Detailed information for compound 348726

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 435.423 | Formula: C19H16F3N5O2S
  • H donors: 1 H acceptors: 5 LogP: 3.76 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1c(NCc2ccc(cc2)C)n(nc1C(F)(F)F)c1ccc(cn1)S(=O)(=O)C
  • InChi: 1S/C19H16F3N5O2S/c1-12-3-5-13(6-4-12)10-25-18-15(9-23)17(19(20,21)22)26-27(18)16-8-7-14(11-24-16)30(2,28)29/h3-8,11,25H,10H2,1-2H3
  • InChiKey: AGZUSBYIOAVFOC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Canis lupus familiaris Cyclooxygenase-2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0041 0.0048 0.007
Loa Loa (eye worm) hypothetical protein 0.0357 0.0667 0.0973
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Leishmania major hypothetical protein, conserved 0.004 0.0047 0.0118
Plasmodium falciparum cysteine proteinase falcipain 1 0.0822 0.1576 0.5415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0357 0.0667 0.2281
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0894 0.1718 0.4675
Loa Loa (eye worm) hypothetical protein 0.0151 0.0265 0.0386
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.003 0.003
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0067 0.0091
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0083 0.013 0.013
Brugia malayi hypothetical protein 0.0053 0.0073 0.01
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0033 0.0047
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0083
Loa Loa (eye worm) hypothetical protein 0.0357 0.0667 0.0973
Schistosoma mansoni pyruvate kinase 0.0033 0.0033 0.0047
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0004 0.0011
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0013 0.0031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.013 0.013
Plasmodium falciparum metacaspase 1 0.0044 0.0053 0.0179
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0162 0.0286 0.0285
Echinococcus granulosus calpain A 0.2389 0.4642 0.4642
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0095
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0293 0.0542 0.1468
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Leishmania major proteasome beta 5 subunit, putative 0.0146 0.0254 0.0682
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0063 0.0092 0.0092
Trypanosoma brucei Calpain-like protein 2 0.077 0.1476 0.4015
Trypanosoma brucei centrin, putative 0.0151 0.0265 0.071
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0039 0.0134
Loa Loa (eye worm) hypothetical protein 0.0066 0.0098 0.0142
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.003 0.01
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0151 0.0265 0.0386
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Echinococcus granulosus calmodulin 0.0151 0.0265 0.0264
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0061
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0051 0.0069 0.0231
Brugia malayi putative neuropeptide receptor 0.0083 0.013 0.0184
Schistosoma mansoni calmodulin 0.0151 0.0265 0.0386
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0048 0.0048
Giardia lamblia Cathepsin B precursor 0.1334 0.2579 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Loa Loa (eye worm) hypothetical protein 0.0151 0.0265 0.0386
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma brucei metacaspase 0.0044 0.0053 0.0134
Echinococcus granulosus neuropeptide FF receptor 2 0.0083 0.013 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Echinococcus granulosus Smad4 0.0025 0.0018 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.0455 0.0454
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0039 0.0719
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1039 0.2001 0.6871
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Schistosoma mansoni pyruvate kinase 0.0017 0.0001 0.0001
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0398 0.0748 0.2029
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0039 0.0094
Loa Loa (eye worm) transcriptional regulator 0.0032 0.003 0.0044
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0033 0.0041
Leishmania major small myristoylated protein-1 0.0399 0.075 0.2034
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.013 0.019
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.003 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.001 0.0009
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0095
Plasmodium vivax serine-repeat antigen (SERA) 0.0357 0.0667 0.2292
Trypanosoma cruzi kinesin, putative 0.0576 0.1096 0.1595
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0011 0.001
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0629 0.12 0.3262
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.003 0.0038
Schistosoma mansoni survival motor neuron protein 0.0051 0.0067 0.0098
Brugia malayi Cell death protein 3 precursor 0.0084 0.0133 0.0189
Trypanosoma cruzi calmodulin, putative 0.0151 0.0265 0.038
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0035 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0099 0.0144
Loa Loa (eye worm) hypothetical protein 0.0357 0.0667 0.0973
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Schistosoma mansoni hypothetical protein 0.0024 0.0015 0.0021
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0088 0.014 0.0198
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0047 0.0898
Echinococcus multilocularis g protein coupled receptor 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Giardia lamblia Cathepsin L-like protease 0.0357 0.0667 0.2582
Trichomonas vaginalis calpain, putative 0.0398 0.0747 0.2555
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0011 0.0017
Echinococcus multilocularis fmrfamide receptor 0.0083 0.013 0.013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0629 0.12 0.1746
Toxoplasma gondii kringle domain-containing protein 0.0066 0.0098 0.0333
Schistosoma mansoni cpg binding protein 0.0091 0.0146 0.0212
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0754 0.1444 0.3929
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1186 0.2289 0.3337
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.003 0.0029
Toxoplasma gondii calmodulin, putative 0.0028 0.0024 0.0076
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.001 0.0014
Echinococcus granulosus caspase 0.0115 0.0193 0.0192
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2385 0.4634 0.4634
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.003 0.009
Echinococcus multilocularis cathepsin L 0.0357 0.0667 0.0667
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.001 0.0014
Schistosoma mansoni chromobox protein 0.0069 0.0104 0.0151
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.002 0.0023
Loa Loa (eye worm) transcription factor SMAD2 0.037 0.0693 0.1011
Plasmodium falciparum serine repeat antigen 2 0.0357 0.0667 0.2289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Schistosoma mansoni hypothetical protein 0.0031 0.003 0.0043
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.005
Brugia malayi Cathepsin L-like precursor 0.0465 0.0878 0.1275
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0047 0.0898
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0083 0.013 0.013
Trypanosoma brucei calpain-like protein, putative 0.0974 0.1875 0.5103
Leishmania major small myristoylated protein-3, putative 0.0338 0.063 0.1708
Brugia malayi EF hand family protein 0.0155 0.0272 0.0392
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0083 0.013 0.019
Entamoeba histolytica hypothetical protein 0.0357 0.0667 0.2281
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.005 0.0159
Giardia lamblia Cathepsin L precursor 0.0357 0.0667 0.2582
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1503 0.291 0.291
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0137 0.0236 0.0235
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0033 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Schistosoma mansoni biogenic amine (5HT) receptor 0.0083 0.013 0.019
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0042
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.003 0.1044
Brugia malayi putative neuropeptide receptor NPR1 0.0083 0.013 0.0184
Schistosoma mansoni histamine h1 receptor 0.0083 0.013 0.019
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0073 0.025
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0069
Loa Loa (eye worm) hypothetical protein 0.0068 0.0101 0.0147
Echinococcus multilocularis Calcium binding protein 0.0028 0.0024 0.0023
Onchocerca volvulus Arrow homolog 0.0026 0.002 0.0053
Entamoeba histolytica protein kinase, putative 0.0576 0.1096 0.3758
Plasmodium vivax aspartyl proteinase, putative 0.0162 0.0286 0.0982
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0104 0.0342
Echinococcus granulosus alpha 1A adrenergic receptor 0.0083 0.013 0.013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0238 0.0433 0.8921
Loa Loa (eye worm) hypothetical protein 0.0051 0.0069 0.0099
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Entamoeba histolytica cysteine proteinase, putative 0.1503 0.291 1
Entamoeba histolytica cysteine proteinase 2 0.0822 0.1576 0.541
Brugia malayi cathepsin Z-like cysteine proteinase 0.0357 0.0667 0.0968
Trichomonas vaginalis centrin, putative 0.0151 0.0265 0.0896
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0338 0.063 0.0914
Loa Loa (eye worm) hypothetical protein 0.0357 0.0667 0.0973
Loa Loa (eye worm) MH2 domain-containing protein 0.037 0.0693 0.1011
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0028 0.0024 0.0065
Schistosoma mansoni myosin xvIII 0.0083 0.013 0.019
Echinococcus multilocularis dnaJ subfamily B 0.0803 0.154 0.1539
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0029 0.0026 0.0037
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0146 0.0254 0.0371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0822 0.1576 0.4289
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.001 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0053 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0357 0.0667 0.2281
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0357 0.0667 0.2292
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.1039 0.2001 0.6871
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.0009
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0039 0.0129
Giardia lamblia Cathepsin L precursor 0.0357 0.0667 0.2582
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0609 0.1161 0.3155
Echinococcus multilocularis cysteine protease 0.1503 0.291 0.291
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0039 0.0094
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.013 0.013
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0146 0.0254 0.0371
Schistosoma mansoni Smad4 0.0025 0.0018 0.0025
Trypanosoma brucei calmodulin, putative 0.0151 0.0265 0.071
Toxoplasma gondii thioredoxin reductase 0.0104 0.0172 0.0587
Leishmania major hypothetical protein, conserved 0.0053 0.0073 0.0187
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0043
Trichomonas vaginalis centrin, putative 0.0151 0.0265 0.0896
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0039 0.1383
Trypanosoma cruzi metacaspase, putative 0.0044 0.0053 0.0072
Entamoeba histolytica calmodulin, putative 0.0151 0.0265 0.0896
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0015 0.0014
Schistosoma mansoni hypothetical protein 0.0141 0.0245 0.0357
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0067 0.0092
Loa Loa (eye worm) hypothetical protein 0.0465 0.0878 0.128
Loa Loa (eye worm) hypothetical protein 0.1503 0.291 0.4247
Onchocerca volvulus 0.1503 0.291 1
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0123 0.021 0.03
Brugia malayi Animal haem peroxidase family protein 0.016 0.0281 0.0404
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.079 0.1515 0.2206
Loa Loa (eye worm) matrixin family protein 0.0059 0.0083 0.0121
Loa Loa (eye worm) hypothetical protein 0.1657 0.321 0.4686
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.001 0.0014
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.003 0.003
Brugia malayi Kringle domain containing protein 0.0066 0.0098 0.0137
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0033 0.0077
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0398 0.0747 0.2555
Plasmodium vivax unspecified product 0.0822 0.1576 0.5417
Echinococcus granulosus cathepsin l1 0.1503 0.291 0.291
Onchocerca volvulus 0.1503 0.291 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0083 0.013 0.0184
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0031
Trichomonas vaginalis calcium binding protein, putative 0.0028 0.0024 0.0066
Schistosoma mansoni adenoreceptor 0.0083 0.013 0.019
Plasmodium falciparum plasmepsin II 0.0162 0.0286 0.0978
Onchocerca volvulus 0.0088 0.014 0.0465
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0083 0.013 0.013
Brugia malayi Pepsin A precursor 0.0051 0.0069 0.0094
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Giardia lamblia Cysteine protease 0.0357 0.0667 0.2582
Trypanosoma brucei hypothetical protein 0.0691 0.1321 0.3593
Onchocerca volvulus 0.1503 0.291 1
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.002 0.0029
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0044 0.0145
Brugia malayi EF hand family protein 0.0151 0.0265 0.038
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0083 0.013 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0822 0.1576 0.4289
Brugia malayi Cathepsin L-like precursor 0.1503 0.291 0.4244
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0398 0.0747 0.2563
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0083 0.013 0.019
Echinococcus granulosus peroxidasin 0.016 0.0281 0.028
Onchocerca volvulus 0.0051 0.0067 0.0216
Echinococcus granulosus prefoldin subunit 6 0.0066 0.0098 0.0097
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0047 0.0898
Brugia malayi hypothetical protein 0.0158 0.0278 0.0399
Onchocerca volvulus Cathepsin F homolog 0.1503 0.291 1
Echinococcus granulosus calpain 5 0.0974 0.1875 0.1874
Schistosoma mansoni neuropeptide receptor 0.0083 0.013 0.019
Schistosoma mansoni peroxidasin 0.016 0.0281 0.0409
Giardia lamblia Cathepsin L precursor 0.0357 0.0667 0.2582
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0146 0.0254 0.0981
Plasmodium falciparum serine repeat antigen 5 0.0357 0.0667 0.2289
Loa Loa (eye worm) hypothetical protein 0.0398 0.0747 0.109
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0083
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0034
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.003 0.003
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Entamoeba histolytica cysteine proteinase, putative 0.1503 0.291 1
Trypanosoma brucei caltractin, putative 0.018 0.032 0.0861
Brugia malayi transcriptional regulator, Sir2 family protein 0.0123 0.021 0.03
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma cruzi I/6 autoantigen, putative 0.0151 0.0265 0.038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1268 0.2449 0.3571
Schistosoma mansoni calpain (C02 family) 0.0974 0.1875 0.2736
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Onchocerca volvulus 0.0083 0.013 0.0432
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Mycobacterium leprae conserved hypothetical protein 0.004 0.0047 0.0466
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0088 0.014 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Giardia lamblia Cathepsin B precursor 0.0357 0.0667 0.2582
Onchocerca volvulus 0.0083 0.013 0.0432
Echinococcus multilocularis microtubule associated protein 2 0.0681 0.1301 0.1301
Onchocerca volvulus 0.0031 0.0029 0.0084
Echinococcus multilocularis tachykinin peptides receptor 99D 0.5127 1 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0265 0.0896
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.003 0.0029
Leishmania major META domain containing protein 0.0232 0.0421 0.1138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0009 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0073 0.01
Toxoplasma gondii hypothetical protein 0.0398 0.0747 0.2563
Plasmodium falciparum thioredoxin reductase 0.0036 0.0039 0.0129
Onchocerca volvulus Dual oxidase homolog 0.016 0.0281 0.095
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0357 0.0667 0.2281
Echinococcus granulosus caspase 8 0.0044 0.0053 0.0053
Brugia malayi calcium-binding protein 0.0151 0.0265 0.038
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0015 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0047 0.0898
Schistosoma mansoni hypothetical protein 0.0088 0.014 0.0203
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0083 0.013 0.013
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0033 0.0098
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0226 0.0411 0.06
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0629 0.12 0.1746
Brugia malayi cathepsin L-like cysteine proteinase 0.0357 0.0667 0.0968
Leishmania major hypothetical protein, conserved 0.0639 0.1219 0.3315
Echinococcus granulosus peptide allatostatin:somatostatin 0.0083 0.013 0.013
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0822 0.1576 0.2301
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Loa Loa (eye worm) EF hand family protein 0.0151 0.0265 0.0386
Trypanosoma brucei calpain, putative 0.0691 0.1321 0.3593
Brugia malayi Neuronal calcium sensor family protein 1 0.0028 0.0024 0.0028
Leishmania major hypothetical protein, conserved 0.0375 0.0702 0.1904
Trichomonas vaginalis calpain, putative 0.0398 0.0747 0.2555
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0357 0.0667 0.2281
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0822 0.1576 0.2296
Toxoplasma gondii calmodulin CAM2 0.0028 0.0024 0.0076
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0016 0.0022
Brugia malayi Cytochrome P450 family protein 0.0034 0.0035 0.0045
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3517 0.685 1
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0232 0.0421 0.1138
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0095
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0069
Echinococcus multilocularis sex peptide receptor 0.0083 0.013 0.013
Onchocerca volvulus 0.0088 0.014 0.0465
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.013 0.019
Leishmania major small myristoylated protein 4, putative 0.0629 0.12 0.3262
Echinococcus granulosus dna polymerase eta 0.005 0.0067 0.0066
Entamoeba histolytica grainin 2 0.018 0.032 0.1086
Brugia malayi proteasome subunit beta type 1 0.0063 0.0092 0.0128
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0629 0.12 0.1746
Mycobacterium tuberculosis Probable dehydrogenase 0.0238 0.0433 0.8921
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0069
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.0667 0.0973
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.0667 0.0973
Leishmania major hypothetical protein, conserved 0.0155 0.0272 0.0731
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2233 0.4338 0.6332
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0024 0.0028
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0011 0.0009
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0067 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0822 0.1576 0.541
Giardia lamblia Encystation-specific protease 0.0357 0.0667 0.2582
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.003 0.0029
Brugia malayi Pre-SET motif family protein 0.0068 0.0101 0.0142
Plasmodium falciparum plasmepsin V 0.0051 0.0069 0.0231
Schistosoma mansoni egf-like domain protein 0.0026 0.002 0.0029
Toxoplasma gondii centrin, putative 0.0151 0.0265 0.0905
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0065 0.0096 0.0134
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.013 0.019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1503 0.291 0.4247
Leishmania major DNA polymerase eta, putative 0.0035 0.0037 0.009
Toxoplasma gondii ABC1 family protein 0.004 0.0047 0.0159
Brugia malayi beta-lactamase family protein 0.004 0.0047 0.0063
Echinococcus multilocularis programmed cell death protein 6 0.0032 0.0031 0.0031
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0083 0.013 0.019
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0063 0.0092 0.0128
Schistosoma mansoni calmodulin 0.0151 0.0265 0.0386
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Schistosoma mansoni caspase-7 (C14 family) 0.0084 0.0133 0.0194
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0025 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0101 0.0147
Brugia malayi aspartic protease BmAsp-2, identical 0.0051 0.0069 0.0094
Brugia malayi neuropeptide F receptor 0.0083 0.013 0.0184
Echinococcus granulosus EF hand domain containing family member A2 0.0155 0.0272 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Trypanosoma brucei I/6 autoantigen 0.0151 0.0265 0.071
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.003 0.0543
Toxoplasma gondii prefoldin subunit 6, putative 0.0066 0.0098 0.0331
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.003 0.009
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0051 0.0067 0.0098
Schistosoma mansoni hypothetical protein 0.0031 0.003 0.0043
Mycobacterium leprae Probable lipase LipE 0.004 0.0047 0.0466
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0083 0.013 0.013
Echinococcus multilocularis caspase 2 0.0084 0.0133 0.0133
Brugia malayi chromobox protein homolog 3 0.0039 0.0044 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0357 0.0667 0.2281
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0162 0.0236
Trypanosoma cruzi hypothetical protein, conserved 0.0232 0.0421 0.0609
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.005 0.0173
Echinococcus granulosus Myosin regulatory light chain 0.0028 0.0024 0.0023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0039 0.0038
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Echinococcus multilocularis fibrillin 1 0.0029 0.0026 0.0025
Schistosoma mansoni hypothetical protein 0.0031 0.003 0.0043
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0018 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.001 0.0009
Toxoplasma gondii cathepsin CPL 0.1503 0.291 1
Plasmodium vivax unspecified product 0.0357 0.0667 0.2292
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1942 0.5287
Echinococcus multilocularis dna polymerase eta 0.005 0.0067 0.0066
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0357 0.0667 0.2292
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.013 0.019
Trypanosoma cruzi metacaspase, putative 0.0044 0.0053 0.0072
Schistosoma mansoni neuropeptide receptor 0.0083 0.013 0.019
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Echinococcus multilocularis glycoprotein Antigen 5 0.0088 0.014 0.0139
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0238 0.0433 0.8921
Loa Loa (eye worm) aspartyl protease 6 0.0051 0.0069 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0053 0.0169
Echinococcus granulosus enteropeptidase 0.0088 0.014 0.0139
Schistosoma mansoni hypothetical protein 0.0031 0.003 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0019 0.0005 0.000000030195
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0011 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0101 0.0147
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.013 0.019
Leishmania major small myristoylated protein-2 0.0728 0.1392 0.3787
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.079 0.1515 0.4121
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0047 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0018 0.0017
Echinococcus multilocularis EF hand domain containing family member A2 0.0155 0.0272 0.0272
Schistosoma mansoni notch 0.0019 0.0005 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0104 0.0342
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0019 0.0005 0.0001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0083 0.013 0.019
Leishmania major hypothetical protein, conserved 0.0066 0.0098 0.0256
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0083 0.013 0.013
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0011 0.0015
Toxoplasma gondii troponin c, isotype gamma, putative 0.0151 0.0265 0.0905
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Schistosoma mansoni chromatin regulatory protein sir2 0.0123 0.021 0.0306
Echinococcus granulosus cathepsin b 0.3517 0.685 0.685
Entamoeba histolytica cysteine proteinase, putative 0.0822 0.1576 0.541
Trypanosoma brucei Calpain-like protein CALP1.3 0.0629 0.12 0.3262
Echinococcus granulosus cathepsin L cysteine proteinase 0.1503 0.291 0.291
Schistosoma mansoni hypothetical protein 0.0861 0.1653 0.2412
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0022
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0083 0.013 0.019
Brugia malayi hypothetical protein 0.0034 0.0036 0.0046
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Brugia malayi follicle stimulating hormone receptor 0.0083 0.013 0.0184
Echinococcus multilocularis programmed cell death protein 0.018 0.032 0.0319
Brugia malayi cathepsin F-like cysteine proteinase 0.0357 0.0667 0.0968
Onchocerca volvulus 0.0024 0.0016 0.0038
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0357 0.0667 0.0973
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0242 0.0441 0.0441
Schistosoma mansoni DNA polymerase eta 0.005 0.0067 0.0097
Echinococcus granulosus bloom syndrome protein 0.0024 0.0015 0.0015
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0162 0.0286 0.0969
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.003 0.0044
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0018 0.0017
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0083 0.012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0822 0.1576 0.2301
Loa Loa (eye worm) hypothetical protein 0.0066 0.0098 0.0143
Brugia malayi Thioredoxin reductase 0.0104 0.0172 0.0245
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0031
Onchocerca volvulus 0.0083 0.013 0.0432
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0047 0.0148
Echinococcus multilocularis pyruvate kinase 0.0033 0.0033 0.0032
Echinococcus multilocularis neurogenic locus notch protein 0.0019 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0083 0.012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0357 0.0667 0.2281
Echinococcus granulosus neuropeptide receptor 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0057 0.0081 0.0117
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0151 0.0265 0.0896
Giardia lamblia Transcriptional regulator, Sir2 family 0.0032 0.003 0.0113
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0293 0.0542 0.0786
Loa Loa (eye worm) transcriptional regulator 0.0032 0.003 0.0044
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.0247 0.0247
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0629 0.12 0.3262
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0151 0.0265 0.038
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0357 0.0667 0.2292
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.013 0.013
Echinococcus multilocularis allatostatin A receptor 0.0083 0.013 0.013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.013 0.019
Brugia malayi cathepsin F-like cysteine proteinase 0.0465 0.0878 0.1275
Giardia lamblia Cathepsin B precursor 0.0357 0.0667 0.2582
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1334 0.2579 0.3765
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0265 0.0896
Echinococcus multilocularis cysteine protease 0.1503 0.291 0.291
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0629 0.12 0.1746
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0047 0.0069
Schistosoma mansoni rab 0.0151 0.0265 0.0386
Echinococcus granulosus cathepsin L 0.0357 0.0667 0.0667
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0008 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.013 0.019
Giardia lamblia Cysteine protease 0.0357 0.0667 0.2582
Brugia malayi cathepsin L precursor 0.0357 0.0667 0.0968
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0053 0.0072
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0099 0.0144
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.001 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0011 0.0023
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0088 0.014 0.0203
Echinococcus granulosus Calcium binding protein 0.0028 0.0024 0.0023
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0053 0.0179
Echinococcus multilocularis hypothetical protein 0.0974 0.1875 0.1874
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0033 0.0096
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2385 0.4634 0.6765
Brugia malayi Papain family cysteine protease containing protein 0.0822 0.1576 0.2296
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0035 0.0051
Echinococcus multilocularis lamin dm0 0.0059 0.0083 0.0082
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0088 0.0141 0.014
Trichomonas vaginalis calcineurin B subunit, putative 0.0155 0.0272 0.0923
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Leishmania major protein kinase, putative 0.0151 0.0265 0.071
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0236 0.0796
Brugia malayi Probable myosin regulatory light chain 0.0032 0.0031 0.004
Echinococcus granulosus neuropeptide receptor 0.0083 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0044 0.0137
Onchocerca volvulus 0.0083 0.013 0.0432
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Trypanosoma cruzi cysteine proteinase, putative 0.0822 0.1576 0.2296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Brugia malayi steroid hormone receptor 0.0021 0.001 0.0009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Plasmodium falciparum serine repeat antigen 6 0.0357 0.0667 0.2289
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.001 0.001
Plasmodium vivax aspartyl protease, putative 0.0051 0.0069 0.0236
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0083 0.013 0.019
Entamoeba histolytica prefoldin subunit 6, putative 0.0066 0.0098 0.0322
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0063 0.0092 0.0312
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.0094
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1942 0.5287
Trichomonas vaginalis conserved hypothetical protein 0.0398 0.0747 0.2555
Trichomonas vaginalis helicase, putative 0.0019 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0357 0.0667 0.2281
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.0455 0.0454
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0024 0.0029
Brugia malayi Matrixin family protein 0.0024 0.0016 0.0017
Plasmodium falciparum centrin-1 0.0151 0.0265 0.0905
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0151 0.0265 0.0264
Schistosoma mansoni hypothetical protein 0.0398 0.0747 0.109
Entamoeba histolytica cysteine protease, putative 0.0357 0.0667 0.2281
Giardia lamblia Programmed cell death protein-like protein 0.0028 0.0024 0.0086
Leishmania major calmodulin-like protein 0.0151 0.0265 0.071
Schistosoma mansoni cathepsin C 0.0357 0.0667 0.0973
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Leishmania major cathepsin L-like protease 0.1891 0.3669 1
Schistosoma mansoni cathepsin F (C01 family) 0.1503 0.291 0.4247
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0264 0.0485 1
Onchocerca volvulus 0.1503 0.291 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0024 0.0023
Brugia malayi Serotonin receptor 0.0083 0.013 0.0184
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0047 0.0148
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0083 0.013 0.019
Echinococcus granulosus programmed cell death protein 0.018 0.032 0.0319
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.001 0.0014
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0611 0.1163 0.1693
Trypanosoma cruzi centrin, putative 0.018 0.032 0.0461
Schistosoma mansoni hypothetical protein 0.0083 0.013 0.019
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0037 0.0124
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0063 0.0092 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0357 0.0667 0.2281
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0338 0.063 0.0914
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0357 0.0667 0.2281
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0028 0.0024 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0083
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Leishmania major hypothetical protein, unknown function 0.0398 0.0747 0.2026
Echinococcus granulosus transmembrane protease serine 3 0.0088 0.014 0.0139
Brugia malayi beta-lactamase family protein 0.004 0.0047 0.0063
Schistosoma mansoni calmodulin-related 0.0028 0.0024 0.0034
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.003 0.0026 0.0453
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Trypanosoma cruzi cysteine peptidase, putative 0.0822 0.1576 0.2296
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1334 0.2579 0.3761
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.0009
Echinococcus granulosus calbindin 32 0.0155 0.0272 0.0272
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.013 0.013
Onchocerca volvulus 0.0151 0.0265 0.0894
Mycobacterium tuberculosis Conserved protein 0.004 0.0047 0.0898
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.096 0.1847 0.5028
Trichomonas vaginalis esterase, putative 0.004 0.0047 0.0148
Brugia malayi calpain 5 0.0398 0.0747 0.1085
Entamoeba histolytica cysteine protease, putative 0.0357 0.0667 0.2281
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0037
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.001 0.0014
Echinococcus multilocularis neuropeptide FF receptor 2 0.0083 0.013 0.013
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1268 0.2449 0.667
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0357 0.0667 0.0973
Loa Loa (eye worm) hypothetical protein 0.0357 0.0667 0.0973
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0353 0.0514
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.001 0.001
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0095
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0357 0.0667 0.2292
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0151 0.0265 0.0896
Trypanosoma cruzi cruzipain precursor, putative 0.1891 0.3669 0.5353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Loa Loa (eye worm) melatonin receptor type 1A 0.0083 0.013 0.019
Trypanosoma cruzi cysteine peptidase, putative 0.1891 0.3669 0.5353
Schistosoma mansoni caspase-7 (C14 family) 0.0115 0.0193 0.0281
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0009
Schistosoma mansoni calpain-7 (C02 family) 0.0974 0.1875 0.2736
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.005
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0083 0.013 0.0184
Loa Loa (eye worm) calpain 5 0.0576 0.1096 0.16
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0053 0.0169
Onchocerca volvulus 0.0051 0.0069 0.022
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0357 0.0667 0.2292
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0039 0.0094
Schistosoma mansoni cpg binding protein 0.0091 0.0146 0.0212
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.001 0.0009
Brugia malayi aspartic protease BmAsp-1, identical 0.0051 0.0069 0.0094
Schistosoma mansoni smad1 5 8 and 0.0025 0.0018 0.0025
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0146 0.0254 0.4973
Echinococcus multilocularis Tolloid protein 1 0.0091 0.0147 0.0146
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.005 0.0156
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.001
Echinococcus granulosus programmed cell death protein 6 0.0032 0.0031 0.0031
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0629 0.12 0.3262
Mycobacterium ulcerans beta-lactamase 0.004 0.0047 0.1726
Leishmania major calcineurin B subunit, putative 0.0151 0.0265 0.071
Echinococcus granulosus calpain 7 C02 family 0.0974 0.1875 0.1874
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Brugia malayi hypothetical protein 0.0041 0.0048 0.0064
Entamoeba histolytica grainin, putative 0.0155 0.0272 0.0923
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.003 0.009
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0033 0.0041
Schistosoma mansoni chromobox protein 0.0069 0.0104 0.0151
Schistosoma mansoni hypothetical protein 0.0034 0.0036 0.0051
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.003 0.1044
Loa Loa (eye worm) hypothetical protein 0.1835 0.3559 0.5196
Loa Loa (eye worm) hypothetical protein 0.2233 0.4338 0.6332
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.001 0.001
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0039 0.1383
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0398 0.0747 0.2555
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.001
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0033 0.0096
Brugia malayi sulfakinin receptor protein 0.0083 0.013 0.0184
Echinococcus granulosus cathepsin l1 0.1039 0.2001 0.2
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0099 0.0144
Echinococcus multilocularis sodium channel protein 0.004 0.0047 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0151 0.0265 0.071
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0039 0.0134
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Trypanosoma cruzi cysteine peptidase, putative 0.0465 0.0878 0.1275
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Schistosoma mansoni hypothetical protein 0.0088 0.014 0.0203
Schistosoma mansoni smad1 5 8 and 0.0025 0.0018 0.0025
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0039 0.0119
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0083 0.013 0.013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Onchocerca volvulus 0.0083 0.013 0.0432
Plasmodium vivax unspecified product 0.0465 0.0878 0.3016
Brugia malayi hypothetical protein 0.0051 0.0069 0.0094
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0465 0.0878 0.1275
Entamoeba histolytica cysteine proteinase, putative 0.0822 0.1576 0.541
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0044 0.0135
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0073 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0398 0.0747 0.2026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0009
Onchocerca volvulus 0.0357 0.0667 0.228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0822 0.1576 0.541
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.0247 0.0361
Echinococcus granulosus chromatin regulatory protein sir2 0.0123 0.021 0.021
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0123 0.021 0.03
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi Animal haem peroxidase family protein 0.016 0.0281 0.0404
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Onchocerca volvulus 0.0031 0.0029 0.0084
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.003 0.0071
Toxoplasma gondii hypothetical protein 0.0031 0.0029 0.0095
Echinococcus multilocularis caspase 8 0.0044 0.0053 0.0053
Giardia lamblia Cathepsin L-like protease 0.0357 0.0667 0.2582
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0083 0.013 0.019
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.003 0.0037
Echinococcus multilocularis Smad4 0.0025 0.0018 0.0017
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0099 0.0144
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1186 0.2289 0.3337
Onchocerca volvulus Matrix metalloproteinase homolog 0.0054 0.0074 0.0237
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0015 0.0014
Brugia malayi AKH receptor 0.0083 0.013 0.0184
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0155 0.0226
Trichomonas vaginalis calcium binding protein, putative 0.0151 0.0265 0.0896
Brugia malayi calpain family protein 1 0.2233 0.4338 0.633
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi hypothetical protein 0.0137 0.0236 0.0338
Echinococcus multilocularis serotonin receptor 0.0083 0.013 0.013
Leishmania major sir2-family protein-like protein 0.0032 0.003 0.0071
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0293 0.0542 0.1468
Toxoplasma gondii microneme protein MIC4 0.0031 0.0029 0.0095
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.013 0.013
Brugia malayi Pre-SET motif family protein 0.0463 0.0874 0.127
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Echinococcus granulosus somatostatin receptor 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1942 0.283
Brugia malayi nuclear hormone receptor 0.0021 0.001 0.0009
Trypanosoma brucei proteasome beta 6 subunit 0.0063 0.0092 0.024
Mycobacterium ulcerans hydrolase 0.003 0.0026 0.0871
Brugia malayi G protein-coupled receptor F59B2.13 0.0083 0.013 0.0184
Brugia malayi Animal haem peroxidase family protein 0.016 0.0281 0.0404
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0031 0.0029 0.0095
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.001 0.0014
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0039 0.005
Giardia lamblia Hypothetical protein 0.0155 0.0272 0.1051
Echinococcus granulosus Tolloid protein 1 0.0091 0.0147 0.0146
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0099 0.0144
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0232 0.0421 0.0609
Onchocerca volvulus 0.0083 0.013 0.0432
Loa Loa (eye worm) hypothetical protein 0.0153 0.0267 0.039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0353 0.0514
Trypanosoma cruzi unspecified product 0.0399 0.075 0.1089
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0128 0.0219 0.032
Echinococcus multilocularis cpg binding protein 0.0091 0.0146 0.0145
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0033 0.0047
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi Matrixin family protein 0.0059 0.0083 0.0115
Echinococcus granulosus cysteine protease 0.0822 0.1576 0.1576
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0357 0.0667 0.2281
Echinococcus granulosus G protein coupled receptor 139 0.0083 0.013 0.013
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0232 0.0421 0.1138
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0083
Echinococcus multilocularis EF hand domain containing family member A2 0.0151 0.0265 0.0264
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0236 0.0796
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0155 0.0272 0.0936
Plasmodium vivax centrin-1, putative 0.0151 0.0265 0.0909
Loa Loa (eye worm) hypothetical protein 0.0037 0.0041 0.0059
Onchocerca volvulus Cathepsin L homolog 0.1503 0.291 1
Trypanosoma cruzi hypothetical protein, conserved 0.0375 0.0702 0.1019
Echinococcus multilocularis neuropeptide s receptor 0.0417 0.0785 0.0785
Loa Loa (eye worm) thioredoxin reductase 0.0104 0.0172 0.0251
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.001 0.001
Plasmodium falciparum thioredoxin reductase 0.0104 0.0172 0.0587
Schistosoma mansoni growth hormone secretagogue receptor 0.0083 0.013 0.019
Trypanosoma cruzi calmodulin, putative 0.0151 0.0265 0.038
Trichomonas vaginalis kakapo, putative 0.0028 0.0024 0.0066
Plasmodium falciparum cysteine repeat modular protein 1 0.0066 0.0098 0.0333
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0691 0.1321 0.3593
Brugia malayi calpain 7 0.0974 0.1875 0.2732
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1503 0.291 1
Loa Loa (eye worm) animal heme peroxidase 0.016 0.0281 0.0409
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0047 0.1726
Loa Loa (eye worm) matrixin family protein 0.0054 0.0074 0.0107
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.001 0.0014
Loa Loa (eye worm) animal heme peroxidase 0.016 0.0281 0.0409
Plasmodium vivax vivapain-3 0.0822 0.1576 0.5417
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0039 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0353 0.0352
Echinococcus multilocularis neuropeptide receptor 0.0083 0.013 0.013
Brugia malayi Cytochrome P450 family protein 0.0034 0.0035 0.0045
Brugia malayi nuclear receptor NHR-88 0.0021 0.001 0.0009
Onchocerca volvulus Putative cubilin 0.0026 0.002 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0099 0.0144
Brugia malayi Animal haem peroxidase family protein 0.016 0.0281 0.0404
Loa Loa (eye worm) TK/ROR protein kinase 0.0066 0.0098 0.0143
Trypanosoma brucei centrin, putative 0.0151 0.0265 0.071
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.077 0.1476 0.4015
Mycobacterium tuberculosis Conserved protein 0.004 0.0047 0.0898
Toxoplasma gondii calmodulin CAM1 0.0155 0.0272 0.0932
Plasmodium falciparum serine repeat antigen 9 0.0357 0.0667 0.2289
Onchocerca volvulus 0.0083 0.013 0.0432
Trichomonas vaginalis calcium binding protein, putative 0.0151 0.0265 0.0896
Schistosoma mansoni smad1 5 8 and 0.0025 0.0018 0.0025
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0137 0.0236 0.0909
Onchocerca volvulus 0.0083 0.013 0.0432
Echinococcus granulosus sodium channel protein 0.004 0.0047 0.0046
Echinococcus granulosus calcium uptake protein 1 0.0155 0.0272 0.0272
Schistosoma mansoni pyruvate kinase 0.0033 0.0033 0.0047
Brugia malayi Smad1 0.0025 0.0018 0.0019
Onchocerca volvulus 0.0151 0.0265 0.0894
Echinococcus multilocularis muscleblind protein 0.0153 0.0267 0.0267
Brugia malayi Myosin regulatory light chain 1 0.0028 0.0024 0.0028
Brugia malayi Calmodulin-like protein 0.0151 0.0265 0.038
Schistosoma mansoni cathepsin s 0.0465 0.0878 0.128
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0028 0.0024 0.0081
Leishmania major calmodulin, putative 0.0151 0.0265 0.071
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0044 0.0164
Onchocerca volvulus 0.0031 0.0029 0.0084
Echinococcus granulosus cathepsin L cysteine protease 0.0822 0.1576 0.1576
Echinococcus multilocularis lamin 0.0059 0.0083 0.0082
Schistosoma mansoni nuclear hormone receptor 0.0021 0.001 0.0014
Leishmania major centrin, putative,caltractin, putative 0.0151 0.0265 0.071
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0609 0.1161 0.3155
Leishmania major programmed cell death 6 protein-like protein 0.0151 0.0265 0.071
Brugia malayi Cathepsin L-like precursor 0.1503 0.291 0.4244
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Plasmodium vivax aspartyl proteinase, putative 0.0051 0.0069 0.0236
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0609 0.1161 0.1689
Leishmania major cathepsin L-like protease 0.1503 0.291 0.7928
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0047 0.0898
Echinococcus multilocularis enteropeptidase 0.0088 0.014 0.0139
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0095
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0287 0.0418
Trypanosoma cruzi conserved protein 0.0639 0.1219 0.1775
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma cruzi cysteine peptidase, putative 0.1891 0.3669 0.5353
Plasmodium falciparum glutathione reductase 0.0104 0.0172 0.0587
Loa Loa (eye worm) hypothetical protein 0.0084 0.0133 0.0194
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0004 0.0004
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0162 0.0286 0.0285
Trichomonas vaginalis hypothetical protein 0.0398 0.0747 0.2555
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0123 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0539 0.1023 0.1488
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0357 0.0667 0.0973
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0018 0.0025
Echinococcus granulosus neuropeptide s receptor 0.0417 0.0785 0.0785
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0083
Loa Loa (eye worm) hypothetical protein 0.005 0.0067 0.0097
Onchocerca volvulus 0.0031 0.0029 0.0084
Onchocerca volvulus Matrilysin homolog 0.0054 0.0074 0.0237
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Schistosoma mansoni biogenic amine receptor 0.0083 0.013 0.019
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Trypanosoma cruzi centrin, putative 0.018 0.032 0.0461
Brugia malayi Hemopexin family protein 0.0034 0.0036 0.0046
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0015 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni ef hand domain family member A2 0.0151 0.0265 0.0386
Plasmodium vivax plasmepsin IV, putative 0.0162 0.0286 0.0982
Schistosoma mansoni centrin 0.0151 0.0265 0.0386
Leishmania major hypothetical protein, conserved 0.0232 0.0421 0.1138
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1334 0.2579 0.7026
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0232 0.0421 0.1138
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1727 0.3347 0.3346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0357 0.0667 0.2281
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.002 0.0023
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3517 0.685 1
Plasmodium vivax SET domain protein, putative 0.0068 0.0101 0.0348
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.003 0.009
Onchocerca volvulus 0.0083 0.013 0.0432
Loa Loa (eye worm) hypothetical protein 0.0465 0.0878 0.128
Echinococcus granulosus Mastin 0.0088 0.014 0.0139
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Toxoplasma gondii aspartyl protease ASP3 0.0051 0.0069 0.0231
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0063 0.0092 0.0302
Trichomonas vaginalis centrin, putative 0.0028 0.0024 0.0066
Echinococcus multilocularis GPCR, family 2 0.0031 0.003 0.0029
Entamoeba histolytica hypothetical protein, conserved 0.0155 0.0272 0.0923
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0073 0.0187
Brugia malayi Cytochrome P450 family protein 0.0035 0.0037 0.0048
Onchocerca volvulus 0.0028 0.0024 0.0065
Echinococcus multilocularis calcium uptake protein 1 0.0155 0.0272 0.0272
Entamoeba histolytica cysteine proteinase 1, putative 0.0822 0.1576 0.541
Echinococcus multilocularis calpain family protein 1, d 0.1657 0.321 0.321
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0236 0.0796
Echinococcus granulosus hypothetical protein 0.0083 0.013 0.013
Loa Loa (eye worm) TYRA-2 protein 0.0083 0.013 0.019
Schistosoma mansoni amine GPCR 0.0083 0.013 0.019
Trypanosoma cruzi hypothetical protein, conserved 0.0232 0.0421 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0357 0.0667 0.2281
Echinococcus granulosus pyruvate kinase 0.0033 0.0033 0.0032
Schistosoma mansoni ap endonuclease 0.0018 0.0004 0.0006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0338 0.063 0.0914
Plasmodium falciparum serine repeat antigen 4 0.0357 0.0667 0.2289
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Plasmodium falciparum calpain 0.0398 0.0747 0.2563
Mycobacterium ulcerans lipase LipD 0.004 0.0047 0.1726
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0099 0.0099
Onchocerca volvulus 0.0051 0.0069 0.022
Echinococcus multilocularis calpain A 0.2389 0.4642 0.4642
Onchocerca volvulus 0.0083 0.013 0.0432
Leishmania major silent information regulator 2, putative 0.0123 0.021 0.0561
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.0101 0.0344
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0034
Giardia lamblia Calmodulin 0.0028 0.0024 0.0086
Echinococcus granulosus neuronal calcium sensor 0.0151 0.0265 0.0264
Brugia malayi cathepsin L-like precursor 0.1039 0.2001 0.2916
Trichomonas vaginalis calcium binding protein, putative 0.018 0.032 0.1086
Echinococcus granulosus g protein coupled receptor 0.0083 0.013 0.013
Echinococcus multilocularis calpain 5 0.0974 0.1875 0.1874
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0264 0.0485 1
Giardia lamblia Hypothetical protein 0.0123 0.021 0.0809
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.013 0.013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0162 0.0286 0.0417
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.005
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0115 0.0193 0.0192
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0088 0.014 0.0203
Trypanosoma cruzi I/6 autoantigen, putative 0.0151 0.0265 0.038
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0073 0.01
Schistosoma mansoni neuropeptide f receptor 76f 0.0083 0.013 0.019
Schistosoma mansoni chromatin regulatory protein sir2 0.0123 0.021 0.0306
Echinococcus multilocularis fmrfamide receptor 0.0083 0.013 0.013
Giardia lamblia Proteasome subunit beta type 1 0.0063 0.0092 0.0352
Brugia malayi Animal haem peroxidase family protein 0.016 0.0281 0.0404
Loa Loa (eye worm) hypothetical protein 0.0105 0.0173 0.0253
Trypanosoma brucei small myristoylated protein 1-2 0.0399 0.075 0.2034
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0861 0.1653 0.2412
Leishmania major cathepsin L-like protease 0.1503 0.291 0.7928
Echinococcus granulosus mucolipin 3 0.0051 0.0067 0.0067
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Schistosoma mansoni cathepsin F (C01 family) 0.1039 0.2001 0.292
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0803 0.154 0.2247
Trichomonas vaginalis chromobox protein, putative 0.0042 0.005 0.0157
Entamoeba histolytica cysteine protease, putative 0.1503 0.291 1
Loa Loa (eye worm) Smad1 0.0025 0.0018 0.0025
Schistosoma mansoni biogenic amine receptor 0.0083 0.013 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0357 0.0667 0.2281
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0063 0.0092 0.0134
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0088 0.0141 0.014
Echinococcus multilocularis prefoldin subunit 6 0.0066 0.0098 0.0097
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0029
Giardia lamblia Sirtuin type 2 0.0032 0.003 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0338 0.063 0.1708
Leishmania major hypothetical protein, conserved 0.0232 0.0421 0.1138
Plasmodium falciparum metacaspase-like protein 0.0044 0.0053 0.0179
Trypanosoma brucei hypothetical protein, conserved 0.0151 0.0265 0.071
Leishmania major calcium channel protein, putative,ion transporter, putative 0.004 0.0047 0.0115
Brugia malayi Proteasome A-type and B-type family protein 0.0146 0.0254 0.0365
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0357 0.0667 0.2292
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0035 0.0045
Onchocerca volvulus 0.0031 0.0029 0.0084
Entamoeba histolytica cysteine protease, putative 0.0357 0.0667 0.2281
Toxoplasma gondii exonuclease III APE 0.0018 0.0004 0.001
Echinococcus multilocularis serotonin receptor 0.0083 0.013 0.013
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0357 0.0667 0.0973
Giardia lamblia Hypothetical protein 0.0357 0.0667 0.2582
Schistosoma mansoni cpg binding protein 0.0086 0.0136 0.0198
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0136 0.0198
Onchocerca volvulus 0.0031 0.0029 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi Muscle positioning protein 4 0.0019 0.0005 0.0001
Trypanosoma brucei conserved protein 0.0241 0.0441 0.1191
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Echinococcus multilocularis cathepsin L 0.0822 0.1576 0.1576
Brugia malayi MH2 domain containing protein 0.0025 0.0018 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Onchocerca volvulus 0.1503 0.291 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0028
Brugia malayi glutathione reductase 0.0104 0.0172 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.001 0.0009
Trypanosoma brucei DNA polymerase eta, putative 0.005 0.0067 0.017
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0066 0.0098 0.0337
Echinococcus multilocularis orexin receptor type 2 0.0083 0.013 0.013
Brugia malayi KE2 family protein 0.0066 0.0098 0.0136
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0146 0.0254 0.0365
Echinococcus multilocularis cathepsin L cysteine protease 0.1503 0.291 0.291
Trypanosoma brucei protein I/6 0.0151 0.0265 0.071
Schistosoma mansoni Mername-AA248 (C02 family) 0.0974 0.1875 0.2736
Loa Loa (eye worm) hypothetical protein 0.0357 0.0667 0.0973
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.001 0.0009
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0357 0.0667 0.0968
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0083 0.013 0.019
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0018 0.0025
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.003 0.009
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Toxoplasma gondii proteasome subunit beta type, putative 0.0146 0.0254 0.087
Trypanosoma brucei unspecified product 0.0232 0.0421 0.1138
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0357 0.0667 0.2292
Trichomonas vaginalis centrin, putative 0.0028 0.0024 0.0066
Onchocerca volvulus 0.0041 0.0048 0.015
Brugia malayi TAR-binding protein 0.0067 0.0099 0.0138
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0974 0.1875 0.2732
Toxoplasma gondii microneme protein MIC17A 0.0031 0.0029 0.0095
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0293 0.0542 0.1468
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Plasmodium vivax hypothetical protein, conserved 0.0032 0.003 0.0104
Echinococcus multilocularis dro:myosuppressin receptor 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0087 0.0139 0.0203
Loa Loa (eye worm) programmed cell death protein 6 0.0155 0.0272 0.0397
Onchocerca volvulus 0.0083 0.013 0.0432
Trypanosoma cruzi cysteine peptidase, putative 0.1891 0.3669 0.5353
Plasmodium vivax serine-repeat antigen (SERA) 0.0357 0.0667 0.2292
Entamoeba histolytica calcium binding family protein 0.0151 0.0265 0.0896
Toxoplasma gondii cathepsin B 0.1334 0.2579 0.8864
Toxoplasma gondii subtilisin SUB12 0.0031 0.0029 0.0095
Loa Loa (eye worm) acetyltransferase 0.0143 0.0247 0.0361
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1009 0.1942 0.283
Leishmania major hypothetical protein, conserved 0.0232 0.0421 0.1138
Echinococcus granulosus neurogenic locus notch protein 0.0019 0.0005 0.0004
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0265 0.0386
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Plasmodium vivax proteasome subunit beta type-5, putative 0.0146 0.0254 0.0874
Onchocerca volvulus 0.004 0.0047 0.0147
Schistosoma mansoni amine GPCR 0.0083 0.013 0.019
Echinococcus multilocularis thyroid hormone receptor alpha 0.0163 0.0287 0.0287
Plasmodium falciparum proteasome subunit beta type-5 0.0146 0.0254 0.087
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0047 0.0898
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0357 0.0667 0.2281
Echinococcus granulosus serotonin receptor 0.0083 0.013 0.013
Giardia lamblia Hypothetical protein 0.0066 0.0098 0.0374
Onchocerca volvulus 0.0088 0.014 0.0465
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Onchocerca volvulus 0.0034 0.0036 0.0106
Plasmodium falciparum cysteine proteinase falcipain 3 0.1503 0.291 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.004 0.0047 0.0046
Echinococcus granulosus lamin dm0 0.0059 0.0083 0.0082
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0039 0.0146
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.003 0.01
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0123 0.021 0.0708
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0357 0.0667 0.0973
Toxoplasma gondii aspartyl protease 0.0051 0.0069 0.0231
Leishmania major kinesin, putative 0.0576 0.1096 0.2979
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Schistosoma mansoni neuropeptide receptor 0.0083 0.013 0.019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0044 0.0064
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0232 0.0421 0.1138
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0629 0.12 0.1746
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0099 0.0144
Toxoplasma gondii EF hand domain-containing protein 0.0028 0.0024 0.0076
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0033 0.0077
Echinococcus multilocularis somatostatin receptor 0.0083 0.013 0.013
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0047 0.1726
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0018 0.0025
Echinococcus granulosus caspase 2 0.0084 0.0133 0.0133
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0047 0.0063
Leishmania major calpain protease-like protein 0.0398 0.0747 0.2026
Leishmania major cathepsin L-like protease 0.1503 0.291 0.7928
Trypanosoma cruzi metacaspase, putative 0.0044 0.0053 0.0072
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0026 0.0084
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0063 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Plasmodium falciparum plasmepsin III 0.0051 0.0069 0.0231
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.001 0.001
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0028 0.0024 0.0065
Brugia malayi Cathepsin L-like precursor 0.1503 0.291 0.4244
Onchocerca volvulus 0.0031 0.0029 0.0084
Loa Loa (eye worm) calpain 0.0974 0.1875 0.2736
Schistosoma mansoni opsin-like receptor 0.0083 0.013 0.019
Echinococcus multilocularis g protein coupled receptor 0.0083 0.013 0.013
Echinococcus multilocularis caspase 3 0.0071 0.0107 0.0107
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0238 0.0433 0.8921
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0053 0.0169
Echinococcus granulosus FTZ F1 alpha 0.0021 0.001 0.001
Brugia malayi Cathepsin L-like precursor 0.1503 0.291 0.4244
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0974 0.1875 0.2732
Leishmania major calmodulin, putative 0.0151 0.0265 0.071
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.003 0.009
Trypanosoma brucei antigen, putative 0.0974 0.1875 0.5103
Plasmodium falciparum pyruvate kinase 0.0033 0.0033 0.0108
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0357 0.0667 0.0973
Trichomonas vaginalis conserved hypothetical protein 0.0375 0.0702 0.2402
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.003 0.01
Echinococcus multilocularis neuropeptide receptor 0.0083 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0058 0.0082 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.001 0.0014
Trypanosoma brucei prefoldin subunit, putative 0.0066 0.0098 0.0255
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2385 0.4634 0.4634
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1268 0.2449 0.3571
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1503 0.291 1
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0053 0.0184
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.096 0.1847 0.5028
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0265 0.0386
Brugia malayi RE15519p 0.0083 0.013 0.0184
Echinococcus granulosus EF HAND 1 calcium binding site 0.0151 0.0265 0.0264
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Trypanosoma cruzi metacaspase, putative 0.0044 0.0053 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.013 0.013
Onchocerca volvulus 0.0083 0.013 0.0432
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.001 0.0014
Trypanosoma cruzi calmodulin, putative 0.0151 0.0265 0.038
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0053 0.0179
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.001 0.0014
Echinococcus multilocularis calpain 7 (C02 family) 0.0974 0.1875 0.1874
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0267 0.0267
Loa Loa (eye worm) RecQ helicase 0.0024 0.0015 0.0022
Brugia malayi programmed cell death protein 6 0.0151 0.0265 0.038
Schistosoma mansoni smad 0.0025 0.0018 0.0025
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0005 0.0007
Brugia malayi Muscleblind-like protein 0.0153 0.0267 0.0384
Schistosoma mansoni chromatin regulatory protein sir2 0.0123 0.021 0.0306
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0039 0.005
Schistosoma mansoni mucolipin 0.0051 0.0067 0.0098
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Echinococcus granulosus calpain 0.0974 0.1875 0.1874
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.0247 0.0355
Loa Loa (eye worm) Notch2 0.0019 0.0005 0.0006
Giardia lamblia DINP protein human, muc B family 0.0022 0.0011 0.0036
Trichomonas vaginalis calmodulin, putative 0.018 0.032 0.1086
Toxoplasma gondii calcium binding egf domain-containing protein 0.0029 0.0026 0.0084
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0357 0.0667 0.0973
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0015 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Giardia lamblia Cathepsin B precursor 0.0357 0.0667 0.2582
Onchocerca volvulus 0.0031 0.0029 0.0084
Brugia malayi Matrixin family protein 0.0024 0.0016 0.0017
Schistosoma mansoni alpha-1 adrenergic receptor 0.0083 0.013 0.019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0024 0.0023
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0015 0.0016
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0024 0.0034
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.001 0.0009
Echinococcus granulosus smad 0.0025 0.0018 0.0017
Brugia malayi hypothetical protein 0.0249 0.0455 0.0658
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0011 0.0133
Brugia malayi Calcium binding EGF domain containing protein 0.0019 0.0005 0.0001
Echinococcus granulosus calumenin 0.0155 0.0272 0.0272
Echinococcus multilocularis musashi 0.0059 0.0083 0.0082
Schistosoma mansoni biogenic amine receptor 0.0083 0.013 0.019
Giardia lamblia Hypothetical protein 0.0357 0.0667 0.2582
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0033 0.0145
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0123 0.021 0.021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.079 0.1515 0.2206
Brugia malayi RNA binding protein 0.0067 0.0099 0.0138
Trypanosoma brucei cysteine peptidase C (CPC) 0.1334 0.2579 0.7026
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0398 0.0747 0.2555
Brugia malayi MH2 domain containing protein 0.037 0.0693 0.1006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0353 0.0352
Mycobacterium ulcerans hypothetical protein 0.0088 0.014 0.5418
Echinococcus multilocularis G-protein coupled receptor, putative 0.0083 0.013 0.013
Echinococcus granulosus cpg binding protein 0.0091 0.0146 0.0145
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0083 0.013 0.0184
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Loa Loa (eye worm) cathepsin B 0.1334 0.2579 0.3765
Leishmania major phospholipase c-like protein 0.0151 0.0265 0.071
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0053 0.0169
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0974 0.1875 0.2732
Leishmania major metacaspase, putative 0.0044 0.0053 0.0134
Echinococcus multilocularis chromobox protein 1 0.0069 0.0104 0.0103
Echinococcus multilocularis G protein coupled receptor 139 0.0083 0.013 0.013
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3517 0.685 1
Echinococcus granulosus dna polymerase kappa 0.0022 0.0011 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0357 0.0667 0.2281
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0042
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0357 0.0667 0.2292
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Schistosoma mansoni coup transcription factor 0.0021 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Schistosoma mansoni centrin-related 0.0151 0.0265 0.0386
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0047
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0024 0.0034
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Brugia malayi Cathepsin L-like precursor 0.1503 0.291 0.4244
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.013 0.013
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0155 0.0272 0.0392
Echinococcus granulosus chromobox protein 1 0.0069 0.0104 0.0103
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0033 0.0096
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0053 0.0077
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Loa Loa (eye worm) sirtuin 4 0.0032 0.003 0.0044
Loa Loa (eye worm) calmodulin-like protein 0.0151 0.0265 0.0386
Onchocerca volvulus 0.0083 0.013 0.0432
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0004 0.0004
Trypanosoma brucei Metacaspase-4 0.0044 0.0053 0.0134
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0357 0.0667 0.2289
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0022
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0039 0.0119
Onchocerca volvulus 0.0059 0.0083 0.0269
Brugia malayi MH1 domain containing protein 0.0025 0.0018 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Onchocerca volvulus 0.0155 0.0272 0.0921
Schistosoma mansoni hypothetical protein 0.0083 0.013 0.019
Brugia malayi NAD-dependent deacetylase SIRT1 0.0137 0.0236 0.0338
Loa Loa (eye worm) hypothetical protein 0.0249 0.0455 0.0663
Loa Loa (eye worm) AStacin protease 0.0057 0.008 0.0116
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1268 0.2449 0.667
Brugia malayi Papain family cysteine protease containing protein 0.0357 0.0667 0.0968
Trypanosoma brucei unspecified product 0.0022 0.0011 0.0017
Trichomonas vaginalis chromobox protein, putative 0.0042 0.005 0.0157
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trichomonas vaginalis caltractin, putative 0.0028 0.0024 0.0066
Loa Loa (eye worm) blistered cuticle protein 3 0.016 0.0281 0.0409
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0974 0.1875 0.5103
Echinococcus multilocularis transmembrane protease serine 3 0.0088 0.014 0.0139
Onchocerca volvulus 0.0088 0.014 0.0465
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0035 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0196 0.0353 0.0514
Loa Loa (eye worm) hypothetical protein 0.0044 0.0053 0.0077
Leishmania major hypothetical protein, conserved 0.0232 0.0421 0.1138
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0083 0.013 0.019
Echinococcus granulosus cathepsin l cysteine peptidase 0.1503 0.291 0.291
Echinococcus granulosus centrin 2 0.0151 0.0265 0.0264
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0042
Trypanosoma brucei small myristoylated protein 1-1 0.0399 0.075 0.2034
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0232 0.0421 0.1138
Giardia lamblia Cathepsin L precursor 0.0357 0.0667 0.2582
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.013 0.013
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.001 0.0009
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.003 0.0026 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0028 0.0083
Brugia malayi Peroxidasin 0.016 0.0281 0.0404
Trypanosoma brucei metacaspase MCA3 0.0044 0.0053 0.0134
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0011 0.0015
Mycobacterium tuberculosis Conserved protein 0.004 0.0047 0.0898
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Schistosoma mansoni amine GPCR 0.0083 0.013 0.019
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0025 0.0025
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0083 0.013 0.0184
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0151 0.0265 0.0896
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.013 0.013
Echinococcus granulosus dnaJ subfamily B 0.0803 0.154 0.1539
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0146 0.0254 0.086
Trypanosoma cruzi cysteine proteinase, putative 0.0822 0.1576 0.2296
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0019
Brugia malayi hypothetical protein 0.016 0.0281 0.0404
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0006
Trypanosoma cruzi major cysteine proteinase, putative 0.0357 0.0667 0.0968
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0037
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0091 0.0147 0.0214
Onchocerca volvulus Peroxidasin homolog 0.016 0.0281 0.095
Brugia malayi Matrixin family protein 0.0024 0.0016 0.0017
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Echinococcus multilocularis calpain 0.0974 0.1875 0.1874
Trypanosoma brucei calpain-like protein, putative 0.0974 0.1875 0.5103
Echinococcus multilocularis programmed cell death protein 0.018 0.032 0.0319
Brugia malayi intermediate filament protein 0.0059 0.0083 0.0115
Trypanosoma cruzi cysteine protease, putative 0.0822 0.1576 0.2296
Schistosoma mansoni hypothetical protein 0.0083 0.013 0.019
Echinococcus granulosus microtubule associated protein 2 0.0681 0.1301 0.1301
Echinococcus multilocularis caspase 0.0115 0.0193 0.0192
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0039 0.005
Treponema pallidum NADH oxidase 0.0036 0.0039 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.003 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0609 0.1161 0.3155
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Trypanosoma brucei mitochondrial calcium uptake 1 0.0151 0.0265 0.071
Loa Loa (eye worm) hypothetical protein 0.0465 0.0878 0.128
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0151 0.0265 0.038
Schistosoma mansoni cathepsin S (C01 family) 0.0357 0.0667 0.0973
Schistosoma mansoni reticulocalbin 0.0155 0.0272 0.0397
Loa Loa (eye worm) proteasome subunit beta type 1 0.0063 0.0092 0.0134
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0232 0.0421 0.0609
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.013 0.019
Loa Loa (eye worm) hypothetical protein 0.0153 0.0267 0.039
Schistosoma mansoni hypothetical protein 0.0068 0.0101 0.0146
Toxoplasma gondii centrin family protein 0.0028 0.0024 0.0076
Brugia malayi larval opioid receptor 0.0083 0.013 0.0184
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0009
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0974 0.1875 0.2732
Leishmania major calmodulin-like protein 0.0151 0.0265 0.071
Entamoeba histolytica cysteine proteinase, putative 0.0822 0.1576 0.541
Giardia lamblia Cathepsin B precursor 0.1334 0.2579 1
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0101 0.0141
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0088 0.014 0.0139
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0051 0.0069 0.0099
Brugia malayi Tachykinin-like peptides receptor 99D 0.0083 0.013 0.0184
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0033 0.1136
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0098 0.0322
Echinococcus granulosus pyruvate kinase 0.0033 0.0033 0.0032
Onchocerca volvulus 0.0079 0.0123 0.0409
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0088 0.014 0.0139
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.001 0.001
Onchocerca volvulus Peroxidase homolog 0.016 0.0281 0.095
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0033 0.0041
Echinococcus granulosus chromobox protein 1 0.0069 0.0104 0.0103
Toxoplasma gondii PAN domain-containing protein 0.0031 0.0029 0.0095
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0155 0.0226
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.013 0.013
Echinococcus granulosus cathepsin b 0.3517 0.685 0.685
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.0667 0.0973
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.003 0.009
Loa Loa (eye worm) calpain D 0.0398 0.0747 0.109
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0894 0.1718 0.4675
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.0101 0.0101
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.001 0.001
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0033 0.0591
Echinococcus granulosus 7tm_1 domain containing protein 0.0083 0.013 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0101 0.0147
Echinococcus granulosus allatostatin A receptor 0.0083 0.013 0.013
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0259 0.0474 0.9776
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0196 0.0353 0.0509
Leishmania major cysteine peptidase A (CPA) 0.1503 0.291 0.7928
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0398 0.0747 0.2555
Leishmania major cathepsin L-like protease 0.1891 0.3669 1
Toxoplasma gondii PAN/Apple domain-containing protein 0.0031 0.0029 0.0095
Onchocerca volvulus 0.0088 0.014 0.0465
Onchocerca volvulus 0.004 0.0047 0.0147
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0069
Trypanosoma brucei calpain, putative 0.0398 0.0747 0.2026
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0242 0.0441 0.0643
Echinococcus multilocularis cathepsin b 0.3517 0.685 0.685
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.003 0.01
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0063 0.0092 0.024
Schistosoma mansoni biogenic amine (5HT) receptor 0.0083 0.013 0.019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0079 0.0123 0.018
Trypanosoma brucei Calpain-like protein 1.1 0.1009 0.1942 0.5287
Schistosoma mansoni mitochondrial solute carrier 0.0151 0.0265 0.0386
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0063 0.0092 0.0302
Plasmodium falciparum plasmepsin X 0.0051 0.0069 0.0231
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.024 0.0239
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0293 0.0542 0.1468
Brugia malayi fibroinase precursor 0.0357 0.0667 0.0968
Toxoplasma gondii calcium binding protein precursor, putative 0.0028 0.0024 0.0076
Echinococcus multilocularis smad 0.0025 0.0018 0.0017
Schistosoma mansoni opsin-like receptor 0.0083 0.013 0.019
Loa Loa (eye worm) animal heme peroxidase 0.016 0.0281 0.0409
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.001 0.0014
Onchocerca volvulus 0.0083 0.013 0.0432
Onchocerca volvulus 0.0066 0.0098 0.0322
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0037 0.0053
Schistosoma mansoni ap endonuclease 0.0018 0.0004 0.0006
Brugia malayi Matrixin family protein 0.0024 0.0016 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0357 0.0667 0.2281
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Onchocerca volvulus 0.0086 0.0136 0.0453
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0034
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0146 0.0254 0.086
Onchocerca volvulus 0.0031 0.0029 0.0084
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0099 0.0138
Plasmodium vivax prefoldin subunit 6, putative 0.0066 0.0098 0.0336
Loa Loa (eye worm) transcriptional regulator 0.0123 0.021 0.0306
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0004 0.001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.005 0.0169
Plasmodium falciparum glutathione reductase 0.0036 0.0039 0.0129
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0015 0.0014
Echinococcus multilocularis cathepsin L cysteine protease 0.1503 0.291 0.291
Brugia malayi RasGEF domain containing protein 0.0028 0.0024 0.0028
Mycobacterium tuberculosis Probable oxidoreductase 0.0264 0.0485 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0822 0.1576 0.2301
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0088 0.014 0.0203
Echinococcus multilocularis cathepsin b 0.3517 0.685 0.685
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Echinococcus granulosus muscleblind protein 0.0153 0.0267 0.0267
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0357 0.0667 0.2582
Entamoeba histolytica calcium-binding protein, putative 0.0151 0.0265 0.0896
Leishmania major i/6 autoantigen-like protein 0.0151 0.0265 0.071
Leishmania major DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Brugia malayi Fibulin-1 precursor 0.0029 0.0026 0.0031
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Loa Loa (eye worm) hypothetical protein 0.0162 0.0286 0.0417
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1942 0.283
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.013 0.019
Schistosoma mansoni intermediate filament proteins 0.0059 0.0083 0.012
Brugia malayi Eukaryotic aspartyl protease family protein 0.0051 0.0069 0.0094
Onchocerca volvulus Peroxidasin homolog 0.016 0.0281 0.095
Loa Loa (eye worm) hypothetical protein 0.0158 0.0278 0.0405
Brugia malayi Serotonin receptor 0.0083 0.013 0.0184
Trypanosoma cruzi cysteine peptidase, putative 0.1503 0.291 0.4244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1268 0.2449 0.667
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0151 0.0265 0.0909
Leishmania major centrin, putative 0.0151 0.0265 0.071
Brugia malayi Dopamine receptor 0.0083 0.013 0.0184
Entamoeba histolytica grainin 2 0.0028 0.0024 0.0066
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0083 0.013 0.019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0011 0.0009
Echinococcus multilocularis peroxidasin 0.016 0.0281 0.028
Leishmania major hypothetical protein, conserved 0.0151 0.0265 0.071
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.003 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0061
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0039 0.0038
Giardia lamblia Cathepsin L precursor 0.0357 0.0667 0.2582
Trichomonas vaginalis calcium binding protein, putative 0.0151 0.0265 0.0896
Giardia lamblia Pyruvate kinase 0.0033 0.0033 0.0122
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0151 0.0265 0.0386
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Toxoplasma gondii microneme protein MIC17B 0.0031 0.0029 0.0095
Leishmania major pyruvate kinase 0.0033 0.0033 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1186 0.2289 0.6233
Trichomonas vaginalis caltractin, putative 0.0028 0.0024 0.0066
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Onchocerca volvulus 0.016 0.0281 0.095
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1268 0.2449 0.3571
Brugia malayi MH1 domain containing protein 0.0025 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.3517 0.685 1
Echinococcus granulosus tar DNA binding protein 0.0067 0.0099 0.0099
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.005 0.0159
Plasmodium vivax vivapain-1 0.0822 0.1576 0.5417
Toxoplasma gondii EFHC1, putative 0.0151 0.0265 0.0905
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0293 0.0542 0.1468
Loa Loa (eye worm) hypothetical protein 0.1039 0.2001 0.292
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1427 0.276 0.4025
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.003 0.0043
Mycobacterium tuberculosis Probable reductase 0.0238 0.0433 0.8921
Loa Loa (eye worm) hypothetical protein 0.0068 0.0101 0.0146
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0047 0.0898
Leishmania major cathepsin L-like protease 0.1503 0.291 0.7928
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.004
Brugia malayi Trypsin family protein 0.0088 0.014 0.0198
Giardia lamblia Cathepsin B precursor 0.0357 0.0667 0.2582
Echinococcus multilocularis Myosin regulatory light chain 0.0028 0.0024 0.0023
Plasmodium falciparum plasmepsin IV 0.0162 0.0286 0.0978
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0357 0.0667 0.2281
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.013 0.013
Echinococcus multilocularis thioredoxin glutathione reductase 0.0104 0.0172 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Brugia malayi Trypsin family protein 0.0088 0.014 0.0198
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Schistosoma mansoni opsin-like receptor 0.0083 0.013 0.019
Brugia malayi G-protein coupled receptor 0.0083 0.013 0.0184
Trichomonas vaginalis calpain, putative 0.0398 0.0747 0.2555
Leishmania major cathepsin L-like protease 0.1891 0.3669 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0039 0.1383
Trypanosoma cruzi trypanothione reductase, putative 0.0104 0.0172 0.0245
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0035 0.0084
Echinococcus granulosus histone lysine methyltransferase setb 0.0068 0.0101 0.0101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Onchocerca volvulus Cathepsin L homolog 0.0357 0.0667 0.228
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Echinococcus granulosus tissue type plasminogen activator 0.0066 0.0098 0.0098
Onchocerca volvulus 0.016 0.0281 0.095
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0151 0.0265 0.038
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0463 0.0874 0.1275
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0353 0.0514
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0123 0.021 0.0708
Loa Loa (eye worm) mucolipin 1 0.0051 0.0067 0.0098
Brugia malayi ORL1-like opioid receptor 0.0083 0.013 0.0184
Schistosoma mansoni hypothetical protein 0.0083 0.013 0.019
Loa Loa (eye worm) myosin regulatory light chain 1 0.0028 0.0024 0.0034
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0141 0.0245 0.0245
Trypanosoma cruzi caltractin, putative 0.0151 0.0265 0.038
Echinococcus multilocularis laminin 0.0029 0.0026 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Loa Loa (eye worm) hypothetical protein 0.0099 0.0162 0.0236
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0006
Onchocerca volvulus 0.1259 0.2432 0.8354
Echinococcus multilocularis calcyphosin protein 0.0028 0.0024 0.0023
Echinococcus granulosus calpain A 0.0974 0.1875 0.1874
Loa Loa (eye worm) beta-lactamase 0.004 0.0047 0.0069
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.003 0.0104
Brugia malayi Melatonin receptor type 1A 0.0083 0.013 0.0184
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.013 0.019
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0098 0.0137
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0242 0.0441 0.0441
Schistosoma mansoni myosin light chain 0.0028 0.0024 0.0034
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0137 0.0236 0.0235
Brugia malayi Coelomocyte uptake defective protein 5 0.0051 0.0067 0.0092
Trypanosoma brucei calpain-like protein, putative 0.1268 0.2449 0.667
Echinococcus granulosus geminin 0.0861 0.1653 0.1653
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0073 0.0245
Brugia malayi CXXC zinc finger family protein 0.0086 0.0136 0.0193
Trypanosoma cruzi small myristoylated protein 1-2 0.0399 0.075 0.1089
Brugia malayi ecdysteroid receptor 0.0021 0.001 0.0009
Brugia malayi Cathepsin L-like precursor 0.1503 0.291 0.4244
Echinococcus multilocularis mucolipin 3 0.0051 0.0067 0.0067
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Entamoeba histolytica calpain family cysteine protease, putative 0.0398 0.0747 0.2555
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Trypanosoma brucei calmodulin, putative 0.0155 0.0272 0.0731
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0007
Echinococcus multilocularis geminin 0.0861 0.1653 0.1653
Loa Loa (eye worm) glutathione reductase 0.0104 0.0172 0.0251
Leishmania major centrin, putative 0.0151 0.0265 0.071
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0083 0.013 0.013
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0151 0.0265 0.071
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0357 0.0667 0.2292
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.013 0.013
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.0094
Onchocerca volvulus Neuropeptide F receptor homolog 0.0083 0.013 0.0432
Schistosoma mansoni cathepsin D (A01 family) 0.0446 0.084 0.1226
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0123 0.021 0.0708
Loa Loa (eye worm) cysteine protease 0.1503 0.291 0.4247
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0083 0.013 0.0432
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.003 0.0038
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0063 0.0092 0.0312
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0088 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Onchocerca volvulus 0.0158 0.0278 0.094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3517 0.685 1
Toxoplasma gondii calcium-dependent protein kinase 0.0155 0.0272 0.0932
Brugia malayi Calcium binding EGF domain containing protein 0.0029 0.0026 0.0031
Trypanosoma brucei calpain-like protein, putative 0.0974 0.1875 0.5103
Echinococcus granulosus g-protein coupled receptor 0.0083 0.013 0.013
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.005 0.0169
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0047 0.0148
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0162 0.023
Loa Loa (eye worm) hypothetical protein 0.0137 0.0236 0.0343
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Loa Loa (eye worm) hypothetical protein 0.0242 0.0441 0.0643
Schistosoma mansoni amine GPCR 0.0083 0.013 0.019
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Loa Loa (eye worm) animal heme peroxidase 0.016 0.0281 0.0409
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0039 0.0094
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Plasmodium falciparum serine repeat antigen 1 0.0357 0.0667 0.2289
Brugia malayi calpain D 0.0398 0.0747 0.1085
Echinococcus granulosus orexin receptor type 2 0.0083 0.013 0.013
Schistosoma mansoni cathepsin D (A01 family) 0.0446 0.084 0.1226
Schistosoma mansoni cathepsin B (C01 family) 0.0357 0.0667 0.0973
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0039 0.0056
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.001 0.0014
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.003 0.0071
Loa Loa (eye worm) hypothetical protein 0.1039 0.2001 0.292
Trypanosoma cruzi centrin-3 0.018 0.032 0.0461
Entamoeba histolytica calmodulin, putative 0.0151 0.0265 0.0896
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Brugia malayi G-protein coupled receptor 0.0083 0.013 0.0184
Echinococcus multilocularis neuropeptide receptor A26 0.0417 0.0785 0.0785
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0042
Trypanosoma brucei metacaspase MCA2 0.0044 0.0053 0.0134
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.001 0.0009
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0018 0.0017
Onchocerca volvulus Matrilysin homolog 0.0024 0.0016 0.0038
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.005 0.005
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Brugia malayi neuropeptide F receptor 0.0083 0.013 0.0184
Brugia malayi Trypsin-like protease protein 5 0.0088 0.014 0.0198
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.0329 0.048
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0039 0.0129
Onchocerca volvulus 0.0059 0.0083 0.0269
Plasmodium falciparum centrin-4 0.0028 0.0024 0.0076
Leishmania major cathepsin L-like protease 0.1503 0.291 0.7928
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1039 0.2001 0.6871
Toxoplasma gondii microneme protein, putative 0.0031 0.0029 0.0095
Onchocerca volvulus 0.0083 0.013 0.0432
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.001 0.001
Brugia malayi hypothetical protein 0.0088 0.014 0.0198
Brugia malayi Protein kinase domain containing protein 0.0066 0.0098 0.0137
Loa Loa (eye worm) hypothetical protein 0.1039 0.2001 0.292
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0011 0.0015
Giardia lamblia Cathepsin B precursor 0.1334 0.2579 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0039 0.0094
Plasmodium falciparum plasmepsin I 0.0162 0.0286 0.0978
Echinococcus granulosus sex peptide receptor 0.0083 0.013 0.013
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.002 0.0023
Giardia lamblia Cathepsin L precursor 0.0357 0.0667 0.2582
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.003 0.0038
Entamoeba histolytica calmodulin, putative 0.0028 0.0024 0.0066
Loa Loa (eye worm) hypothetical protein 0.1259 0.2432 0.3549
Leishmania major trypanothione reductase 0.0104 0.0172 0.0458
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0013 0.0019
Onchocerca volvulus Chorion peroxidase homolog 0.016 0.0281 0.095
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.001 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0011 0.0022
Brugia malayi Dopamine receptor protein 1 0.0083 0.013 0.0184
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0104 0.0172 0.349
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0044 0.0136
Plasmodium falciparum plasmepsin IX 0.0051 0.0069 0.0231
Echinococcus multilocularis g protein coupled receptor 0.0083 0.013 0.013
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0083 0.013 0.013
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Trichomonas vaginalis calcineurin B subunit, putative 0.0151 0.0265 0.0896
Trichomonas vaginalis centrin, putative 0.0028 0.0024 0.0066
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0039 0.0129
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Entamoeba histolytica cysteine protease, putative 0.0357 0.0667 0.2281
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0068 0.0101 0.0101
Schistosoma mansoni caspase-3 (C14 family) 0.0115 0.0193 0.0281
Brugia malayi cathepsin Z-like cysteine proteinase 0.0357 0.0667 0.0968
Schistosoma mansoni hypothetical protein 0.0066 0.0098 0.0142
Echinococcus multilocularis calmodulin 0.0151 0.0265 0.0264
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0004 0.0015
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0465 0.0878 0.128
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Echinococcus granulosus intermediate filament protein 0.0059 0.0083 0.0082
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1503 0.291 1
Trypanosoma cruzi prefoldin subunit, putative 0.0066 0.0098 0.0136
Brugia malayi cathepsin B-like cysteine proteinase 0.3517 0.685 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0357 0.0667 0.2582
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0137 0.0236 0.0796
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0754 0.1444 0.2104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0006
Plasmodium vivax vivapain-2 0.1503 0.291 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.001 0.0014
Echinococcus multilocularis chromatin regulatory protein sir2 0.0123 0.021 0.0209
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0083 0.013 0.013
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0357 0.0667 0.2582
Echinococcus multilocularis pyruvate kinase 0.0026 0.0019 0.0019
Echinococcus multilocularis pyruvate kinase 0.0017 0.0001 0.0001
Schistosoma mansoni peptidylglycine monooxygenase 0.0128 0.0219 0.032
Echinococcus multilocularis proteasome (prosome, macropain) 0.0146 0.0254 0.0254
Onchocerca volvulus Peroxidase homolog 0.016 0.0281 0.095
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.005
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0033 0.0041
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.001 0.0014
Echinococcus multilocularis neurocalcin 0.0151 0.0265 0.0264
Echinococcus granulosus laminin 0.0029 0.0026 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0375 0.0702 0.1019
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0398 0.0747 0.2555
Trichomonas vaginalis calmodulin, putative 0.0155 0.0272 0.0923
Echinococcus multilocularis Mastin 0.0088 0.014 0.0139
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0063 0.0092 0.0128
Schistosoma mansoni cercarial elastase (S01 family) 0.0088 0.014 0.0203
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0232 0.0421 0.1138
Brugia malayi beta-lactamase 0.004 0.0047 0.0063
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0011 0.0133
Entamoeba histolytica cysteine proteinase, putative 0.0822 0.1576 0.541
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0629 0.12 0.1746
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0083 0.013 0.013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0609 0.1161 0.1689
Trypanosoma brucei centrin-3 0.018 0.032 0.0861
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0047 0.0047
Entamoeba histolytica cysteine protease, putative 0.0357 0.0667 0.2281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0053 0.0072
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0033 0.0047
Brugia malayi Trypsin family protein 0.0088 0.014 0.0198
Schistosoma mansoni reticulocalbin 0.0151 0.0265 0.0386
Echinococcus granulosus proteasome prosome macropain 0.0146 0.0254 0.0254
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0047 0.0063
Brugia malayi Papain family cysteine protease containing protein 0.0357 0.0667 0.0968
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.0031 0.0045
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0115 0.0193 0.0192
Brugia malayi hypothetical protein 0.0051 0.0069 0.0094
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0039 1
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0053 0.0169
Plasmodium falciparum prefoldin subunit 6, putative 0.0066 0.0098 0.0331
Trichomonas vaginalis calcium binding proteins, putative 0.0151 0.0265 0.0896
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0015 0.0014
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0039 1
Toxoplasma gondii cathepsin CPC2 0.0357 0.0667 0.2289
Onchocerca volvulus 0.0021 0.001 0.0019
Plasmodium vivax proteasome subunit beta type-1, putative 0.0063 0.0092 0.0317
Onchocerca volvulus Cell death protein 3 homolog 0.0084 0.0133 0.0443
Leishmania major DNA polymerase eta, putative 0.005 0.0067 0.017
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1942 0.5287
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0047 0.0069
Brugia malayi Blistered cuticle protein 3 0.016 0.0281 0.0404
Onchocerca volvulus 0.0031 0.0029 0.0084
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1503 0.291 0.291
Loa Loa (eye worm) hypothetical protein 0.004 0.0047 0.0069
Plasmodium vivax calpain, putative 0.0974 0.1875 0.6442
Brugia malayi GnHR receptor homolog 0.0083 0.013 0.0184
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0015 0.0037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.013 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0667 0.2281
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Schistosoma mansoni cathepsin F (C01 family) 0.1503 0.291 0.4247
Plasmodium vivax plasmepsin V, putative 0.0051 0.0069 0.0236
Leishmania major pyruvate kinase 0.0033 0.0033 0.0077
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Trichomonas vaginalis set domain proteins, putative 0.0526 0.0998 0.3421
Schistosoma mansoni hypothetical protein 0.0066 0.0098 0.0143
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0051 0.0069 0.0099
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0088 0.014 0.0203
Echinococcus granulosus calcyphosin protein 0.0028 0.0024 0.0023
Toxoplasma gondii microneme protein MIC17C 0.0031 0.0029 0.0095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.096 0.1847 0.5028
Trichomonas vaginalis myosin light chain 1, putative 0.0151 0.0265 0.0896
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1334 0.2579 0.8863
Schistosoma mansoni mucolipin 0.0046 0.0059 0.0086
Plasmodium falciparum serine repeat antigen 8 0.0357 0.0667 0.2289
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0073 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Plasmodium vivax thioredoxin reductase, putative 0.0104 0.0172 0.0591
Leishmania major hypothetical protein, conserved 0.0232 0.0421 0.1138
Leishmania major calpain family cysteine protease-like protein 0.0629 0.12 0.3262
Echinococcus granulosus EF hand domain containing family member A2 0.0151 0.0265 0.0264
Brugia malayi Calcium binding EGF domain containing protein 0.0019 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0044 0.0137
Plasmodium vivax aspartyl protease, putative 0.0051 0.0069 0.0236
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1503 0.291 1
Onchocerca volvulus 0.0028 0.0024 0.0065
Loa Loa (eye worm) RNA binding protein 0.0067 0.0099 0.0144
Toxoplasma gondii hypothetical protein 0.0031 0.0029 0.0095
Echinococcus granulosus g protein coupled receptor 0.0083 0.013 0.013
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0024 0.0016 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1891 0.3669 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0053 0.0179
Schistosoma mansoni amine GPCR 0.0083 0.013 0.019
Trypanosoma brucei trypanothione reductase 0.0104 0.0172 0.0458
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Brugia malayi PAN domain containing protein 0.0031 0.0029 0.0036
Echinococcus granulosus cathepsin L 0.0822 0.1576 0.1576
Schistosoma mansoni hypothetical protein 0.0151 0.0265 0.0386
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0034
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0083 0.013 0.013
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0162 0.0286 0.0978
Brugia malayi G protein-coupled receptor 0.0083 0.013 0.0184
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Schistosoma mansoni lamin 0.0059 0.0083 0.012
Trichomonas vaginalis calmodulin, putative 0.0151 0.0265 0.0896
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Trypanosoma cruzi small myristoylated protein 1-1 0.0399 0.075 0.1089
Loa Loa (eye worm) myosin Light Chain family member 0.0032 0.0031 0.0045
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0151 0.0265 0.038
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0088 0.014 0.0203
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0004 0.0006
Plasmodium vivax aspartyl protease, putative 0.0051 0.0069 0.0236
Loa Loa (eye worm) notch protein 0.0019 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1503 0.291 1
Trypanosoma cruzi hypothetical protein, conserved 0.0232 0.0421 0.0609
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0011 0.0022
Brugia malayi Cathepsin L-like precursor 0.1039 0.2001 0.2916
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0232 0.0421 0.0609
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2385 0.4634 0.6765
Giardia lamblia Cathepsin B precursor 0.0357 0.0667 0.2582
Schistosoma mansoni microtubule-associated protein tau 0.0681 0.1301 0.1899
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Mycobacterium ulcerans hypothetical protein 0.004 0.0047 0.1726
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0011 0.0256
Echinococcus granulosus dro:myosuppressin receptor 0.0083 0.013 0.013
Onchocerca volvulus 0.0083 0.013 0.0432
Onchocerca volvulus 0.1503 0.291 1
Plasmodium vivax hypothetical protein, conserved 0.004 0.0047 0.0163
Onchocerca volvulus 0.0031 0.0029 0.0084
Echinococcus granulosus neurocalcin 0.0151 0.0265 0.0264
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0146 0.0254 0.0365
Leishmania major hypothetical protein, conserved 0.0232 0.0421 0.1138
Brugia malayi hypothetical protein 0.0083 0.013 0.0184
Echinococcus multilocularis centrin 2 0.0151 0.0265 0.0264
Giardia lamblia Cysteine protease 0.0357 0.0667 0.2582
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0398 0.0747 0.2555
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0141 0.0245 0.0245
Echinococcus granulosus thioredoxin glutathione reductase 0.0104 0.0172 0.0172
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0033 0.0108
Schistosoma mansoni hypothetical protein 0.0041 0.0048 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0357 0.0667 0.2281
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0035 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Plasmodium vivax glutathione reductase, putative 0.0104 0.0172 0.0591
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0238 0.0433 0.887
Schistosoma mansoni calpain C (C02 family) 0.0974 0.1875 0.2736
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.0667 0.0973
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0357 0.0667 0.2582
Schistosoma mansoni peroxidasin 0.016 0.0281 0.0409
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0691 0.1321 0.3593
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0353 0.0352
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0088 0.014 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.005
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0287 0.0418
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.001 0.0014
Plasmodium falciparum plasmepsin VI 0.0162 0.0286 0.0978
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0155 0.0272 0.0397
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0151 0.0265 0.0896
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0123 0.021 0.0561
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0146 0.0254 0.5201
Trypanosoma brucei kinesin, putative 0.0576 0.1096 0.2979
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.003 0.0071
Trypanosoma cruzi kinesin, putative 0.0576 0.1096 0.1595
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0083 0.0115
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0011 0.0017
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.013 0.019
Echinococcus multilocularis calbindin 32 0.0155 0.0272 0.0272
Loa Loa (eye worm) PAN domain-containing protein 0.0031 0.0029 0.0042
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.0093 0.0092
Plasmodium vivax metacaspase 1, putative 0.0044 0.0053 0.0184
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0338 0.063 0.1708
Schistosoma mansoni dopamine-beta-monooxygenase 0.0128 0.0219 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0357 0.0667 0.2289
Toxoplasma gondii preprocathepsin c precursor, putative 0.0357 0.0667 0.2289
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0162 0.023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0022
Entamoeba histolytica calpain large subunit domain III containing protein 0.0576 0.1096 0.3758
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0264 0.0485 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.001 0.0009
Loa Loa (eye worm) calpain family protein 1 0.1657 0.321 0.4686
Echinococcus granulosus GPCR family 2 0.0031 0.003 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.013 0.013
Loa Loa (eye worm) fibroinase 0.1503 0.291 0.4247
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0265 0.0386
Echinococcus granulosus caspase 3 0.0071 0.0107 0.0107
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3517 0.685 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0028 0.0083
Echinococcus granulosus g protein coupled receptor 0.0083 0.013 0.013
Brugia malayi Papain family cysteine protease containing protein 0.1503 0.291 0.4244
Echinococcus multilocularis calmodulin 0.0151 0.0265 0.0264
Echinococcus granulosus glycoprotein Antigen 5 0.0088 0.014 0.0139
Onchocerca volvulus Neurogenic locus notch homolog 0.0019 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0073 0.0105
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1245 0.2405 0.351
Onchocerca volvulus 0.0527 0.0999 0.3422
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Brugia malayi Latrophilin receptor protein 2 0.0031 0.003 0.0037
Loa Loa (eye worm) calpain family protein 1 0.2233 0.4338 0.6332
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0033 0.0112
Trypanosoma cruzi cruzipain precursor, putative 0.0465 0.0878 0.1275
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541
Echinococcus granulosus biogenic amine 5HT receptor 0.0083 0.013 0.013
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0238 0.0433 0.8921
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0629 0.12 0.1746
Toxoplasma gondii histone lysine methyltransferase SET1 0.0169 0.0298 0.102
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0007
Toxoplasma gondii EF hand domain-containing protein 0.0151 0.0265 0.0905
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0037 0.0048
Mycobacterium ulcerans proteasome PrcB 0.0146 0.0254 1
Plasmodium falciparum plasmepsin VIII, putative 0.0051 0.0069 0.0231
Brugia malayi Trypsin family protein 0.0088 0.014 0.0198
Onchocerca volvulus 0.004 0.0047 0.0147
Trypanosoma brucei cysteine peptidase, putative 0.0629 0.12 0.3262
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.003 0.0043
Echinococcus multilocularis neuronal calcium sensor 0.0151 0.0265 0.0264
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0011 0.0017
Giardia lamblia Cysteine protease 0.0357 0.0667 0.2582
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0151 0.0265 0.038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.0009
Echinococcus multilocularis g-protein coupled receptor 0.0083 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0128 0.0219 0.0314
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0104 0.0151
Entamoeba histolytica cysteine protease, putative 0.0357 0.0667 0.2281
Schistosoma mansoni lamin 0.0059 0.0083 0.012
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0083 0.012
Echinococcus multilocularis chromobox protein 1 0.0069 0.0104 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0053 0.0134
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0629 0.12 0.1746
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Echinococcus granulosus lamin 0.0059 0.0083 0.0082
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0357 0.0667 0.2289
Brugia malayi Heterochromatin protein 1 0.0069 0.0104 0.0145
Toxoplasma gondii centrin 0.0151 0.0265 0.0905
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0011 0.0017
Onchocerca volvulus 0.1039 0.2001 0.687
Brugia malayi calpain family protein 1 0.2233 0.4338 0.633
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0151 0.0265 0.0264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1503 0.291 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.013 0.013
Toxoplasma gondii aspartyl protease ASP1 0.0162 0.0286 0.0978
Brugia malayi MH2 domain containing protein 0.0025 0.0018 0.0019
Schistosoma mansoni neuronal calcium sensor 0.0151 0.0265 0.0386
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.003 0.009
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0014
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0151 0.0265 0.0264
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Onchocerca volvulus 0.016 0.0281 0.095
Plasmodium falciparum serine repeat antigen 3 0.0357 0.0667 0.2289
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0242 0.0441 0.0638
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0353 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0024 0.0066
Loa Loa (eye worm) ctsf protein 0.1503 0.291 0.4247
Onchocerca volvulus 0.1503 0.291 1
Trichomonas vaginalis calmodulin-2, putative 0.0151 0.0265 0.0896
Onchocerca volvulus 0.0088 0.014 0.0465
Schistosoma mansoni neuropeptide receptor 0.0083 0.013 0.019
Echinococcus multilocularis calumenin 0.0155 0.0272 0.0272
Brugia malayi Papain family cysteine protease containing protein 0.0822 0.1576 0.2296
Leishmania major cytochrome p450-like protein 0.0034 0.0035 0.0084
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0083 0.013 0.0184
Trypanosoma brucei Component of motile flagella 41 0.0151 0.0265 0.071
Echinococcus granulosus fmrfamide receptor 0.0083 0.013 0.013
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0047 0.0063
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0053 0.0072
Onchocerca volvulus 0.003 0.0028 0.0079
Brugia malayi Cathepsin L-like precursor 0.1039 0.2001 0.2916
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0025 0.0036
Plasmodium vivax vivapain-2 0.1503 0.291 1
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0047 0.0148
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1503 0.291 0.4247
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0011 0.001
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0629 0.12 0.1746
Echinococcus granulosus biogenic amine 5HT receptor 0.0083 0.013 0.013
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0001 0.0005
Brugia malayi Papain family cysteine protease containing protein 0.0357 0.0667 0.0968
Brugia malayi GCC2 and GCC3 family protein 0.0019 0.0005 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0375 0.0702 0.1904
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0011 0.0017
Loa Loa (eye worm) trypsin family protein 0.0088 0.014 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.001 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0028 0.0083
Plasmodium falciparum serine repeat antigen 7 0.0357 0.0667 0.2289
Schistosoma mansoni calpain-2 (C02 family) 0.0398 0.0747 0.109
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.013 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0754 0.1444 0.2104
Loa Loa (eye worm) hypothetical protein 0.0088 0.014 0.0203
Schistosoma mansoni calmodulin related calcium binding protein 0.0151 0.0265 0.0386
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0039 0.0129
Echinococcus multilocularis pyruvate kinase 0.0033 0.0033 0.0032
Loa Loa (eye worm) hypothetical protein 0.0083 0.013 0.019
Trypanosoma brucei Calpain-like protein 1.2 0.079 0.1515 0.4121
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.002 0.0023
Trypanosoma cruzi prefoldin subunit, putative 0.0066 0.0098 0.0136
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0357 0.0667 0.2292
Schistosoma mansoni calpain-7 (C02 family) 0.0974 0.1875 0.2736
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0039 0.005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0039 0.005
Schistosoma mansoni memapsin-2 (A01 family) 0.0454 0.0857 0.125
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0029
Brugia malayi Cathepsin L-like cysteine proteinase 0.1039 0.2001 0.2916
Onchocerca volvulus 0.0083 0.013 0.0432
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0357 0.0667 0.2281
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0047 0.0148
Onchocerca volvulus Cathepsin L homolog 0.1503 0.291 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0123 0.021 0.0708
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.0667 0.0973
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0162 0.0286 0.0417
Plasmodium falciparum plasmepsin VII 0.0051 0.0069 0.0231
Loa Loa (eye worm) hypothetical protein 0.0357 0.0666 0.0972
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.003 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.013 0.019
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0232 0.0421 0.1138
Echinococcus granulosus neuropeptide receptor A26 0.0417 0.0785 0.0785
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.016 0.0281 0.0409
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1942 0.5287
Schistosoma mansoni chromatin regulatory protein sir2 0.0137 0.0236 0.0343
Echinococcus granulosus pyruvate kinase 0.0017 0.0001 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0053 0.0169
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1268 0.2449 0.3571
Leishmania major receptor-type adenylate cyclase a-like protein 0.0232 0.0421 0.1138
Trypanosoma cruzi major cysteine proteinase, putative 0.0745 0.1427 0.2078
Echinococcus multilocularis tissue type plasminogen activator 0.0066 0.0098 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.0667 0.2281
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0051 0.0069 0.01
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0091 0.0147 0.0214
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0011 0.0256
Toxoplasma gondii cathepsin CPC1 0.0357 0.0667 0.2289
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0083 0.013 0.019
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0035 0.1228
Brugia malayi calpain 5 0.0576 0.1096 0.1595
Brugia malayi Dopamine receptor protein 2 0.0083 0.013 0.0184
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0015 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0232 0.0421 0.0609
Leishmania major prefoldin subunit, putative 0.0066 0.0098 0.0255
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0039 1
Trichomonas vaginalis calmodulin, putative 0.0028 0.0024 0.0066
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0146 0.0254 0.0682
Entamoeba histolytica cysteine protease, putative 0.0822 0.1576 0.541

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.115 uM Inhibitory activity against COX2 in canine whole blood ChEMBL. 16275075
IC50 (binding) = 0.115 uM Inhibitory activity against COX2 in canine whole blood ChEMBL. 16275075
IC50 (binding) = 21.5 uM Inhibitory activity against COX1 in canine whole blood ChEMBL. 16275075
IC50 (binding) = 21.5 uM Inhibitory activity against COX1 in canine whole blood ChEMBL. 16275075
Ratio IC50 (binding) = 186.9 Selectivity of COX1 over COX2 in canine whole blood assay ChEMBL. 16275075

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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