaginalis calpain, putative 0.0476 0.0851 0.2519
Loa Loa (eye worm) neuropeptide F receptor 0.0189 0.0302 0.0364
Schistosoma mansoni memapsin-2 (A01 family) 0.0461 0.0821 0.099
Loa Loa (eye worm) hypothetical protein 0.0235 0.039 0.0471
Onchocerca volvulus 0.0123 0.0176 0.0519
Echinococcus granulosus tm gpcr rhodopsin 0.0189 0.0302 0.03
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0189 0.0302 0.03
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0003 0.0003
Giardia lamblia Cathepsin B precursor 0.1648 0.3089 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0189 0.0302 0.0363
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0037 0.0109
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0858 0.1579 0.3761
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0012 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0329 0.0568 0.0684
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.001 1
Echinococcus multilocularis calcyphosin protein 0.0034 0.0006 0.0005
Echinococcus granulosus caspase 2 0.0083 0.0099 0.0098
Leishmania major calmodulin, putative 0.0195 0.0313 0.0742
Onchocerca volvulus 0.0189 0.0302 0.0893
Giardia lamblia Hypothetical protein 0.0431 0.0764 0.2465
Brugia malayi beta-lactamase family protein 0.0039 0.0016 0.0019
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0012 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0016 0.0016
Brugia malayi cytochrome P450 0.0032 0.0003 0.0003
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.001 0.0019
Brugia malayi hypothetical protein 0.004 0.0017 0.002
Echinococcus multilocularis programmed cell death protein 0.023 0.0379 0.0378
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0017
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0431 0.0764 0.0921
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0033
Brugia malayi Probable ATP-dependent helicase DHX35 0.0033 0.0004 0.0005
Giardia lamblia Cathepsin B precursor 0.0431 0.0764 0.2465
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0012 0.0011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0023 0.0066
Onchocerca volvulus 0.0189 0.0302 0.0893
Entamoeba histolytica calmodulin, putative 0.0195 0.0313 0.092
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0012 0.0013
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0034 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0052 0.004 0.0048
Schistosoma mansoni opsin-like receptor 0.0189 0.0302 0.0363
Trypanosoma cruzi calmodulin, putative 0.0195 0.0313 0.0375
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.008 0.0093 0.0092
Entamoeba histolytica cysteine proteinase 1, putative 0.0985 0.1822 0.5396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1243 0.2316 0.6863
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0189 0.0302 0.0363
Schistosoma mansoni chromatin regulatory protein sir2 0.0033 0.0003 0.0003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.001 0.0137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.107 0.1984 0.4728
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0195 0.0313 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0033
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0045 0.0027 0.0073
Loa Loa (eye worm) calpain family protein 1 0.297 0.5615 0.6781
Echinococcus multilocularis calumenin 0.02 0.0322 0.0321
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0701 0.128 0.1544
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0037 0.0045
Brugia malayi Trypsin family protein 0.0123 0.0176 0.0212
Trypanosoma cruzi oligopeptidase b 0.0303 0.0519 0.0623
Entamoeba histolytica cysteine proteinase, putative 0.0985 0.1822 0.5396
Loa Loa (eye worm) acetyltransferase 0.0144 0.0216 0.0261
Brugia malayi Cathepsin L-like precursor 0.1797 0.3374 0.4075
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0033 0.0003 0.0007
Brugia malayi prolyl oligopeptidase family protein 0.008 0.0093 0.0112
Loa Loa (eye worm) proteasome subunit beta type 1 0.0122 0.0175 0.0211
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1453 0.2717 0.6477
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0701 0.128 0.1544
Loa Loa (eye worm) hypothetical protein 0.2199 0.4141 0.5001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.001 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0329 0.0568 0.135
Trypanosoma brucei Metacaspase-4 0.0043 0.0023 0.0048
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0149 0.018
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.0206 0.0247
Loa Loa (eye worm) ctsf protein 0.1797 0.3374 0.4075
Trypanosoma brucei metacaspase MCA2 0.0043 0.0023 0.0048
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4366 0.8281 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0209 0.0208
Mycobacterium ulcerans putative transglutaminase-like protein 0.007 0.0075 0.1399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0189 0.0302 0.0363
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0431 0.0764 0.2256
Leishmania major small myristoylated protein-1 0.0388 0.0682 0.162
Toxoplasma gondii preprocathepsin c precursor, putative 0.0431 0.0764 0.2258
Echinococcus granulosus dro:myosuppressin receptor 0.0189 0.0302 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0033
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0701 0.128 0.3049
Leishmania major hypothetical protein, conserved 0.0711 0.1299 0.3093
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0037 0.0043
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0701 0.128 0.3049
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.001 0.0009
Onchocerca volvulus 0.0089 0.011 0.0325
Leishmania major centrin, putative 0.0195 0.0313 0.0742
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Schistosoma mansoni hypothetical protein 0.0097 0.0127 0.0152
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Schistosoma mansoni amine GPCR 0.0189 0.0302 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0985 0.1822 0.5399
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0225 0.037 0.0877
Leishmania major hypothetical protein, conserved 0.0225 0.037 0.0877
Echinococcus granulosus Calcium binding protein 0.0034 0.0006 0.0005
Trypanosoma brucei mitochondrial calcium uptake 1 0.0195 0.0313 0.0742
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0195 0.0313 0.0312
Toxoplasma gondii calmodulin CAM1 0.02 0.0322 0.0947
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0823 0.1512 0.1824
Trypanosoma brucei centrin-3 0.023 0.0379 0.0899
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0431 0.0764 0.2261
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0037 0.0036
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus granulosus serotonin receptor 0.0189 0.0302 0.03
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0303 0.0519 1
Echinococcus granulosus cathepsin l1 0.1243 0.2316 0.2315
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0033 0.0003 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.0764 0.0921
Brugia malayi Trypsin family protein 0.0123 0.0176 0.0212
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0431 0.0764 0.2465
Schistosoma mansoni neuropeptide f receptor 76f 0.0189 0.0302 0.0363
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0189 0.0302 0.03
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0037 0.0045
Giardia lamblia Hypothetical protein 0.0066 0.0067 0.0208
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0485 0.1151
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Loa Loa (eye worm) histone methyltransferase 0.0032 0.0001 0.0002
Brugia malayi larval opioid receptor 0.0189 0.0302 0.0364
Giardia lamblia Cysteine protease 0.0431 0.0764 0.2465
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0476 0.0851 0.2519
Echinococcus granulosus dnaJ subfamily B 0.0821 0.151 0.1509
Onchocerca volvulus 0.0189 0.0302 0.0893
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0042 0.0119
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0012 0.0011
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.001 0.0009
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0216 0.0215
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0114 0.0158 0.0157
Brugia malayi intermediate filament protein 0.0058 0.0051 0.0062
Onchocerca volvulus Cathepsin F homolog 0.1797 0.3374 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Onchocerca volvulus 0.0244 0.0407 0.1206
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0017
Schistosoma mansoni chromatin regulatory protein sir2 0.0128 0.0184 0.0221
Echinococcus granulosus microtubule associated protein 2 0.1336 0.2494 0.2493
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0238 0.0394 0.3165
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3165 0.5988 0.7231
Giardia lamblia Cathepsin B precursor 0.0431 0.0764 0.2465
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Loa Loa (eye worm) hypothetical protein 0.0554 0.0999 0.1206
Schistosoma mansoni neuronal calcium sensor 0.0195 0.0313 0.0377
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0033 0.0003 0.0002
Entamoeba histolytica dipeptidyl-peptidase, putative 0.008 0.0093 0.0266
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0033 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0016 0.0043
Brugia malayi Muscleblind-like protein 0.0155 0.0236 0.0286
Leishmania major hypothetical protein, conserved 0.0225 0.037 0.0877
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Schistosoma mansoni cpg binding protein 0.0088 0.0109 0.013
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0189 0.0302 0.0364
Echinococcus granulosus calcium uptake protein 1 0.02 0.0322 0.0321
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0159 0.0245 0.4695
Echinococcus granulosus beta-adrenergic receptor kinase 0.0038 0.0012 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Trichomonas vaginalis peptide N-glycanase, putative 0.007 0.0075 0.0218
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0159 0.0245 0.0578
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0189 0.0302 0.03
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0027 0.0033
Toxoplasma gondii microneme protein MIC17A 0.0045 0.0027 0.0073
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0189 0.0302 0.03
Loa Loa (eye worm) MH2 domain-containing protein 0.0254 0.0426 0.0514
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0012 0.0033
Loa Loa (eye worm) cytochrome P450 family protein 0.0108 0.0148 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0037 0.0045
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0015 0.0035
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0009
Trypanosoma brucei cysteine peptidase, putative 0.0701 0.128 0.3049
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0037 0.0036
Toxoplasma gondii cathepsin CPC1 0.0431 0.0764 0.2258
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0128 0.0184 0.0219
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0189 0.0302 0.0363
Schistosoma mansoni calpain C (C02 family) 0.1248 0.2325 0.2806
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0038 0.0012 0.0027
Echinococcus granulosus EF hand domain containing family member A2 0.02 0.0322 0.0321
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0068 0.0071 0.1332
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1533 0.2869 0.684
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0285 0.0485 0.1151
Trypanosoma brucei Calpain-like protein 2 0.0838 0.1542 0.3673
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0132 0.0159
Echinococcus granulosus neuropeptide FF receptor 2 0.0189 0.0302 0.03
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.008 0.0093 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0431 0.0764 0.2261
Echinococcus granulosus intermediate filament protein 0.0058 0.0051 0.005
Onchocerca volvulus 0.1797 0.3374 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0189 0.0302 0.0363
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.0764 0.0921
Brugia malayi prolyl oligopeptidase family protein 0.008 0.0093 0.0112
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.037 0.0444
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0034 0.0041
Echinococcus multilocularis cathepsin L 0.0431 0.0764 0.0763
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0264 0.0445 0.3573
Trypanosoma cruzi cysteine peptidase, putative 0.0554 0.0999 0.1204
Plasmodium falciparum plasmepsin VI 0.0164 0.0255 0.0746
Onchocerca volvulus 0.0052 0.004 0.0117
Onchocerca volvulus 0.0039 0.0016 0.0045
Loa Loa (eye worm) prolyl oligopeptidase 0.008 0.0093 0.0112
Leishmania major small myristoylated protein 4, putative 0.0611 0.1109 0.2639
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.126 0.2349 0.2835
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0169 0.3222
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0431 0.0764 0.2256
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0123 0.0176 0.0211
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0104 0.014 0.1109
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0859 0.1582 0.191
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0016 0.0015
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0431 0.0764 0.2256
Brugia malayi Cathepsin L-like cysteine proteinase 0.1243 0.2316 0.2797
Loa Loa (eye worm) hypothetical protein 0.0052 0.004 0.0048
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.001 0.001
Trypanosoma cruzi metacaspase, putative 0.0043 0.0023 0.0024
Leishmania major hypothetical protein, unknown function 0.0476 0.0851 0.2024
Plasmodium falciparum serine repeat antigen 7 0.0431 0.0764 0.2256
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0122 0.0175 0.0514
Echinococcus multilocularis neuropeptide Y receptor 0.0189 0.0302 0.03
Echinococcus multilocularis geminin 0.0858 0.1581 0.158
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0195 0.0313 0.0926
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0037 0.0036
Schistosoma mansoni chromatin regulatory protein sir2 0.0141 0.021 0.0252
Brugia malayi prolyl oligopeptidase family protein 0.0761 0.1394 0.1683
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0003 0.0003
Brugia malayi Papain family cysteine protease containing protein 0.0431 0.0764 0.0922
Loa Loa (eye worm) hypothetical protein 0.0034 0.0006 0.0008
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0476 0.0851 0.2519
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Trypanosoma brucei calpain-like protein, putative 0.1248 0.2325 0.5541
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0017 0.0047
Plasmodium vivax vivapain-2 0.1797 0.3374 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0009
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0051 0.0062
Loa Loa (eye worm) hypothetical protein 0.1797 0.3374 0.4075
Schistosoma mansoni thyroid hormone receptor 0.0188 0.03 0.0361
Plasmodium vivax vivapain-3 0.0985 0.1822 0.5396
Leishmania major calmodulin-like protein 0.0195 0.0313 0.0742
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0189 0.0302 0.03
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0037 0.0044
Brugia malayi calcium-binding protein 0.0195 0.0313 0.0378
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0065 0.0078
Schistosoma mansoni hypothetical protein 0.007 0.0075 0.0089
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0159 0.0245 0.1956
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0022 0.0061
Echinococcus multilocularis Tolloid protein 1 0.0197 0.0317 0.0316
Plasmodium falciparum serine repeat antigen 3 0.0431 0.0764 0.2256
Trypanosoma brucei caltractin, putative 0.023 0.0379 0.0899
Onchocerca volvulus 0.031 0.0532 0.1575
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0016 0.0018
Echinococcus multilocularis cathepsin L cysteine protease 0.1797 0.3374 0.3374
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.1722 0.3231 0.3902
Loa Loa (eye worm) TYRA-2 protein 0.0189 0.0302 0.0364
Schistosoma mansoni calpain-7 (C02 family) 0.1248 0.2325 0.2806
Brugia malayi calpain family protein 1 0.297 0.5615 0.6781
Brugia malayi neuropeptide F receptor 0.0189 0.0302 0.0364
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0122 0.0175 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0012 0.0015
Leishmania major META domain containing protein 0.0225 0.037 0.0877
Trichomonas vaginalis calcineurin B subunit, putative 0.0195 0.0313 0.0926
Echinococcus granulosus Myosin regulatory light chain 0.0034 0.0006 0.0005
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Brugia malayi Tachykinin-like peptides receptor 99D 0.0189 0.0302 0.0364
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0761 0.1395 0.3323
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0093 0.0273
Loa Loa (eye worm) hypothetical protein 0.0088 0.0109 0.0132
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0431 0.0764 0.2256
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0149 0.018
Entamoeba histolytica calmodulin, putative 0.0195 0.0313 0.092
Echinococcus multilocularis beta adrenergic receptor kinase 0.0038 0.0012 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0109 0.0131
Entamoeba histolytica cysteine protease, putative 0.0431 0.0764 0.2256
Brugia malayi Matrixin family protein 0.0083 0.0099 0.0119
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0149 0.018
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0012 0.0011
Echinococcus multilocularis chromobox protein 1 0.0071 0.0077 0.0076
Brugia malayi Dopamine receptor 0.0189 0.0302 0.0364
Giardia lamblia Cysteine protease 0.0431 0.0764 0.2465
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0038 0.0012 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Schistosoma mansoni calmodulin related calcium binding protein 0.0195 0.0313 0.0377
Plasmodium falciparum thioredoxin reductase 0.0036 0.001 0.0019
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0122 0.0175 0.051
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0197 0.0317 0.0382
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0189 0.0302 0.0363
Echinococcus granulosus peroxidasin 0.0109 0.0149 0.0148
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0761 0.1395 0.3323
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0225 0.037 0.0877
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0033 0.0003 0.0002
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0195 0.0313 0.092
Plasmodium vivax hypothetical protein, conserved 0.008 0.0093 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0037 0.0044
Plasmodium falciparum plasmepsin III 0.0052 0.004 0.0108
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0023 0.0057
Brugia malayi calpain 5 0.0771 0.1414 0.1708
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Plasmodium vivax aspartyl proteinase, putative 0.0052 0.004 0.0108
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0016 0.0043
Entamoeba histolytica cysteine protease, putative 0.0431 0.0764 0.2256
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Echinococcus granulosus g-protein coupled receptor 0.0189 0.0302 0.03
Brugia malayi cathepsin Z-like cysteine proteinase 0.0431 0.0764 0.0922
Brugia malayi Pepsin A precursor 0.0052 0.004 0.0048
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.008 0.0093 0.0269
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0122 0.0175 0.0508
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0189 0.0302 0.03
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0123 0.0176 0.0175
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0038 0.0012 0.0015
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0196 0.0315 0.038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0068 0.0071 0.0086
Echinococcus multilocularis serotonin receptor 0.0189 0.0302 0.03
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0009 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0159 0.0245 0.0294
Giardia lamblia Cathepsin L precursor 0.0431 0.0764 0.2465
Echinococcus multilocularis programmed cell death protein 6 0.0039 0.0015 0.0014
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0037 0.0106
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0016 0.0263
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1533 0.2869 0.3463
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0128 0.0184 0.0543
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1248 0.2325 0.2805
Onchocerca volvulus 0.0117 0.0165 0.0488
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Brugia malayi Neuronal calcium sensor family protein 1 0.0034 0.0006 0.0008
Trypanosoma brucei trypanothione reductase 0.0104 0.014 0.0327
Schistosoma mansoni Mername-AA248 (C02 family) 0.1248 0.2325 0.2806
Echinococcus granulosus G protein coupled receptor 139 0.0189 0.0302 0.03
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.001 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1648 0.3089 0.3729
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Leishmania major hypothetical protein, conserved 0.0225 0.037 0.0877
Trypanosoma cruzi centrin, putative 0.023 0.0379 0.0455
Echinococcus granulosus alpha 1A adrenergic receptor 0.0189 0.0302 0.03
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0003 0.0003
Echinococcus multilocularis proteasome (prosome, macropain) 0.0159 0.0245 0.0243
Plasmodium vivax aspartyl protease, putative 0.0052 0.004 0.0108
Onchocerca volvulus 0.004 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0083 0.0099 0.0119
Leishmania major cathepsin L-like protease 0.1797 0.3374 0.8045
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0012 0.0013
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0009 0.0025
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0012 0.0015
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0189 0.0302 0.0364
Brugia malayi KE2 family protein 0.0066 0.0067 0.0081
Echinococcus multilocularis neuropeptide s receptor 0.0189 0.0302 0.03
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0189 0.0302 0.0364
Toxoplasma gondii proteasome subunit beta type 2, putative 0.005 0.0037 0.0101
Plasmodium vivax calpain, putative 0.1248 0.2325 0.6886
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Echinococcus multilocularis neurocalcin 0.0195 0.0313 0.0312
Entamoeba histolytica grainin 2 0.023 0.0379 0.1115
Onchocerca volvulus 0.0195 0.0313 0.0927
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0189 0.0302 0.03
Brugia malayi Cathepsin L-like precursor 0.0554 0.0999 0.1206
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0043 0.0023 0.0027
Mycobacterium tuberculosis Hypothetical protein 0.007 0.0075 0.0586
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0216 0.026
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0477 0.0852 0.2026
Plasmodium falciparum serine repeat antigen 1 0.0431 0.0764 0.2256
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0593 0.1074 0.1294
Schistosoma mansoni cathepsin B (C01 family) 0.0431 0.0764 0.0921
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0037 0.0045
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0009 0.0132
Trypanosoma brucei prolyl oligopeptidase, putative 0.0303 0.0519 0.1231
Onchocerca volvulus 0.0189 0.0302 0.0893
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Loa Loa (eye worm) programmed cell death protein 6 0.02 0.0322 0.0389
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Echinococcus multilocularis neuropeptides capa receptor 0.0189 0.0302 0.03
Trypanosoma cruzi prefoldin subunit, putative 0.0066 0.0067 0.0078
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.107 0.1984 0.4728
Toxoplasma gondii proteasome subunit beta type, putative 0.0159 0.0245 0.0718
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0051 0.0062
Echinococcus granulosus biogenic amine 5HT receptor 0.0189 0.0302 0.03
Schistosoma mansoni neuropeptide receptor 0.0189 0.0302 0.0363
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Toxoplasma gondii EF hand domain-containing protein 0.0034 0.0006 0.0012
Schistosoma mansoni survival motor neuron protein 0.0097 0.0127 0.0152
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Plasmodium falciparum centrin-1 0.0195 0.0313 0.092
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4366 0.8281 1
Trypanosoma brucei Component of motile flagella 41 0.0195 0.0313 0.0742
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0022 0.0061
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0431 0.0764 0.2256
Echinococcus multilocularis transmembrane protease serine 3 0.0123 0.0176 0.0175
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0114 0.0158 0.0157
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0611 0.1109 0.1336
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1797 0.3374 0.4075
Schistosoma mansoni opsin-like receptor 0.0189 0.0302 0.0363
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0125 0.0179 0.0178
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.0169 0.0168
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.005 0.0037 0.0106
Brugia malayi Cathepsin L-like precursor 0.1797 0.3374 0.4075
Toxoplasma gondii calcium binding egf domain-containing protein 0.0072 0.0079 0.0227
Brugia malayi calpain 5 0.0476 0.0851 0.1027
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Giardia lamblia Programmed cell death protein-like protein 0.0034 0.0006 0.001
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0123 0.0176 0.0175
Trypanosoma brucei I/6 autoantigen 0.0195 0.0313 0.0742
Toxoplasma gondii histone deacetylase SIR2 0.0033 0.0003 0.0002
Trypanosoma cruzi cysteine proteinase, putative 0.0985 0.1822 0.2198
Schistosoma mansoni neuronal calcium sensor 0.0195 0.0313 0.0377
Echinococcus granulosus peptide allatostatin:somatostatin 0.0189 0.0302 0.03
Onchocerca volvulus 0.0123 0.0176 0.0519
Echinococcus granulosus calmodulin 0.0195 0.0313 0.0312
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0554 0.0999 0.1206
Brugia malayi Inositol-1 0.0036 0.0009 0.0011
Echinococcus multilocularis g-protein coupled receptor 0.0189 0.0302 0.03
Echinococcus multilocularis neuropeptide receptor A26 0.0189 0.0302 0.03
Plasmodium falciparum thioredoxin reductase 0.0104 0.014 0.0404
Trypanosoma brucei oligopeptidase b 0.0303 0.0519 0.1231
Schistosoma mansoni neuropeptide F-like receptor 0.0189 0.0302 0.0363
Brugia malayi beta-lactamase 0.0039 0.0016 0.0019
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.008 0.0093 0.0111
Loa Loa (eye worm) cathepsin B 0.1648 0.3089 0.373
Trypanosoma cruzi cysteine proteinase, putative 0.0985 0.1822 0.2198
Onchocerca volvulus Matrilysin homolog 0.0083 0.0099 0.0292
Trypanosoma brucei hypothetical protein 0.0761 0.1395 0.3323
Echinococcus multilocularis Calcium binding protein 0.0034 0.0006 0.0005
Onchocerca volvulus 0.02 0.0322 0.0952
Loa Loa (eye worm) hypothetical protein 0.0195 0.0313 0.0378
Brugia malayi hypothetical protein 0.0052 0.004 0.0048
Entamoeba histolytica dipeptidyl-peptidase, putative 0.008 0.0093 0.0266
Leishmania major cathepsin L-like protease 0.1797 0.3374 0.8045
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Onchocerca volvulus 0.0109 0.0149 0.0441
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0485 0.1151
Giardia lamblia Cathepsin B precursor 0.1648 0.3089 1
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0077 0.0225
Plasmodium falciparum serine repeat antigen 8 0.0431 0.0764 0.2256
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0093 0.0109
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.008 0.0093 0.0274
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0016 0.0019
Onchocerca volvulus 0.0045 0.0027 0.0079
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.107 0.1984 0.2394
Brugia malayi RE15519p 0.0189 0.0302 0.0364
Schistosoma mansoni chromatin regulatory protein sir2 0.0033 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0038 0.0012 0.0027
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0431 0.0764 0.2261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Echinococcus granulosus cathepsin l1 0.1797 0.3374 0.3374
Entamoeba histolytica prolyl oligopeptidase family protein 0.008 0.0093 0.0266
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0037 0.0045
Echinococcus multilocularis calbindin 32 0.02 0.0322 0.0321
Echinococcus granulosus thioredoxin glutathione reductase 0.0104 0.014 0.0138
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0701 0.128 0.1544
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0128 0.0184 0.0537
Echinococcus multilocularis cathepsin L cysteine protease 0.1797 0.3374 0.3374
Echinococcus multilocularis musashi 0.0058 0.0051 0.005
Brugia malayi Cathepsin L-like precursor 0.1243 0.2316 0.2797
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0189 0.0302 0.03
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0037 0.0045
Toxoplasma gondii cathepsin CPC2 0.0431 0.0764 0.2258
Brugia malayi Protein kinase domain containing protein 0.0089 0.011 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0034 0.0006 0.0016
Schistosoma mansoni calpain-7 (C02 family) 0.1248 0.2325 0.2806
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0051 0.0062
Echinococcus multilocularis laminin 0.0072 0.0079 0.0078
Trypanosoma brucei unspecified product 0.0225 0.037 0.0877
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0023 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0037 0.0045
Trypanosoma brucei cytochrome P450, putative 0.0068 0.0071 0.0164
Onchocerca volvulus Peroxidasin homolog 0.0109 0.0149 0.0441
Echinococcus multilocularis neuronal calcium sensor 0.0195 0.0313 0.0312
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0012 0.0011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.001 0.0017
Brugia malayi Trypsin family protein 0.0123 0.0176 0.0212
Echinococcus granulosus neuropeptide Y receptor 0.0189 0.0302 0.03
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0195 0.0313 0.0926
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0065 0.0077
Brugia malayi Papain family cysteine protease containing protein 0.0431 0.0764 0.0922
Toxoplasma gondii PAN/Apple domain-containing protein 0.0045 0.0027 0.0073
Echinococcus granulosus 7tm_1 domain containing protein 0.0189 0.0302 0.03
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.008 0.0093 0.0216
Trypanosoma cruzi centrin-3 0.023 0.0379 0.0455
Entamoeba histolytica cysteine protease, putative 0.0431 0.0764 0.2256
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0042 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Giardia lamblia Transglutaminase/protease, putative 0.007 0.0075 0.0232
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0037 0.0036
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0012 0.0015
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Toxoplasma gondii prolyl endopeptidase 0.0761 0.1394 0.4127
Echinococcus multilocularis Mastin 0.0123 0.0176 0.0175
Echinococcus granulosus expressed protein 0.0731 0.1336 0.1335
Trypanosoma brucei calpain, putative 0.0476 0.0851 0.2024
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0476 0.0851 0.2519
Leishmania major protein kinase, putative 0.0195 0.0313 0.0742
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Leishmania major hypothetical protein, conserved 0.0089 0.011 0.0257
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0303 0.0519 0.4167
Echinococcus granulosus tar DNA binding protein 0.0065 0.0065 0.0064
Onchocerca volvulus 0.0052 0.004 0.0117
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0011
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Schistosoma mansoni hypothetical protein 0.004 0.0017 0.0019
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0159 0.0245 0.0782
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0431 0.0764 0.2465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Onchocerca volvulus 0.0039 0.0016 0.0045
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0003 0.0003
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0189 0.0302 0.0363
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0189 0.0302 0.0363
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0315 0.0313
Trichomonas vaginalis kakapo, putative 0.0034 0.0006 0.0016
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0431 0.0764 0.2465
Brugia malayi cathepsin B-like cysteine proteinase 0.4366 0.8281 1
Echinococcus granulosus geminin 0.0858 0.1581 0.158
Schistosoma mansoni neuropeptide receptor 0.0189 0.0302 0.0363
Schistosoma mansoni cathepsin F (C01 family) 0.1797 0.3374 0.4074
Schistosoma mansoni chromatin regulatory protein sir2 0.0033 0.0003 0.0003
Schistosoma mansoni myosin regulatory light chain 0.0034 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0189 0.0302 0.0363
Entamoeba histolytica cysteine proteinase, putative 0.0985 0.1822 0.5396
Plasmodium vivax thioredoxin reductase, putative 0.0104 0.014 0.0404
Brugia malayi Dopamine receptor protein 2 0.0189 0.0302 0.0364
Loa Loa (eye worm) transcriptional regulator 0.0033 0.0003 0.0004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0682 0.1243 0.1499
Brugia malayi Matrixin family protein 0.0083 0.0099 0.0119
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0012 0.0011
Plasmodium falciparum glutathione reductase 0.0104 0.014 0.0404
Plasmodium falciparum cysteine proteinase falcipain 3 0.1797 0.3374 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0012 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0001 0.0001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0189 0.0302 0.0364
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0179 0.0215
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.004 0.0018 0.002
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.008 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Loa Loa (eye worm) RNA binding protein 0.0065 0.0065 0.0078
Toxoplasma gondii subtilisin SUB12 0.0045 0.0027 0.0073
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0123 0.0176 0.0211
Echinococcus granulosus cpg binding protein 0.0093 0.0118 0.0117
Trichomonas vaginalis centrin, putative 0.0195 0.0313 0.0926
Brugia malayi prolyl oligopeptidase family protein 0.008 0.0093 0.0112
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0016 0.0109
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0195 0.0313 0.092
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0127 0.0153
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Loa Loa (eye worm) cysteine protease 0.1797 0.3374 0.4075
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0062 0.0058 0.007
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0037 0.0044
Trypanosoma brucei calmodulin, putative 0.0195 0.0313 0.0742
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.297 0.5615 0.678
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0017 0.0049
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0009 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0985 0.1822 0.4342
Schistosoma mansoni chromobox protein 0.0071 0.0077 0.0091
Giardia lamblia Encystation-specific protease 0.0431 0.0764 0.2465
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0303 0.0519 1
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0761 0.1394 0.332
Schistosoma mansoni hypothetical protein 0.0056 0.0048 0.0057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.0764 0.0921
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.0764 0.0921
Echinococcus granulosus chromobox protein 1 0.0071 0.0077 0.0076
Echinococcus multilocularis programmed cell death protein 0.023 0.0379 0.0378
Echinococcus multilocularis cpg binding protein 0.0093 0.0118 0.0117
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0037 0.0036
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4366 0.8281 1
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0301 0.0516 0.0515
Plasmodium falciparum metacaspase 1 0.0043 0.0023 0.0057
Loa Loa (eye worm) hypothetical protein 0.0057 0.0049 0.006
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0122 0.0175 0.0173
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0123 0.0176 0.0212
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0003 0.0003
Trypanosoma brucei prolyl endopeptidase 0.0761 0.1394 0.332
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0015 0.0035
Schistosoma mansoni hypothetical protein 0.0821 0.151 0.1822
Trichomonas vaginalis calpain, putative 0.0476 0.0851 0.2519
Toxoplasma gondii hypothetical protein 0.0476 0.0851 0.2516
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0431 0.0764 0.2261
Brugia malayi Papain family cysteine protease containing protein 0.0985 0.1822 0.22
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0016 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0033
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0238 0.0394 0.7595
Trypanosoma cruzi prolyl endopeptidase 0.0761 0.1394 0.1681
Leishmania major kinesin, putative 0.0771 0.1414 0.3369
Brugia malayi cathepsin L-like cysteine proteinase 0.0431 0.0764 0.0922
Brugia malayi Cytochrome P450 family protein 0.0032 0.0003 0.0003
Echinococcus multilocularis muscleblind protein 1 0.0155 0.0236 0.0235
Echinococcus granulosus cathepsin L 0.0985 0.1822 0.1821
Echinococcus multilocularis neuropeptides capa receptor 0.0189 0.0302 0.03
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0015
Onchocerca volvulus Arrow homolog 0.0066 0.0068 0.0199
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0141 0.021 0.0209
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0037 0.0036
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0476 0.0851 0.2024
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0037 0.0045
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0197 0.0317 0.0383
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0012 0.0011
Echinococcus granulosus neuronal calcium sensor 0.0195 0.0313 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0431 0.0764 0.2261
Mycobacterium tuberculosis Long conserved protein 0.007 0.0075 0.0586
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0159 0.0245 0.0295
Loa Loa (eye worm) melatonin receptor type 1A 0.0189 0.0302 0.0364
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0065 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0985 0.1822 0.5399
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0033 0.0003 0.0002
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0169 0.0202
Giardia lamblia Cathepsin B precursor 0.0431 0.0764 0.2465
Trypanosoma brucei kinesin, putative 0.0771 0.1414 0.3369
Echinococcus multilocularis tachykinin peptides receptor 99D 0.5265 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Echinococcus multilocularis chromatin regulatory protein sir2 0.0128 0.0184 0.0183
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0023 0.0064
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0264 0.0445 0.3573
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.001 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.008 0.0093 0.0216
Schistosoma mansoni neuronal calcium sensor 0.0195 0.0313 0.0377
Brugia malayi Cathepsin L-like precursor 0.1243 0.2316 0.2797
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1533 0.2869 0.3463
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.0169 0.0202
Trichomonas vaginalis esterase, putative 0.0039 0.0016 0.0043
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0034 0.004
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0027 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Trypanosoma cruzi centrin, putative 0.023 0.0379 0.0455
Schistosoma mansoni neuropeptide receptor 0.0189 0.0302 0.0363
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Plasmodium falciparum serine repeat antigen 5 0.0431 0.0764 0.2256
Trypanosoma brucei metacaspase MCA3 0.0043 0.0023 0.0048
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0476 0.0851 0.2519
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0043 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis thyroid hormone receptor alpha 0.0188 0.03 0.0299
Toxoplasma gondii calcium-dependent protein kinase 0.02 0.0322 0.0947
Giardia lamblia Cathepsin L precursor 0.0431 0.0764 0.2465
Schistosoma mansoni opsin-like receptor 0.0189 0.0302 0.0363
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0006 0.0011
Trichomonas vaginalis caltractin, putative 0.0034 0.0006 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis somatostatin receptor 0.0189 0.0302 0.03
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus granulosus cathepsin L 0.0431 0.0764 0.0763
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.001 0.0008
Giardia lamblia Cysteine protease 0.0431 0.0764 0.2465
Onchocerca volvulus 0.0189 0.0302 0.0893
Loa Loa (eye worm) myosin regulatory light chain 1 0.0034 0.0006 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Brugia malayi cathepsin L precursor 0.0431 0.0764 0.0922
Giardia lamblia Hypothetical protein 0.007 0.0075 0.0232
Onchocerca volvulus 0.0109 0.0149 0.0441
Echinococcus multilocularis cysteine protease 0.1797 0.3374 0.3374
Echinococcus granulosus prolyl endopeptidase 0.0761 0.1394 0.1393
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0042 0.0095
Trichomonas vaginalis myosin light chain 1, putative 0.0195 0.0313 0.0926
Entamoeba histolytica calpain large subunit domain III containing protein 0.0771 0.1414 0.4186
Echinococcus granulosus EF HAND 1 calcium binding site 0.0195 0.0313 0.0312
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0431 0.0764 0.2256
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0122 0.0175 0.0208
Echinococcus granulosus Mastin 0.0123 0.0176 0.0175
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0164 0.0255 0.0254
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0701 0.128 0.1544
Brugia malayi follicle stimulating hormone receptor 0.0189 0.0302 0.0364
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1648 0.3089 0.3728
Giardia lamblia Cathepsin B precursor 0.0431 0.0764 0.2465
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0033 0.0003 0.0007
Brugia malayi Matrixin family protein 0.0083 0.0099 0.0119
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) matrix metalloproteinase 0.0083 0.0099 0.0119
Brugia malayi neuropeptide F receptor 0.0189 0.0302 0.0364
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0141 0.021 0.062
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0364 0.0637 0.0766
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Schistosoma mansoni amine GPCR 0.0189 0.0302 0.0363
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0189 0.0302 0.03
Mycobacterium ulcerans hypothetical protein 0.0039 0.0016 0.0256
Echinococcus granulosus lamin dm0 0.0058 0.0051 0.005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.0169 0.0168
Onchocerca volvulus 0.0051 0.0037 0.0109
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0431 0.0764 0.0922
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0303 0.0519 0.1231
Schistosoma mansoni chromobox protein 0.0071 0.0077 0.0091
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0012 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.037 0.0444
Brugia malayi Cell death protein 3 precursor 0.0083 0.0099 0.0119
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0012 0.0013
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0034 0.0038
Echinococcus granulosus cysteine protease 0.0985 0.1822 0.1821
Loa Loa (eye worm) hypothetical protein 0.0101 0.0133 0.0161
Echinococcus multilocularis g protein coupled receptor 0.0189 0.0302 0.03
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0225 0.037 0.0877
Brugia malayi cathepsin F-like cysteine proteinase 0.0431 0.0764 0.0922
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0015
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Entamoeba histolytica protein kinase, putative 0.0771 0.1414 0.4186
Entamoeba histolytica cysteine proteinase, putative 0.1797 0.3374 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1023 0.1894 0.4513
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0164 0.0255 0.0308
Schistosoma mansoni coup transcription factor 0.0051 0.0037 0.0044
Onchocerca volvulus 0.0123 0.0176 0.0519
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0027 0.0073
Echinococcus multilocularis Myosin regulatory light chain 0.0034 0.0006 0.0005
Onchocerca volvulus 0.0034 0.0006 0.0018
Schistosoma mansoni peroxidasin 0.0109 0.0149 0.0179
Loa Loa (eye worm) hypothetical protein 0.0108 0.0148 0.0178
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Onchocerca volvulus 0.0123 0.0176 0.0519
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0094 0.0093
Entamoeba histolytica calcium-binding protein, putative 0.0195 0.0313 0.092
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.001 0.0017
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0189 0.0302 0.0363
Echinococcus granulosus cathepsin b 0.4366 0.8281 0.8281
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0009
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0033 0.0003 0.0007
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0159 0.0245 0.0292
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Trypanosoma brucei Calpain-like protein 1.2 0.0858 0.1579 0.3761
Schistosoma mansoni intermediate filament proteins 0.0058 0.0051 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0838 0.1542 0.3673
Leishmania major cytochrome p450-like protein 0.0068 0.0071 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Schistosoma mansoni hypothetical protein 0.0123 0.0176 0.0211
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0012 0.0013
Leishmania major calmodulin-like protein 0.0195 0.0313 0.0742
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0303 0.0519 0.0623
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi Calcium binding EGF domain containing protein 0.0072 0.0079 0.0096
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0071 0.0086
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Onchocerca volvulus 0.0045 0.0027 0.0079
Plasmodium vivax proteasome subunit beta type-5, putative 0.0159 0.0245 0.0716
Giardia lamblia Hypothetical protein 0.0128 0.0184 0.0586
Echinococcus granulosus calpain A 0.1248 0.2325 0.2324
Echinococcus granulosus chromobox protein 1 0.0071 0.0077 0.0076
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0431 0.0764 0.2256
Onchocerca volvulus 0.0189 0.0302 0.0893
Mycobacterium leprae Conserved hypothetical protein 0.007 0.0075 0.1405
Onchocerca volvulus 0.0189 0.0302 0.0893
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0141 0.021 0.0671
Brugia malayi Probable myosin regulatory light chain 0.0039 0.0015 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0037 0.0045
Onchocerca volvulus 0.0045 0.0027 0.0079
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.002
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0027 0.0073
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0012 0.0013
Plasmodium vivax vivapain-2 0.1797 0.3374 1
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.001 0.0025
Plasmodium vivax unspecified product 0.0431 0.0764 0.2256
Onchocerca volvulus 0.0045 0.0027 0.0079
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0063 0.0062 0.0075
Brugia malayi proteasome subunit beta type 1 0.0122 0.0175 0.0211
Brugia malayi aspartic protease BmAsp-2, identical 0.0052 0.004 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0431 0.0764 0.2261
Echinococcus granulosus neuropeptide Y receptor 0.0189 0.0302 0.03
Echinococcus multilocularis fmrfamide receptor 0.0189 0.0302 0.03
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0066 0.0068 0.0082
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.042 0.3374
Echinococcus multilocularis neuropeptide Y receptor 0.0189 0.0302 0.03
Leishmania major centrin, putative,caltractin, putative 0.0195 0.0313 0.0742
Trypanosoma brucei SIR2-like protein 4, putative 0.0033 0.0003 0.0002
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0195 0.0313 0.0375
Trypanosoma cruzi 20S proteasome subunit 0.005 0.0037 0.0041
Echinococcus multilocularis dna polymerase eta 0.0049 0.0034 0.0033
Brugia malayi glutathione reductase 0.0104 0.014 0.0169
Loa Loa (eye worm) hypothetical protein 0.0141 0.021 0.0254
Loa Loa (eye worm) hypothetical protein 0.008 0.0093 0.0112
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0016 0.0256
Schistosoma mansoni cathepsin D (A01 family) 0.0451 0.0803 0.0969
Plasmodium falciparum serine repeat antigen 2 0.0431 0.0764 0.2256
Plasmodium falciparum plasmepsin II 0.0164 0.0255 0.0746
Onchocerca volvulus 0.0045 0.0027 0.0079
Trichomonas vaginalis calcineurin B subunit, putative 0.02 0.0322 0.0951
Echinococcus granulosus sex peptide receptor 0.0189 0.0302 0.03
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.3165 0.5988 0.5987
Schistosoma mansoni myosin regulatory light chain 0.0034 0.0006 0.0006
Onchocerca volvulus 0.0431 0.0764 0.2263
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0149 0.018
Schistosoma mansoni hypothetical protein 0.0858 0.1581 0.1907
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1453 0.2717 0.3279
Trypanosoma brucei metacaspase 5, putative 0.0043 0.0023 0.0048
Loa Loa (eye worm) inositol-1 0.0036 0.0009 0.0011
Mycobacterium tuberculosis Conserved protein 0.0039 0.0016 0.0109
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0476 0.0851 0.2519
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0012 0.0011
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0123 0.0176 0.0211
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0761 0.1394 0.1682
Brugia malayi Thioredoxin reductase 0.0104 0.014 0.0169
Echinococcus granulosus somatostatin receptor 0.0189 0.0302 0.03
Echinococcus multilocularis prefoldin subunit 6 0.0066 0.0067 0.0066
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0123 0.0176 0.0175
Entamoeba histolytica grainin 2 0.0034 0.0006 0.0009
Giardia lamblia Cathepsin L-like protease 0.0431 0.0764 0.2465
Echinococcus granulosus neurocalcin 0.0195 0.0313 0.0312
Leishmania major sir2-family protein-like protein 0.0033 0.0003 0.0002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0037 0.0044
Echinococcus multilocularis peroxidasin 0.0109 0.0149 0.0148
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0431 0.0764 0.0922
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1797 0.3374 1
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0012 0.0011
Echinococcus granulosus neuropeptide receptor A26 0.0189 0.0302 0.03
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.001 0.0009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1797 0.3374 0.4075
Trypanosoma cruzi kinesin, putative 0.0771 0.1414 0.1706
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.005 0.0037 0.0043
Loa Loa (eye worm) prolyl oligopeptidase 0.008 0.0093 0.0112
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Plasmodium vivax unspecified product 0.0554 0.0999 0.2954
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0009 0.0018
Onchocerca volvulus 0.0189 0.0302 0.0893
Schistosoma mansoni DNA polymerase eta 0.0049 0.0034 0.004
Onchocerca volvulus 0.0045 0.0027 0.0079
Plasmodium vivax serine-repeat antigen (SERA) 0.0431 0.0764 0.2256
Leishmania major small myristoylated protein-2 0.0707 0.1291 0.3074
Echinococcus granulosus transmembrane protease serine 3 0.0123 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.031 0.0532 0.0642
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1248 0.2325 0.2805
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0033 0.0003 0.0009
Plasmodium vivax plasmepsin V, putative 0.0052 0.004 0.0108
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0128 0.0184 0.0183
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0003 0.0003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Echinococcus granulosus survival motor neuron protein 1 0.0478 0.0854 0.0853
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0027 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0067 0.0196
Giardia lamblia Cathepsin B precursor 0.1648 0.3089 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0189 0.0302 0.0364
Trypanosoma cruzi cytochrome P450, putative 0.0068 0.0071 0.0083
Echinococcus multilocularis chromobox protein 1 0.0071 0.0077 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0141 0.021 0.062
Brugia malayi Trypsin-like protease protein 5 0.0123 0.0176 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0012 0.0013
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0164 0.0255 0.0254
Loa Loa (eye worm) hypothetical protein 0.0195 0.0313 0.0378
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0137 0.0203 0.0202
Mycobacterium ulcerans beta-lactamase 0.0039 0.0016 0.0256
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0094 0.0093
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0003 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.0189 0.0302 0.03
Trichomonas vaginalis centrin, putative 0.0195 0.0313 0.0926
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Toxoplasma gondii kringle domain-containing protein 0.0089 0.011 0.0319
Brugia malayi AKH receptor 0.0189 0.0302 0.0364
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0858 0.1579 0.1904
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0003 0.0003
Toxoplasma gondii EF hand domain-containing protein 0.0195 0.0313 0.0922
Brugia malayi nuclear hormone receptor 0.0051 0.0037 0.0045
Mycobacterium ulcerans hydrolase 0.0101 0.0133 0.2537
Giardia lamblia Calmodulin 0.0034 0.0006 0.001
Leishmania major proteasome beta 2 subunit, putative 0.005 0.0037 0.0081
Trichomonas vaginalis calcium binding protein, putative 0.0195 0.0313 0.0926
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0077 0.0225
Echinococcus granulosus calpain A 0.317 0.5996 0.5996
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0225 0.037 0.0444
Onchocerca volvulus 0.0045 0.0027 0.0079
Loa Loa (eye worm) hypothetical protein 0.0346 0.0602 0.0727
Loa Loa (eye worm) hypothetical protein 0.0431 0.0764 0.0922
Leishmania major metacaspase, putative 0.0043 0.0023 0.0048
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0125 0.0179 0.0524
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0037 0.0045
Mycobacterium ulcerans NAD-dependent deacetylase 0.0033 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1023 0.1894 0.4513
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0041
Brugia malayi sulfakinin receptor protein 0.0189 0.0302 0.0364
Brugia malayi Heterochromatin protein 1 0.0071 0.0077 0.0093
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.008 0.0093 0.0109
Echinococcus multilocularis muscleblind protein 0.0155 0.0236 0.0235
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0037 0.0036
Schistosoma mansoni hypothetical protein 0.0137 0.0203 0.0244
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0066 0.0068 0.0082
Loa Loa (eye worm) hypothetical protein 0.0431 0.0764 0.0922
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0065 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0985 0.1822 0.2198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0431 0.0764 0.2261
Echinococcus granulosus laminin 0.0072 0.0079 0.0078
Plasmodium vivax hypothetical protein, conserved 0.02 0.0322 0.0945
Loa Loa (eye worm) thioredoxin reductase 0.0104 0.014 0.0169
Plasmodium falciparum plasmepsin V 0.0052 0.004 0.0108
Onchocerca volvulus 0.1797 0.3374 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0315 0.0313
Loa Loa (eye worm) hypothetical protein 0.1243 0.2316 0.2797
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0123 0.0176 0.0211
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0823 0.1512 0.3602
Giardia lamblia Cysteine protease 0.0431 0.0764 0.2465
Onchocerca volvulus 0.1797 0.3374 1
Brugia malayi Eukaryotic aspartyl protease family protein 0.0052 0.004 0.0048
Mycobacterium tuberculosis Conserved protein 0.0039 0.0016 0.0109
Echinococcus granulosus EF hand domain containing family member A2 0.0195 0.0313 0.0312
Brugia malayi Papain family cysteine protease containing protein 0.1797 0.3374 0.4075
Onchocerca volvulus 0.0189 0.0302 0.0893
Brugia malayi calpain D 0.0476 0.0851 0.1027
Trichomonas vaginalis set domain proteins, putative 0.0977 0.1808 0.5356
Onchocerca volvulus 0.0189 0.0302 0.0893
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0164 0.0255 0.0308
Leishmania major hypothetical protein, conserved 0.0225 0.037 0.0877
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0122 0.0175 0.0508
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.008 0.0093 0.0092
Trypanosoma brucei proteasome beta 6 subunit 0.0122 0.0175 0.041
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0037 0.0036
Leishmania major trypanothione reductase 0.0104 0.014 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0476 0.0851 0.2519
Echinococcus granulosus cathepsin L cysteine protease 0.0985 0.1822 0.1821
Echinococcus granulosus cathepsin l cysteine peptidase 0.1797 0.3374 0.3374
Onchocerca volvulus 0.1797 0.3374 1
Echinococcus multilocularis fmrfamide receptor 0.0189 0.0302 0.03
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0039 0.0015 0.0014
Echinococcus multilocularis sodium channel protein 0.0039 0.0015 0.0014
Entamoeba histolytica hypothetical protein 0.0038 0.0012 0.0027
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.008 0.0093 0.0111
Schistosoma mansoni hypothetical protein 0.0189 0.0302 0.0363
Loa Loa (eye worm) fibroinase 0.1797 0.3374 0.4075
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0682 0.1243 0.1499
Onchocerca volvulus 0.1797 0.3374 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0858 0.1579 0.1904
Trypanosoma brucei calmodulin, putative 0.02 0.0322 0.0762
Brugia malayi Matrixin family protein 0.0083 0.0099 0.0119
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.001 0.0137
Echinococcus multilocularis calpain family protein 1, d 0.2199 0.4141 0.4141
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0027 0.0073
Brugia malayi PXA domain containing protein 0.0038 0.0012 0.0015
Trypanosoma cruzi caltractin, putative 0.0195 0.0313 0.0375
Echinococcus granulosus tm gpcr rhodopsin 0.0189 0.0302 0.03
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.008 0.0093 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0023 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0037 0.0045
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0191 0.0306 0.0368
Mycobacterium leprae Conserved hypothetical protein 0.007 0.0075 0.1405
Echinococcus multilocularis calmodulin 0.0195 0.0313 0.0312
Onchocerca volvulus Prolyl endopeptidase homolog 0.0761 0.1394 0.413
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1797 0.3374 0.3374
Plasmodium vivax aspartyl protease, putative 0.0052 0.004 0.0108
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0216 0.0261
Schistosoma mansoni growth hormone secretagogue receptor 0.0189 0.0302 0.0363
Plasmodium vivax metacaspase 1, putative 0.0043 0.0023 0.0057
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1248 0.2325 0.2805
Toxoplasma gondii microneme protein MIC17B 0.0045 0.0027 0.0073
Schistosoma mansoni chromatin regulatory protein sir2 0.0128 0.0184 0.0221
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0009 0.0008
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0037 0.0045
Giardia lamblia Cathepsin L precursor 0.0431 0.0764 0.2465
Brugia malayi Pre-SET motif family protein 0.0859 0.1582 0.191
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0017 0.0016
Schistosoma mansoni amine GPCR 0.0189 0.0302 0.0363
Trichomonas vaginalis centrin, putative 0.0034 0.0006 0.0016
Onchocerca volvulus 0.0978 0.1809 0.5359
Trypanosoma cruzi cytochrome P450, putative 0.0068 0.0071 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0431 0.0764 0.2261
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0431 0.0764 0.2256
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Brugia malayi cathepsin Z-like cysteine proteinase 0.0431 0.0764 0.0922
Brugia malayi G-protein coupled receptor 0.0189 0.0302 0.0364
Trypanosoma cruzi small myristoylated protein 1-1 0.0388 0.0682 0.082
Loa Loa (eye worm) hypothetical protein 0.0431 0.0764 0.0922
Schistosoma mansoni cathepsin D (A01 family) 0.0451 0.0803 0.0969
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0016 0.0019
Onchocerca volvulus 0.0189 0.0302 0.0893
Trypanosoma brucei Calpain-like protein CALP1.3 0.0701 0.128 0.3049
Schistosoma mansoni peroxidasin 0.0109 0.0149 0.0179
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0225 0.037 0.0877
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1797 0.3374 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0137 0.0203 0.0202
Leishmania major oligopeptidase b 0.0303 0.0519 0.1231
Onchocerca volvulus 0.0123 0.0176 0.0519
Toxoplasma gondii calcium binding egf domain-containing protein 0.0072 0.0079 0.0227
Giardia lamblia Alanyl dipeptidyl peptidase 0.008 0.0093 0.0291
Entamoeba histolytica cysteine protease, putative 0.1797 0.3374 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Leishmania major proteasome beta 5 subunit, putative 0.0159 0.0245 0.0578
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.008 0.0093 0.0109
Onchocerca volvulus 0.0058 0.0051 0.0151
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0149 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0019
Onchocerca volvulus 0.0039 0.0016 0.0045
Plasmodium vivax proteasome subunit beta type-1, putative 0.0122 0.0175 0.0508
Onchocerca volvulus Matrix metalloproteinase homolog 0.0184 0.0292 0.0863
Echinococcus granulosus caspase 8 0.0043 0.0023 0.0021
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.0075 0.0586
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0027 0.0073
Giardia lamblia Cathepsin L precursor 0.0431 0.0764 0.2465
Echinococcus multilocularis cysteine protease 0.1797 0.3374 0.3374
Schistosoma mansoni biogenic amine receptor 0.0189 0.0302 0.0363
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Trypanosoma cruzi unspecified product 0.0388 0.0682 0.082
Trypanosoma brucei protein I/6 0.0195 0.0313 0.0742
Schistosoma mansoni chromatin regulatory protein sir2 0.0128 0.0184 0.0221
Entamoeba histolytica hypothetical protein 0.0431 0.0764 0.2256
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0023 0.0024
Brugia malayi transcriptional regulator, Sir2 family protein 0.0033 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus multilocularis EF hand domain containing family member A2 0.02 0.0322 0.0321
Plasmodium vivax prefoldin subunit 6, putative 0.0066 0.0067 0.019
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0701 0.128 0.1544
Giardia lamblia Proteasome subunit beta type 2 0.005 0.0037 0.0108
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0065 0.0078
Trypanosoma brucei antigen, putative 0.1248 0.2325 0.5541
Echinococcus granulosus programmed cell death protein 0.023 0.0379 0.0378
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0037 0.0036
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0012 0.0011
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0033 0.0003 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.0043 0.0023 0.0024
Echinococcus granulosus caspase 3 0.0071 0.0076 0.0074
Echinococcus multilocularis caspase 8 0.0043 0.0023 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2226 0.4194 1
Onchocerca volvulus 0.0083 0.0099 0.0292
Onchocerca volvulus 0.0189 0.0302 0.0893
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0476 0.0851 0.2516
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.037 0.0444
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0033 0.0003 0.0002
Loa Loa (eye worm) neuropeptide F receptor 0.0189 0.0302 0.0364
Schistosoma mansoni hypothetical protein 0.0189 0.0302 0.0363
Entamoeba histolytica hypothetical protein, conserved 0.02 0.0322 0.0945
Leishmania major calpain family cysteine protease-like protein 0.0701 0.128 0.3049
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0431 0.0764 0.0922
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0012 0.0013
Trypanosoma cruzi cruzipain precursor, putative 0.0554 0.0999 0.1204
Toxoplasma gondii hypothetical protein 0.0045 0.0027 0.0073
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0225 0.037 0.0877
Trypanosoma cruzi kinesin, putative 0.0771 0.1414 0.1706
Leishmania major cathepsin L-like protease 0.2226 0.4194 1
Schistosoma mansoni dopamine-beta-monooxygenase 0.0125 0.018 0.0215
Echinococcus granulosus 7TM GPCR rhodopsin 0.0189 0.0302 0.03
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Entamoeba histolytica prolyl oligopeptidase family protein 0.008 0.0093 0.0266
Echinococcus multilocularis expressed protein 0.0731 0.1336 0.1335
Trypanosoma cruzi cysteine peptidase, putative 0.1797 0.3374 0.4073
Plasmodium falciparum plasmepsin X 0.0052 0.004 0.0108
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.001 0.0025
Toxoplasma gondii centrin 0.0195 0.0313 0.0922
Trypanosoma brucei calpain, putative 0.0761 0.1395 0.3323
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0195 0.0313 0.092
Brugia malayi Cathepsin L-like precursor 0.1797 0.3374 0.4075
Plasmodium vivax centrin-1, putative 0.0195 0.0313 0.092
Loa Loa (eye worm) hypothetical protein 0.0043 0.0023 0.0027
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0052 0.004 0.0111
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0083 0.0099 0.0118
Entamoeba histolytica cysteine proteinase 2 0.0985 0.1822 0.5396
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0016 0.0109
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0195 0.0313 0.0312
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0701 0.128 0.1544
Brugia malayi transcriptional regulator, Sir2 family protein 0.0128 0.0184 0.0222
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0128 0.0184 0.0434
Leishmania major hypothetical protein, conserved 0.0039 0.0016 0.0031
Schistosoma mansoni biogenic amine receptor 0.0189 0.0302 0.0363
Schistosoma mansoni caspase-7 (C14 family) 0.0114 0.0158 0.0189
Schistosoma mansoni lamin 0.0058 0.0051 0.0061
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0012 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0037 0.0045
Leishmania major calcineurin B subunit, putative 0.0195 0.0313 0.0742
Brugia malayi PXA domain containing protein 0.0038 0.0012 0.0015
Brugia malayi GnHR receptor homolog 0.0189 0.0302 0.0364
Trypanosoma cruzi calmodulin, putative 0.0195 0.0313 0.0375
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0132 0.0159
Echinococcus granulosus caspase 0.0114 0.0158 0.0157
Plasmodium falciparum serine repeat antigen 9 0.0431 0.0764 0.2256
Brugia malayi RNA binding protein 0.0065 0.0065 0.0078
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0195 0.0313 0.0742
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0195 0.0313 0.0742
Schistosoma mansoni hypothetical protein 0.0858 0.1581 0.1907
Brugia malayi putative neuropeptide receptor 0.0189 0.0302 0.0364
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0037 0.0036
Schistosoma mansoni inositol monophosphatase 0.0036 0.0009 0.001
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0012 0.0015
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Brugia malayi Matrixin family protein 0.02 0.0323 0.0391
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0016 0.0018
Schistosoma mansoni hypothetical protein 0.0195 0.0313 0.0377
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0101 0.0133 0.0161
Trypanosoma brucei calpain-like protein, putative 0.1248 0.2325 0.5541
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0823 0.1512 0.1824
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Loa Loa (eye worm) matrixin family protein 0.02 0.0323 0.0391
Leishmania major hypothetical protein, conserved 0.0053 0.0042 0.0095
Schistosoma mansoni calcium binding atopy-related autoantigen 0.02 0.0322 0.0387
Echinococcus multilocularis caspase 2 0.0083 0.0099 0.0098
Toxoplasma gondii calmodulin, putative 0.0034 0.0006 0.0012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0985 0.1822 0.2199
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0235 0.039 0.0389
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.0169 0.1345
Loa Loa (eye worm) hypothetical protein 0.0476 0.0851 0.1027
Onchocerca volvulus 0.1797 0.3374 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0554 0.0999 0.1206
Echinococcus granulosus tm gpcr rhodopsin 0.0189 0.0302 0.03
Trichomonas vaginalis calcium binding protein, putative 0.0034 0.0006 0.0016
Echinococcus granulosus neuropeptide receptor 0.0189 0.0302 0.03
Echinococcus multilocularis neuropeptide receptor 0.0189 0.0302 0.03
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0012 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0195 0.0313 0.0742
Trichomonas vaginalis calcium binding proteins, putative 0.0195 0.0313 0.0926
Toxoplasma gondii aspartyl protease ASP3 0.0052 0.004 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0137 0.0201 0.0596
Entamoeba histolytica cysteine proteinase, putative 0.0985 0.1822 0.5396
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0485 0.1151
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0003 0.0007
Trypanosoma cruzi metacaspase, putative 0.0043 0.0023 0.0024
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0189 0.0302 0.0363
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0235 0.039 0.0471
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0195 0.0313 0.0375
Loa Loa (eye worm) hypothetical protein 0.0554 0.0999 0.1206
Echinococcus multilocularis calcium uptake protein 1 0.02 0.0322 0.0321
Loa Loa (eye worm) hypothetical protein 0.0066 0.0068 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0125 0.0179 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0189 0.0302 0.03
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0037 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) TK/ROR protein kinase 0.0089 0.011 0.0133
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Trypanosoma cruzi trypanothione reductase, putative 0.0104 0.014 0.0166
Brugia malayi Melatonin receptor type 1A 0.0189 0.0302 0.0364
Brugia malayi cathepsin L-like precursor 0.1243 0.2316 0.2797
Onchocerca volvulus 0.1797 0.3374 1
Brugia malayi EF hand family protein 0.0195 0.0313 0.0378
Loa Loa (eye worm) hypothetical protein 0.0431 0.0764 0.0922
Onchocerca volvulus Cathepsin L homolog 0.1797 0.3374 1
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0016 0.0109
Echinococcus multilocularis fibrillin 1 0.0072 0.0079 0.0078
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.001 0.0008
Echinococcus granulosus fmrfamide receptor 0.0189 0.0302 0.03
Plasmodium vivax glutathione reductase, putative 0.0104 0.014 0.0404
Giardia lamblia Proteasome subunit beta type 1 0.0122 0.0175 0.0555
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.001 0.0012
Loa Loa (eye worm) cytochrome P450 0.0032 0.0003 0.0003
Echinococcus granulosus calcyphosin protein 0.0034 0.0006 0.0005
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0303 0.0519 0.1231
Loa Loa (eye worm) hypothetical protein 0.0034 0.0006 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0023 0.0064
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0958 0.1772 0.4221
Brugia malayi hypothetical protein 0.0038 0.0012 0.0015
Trichomonas vaginalis caltractin, putative 0.0034 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) sirtuin 4 0.0033 0.0003 0.0004
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0122 0.0175 0.041
Giardia lamblia Hypothetical protein 0.0431 0.0764 0.2465
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0431 0.0764 0.0921
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0189 0.0302 0.0364
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0077 0.0093
Trypanosoma brucei small myristoylated protein 1-2 0.0388 0.0682 0.162
Brugia malayi programmed cell death protein 6 0.0195 0.0313 0.0378
Brugia malayi MH2 domain containing protein 0.0254 0.0426 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0065 0.0077
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0431 0.0764 0.2256
Brugia malayi putative neuropeptide receptor NPR1 0.0189 0.0302 0.0364
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0037 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Entamoeba histolytica cysteine protease, putative 0.0431 0.0764 0.2256
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0009 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0958 0.1772 0.4221
Schistosoma mansoni hypothetical protein 0.0066 0.0067 0.008
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0012 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.1797 0.3374 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) matrixin family protein 0.0184 0.0292 0.0352
Brugia malayi Kringle domain containing protein 0.0089 0.011 0.0133
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0132 0.0159
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0016 0.0109
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.02 0.0322 0.0386
Loa Loa (eye worm) hypothetical protein 0.0031 0 0.0001
Echinococcus granulosus neuropeptide s receptor 0.0189 0.0302 0.03
Schistosoma mansoni cathepsin s 0.0554 0.0999 0.1205
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Plasmodium falciparum cysteine proteinase falcipain 1 0.0985 0.1822 0.5396
Leishmania major cysteine peptidase A (CPA) 0.1797 0.3374 0.8045
Echinococcus multilocularis acylamino acid releasing enzyme 0.008 0.0093 0.0092
Brugia malayi hypothetical protein 0.0189 0.0302 0.0364
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1248 0.2325 0.5541
Brugia malayi ecdysteroid receptor 0.0051 0.0037 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.037 0.0444
Brugia malayi hypothetical protein 0.0133 0.0194 0.0235
Onchocerca volvulus 0.0195 0.0313 0.0927
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0189 0.0302 0.03
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Schistosoma mansoni hypothetical protein 0.0195 0.0313 0.0377
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.008 0.0093 0.0216
Onchocerca volvulus 0.0189 0.0302 0.0893
Schistosoma mansoni amine GPCR 0.0189 0.0302 0.0363
Loa Loa (eye worm) hypothetical protein 0.0123 0.0176 0.0212
Schistosoma mansoni hypothetical protein 0.0089 0.011 0.0131
Echinococcus multilocularis microtubule associated protein 2 0.1336 0.2494 0.2493
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0229 0.0378 0.0456
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0159 0.0245 0.0716
Leishmania major small myristoylated protein-3, putative 0.0329 0.0568 0.135
Trypanosoma brucei Calpain-like protein 1.1 0.107 0.1984 0.4728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Onchocerca volvulus Peroxidase homolog 0.0109 0.0149 0.0441
Loa Loa (eye worm) hypothetical protein 0.0072 0.0079 0.0096
Echinococcus multilocularis calpain A 0.317 0.5996 0.5996
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0169 0.3222
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Loa Loa (eye worm) beta-lactamase 0.0039 0.0016 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0016 0.0037
Loa Loa (eye worm) EF hand family protein 0.0195 0.0313 0.0378
Plasmodium falciparum serine repeat antigen 4 0.0431 0.0764 0.2256
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0128 0.0184 0.0219
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0554 0.0999 0.1206
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0042 0.0048
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0139 0.0206 0.0247
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0189 0.0302 0.0363
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Echinococcus multilocularis orexin receptor type 2 0.0189 0.0302 0.03
Loa Loa (eye worm) transcription factor SMAD2 0.0254 0.0426 0.0514
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Schistosoma mansoni myosin light chain 0.0034 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0004 0.0005
Trypanosoma cruzi small myristoylated protein 1-2 0.0388 0.0682 0.082
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0019
Trypanosoma cruzi I/6 autoantigen, putative 0.0195 0.0313 0.0375
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1797 0.3374 1
Echinococcus granulosus tissue type plasminogen activator 0.0089 0.011 0.0109
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0023 0.0064
Leishmania major i/6 autoantigen-like protein 0.0195 0.0313 0.0742
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0037 0.0044
Plasmodium falciparum peptidase, putative 0.008 0.0093 0.0266
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4366 0.8281 1
Mycobacterium ulcerans lipase LipD 0.0039 0.0016 0.0256
Loa Loa (eye worm) hypothetical protein 0.0109 0.0149 0.018
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.0169 0.0493
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0682 0.1243 0.2961
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Entamoeba histolytica hypothetical protein, conserved 0.008 0.0093 0.0266
Leishmania major hypothetical protein, conserved 0.0225 0.037 0.0877
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Trichomonas vaginalis calmodulin, putative 0.0195 0.0313 0.0926
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0485 0.1151
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1672 0.3135 0.3784
Loa Loa (eye worm) calpain family protein 1 0.2199 0.4141 0.5001
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0301 0.0516 0.0515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0072 0.0079 0.0096
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0431 0.0764 0.2256
Plasmodium vivax aspartyl protease, putative 0.0052 0.004 0.0108
Plasmodium falciparum glutathione reductase 0.0036 0.001 0.0019
Echinococcus granulosus neuropeptide receptor 0.0189 0.0302 0.03
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.001 0.0019
Schistosoma mansoni cathepsin F (C01 family) 0.1243 0.2316 0.2796
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0052 0.004 0.0048
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0189 0.0302 0.03
Entamoeba histolytica cysteine proteinase, putative 0.0985 0.1822 0.5396
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0701 0.128 0.3049
Brugia malayi Cytochrome P450 family protein 0.0068 0.0071 0.0086
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0128 0.0184 0.0537
Trypanosoma cruzi cruzipain precursor, putative 0.2226 0.4194 0.5063
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0003 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.0189 0.0302 0.03
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0235 0.039 0.047
Leishmania major DNA polymerase eta, putative 0.0034 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Echinococcus multilocularis centrin 2 0.0195 0.0313 0.0312
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0431 0.0764 0.2256
Plasmodium falciparum plasmepsin IV 0.0164 0.0255 0.0746
Trypanosoma cruzi cysteine peptidase, putative 0.2226 0.4194 0.5063
Loa Loa (eye worm) trypsin family protein 0.0123 0.0176 0.0212
Echinococcus multilocularis lamin dm0 0.0058 0.0051 0.005
Brugia malayi Dopamine receptor protein 1 0.0189 0.0302 0.0364
Brugia malayi TAR-binding protein 0.0065 0.0065 0.0078
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.107 0.1984 0.2394
Plasmodium falciparum calpain 0.0476 0.0851 0.2514
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0017 0.0047
Entamoeba histolytica cysteine protease, putative 0.0431 0.0764 0.2256
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.001 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1648 0.3089 0.9153
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0122 0.0175 0.0173
Loa Loa (eye worm) hypothetical protein 0.0431 0.0764 0.0922
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0431 0.0764 0.0921
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0039 0.0015 0.003
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0065 0.0078
Brugia malayi Calcium binding EGF domain containing protein 0.0042 0.0021 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0189 0.0302 0.03
Brugia malayi Papain family cysteine protease containing protein 0.0985 0.1822 0.22
Trypanosoma brucei cysteine peptidase C (CPC) 0.1648 0.3089 0.7364
Loa Loa (eye worm) G-protein coupled receptor 0.0189 0.0302 0.0364
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0009 0.002
Leishmania major phospholipase c-like protein 0.0195 0.0313 0.0742
Trypanosoma brucei hypothetical protein, conserved 0.0364 0.0637 0.1513
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0431 0.0764 0.2261
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0015 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0033
Trypanosoma cruzi metacaspase, putative 0.0043 0.0023 0.0024
Echinococcus multilocularis survival motor neuron protein 1 0.0478 0.0854 0.0853
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.001 0.5
Loa Loa (eye worm) hypothetical protein 0.0761 0.1394 0.1683
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0159 0.0245 0.0292
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0037 0.0044
Trichomonas vaginalis calmodulin, putative 0.023 0.0379 0.1121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0431 0.0764 0.2261
Schistosoma mansoni cpg binding protein 0.0093 0.0118 0.0142
Schistosoma mansoni cathepsin F (C01 family) 0.1797 0.3374 0.4074
Leishmania major cathepsin L-like protease 0.2226 0.4194 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0329 0.0568 0.135
Onchocerca volvulus Cathepsin L homolog 0.1797 0.3374 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0019
Echinococcus multilocularis sex peptide receptor 0.0189 0.0302 0.03
Loa Loa (eye worm) hypothetical protein 0.0058 0.0051 0.0062
Toxoplasma gondii histone lysine methyltransferase SET1 0.0175 0.0275 0.0807
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0379 0.1121
Trypanosoma cruzi calmodulin, putative 0.0195 0.0313 0.0375
Echinococcus multilocularis EF hand domain containing family member A2 0.0195 0.0313 0.0312
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0012 0.0011
Leishmania major calpain protease-like protein 0.0476 0.0851 0.2024
Entamoeba histolytica cysteine protease, putative 0.0431 0.0764 0.2256
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0003 0.0003
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0195 0.0313 0.0377
Toxoplasma gondii ABC1 family protein 0.0039 0.0016 0.0039
Schistosoma mansoni cathepsin C 0.0431 0.0764 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0034 0.0006 0.0018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0329 0.0568 0.0684
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0431 0.0764 0.2261
Loa Loa (eye worm) hypothetical protein 0.0042 0.0021 0.0025
Brugia malayi hypothetical protein 0.0034 0.0006 0.0008
Plasmodium falciparum serine repeat antigen 6 0.0431 0.0764 0.2256
Entamoeba histolytica prolyl oligopeptidase family protein 0.008 0.0093 0.0266
Echinococcus multilocularis thioredoxin glutathione reductase 0.0104 0.014 0.0138
Echinococcus granulosus histone lysine methyltransferase setb 0.0125 0.0179 0.0178
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0052 0.004 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0089 0.011 0.013
Echinococcus granulosus proteasome prosome macropain subunit beta 0.005 0.0037 0.0035
Brugia malayi Pre-SET motif family protein 0.0125 0.0179 0.0216
Schistosoma mansoni calpain-2 (C02 family) 0.0476 0.0851 0.1026
Echinococcus granulosus calpain 0.1248 0.2325 0.2324
Trypanosoma cruzi cysteine peptidase, putative 0.0985 0.1822 0.2198
Loa Loa (eye worm) hypothetical protein 0.2494 0.4705 0.5682
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.001 0.002
Plasmodium falciparum prefoldin subunit 6, putative 0.0066 0.0067 0.019
Brugia malayi aspartic protease BmAsp-1, identical 0.0052 0.004 0.0048
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0167 0.0166
Loa Loa (eye worm) CYP4Cod1 0.0068 0.0071 0.0086
Schistosoma mansoni caspase-7 (C14 family) 0.0083 0.0099 0.0118
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0037 0.0036
Leishmania major centrin, putative 0.0195 0.0313 0.0742
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0003 0.0003
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0189 0.0302 0.0364
Schistosoma mansoni centrin-related 0.0195 0.0313 0.0377
Schistosoma mansoni hypothetical protein 0.0189 0.0302 0.0363
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.005 0.0037 0.0099
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0159 0.0245 0.0722
Brugia malayi beta-lactamase family protein 0.0039 0.0016 0.0019
Mycobacterium ulcerans hypothetical protein 0.007 0.0075 0.1399
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.107 0.1984 0.4728
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0037 0.0109
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3165 0.5988 0.7231
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0985 0.1822 0.2199
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0189 0.0302 0.0364
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0009 0.0025
Onchocerca volvulus 0.0045 0.0027 0.0079
Loa Loa (eye worm) aspartyl protease 6 0.0052 0.004 0.0048
Leishmania major calmodulin, putative 0.0195 0.0313 0.0742
Echinococcus granulosus neuropeptides capa receptor 0.0189 0.0302 0.03
Onchocerca volvulus 0.0109 0.0149 0.0441
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.0169 0.3222
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0238 0.0394 0.3165
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.001 0.0019
Onchocerca volvulus 0.0097 0.0127 0.0375
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0022 0.0021
Leishmania major hypothetical protein, conserved 0.02 0.0322 0.0762
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0189 0.0302 0.03
Plasmodium vivax proteasome subunit beta type-2, putative 0.005 0.0037 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0364 0.0637 0.0766
Brugia malayi Proteasome A-type and B-type family protein 0.0159 0.0245 0.0295
Onchocerca volvulus 0.0045 0.0027 0.0079
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0681 0.1242 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0043 0.0023 0.006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0141 0.021 0.062
Loa Loa (eye worm) transcriptional regulator 0.0128 0.0184 0.0222
Echinococcus granulosus calpain 7 C02 family 0.1248 0.2325 0.2324
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0189 0.0302 0.03
Echinococcus granulosus chromatin regulatory protein sir2 0.0128 0.0184 0.0183
Echinococcus granulosus allatostatin A receptor 0.0189 0.0302 0.03
Schistosoma mansoni cercarial elastase (S01 family) 0.0123 0.0176 0.0211
Brugia malayi calpain family protein 1 0.297 0.5615 0.6781
Brugia malayi G-protein coupled receptor 0.0189 0.0302 0.0364
Echinococcus granulosus glycoprotein Antigen 5 0.0123 0.0176 0.0175
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0189 0.0302 0.0363
Giardia lamblia Cathepsin L-like protease 0.0431 0.0764 0.2465
Leishmania major prefoldin subunit, putative 0.0066 0.0067 0.0155
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0012 0.0013
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0027 0.0033
Schistosoma mansoni thyroid hormone receptor 0.0188 0.03 0.0361
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Onchocerca volvulus Chorion peroxidase homolog 0.0109 0.0149 0.0441
Onchocerca volvulus Cell death protein 3 homolog 0.0083 0.0099 0.0291
Schistosoma mansoni microtubule-associated protein tau 0.1336 0.2494 0.3011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0015
Brugia malayi proteasome subunit beta type 2 0.005 0.0037 0.0044
Trypanosoma brucei metacaspase 0.0043 0.0023 0.0048
Echinococcus multilocularis 0.0032 0.0003 0.0001
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0128 0.0184 0.0543
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0225 0.037 0.0877
Toxoplasma gondii histone deacetylase SIR2-like 0.0033 0.0003 0.0002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0009 0.0008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0043 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0155 0.0236 0.0286
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0189 0.0302 0.0363
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0189 0.0302 0.0363
Schistosoma mansoni hypothetical protein 0.0189 0.0302 0.0363
Toxoplasma gondii aspartyl protease 0.0052 0.004 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0093 0.0109
Brugia malayi hypothetical protein 0.0478 0.0854 0.1031
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.001 0.0017
Mycobacterium leprae putative cytochrome p450 0.0032 0.0003 0.0007
Onchocerca volvulus Cathepsin L homolog 0.0431 0.0764 0.2263
Echinococcus multilocularis cathepsin L 0.0985 0.1822 0.1821
Brugia malayi steroid hormone receptor 0.0051 0.0037 0.0045
Echinococcus multilocularis enteropeptidase 0.0123 0.0176 0.0175
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0122 0.0175 0.0209
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0682 0.1243 0.2961
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.0169 0.0397
Toxoplasma gondii hypothetical protein 0.008 0.0093 0.0269
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0701 0.128 0.1544
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0985 0.1822 0.4342
Giardia lamblia Alanyl dipeptidyl peptidase 0.008 0.0093 0.0291
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0701 0.128 0.1544
Brugia malayi hypothetical protein 0.0123 0.0176 0.0212
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0012 0.0015
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1248 0.2325 0.2805
Onchocerca volvulus Peroxidasin homolog 0.0109 0.0149 0.0441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1797 0.3374 1
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0042 0.0116
Brugia malayi Calmodulin-like protein 0.0195 0.0313 0.0378
Brugia malayi nuclear receptor NHR-88 0.0051 0.0037 0.0045
Trypanosoma cruzi cysteine peptidase, putative 0.2226 0.4194 0.5063
Toxoplasma gondii microneme protein, putative 0.0045 0.0027 0.0073
Loa Loa (eye worm) hypothetical protein 0.297 0.5615 0.6781
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0037 0.0045
Trichomonas vaginalis centrin, putative 0.0034 0.0006 0.0016
Schistosoma mansoni hypothetical protein 0.0476 0.0851 0.1026
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0003 0.0003
Trichomonas vaginalis calmodulin, putative 0.0034 0.0006 0.0016
Plasmodium falciparum proteasome subunit beta type-2, putative 0.005 0.0037 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0189 0.0302 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1243 0.2316 0.6863
Schistosoma mansoni reticulocalbin 0.02 0.0322 0.0387
Leishmania major silent information regulator 2, putative 0.0128 0.0184 0.0434
Brugia malayi PAN domain containing protein 0.0045 0.0027 0.0033
Entamoeba histolytica prefoldin subunit 6, putative 0.0066 0.0067 0.019
Leishmania major programmed cell death 6 protein-like protein 0.0195 0.0313 0.0742
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0149 0.018
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0045
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0037 0.0036
Plasmodium falciparum centrin-4 0.0034 0.0006 0.0009
Loa Loa (eye worm) calpain 5 0.0771 0.1414 0.1708
Echinococcus granulosus dna polymerase eta 0.0049 0.0034 0.0033
Brugia malayi hypothetical protein 0.0053 0.0042 0.0051
Toxoplasma gondii centrin, putative 0.0195 0.0313 0.0922
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.008 0.0093 0.0111
Loa Loa (eye worm) hypothetical protein 0.0189 0.0302 0.0364
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0012 0.0015
Schistosoma mansoni neuropeptide receptor 0.0189 0.0302 0.0363
Echinococcus granulosus g protein coupled receptor 0.0189 0.0302 0.03
Entamoeba histolytica cysteine protease, putative 0.0985 0.1822 0.5396
Echinococcus granulosus prefoldin subunit 6 0.0066 0.0067 0.0066

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.1 uM In vitro inhibitory concentration against Chymotrypsin-like activity of the purified human placenta 20S Proteasome ChEMBL. 11392545
IC50 (functional) = 1.1 uM In vitro inhibitory concentration against Chymotrypsin-like activity of the purified human placenta 20S Proteasome ChEMBL. 11392545

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11392545

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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