Detailed information for compound 48515

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 427.312 | Formula: C9H16N2O5Pt
  • H donors: 2 H acceptors: 1 LogP: -0.37 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CO[Pt]2(O1)NC[C@@H]1[C@H](CN2)OC(O1)(C)C
  • InChi: 1S/C7H14N2O2.C2H3O3.Pt/c1-7(2)10-5(3-8)6(4-9)11-7;3-1-2(4)5;/h5-6,8-9H,3-4H2,1-2H3;1H2,(H,4,5);/q-2;-1;+4/p-1/t5-,6-;;/m1../s1
  • InChiKey: UWFGBEPIRKHWDX-BNTLRKBRSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0057 0.0057 0.0207
Brugia malayi Papain family cysteine protease containing protein 0.0371 0.0632 0.0884
Schistosoma mansoni notch 0.0034 0.0013 0.0019
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0152 0.0212
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0137 0.0204 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.016 0.0246 0.0895
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.0017 0.006
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0049 0.0042 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0225 0.0364 0.0509
Entamoeba histolytica cysteine protease, putative 0.0371 0.0632 0.23
Echinococcus granulosus caspase 8 0.0044 0.0032 0.0032
Trypanosoma cruzi kinesin, putative 0.0631 0.111 0.1553
Echinococcus multilocularis fmrfamide receptor 0.0094 0.0125 0.0125
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0641 0.1128 0.1578
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0036 0.005
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.0412 0.9654
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0108 0.0151 0.0151
Brugia malayi Pepsin A precursor 0.0063 0.0068 0.0095
Leishmania major calmodulin-like protein 0.016 0.0246 0.0662
Plasmodium vivax glutathione reductase, putative 0.0102 0.0139 0.0506
Trypanosoma cruzi unspecified product 0.0387 0.0663 0.0927
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0417 0.0716 0.2608
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0009 0.0012
Loa Loa (eye worm) acetyltransferase 0.0147 0.0221 0.0309
Echinococcus multilocularis Myosin regulatory light chain 0.0028 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0039 0.0024 0.0999
Onchocerca volvulus Putative cubilin 0.0041 0.0027 0.0097
Plasmodium falciparum centrin-1 0.016 0.0246 0.0895
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.012 0.0172 0.0462
Loa Loa (eye worm) hypothetical protein 0.0113 0.0158 0.0222
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Schistosoma mansoni amine GPCR 0.0094 0.0125 0.0174
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0371 0.0632 0.2386
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Plasmodium vivax vivapain-2 0.1522 0.2746 1
Echinococcus granulosus caspase 0.0116 0.0164 0.0164
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0762 0.1351 0.364
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0371 0.0632 0.2386
Brugia malayi cathepsin B-like cysteine proteinase 0.3921 0.7149 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1581 0.2854 0.3992
Echinococcus granulosus chromobox protein 1 0.0069 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0063 0.0068 0.0095
Echinococcus multilocularis neurogenic locus protein delta 0.003 0.0007 0.0007
Leishmania major hypothetical protein, conserved 0.0141 0.021 0.0566
Trypanosoma cruzi cysteine peptidase, putative 0.0467 0.0809 0.1131
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0075 0.0106
Giardia lamblia Pyruvate kinase 0.0033 0.0013 0.0048
Echinococcus granulosus caspase 3 0.0072 0.0084 0.0084
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0009 0.0009
Plasmodium falciparum cysteine proteinase falcipain 3 0.1522 0.2746 1
Echinococcus multilocularis fibrillin 1 0.0055 0.0053 0.0053
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Echinococcus multilocularis centrin 2 0.016 0.0246 0.0246
Entamoeba histolytica hypothetical protein, conserved 0.0164 0.0253 0.0921
Trypanosoma brucei cysteine peptidase, putative 0.0641 0.1128 0.3041
Trypanosoma brucei conserved protein 0.0234 0.0382 0.1028
Onchocerca volvulus 0.0109 0.0152 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0057 0.008
Entamoeba histolytica cysteine proteinase, putative 0.0837 0.1489 0.5422
Plasmodium falciparum serine repeat antigen 8 0.0371 0.0632 0.23
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1469 0.2647 0.9641
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0041 0.0058
Brugia malayi Muscleblind-like protein 0.0151 0.023 0.0321
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0962 0.1718 0.4628
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0008 0.003
Echinococcus granulosus enteropeptidase 0.0108 0.0151 0.0151
Schistosoma mansoni egf-like domain protein 0.0052 0.0047 0.0066
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0611 0.1073 0.15
Brugia malayi TAR-binding protein 0.0067 0.0075 0.0106
Echinococcus granulosus calumenin 0.0164 0.0253 0.0253
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0024 0.0999
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0055 0.0053 0.0074
Schistosoma mansoni cathepsin F (C01 family) 0.1522 0.2746 0.3841
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.0632 0.23
Loa Loa (eye worm) G-protein coupled receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Brugia malayi neuropeptide F receptor 0.0094 0.0125 0.0174
Echinococcus granulosus calpain 7 C02 family 0.1048 0.1874 0.1874
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.0045
Echinococcus multilocularis cysteine protease 0.1522 0.2746 0.2746
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Echinococcus granulosus programmed cell death protein 0.0188 0.0297 0.0297
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0009 0.0012
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.1048 0.1874 0.5051
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0041 0.0111
Onchocerca volvulus 0.0046 0.0036 0.013
Toxoplasma gondii aspartyl protease 0.0063 0.0068 0.0248
Giardia lamblia Hypothetical protein 0.0099 0.0134 0.0504
Toxoplasma gondii cathepsin CPC2 0.0371 0.0632 0.23
Echinococcus granulosus sodium channel protein 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0003 0.0004
Brugia malayi Heterochromatin protein 1 0.0069 0.0078 0.0108
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0007 0.0007
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0156 0.0237 0.064
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0049 0.0042 0.0042
Leishmania major calcium channel protein, putative,ion transporter, putative 0.004 0.0025 0.0066
Onchocerca volvulus Myosin regulatory light chain 2 homolog 0.0028 0.0003 0.001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0024 0.0556
Schistosoma mansoni cathepsin B (C01 family) 0.0371 0.0632 0.0884
Plasmodium falciparum serine repeat antigen 1 0.0371 0.0632 0.23
Plasmodium vivax unspecified product 0.0467 0.0809 0.2945
Brugia malayi calpain 5 0.0417 0.0716 0.1002
Echinococcus granulosus sex peptide receptor 0.0094 0.0125 0.0125
Echinococcus granulosus histone lysine methyltransferase setb 0.0096 0.0129 0.0129
Brugia malayi hypothetical protein 0.0041 0.0028 0.0038
Echinococcus granulosus calbindin 32 0.0164 0.0253 0.0253
Entamoeba histolytica cysteine proteinase, putative 0.0837 0.1489 0.5422
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0474 0.1278
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma brucei metacaspase 0.0044 0.0032 0.0087
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0116 0.0165 0.0231
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0108 0.0151 0.0211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Toxoplasma gondii hypothetical protein 0.0046 0.0036 0.013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1804 0.2523
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0009 0.0012
Trypanosoma brucei mitochondrial calcium uptake 1 0.016 0.0246 0.0662
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3921 0.7149 1
Trypanosoma brucei protein I/6 0.016 0.0246 0.0662
Toxoplasma gondii thioredoxin reductase 0.0102 0.0139 0.0506
Plasmodium falciparum plasmepsin IX 0.0063 0.0068 0.0248
Brugia malayi Hemopexin family protein 0.0035 0.0015 0.0022
Echinococcus multilocularis g-protein coupled receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1522 0.2746 0.3841
Schistosoma mansoni cathepsin s 0.0467 0.0809 0.1131
Echinococcus multilocularis neuropeptide receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0371 0.0632 0.23
Schistosoma mansoni hypothetical protein 0.0041 0.0028 0.0038
Entamoeba histolytica calmodulin, putative 0.016 0.0246 0.0895
Echinococcus multilocularis fmrfamide receptor 0.0094 0.0125 0.0125
Echinococcus granulosus geminin 0.0865 0.154 0.154
Onchocerca volvulus Peroxidase homolog 0.0109 0.0152 0.0553
Schistosoma mansoni ef hand domain family member A2 0.016 0.0246 0.0344
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma brucei Component of motile flagella 41 0.016 0.0246 0.0662
Mycobacterium ulcerans proteasome PrcB 0.0156 0.0237 1
Trichomonas vaginalis calpain, putative 0.0417 0.0716 0.2608
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0066
Brugia malayi Cathepsin L-like precursor 0.1522 0.2746 0.3841
Echinococcus granulosus calcyphosin protein 0.0028 0.0003 0.0003
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0465 0.0805 0.0805
Leishmania major prefoldin subunit, putative 0.0099 0.0134 0.036
Loa Loa (eye worm) matrixin family protein 0.0059 0.006 0.0085
Schistosoma mansoni hypothetical protein 0.0865 0.154 0.2154
Onchocerca volvulus 0.1391 0.2505 0.9121
Echinococcus multilocularis musashi 0.0057 0.0057 0.0057
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0116 0.0165 0.0231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0008 0.003
Brugia malayi Trypsin family protein 0.0279 0.0464 0.0649
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0078 0.0282
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Brugia malayi G protein-coupled receptor F59B2.13 0.0094 0.0125 0.0174
Brugia malayi cathepsin Z-like cysteine proteinase 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0089 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0371 0.0632 0.23
Echinococcus multilocularis proteasome (prosome, macropain) 0.0156 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Echinococcus multilocularis caspase 8 0.0044 0.0032 0.0032
Onchocerca volvulus 0.0098 0.0132 0.0481
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) AStacin protease 0.0057 0.0055 0.0078
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Toxoplasma gondii calmodulin CAM2 0.0028 0.0003 0.001
Brugia malayi putative neuropeptide receptor 0.0094 0.0125 0.0174
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Echinococcus multilocularis calumenin 0.0164 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1332 0.2397 0.3353
Echinococcus multilocularis peroxidasin 0.0109 0.0152 0.0152
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0008 0.003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0017 1
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Giardia lamblia Cathepsin L precursor 0.0371 0.0632 0.2386
Schistosoma mansoni neuropeptide receptor 0.0094 0.0125 0.0174
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0213 0.0343 0.0343
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0031 0.0113
Giardia lamblia Cathepsin B precursor 0.1469 0.2647 1
Plasmodium vivax myosin A tail domain interacting protein MTIP, putative 0.0028 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.1055 0.1889 0.2642
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0078 0.0108
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0013 0.0046
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0094 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1055 0.1889 0.6879
Echinococcus granulosus neuropeptide receptor A26 0.0094 0.0125 0.0125
Leishmania major cysteine peptidase A (CPA) 0.1522 0.2746 0.7399
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0009 0.0012
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.006 0.1415
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0031 0.0113
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0094 0.0125 0.0174
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0225 0.0364 0.0509
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0108 0.0151 0.0211
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0094 0.0125 0.0174
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0036 0.013
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0156 0.0237 0.0332
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Schistosoma mansoni laminin gamma-3 chain 0.003 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0004
Brugia malayi Cytochrome P450 family protein 0.0049 0.0041 0.0058
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.001 0.0014
Leishmania major proteasome beta 5 subunit, putative 0.0156 0.0237 0.064
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0467 0.0809 0.1131
Schistosoma mansoni hypothetical protein 0.0098 0.0132 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Plasmodium falciparum plasmepsin IV 0.0213 0.0343 0.125
Echinococcus multilocularis calmodulin 0.016 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.1055 0.1889 0.2642
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0023
Trypanosoma brucei Metacaspase-4 0.0044 0.0032 0.0087
Loa Loa (eye worm) cysteine protease 0.1522 0.2746 0.3841
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0003 0.0004
Toxoplasma gondii cathepsin CPL 0.1522 0.2746 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0009 0.0012
Brugia malayi Cathepsin L-like precursor 0.1055 0.1889 0.2642
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0009 0.0012
Onchocerca volvulus 0.0046 0.0036 0.013
Echinococcus granulosus dna polymerase eta 0.0049 0.0041 0.0041
Schistosoma mansoni opsin-like receptor 0.0094 0.0125 0.0174
Toxoplasma gondii troponin c, isotype gamma, putative 0.016 0.0246 0.0895
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0024 0.0024
Brugia malayi Pre-SET motif family protein 0.0096 0.0129 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Trypanosoma cruzi cysteine protease, putative 0.0837 0.1489 0.2083
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.016 0.0246 0.0344
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.0139 0.0139
Toxoplasma gondii proteasome subunit beta type, putative 0.0156 0.0237 0.0865
Onchocerca volvulus Cathepsin F homolog 0.1522 0.2746 1
Loa Loa (eye worm) fibroinase 0.1522 0.2746 0.3841
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0474 0.1278
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0225 0.0364 0.0509
Loa Loa (eye worm) programmed cell death protein 6 0.0164 0.0253 0.0354
Plasmodium falciparum serine repeat antigen 3 0.0371 0.0632 0.23
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Brugia malayi Protein kinase domain containing protein 0.0141 0.021 0.0294
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.0017 0.0699
Schistosoma mansoni notch 0.003 0.0007 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0311 0.0435
Echinococcus multilocularis dro:myosuppressin receptor 0.0094 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0214 0.0214
Brugia malayi calpain family protein 1 0.2439 0.4428 0.6193
Onchocerca volvulus 0.1055 0.1889 0.6879
Echinococcus multilocularis fat cadherin tumor suppressor 0.003 0.0007 0.0007
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Onchocerca volvulus 0.0094 0.0125 0.0454
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0371 0.0632 0.23
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0048 0.0174
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0641 0.1128 0.1578
Brugia malayi proteasome subunit beta type 2 0.0049 0.0042 0.0059
Echinococcus multilocularis notch 0.003 0.0007 0.0007
Onchocerca volvulus 0.0094 0.0125 0.0454
Loa Loa (eye worm) hypothetical protein 0.0063 0.0068 0.0095
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Entamoeba histolytica cysteine protease, putative 0.0371 0.0632 0.23
Onchocerca volvulus 0.0094 0.0125 0.0454
Echinococcus multilocularis Tolloid protein 1 0.0116 0.0165 0.0165
Giardia lamblia Hypothetical protein 0.0164 0.0253 0.0956
Echinococcus multilocularis g protein coupled receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0004
Echinococcus granulosus EF HAND 1 calcium binding site 0.016 0.0246 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1522 0.2746 1
Mycobacterium ulcerans hydrolase 0.003 0.0006 0.0272
Giardia lamblia Cysteine protease 0.0371 0.0632 0.2386
Brugia malayi Kringle domain containing protein 0.0141 0.021 0.0294
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.001 0.001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0661 0.1165 0.163
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Trypanosoma brucei proteasome beta 6 subunit 0.012 0.0172 0.0462
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0151 0.0211
Mycobacterium leprae Probable lipase LipE 0.0039 0.0024 0.0556
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0057 0.008
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.016 0.0246 0.0895
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0641 0.1128 0.3041
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0213 0.0343 0.048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0009 0.0012
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Echinococcus granulosus tissue type plasminogen activator 0.0141 0.021 0.021
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0024 0.0033
Schistosoma mansoni chromobox protein 0.0069 0.0078 0.0108
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0225 0.0364 0.0981
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Toxoplasma gondii cathepsin CPC1 0.0371 0.0632 0.23
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0622 0.1093 0.2945
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0024 0.0033
Schistosoma mansoni myosin regulatory light chain 0.0028 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0371 0.0632 0.23
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Onchocerca volvulus Matrilysin homolog 0.0054 0.0051 0.0187
Plasmodium falciparum plasmepsin X 0.0063 0.0068 0.0248
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0762 0.1351 0.189
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0233 0.0379 0.8882
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1332 0.2397 0.6459
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Trypanosoma brucei calmodulin, putative 0.0164 0.0253 0.0682
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1048 0.1874 0.2622
Schistosoma mansoni caspase-7 (C14 family) 0.0116 0.0164 0.023
Giardia lamblia High cysteine protein 0.003 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0467 0.0809 0.1131
Mycobacterium tuberculosis Probable dehydrogenase 0.0233 0.0379 0.8882
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Echinococcus multilocularis cathepsin L 0.0371 0.0632 0.0632
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0371 0.0632 0.0884
Echinococcus granulosus lamin dm0 0.0057 0.0057 0.0057
Trypanosoma brucei centrin-3 0.0188 0.0297 0.08
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0152 0.0212
Onchocerca volvulus 0.1522 0.2746 1
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0032 0.0087
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0371 0.0632 0.23
Echinococcus multilocularis neuropeptides capa receptor 0.0094 0.0125 0.0125
Brugia malayi Cathepsin L-like cysteine proteinase 0.1055 0.1889 0.2642
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Brugia malayi cathepsin F-like cysteine proteinase 0.0467 0.0809 0.1131
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0028 0.01
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0048 0.0067
Onchocerca volvulus 0.0041 0.0028 0.01
Trypanosoma brucei calpain-like protein, putative 0.1048 0.1874 0.5051
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0371 0.0632 0.23
Echinococcus multilocularis dnaJ subfamily B 0.0811 0.1441 0.1441
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0078 0.0282
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0006 0.0009
Loa Loa (eye worm) G-protein coupled receptor 0.0094 0.0125 0.0174
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.0017 0.0045
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0139 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.016 0.0246 0.0895
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0024 0.0089
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0762 0.1351 0.189
Brugia malayi larval opioid receptor 0.0094 0.0125 0.0174
Echinococcus multilocularis G protein coupled receptor 139 0.0094 0.0125 0.0125
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0417 0.0716 0.2608
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0013 0.0046
Plasmodium falciparum serine repeat antigen 7 0.0371 0.0632 0.23
Trichomonas vaginalis caltractin, putative 0.0028 0.0003 0.001
Leishmania major trypanothione reductase 0.0102 0.0139 0.0375
Echinococcus multilocularis protein jagged 1 0.003 0.0007 0.0007
Trypanosoma brucei small myristoylated protein 1-2 0.0387 0.0663 0.1786
Brugia malayi Papain family cysteine protease containing protein 0.0371 0.0632 0.0884
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0641 0.1128 0.1578
Echinococcus granulosus 7TM GPCR rhodopsin 0.0094 0.0125 0.0125
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0371 0.0632 0.2386
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis calpain 5 0.1048 0.1874 0.1874
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0259 0.0427 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0139 0.3258
Onchocerca volvulus Peroxidasin homolog 0.0109 0.0152 0.0553
Echinococcus multilocularis neural cadherin 0.003 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0039 0.0024 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0371 0.0632 0.23
Toxoplasma gondii microneme protein MIC17B 0.0046 0.0036 0.013
Onchocerca volvulus 0.0109 0.0152 0.0553
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0024 0.0024
Giardia lamblia Proteasome subunit beta type 1 0.012 0.0172 0.0648
Trichomonas vaginalis calpain, putative 0.0417 0.0716 0.2608
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0221 0.0221
Giardia lamblia Cysteine protease 0.0371 0.0632 0.2386
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0094 0.0125 0.0174
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0233 0.0379 0.8882
Loa Loa (eye worm) hypothetical protein 0.016 0.0246 0.0344
Loa Loa (eye worm) TK/ROR protein kinase 0.0141 0.021 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0009 0.0012
Onchocerca volvulus Cathepsin L homolog 0.1522 0.2746 1
Onchocerca volvulus 0.0046 0.0036 0.013
Echinococcus granulosus g protein coupled receptor 0.0094 0.0125 0.0125
Echinococcus multilocularis neuropeptide FF receptor 2 0.0094 0.0125 0.0125
Echinococcus multilocularis protein jagged 2 0.003 0.0007 0.0007
Schistosoma mansoni calmodulin-related 0.0028 0.0003 0.0004
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0032 0.0118
Brugia malayi G protein-coupled receptor 0.0094 0.0125 0.0174
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0701 0.1239 0.3338
Giardia lamblia Cathepsin B precursor 0.0371 0.0632 0.2386
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2599 0.4722 0.6604
Leishmania major hypothetical protein, conserved 0.0225 0.0364 0.0981
Brugia malayi Cathepsin L-like precursor 0.1055 0.1889 0.2642
Echinococcus granulosus neuropeptide receptor 0.0094 0.0125 0.0125
Brugia malayi RasGEF domain containing protein 0.0028 0.0003 0.0004
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0225 0.0364 0.0981
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Echinococcus granulosus laminin 0.0055 0.0053 0.0053
Echinococcus multilocularis Mastin 0.0108 0.0151 0.0151
Schistosoma mansoni calmodulin related calcium binding protein 0.016 0.0246 0.0344
Plasmodium falciparum calpain 0.0417 0.0716 0.2608
Brugia malayi neuropeptide F receptor 0.0094 0.0125 0.0174
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0015 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0156 0.0237 0.0897
Leishmania major hypothetical protein, conserved 0.0164 0.0253 0.0682
Brugia malayi RE15519p 0.0094 0.0125 0.0174
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0311 0.0435
Schistosoma mansoni amine GPCR 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Trichomonas vaginalis calcineurin B subunit, putative 0.016 0.0246 0.0895
Echinococcus granulosus cysteine protease 0.0837 0.1489 0.1489
Brugia malayi Calcium binding EGF domain containing protein 0.0033 0.0013 0.0018
Schistosoma mansoni pyruvate kinase 0.0033 0.0013 0.0018
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0094 0.0125 0.0174
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0049 0.0042 0.0152
Echinococcus granulosus fibropellin Ia 0.003 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Echinococcus granulosus 7tm_1 domain containing protein 0.0094 0.0125 0.0125
Entamoeba histolytica cysteine proteinase 1, putative 0.0837 0.1489 0.5422
Onchocerca volvulus 0.0279 0.0464 0.1689
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni cathepsin D (A01 family) 0.0596 0.1045 0.1462
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0024 0.0556
Echinococcus granulosus EF hand domain containing family member A2 0.0164 0.0253 0.0253
Loa Loa (eye worm) calpain family protein 1 0.2439 0.4428 0.6193
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0013 0.0018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Leishmania major small myristoylated protein 4, putative 0.0611 0.1073 0.289
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1253 0.2251 0.6066
Schistosoma mansoni lamin 0.0057 0.0057 0.008
Onchocerca volvulus 0.0108 0.0151 0.0549
Trypanosoma cruzi hypothetical protein, conserved 0.0141 0.021 0.0294
Brugia malayi Cathepsin L-like precursor 0.1522 0.2746 0.3841
Echinococcus granulosus serotonin receptor 0.0094 0.0125 0.0125
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0033 0.0013 0.0046
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3921 0.7149 1
Onchocerca volvulus 0.0094 0.0125 0.0454
Loa Loa (eye worm) hypothetical protein 0.1522 0.2746 0.3841
Trichomonas vaginalis calcium binding protein, putative 0.016 0.0246 0.0895
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Echinococcus multilocularis pyruvate kinase 0.0033 0.0013 0.0013
Echinococcus granulosus tumor protein p63 0.0326 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.1808 0.3269 0.4573
Entamoeba histolytica calmodulin, putative 0.0028 0.0003 0.001
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0622 0.1093 0.2945
Brugia malayi Trypsin family protein 0.0108 0.0151 0.0211
Toxoplasma gondii preprocathepsin c precursor, putative 0.0371 0.0632 0.23
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Echinococcus multilocularis caspase 0.0116 0.0164 0.0164
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0371 0.0632 0.23
Trypanosoma cruzi hypothetical protein, conserved 0.0364 0.062 0.0867
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0041 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0014
Plasmodium falciparum plasmepsin III 0.0063 0.0068 0.0248
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.016 0.0246 0.0344
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Toxoplasma gondii centrin family protein 0.0028 0.0003 0.001
Loa Loa (eye worm) calpain 5 0.0631 0.111 0.1553
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0017 0.0023
Brugia malayi calpain 5 0.0631 0.111 0.1553
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.012 0.0172 0.024
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0152 0.0212
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Plasmodium falciparum proteasome subunit beta type-5 0.0156 0.0237 0.0865
Leishmania major calmodulin, putative 0.016 0.0246 0.0662
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.0311 0.0435
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0028 0.01
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0213 0.0343 0.125
Loa Loa (eye worm) glutathione reductase 0.0102 0.0139 0.0194
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0225 0.0364 0.0509
Leishmania major small myristoylated protein-2 0.0706 0.1248 0.3362
Onchocerca volvulus 0.0171 0.0265 0.0964
Schistosoma mansoni hypothetical protein 0.0032 0.001 0.0014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3921 0.7149 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0371 0.0632 0.23
Onchocerca volvulus 0.003 0.0007 0.0026
Schistosoma mansoni calpain-7 (C02 family) 0.1048 0.1874 0.2622
Onchocerca volvulus 0.0094 0.0125 0.0454
Echinococcus multilocularis serotonin receptor 0.0094 0.0125 0.0125
Plasmodium vivax proteasome subunit beta type-2, putative 0.0049 0.0042 0.0152
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.016 0.0246 0.0895
Loa Loa (eye worm) cathepsin B 0.1469 0.2647 0.3703
Echinococcus multilocularis prefoldin subunit 6 0.0099 0.0134 0.0134
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0094 0.0125 0.0125
Brugia malayi MH2 domain containing protein 0.0372 0.0634 0.0887
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.0364 0.0509
Brugia malayi glutathione reductase 0.0102 0.0139 0.0194
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0417 0.0716 0.2608
Trypanosoma brucei cysteine peptidase C (CPC) 0.1469 0.2647 0.7133
Schistosoma mansoni cpg binding protein 0.0086 0.011 0.0154
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0797 0.1415 0.3813
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0017 0.0045
Echinococcus granulosus peroxidasin 0.0109 0.0152 0.0152
Giardia lamblia Hypothetical protein 0.0371 0.0632 0.2386
Schistosoma mansoni growth hormone secretagogue receptor 0.0094 0.0125 0.0174
Brugia malayi Cytochrome P450 family protein 0.006 0.0062 0.0086
Leishmania major protein kinase, putative 0.016 0.0246 0.0662
Onchocerca volvulus 0.0303 0.0507 0.1847
Echinococcus granulosus Calcium binding protein 0.0028 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Giardia lamblia Calmodulin 0.0028 0.0003 0.001
Echinococcus granulosus neurogenic locus protein delta 0.003 0.0007 0.0007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0008 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0008 0.003
Brugia malayi Serotonin receptor 0.0094 0.0125 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0009 0.0012
Echinococcus granulosus delta-like protein 1 0.003 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.003 0.0006 0.0009
Giardia lamblia Cathepsin B precursor 0.0371 0.0632 0.2386
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0371 0.0632 0.0884
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0009 0.0012
Brugia malayi Neuronal calcium sensor family protein 1 0.0028 0.0003 0.0004
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0213 0.0343 0.125
Brugia malayi proteasome subunit beta type 1 0.012 0.0172 0.024
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0052 0.0047 0.0066
Echinococcus multilocularis calpain 0.1048 0.1874 0.1874
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0152 0.0212
Loa Loa (eye worm) hypothetical protein 0.0041 0.0027 0.0037
Trypanosoma cruzi calmodulin, putative 0.016 0.0246 0.0344
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Entamoeba histolytica calmodulin, putative 0.016 0.0246 0.0895
Loa Loa (eye worm) histone methyltransferase 0.003 0.0007 0.001
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.016 0.0246 0.0662
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1009 0.1804 0.2523
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0028 0.0003 0.001
Brugia malayi G-protein coupled receptor 0.0094 0.0125 0.0174
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0009 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0094 0.0125 0.0174
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Onchocerca volvulus 0.003 0.0007 0.0026
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0049 0.0042 0.0152
Echinococcus multilocularis programmed cell death protein 0.0188 0.0297 0.0297
Brugia malayi Latrophilin receptor protein 2 0.0032 0.001 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0009 0.0012
Loa Loa (eye worm) myosin regulatory light chain 1 0.0028 0.0003 0.0004
Echinococcus granulosus neuropeptide s receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0247 0.0405 0.0566
Giardia lamblia Cathepsin L precursor 0.0371 0.0632 0.2386
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0465 0.0805 0.1126
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0233 0.0379 0.8882
Echinococcus granulosus cathepsin l1 0.1522 0.2746 0.2746
Echinococcus multilocularis EF hand domain containing family member A2 0.016 0.0246 0.0246
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.001 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.0364 0.0509
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Plasmodium falciparum prefoldin subunit 6, putative 0.0099 0.0134 0.0486
Loa Loa (eye worm) hypothetical protein 0.0039 0.0024 0.0033
Brugia malayi Thioredoxin reductase 0.0102 0.0139 0.0194
Toxoplasma gondii calmodulin CAM1 0.0164 0.0253 0.0921
Schistosoma mansoni calpain-7 (C02 family) 0.1048 0.1874 0.2622
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0009 0.0012
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0036 0.013
Toxoplasma gondii EF hand domain-containing protein 0.0028 0.0003 0.001
Brugia malayi Papain family cysteine protease containing protein 0.0371 0.0632 0.0884
Trypanosoma brucei calpain-like protein, putative 0.1332 0.2397 0.6459
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.006 0.022
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0285 0.0474 0.1278
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.012 0.0172 0.0172
Schistosoma mansoni biogenic amine receptor 0.0094 0.0125 0.0174
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.016 0.0246 0.0344
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Mycobacterium leprae PROBABLE HYDROLASE 0.003 0.0006 0.0151
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0062 0.0086
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0024 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0164 0.0253 0.0921
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0041 0.0058
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0371 0.0632 0.23
Loa Loa (eye worm) hypothetical protein 0.0151 0.023 0.0321
Echinococcus multilocularis orexin receptor type 2 0.0094 0.0125 0.0125
Brugia malayi hypothetical protein 0.0034 0.0014 0.0019
Brugia malayi ORL1-like opioid receptor 0.0094 0.0125 0.0174
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0045
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0041 0.0058
Onchocerca volvulus 0.0094 0.0125 0.0454
Trypanosoma brucei hypothetical protein, conserved 0.016 0.0246 0.0662
Schistosoma mansoni adenoreceptor 0.0094 0.0125 0.0174
Brugia malayi Papain family cysteine protease containing protein 0.1522 0.2746 0.3841
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0008 0.003
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0022 0.0081
Trichomonas vaginalis calcium binding protein, putative 0.016 0.0246 0.0895
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0002 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0371 0.0632 0.23
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0094 0.0125 0.0174
Entamoeba histolytica protein kinase, putative 0.0631 0.111 0.4042
Brugia malayi Calcium binding EGF domain containing protein 0.0055 0.0053 0.0074
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0094 0.0125 0.0174
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.0017 0.006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0024 0.0556
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Plasmodium falciparum metacaspase 1 0.0044 0.0032 0.0118
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1522 0.2746 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0024 0.0033
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.01 0.0135 0.0189
Schistosoma mansoni hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0075 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0371 0.0632 0.23
Schistosoma mansoni hypothetical protein 0.0141 0.021 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0036 0.005
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0213 0.0343 0.048
Schistosoma mansoni hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.0118
Schistosoma mansoni hypothetical protein 0.0137 0.0204 0.0285
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.016 0.0246 0.0895
Brugia malayi GCC2 and GCC3 family protein 0.0033 0.0013 0.0018
Mycobacterium tuberculosis Probable reductase 0.0233 0.0379 0.8882
Brugia malayi calpain 7 0.1048 0.1874 0.2622
Plasmodium vivax proteasome subunit beta type-1, putative 0.012 0.0172 0.0625
Toxoplasma gondii cathepsin B 0.1469 0.2647 0.9641
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Plasmodium vivax serine-repeat antigen (SERA) 0.0371 0.0632 0.23
Onchocerca volvulus 0.016 0.0246 0.0895
Trypanosoma cruzi cysteine peptidase, putative 0.2048 0.3711 0.5191
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Trypanosoma cruzi I/6 autoantigen, putative 0.016 0.0246 0.0344
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.0017 0.006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma brucei prefoldin subunit, putative 0.0099 0.0134 0.036
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0328 0.0554 0.0775
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0013 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni calpain C (C02 family) 0.1048 0.1874 0.2622
Toxoplasma gondii hypothetical protein 0.0046 0.0036 0.013
Onchocerca volvulus 0.0086 0.011 0.04
Onchocerca volvulus 0.0141 0.021 0.0765
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0371 0.0632 0.23
Leishmania major hypothetical protein, conserved 0.0225 0.0364 0.0981
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0009 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0094 0.0125 0.0125
Echinococcus granulosus g protein coupled receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0036 0.005
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.0017 0.006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni notch 0.003 0.0007 0.001
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0371 0.0632 0.0884
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis centrin, putative 0.0028 0.0003 0.001
Echinococcus multilocularis sex peptide receptor 0.0094 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.016 0.0246 0.0344
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0049 0.0042 0.0152
Echinococcus granulosus fmrfamide receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) EF hand family protein 0.016 0.0246 0.0344
Onchocerca volvulus Matrix metalloproteinase homolog 0.0054 0.0051 0.0187
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0049 0.0042 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0129 0.018
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0962 0.1718 0.4628
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0041 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1332 0.2397 0.6459
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2599 0.4722 0.4722
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.006 0.0163
Schistosoma mansoni chromobox protein 0.0069 0.0078 0.0108
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0094 0.0125 0.0174
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.0017 0.0023
Trypanosoma cruzi small myristoylated protein 1-1 0.0387 0.0663 0.0927
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.0039 0.0024 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1804 0.486
Schistosoma mansoni reticulocalbin 0.016 0.0246 0.0344
Plasmodium falciparum glutathione reductase 0.0035 0.0017 0.006
Schistosoma mansoni calpain (C02 family) 0.1048 0.1874 0.2622
Brugia malayi Cathepsin L-like precursor 0.1522 0.2746 0.3841
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Mycobacterium tuberculosis Probable oxidoreductase 0.0259 0.0427 1
Onchocerca volvulus 0.0094 0.0125 0.0454
Echinococcus multilocularis allatostatin A receptor 0.0094 0.0125 0.0125
Schistosoma mansoni neuropeptide F-like receptor 0.0094 0.0125 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0009 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1804 0.486
Brugia malayi Cathepsin L-like precursor 0.1522 0.2746 0.3841
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0009 0.0009
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0164 0.0253 0.0354
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0057 0.008
Loa Loa (eye worm) melatonin receptor type 1A 0.0094 0.0125 0.0174
Echinococcus granulosus GPCR family 2 0.0032 0.001 0.001
Loa Loa (eye worm) myosin Light Chain family member 0.0032 0.001 0.0014
Plasmodium vivax aspartyl protease, putative 0.0063 0.0068 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0009 0.0012
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0049 0.0042 0.0042
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1522 0.2746 1
Leishmania major hypothetical protein, unknown function 0.0417 0.0716 0.193
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Schistosoma mansoni hypothetical protein 0.0099 0.0134 0.0187
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0032 0.0118
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0094 0.0125 0.0174
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0009 0.0009
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0024 0.0556
Echinococcus granulosus caspase 2 0.0085 0.0108 0.0108
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0641 0.1128 0.1578
Leishmania major hypothetical protein, conserved 0.0225 0.0364 0.0981
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Giardia lamblia Programmed cell death protein-like protein 0.0028 0.0003 0.001
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1332 0.2397 0.3353
Echinococcus multilocularis calcium uptake protein 1 0.0164 0.0253 0.0253
Loa Loa (eye worm) neuropeptide F receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0009 0.0012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1253 0.2251 0.3149
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0024 0.0033
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Loa Loa (eye worm) Notch2 0.0033 0.0013 0.0018
Onchocerca volvulus 0.0039 0.0024 0.0086
Echinococcus granulosus proteasome prosome macropain 0.0156 0.0237 0.0237
Giardia lamblia Cathepsin L precursor 0.0371 0.0632 0.2386
Brugia malayi beta-lactamase family protein 0.0039 0.0024 0.0033
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0009 0.0032
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0013 0.0046
Schistosoma mansoni hypothetical protein 0.016 0.0246 0.0344
Trichomonas vaginalis calmodulin, putative 0.0164 0.0253 0.0921
Onchocerca volvulus 0.003 0.0007 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0009 0.0012
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0094 0.0125 0.0174
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni neuronal calcium sensor 0.016 0.0246 0.0344
Trichomonas vaginalis calmodulin-2, putative 0.016 0.0246 0.0895
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1332 0.2397 0.6459
Brugia malayi EF hand family protein 0.0164 0.0253 0.0354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Leishmania major cathepsin L-like protease 0.1522 0.2746 0.7399
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis calbindin 32 0.0164 0.0253 0.0253
Trypanosoma brucei centrin, putative 0.016 0.0246 0.0662
Loa Loa (eye worm) hypothetical protein 0.0056 0.0055 0.0077
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Plasmodium vivax calpain, putative 0.1048 0.1874 0.6826
Trypanosoma brucei caltractin, putative 0.0188 0.0297 0.08
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0008 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0129 0.0469
Echinococcus multilocularis neurogenic locus notch protein 0.003 0.0007 0.0007
Schistosoma mansoni calmodulin 0.016 0.0246 0.0344
Brugia malayi Dopamine receptor 0.0094 0.0125 0.0174
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0371 0.0632 0.2386
Echinococcus multilocularis neuronal calcium sensor 0.016 0.0246 0.0246
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.016 0.0246 0.0344
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0013 0.0034
Plasmodium vivax vivapain-3 0.0837 0.1489 0.5422
Echinococcus granulosus Mastin 0.0108 0.0151 0.0151
Echinococcus multilocularis cathepsin b 0.3921 0.7149 0.7149
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0009 0.0009
Loa Loa (eye worm) ctsf protein 0.1522 0.2746 0.3841
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0328 0.0554 0.0775
Mycobacterium tuberculosis Conserved protein 0.0039 0.0024 0.0556
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Toxoplasma gondii PAN/Apple domain-containing protein 0.0046 0.0036 0.013
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.0017 0.006
Leishmania major metacaspase, putative 0.0044 0.0032 0.0087
Echinococcus multilocularis hypothetical protein 0.1048 0.1874 0.1874
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0009 0.0009
Brugia malayi Trypsin-like protease protein 5 0.0108 0.0151 0.0211
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1332 0.2397 0.3353
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0009 0.0012
Echinococcus granulosus sarcoplasmic calcium binding protein 0.016 0.0246 0.0246
Entamoeba histolytica proteasome subunit beta type 1, putative 0.012 0.0172 0.0625
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Brugia malayi putative neuropeptide receptor NPR1 0.0094 0.0125 0.0174
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.0132 0.0185
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0052 0.0047 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.0364 0.0509
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Brugia malayi Cathepsin L-like precursor 0.0467 0.0809 0.1131
Echinococcus granulosus calmodulin 0.016 0.0246 0.0246
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0075 0.0106
Onchocerca volvulus 0.0164 0.0253 0.0921
Brugia malayi Proteasome A-type and B-type family protein 0.0156 0.0237 0.0332
Trypanosoma brucei hypothetical protein, conserved 0.0364 0.062 0.1669
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Echinococcus granulosus cpg binding protein 0.0091 0.0119 0.0119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0024 0.0033
Onchocerca volvulus Dual oxidase homolog 0.0109 0.0152 0.0553
Brugia malayi beta-lactamase 0.0039 0.0024 0.0033
Leishmania major cathepsin L-like protease 0.2048 0.3711 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0417 0.0716 0.2608
Brugia malayi Dopamine receptor protein 2 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0099 0.0134 0.0187
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0151 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Leishmania major hypothetical protein, conserved 0.0052 0.0048 0.0128
Brugia malayi Trypsin family protein 0.0108 0.0151 0.0211
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0371 0.0632 0.23
Loa Loa (eye worm) hypothetical protein 0.0213 0.0343 0.048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0009 0.0009
Giardia lamblia Cathepsin B precursor 0.0371 0.0632 0.2386
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0009 0.0012
Leishmania major cathepsin L-like protease 0.1522 0.2746 0.7399
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0259 0.0427 1
Echinococcus multilocularis cpg binding protein 0.0091 0.0119 0.0119
Onchocerca volvulus 0.1522 0.2746 1
Schistosoma mansoni hypothetical protein 0.0032 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.1055 0.1889 0.2642
Brugia malayi Papain family cysteine protease containing protein 0.0837 0.1489 0.2083
Loa Loa (eye worm) hypothetical protein 0.0346 0.0587 0.082
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0036 0.013
Onchocerca volvulus Cell death protein 3 homolog 0.0085 0.0108 0.0394
Loa Loa (eye worm) hypothetical protein 0.3921 0.7149 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0094 0.0125 0.0454
Mycobacterium ulcerans beta-lactamase 0.0039 0.0024 0.0999
Echinococcus multilocularis EF hand domain containing family member A2 0.0164 0.0253 0.0253
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0151 0.0151
Onchocerca volvulus 0.0094 0.0125 0.0454
Onchocerca volvulus 0.0039 0.0024 0.0086
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.0017 0.0389
Echinococcus granulosus tar DNA binding protein 0.0067 0.0075 0.0075
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0048 0.0174
Onchocerca volvulus 0.0108 0.0151 0.0549
Trichomonas vaginalis calmodulin, putative 0.0028 0.0003 0.001
Giardia lamblia Cathepsin B precursor 0.1469 0.2647 1
Onchocerca volvulus 0.0094 0.0125 0.0454
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Schistosoma mansoni neuronal calcium sensor 0.016 0.0246 0.0344
Echinococcus granulosus calpain A 0.1048 0.1874 0.1874
Echinococcus multilocularis neurogenic locus notch protein 4 0.003 0.0007 0.0007
Brugia malayi G-protein coupled receptor 0.0094 0.0125 0.0174
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0009 0.0009
Trypanosoma cruzi calmodulin, putative 0.016 0.0246 0.0344
Schistosoma mansoni cpg binding protein 0.0091 0.0119 0.0166
Leishmania major receptor-type adenylate cyclase a-like protein 0.0225 0.0364 0.0981
Schistosoma mansoni biogenic amine receptor 0.0094 0.0125 0.0174
Leishmania major calcineurin B subunit, putative 0.016 0.0246 0.0662
Plasmodium vivax aspartyl protease, putative 0.0063 0.0068 0.0248
Schistosoma mansoni cathepsin S (C01 family) 0.0371 0.0632 0.0884
Schistosoma mansoni rab 0.016 0.0246 0.0344
Schistosoma mansoni memapsin-2 (A01 family) 0.0471 0.0817 0.1142
Plasmodium vivax centrin-1, putative 0.016 0.0246 0.0895
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0641 0.1128 0.1578
Echinococcus multilocularis pyruvate kinase 0.0033 0.0013 0.0013
Mycobacterium tuberculosis Conserved protein 0.0039 0.0024 0.0556
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Trypanosoma brucei Calpain-like protein 1.1 0.1009 0.1804 0.486
Trypanosoma brucei calpain, putative 0.0701 0.1239 0.3338
Trypanosoma cruzi cysteine peptidase, putative 0.0837 0.1489 0.2083
Plasmodium vivax aspartyl proteinase, putative 0.0213 0.0343 0.125
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1804 0.2523
Brugia malayi Muscle positioning protein 4 0.0033 0.0013 0.0018
Echinococcus granulosus notch 0.003 0.0007 0.0007
Trypanosoma brucei I/6 autoantigen 0.016 0.0246 0.0662
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0151 0.0211
Schistosoma mansoni hypothetical protein 0.0108 0.0151 0.0211
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0009 0.0012
Trypanosoma cruzi major cysteine proteinase, putative 0.0371 0.0632 0.0884
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.0045
Trypanosoma cruzi centrin-3 0.0188 0.0297 0.0415
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trypanosoma cruzi cysteine proteinase, putative 0.0837 0.1489 0.2083
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0122 0.0175 0.0245
Schistosoma mansoni hypothetical protein 0.0811 0.1441 0.2015
Schistosoma mansoni histamine h1 receptor 0.0094 0.0125 0.0174
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0156 0.0237 0.0332
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.011 0.0154
Brugia malayi ecdysteroid receptor 0.0031 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0068 0.0077 0.0108
Brugia malayi hypothetical protein 0.0133 0.0195 0.0273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0009 0.0012
Brugia malayi KE2 family protein 0.0099 0.0134 0.0187
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0371 0.0632 0.23
Echinococcus granulosus protein jagged 1 0.003 0.0007 0.0007
Plasmodium falciparum plasmepsin VII 0.0063 0.0068 0.0248
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0024 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Echinococcus multilocularis thyroid hormone receptor alpha 0.0168 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0094 0.0125 0.0174
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0009 0.0009
Brugia malayi fibroinase precursor 0.0371 0.0632 0.0884
Leishmania major small myristoylated protein-3, putative 0.0328 0.0554 0.1493
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.012 0.0172 0.0625
Echinococcus granulosus lamin 0.0057 0.0057 0.0057
Plasmodium vivax aspartyl proteinase, putative 0.0063 0.0068 0.0248
Trichomonas vaginalis calcium binding protein, putative 0.016 0.0246 0.0895
Trypanosoma brucei calpain-like protein, putative 0.1048 0.1874 0.5051
Brugia malayi aspartic protease BmAsp-2, identical 0.0063 0.0068 0.0095
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0094 0.0125 0.0174
Onchocerca volvulus 0.0094 0.0125 0.0454
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0023
Echinococcus multilocularis cathepsin b 0.3921 0.7149 0.7149
Loa Loa (eye worm) hypothetical protein 0.0417 0.0716 0.1002
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0285 0.0474 0.1278
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0032 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.0118
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0135 0.0189
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0417 0.0716 0.2608
Leishmania major cathepsin L-like protease 0.2048 0.3711 1
Echinococcus granulosus neurogenic locus notch protein 0.0033 0.0013 0.0013
Onchocerca volvulus 0.0046 0.0036 0.013
Leishmania major cathepsin L-like protease 0.1522 0.2746 0.7399
Leishmania major META domain containing protein 0.0225 0.0364 0.0981
Echinococcus granulosus neuropeptide receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0303 0.0507 0.0709
Schistosoma mansoni opsin-like receptor 0.0094 0.0125 0.0174
Onchocerca volvulus Neuropeptide F receptor homolog 0.0094 0.0125 0.0454
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.0017 0.0045
Brugia malayi CXXC zinc finger family protein 0.0086 0.011 0.0154
Trypanosoma brucei small myristoylated protein 1-1 0.0387 0.0663 0.1786
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0898 0.16 0.4311
Onchocerca volvulus 0.0035 0.0015 0.0056
Echinococcus granulosus cathepsin b 0.3921 0.7149 0.7149
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0371 0.0632 0.0884
Echinococcus granulosus tm gpcr rhodopsin 0.0094 0.0125 0.0125
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0013 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0013 0.0046
Onchocerca volvulus Cathepsin L homolog 0.0371 0.0632 0.23
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0837 0.1489 0.5422
Onchocerca volvulus 0.003 0.0007 0.0026
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0417 0.0717 0.1932
Schistosoma mansoni lamin 0.0057 0.0057 0.008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0593 0.1039 0.1454
Onchocerca volvulus 0.0057 0.0057 0.0207
Loa Loa (eye worm) hypothetical protein 0.0482 0.0836 0.1169
Echinococcus multilocularis G-protein coupled receptor, putative 0.0094 0.0125 0.0125
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0094 0.0125 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Leishmania major hypothetical protein, conserved 0.0039 0.0024 0.0064
Schistosoma mansoni notch 0.003 0.0007 0.001
Echinococcus multilocularis transmembrane protease serine 3 0.0108 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni cathepsin D (A01 family) 0.0596 0.1045 0.1462
Echinococcus multilocularis laminin 0.0055 0.0053 0.0053
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0024 0.0556
Toxoplasma gondii EFHC1, putative 0.016 0.0246 0.0895
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0032 0.0045
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0099 0.0099
Echinococcus granulosus cathepsin l1 0.1055 0.1889 0.1889
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.0017 0.0045
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0417 0.0716 0.2608
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.2439 0.4428 0.6193
Plasmodium falciparum pyruvate kinase 0.0033 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.2022 0.3663 0.5124
Loa Loa (eye worm) beta-lactamase 0.0039 0.0024 0.0033
Onchocerca volvulus 0.0094 0.0125 0.0454
Mycobacterium ulcerans lipase LipD 0.0039 0.0024 0.0999
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.0017 0.0017
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0036 0.013
Leishmania major centrin, putative 0.016 0.0246 0.0662
Echinococcus granulosus allatostatin A receptor 0.0094 0.0125 0.0125
Schistosoma mansoni thyroid hormone receptor 0.0168 0.0261 0.0365
Echinococcus multilocularis calpain 7 (C02 family) 0.1048 0.1874 0.1874
Schistosoma mansoni calmodulin 0.016 0.0246 0.0344
Treponema pallidum NADH oxidase 0.0035 0.0017 0.5
Plasmodium vivax metacaspase 1, putative 0.0044 0.0032 0.0118
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0641 0.1128 0.3041
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Toxoplasma gondii microneme protein MIC4 0.0046 0.0036 0.013
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.012 0.0172 0.024
Schistosoma mansoni septate junction protein 0.003 0.0007 0.001
Trypanosoma brucei trypanothione reductase 0.0102 0.0139 0.0375
Echinococcus multilocularis lamin 0.0057 0.0057 0.0057
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0094 0.0125 0.0125
Leishmania major hypothetical protein, conserved 0.0225 0.0364 0.0981
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0099 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0108 0.0149 0.0209
Leishmania major calmodulin-like protein 0.016 0.0246 0.0662
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0028 0.0028
Echinococcus multilocularis calcyphosin protein 0.0028 0.0003 0.0003
Loa Loa (eye worm) notch protein 0.0033 0.0013 0.0018
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0108 0.0151 0.0151
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0096 0.0129 0.0129
Trichomonas vaginalis calmodulin, putative 0.0188 0.0297 0.1081
Brugia malayi steroid hormone receptor 0.0031 0.0009 0.0012
Plasmodium falciparum plasmepsin VIII, putative 0.0063 0.0068 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.001
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1048 0.1874 0.2622
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0032 0.001 0.0014
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0467 0.0809 0.1131
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0094 0.0125 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0328 0.0554 0.1493
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) proteasome subunit beta type 1 0.012 0.0172 0.024
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0156 0.0237 0.0865
Brugia malayi calpain family protein 1 0.2439 0.4428 0.6193
Brugia malayi hypothetical protein 0.0108 0.0151 0.0211
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0094 0.0125 0.0125
Brugia malayi follicle stimulating hormone receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1235 0.2218 0.3103
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.006 0.006
Echinococcus multilocularis caspase 2 0.0085 0.0108 0.0108
Mycobacterium ulcerans hypothetical protein 0.0108 0.0151 0.6352
Schistosoma mansoni neuropeptide receptor 0.0094 0.0125 0.0174
Schistosoma mansoni pyruvate kinase 0.0033 0.0013 0.0018
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Giardia lamblia Cathepsin L-like protease 0.0371 0.0632 0.2386
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0036 0.013
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0013 0.0299
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0017 0.0023
Echinococcus multilocularis programmed cell death protein 6 0.0032 0.001 0.001
Toxoplasma gondii calcium binding protein precursor, putative 0.0028 0.0003 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0094 0.0125 0.0125
Trypanosoma cruzi centrin, putative 0.0188 0.0297 0.0415
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0152 0.0212
Schistosoma mansoni peroxidasin 0.0109 0.0152 0.0212
Toxoplasma gondii proteasome subunit beta type 1, putative 0.012 0.0172 0.0625
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0094 0.0125 0.0174
Plasmodium falciparum plasmepsin II 0.0213 0.0343 0.125
Trypanosoma brucei metacaspase MCA2 0.0044 0.0032 0.0087
Schistosoma mansoni hypothetical protein 0.0094 0.0125 0.0174
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0094 0.0125 0.0174
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0009 0.0009
Onchocerca volvulus 0.1522 0.2746 1
Echinococcus multilocularis tumor protein p63 0.0326 0.0551 0.0551
Plasmodium vivax vivapain-2 0.1522 0.2746 1
Leishmania major cathepsin L-like protease 0.2048 0.3711 1
Schistosoma mansoni cathepsin C 0.0371 0.0632 0.0884
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Schistosoma mansoni neuronal calcium sensor 0.016 0.0246 0.0344
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Entamoeba histolytica cysteine protease, putative 0.0371 0.0632 0.23
Schistosoma mansoni calpain-2 (C02 family) 0.0417 0.0716 0.1002
Echinococcus granulosus neurogenic locus notch protein 0.003 0.0007 0.0007
Echinococcus multilocularis calmodulin 0.016 0.0246 0.0246
Brugia malayi EF hand family protein 0.016 0.0246 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0009 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0371 0.0632 0.23
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0287 0.0478 0.0669
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis hypothetical protein 0.0417 0.0716 0.2608
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1048 0.1874 0.2622
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0023
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0028 0.0028
Brugia malayi Eukaryotic aspartyl protease family protein 0.0063 0.0068 0.0095
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0075 0.0106
Loa Loa (eye worm) hypothetical protein 0.0055 0.0053 0.0074
Plasmodium falciparum serine repeat antigen 6 0.0371 0.0632 0.23
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Trichomonas vaginalis caltractin, putative 0.0028 0.0003 0.001
Plasmodium falciparum cysteine proteinase falcipain 1 0.0837 0.1489 0.5422
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.0118
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0094 0.0125 0.0174
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0116 0.0165 0.0231
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0023
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.016 0.0246 0.0344
Onchocerca volvulus 0.0108 0.0151 0.0549
Leishmania major centrin, putative 0.016 0.0246 0.0662
Echinococcus multilocularis glycoprotein Antigen 5 0.0108 0.0151 0.0151
Onchocerca volvulus 0.0063 0.0068 0.0248
Loa Loa (eye worm) hypothetical protein 0.0039 0.0024 0.0033
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2599 0.4722 0.6604
Brugia malayi Papain family cysteine protease containing protein 0.0837 0.1489 0.2083
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.0017 0.0045
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1804 0.486
Loa Loa (eye worm) proteasome subunit beta type 2 0.0049 0.0042 0.0059
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0008 0.003
Trichomonas vaginalis centrin, putative 0.0028 0.0003 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0031 0.0031
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0371 0.0632 0.23
Onchocerca volvulus Arrow homolog 0.0052 0.0047 0.0172
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0622 0.1093 0.1529
Brugia malayi PAN domain containing protein 0.0046 0.0036 0.005
Entamoeba histolytica cysteine proteinase 2 0.0837 0.1489 0.5422
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0129 0.0129
Loa Loa (eye worm) calpain 0.1048 0.1874 0.2622
Loa Loa (eye worm) hypothetical protein 0.0041 0.0028 0.0038
Echinococcus multilocularis neurogenic locus protein delta 0.003 0.0007 0.0007
Loa Loa (eye worm) blistered cuticle protein 3 0.0109 0.0152 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.2048 0.3711 0.5191
Echinococcus granulosus hypothetical protein 0.0094 0.0125 0.0125
Schistosoma mansoni alpha-1 adrenergic receptor 0.0094 0.0125 0.0174
Trypanosoma cruzi cruzipain precursor, putative 0.2048 0.3711 0.5191
Echinococcus multilocularis EF HAND 1, calcium binding site 0.016 0.0246 0.0246
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0371 0.0632 0.23
Echinococcus granulosus pyruvate kinase 0.0033 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0225 0.0364 0.0981
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0371 0.0632 0.0884
Echinococcus multilocularis neuropeptide s receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.1391 0.2505 0.3504
Loa Loa (eye worm) hypothetical protein 0.0371 0.0632 0.0884
Onchocerca volvulus 0.0028 0.0003 0.001
Entamoeba histolytica cysteine protease, putative 0.0371 0.0632 0.23
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0009 0.0012
Toxoplasma gondii hypothetical protein 0.0417 0.0716 0.2608
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Trypanosoma brucei metacaspase MCA3 0.0044 0.0032 0.0087
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0141 0.021 0.0765
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0962 0.1718 0.4628
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Leishmania major programmed cell death 6 protein-like protein 0.016 0.0246 0.0662
Plasmodium falciparum glutathione reductase 0.0102 0.0139 0.0506
Entamoeba histolytica grainin 2 0.0028 0.0003 0.001
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0837 0.1489 0.2083
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1469 0.2647 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0134 0.0486
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0009 0.0012
Onchocerca volvulus 0.0046 0.0036 0.013
Echinococcus multilocularis enteropeptidase 0.0108 0.0151 0.0151
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0009 0.0009
Brugia malayi calpain D 0.0417 0.0716 0.1002
Echinococcus granulosus pyruvate kinase 0.0033 0.0013 0.0013
Onchocerca volvulus 0.0033 0.0013 0.0046
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0008 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0371 0.0632 0.23
Echinococcus multilocularis expressed protein 0.0361 0.0614 0.0614
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0371 0.0632 0.23
Brugia malayi aspartic protease BmAsp-1, identical 0.0063 0.0068 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Plasmodium falciparum plasmepsin I 0.0213 0.0343 0.125
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0024 0.0086
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0641 0.1128 0.1578
Echinococcus multilocularis Calcium binding protein 0.0028 0.0003 0.0003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1009 0.1804 0.486
Brugia malayi hypothetical protein 0.0303 0.0507 0.0709
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0152 0.0212
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0094 0.0125 0.0174
Toxoplasma gondii aspartyl protease ASP1 0.0213 0.0343 0.125
Brugia malayi cathepsin L-like precursor 0.1055 0.1889 0.2642
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.016 0.0246 0.0246
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0009 0.0012
Onchocerca volvulus 0.0094 0.0125 0.0454
Brugia malayi Blistered cuticle protein 3 0.0109 0.0152 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Echinococcus multilocularis calpain A 0.2603 0.4729 0.4729
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0049 0.0042 0.0152
Echinococcus multilocularis caspase 3 0.0072 0.0084 0.0084
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0032 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0417 0.0716 0.193
Echinococcus granulosus somatostatin receptor 0.0094 0.0125 0.0125
Plasmodium falciparum serine repeat antigen 4 0.0371 0.0632 0.23
Trichomonas vaginalis conserved hypothetical protein 0.0364 0.062 0.2256
Onchocerca volvulus 0.0039 0.0024 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0371 0.0632 0.23
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0225 0.0364 0.0981
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0116 0.0164 0.0164
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0094 0.0125 0.0125
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.176 0.3182 0.3182
Trypanosoma cruzi I/6 autoantigen, putative 0.016 0.0246 0.0344
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0009 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.006 0.2543
Toxoplasma gondii ABC1 family protein 0.0039 0.0024 0.0086
Leishmania major hypothetical protein, conserved 0.016 0.0246 0.0662
Echinococcus multilocularis GPCR, family 2 0.0032 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Plasmodium vivax plasmepsin V, putative 0.0063 0.0068 0.0248
Toxoplasma gondii calcium binding egf domain-containing protein 0.0055 0.0053 0.0192
Echinococcus granulosus cathepsin L cysteine protease 0.0837 0.1489 0.1489
Onchocerca volvulus 0.0108 0.0149 0.0544
Echinococcus multilocularis survival motor neuron protein 1 0.0482 0.0836 0.0836
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.0017 0.0699
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0094 0.0125 0.0125
Onchocerca volvulus 0.0094 0.0125 0.0454
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3921 0.7149 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0009 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0371 0.0632 0.23
Loa Loa (eye worm) calpain family protein 1 0.1808 0.3269 0.4573
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0247 0.0405 0.0566
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1469 0.2647 0.7133
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0233 0.0379 0.8882
Trichomonas vaginalis myosin light chain 1, putative 0.016 0.0246 0.0895
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0311 0.0311
Trichomonas vaginalis centrin, putative 0.016 0.0246 0.0895
Loa Loa (eye worm) hypothetical protein 0.0371 0.0632 0.0884
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1522 0.2746 0.2746
Toxoplasma gondii EF hand domain-containing protein 0.016 0.0246 0.0895
Echinococcus granulosus calpain 5 0.1048 0.1874 0.1874
Loa Loa (eye worm) hypothetical protein 0.0141 0.021 0.0294
Echinococcus multilocularis chromobox protein 1 0.0069 0.0078 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Brugia malayi RNA binding protein 0.0067 0.0075 0.0106
Trichomonas vaginalis calcium binding protein, putative 0.0028 0.0003 0.001
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0049 0.0042 0.0113
Onchocerca volvulus 0.0109 0.0152 0.0553
Brugia malayi notch-like transmembrane receptor 0.003 0.0007 0.001
Onchocerca volvulus Cathepsin L homolog 0.1522 0.2746 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0151 0.0211
Toxoplasma gondii EGF family domain-containing protein 0.003 0.0007 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0837 0.1489 0.4012
Loa Loa (eye worm) DEAH box polypeptide 35 0.0032 0.001 0.0014
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0279 0.0464 0.0649
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0002 0.0002
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0009 0.0012
Trypanosoma cruzi prefoldin subunit, putative 0.0099 0.0134 0.0187
Trypanosoma cruzi prefoldin subunit, putative 0.0099 0.0134 0.0187
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0371 0.0632 0.0884
Giardia lamblia Hypothetical protein 0.0371 0.0632 0.2386
Echinococcus multilocularis neuropeptide Y receptor 0.0094 0.0125 0.0125
Entamoeba histolytica cysteine protease, putative 0.0371 0.0632 0.23
Brugia malayi nuclear hormone receptor 0.0031 0.0009 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0024 0.0086
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0371 0.0632 0.23
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Echinococcus multilocularis tissue type plasminogen activator 0.0141 0.021 0.021
Leishmania major hypothetical protein, conserved 0.0364 0.062 0.1669
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0041 0.0058
Toxoplasma gondii centrin 0.016 0.0246 0.0895
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0225 0.0364 0.0981
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.0017 0.006
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0075 0.0075
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0139 0.0506
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0063 0.0068 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0371 0.0632 0.23
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0094 0.0125 0.0174
Schistosoma mansoni hypothetical protein 0.003 0.0007 0.001
Entamoeba histolytica cysteine proteinase, putative 0.1522 0.2746 1
Echinococcus multilocularis cathepsin L 0.0837 0.1489 0.1489
Toxoplasma gondii microneme protein MIC17C 0.0046 0.0036 0.013
Plasmodium falciparum centrin-4 0.0028 0.0003 0.001
Schistosoma mansoni cathepsin F (C01 family) 0.1055 0.1889 0.2642
Echinococcus granulosus muscleblind protein 0.0151 0.023 0.023
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0048 0.0174
Leishmania major cathepsin L-like protease 0.1522 0.2746 0.7399
Schistosoma mansoni hypothetical protein 0.0865 0.154 0.2154
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0465 0.0805 0.1126
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Trichomonas vaginalis calcium binding protein, putative 0.0188 0.0297 0.1081
Plasmodium vivax aspartyl protease, putative 0.0063 0.0068 0.0248
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Brugia malayi Serotonin receptor 0.0094 0.0125 0.0174
Schistosoma mansoni peroxidasin 0.0109 0.0152 0.0212
Schistosoma mansoni neuronal calcium sensor 0.016 0.0246 0.0344
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.006 0.2543
Echinococcus granulosus glycoprotein Antigen 5 0.0108 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0196 0.0311 0.0435
Echinococcus granulosus neuropeptide Y receptor 0.0094 0.0125 0.0125
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0024 0.0089
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0156 0.0237 0.0332
Trypanosoma cruzi caltractin, putative 0.016 0.0246 0.0344
Toxoplasma gondii kringle domain-containing protein 0.0141 0.021 0.0765
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Mycobacterium tuberculosis Conserved protein 0.0039 0.0024 0.0556
Leishmania major calmodulin, putative 0.016 0.0246 0.0662
Echinococcus multilocularis neuropeptide Y receptor 0.0094 0.0125 0.0125
Schistosoma mansoni caspase-3 (C14 family) 0.0116 0.0164 0.023
Onchocerca volvulus 0.0046 0.0036 0.013
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.003 0.0007 0.001
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0156 0.0237 0.5563
Brugia malayi programmed cell death protein 6 0.016 0.0246 0.0344
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Trypanosoma brucei Calpain-like protein 2 0.0778 0.138 0.3717
Leishmania major phospholipase c-like protein 0.016 0.0246 0.0662
Echinococcus multilocularis neuropeptide receptor A26 0.0094 0.0125 0.0125
Plasmodium falciparum serine repeat antigen 9 0.0371 0.0632 0.23
Loa Loa (eye worm) RNA binding protein 0.0067 0.0075 0.0106
Echinococcus multilocularis programmed cell death protein 0.0188 0.0297 0.0297
Brugia malayi Cell death protein 3 precursor 0.0085 0.0108 0.0151
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Trichomonas vaginalis kakapo, putative 0.0028 0.0003 0.001
Trichomonas vaginalis esterase, putative 0.0039 0.0024 0.0086
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0094 0.0125 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.0364 0.0509
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0031 0.0113
Plasmodium vivax vivapain-1 0.0837 0.1489 0.5422
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.006 0.0084
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0032 0.0118
Schistosoma mansoni thyroid hormone receptor 0.0168 0.0261 0.0365
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0164 0.0253 0.0354
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1522 0.2746 1
Trypanosoma brucei hypothetical protein 0.0701 0.1239 0.3338
Echinococcus granulosus calpain 0.1048 0.1874 0.1874
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0075 0.0106
Echinococcus granulosus centrin 2 0.016 0.0246 0.0246
Brugia malayi Tachykinin-like peptides receptor 99D 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Onchocerca volvulus Peroxidasin homolog 0.0109 0.0152 0.0553
Loa Loa (eye worm) hypothetical protein 0.0467 0.0809 0.1131
Onchocerca volvulus 0.1522 0.2746 1
Trypanosoma cruzi small myristoylated protein 1-2 0.0387 0.0663 0.0927
Loa Loa (eye worm) hypothetical protein 0.0044 0.0032 0.0045
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Leishmania major centrin, putative,caltractin, putative 0.016 0.0246 0.0662
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0007 0.0007
Echinococcus granulosus Tolloid protein 1 0.0116 0.0165 0.0165
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0013 0.0046
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0221 0.0309
Schistosoma mansoni peptidylglycine monooxygenase 0.0247 0.0405 0.0566
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Echinococcus granulosus dro:myosuppressin receptor 0.0094 0.0125 0.0125
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0063 0.0068 0.0095
Plasmodium vivax unspecified product 0.0837 0.1489 0.5422
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0371 0.0632 0.23
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0108 0.0151 0.0211
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.0017 0.006
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Brugia malayi hypothetical protein 0.0109 0.0152 0.0212
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0036 0.013
Loa Loa (eye worm) hypothetical protein 0.0465 0.0805 0.1126
Entamoeba histolytica grainin, putative 0.0164 0.0253 0.0921
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.016 0.0246 0.0344
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0225 0.0364 0.0981
Echinococcus granulosus protein jagged 1 0.003 0.0007 0.0007
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0024 0.0086
Trypanosoma brucei unspecified product 0.0225 0.0364 0.0981
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0108 0.0151 0.0151
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0094 0.0125 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0009 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.006 0.0084
Brugia malayi Probable myosin regulatory light chain 0.0032 0.001 0.0014
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0041 0.0058
Onchocerca volvulus Neurogenic locus notch homolog 0.0034 0.0013 0.0048
Loa Loa (eye worm) hypothetical protein 0.0467 0.0809 0.1131
Schistosoma mansoni cell polarity protein 0.003 0.0007 0.001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0371 0.0632 0.0884
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0622 0.1093 0.1529
Toxoplasma gondii calcium-dependent protein kinase 0.0164 0.0253 0.0921
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0311 0.0311
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0417 0.0716 0.2608
Echinococcus granulosus prefoldin subunit 6 0.0099 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0109 0.0152 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.2048 0.3711 0.5191
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.1215 0.1215
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0213 0.0343 0.0343
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0013 0.0034
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.0139 0.0139
Leishmania major cathepsin L-like protease 0.1522 0.2746 0.7399
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.0118
Trypanosoma cruzi kinesin, putative 0.0631 0.111 0.1553
Toxoplasma gondii calcium binding egf domain-containing protein 0.0055 0.0053 0.0192
Echinococcus granulosus transmembrane protease serine 3 0.0108 0.0151 0.0151
Trypanosoma cruzi cysteine peptidase, putative 0.1522 0.2746 0.3841
Schistosoma mansoni mitochondrial solute carrier 0.016 0.0246 0.0344
Trypanosoma brucei kinesin, putative 0.0631 0.111 0.2991
Schistosoma mansoni centrin 0.016 0.0246 0.0344
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0004
Echinococcus granulosus cathepsin L 0.0837 0.1489 0.1489
Onchocerca volvulus 0.0063 0.0068 0.0248
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Brugia malayi nuclear receptor NHR-88 0.0031 0.0009 0.0012
Schistosoma mansoni centrin-related 0.016 0.0246 0.0344
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0009 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0094 0.0125 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0094 0.0125 0.0125
Echinococcus granulosus survival motor neuron protein 1 0.0482 0.0836 0.0836
Entamoeba histolytica calcium binding family protein 0.016 0.0246 0.0895
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0371 0.0632 0.23
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0371 0.0632 0.23
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0039 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0837 0.1489 0.5422
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0137 0.0204 0.0204
Echinococcus granulosus dnaJ subfamily B 0.0811 0.1441 0.1441
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0009 0.0012
Schistosoma mansoni amine GPCR 0.0094 0.0125 0.0174
Onchocerca volvulus 0.0031 0.0009 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0372 0.0634 0.0887
Loa Loa (eye worm) hypothetical protein 0.0371 0.0632 0.0884
Echinococcus granulosus expressed protein 0.0361 0.0614 0.0614
Brugia malayi cathepsin Z-like cysteine proteinase 0.0371 0.0632 0.0884
Plasmodium vivax proteasome subunit beta type-5, putative 0.0156 0.0237 0.0865
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Echinococcus granulosus cathepsin L cysteine proteinase 0.1522 0.2746 0.2746
Loa Loa (eye worm) matrixin family protein 0.0054 0.0051 0.0072
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0066
Loa Loa (eye worm) hypothetical protein 0.0279 0.0464 0.0649
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0094 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1522 0.2746 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0094 0.0125 0.0125
Onchocerca volvulus 0.0094 0.0125 0.0454
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.0311 0.0311
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0622 0.1093 0.2945
Brugia malayi Cadherin domain containing protein 0.003 0.0007 0.001
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0009 0.0009
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0089 0.0115 0.0115
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.0045
Schistosoma mansoni intermediate filament proteins 0.0057 0.0057 0.008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0094 0.0125 0.0174
Brugia malayi sulfakinin receptor protein 0.0094 0.0125 0.0174
Leishmania major pyruvate kinase 0.0033 0.0013 0.0034
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0041 0.1737
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.001 0.001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0094 0.0125 0.0125
Schistosoma mansoni amine GPCR 0.0094 0.0125 0.0174
Brugia malayi chromobox protein homolog 3 0.0038 0.0022 0.0031
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0116 0.0164 0.0164
Echinococcus multilocularis cathepsin L cysteine protease 0.1522 0.2746 0.2746
Giardia lamblia Cathepsin L precursor 0.0371 0.0632 0.2386
Toxoplasma gondii subtilisin SUB12 0.0046 0.0036 0.013
Loa Loa (eye worm) hypothetical protein 0.0108 0.0151 0.0211
Echinococcus granulosus calcium uptake protein 1 0.0164 0.0253 0.0253
Brugia malayi Probable ATP-dependent helicase DHX35 0.0032 0.001 0.0014
Entamoeba histolytica hypothetical protein 0.0371 0.0632 0.23
Echinococcus granulosus neuropeptides capa receptor 0.0094 0.0125 0.0125
Trypanosoma brucei centrin, putative 0.016 0.0246 0.0662
Trypanosoma cruzi hypothetical protein, conserved 0.0364 0.062 0.0867
Schistosoma mansoni Mername-AA248 (C02 family) 0.1048 0.1874 0.2622
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Onchocerca volvulus 0.0108 0.0151 0.0549
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0017 1
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0028 0.01
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0553 0.0967 0.1353
Trypanosoma brucei calpain-like protein, putative 0.1048 0.1874 0.5051
Onchocerca volvulus 0.1522 0.2746 1
Trypanosoma brucei calmodulin, putative 0.016 0.0246 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.0118
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0075 0.0106
Loa Loa (eye worm) hypothetical protein 0.0052 0.0048 0.0067
Toxoplasma gondii histone lysine methyltransferase SET1 0.017 0.0264 0.0963
Brugia malayi Melatonin receptor type 1A 0.0094 0.0125 0.0174
Brugia malayi AKH receptor 0.0094 0.0125 0.0174
Entamoeba histolytica calpain family cysteine protease, putative 0.0417 0.0716 0.2608
Brugia malayi Cathepsin L-like precursor 0.1522 0.2746 0.3841
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0837 0.1489 0.4012
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.016 0.0246 0.0895
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0032 0.0118
Onchocerca volvulus 0.1522 0.2746 1
Brugia malayi Cadherin domain containing protein 0.003 0.0007 0.001
Giardia lamblia Cysteine protease 0.0371 0.0632 0.2386
Trichomonas vaginalis set domain proteins, putative 0.0752 0.1332 0.4852
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis somatostatin receptor 0.0094 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0056 0.0055 0.0077
Echinococcus multilocularis g protein coupled receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0135 0.0189
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0196 0.0311 0.0435
Schistosoma mansoni neuropeptide receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0009 0.0012
Brugia malayi Delta serrate ligand family protein 0.003 0.0007 0.001
Schistosoma mansoni survival motor neuron protein 0.0098 0.0132 0.0185
Echinococcus multilocularis cathepsin L cysteine protease 0.1522 0.2746 0.2746
Schistosoma mansoni cathepsin F (C01 family) 0.1522 0.2746 0.3841
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0837 0.1489 0.2083
Trichomonas vaginalis calpain, putative 0.0417 0.0716 0.2608
Echinococcus multilocularis chromobox protein 1 0.0069 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0022 0.0081
Leishmania major pyruvate kinase 0.0033 0.0013 0.0034
Onchocerca volvulus 0.0028 0.0003 0.001
Echinococcus multilocularis calpain family protein 1, d 0.1808 0.3269 0.3269
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0063 0.0068 0.0095
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0152 0.0212
Entamoeba histolytica grainin 2 0.0188 0.0297 0.1081
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0797 0.1415 0.1979
Onchocerca volvulus 0.1522 0.2746 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1522 0.2746 0.3841
Trypanosoma cruzi cruzipain precursor, putative 0.0467 0.0809 0.1131
Loa Loa (eye worm) hypothetical protein 0.0057 0.0057 0.008
Echinococcus granulosus proteasome prosome macropain subunit beta 0.012 0.0172 0.0172
Echinococcus granulosus neural cadherin 0.003 0.0007 0.0007
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0049 0.0042 0.0059
Onchocerca volvulus 0.016 0.0246 0.0895
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0156 0.0237 0.0332
Brugia malayi beta-lactamase family protein 0.0039 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.006 0.2543
Onchocerca volvulus Peroxidase homolog 0.0109 0.0152 0.0553
Brugia malayi Calmodulin-like protein 0.016 0.0246 0.0344
Schistosoma mansoni notch 0.003 0.0007 0.001
Plasmodium falciparum proteasome subunit beta type-1, putative 0.012 0.0172 0.0625
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0094 0.0125 0.0125
Echinococcus multilocularis cysteine protease 0.1522 0.2746 0.2746
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0031 0.0113
Leishmania major kinesin, putative 0.0631 0.111 0.2991
Giardia lamblia Cathepsin L precursor 0.0371 0.0632 0.2386
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0024 0.0092
Trichomonas vaginalis centrin, putative 0.0028 0.0003 0.001
Echinococcus granulosus tm gpcr rhodopsin 0.0094 0.0125 0.0125
Brugia malayi Calcium binding EGF domain containing protein 0.0033 0.0013 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.1055 0.1889 0.6879
Schistosoma mansoni hypothetical protein 0.0032 0.001 0.0014
Brugia malayi Calcium binding EGF domain containing protein 0.0041 0.0027 0.0037
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0015 0.0053
Leishmania major calpain protease-like protein 0.0417 0.0716 0.193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1055 0.1889 0.6879
Echinococcus granulosus alpha 1A adrenergic receptor 0.0094 0.0125 0.0125
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0031 0.0113
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0285 0.0474 0.0663
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni notch 0.003 0.0007 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Brugia malayi Cytochrome P450 family protein 0.0049 0.0041 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis muscleblind protein 0.0151 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0039 0.0055
Giardia lamblia Cathepsin B precursor 0.1469 0.2647 1
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0046 0.0036 0.013
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.016 0.0246 0.0895
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0129 0.018
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.003 0.0006 0.0151
Brugia malayi Fibulin-1 precursor 0.0055 0.0053 0.0074
Echinococcus granulosus orexin receptor type 2 0.0094 0.0125 0.0125
Schistosoma mansoni biogenic amine receptor 0.0094 0.0125 0.0174
Echinococcus multilocularis neurocalcin 0.016 0.0246 0.0246
Loa Loa (eye worm) calmodulin-like protein 0.016 0.0246 0.0344
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0045
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0075 0.0106
Echinococcus multilocularis sodium channel protein 0.004 0.0025 0.0025
Toxoplasma gondii aspartyl protease ASP3 0.0063 0.0068 0.0248
Plasmodium falciparum cysteine repeat modular protein 1 0.0141 0.021 0.0765
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0797 0.1415 0.1979
Toxoplasma gondii centrin, putative 0.016 0.0246 0.0895
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0328 0.0554 0.0775
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Trypanosoma cruzi centrin, putative 0.0188 0.0297 0.0415
Echinococcus granulosus calpain A 0.2603 0.4729 0.4729
Trypanosoma cruzi 20S proteasome subunit 0.0049 0.0042 0.0059
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0024 0.0556
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0013 0.0046
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.0038 0.0022 0.0031
Echinococcus granulosus peptide allatostatin:somatostatin 0.0094 0.0125 0.0125
Brugia malayi intermediate filament protein 0.0057 0.0057 0.008
Echinococcus granulosus neuropeptides capa receptor 0.0094 0.0125 0.0125
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0041 0.0111
Echinococcus multilocularis muscleblind protein 1 0.0151 0.023 0.023
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.0017 0.0063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0898 0.16 0.4311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0371 0.0632 0.23
Echinococcus multilocularis geminin 0.0865 0.154 0.154
Loa Loa (eye worm) hypothetical protein 0.0046 0.0036 0.005
Entamoeba histolytica cysteine proteinase, putative 0.1522 0.2746 1
Loa Loa (eye worm) hypothetical protein 0.0371 0.0632 0.0884
Toxoplasma gondii microneme protein MIC17A 0.0046 0.0036 0.013
Schistosoma mansoni reticulocalbin 0.0164 0.0253 0.0354
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Schistosoma mansoni myosin xvIII 0.0094 0.0125 0.0174
Plasmodium falciparum serine repeat antigen 2 0.0371 0.0632 0.23
Loa Loa (eye worm) transcription factor SMAD2 0.0372 0.0634 0.0887
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0009 0.0032
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0094 0.0125 0.0174
Onchocerca volvulus 0.0094 0.0125 0.0454
Onchocerca volvulus 0.0371 0.0632 0.23
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.0017 0.0699
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2599 0.4722 0.4722
Loa Loa (eye worm) animal heme peroxidase 0.0109 0.0152 0.0212
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0002 0.0002
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0009 0.0009
Echinococcus multilocularis neurogenic locus notch protein 0.0033 0.0013 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1253 0.2251 0.3149
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0778 0.138 0.3717
Schistosoma mansoni hypothetical protein 0.0108 0.0151 0.0211
Schistosoma mansoni hypothetical protein 0.0068 0.0077 0.0108
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0641 0.1128 0.1578
Echinococcus multilocularis slit 2 protein 0.003 0.0007 0.0007
Trypanosoma brucei calpain, putative 0.0417 0.0716 0.193
Giardia lamblia Cathepsin L-like protease 0.0371 0.0632 0.2386
Loa Loa (eye worm) neuropeptide F receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0036 0.005
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Echinococcus granulosus neurogenic locus notch protein 4 0.003 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Loa Loa (eye worm) hypothetical protein 0.0371 0.0632 0.0884
Schistosoma mansoni caspase-7 (C14 family) 0.0085 0.0108 0.0151
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0024 0.0086
Echinococcus granulosus EF hand domain containing family member A2 0.016 0.0246 0.0246
Toxoplasma gondii prefoldin subunit 6, putative 0.0099 0.0134 0.0486
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0048 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0023
Brugia malayi Pre-SET motif family protein 0.0661 0.1165 0.163
Schistosoma mansoni myosin light chain 0.0028 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0371 0.0632 0.23
Entamoeba histolytica calpain large subunit domain III containing protein 0.0631 0.111 0.4042
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0013 0.0018
Trichomonas vaginalis bollus pemphigoid antigen, putative 0.0028 0.0003 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0094 0.0125 0.0174
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.0017 0.0023
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0465 0.0805 0.0805
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0024 0.0999
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0013 0.0018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0094 0.0125 0.0125
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0024 0.0086
Schistosoma mansoni neuropeptide receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trypanosoma cruzi major cysteine proteinase, putative 0.0896 0.1597 0.2234
Leishmania major hypothetical protein, conserved 0.0651 0.1146 0.3088
Echinococcus granulosus cathepsin l cysteine peptidase 0.1522 0.2746 0.2746
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Echinococcus granulosus cathepsin b 0.3921 0.7149 0.7149
Brugia malayi Peroxidasin 0.0109 0.0152 0.0212
Brugia malayi hypothetical protein 0.0052 0.0048 0.0067
Trichomonas vaginalis calcium binding proteins, putative 0.016 0.0246 0.0895
Onchocerca volvulus Slit protein homolog 0.003 0.0007 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0094 0.0125 0.0125
Echinococcus granulosus chromobox protein 1 0.0069 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Onchocerca volvulus 0.0094 0.0125 0.0454
Trypanosoma cruzi calmodulin, putative 0.016 0.0246 0.0344
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Entamoeba histolytica cysteine proteinase, putative 0.0837 0.1489 0.5422
Echinococcus granulosus slit 2 protein 0.003 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2048 0.3711 1
Trypanosoma brucei Calpain-like protein 1.2 0.0797 0.1415 0.3813
Echinococcus multilocularis dna polymerase eta 0.0049 0.0041 0.0041
Onchocerca volvulus 0.0046 0.0036 0.013
Onchocerca volvulus 0.0753 0.1333 0.4855
Schistosoma mansoni amine GPCR 0.0094 0.0125 0.0174
Schistosoma mansoni cpg binding protein 0.0091 0.0119 0.0166
Brugia malayi Myosin regulatory light chain 1 0.0028 0.0003 0.0004
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0094 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0094 0.0125 0.0174
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Onchocerca volvulus 0.0108 0.0151 0.0549
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0048 0.0174
Onchocerca volvulus 0.0048 0.0039 0.0143
Loa Loa (eye worm) hypothetical protein 0.0279 0.0464 0.0649
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0139 0.0194
Echinococcus granulosus rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Schistosoma mansoni DNA polymerase eta 0.0049 0.0041 0.0058
Brugia malayi Dopamine receptor protein 1 0.0094 0.0125 0.0174
Schistosoma mansoni opsin-like receptor 0.0094 0.0125 0.0174
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0371 0.0632 0.23
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0049 0.0042 0.0059
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1048 0.1874 0.2622
Plasmodium vivax unspecified product 0.0371 0.0632 0.23
Brugia malayi Cathepsin L-like precursor 0.1522 0.2746 0.3841
Loa Loa (eye worm) hypothetical protein 0.0028 0.0002 0.0003
Schistosoma mansoni slit 0.003 0.0007 0.001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0009 0.0012
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0033 0.0013 0.0018
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0013 0.0018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0024 0.0556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0008 0.003
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0225 0.0364 0.0981
Toxoplasma gondii microneme protein, putative 0.0046 0.0036 0.013
Brugia malayi Trypsin family protein 0.0108 0.0151 0.0211
Entamoeba histolytica prefoldin subunit 6, putative 0.0099 0.0134 0.0486
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0032 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0371 0.0632 0.23
Echinococcus multilocularis neuropeptides capa receptor 0.0094 0.0125 0.0125
Onchocerca volvulus 0.0046 0.0036 0.013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0048 0.0128
Plasmodium falciparum thioredoxin reductase 0.0035 0.0017 0.006
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0077 0.0108
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0094 0.0125 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0017 0.0023
Brugia malayi calcium-binding protein 0.016 0.0246 0.0344
Leishmania major i/6 autoantigen-like protein 0.016 0.0246 0.0662
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0129 0.018
Plasmodium vivax SET domain protein, putative 0.0096 0.0129 0.0469
Loa Loa (eye worm) trypsin family protein 0.0108 0.0151 0.0211
Toxoplasma gondii calmodulin, putative 0.0028 0.0003 0.001
Giardia lamblia Proteasome subunit beta type 2 0.0049 0.0042 0.0158
Loa Loa (eye worm) hypothetical protein 0.0085 0.0108 0.0151
Brugia malayi cathepsin L precursor 0.0371 0.0632 0.0884
Brugia malayi GnHR receptor homolog 0.0094 0.0125 0.0174
Giardia lamblia Cysteine protease 0.0371 0.0632 0.2386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0002 0.0006
Echinococcus granulosus cathepsin L 0.0371 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0108 0.0151 0.0211
Loa Loa (eye worm) hypothetical protein 0.016 0.0246 0.0344
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0032 0.0045
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0641 0.1128 0.1578
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1522 0.2746 0.2746
Giardia lamblia Cathepsin B precursor 0.0371 0.0632 0.2386
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1469 0.2647 0.3703
Loa Loa (eye worm) hypothetical protein 0.0151 0.023 0.0321
Brugia malayi hypothetical protein 0.0482 0.0836 0.1169
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0094 0.0125 0.0174
Loa Loa (eye worm) TYRA-2 protein 0.0094 0.0125 0.0174
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0371 0.0632 0.23
Echinococcus multilocularis neuropeptide receptor 0.0094 0.0125 0.0125
Echinococcus granulosus neuronal calcium sensor 0.016 0.0246 0.0246
Trypanosoma cruzi conserved protein 0.0651 0.1146 0.1603
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.012 0.0172 0.024
Leishmania major DNA polymerase eta, putative 0.0034 0.0015 0.0039
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.0017 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0328 0.0554 0.1493
Brugia malayi Matrixin family protein 0.0059 0.006 0.0085
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0156 0.0237 0.5563
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0371 0.0632 0.23
Echinococcus granulosus g protein coupled receptor 0.0094 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0063 0.0067 0.0093
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0017 0.0045
Echinococcus multilocularis serotonin receptor 0.0094 0.0125 0.0125
Plasmodium falciparum metacaspase-like protein 0.0044 0.0032 0.0118
Brugia malayi EGF-like domain containing protein 0.003 0.0007 0.001
Onchocerca volvulus Chorion peroxidase homolog 0.0109 0.0152 0.0553
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0075 0.0106
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0837 0.1489 0.2083
Echinococcus granulosus protein jagged 2 0.003 0.0007 0.0007
Loa Loa (eye worm) aspartyl protease 6 0.0063 0.0068 0.0095
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.0017 0.006
Echinococcus granulosus protein jagged 2 0.003 0.0007 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.0311 0.0311
Leishmania major DNA polymerase eta, putative 0.0049 0.0041 0.0111
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0285 0.0474 0.1278
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Plasmodium vivax plasmepsin IV, putative 0.0213 0.0343 0.125
Brugia malayi cathepsin F-like cysteine proteinase 0.0371 0.0632 0.0884
Loa Loa (eye worm) hypothetical protein 0.0096 0.0129 0.018
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0221 0.0309
Brugia malayi hypothetical protein 0.0094 0.0125 0.0174
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0837 0.1489 0.2083
Echinococcus granulosus g-protein coupled receptor 0.0094 0.0125 0.0125
Brugia malayi cathepsin L-like cysteine proteinase 0.0371 0.0632 0.0884
Echinococcus granulosus microtubule associated protein 2 0.0688 0.1215 0.1215
Leishmania major calpain family cysteine protease-like protein 0.0641 0.1128 0.3041
Leishmania major hypothetical protein, conserved 0.0225 0.0364 0.0981
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0022 0.0081
Echinococcus granulosus tm gpcr rhodopsin 0.0094 0.0125 0.0125
Schistosoma mansoni cercarial elastase (S01 family) 0.0108 0.0151 0.0211
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0036 0.005
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0371 0.0632 0.23
Echinococcus multilocularis protein jagged 1 0.003 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0041 0.0058
Schistosoma mansoni biogenic amine (5HT) receptor 0.0094 0.0125 0.0174
Entamoeba histolytica calcium-binding protein, putative 0.016 0.0246 0.0895
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0024 0.0064
Trichomonas vaginalis calcineurin B subunit, putative 0.0164 0.0253 0.0921
Schistosoma mansoni hypothetical protein 0.0417 0.0716 0.1002
Echinococcus granulosus Myosin regulatory light chain 0.0028 0.0003 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Echinococcus granulosus G protein coupled receptor 139 0.0094 0.0125 0.0125
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0156 0.0237 0.0865
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0233 0.0379 0.8882
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0009 0.0012
Echinococcus multilocularis tachykinin peptides receptor 99D 0.5475 1 1
Giardia lamblia Cathepsin B precursor 0.0371 0.0632 0.2386
Echinococcus multilocularis g protein coupled receptor 0.0094 0.0125 0.0125
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.1215 0.17
Entamoeba histolytica cysteine protease, putative 0.0837 0.1489 0.5422
Onchocerca volvulus 0.0046 0.0036 0.013
Loa Loa (eye worm) hypothetical protein 0.0108 0.0151 0.0211
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0094 0.0125 0.0125
Plasmodium falciparum thioredoxin reductase 0.0102 0.0139 0.0506
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1332 0.2397 0.3353
Trypanosoma brucei antigen, putative 0.1048 0.1874 0.5051
Echinococcus granulosus neurocalcin 0.016 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Brugia malayi Animal haem peroxidase family protein 0.0109 0.0152 0.0212
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0225 0.0364 0.0981
Entamoeba histolytica cysteine protease, putative 0.1522 0.2746 1
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0013 0.0046
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0108 0.0151 0.0211
Echinococcus granulosus programmed cell death protein 6 0.0032 0.001 0.001
Loa Loa (eye worm) calpain D 0.0417 0.0716 0.1002
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0013 0.0299
Plasmodium falciparum serine repeat antigen 5 0.0371 0.0632 0.23
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0125 0.0182 0.0254
Giardia lamblia Cathepsin L precursor 0.0371 0.0632 0.2386
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0186 0.0294 0.0411
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0094 0.0125 0.0174
Echinococcus multilocularis lamin dm0 0.0057 0.0057 0.0057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0119 0.0119
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0009 0.0012
Plasmodium vivax prefoldin subunit 6, putative 0.0099 0.0134 0.0486
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0094 0.0125 0.0174
Echinococcus multilocularis fibropellin Ia 0.003 0.0007 0.0007
Trichomonas vaginalis calmodulin, putative 0.016 0.0246 0.0895
Brugia malayi hypothetical protein 0.0063 0.0068 0.0095
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0013 0.0018
Onchocerca volvulus 0.0046 0.0036 0.013
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0024 0.0556
Onchocerca volvulus 0.0046 0.0036 0.013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1522 0.2746 1
Plasmodium falciparum plasmepsin V 0.0063 0.0068 0.0248
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Trichomonas vaginalis centrin, putative 0.016 0.0246 0.0895
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.003 0.0006 0.0009
Echinococcus granulosus intermediate filament protein 0.0057 0.0057 0.0057
Onchocerca volvulus 0.0094 0.0125 0.0454
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.001 0.001
Giardia lamblia Encystation-specific protease 0.0371 0.0632 0.2386
Entamoeba histolytica cysteine proteinase, putative 0.0837 0.1489 0.5422
Leishmania major cytochrome p450-like protein 0.0049 0.0041 0.0111
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0009 0.0012
Onchocerca volvulus 0.003 0.0007 0.0026
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.016 0.0246 0.0662
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2439 0.4428 0.6193
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0371 0.0632 0.0884
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0371 0.0632 0.0884
Trypanosoma cruzi metacaspase, putative 0.0044 0.0032 0.0045
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0641 0.1128 0.3041
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0259 0.0427 1
Brugia malayi hypothetical protein 0.0063 0.0068 0.0095
Plasmodium falciparum plasmepsin VI 0.0213 0.0343 0.125
Leishmania major proteasome beta 2 subunit, putative 0.0049 0.0042 0.0113
Trypanosoma brucei Calpain-like protein CALP1.3 0.0641 0.1128 0.3041
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0135 0.0189
Loa Loa (eye worm) hypothetical protein 0.0094 0.0125 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0094 0.0125 0.0125
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0032 0.0045
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0013 0.0537
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3921 0.7149 1
Schistosoma mansoni dopamine-beta-monooxygenase 0.0247 0.0405 0.0566
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0024 0.0086
Loa Loa (eye worm) hypothetical protein 0.003 0.0007 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0009 0.0009
Trypanosoma cruzi cysteine proteinase, putative 0.0837 0.1489 0.2083
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0371 0.0632 0.23
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0417 0.0716 0.2608
Leishmania major small myristoylated protein-1 0.0387 0.0663 0.1786
Schistosoma mansoni coup transcription factor 0.0031 0.0009 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0701 0.1239 0.3338

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.04 ug ml-1 In vitro cytotoxicity activity against human stomach cancer cell lines SNU-5 ChEMBL. 8182706
IC50 (functional) = 1.06 ug ml-1 In vitro cytotoxicity activity against human stomach cancer cell lines SNU-16 ChEMBL. 8182706
IC50 (functional) = 7.5 ug ml-1 In vitro cytotoxicity activity against human stomach cancer cell lines SNU-1 ChEMBL. 8182706
IC50 (functional) = 16.2 ug ml-1 In vitro cytotoxicity activity against human stomach cancer cell lines NCI-N87 ChEMBL. 8182706
T/C (functional) = 112 % Antitumor activity against L1210 Leukemia cells in mice at their respective dose at 3.1mg/kg,ip,days ChEMBL. 8182706
T/C (functional) = 179 % Antitumor activity against L1210 Leukemia cells in mice at 6.25 mg/kg ChEMBL. 8182706
T/C (functional) = 201 % Antitumor activity against L1210 Leukemia cells in mice at 12.5 mg/kg ChEMBL. 8182706

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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